pyruvaldehyde has been researched along with Multiple Sclerosis in 3 studies
Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.
Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 3 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Wetzels, S | 2 |
Vanmierlo, T | 2 |
Scheijen, JLJM | 1 |
van Horssen, J | 1 |
Amor, S | 1 |
Somers, V | 1 |
Schalkwijk, CG | 2 |
Hendriks, JJA | 1 |
Wouters, K | 2 |
Hendriks, JJ | 1 |
Gonzalo, H | 1 |
Brieva, L | 1 |
Tatzber, F | 1 |
Jové, M | 1 |
Cacabelos, D | 1 |
Cassanyé, A | 1 |
Lanau-Angulo, L | 1 |
Boada, J | 1 |
Serrano, JC | 1 |
González, C | 1 |
Hernández, L | 1 |
Peralta, S | 1 |
Pamplona, R | 1 |
Portero-Otin, M | 1 |
1 review available for pyruvaldehyde and Multiple Sclerosis
Article | Year |
---|---|
Methylglyoxal-Derived Advanced Glycation Endproducts in Multiple Sclerosis.
Topics: Adaptive Immunity; Animals; Glycation End Products, Advanced; Glycolysis; Humans; Immunity, Innate; | 2017 |
2 other studies available for pyruvaldehyde and Multiple Sclerosis
Article | Year |
---|---|
Methylglyoxal-Derived Advanced Glycation Endproducts Accumulate in Multiple Sclerosis Lesions.
Topics: Aged; Astrocytes; Biomarkers; Disease Progression; Disease Susceptibility; Female; Glycation End Pro | 2019 |
Lipidome analysis in multiple sclerosis reveals protein lipoxidative damage as a potential pathogenic mechanism.
Topics: Adult; Autoantibodies; Cell Line, Transformed; Chromatography, High Pressure Liquid; Fatty Acids; Fe | 2012 |