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pyruvaldehyde and Multiple Sclerosis

pyruvaldehyde has been researched along with Multiple Sclerosis in 3 studies

Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.

Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wetzels, S2
Vanmierlo, T2
Scheijen, JLJM1
van Horssen, J1
Amor, S1
Somers, V1
Schalkwijk, CG2
Hendriks, JJA1
Wouters, K2
Hendriks, JJ1
Gonzalo, H1
Brieva, L1
Tatzber, F1
Jové, M1
Cacabelos, D1
Cassanyé, A1
Lanau-Angulo, L1
Boada, J1
Serrano, JC1
González, C1
Hernández, L1
Peralta, S1
Pamplona, R1
Portero-Otin, M1

Reviews

1 review available for pyruvaldehyde and Multiple Sclerosis

ArticleYear
Methylglyoxal-Derived Advanced Glycation Endproducts in Multiple Sclerosis.
    International journal of molecular sciences, 2017, Feb-15, Volume: 18, Issue:2

    Topics: Adaptive Immunity; Animals; Glycation End Products, Advanced; Glycolysis; Humans; Immunity, Innate;

2017

Other Studies

2 other studies available for pyruvaldehyde and Multiple Sclerosis

ArticleYear
Methylglyoxal-Derived Advanced Glycation Endproducts Accumulate in Multiple Sclerosis Lesions.
    Frontiers in immunology, 2019, Volume: 10

    Topics: Aged; Astrocytes; Biomarkers; Disease Progression; Disease Susceptibility; Female; Glycation End Pro

2019
Lipidome analysis in multiple sclerosis reveals protein lipoxidative damage as a potential pathogenic mechanism.
    Journal of neurochemistry, 2012, Volume: 123, Issue:4

    Topics: Adult; Autoantibodies; Cell Line, Transformed; Chromatography, High Pressure Liquid; Fatty Acids; Fe

2012