pyruvaldehyde has been researched along with Leukemia in 12 studies
Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (75.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| FREIREICH, EJ | 1 |
| FREI, E | 1 |
| KARON, M | 1 |
| REGELSON, W | 1 |
| HOLLAND, JR | 1 |
| BURCHENAL, JH | 1 |
| PURPLE, JR | 1 |
| BUCHOLZ, E | 1 |
| STRAUB, PW | 1 |
| MIHICH, E | 1 |
| BERNARD, J | 2 |
| BOIRON, M | 1 |
| JACQUILLAT, C | 2 |
| WEIL, M | 2 |
| SHAW, RK | 1 |
| CREGER, WP | 1 |
| FIELD, M | 2 |
| BLOCK, JB | 2 |
| OLIVERIO, VT | 2 |
| RALL, DP | 1 |
| BAIRON, M | 1 |
| Westwood, ME | 1 |
| Thornalley, PJ | 1 |
| Biswas, S | 1 |
| Ray, M | 2 |
| Misra, S | 1 |
| Dutta, DP | 1 |
| Ray, S | 2 |
| Halder, J | 1 |
| Dutta, SK | 1 |
1 review available for pyruvaldehyde and Leukemia
| Article | Year |
|---|---|
CURRENT STUDIES WITH METHYLGLYOXAL-BIS(GUANYLHYDRAZONE).
Topics: Antineoplastic Agents; Hypoglycemia; Leukemia; Liver Glycogen; Neoplasms; Pharmacology; Pyruvaldehyd | 1963 |
11 other studies available for pyruvaldehyde and Leukemia
| Article | Year |
|---|---|
Methylglyoxal bis (guanylhydrazone): a new agent active against acute myelocytic leukemia.
Topics: Amidines; Antineoplastic Agents; Humans; Hydrazines; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, | 1962 |
Clinical experience with methylglyoxal bis (guanylhydrazone) dihydrochloride: a new agent with clinical activity in acute myelocytic leukemia and the lymphomas.
Topics: Antineoplastic Agents; Humans; Hydrazines; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Ly | 1963 |
Potentiation of methylglyoxal bis(guanylhydrazone) by stilbamidine in transplanted mouse leukemia.
Topics: Animals; Antineoplastic Agents; Guanidine; Guanidines; Leukemia; Leukemia, Experimental; Mice; Mitog | 1963 |
[PRELIMINARY RESULTS OF THE ASSOCIATION OF METHYLGLYOXAL-BIS(GUANYLHYDRAZONE AND 6-MERCAPTOPURINE IN THE TREATMENT OF ACUTE LEUKEMIAS OF THE GRANULOCYTIC SERIES].
Topics: Guanidines; Humans; Leukemia; Leukemia, Myeloid; Mercaptopurine; Mitoguazone; Pyruvaldehyde; Toxicol | 1964 |
METHYLGLYOXAL BIS(GUANYLHYDRAZONE), NSC-32946, 1 IN THE TREATMENT OF ACUTE MYELOBLASTIC AND MONOBLASTIC LEUKEMIA IN ADULTS.
Topics: Antimetabolites; Antineoplastic Agents; Biomedical Research; Blood Chemical Analysis; Dermatology; G | 1964 |
CELLULAR ACCUMULATION OF METHYLGLYOXAL-BIS-GUANYLHYDRAZONE IN VITRO. I. GENERAL CHARACTERISTICS OF CELLULAR UPTAKE.
Topics: Amines; Animals; Antineoplastic Agents; Anura; Biological Transport; Erythrocytes; Fishes; In Vitro | 1964 |
CELLULAR ACCUMULATION OF METHYLGLYOXAL-BIS-GUANYLHYDRAZONE IN VITRO. II. STUDIES ON THE MECHANISM OF ACCUMULATION IN LEUKEMIC LEUKOCYTES.
Topics: Antineoplastic Agents; Biological Transport; Carbon Isotopes; Hydrogen-Ion Concentration; In Vitro T | 1964 |
COMBINATION OF METHYLGLYOXAL BIS(GUANYLHYDRAZONE) (NSC-32946)AND 6-MERCAPTOPURINE (NSC-755) IN ACUTE GRANULOCYTIC LEUKEMIA.
Topics: Drug Therapy; Guanidines; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopur | 1965 |
Induction of synthesis and secretion of interleukin 1 beta in the human monocytic THP-1 cells by human serum albumins modified with methylglyoxal and advanced glycation endproducts.
Topics: Glycation End Products, Advanced; Humans; Interleukin-1; Leukemia; Monocytes; Pyruvaldehyde; Serum A | 1996 |
Selective inhibition of mitochondrial respiration and glycolysis in human leukaemic leucocytes by methylglyoxal.
Topics: Adenosine Triphosphate; Adolescent; Adult; Aldehydes; Cell Respiration; Child; Female; Glycolysis; H | 1997 |
Inhibition of respiration of tumor cells by methylglyoxal and protection of inhibition by lactaldehyde.
Topics: Aldehydes; Animals; Ascorbic Acid; Carcinoma, Ehrlich Tumor; Cell Survival; Female; Humans; In Vitro | 1991 |