Page last updated: 2024-10-19

pyruvaldehyde and Leukemia

pyruvaldehyde has been researched along with Leukemia in 12 studies

Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.

Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19909 (75.00)18.7374
1990's3 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
FREIREICH, EJ1
FREI, E1
KARON, M1
REGELSON, W1
HOLLAND, JR1
BURCHENAL, JH1
PURPLE, JR1
BUCHOLZ, E1
STRAUB, PW1
MIHICH, E1
BERNARD, J2
BOIRON, M1
JACQUILLAT, C2
WEIL, M2
SHAW, RK1
CREGER, WP1
FIELD, M2
BLOCK, JB2
OLIVERIO, VT2
RALL, DP1
BAIRON, M1
Westwood, ME1
Thornalley, PJ1
Biswas, S1
Ray, M2
Misra, S1
Dutta, DP1
Ray, S2
Halder, J1
Dutta, SK1

Reviews

1 review available for pyruvaldehyde and Leukemia

ArticleYear
CURRENT STUDIES WITH METHYLGLYOXAL-BIS(GUANYLHYDRAZONE).
    Cancer research, 1963, Volume: 23

    Topics: Antineoplastic Agents; Hypoglycemia; Leukemia; Liver Glycogen; Neoplasms; Pharmacology; Pyruvaldehyd

1963

Other Studies

11 other studies available for pyruvaldehyde and Leukemia

ArticleYear
Methylglyoxal bis (guanylhydrazone): a new agent active against acute myelocytic leukemia.
    Cancer chemotherapy reports, 1962, Volume: 16

    Topics: Amidines; Antineoplastic Agents; Humans; Hydrazines; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid,

1962
Clinical experience with methylglyoxal bis (guanylhydrazone) dihydrochloride: a new agent with clinical activity in acute myelocytic leukemia and the lymphomas.
    Cancer chemotherapy reports, 1963, Volume: 27

    Topics: Antineoplastic Agents; Humans; Hydrazines; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Ly

1963
Potentiation of methylglyoxal bis(guanylhydrazone) by stilbamidine in transplanted mouse leukemia.
    Cancer chemotherapy reports, 1963, Volume: 29

    Topics: Animals; Antineoplastic Agents; Guanidine; Guanidines; Leukemia; Leukemia, Experimental; Mice; Mitog

1963
[PRELIMINARY RESULTS OF THE ASSOCIATION OF METHYLGLYOXAL-BIS(GUANYLHYDRAZONE AND 6-MERCAPTOPURINE IN THE TREATMENT OF ACUTE LEUKEMIAS OF THE GRANULOCYTIC SERIES].
    La Presse medicale, 1964, Volume: 72

    Topics: Guanidines; Humans; Leukemia; Leukemia, Myeloid; Mercaptopurine; Mitoguazone; Pyruvaldehyde; Toxicol

1964
METHYLGLYOXAL BIS(GUANYLHYDRAZONE), NSC-32946, 1 IN THE TREATMENT OF ACUTE MYELOBLASTIC AND MONOBLASTIC LEUKEMIA IN ADULTS.
    Cancer chemotherapy reports, 1964, Volume: 36

    Topics: Antimetabolites; Antineoplastic Agents; Biomedical Research; Blood Chemical Analysis; Dermatology; G

1964
CELLULAR ACCUMULATION OF METHYLGLYOXAL-BIS-GUANYLHYDRAZONE IN VITRO. I. GENERAL CHARACTERISTICS OF CELLULAR UPTAKE.
    Cancer research, 1964, Volume: 24

    Topics: Amines; Animals; Antineoplastic Agents; Anura; Biological Transport; Erythrocytes; Fishes; In Vitro

1964
CELLULAR ACCUMULATION OF METHYLGLYOXAL-BIS-GUANYLHYDRAZONE IN VITRO. II. STUDIES ON THE MECHANISM OF ACCUMULATION IN LEUKEMIC LEUKOCYTES.
    Cancer research, 1964, Volume: 24

    Topics: Antineoplastic Agents; Biological Transport; Carbon Isotopes; Hydrogen-Ion Concentration; In Vitro T

1964
COMBINATION OF METHYLGLYOXAL BIS(GUANYLHYDRAZONE) (NSC-32946)AND 6-MERCAPTOPURINE (NSC-755) IN ACUTE GRANULOCYTIC LEUKEMIA.
    Cancer chemotherapy reports, 1965, Volume: 45

    Topics: Drug Therapy; Guanidines; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopur

1965
Induction of synthesis and secretion of interleukin 1 beta in the human monocytic THP-1 cells by human serum albumins modified with methylglyoxal and advanced glycation endproducts.
    Immunology letters, 1996, Volume: 50, Issue:1-2

    Topics: Glycation End Products, Advanced; Humans; Interleukin-1; Leukemia; Monocytes; Pyruvaldehyde; Serum A

1996
Selective inhibition of mitochondrial respiration and glycolysis in human leukaemic leucocytes by methylglyoxal.
    The Biochemical journal, 1997, Apr-15, Volume: 323 ( Pt 2)

    Topics: Adenosine Triphosphate; Adolescent; Adult; Aldehydes; Cell Respiration; Child; Female; Glycolysis; H

1997
Inhibition of respiration of tumor cells by methylglyoxal and protection of inhibition by lactaldehyde.
    International journal of cancer, 1991, Feb-20, Volume: 47, Issue:4

    Topics: Aldehydes; Animals; Ascorbic Acid; Carcinoma, Ehrlich Tumor; Cell Survival; Female; Humans; In Vitro

1991