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pyruvaldehyde and Kidney Failure, Chronic

pyruvaldehyde has been researched along with Kidney Failure, Chronic in 18 studies

Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.

Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.

Research Excerpts

ExcerptRelevanceReference
"OX-LDL from chronic renal failure patients on both PD and HD stimulated greater adhesion than OX-LDL from the C subjects (68."2.70Low-density lipoprotein (LDL)-induced monocyte-endothelial cell adhesion, soluble cell adhesion molecules, and autoantibodies to oxidized-LDL in chronic renal failure patients on dialysis therapy. ( Collazo, R; Devaraj, S; Grundy, S; Islam, KN; Jialal, I; McDonald, L; O'Byrne, D, 2001)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (11.11)18.2507
2000's15 (83.33)29.6817
2010's1 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tezuka, Y1
Nakaya, I1
Nakayama, K3
Nakayama, M3
Yahata, M1
Soma, J1
Kabayama, S1
Nakano, H1
Zhu, WJ2
Terawaki, H2
Katoh, K1
Satoh, T1
Ito, S2
Karg, E1
Papp, F1
Tassi, N1
Janáky, T1
Wittmann, G1
Túri, S1
Talukdar, D1
Chaudhuri, BS1
Ray, M1
Ray, S1
Inagi, R2
Miyata, T2
Ueda, Y2
Yoshino, A2
Nangaku, M1
van Ypersele de Strihou, C2
Kurokawa, K2
Zeier, M1
Schwenger, V1
Deppisch, R1
Haug, U1
Weigel, K1
Bahner, U1
Wanner, C1
Schneider, H1
Henle, T1
Ritz, E1
Uribarri, J1
Peppa, M1
Cai, W1
Goldberg, T1
Lu, M1
Baliga, S1
Vassalotti, JA1
Vlassara, H1
Ward, RA1
McLeish, KR1
Lapolla, A2
Reitano, R2
Seraglia, R2
Sartore, G1
Ragazzi, E2
Traldi, P2
Flamini, R1
Lupo, A1
Aricò, NC1
Rugiu, C1
Tubaro, M1
Rabbani, N1
Sebekova, K2
Heidland, A1
Thornalley, PJ1
Shirota, Y1
Sato, T1
Kohno, M1
Odani, H2
Shinzato, T2
Usami, J2
Matsumoto, Y2
Brinkmann Frye, E1
Baynes, JW1
Maeda, K2
Takeuchi, M1
Makita, Z1
Bucala, R1
Suzuki, T1
Koike, T1
Kameda, Y1
Goffin, E1
Ishibashi, Y1
Izuhara, Y1
Saito, A1
O'Byrne, D1
Devaraj, S1
Islam, KN1
Collazo, R1
McDonald, L1
Grundy, S1
Jialal, I1
Nohara, Y1
Usui, T1
Kinoshita, T1
Watanabe, M1

Trials

4 trials available for pyruvaldehyde and Kidney Failure, Chronic

ArticleYear
Biological effects of electrolyzed water in hemodialysis.
    Nephron. Clinical practice, 2009, Volume: 112, Issue:1

    Topics: Adult; Aged; Cytochromes c; Electrodes; Electrolysis; Feasibility Studies; Female; Hemodialysis Solu

2009
Glucose degradation products in PD fluids: do they disappear from the peritoneal cavity and enter the systemic circulation?
    Kidney international, 2003, Volume: 63, Issue:1

    Topics: Adult; Ascitic Fluid; CA-125 Antigen; Cross-Over Studies; Deoxyglucose; Female; Fluorescence; Glucos

2003
Effect of dwell time on carbonyl stress using icodextrin and amino acid peritoneal dialysis fluids.
    Kidney international, 2000, Volume: 58, Issue:6

    Topics: Aged; Amino Acids; Arginine; Deoxyglucose; Dialysis Solutions; Female; Filtration; Glucans; Glucose;

2000
Low-density lipoprotein (LDL)-induced monocyte-endothelial cell adhesion, soluble cell adhesion molecules, and autoantibodies to oxidized-LDL in chronic renal failure patients on dialysis therapy.
    Metabolism: clinical and experimental, 2001, Volume: 50, Issue:2

    Topics: Adult; Arteriosclerosis; Autoantibodies; Case-Control Studies; Cell Adhesion; Cell Adhesion Molecule

2001

Other Studies

14 other studies available for pyruvaldehyde and Kidney Failure, Chronic

ArticleYear
Methylglyoxal as a prognostic factor in patients with chronic kidney disease.
    Nephrology (Carlton, Vic.), 2019, Volume: 24, Issue:9

    Topics: Aged; Arginine; Biomarkers; Cardiovascular Diseases; Deoxyglucose; Diabetic Nephropathies; Disease P

2019
Enhanced methylglyoxal formation in the erythrocytes of hemodialyzed patients.
    Metabolism: clinical and experimental, 2009, Volume: 58, Issue:7

    Topics: Adult; Case-Control Studies; Erythrocytes; Female; Glutathione; Humans; Kidney Failure, Chronic; Lac

2009
Critical evaluation of toxic versus beneficial effects of methylglyoxal.
    Biochemistry. Biokhimiia, 2009, Volume: 74, Issue:10

    Topics: Animals; Arginine; Cataract; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Delive

2009
Efficient in vitro lowering of carbonyl stress by the glyoxalase system in conventional glucose peritoneal dialysis fluid.
    Kidney international, 2002, Volume: 62, Issue:2

    Topics: Animals; CHO Cells; Cricetinae; Deoxyglucose; Dialysis Solutions; Gene Expression Regulation, Enzymo

2002
Dietary glycotoxins correlate with circulating advanced glycation end product levels in renal failure patients.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 42, Issue:3

    Topics: Cross-Sectional Studies; Diabetes Complications; Diabetes Mellitus; Diet; Diet Records; Food Analysi

2003
Methylglyoxal: a stimulus to neutrophil oxygen radical production in chronic renal failure?
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2004, Volume: 19, Issue:7

    Topics: Exocytosis; Humans; Kidney Failure, Chronic; Neutrophils; p38 Mitogen-Activated Protein Kinases; Pyr

2004
Evaluation of advanced glycation end products and carbonyl compounds in patients with different conditions of oxidative stress.
    Molecular nutrition & food research, 2005, Volume: 49, Issue:7

    Topics: Aged; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Dialysis Solutions; Glycated Hemoglobin; G

2005
Evaluation of glyoxal and methylglyoxal levels in uremic patients under peritoneal dialysis.
    Annals of the New York Academy of Sciences, 2005, Volume: 1043

    Topics: Aged; Blood Proteins; Female; Glyoxal; Humans; Kidney Failure, Chronic; Male; Middle Aged; Peritonea

2005
Accumulation of free adduct glycation, oxidation, and nitration products follows acute loss of renal function.
    Kidney international, 2007, Volume: 72, Issue:9

    Topics: Animals; Body Weight; Disease Models, Animal; Glycation End Products, Advanced; Glyoxal; Kidney Fail

2007
Polymorphonuclear leukocyte injury by methylglyoxal and hydrogen peroxide: a possible pathological role for enhanced oxidative stress in chronic kidney disease.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:10

    Topics: Apoptosis; Cell Survival; Drug Synergism; Free Radicals; Humans; Hydrogen Peroxide; In Vitro Techniq

2008
Imidazolium crosslinks derived from reaction of lysine with glyoxal and methylglyoxal are increased in serum proteins of uremic patients: evidence for increased oxidative stress in uremia.
    FEBS letters, 1998, May-15, Volume: 427, Issue:3

    Topics: Cross-Linking Reagents; Female; Glyoxal; Humans; Imidazoles; Kidney Failure, Chronic; Lysine; Male;

1998
Increase in three alpha,beta-dicarbonyl compound levels in human uremic plasma: specific in vivo determination of intermediates in advanced Maillard reaction.
    Biochemical and biophysical research communications, 1999, Mar-05, Volume: 256, Issue:1

    Topics: 2-Naphthylamine; Aging; Arginine; Chromatography, Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; G

1999
Immunological evidence that non-carboxymethyllysine advanced glycation end-products are produced from short chain sugars and dicarbonyl compounds in vivo.
    Molecular medicine (Cambridge, Mass.), 2000, Volume: 6, Issue:2

    Topics: Animals; Antibodies; Cattle; Chromatography, Affinity; Cross Reactions; Diabetes Mellitus, Type 2; E

2000
Generation of superoxide anions during the reaction of guanidino compounds with methylglyoxal.
    Chemical & pharmaceutical bulletin, 2002, Volume: 50, Issue:2

    Topics: Guanidine; Guanidines; Humans; Kidney Failure, Chronic; Oxidative Stress; Pyruvaldehyde; Superoxides

2002