pyruvaldehyde has been researched along with Ischemia in 7 studies
Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Hanssen, NMJ | 1 |
| Teraa, M | 1 |
| Scheijen, JLJM | 1 |
| Van de Waarenburg, M | 1 |
| Gremmels, H | 1 |
| Stehouwer, CDA | 1 |
| Verhaar, MC | 1 |
| Schalkwijk, CG | 1 |
| Nguyen, H | 1 |
| Koh, JY | 1 |
| Li, H | 1 |
| Islas-Robles, A | 1 |
| Meda Venkata, SP | 1 |
| Wang, JM | 1 |
| Monks, TJ | 1 |
| Rodrigues, T | 1 |
| Matafome, P | 1 |
| Seiça, R | 1 |
| Vulesevic, B | 1 |
| McNeill, B | 1 |
| Geoffrion, M | 1 |
| Kuraitis, D | 1 |
| McBane, JE | 1 |
| Lochhead, M | 1 |
| Vanderhyden, BC | 1 |
| Korbutt, GS | 1 |
| Milne, RW | 1 |
| Suuronen, EJ | 1 |
| Kim, D | 1 |
| Fiske, BP | 1 |
| Birsoy, K | 1 |
| Freinkman, E | 1 |
| Kami, K | 1 |
| Possemato, RL | 1 |
| Chudnovsky, Y | 1 |
| Pacold, ME | 1 |
| Chen, WW | 1 |
| Cantor, JR | 1 |
| Shelton, LM | 1 |
| Gui, DY | 1 |
| Kwon, M | 1 |
| Ramkissoon, SH | 1 |
| Ligon, KL | 1 |
| Kang, SW | 1 |
| Snuderl, M | 1 |
| Vander Heiden, MG | 1 |
| Sabatini, DM | 1 |
| Wang, L | 1 |
| Zhang, X | 1 |
| Pang, N | 1 |
| Xiao, L | 1 |
| Li, Y | 1 |
| Chen, N | 1 |
| Ren, M | 1 |
| Deng, X | 1 |
| Wu, J | 1 |
| Ceradini, DJ | 1 |
| Yao, D | 1 |
| Grogan, RH | 1 |
| Callaghan, MJ | 1 |
| Edelstein, D | 1 |
| Brownlee, M | 1 |
| Gurtner, GC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intra-arterial Infusion of Autologous Bone Marrow Mononuclear Cells in Patients With Chronic Critical Limb Ischemia: a Randomized, Placebo-controlled Clinical Trial[NCT00371371] | Phase 1/Phase 2 | 160 participants (Actual) | Interventional | 2006-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 other studies available for pyruvaldehyde and Ischemia
| Article | Year |
|---|---|
Plasma Methylglyoxal Levels Are Associated With Amputations and Mortality in Severe Limb Ischemia Patients With and Without Diabetes.
Topics: Amputation, Surgical; Cardiovascular Diseases; Case-Control Studies; Diabetes Mellitus; Female; Glyc | 2021 |
A novel imidazolinone metformin-methylglyoxal metabolite promotes endothelial cell angiogenesis via the eNOS/HIF-1α pathway.
Topics: Animals; Hindlimb; Hyperglycemia; Hypoglycemic Agents; Hypoxia-Inducible Factor 1, alpha Subunit; Im | 2021 |
Methylglyoxal further impairs adipose tissue metabolism after partial decrease of blood supply.
Topics: Adipose Tissue; Animals; Biomarkers; Epididymis; Glycosylation; Ischemia; Male; Postoperative Compli | 2013 |
Glyoxalase-1 overexpression in bone marrow cells reverses defective neovascularization in STZ-induced diabetic mice.
Topics: Angiogenic Proteins; Animals; Apoptosis; Blood Glucose; Bone Marrow Cells; Bone Marrow Transplantati | 2014 |
SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance.
Topics: Acetone; Animals; Brain Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Female; Glioblasto | 2015 |
Glycation of vitronectin inhibits VEGF-induced angiogenesis by uncoupling VEGF receptor-2-αvβ3 integrin cross-talk.
Topics: Animals; Cell Line; Cell Movement; Cell Proliferation; Diabetes Complications; Diabetes Mellitus, Ex | 2015 |
Decreasing intracellular superoxide corrects defective ischemia-induced new vessel formation in diabetic mice.
Topics: Animals; Bone Marrow Transplantation; Diabetes Mellitus, Experimental; Glucose; Hyperglycemia; Hypox | 2008 |