pyruvaldehyde has been researched along with Idiopathic Parkinson Disease in 13 studies
Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aging is a Parkinson's disease (PD) risk factor." | 2.50 | Aging risk factors and Parkinson's disease: contrasting roles of common dietary constituents. ( Hipkiss, AR, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 11 (84.62) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, J | 1 |
| Tak, S | 1 |
| Jung, HM | 1 |
| Cha, S | 1 |
| Hwang, E | 1 |
| Lee, D | 1 |
| Lee, JH | 1 |
| Ryu, KS | 1 |
| Park, C | 2 |
| Coukos, JS | 1 |
| Lee, CW | 1 |
| Pillai, KS | 1 |
| Shah, H | 1 |
| Moellering, RE | 1 |
| Andreeva, A | 1 |
| Bekkhozhin, Z | 1 |
| Omertassova, N | 1 |
| Baizhumanov, T | 1 |
| Yeltay, G | 1 |
| Akhmetali, M | 1 |
| Toibazar, D | 1 |
| Utepbergenov, D | 1 |
| Matsuda, N | 1 |
| Kimura, M | 1 |
| Queliconi, BB | 1 |
| Kojima, W | 1 |
| Mishima, M | 1 |
| Takagi, K | 1 |
| Koyano, F | 1 |
| Yamano, K | 1 |
| Mizushima, T | 1 |
| Ito, Y | 1 |
| Tanaka, K | 1 |
| Frandsen, JR | 1 |
| Narayanasamy, P | 1 |
| Robertson, DS | 1 |
| König, A | 1 |
| Vicente Miranda, H | 1 |
| Outeiro, TF | 1 |
| Sharma, N | 1 |
| Rao, SP | 1 |
| Kalivendi, SV | 1 |
| Hipkiss, AR | 1 |
| Xie, B | 2 |
| Lin, F | 2 |
| Peng, L | 2 |
| Ullah, K | 2 |
| Wu, H | 1 |
| Qing, H | 2 |
| Deng, Y | 2 |
| Ding, W | 1 |
| Dai, R | 1 |
| Natkańska, U | 1 |
| Skoneczna, A | 1 |
| Sieńko, M | 1 |
| Skoneczny, M | 1 |
| Lee, JY | 1 |
| Song, J | 1 |
| Kwon, K | 1 |
| Jang, S | 1 |
| Kim, C | 1 |
| Baek, K | 1 |
| Kim, J | 1 |
3 reviews available for pyruvaldehyde and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Neuroprotection through flavonoid: Enhancement of the glyoxalase pathway.
Topics: Aging; Alzheimer Disease; Animals; Antioxidants; Autism Spectrum Disorder; Flavonoids; Humans; Lacto | 2018 |
Alpha-Synuclein Glycation and the Action of Anti-Diabetic Agents in Parkinson's Disease.
Topics: alpha-Synuclein; Diabetes Complications; Glucose; Glycation End Products, Advanced; Glycosylation; H | 2018 |
Aging risk factors and Parkinson's disease: contrasting roles of common dietary constituents.
Topics: Aging; Animals; Carnosine; Clinical Trials as Topic; Dietary Carbohydrates; Dietary Supplements; Dou | 2014 |
10 other studies available for pyruvaldehyde and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Kinetic evidence in favor of glyoxalase III and against deglycase activity of DJ-1.
Topics: Aldehyde Oxidoreductases; Humans; Lactic Acid; Parkinson Disease; Protein Deglycase DJ-1; Pyruvaldeh | 2023 |
PARK7 Catalyzes Stereospecific Detoxification of Methylglyoxal Consistent with Glyoxalase and Not Deglycase Function.
Topics: Humans; Lactic Acid; Magnesium Oxide; Parkinson Disease; Protein Deglycase DJ-1; Pyruvaldehyde | 2023 |
The apparent deglycase activity of DJ-1 results from the conversion of free methylglyoxal present in fast equilibrium with hemithioacetals and hemiaminals.
Topics: Humans; Parkinson Disease; Protein Deglycase DJ-1; Pyruvaldehyde; Serum Albumin, Bovine | 2019 |
Parkinson's disease-related DJ-1 functions in thiol quality control against aldehyde attack in vitro.
Topics: Acetylcysteine; Aldehydes; Amino Acid Sequence; beta-Alanine; Coenzyme A; Glutathione; HeLa Cells; H | 2017 |
Proposed biochemistry of Parkinson's and Alzheimer's diseases.
Topics: Aldehydes; Alzheimer Disease; Aspartic Acid; Betaine; Brain; Disease Progression; Humans; Kynurenine | 2017 |
The deglycase activity of DJ-1 mitigates α-synuclein glycation and aggregation in dopaminergic cells: Role of oxidative stress mediated downregulation of DJ-1 in Parkinson's disease.
Topics: 1-Methyl-4-phenylpyridinium; alpha-Synuclein; Animals; Cell Line; Dopaminergic Neurons; Gene Express | 2019 |
Methylglyoxal increases dopamine level and leads to oxidative stress in SH-SY5Y cells.
Topics: Cell Line; Diabetes Mellitus, Type 2; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamin | 2014 |
A newly discovered neurotoxin ADTIQ associated with hyperglycemia and Parkinson's disease.
Topics: alpha-Synuclein; Animals; Brain; Cell Death; Cell Line; Diabetes Mellitus, Experimental; Dopaminergi | 2015 |
The budding yeast orthologue of Parkinson's disease-associated DJ-1 is a multi-stress response protein protecting cells against toxic glycolytic products.
Topics: Acetic Acid; Base Sequence; DNA-Binding Proteins; Ethanol; Heat-Shock Proteins; Humans; Parkinson Di | 2017 |
Human DJ-1 and its homologs are novel glyoxalases.
Topics: Aldehyde Oxidoreductases; Amino Acid Sequence; Animals; Apoptosis; Caenorhabditis elegans; Caenorhab | 2012 |