pyruvaldehyde has been researched along with Fibrosis in 10 studies
Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.
Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Candesartan treatment for 4 weeks significantly reduced these parameters." | 1.39 | Carbonyl stress induces hypertension and cardio-renal vascular injury in Dahl salt-sensitive rats. ( Chen, X; Endo, S; Guo, Q; Hu, C; Ito, S; Jiang, Y; Miyata, T; Mori, T; Nakayama, K; Nakayama, M; Ogawa, S; Ohsaki, Y; Yoneki, Y; Zhu, W, 2013) |
| "Fibrosis is a frequent complication of diabetes mellitus in many organs and tissues but the mechanism of how diabetes-induced glycation of extracellular matrix proteins impacts the formation of fibrotic lesions is not defined." | 1.36 | Methylglyoxal-modified collagen promotes myofibroblast differentiation. ( Birek, J; Chan, M; Laschinger, C; Lee, W; McCulloch, CA; Simmons, CA; Sivagurunathan, K; Talior, I; Won, E; Young, EW; Yuen, A, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 4 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Francisco, FA | 1 |
| Saavedra, LPJ | 1 |
| Ferreira-Junior, MD | 1 |
| Cavalcante, KVN | 1 |
| Moreira, VM | 1 |
| Prates, KV | 1 |
| Borges, SC | 1 |
| Buttow, NC | 1 |
| Ribeiro, TA | 1 |
| Pedrino, GR | 1 |
| Xavier, CH | 1 |
| Matafome, P | 3 |
| de Freitas Mathias, PC | 1 |
| Gomes, RM | 1 |
| Chen, SM | 2 |
| Lin, CE | 2 |
| Chen, HH | 1 |
| Cheng, YF | 1 |
| Cheng, HW | 1 |
| Imai, K | 1 |
| Mojadami, S | 1 |
| Ahangarpour, A | 1 |
| Mard, SA | 1 |
| Khorsandi, L | 1 |
| Lin, PY | 1 |
| Yang, WC | 1 |
| Huang, YS | 1 |
| Lin, TY | 1 |
| Chen, CM | 1 |
| Chen, HS | 1 |
| Lee, JA | 1 |
| Rodrigues, T | 2 |
| Sereno, J | 1 |
| Almeida, J | 1 |
| Castelhano, J | 1 |
| Gamas, L | 1 |
| Neves, C | 1 |
| Gonçalves, S | 1 |
| Carvalho, C | 1 |
| Arslanagic, A | 1 |
| Wilcken, E | 1 |
| Fonseca, R | 1 |
| Simões, I | 1 |
| Conde, SV | 1 |
| Castelo-Branco, M | 1 |
| Seiça, R | 2 |
| Pastino, AK | 1 |
| Greco, TM | 1 |
| Mathias, RA | 1 |
| Cristea, IM | 1 |
| Schwarzbauer, JE | 1 |
| Subramanian, U | 1 |
| Nagarajan, D | 1 |
| Yuen, A | 1 |
| Laschinger, C | 1 |
| Talior, I | 1 |
| Lee, W | 1 |
| Chan, M | 1 |
| Birek, J | 1 |
| Young, EW | 1 |
| Sivagurunathan, K | 1 |
| Won, E | 1 |
| Simmons, CA | 1 |
| McCulloch, CA | 1 |
| Santos-Silva, D | 1 |
| Crisóstomo, J | 1 |
| Rodrigues, L | 1 |
| Sena, CM | 1 |
| Pereira, P | 1 |
| Chen, X | 1 |
| Mori, T | 1 |
| Guo, Q | 1 |
| Hu, C | 1 |
| Ohsaki, Y | 1 |
| Yoneki, Y | 1 |
| Zhu, W | 1 |
| Jiang, Y | 1 |
| Endo, S | 1 |
| Nakayama, K | 1 |
| Ogawa, S | 1 |
| Nakayama, M | 1 |
| Miyata, T | 1 |
| Ito, S | 1 |
10 other studies available for pyruvaldehyde and Fibrosis
| Article | Year |
|---|---|
Early postnatal exposure of rat pups to methylglyoxal induces oxidative stress, inflammation and dysmetabolism at adulthood.
Topics: Animals; Female; Fibrosis; Inflammation; Oxidative Stress; Pyruvaldehyde; Rats; Rats, Wistar | 2022 |
Effect of prednisolone on glyoxalase 1 in an inbred mouse model of aristolochic acid nephropathy using a proteomics method with fluorogenic derivatization-liquid chromatography-tandem mass spectrometry.
Topics: Animals; Aristolochic Acids; Chromatography, High Pressure Liquid; Disease Models, Animal; Female; F | 2020 |
Diabetic nephropathy induced by methylglyoxal: gallic acid regulates kidney microRNAs and glyoxalase1-Nrf2 in male mice.
Topics: Animals; Diabetes Mellitus; Diabetic Nephropathies; Fibrosis; Gallic Acid; Kidney; Male; Mice; Micro | 2023 |
Evaluation of the nephrotoxicity and safety of low-dose aristolochic acid, extending to the use of Xixin (Asurum), by determination of methylglyoxal and d-lactate.
Topics: Animals; Aristolochic Acids; Collagen; Disease Models, Animal; Drugs, Chinese Herbal; Female; Fibros | 2021 |
Methylglyoxal-induced glycation changes adipose tissue vascular architecture, flow and expansion, leading to insulin resistance.
Topics: Adipose Tissue; Animals; Diet, High-Fat; Fasting; Fibrosis; Glycated Hemoglobin; Glycoconjugates; Gl | 2017 |
Stimulatory effects of advanced glycation endproducts (AGEs) on fibronectin matrix assembly.
Topics: Amino Acid Sequence; Animals; Antibodies, Neutralizing; Cattle; Cell Line, Transformed; Extracellula | 2017 |
All-Trans Retinoic Acid supplementation prevents cardiac fibrosis and cytokines induced by Methylglyoxal.
Topics: Animals; Cytokines; Dietary Supplements; Fibrosis; Gene Expression Regulation; Male; Pyruvaldehyde; | 2017 |
Methylglyoxal-modified collagen promotes myofibroblast differentiation.
Topics: Actins; Biomarkers; Cadherins; Cell Differentiation; Cell Movement; Cells, Cultured; Collagen; Dose- | 2010 |
Methylglyoxal causes structural and functional alterations in adipose tissue independently of obesity.
Topics: Adipokines; Adipose Tissue; Animals; Apoptosis; Biomarkers; Cell Hypoxia; Fibrosis; Hyperglycemia; I | 2012 |
Carbonyl stress induces hypertension and cardio-renal vascular injury in Dahl salt-sensitive rats.
Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; B | 2013 |