pyruvaldehyde has been researched along with Fanconi Anemia in 3 studies
Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.
Fanconi Anemia: Congenital disorder affecting all bone marrow elements, resulting in ANEMIA; LEUKOPENIA; and THROMBOPENIA, and associated with cardiac, renal, and limb malformations as well as dermal pigmentary changes. Spontaneous CHROMOSOME BREAKAGE is a feature of this disease along with predisposition to LEUKEMIA. There are at least 7 complementation groups in Fanconi anemia: FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG, and FANCL. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227650, August 20, 2004)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Formaldehyde is an aliphatic monoaldehyde and is a highly reactive environmental human carcinogen." | 1.34 | Cells deficient in the FANC/BRCA pathway are hypersensitive to plasma levels of formaldehyde. ( Arakawa, H; Bishop, DK; Buerstedde, JM; Gillespie, DA; Luke, AM; Nakamura, A; Nakamura, J; Ridpath, JR; Sale, JE; Sonoda, E; Swenberg, JA; Takata, M; Takeda, S; Tano, K; Watanabe, M; Yamazoe, M, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pagano, G | 2 |
| Degan, P | 2 |
| d'Ischia, M | 2 |
| Kelly, FJ | 2 |
| Pallardó, FV | 2 |
| Zatterale, A | 2 |
| Anak, SS | 1 |
| Akisik, EE | 1 |
| Beneduce, G | 1 |
| Calzone, R | 2 |
| De Nicola, E | 1 |
| Dunster, C | 2 |
| Lloret, A | 2 |
| Manini, P | 2 |
| Nobili, B | 1 |
| Saviano, A | 1 |
| Vuttariello, E | 1 |
| Warnau, M | 1 |
| Ridpath, JR | 1 |
| Nakamura, A | 1 |
| Tano, K | 1 |
| Luke, AM | 1 |
| Sonoda, E | 1 |
| Arakawa, H | 1 |
| Buerstedde, JM | 1 |
| Gillespie, DA | 1 |
| Sale, JE | 1 |
| Yamazoe, M | 1 |
| Bishop, DK | 1 |
| Takata, M | 1 |
| Takeda, S | 1 |
| Watanabe, M | 1 |
| Swenberg, JA | 1 |
| Nakamura, J | 1 |
1 review available for pyruvaldehyde and Fanconi Anemia
| Article | Year |
|---|---|
Different patterns of in vivo pro-oxidant states in a set of cancer- or aging-related genetic diseases.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adolescent; Adult; Aged; Ataxia Telangiectasia; Bloom Syndrome; Child; | 2008 |
2 other studies available for pyruvaldehyde and Fanconi Anemia
| Article | Year |
|---|---|
Gender- and age-related distinctions for the in vivo prooxidant state in Fanconi anaemia patients.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adolescent; Adult; Age Factors; Ascorbic Acid; Case-Control Studies; Ch | 2004 |
Cells deficient in the FANC/BRCA pathway are hypersensitive to plasma levels of formaldehyde.
Topics: Acetaldehyde; Acrolein; Aldehydes; Animals; BRCA1 Protein; Cell Cycle; Cell Survival; Chickens; Cros | 2007 |