pyruvaldehyde has been researched along with Encapsulating Peritoneal Sclerosis in 14 studies
Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We prepared peritoneal fibrosis rats by intraperitoneal administration of PD fluids containing MGO for 21 days." | 1.56 | Hypermetabolism of glutathione, glutamate and ornithine via redox imbalance in methylglyoxal-induced peritoneal injury rats. ( Hirahara, I; Jin, D; Kusano, E; Takai, S, 2020) |
| "MGO induced parietal and visceral peritoneal fibrosis in wild-type mice, which was significantly reduced in mice deficient in NLRP3, ASC, and interleukin-1β (IL-1β)." | 1.51 | Crucial Role of NLRP3 Inflammasome in the Development of Peritoneal Dialysis-related Peritoneal Fibrosis. ( Aizawa, E; Akimoto, T; Hishida, E; Ito, H; Kamata, R; Karasawa, T; Kasahara, T; Kimura, H; Komada, T; Morishita, Y; Nagata, D; Takahashi, M; Watanabe, S, 2019) |
| "Sinefungin was shown immunohistochemically to suppress expression of mesenchymal cells and collagen deposition, accompanied by decreased H3K4me1 levels." | 1.48 | Inhibition of the H3K4 methyltransferase SET7/9 ameliorates peritoneal fibrosis. ( Doi, S; Maeda, K; Masaki, T; Nakashima, A; Sasaki, K; Tamura, R; Ueno, T, 2018) |
| "Peritoneal fibrosis was induced by peritoneal injection of methylglyoxal (MGO) in male C57/B6 mice for 3 weeks." | 1.46 | Inhibition of H3K9 methyltransferase G9a ameliorates methylglyoxal-induced peritoneal fibrosis. ( Doi, S; Irifuku, T; Maeda, K; Masaki, T; Nagai, T; Nakashima, A; Ueno, T, 2017) |
| "Peritoneal fibrosis was induced by daily intraperitoneal injection of saline containing 40 mmol/L MGO for 21 days." | 1.43 | Linagliptin Ameliorates Methylglyoxal-Induced Peritoneal Fibrosis in Mice. ( Doi, S; Irifuku, T; Masaki, T; Nagai, T; Nakashima, A; Sasaki, K; Ueno, T, 2016) |
| "At worst, peritoneal injury leads to encapsulating peritoneal sclerosis (EPS), which is a serious complication of PD." | 1.42 | Methylglyoxal Induced Basophilic Spindle Cells with Podoplanin at the Surface of Peritoneum in Rat Peritoneal Dialysis Model. ( Hirahara, I; Imai, T; Kusano, E; Morishita, Y; Muto, S; Nagata, D; Onishi, A; Sato, H, 2015) |
| "Adenine-treated Sprague-Dawley rats were randomly assigned to receive continuous peritoneal injections of PDF with or without MGO for three weeks or were left untreated for the same duration." | 1.40 | Peritoneal fibrosis induced by intraperitoneal methylglyoxal injection: the role of concurrent renal dysfunction. ( Akimoto, T; Hirahara, I; Inoue, M; Kusano, E; Morishita, Y; Nagata, D; Onishi, A, 2014) |
| "We used the rat model of peritoneal fibrosis induced by intraperitoneal injection of methylglyoxal and in vitro mesothelial cell culture to test the effects of CBR ligands, including the type 1 CBR (CB(1)R) antagonist and the type 2 CBR (CB(2)R) agonist." | 1.39 | Cannabinoid receptors as therapeutic targets for dialysis-induced peritoneal fibrosis. ( Chau, YP; Kuo, HY; Lee, HT; Lee, OK; Yang, AH; Yang, CY, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 12 (85.71) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Hirahara, I | 4 |
| Kusano, E | 4 |
| Jin, D | 1 |
| Takai, S | 1 |
| Yoshimine, H | 1 |
| Tanoue, S | 1 |
| Ibi, Y | 1 |
| Minami, M | 1 |
| Nakahara, M | 1 |
| Tokunaga, K | 1 |
| Kanmura, S | 1 |
| Ido, A | 1 |
| Li, D | 1 |
| Lu, Z | 1 |
| Li, X | 1 |
| Xu, Z | 1 |
| Jiang, J | 1 |
| Zheng, Z | 1 |
| Jia, J | 1 |
| Lin, S | 1 |
| Yan, T | 1 |
| Tamura, R | 1 |
| Doi, S | 3 |
| Nakashima, A | 3 |
| Sasaki, K | 2 |
| Maeda, K | 2 |
| Ueno, T | 3 |
| Masaki, T | 3 |
| Iguchi, D | 1 |
| Mizuno, M | 1 |
| Suzuki, Y | 1 |
| Sakata, F | 1 |
| Maruyama, S | 1 |
| Okada, A | 1 |
| Okada, H | 1 |
| Ito, Y | 1 |
| Hishida, E | 1 |
| Ito, H | 1 |
| Komada, T | 1 |
| Karasawa, T | 1 |
| Kimura, H | 1 |
| Watanabe, S | 1 |
| Kamata, R | 1 |
| Aizawa, E | 1 |
| Kasahara, T | 1 |
| Morishita, Y | 3 |
| Akimoto, T | 3 |
| Nagata, D | 4 |
| Takahashi, M | 1 |
| Onishi, A | 3 |
| Inoue, M | 1 |
| Sato, H | 1 |
| Imai, T | 1 |
| Muto, S | 2 |
| Urabe, M | 1 |
| Ozawa, K | 1 |
| Fan, YP | 1 |
| Hsia, CC | 1 |
| Tseng, KW | 1 |
| Liao, CK | 1 |
| Fu, TW | 1 |
| Ko, TL | 1 |
| Chiu, MM | 1 |
| Shih, YH | 1 |
| Huang, PY | 1 |
| Chiang, YC | 1 |
| Yang, CC | 1 |
| Fu, YS | 1 |
| Nagai, T | 2 |
| Irifuku, T | 2 |
| Kitamura, M | 1 |
| Nishino, T | 1 |
| Obata, Y | 1 |
| Furusu, A | 1 |
| Hishikawa, Y | 1 |
| Koji, T | 1 |
| Kohno, S | 1 |
| Yang, CY | 1 |
| Chau, YP | 1 |
| Lee, HT | 1 |
| Kuo, HY | 1 |
| Lee, OK | 1 |
| Yang, AH | 1 |
14 other studies available for pyruvaldehyde and Encapsulating Peritoneal Sclerosis
| Article | Year |
|---|---|
Hypermetabolism of glutathione, glutamate and ornithine via redox imbalance in methylglyoxal-induced peritoneal injury rats.
Topics: Animals; Disease Models, Animal; Glutamic Acid; Glutathione; Male; Ornithine; Oxidation-Reduction; P | 2020 |
Hepatocyte growth factor ameliorates methylglyoxal-induced peritoneal inflammation and fibrosis in mouse model.
Topics: Actins; Animals; Collagen Type I; Collagen Type III; Disease Models, Animal; Gene Expression; Hepato | 2021 |
Human umbilical cord mesenchymal stem cells facilitate the up-regulation of miR-153-3p, whereby attenuating MGO-induced peritoneal fibrosis in rats.
Topics: 3' Untranslated Regions; Animals; Cells, Cultured; Culture Media, Conditioned; Epithelial-Mesenchyma | 2018 |
Inhibition of the H3K4 methyltransferase SET7/9 ameliorates peritoneal fibrosis.
Topics: Adenosine; Animals; Cells, Cultured; Collagen Type I; Dialysis Solutions; Epithelium; Gene Expressio | 2018 |
Anti-C5a complementary peptide mitigates zymosan-induced severe peritonitis with fibrotic encapsulation in rats pretreated with methylglyoxal.
Topics: Animals; Complement Activation; Complement C5a; Complement Inactivating Agents; Disease Models, Anim | 2018 |
Crucial Role of NLRP3 Inflammasome in the Development of Peritoneal Dialysis-related Peritoneal Fibrosis.
Topics: Animals; CARD Signaling Adaptor Proteins; Disease Models, Animal; Endothelial Cells; Female; Human U | 2019 |
Peritoneal fibrosis induced by intraperitoneal methylglyoxal injection: the role of concurrent renal dysfunction.
Topics: Adenine; Animals; Body Weight; Kidney Function Tests; Matrix Metalloproteinase 2; Peritoneal Fibrosi | 2014 |
Methylglyoxal Induced Basophilic Spindle Cells with Podoplanin at the Surface of Peritoneum in Rat Peritoneal Dialysis Model.
Topics: Animals; Basophils; Disease Models, Animal; Epithelial Cells; Epithelial-Mesenchymal Transition; Hum | 2015 |
Attenuation of methylglyoxal-induced peritoneal fibrosis: immunomodulation by interleukin-10.
Topics: Adenoviridae; Animals; Body Weight; Disease Models, Animal; Genetic Therapy; Immunomodulation; Inter | 2015 |
The Therapeutic Potential of Human Umbilical Mesenchymal Stem Cells From Wharton's Jelly in the Treatment of Rat Peritoneal Dialysis-Induced Fibrosis.
Topics: Actins; Animals; Biomarkers; Cell Death; Culture Media; Disease Models, Animal; Epithelial Cells; Fi | 2016 |
Linagliptin Ameliorates Methylglyoxal-Induced Peritoneal Fibrosis in Mice.
Topics: Animals; Biomarkers; Dipeptidyl-Peptidase IV Inhibitors; Glucagon-Like Peptide 1; Injections, Intrap | 2016 |
Inhibition of H3K9 methyltransferase G9a ameliorates methylglyoxal-induced peritoneal fibrosis.
Topics: Animals; Azepines; Case-Control Studies; Cells, Cultured; DNA Methylation; Gene Expression Regulatio | 2017 |
Epigallocatechin gallate suppresses peritoneal fibrosis in mice.
Topics: Animals; Catechin; Chemokine CCL2; Dialysis Solutions; Inflammation; Male; Mice; Mice, Inbred C57BL; | 2012 |
Cannabinoid receptors as therapeutic targets for dialysis-induced peritoneal fibrosis.
Topics: Animals; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cell Line; Drug Evaluation | 2013 |