pyruvaldehyde has been researched along with Diabetes Mellitus, Type 1 in 38 studies
Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.
Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We measured concentrations of the glycoxidation product Nepsilon-(carboxymethyl)lysine and two non-oxidation-dependent advanced glycation end-products (methylglyoxal-derived and 3-deoxyglucosone-derived) in CD45RA+ T-cells from 21 Type I (insulin-dependent) diabetic patients with and without diabetic retinopathy and from age-matched nondiabetic control subjects." | 7.70 | Diabetic retinopathy risk correlates with intracellular concentrations of the glycoxidation product Nepsilon-(carboxymethyl) lysine independently of glycohaemoglobin concentrations. ( Bretzel, RG; Brownlee, M; Hammes, HP; Lin, J; Schleicher, E, 1999) |
| "We measured concentrations of the glycoxidation product Nepsilon-(carboxymethyl)lysine and two non-oxidation-dependent advanced glycation end-products (methylglyoxal-derived and 3-deoxyglucosone-derived) in CD45RA+ T-cells from 21 Type I (insulin-dependent) diabetic patients with and without diabetic retinopathy and from age-matched nondiabetic control subjects." | 3.70 | Diabetic retinopathy risk correlates with intracellular concentrations of the glycoxidation product Nepsilon-(carboxymethyl) lysine independently of glycohaemoglobin concentrations. ( Bretzel, RG; Brownlee, M; Hammes, HP; Lin, J; Schleicher, E, 1999) |
| "Chronic hyperglycemia is known to increase tissue glycation and diabetic complications, but controversy exists regarding the independent role of increased postprandial glucose excursions." | 2.70 | alpha-Dicarbonyls increase in the postprandial period and reflect the degree of hyperglycemia. ( Beisswenger, PJ; Howell, SK; O'Dell, RM; Szwergold, BS; Touchette, AD; Wood, ME, 2001) |
| "Progression to type 1 diabetes has emerged as a complex process with metabolic alterations proposed to be a significant driver of disease." | 1.91 | Methylglyoxal products in pre-symptomatic type 1 diabetes. ( Achenbach, P; Hernandez-Castillo, C; Roep, BO; Shuck, SC; Termini, JS; Weiss, A; Winkler, C; Ziegler, AG, 2023) |
| "Coronary atherosclerosis was assessed by computed tomography coronary angiography or intravascular ultrasound." | 1.62 | Autoantibodies Against Methylglyoxal-Modified Apolipoprotein B100 and ApoB100 Peptide Are Associated With Less Coronary Artery Atherosclerosis and Retinopathy in Long-Term Type 1 Diabetes. ( Bech Holte, K; Bengtsson, E; Hanssen, KF; Julsrud Berg, T; Nilsson, J; Svanteson, M; Sveen, KA, 2021) |
| "We studied THP in relation to type 1 diabetes, endothelial dysfunction, low-grade inflammation, vascular complications and atherosclerosis." | 1.39 | The methylglyoxal-derived AGE tetrahydropyrimidine is increased in plasma of individuals with type 1 diabetes mellitus and in atherosclerotic lesions and is associated with sVCAM-1. ( Colhoun, HM; Hanssen, NM; Niessen, HW; Parving, HH; Rossing, P; Schalkwijk, CG; Schram, MT; Stehouwer, CD; Tarnow, L; van Eupen, MG, 2013) |
| "In our patients with type 1 diabetes, serum levels of hydroimidazolone were found to be associated with retinopathy." | 1.35 | Increased retinopathy occurrence in type 1 diabetes patients with increased serum levels of the advanced glycation endproduct hydroimidazolone. ( Agardh, CD; Agardh, E; Berg, JP; Fosmark, DS; Hanssen, KF; Jensen, AB; Sandvik, L, 2009) |
| "To assess the role of dAGE on type 1 diabetes, NOD mice were exposed to a high-AGE diet (H-AGE) and to a nutritionally similar diet with approximate fivefold-lower levels of N(epsilon)-carboxymethyllysine (CML) and methylglyoxal-derivatives (MG) (L-AGE)." | 1.32 | Fetal or neonatal low-glycotoxin environment prevents autoimmune diabetes in NOD mice. ( Hattori, M; He, C; McEvoy, R; Peppa, M; Vlassara, H; Zheng, F, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (15.79) | 18.2507 |
| 2000's | 7 (18.42) | 29.6817 |
| 2010's | 21 (55.26) | 24.3611 |
| 2020's | 4 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Darenskaya, MA | 1 |
| Chugunova, EV | 1 |
| Kolesnikov, SI | 1 |
| Grebenkina, LA | 1 |
| Semenova, NV | 1 |
| Nikitina, OA | 1 |
| Kolesnikova, LI | 1 |
| Shuck, SC | 1 |
| Achenbach, P | 1 |
| Roep, BO | 1 |
| Termini, JS | 1 |
| Hernandez-Castillo, C | 1 |
| Winkler, C | 1 |
| Weiss, A | 1 |
| Ziegler, AG | 1 |
| Atawia, RT | 1 |
| Batori, RK | 1 |
| Jordan, CR | 1 |
| Kennard, S | 1 |
| Antonova, G | 1 |
| Bruder-Nascimento, T | 1 |
| Mehta, V | 1 |
| Saeed, MI | 1 |
| Patel, VS | 1 |
| Fukai, T | 1 |
| Ushio-Fukai, M | 1 |
| Huo, Y | 1 |
| Fulton, DJR | 1 |
| Belin de Chantemèle, EJ | 1 |
| Nuti, F | 1 |
| Gallo, A | 1 |
| Real-Fernandez, F | 1 |
| Rentier, C | 1 |
| Rossi, G | 1 |
| Piarulli, F | 1 |
| Traldi, P | 1 |
| Carganico, S | 1 |
| Rovero, P | 1 |
| Lapolla, A | 1 |
| Papini, AM | 1 |
| Sveen, KA | 2 |
| Bech Holte, K | 1 |
| Svanteson, M | 1 |
| Hanssen, KF | 3 |
| Nilsson, J | 1 |
| Bengtsson, E | 1 |
| Julsrud Berg, T | 1 |
| Groener, JB | 1 |
| Oikonomou, D | 1 |
| Cheko, R | 1 |
| Kender, Z | 1 |
| Zemva, J | 1 |
| Kihm, L | 1 |
| Muckenthaler, M | 1 |
| Peters, V | 1 |
| Fleming, T | 2 |
| Kopf, S | 1 |
| Nawroth, PP | 2 |
| Hanssen, NMJ | 1 |
| Scheijen, JLJM | 1 |
| Jorsal, A | 1 |
| Parving, HH | 2 |
| Tarnow, L | 2 |
| Rossing, P | 2 |
| Stehouwer, CDA | 1 |
| Schalkwijk, CG | 2 |
| Wang, B | 3 |
| Yee Aw, T | 1 |
| Stokes, KY | 2 |
| Cheng, RX | 1 |
| Feng, Y | 1 |
| Liu, D | 1 |
| Wang, ZH | 1 |
| Zhang, JT | 1 |
| Chen, LH | 1 |
| Su, CJ | 1 |
| Huang, Y | 1 |
| Ji, RR | 1 |
| Hu, J | 1 |
| Liu, T | 1 |
| van Eupen, MG | 1 |
| Schram, MT | 1 |
| Colhoun, HM | 1 |
| Hanssen, NM | 1 |
| Niessen, HW | 1 |
| Stehouwer, CD | 1 |
| Lupachyk, S | 1 |
| Watcho, P | 1 |
| Shevalye, H | 1 |
| Vareniuk, I | 1 |
| Obrosov, A | 1 |
| Obrosova, IG | 1 |
| Yorek, MA | 1 |
| Karimé, B | 1 |
| Jørum, E | 1 |
| Mellgren, SI | 1 |
| Fagerland, MW | 1 |
| Monnier, VM | 3 |
| Dahl-Jørgensen, K | 1 |
| Vulesevic, B | 1 |
| McNeill, B | 1 |
| Geoffrion, M | 1 |
| Kuraitis, D | 1 |
| McBane, JE | 1 |
| Lochhead, M | 1 |
| Vanderhyden, BC | 1 |
| Korbutt, GS | 1 |
| Milne, RW | 1 |
| Suuronen, EJ | 1 |
| Pun, PB | 1 |
| Logan, A | 1 |
| Darley-Usmar, V | 1 |
| Chacko, B | 1 |
| Johnson, MS | 1 |
| Huang, GW | 1 |
| Rogatti, S | 1 |
| Prime, TA | 1 |
| Methner, C | 1 |
| Krieg, T | 1 |
| Fearnley, IM | 1 |
| Larsen, L | 1 |
| Larsen, DS | 1 |
| Menger, KE | 1 |
| Collins, Y | 1 |
| James, AM | 1 |
| Kumar, GD | 1 |
| Hartley, RC | 1 |
| Smith, RA | 1 |
| Murphy, MP | 1 |
| Ahmad, S | 1 |
| Shahab, U | 1 |
| Habib, S | 1 |
| Salman Khan, M | 1 |
| Alam, K | 1 |
| Ali, A | 1 |
| Genuth, S | 2 |
| Sun, W | 2 |
| Cleary, P | 1 |
| Gao, X | 2 |
| Sell, DR | 2 |
| Lachin, J | 1 |
| Fang, L | 1 |
| Li, X | 1 |
| Zhong, Y | 1 |
| Yu, J | 1 |
| Yu, L | 1 |
| Dai, H | 1 |
| Yan, M | 1 |
| Cleary, PA | 1 |
| Lachin, JM | 1 |
| Aw, TY | 1 |
| Alomar, F | 1 |
| Singh, J | 1 |
| Jang, HS | 1 |
| Rozanzki, GJ | 1 |
| Shao, CH | 1 |
| Padanilam, BJ | 1 |
| Mayhan, WG | 1 |
| Bidasee, KR | 1 |
| Fosmark, DS | 1 |
| Berg, JP | 1 |
| Jensen, AB | 1 |
| Sandvik, L | 1 |
| Agardh, E | 1 |
| Agardh, CD | 1 |
| Mericq, V | 1 |
| Piccardo, C | 1 |
| Cai, W | 1 |
| Chen, X | 1 |
| Zhu, L | 1 |
| Striker, GE | 1 |
| Vlassara, H | 2 |
| Uribarri, J | 1 |
| Sakhi, AK | 1 |
| Berg, TJ | 1 |
| Turk, Z | 2 |
| Cavlović-Naglić, M | 1 |
| Turk, N | 1 |
| Cuny, J | 1 |
| Nawroth, G | 1 |
| Djuric, Z | 1 |
| Humpert, PM | 1 |
| Zeier, M | 1 |
| Bierhaus, A | 1 |
| Siewiera, K | 1 |
| Labieniec-Watala, M | 1 |
| Beisswenger, PJ | 2 |
| Howell, SK | 2 |
| Smith, K | 1 |
| Szwergold, BS | 2 |
| Peppa, M | 1 |
| He, C | 1 |
| Hattori, M | 1 |
| McEvoy, R | 1 |
| Zheng, F | 1 |
| Nemet, I | 1 |
| Duvnjak, L | 1 |
| Car, N | 1 |
| Varga-Defterdarović, L | 1 |
| Nicolay, JP | 1 |
| Schneider, J | 1 |
| Niemoeller, OM | 1 |
| Artunc, F | 1 |
| Portero-Otin, M | 1 |
| Haik, G | 1 |
| Thornalley, PJ | 4 |
| Schleicher, E | 2 |
| Wieder, T | 1 |
| Lang, F | 1 |
| Han, Y | 1 |
| Randell, E | 1 |
| Vasdev, S | 1 |
| Gill, V | 1 |
| Gadag, V | 1 |
| Newhook, LA | 1 |
| Grant, M | 1 |
| Hagerty, D | 1 |
| McLellan, AC | 3 |
| Benn, J | 2 |
| Sonksen, PH | 2 |
| Piskorska, D | 1 |
| Kopieczna-Grzebieniak, E | 1 |
| Degenhardt, TP | 1 |
| Thorpe, SR | 1 |
| Baynes, JW | 1 |
| Hammes, HP | 1 |
| Brownlee, M | 1 |
| Lin, J | 1 |
| Bretzel, RG | 1 |
| O'Dell, RM | 1 |
| Wood, ME | 1 |
| Touchette, AD | 1 |
| Phillips, SA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Diabetes Control and Complications Trial (DCCT)[NCT00360815] | 1,441 participants | Interventional | 1983-08-31 | Completed | |||
| Epidemiology of Diabetes Interventions and Complications (EDIC)[NCT00360893] | 1,441 participants (Actual) | Observational | 1994-04-30 | Active, not recruiting | |||
| Effects of Glycooxidative Stress on Human Aging- Study #3[NCT01363141] | 383 participants (Actual) | Interventional | 2010-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for pyruvaldehyde and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Methylglyoxal and Advanced Glycation End Products in Patients with Diabetes - What We Know so Far and the Missing Links.
Topics: Diabetes Complications; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glycation End Products | 2019 |
[Participation of glyoxalases and methylglyoxal in diabetic complication development].
Topics: Diabetes Mellitus, Type 1; Humans; Hyperglycemia; Lactoylglutathione Lyase; Pyruvaldehyde | 1998 |
2 trials available for pyruvaldehyde and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Skin collagen advanced glycation endproducts (AGEs) and the long-term progression of sub-clinical cardiovascular disease in type 1 diabetes.
Topics: Adult; Arginine; Asymptomatic Diseases; Biomarkers; Biopsy; Cardiovascular Diseases; Carotid Artery | 2015 |
Skin collagen advanced glycation endproducts (AGEs) and the long-term progression of sub-clinical cardiovascular disease in type 1 diabetes.
Topics: Adult; Arginine; Asymptomatic Diseases; Biomarkers; Biopsy; Cardiovascular Diseases; Carotid Artery | 2015 |
Skin collagen advanced glycation endproducts (AGEs) and the long-term progression of sub-clinical cardiovascular disease in type 1 diabetes.
Topics: Adult; Arginine; Asymptomatic Diseases; Biomarkers; Biopsy; Cardiovascular Diseases; Carotid Artery | 2015 |
Skin collagen advanced glycation endproducts (AGEs) and the long-term progression of sub-clinical cardiovascular disease in type 1 diabetes.
Topics: Adult; Arginine; Asymptomatic Diseases; Biomarkers; Biopsy; Cardiovascular Diseases; Carotid Artery | 2015 |
alpha-Dicarbonyls increase in the postprandial period and reflect the degree of hyperglycemia.
Topics: Adolescent; Adult; Aged; Biomarkers; Blood Glucose; Cross-Over Studies; Deoxyglucose; Diabetes Melli | 2001 |
34 other studies available for pyruvaldehyde and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Content of Carbonyl Compounds and Parameters of Glutathione Metabolism in Men with Type 1 Diabetes Mellitus at Preclinical Stages of Diabetic Nephropathy.
Topics: Adolescent; Adult; Albuminuria; Asymptomatic Diseases; Case-Control Studies; Diabetes Mellitus, Type | 2021 |
Methylglyoxal products in pre-symptomatic type 1 diabetes.
Topics: Biomarkers; Diabetes Mellitus, Type 1; Dietary Supplements; Glycation End Products, Advanced; Humans | 2023 |
Type 1 Diabetes Impairs Endothelium-Dependent Relaxation Via Increasing Endothelial Cell Glycolysis Through Advanced Glycation End Products, PFKFB3, and Nox1-Mediated Mechanisms.
Topics: Animals; Diabetes Mellitus, Type 1; Endothelial Cells; Endothelium; Glycolysis; Mice; Pyruvaldehyde | 2023 |
Study of Aberrant Modifications in Peptides as a Test Bench to Investigate the Immunological Response to Non-Enzymatic Glycation.
Topics: Diabetes Mellitus, Type 1; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; Imidazo | 2019 |
Autoantibodies Against Methylglyoxal-Modified Apolipoprotein B100 and ApoB100 Peptide Are Associated With Less Coronary Artery Atherosclerosis and Retinopathy in Long-Term Type 1 Diabetes.
Topics: Apolipoprotein B-100; Atherosclerosis; Autoantibodies; Coronary Artery Disease; Diabetes Mellitus, T | 2021 |
Higher Plasma Methylglyoxal Levels Are Associated With Incident Cardiovascular Disease in Individuals With Type 1 Diabetes: A 12-Year Follow-up Study.
Topics: Adult; Cardiovascular Diseases; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Follow-Up | 2017 |
N-acetylcysteine attenuates systemic platelet activation and cerebral vessel thrombosis in diabetes.
Topics: Acetylcysteine; Animals; Blood Platelets; Brain; Diabetes Mellitus, Type 1; Male; Mice, Inbred C57BL | 2018 |
The role of Na
Topics: Animals; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Disease Models, Animal; Humans; Male; Mic | 2019 |
The methylglyoxal-derived AGE tetrahydropyrimidine is increased in plasma of individuals with type 1 diabetes mellitus and in atherosclerotic lesions and is associated with sVCAM-1.
Topics: Adult; Atherosclerosis; Diabetes Mellitus, Type 1; Enzyme-Linked Immunosorbent Assay; Female; Glycat | 2013 |
Na+/H+ exchanger 1 inhibition reverses manifestation of peripheral diabetic neuropathy in type 1 diabetic rats.
Topics: Aldehydes; Animals; Arterioles; Behavior, Animal; Blood Glucose; Blotting, Western; Body Weight; Dia | 2013 |
Small- and large-fiber neuropathy after 40 years of type 1 diabetes: associations with glycemic control and advanced protein glycation: the Oslo Study.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Follow- | 2013 |
Glyoxalase-1 overexpression in bone marrow cells reverses defective neovascularization in STZ-induced diabetic mice.
Topics: Angiogenic Proteins; Animals; Apoptosis; Blood Glucose; Bone Marrow Cells; Bone Marrow Transplantati | 2014 |
A mitochondria-targeted mass spectrometry probe to detect glyoxals: implications for diabetes.
Topics: Animals; Cattle; Cell Line; Chromatography, Liquid; Diabetes Mellitus, Type 1; Disease Models, Anima | 2014 |
Glycoxidative damage to human DNA: Neo-antigenic epitopes on DNA molecule could be a possible reason for autoimmune response in type 1 diabetes.
Topics: Autoimmunity; Deoxyguanosine; Diabetes Mellitus, Type 1; DNA; DNA Damage; Epitopes; Glycation End Pr | 2014 |
Skin advanced glycation end products glucosepane and methylglyoxal hydroimidazolone are independently associated with long-term microvascular complication progression of type 1 diabetes.
Topics: Adult; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopath | 2015 |
Autophagy protects human brain microvascular endothelial cells against methylglyoxal-induced injuries, reproducible in a cerebral ischemic model in diabetic rats.
Topics: Animals; Autophagy; Blood-Brain Barrier; Brain Ischemia; Capillaries; Cell Line; Cell Survival; Diab | 2015 |
The protection conferred against ischemia-reperfusion injury in the diabetic brain by N-acetylcysteine is associated with decreased dicarbonyl stress.
Topics: Acetylcysteine; Animals; Antioxidants; Blood-Brain Barrier; Brain; Cerebral Infarction; Diabetes Mel | 2016 |
Smooth muscle-generated methylglyoxal impairs endothelial cell-mediated vasodilatation of cerebral microvessels in type 1 diabetic rats.
Topics: Animals; Arterioles; Cerebrovascular Circulation; Diabetes Mellitus, Experimental; Diabetes Mellitus | 2016 |
Increased retinopathy occurrence in type 1 diabetes patients with increased serum levels of the advanced glycation endproduct hydroimidazolone.
Topics: Adolescent; Adult; Aged; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Diabetic Retinopathy; F | 2009 |
Maternally transmitted and food-derived glycotoxins: a factor preconditioning the young to diabetes?
Topics: Adiponectin; Adolescent; Adult; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glycat | 2010 |
Reduced glutathione concentrations are not decreased in red blood cells of patients with long term type 1-diabetes.
Topics: Adult; Diabetes Mellitus, Type 1; Erythrocytes; Female; Glutathione; Humans; Male; Pyruvaldehyde; Ti | 2011 |
Relationship of methylglyoxal-adduct biogenesis to LDL and triglyceride levels in diabetics.
Topics: Adult; Aged; Aged, 80 and over; Cholesterol, LDL; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diab | 2011 |
Is diabetes an acquired disorder of reactive glucose metabolites and their intermediates?
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Erythrocytes; Fema | 2012 |
Ambiguous effect of dendrimer PAMAM G3 on rat heart respiration in a model of an experimental diabetes - Objective causes of laboratory misfortune or unpredictable G3 activity?
Topics: Animals; Cell Respiration; Cytoprotection; Dendrimers; Diabetes Mellitus, Experimental; Diabetes Mel | 2012 |
Glyceraldehyde-3-phosphate dehydrogenase activity as an independent modifier of methylglyoxal levels in diabetes.
Topics: Adult; Cells, Cultured; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Ery | 2003 |
Fetal or neonatal low-glycotoxin environment prevents autoimmune diabetes in NOD mice.
Topics: Administration, Oral; Aging; Albuminuria; Animals; Animals, Newborn; Blood Glucose; Creatinine; Cros | 2003 |
Humoral methylglyoxal level reflects glycemic fluctuation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Glucose; Case-Control Studies; Chromatography, Hig | 2005 |
Stimulation of suicidal erythrocyte death by methylglyoxal.
Topics: Annexin A5; Blood Glucose; Cell Death; Diabetes Mellitus, Type 1; Erythrocytes; Female; Flow Cytomet | 2006 |
Plasma methylglyoxal and glyoxal are elevated and related to early membrane alteration in young, complication-free patients with Type 1 diabetes.
Topics: Adolescent; Adult; Cell Membrane; Child; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Disease P | 2007 |
Glyoxalase system in clinical diabetes mellitus and correlation with diabetic complications.
Topics: Adult; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathi | 1994 |
Modification of the glyoxalase system in clinical diabetes mellitus.
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Humans; Lactoylglutathione | 1993 |
Chemical modification of proteins by methylglyoxal.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Animals; Aorta; Arginine; Child; Collagen; Crysta | 1998 |
Diabetic retinopathy risk correlates with intracellular concentrations of the glycoxidation product Nepsilon-(carboxymethyl) lysine independently of glycohaemoglobin concentrations.
Topics: Adult; Deoxyglucose; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Female; Glycated Hemoglobin; G | 1999 |
The assay of methylglyoxal in biological systems by derivatization with 1,2-diamino-4,5-dimethoxybenzene.
Topics: Calibration; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 1; Diabetes Mellitus, Typ | 1992 |