pyruvaldehyde has been researched along with Complications of Diabetes Mellitus in 57 studies
Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diabetic complications are major health problems worldwide, with the cost of caring for diabetes rising to US$245 billion in 2012 in the U." | 2.50 | Methylglyoxal in diabetes: link to treatment, glycaemic control and biomarkers of complications. ( Beisswenger, PJ, 2014) |
| "Moreover, a new hypothesis on cancer has been proposed, suggesting that excessive ATP formation in cells may lead to malignancy." | 2.44 | A brief critical overview of the biological effects of methylglyoxal and further evaluation of a methylglyoxal-based anticancer formulation in treating cancer patients. ( Das, S; Ray, M; Ray, S; Talukdar, D, 2008) |
| "Atherosclerosis is a major global cause of morbidity and mortality, and diabetes patients are at increased risk of coronary heart disease development." | 2.44 | Advanced glycation: a novel outlook on atherosclerosis. ( Knight, SC; Price, CL, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (8.77) | 18.2507 |
| 2000's | 20 (35.09) | 29.6817 |
| 2010's | 24 (42.11) | 24.3611 |
| 2020's | 8 (14.04) | 2.80 |
| Authors | Studies |
|---|---|
| Pignalosa, FC | 1 |
| Desiderio, A | 1 |
| Mirra, P | 1 |
| Nigro, C | 1 |
| Perruolo, G | 1 |
| Ulianich, L | 1 |
| Formisano, P | 1 |
| Beguinot, F | 1 |
| Miele, C | 1 |
| Napoli, R | 1 |
| Fiory, F | 1 |
| Cortizo, FG | 1 |
| Pfaff, D | 2 |
| Wirth, A | 1 |
| Schlotterer, A | 1 |
| Medert, R | 1 |
| Morgenstern, J | 1 |
| Weber, T | 1 |
| Hammes, HP | 1 |
| Fleming, T | 4 |
| Nawroth, PP | 4 |
| Freichel, M | 1 |
| Teleman, AA | 1 |
| Rabbani, N | 2 |
| Wang, W | 1 |
| Zhu, Y | 1 |
| Sang, S | 2 |
| Komati, A | 1 |
| Anand, A | 1 |
| Shaik, H | 1 |
| Mudiam, MKR | 1 |
| Suresh Babu, K | 1 |
| Tiwari, AK | 1 |
| Fang, X | 1 |
| Liu, L | 1 |
| Zhou, S | 1 |
| Zhu, M | 1 |
| Wang, B | 1 |
| Tan, SM | 1 |
| Lindblom, RSJ | 1 |
| Ziemann, M | 1 |
| Laskowski, A | 1 |
| Granata, C | 1 |
| Snelson, M | 1 |
| Thallas-Bonke, V | 1 |
| El-Osta, A | 1 |
| Baeza-Garza, CD | 1 |
| Caldwell, ST | 1 |
| Hartley, RC | 1 |
| Krieg, T | 1 |
| Cooper, ME | 1 |
| Murphy, MP | 1 |
| Coughlan, MT | 1 |
| Ahmad, S | 1 |
| Khan, MS | 1 |
| Alouffi, S | 1 |
| Khan, S | 1 |
| Khan, M | 1 |
| Akashah, R | 1 |
| Faisal, M | 1 |
| Shahab, U | 1 |
| Groener, JB | 2 |
| Oikonomou, D | 1 |
| Cheko, R | 1 |
| Kender, Z | 1 |
| Zemva, J | 2 |
| Kihm, L | 1 |
| Muckenthaler, M | 1 |
| Peters, V | 1 |
| Kopf, S | 1 |
| Moghadam, SS | 1 |
| Oryan, A | 1 |
| Kurganov, BI | 1 |
| Tamaddon, AM | 1 |
| Alavianehr, MM | 1 |
| Moosavi-Movahedi, AA | 1 |
| Yousefi, R | 1 |
| Aikawa, T | 1 |
| Matsubara, H | 1 |
| Ugaji, S | 1 |
| Shirakawa, J | 1 |
| Nagai, R | 1 |
| Munesue, S | 1 |
| Harashima, A | 1 |
| Yamamoto, Y | 1 |
| Tsuchiya, H | 1 |
| Szwergold, B | 1 |
| Herzig, S | 1 |
| Teleman, A | 1 |
| Tyedmers, J | 1 |
| König, A | 1 |
| Vicente Miranda, H | 1 |
| Outeiro, TF | 1 |
| Li, CT | 1 |
| How, SC | 1 |
| Chen, ME | 1 |
| Lo, CH | 1 |
| Chun, MC | 1 |
| Chang, CK | 1 |
| Chen, WA | 1 |
| Wu, JW | 1 |
| Wang, SS | 1 |
| Sankaralingam, S | 1 |
| Ibrahim, A | 1 |
| Rahman, MDM | 1 |
| Eid, AH | 1 |
| Munusamy, S | 1 |
| Bellier, J | 1 |
| Nokin, MJ | 1 |
| Lardé, E | 1 |
| Karoyan, P | 1 |
| Peulen, O | 1 |
| Castronovo, V | 1 |
| Bellahcène, A | 1 |
| Wang, H | 1 |
| Xu, Y | 1 |
| Rao, L | 1 |
| Yang, C | 1 |
| Yuan, H | 1 |
| Gao, T | 1 |
| Chen, X | 1 |
| Sun, H | 1 |
| Xian, M | 1 |
| Liu, C | 2 |
| Li, W | 1 |
| Xu, H | 2 |
| Hu, Y | 1 |
| He, P | 1 |
| Ni, Z | 1 |
| Zhang, Z | 1 |
| Dai, H | 1 |
| Beisswenger, PJ | 2 |
| Chakraborty, S | 1 |
| Karmakar, K | 1 |
| Chakravortty, D | 1 |
| Maessen, DE | 1 |
| Stehouwer, CD | 1 |
| Schalkwijk, CG | 1 |
| Wang, L | 2 |
| Zhang, X | 1 |
| Pang, N | 1 |
| Xiao, L | 1 |
| Li, Y | 1 |
| Chen, N | 1 |
| Ren, M | 1 |
| Deng, X | 1 |
| Wu, J | 1 |
| Stratmann, B | 2 |
| Engelbrecht, B | 2 |
| Espelage, BC | 1 |
| Klusmeier, N | 1 |
| Tiemann, J | 1 |
| Gawlowski, T | 2 |
| Mattern, Y | 1 |
| Eisenacher, M | 1 |
| Meyer, HE | 1 |
| Thornalley, PJ | 3 |
| Tschoepe, D | 2 |
| Poschmann, G | 1 |
| Stühler, K | 1 |
| Vander Jagt, DL | 5 |
| Talukdar, D | 1 |
| Ray, S | 1 |
| Ray, M | 1 |
| Das, S | 1 |
| Takahashi, K | 1 |
| Tatsunami, R | 1 |
| Tampo, Y | 1 |
| Lu, MP | 1 |
| Wang, R | 1 |
| Song, X | 1 |
| Chibbar, R | 1 |
| Wang, X | 1 |
| Wu, L | 1 |
| Meng, QH | 1 |
| Stork, I | 1 |
| Brodehl, A | 1 |
| Niehaus, K | 1 |
| Körfer, R | 1 |
| Milting, H | 1 |
| Turk, Z | 1 |
| Thangarajah, H | 1 |
| Yao, D | 1 |
| Chang, EI | 1 |
| Shi, Y | 1 |
| Jazayeri, L | 1 |
| Vial, IN | 1 |
| Galiano, RD | 1 |
| Du, XL | 1 |
| Grogan, R | 1 |
| Galvez, MG | 1 |
| Januszyk, M | 1 |
| Brownlee, M | 1 |
| Gurtner, GC | 1 |
| Lv, L | 1 |
| Shao, X | 1 |
| Huang, D | 1 |
| Ho, CT | 1 |
| Ganini, D | 1 |
| Christoff, M | 1 |
| Ehrenshaft, M | 1 |
| Kadiiska, MB | 1 |
| Mason, RP | 1 |
| Bechara, EJ | 1 |
| Engelbertsen, D | 1 |
| Anand, DV | 1 |
| Fredrikson, GN | 1 |
| Hopkins, D | 1 |
| Corder, R | 1 |
| Shah, PK | 1 |
| Lahiri, A | 1 |
| Nilsson, J | 1 |
| Bengtsson, E | 1 |
| Maher, P | 1 |
| Dargusch, R | 1 |
| Ehren, JL | 1 |
| Okada, S | 1 |
| Sharma, K | 1 |
| Schubert, D | 1 |
| Babizhayev, MA | 1 |
| Deyev, AI | 1 |
| Savel'yeva, EL | 1 |
| Lankin, VZ | 1 |
| Yegorov, YE | 1 |
| Kimura, R | 1 |
| Okouchi, M | 1 |
| Kato, T | 1 |
| Imaeda, K | 1 |
| Okayama, N | 1 |
| Asai, K | 1 |
| Joh, T | 1 |
| Vlassara, H | 2 |
| Cai, W | 2 |
| Crandall, J | 1 |
| Goldberg, T | 2 |
| Oberstein, R | 1 |
| Dardaine, V | 1 |
| Peppa, M | 2 |
| Rayfield, EJ | 1 |
| Hunsaker, LA | 4 |
| Uribarri, J | 1 |
| Lu, M | 1 |
| Baliga, S | 1 |
| Vassalotti, JA | 1 |
| Beisswenger, P | 1 |
| Ruggiero-Lopez, D | 1 |
| Howell, SK | 1 |
| Nelson, RG | 1 |
| Mauer, M | 1 |
| Szwergold, BS | 1 |
| Woltjer, RL | 1 |
| Maezawa, I | 1 |
| Ou, JJ | 1 |
| Montine, KS | 1 |
| Montine, TJ | 1 |
| Du, J | 1 |
| Zeng, J | 1 |
| Ou, X | 1 |
| Ren, X | 1 |
| Cai, S | 1 |
| Kang, JH | 1 |
| Padival, S | 1 |
| Nagaraj, RH | 1 |
| Ahmad, MS | 1 |
| Pischetsrieder, M | 1 |
| Ahmed, N | 1 |
| Cantero, AV | 1 |
| Portero-Otín, M | 1 |
| Ayala, V | 1 |
| Auge, N | 1 |
| Sanson, M | 1 |
| Elbaz, M | 1 |
| Thiers, JC | 1 |
| Pamplona, R | 1 |
| Salvayre, R | 1 |
| Nègre-Salvayre, A | 1 |
| Price, CL | 1 |
| Knight, SC | 1 |
| Aleksandrovski, YA | 1 |
| Kalapos, MP | 1 |
| Jahan, I | 1 |
| Ng, R | 1 |
| Hassebrook, RK | 1 |
| Brown, WM | 1 |
| Royer, RE | 1 |
| Robinson, B | 1 |
| Taylor, KK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers[NCT03137966] | Phase 2 | 174 participants (Anticipated) | Interventional | 2022-12-30 | Not yet recruiting | ||
| Efficacy and Safety of Metformin Glycinate Compared to Metformin Hydrochloride on the Progression of Type 2 Diabetes[NCT04943692] | Phase 3 | 500 participants (Anticipated) | Interventional | 2021-08-31 | Suspended (stopped due to Administrative decision of the investigation direction) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
19 reviews available for pyruvaldehyde and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
Diabetes and Cognitive Impairment: A Role for Glucotoxicity and Dopaminergic Dysfunction.
Topics: Animals; Cognition; Cognitive Dysfunction; Diabetes Complications; Diabetes Mellitus; Diabetes Melli | 2021 |
Methylglyoxal and Advanced Glycation End Products in Patients with Diabetes - What We Know so Far and the Missing Links.
Topics: Diabetes Complications; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glycation End Products | 2019 |
Effects of the Reactive Metabolite Methylglyoxal on Cellular Signalling, Insulin Action and Metabolism - What We Know in Mammals and What We Can Learn From Yeast.
Topics: Adipocytes; Animals; Diabetes Complications; Humans; Insulin-Secreting Cells; Mammals; Oxidative Str | 2019 |
Alpha-Synuclein Glycation and the Action of Anti-Diabetic Agents in Parkinson's Disease.
Topics: alpha-Synuclein; Diabetes Complications; Glucose; Glycation End Products, Advanced; Glycosylation; H | 2018 |
Role of Methylglyoxal in Diabetic Cardiovascular and Kidney Diseases: Insights from Basic Science for Application into Clinical Practice.
Topics: Animals; Cardiovascular Diseases; Diabetes Complications; Humans; Kidney Diseases; Pyruvaldehyde | 2018 |
Methylglyoxal, a potent inducer of AGEs, connects between diabetes and cancer.
Topics: Animals; Diabetes Complications; Glycation End Products, Advanced; Humans; Hyperglycemia; Meta-Analy | 2019 |
Reactive metabolites as a cause of late diabetic complications.
Topics: Animals; Diabetes Complications; Diabetic Neuropathies; Glycation End Products, Advanced; Humans; La | 2014 |
Methylglyoxal in diabetes: link to treatment, glycaemic control and biomarkers of complications.
Topics: Animals; Diabetes Complications; Glycation End Products, Advanced; Humans; Mass Spectrometry; Metfor | 2014 |
Cells producing their own nemesis: understanding methylglyoxal metabolism.
Topics: Animals; Bacterial Infections; Diabetes Complications; Energy Metabolism; Glucose; Humans; Pyruvalde | 2014 |
The role of methylglyoxal and the glyoxalase system in diabetes and other age-related diseases.
Topics: Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus, Type 2; Diabetic Angiopathies; D | 2015 |
Methylglyoxal, diabetes mellitus and diabetic complications.
Topics: Aldehydes; Diabetes Complications; Diabetes Mellitus; Glycation End Products, Advanced; Humans; Insu | 2008 |
A brief critical overview of the biological effects of methylglyoxal and further evaluation of a methylglyoxal-based anticancer formulation in treating cancer patients.
Topics: Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Clinical Trials as Topic; Diabetes Complica | 2008 |
Glycotoxines, carbonyl stress and relevance to diabetes and its complications.
Topics: Diabetes Complications; Glycation End Products, Advanced; Humans; Oxidative Stress; Pyruvaldehyde | 2010 |
Metformin inhibition of glycation processes.
Topics: Azepines; Deoxyglucose; Diabetes Complications; Diabetes Mellitus; Glycation End Products, Advanced; | 2003 |
Alpha-oxoaldehyde metabolism and diabetic complications.
Topics: Aldehydes; Diabetes Complications; Diabetes Mellitus; Glyceraldehyde-3-Phosphate Dehydrogenases; Hum | 2003 |
Advanced glycation: a novel outlook on atherosclerosis.
Topics: Animals; Atherosclerosis; Bacterial Infections; Cysteine Endopeptidases; Dendritic Cells; Diabetes C | 2007 |
Glutathione-dependent detoxification of alpha-oxoaldehydes by the glyoxalase system: involvement in disease mechanisms and antiproliferative activity of glyoxalase I inhibitors.
Topics: Aldehydes; Animals; Apoptosis; Cell Division; Cytokines; Diabetes Complications; Diabetes Mellitus; | 1998 |
Molecular mechanisms of diabetic complications.
Topics: Diabetes Complications; Diabetes Mellitus; Enzyme Activation; Humans; Neutrophils; Protein Kinase C; | 1998 |
Methylglyoxal in living organisms: chemistry, biochemistry, toxicology and biological implications.
Topics: Animals; Bacteria; Diabetes Complications; Diabetes Mellitus; Drug Contamination; Energy Metabolism; | 1999 |
2 trials available for pyruvaldehyde and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
Skin beautification with oral non-hydrolized versions of carnosine and carcinine: Effective therapeutic management and cosmetic skincare solutions against oxidative glycation and free-radical production as a causal mechanism of diabetic complications and
Topics: Adolescent; Adult; Aged; Carnosine; Ceruloplasmin; Dermatologic Agents; Diabetes Complications; Doub | 2012 |
Inflammatory mediators are induced by dietary glycotoxins, a major risk factor for diabetic angiopathy.
Topics: Biomarkers; C-Reactive Protein; Cross-Over Studies; Diabetes Complications; Diabetes Mellitus; Diabe | 2002 |
36 other studies available for pyruvaldehyde and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
The activity of glyoxylase 1 is regulated by glucose-responsive phosphorylation on Tyr136.
Topics: Animals; Diabetes Complications; Diabetes Mellitus; Glucose; Glycation End Products, Advanced; HEK29 | 2022 |
Methylglyoxal and glyoxalase 1-a metabolic stress pathway-linking hyperglycemia to the unfolded protein response and vascular complications of diabetes.
Topics: Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Humans; Hyperglycemia; Insulin R | 2022 |
Barley Phenolamides Effectively Scavenge Harmful Methylglyoxal In Vitro and in Mice.
Topics: Animals; Diabetes Complications; Diabetes Mellitus; Glycation End Products, Advanced; Hordeum; Mice; | 2023 |
Bombax ceiba (Linn.) calyxes ameliorate methylglyoxal-induced oxidative stress via modulation of RAGE expression: identification of active phytometabolites by GC-MS analysis.
Topics: Antioxidants; Bombax; Cell Survival; Diabetes Complications; Gas Chromatography-Mass Spectrometry; G | 2020 |
N‑acetylcysteine inhibits atherosclerosis by correcting glutathione‑dependent methylglyoxal elimination and dicarbonyl/oxidative stress in the aorta of diabetic mice.
Topics: Acetylcysteine; Animals; Aorta; Atherosclerosis; Diabetes Complications; Diabetes Mellitus, Experime | 2021 |
Targeting Methylglyoxal in Diabetic Kidney Disease Using the Mitochondria-Targeted Compound MitoGamide.
Topics: Animals; Benzamides; Diabetes Complications; Diabetes Mellitus, Experimental; Disease Models, Animal | 2021 |
Gold Nanoparticle-Bioconjugated Aminoguanidine Inhibits Glycation Reaction: An
Topics: Animals; Blood Glucose; Diabetes Complications; Diabetes Mellitus, Experimental; Disease Models, Ani | 2021 |
The structural damages of lens crystallins induced by peroxynitrite and methylglyoxal, two causative players in diabetic complications and preventive role of lens antioxidant components.
Topics: Animals; Antioxidants; Ascorbic Acid; Cattle; Crystallins; Cytoprotection; Diabetes Complications; G | 2017 |
Contribution of methylglyoxal to delayed healing of bone injury in diabetes.
Topics: Animals; Blood Glucose; Bone and Bones; Cell Line; Diabetes Complications; Diabetes Mellitus, Experi | 2017 |
Reactions between methylglyoxal and its scavengers in-vivo appear to be catalyzed enzymatically.
Topics: Aldehydes; Carbon; Cardiovascular Agents; Catalysis; Diabetes Complications; Dihydroxyacetone; Fruct | 2017 |
Effects of glycation on human γd-crystallin proteins by different glycation-inducing agents.
Topics: Cataract; Diabetes Complications; Fructosamine; Galactose; gamma-Crystallins; Glycation End Products | 2018 |
Ratiometric Fluorescent Probe for Monitoring Endogenous Methylglyoxal in Living Cells and Diabetic Blood Samples.
Topics: Case-Control Studies; Cell Survival; Diabetes Complications; Diabetes Mellitus; Fluorescent Dyes; Hu | 2019 |
Edaravone protected human brain microvascular endothelial cells from methylglyoxal-induced injury by inhibiting AGEs/RAGE/oxidative stress.
Topics: Antipyrine; Blotting, Western; Brain; Diabetes Complications; Edaravone; Endothelial Cells; Glycatio | 2013 |
Glycation of vitronectin inhibits VEGF-induced angiogenesis by uncoupling VEGF receptor-2-αvβ3 integrin cross-talk.
Topics: Animals; Cell Line; Cell Movement; Cell Proliferation; Diabetes Complications; Diabetes Mellitus, Ex | 2015 |
Glyoxalase 1-knockdown in human aortic endothelial cells - effect on the proteome and endothelial function estimates.
Topics: Aorta; Apoptosis; Cells, Cultured; Chemokine CCL2; Collagen; Diabetes Complications; Endothelin-1; E | 2016 |
[Methylglyoxal-induced apoptosis of endothelial cells].
Topics: Animals; Apoptosis; Caspase 3; Cattle; Cells, Cultured; Diabetes Complications; Diabetes Mellitus; D | 2008 |
Dietary soy isoflavones increase insulin secretion and prevent the development of diabetic cataracts in streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Cataract; Diabetes Complications; Diabetes Mellitus, Experimental; Diet; Glu | 2008 |
Heat shock protein 27 modification is increased in the human diabetic failing heart.
Topics: Adult; Aged; Animals; Cardiomyopathies; Cell Line; Diabetes Complications; Female; Heart; HSP27 Heat | 2009 |
The molecular basis for impaired hypoxia-induced VEGF expression in diabetic tissues.
Topics: Animals; Cells, Cultured; Deferoxamine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus | 2009 |
Stilbene glucoside from Polygonum multiflorum Thunb.: a novel natural inhibitor of advanced glycation end product formation by trapping of methylglyoxal.
Topics: Chromatography, Liquid; Diabetes Complications; Diabetes Mellitus; Glucosides; Glycation End Product | 2010 |
Myoglobin-H2O2 catalyzes the oxidation of β-ketoacids to α-dicarbonyls: mechanism and implications in ketosis.
Topics: Acetoacetates; Biocatalysis; Diabetes Complications; Diacetyl; Humans; Ketosis; Myoglobin; Oxidation | 2011 |
High levels of IgM against methylglyoxal-modified apolipoprotein B100 are associated with less coronary artery calcification in patients with type 2 diabetes.
Topics: Apolipoprotein B-100; Autoantibodies; Coronary Artery Disease; Diabetes Complications; Diabetes Mell | 2012 |
Fisetin lowers methylglyoxal dependent protein glycation and limits the complications of diabetes.
Topics: Animals; Anxiety; Cell Line; Diabetes Complications; Diabetes Mellitus; Flavonoids; Flavonols; Glyco | 2011 |
Epidermal growth factor receptor transactivation is necessary for glucagon-like peptide-1 to protect PC12 cells from apoptosis.
Topics: Animals; Apoptosis; Brain Diseases, Metabolic; Cytoprotection; Diabetes Complications; ErbB Receptor | 2013 |
Methylglyoxal metabolism and diabetic complications: roles of aldose reductase, glyoxalase-I, betaine aldehyde dehydrogenase and 2-oxoaldehyde dehydrogenase.
Topics: Aldehyde Oxidoreductases; Aldehyde Reductase; Betaine-Aldehyde Dehydrogenase; Diabetes Complications | 2003 |
Dietary glycotoxins correlate with circulating advanced glycation end product levels in renal failure patients.
Topics: Cross-Sectional Studies; Diabetes Complications; Diabetes Mellitus; Diet; Diet Records; Food Analysi | 2003 |
Advanced glycation endproduct precursor alters intracellular amyloid-beta/A beta PP carboxy-terminal fragment aggregation and cytotoxicity.
Topics: Adaptor Proteins, Signal Transducing; alpha-Tocopherol; Alzheimer Disease; Amyloid beta-Protein Prec | 2003 |
Methylglyoxal downregulates Raf-1 protein through a ubiquitination-mediated mechanism.
Topics: Cell Culture Techniques; Diabetes Complications; Down-Regulation; Humans; Oxidation-Reduction; Phosp | 2006 |
Oxidative modification of human ceruloplasmin by methylglyoxal: an in vitro study.
Topics: Cation Transport Proteins; Ceruloplasmin; Copper; Copper Transport Proteins; Diabetes Complications; | 2006 |
Pyridoxamine inhibits maillard reactions in diabetic rat lenses.
Topics: Aldehyde Reductase; Animals; Arginine; Chromatography, High Pressure Liquid; Diabetes Complications; | 2006 |
Aged garlic extract and S-allyl cysteine prevent formation of advanced glycation endproducts.
Topics: Aging; Antioxidants; Cysteine; Diabetes Complications; Electrophoresis, Polyacrylamide Gel; Free Rad | 2007 |
Methylglyoxal induces advanced glycation end product (AGEs) formation and dysfunction of PDGF receptor-beta: implications for diabetic atherosclerosis.
Topics: Animals; Aorta; Apolipoproteins E; Arginine; Atherosclerosis; Becaplermin; Cell Movement; Cell Proli | 2007 |
Substrate specificity of reduced and oxidized forms of human aldose reductase.
Topics: Aldehyde Reductase; Diabetes Complications; Diabetes Mellitus; Humans; In Vitro Techniques; Kinetics | 1993 |
Suppression of the accumulation of triosephosphates and increased formation of methylglyoxal in human red blood cells during hyperglycaemia by thiamine in vitro.
Topics: Deoxyglucose; Diabetes Complications; Diabetes Mellitus; Erythrocytes; Glucose; Glycolysis; Humans; | 2001 |
Metabolism of the 2-oxoaldehyde methylglyoxal by aldose reductase and by glyoxalase-I: roles for glutathione in both enzymes and implications for diabetic complications.
Topics: Aldehyde Reductase; Binding Sites; Diabetes Complications; Diabetes Mellitus; Glutathione; Humans; I | 2001 |
Reduction of trioses by NADPH-dependent aldo-keto reductases. Aldose reductase, methylglyoxal, and diabetic complications.
Topics: Acetone; Aldehyde Reductase; Diabetes Complications; Diabetes Mellitus; Female; Glucose; Humans; Kin | 1992 |