pyruvaldehyde has been researched along with Cataract in 15 studies
Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.
Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the formation of imidazolysine, a Maillard reaction derived protein crosslink in the human lens in relation to aging and cataract by immunochemical methods." | 3.70 | Immunochemical detection of dicarbonyl-derived imidazolium protein crosslinks in human lenses. ( Nagaraj, RH; Shamsi, FA, 1999) |
| "Age-related cataracts are a leading cause of blindness." | 1.40 | Methylglyoxal induces endoplasmic reticulum stress and DNA demethylation in the Keap1 promoter of human lens epithelial cells and age-related cataracts. ( Augusteyn, RC; Ayaki, M; Bidasee, KR; Chan, JY; Palsamy, P; Shinohara, T, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 6 (40.00) | 29.6817 |
| 2010's | 5 (33.33) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Ma, Y | 1 |
| Liu, F | 1 |
| Xu, Y | 1 |
| Nandi, SK | 1 |
| Rankenberg, J | 1 |
| Glomb, MA | 1 |
| Nagaraj, RH | 5 |
| Pettem, CM | 1 |
| Briens, JM | 1 |
| Janz, DM | 1 |
| Weber, LP | 1 |
| Li, CT | 1 |
| How, SC | 1 |
| Chen, ME | 1 |
| Lo, CH | 1 |
| Chun, MC | 1 |
| Chang, CK | 1 |
| Chen, WA | 1 |
| Wu, JW | 1 |
| Wang, SS | 1 |
| Palsamy, P | 1 |
| Bidasee, KR | 1 |
| Ayaki, M | 1 |
| Augusteyn, RC | 1 |
| Chan, JY | 1 |
| Shinohara, T | 1 |
| Karumanchi, DK | 1 |
| Karunaratne, N | 1 |
| Lurio, L | 1 |
| Dillon, JP | 1 |
| Gaillard, ER | 1 |
| Lu, MP | 1 |
| Wang, R | 1 |
| Song, X | 1 |
| Chibbar, R | 1 |
| Wang, X | 1 |
| Wu, L | 1 |
| Meng, QH | 1 |
| Talukdar, D | 1 |
| Chaudhuri, BS | 1 |
| Ray, M | 1 |
| Ray, S | 1 |
| Ahmed, N | 1 |
| Thornalley, PJ | 2 |
| Dawczynski, J | 1 |
| Franke, S | 1 |
| Strobel, J | 1 |
| Stein, G | 1 |
| Haik, GM | 2 |
| Oya-Ito, T | 2 |
| Liu, BF | 1 |
| Linetsky, MD | 1 |
| Shipova, EV | 1 |
| Biswas, A | 1 |
| Miller, A | 1 |
| Bhat, M | 1 |
| Lo, TW | 1 |
| Shamsi, FA | 2 |
| Lin, K | 1 |
| Sady, C | 1 |
15 other studies available for pyruvaldehyde and Cataract
| Article | Year |
|---|---|
Protective Effect of β-Glucogallin on Damaged Cataract Against Methylglyoxal Induced Oxidative Stress in Cultured Lens Epithelial Cells.
Topics: 3T3 Cells; Animals; Antioxidants; Cataract; Cell Line; Chemokine CCL2; Chemokines; China; Cytokines; | 2019 |
Transient elevation of temperature promotes cross-linking of α-crystallin-client proteins through formation of advanced glycation endproducts: A potential role in presbyopia and cataracts.
Topics: alpha-Crystallin B Chain; Arginine; Cataract; Citrate (si)-Synthase; Cross-Linking Reagents; Glycati | 2020 |
Cardiometabolic response of juvenile rainbow trout exposed to dietary selenomethionine.
Topics: Animals; Antioxidants; Behavior, Animal; Body Weight; Cataract; Diet; Energy Metabolism; Female; Glu | 2018 |
Effects of glycation on human γd-crystallin proteins by different glycation-inducing agents.
Topics: Cataract; Diabetes Complications; Fructosamine; Galactose; gamma-Crystallins; Glycation End Products | 2018 |
Methylglyoxal induces endoplasmic reticulum stress and DNA demethylation in the Keap1 promoter of human lens epithelial cells and age-related cataracts.
Topics: Aging; Animals; Blotting, Western; Cataract; Cells, Cultured; Diabetes Mellitus, Experimental; DNA M | 2014 |
Non-enzymatic glycation of α-crystallin as an in vitro model for aging, diabetes and degenerative diseases.
Topics: Aging; alpha-Crystallins; Animals; Apoptosis; Cataract; Cattle; Diabetes Mellitus; Disease Models, A | 2015 |
Dietary soy isoflavones increase insulin secretion and prevent the development of diabetic cataracts in streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Cataract; Diabetes Complications; Diabetes Mellitus, Experimental; Diet; Glu | 2008 |
Critical evaluation of toxic versus beneficial effects of methylglyoxal.
Topics: Animals; Arginine; Cataract; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Delive | 2009 |
Methylglyoxal-derived hydroimidazolone advanced glycation end-products of human lens proteins.
Topics: Aged; Arginine; Cataract; Chromatography, High Pressure Liquid; Crystallins; Female; Fluorometry; Gl | 2003 |
Effect of methylglyoxal modification and phosphorylation on the chaperone and anti-apoptotic properties of heat shock protein 27.
Topics: Age Factors; Aged; alpha-Crystallins; Animals; Apoptosis Regulatory Proteins; Caspase 3; Caspase 9; | 2006 |
Convenient synthesis of GOLD and MOLD and identification of their oxidation products in vitro and in vivo.
Topics: Acetic Acid; Animals; Cataract; Chemistry; Chromatography, Liquid; Crystallins; Hydrogen Peroxide; H | 2007 |
The other side of the Maillard reaction.
Topics: Aging; Cataract; Glycation End Products, Advanced; Humans; Lens, Crystalline; Maillard Reaction; Pyr | 2008 |
Methylglyoxal concentration and glyoxalase activities in the human lens.
Topics: Age Factors; Aged; Cataract; Diabetes Mellitus; Female; Humans; Lactoylglutathione Lyase; Lens, Crys | 1994 |
Methylglyoxal-derived modifications in lens aging and cataract formation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Animals; Blotting, Western; Cataract; Cattle; Chi | 1998 |
Immunochemical detection of dicarbonyl-derived imidazolium protein crosslinks in human lenses.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antibodies; Antibody Specificity; Binding, Comp | 1999 |