pyruvaldehyde has been researched along with Cardiometabolic Syndrome in 12 studies
Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.
Cardiometabolic Syndrome: A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components not only include metabolic dysfunctions of METABOLIC SYNDROME but also HYPERTENSION, and ABDOMINAL OBESITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Body weight gain, fat deposits, dyslipidemia, hyperglycemia, and fatty liver were ameliorated by dietary genistein in both studies." | 3.91 | Dietary Genistein Inhibits Methylglyoxal-Induced Advanced Glycation End Product Formation in Mice Fed a High-Fat Diet. ( Sang, S; Wang, P; Zhao, Y, 2019) |
| " Significant beneficial health effects were observed at 16-week with the doubling of ergothioneine from baseline, increases in the antioxidant marker ORAC (oxygen radical absorption capacity) and anti-inflammatory hormone, adiponectin and significant decreases in serum oxidative stress inducing factors, carboxymethyllysine (CML) and methylglyoxal (MG), but no change in the lipid oxidative stress marker 8-isoprostane, leptin or measures of insulin resistance or glucose metabolism." | 3.83 | A Retrospective Study in Adults with Metabolic Syndrome: Diabetic Risk Factor Response to Daily Consumption of Agaricus bisporus (White Button Mushrooms). ( Beelman, RB; Cai, W; Calvo, MS; Goh, BC; Kalaras, MD; Mehrotra, A; Nadkarni, G; Uribarri, J; Wang, L, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 10 (83.33) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Ahmed, OAA | 1 |
| El-Bassossy, HM | 1 |
| Azhar, AS | 1 |
| Tarkhan, MM | 1 |
| El-Mas, MM | 1 |
| Francisco, FA | 1 |
| Saavedra, LPJ | 1 |
| Junior, MDF | 1 |
| Barra, C | 1 |
| Matafome, P | 1 |
| Mathias, PCF | 1 |
| Gomes, RM | 1 |
| Erkin-Cakmak, A | 1 |
| Bains, Y | 1 |
| Caccavello, R | 1 |
| Noworolski, SM | 1 |
| Schwarz, JM | 1 |
| Mulligan, K | 1 |
| Lustig, RH | 1 |
| Gugliucci, A | 2 |
| Zhao, Y | 1 |
| Wang, P | 1 |
| Sang, S | 1 |
| Cai, W | 2 |
| Uribarri, J | 2 |
| Zhu, L | 1 |
| Chen, X | 1 |
| Swamy, S | 1 |
| Zhao, Z | 1 |
| Grosjean, F | 1 |
| Simonaro, C | 1 |
| Kuchel, GA | 1 |
| Schnaider-Beeri, M | 1 |
| Woodward, M | 1 |
| Striker, GE | 1 |
| Vlassara, H | 1 |
| Lovestone, S | 1 |
| Smith, U | 1 |
| Garrido, D | 1 |
| Rubin, T | 1 |
| Poidevin, M | 1 |
| Maroni, B | 1 |
| Le Rouzic, A | 1 |
| Parvy, JP | 1 |
| Montagne, J | 1 |
| Calvo, MS | 1 |
| Mehrotra, A | 1 |
| Beelman, RB | 1 |
| Nadkarni, G | 1 |
| Wang, L | 1 |
| Goh, BC | 1 |
| Kalaras, MD | 1 |
| Wang, J | 1 |
| Chang, T | 2 |
| Liu, J | 1 |
| Wang, R | 1 |
| Desai, K | 1 |
| Wu, L | 2 |
| Jia, X | 1 |
| Wilson, TW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Dietary Reduction of Advanced Glycation End Products to Prevent Cognitive Decline in Elderly Diabetics - a Randomized Pilot Trial[NCT02739971] | 75 participants (Actual) | Interventional | 2016-06-30 | Completed | |||
| Effects of Glycoxidative Stress on Human Aging[NCT00579774] | 438 participants (Actual) | Interventional | 2007-01-31 | Completed | |||
| The Effects of Daily Anti-inflammatory Supplementation on Foundation Pain Index Scores in Chronic Opiate Patients[NCT05896878] | 20 participants (Anticipated) | Interventional | 2023-07-10 | Enrolling by invitation | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pyruvaldehyde and Cardiometabolic Syndrome
| Article | Year |
|---|---|
Early AGEing and metabolic diseases: is perinatal exposure to glycotoxins programming for adult-life metabolic syndrome?
Topics: Aging; Animals; Female; Fetus; Glycation End Products, Advanced; Humans; Infant; Infant, Newborn; In | 2021 |
11 other studies available for pyruvaldehyde and Cardiometabolic Syndrome
| Article | Year |
|---|---|
Interference with AGEs formation and AGEs-induced vascular injury mediates curcumin vascular protection in metabolic syndrome.
Topics: Animals; Aorta; Curcumin; Disease Models, Animal; Endothelium, Vascular; Free Radical Scavengers; Gl | 2020 |
Isocaloric Fructose Restriction Reduces Serum d-Lactate Concentration in Children With Obesity and Metabolic Syndrome.
Topics: Adipose Tissue; Adolescent; Black or African American; Carbon-13 Magnetic Resonance Spectroscopy; Ch | 2019 |
Dietary Genistein Inhibits Methylglyoxal-Induced Advanced Glycation End Product Formation in Mice Fed a High-Fat Diet.
Topics: Adipose Tissue; Aldehyde Reductase; Animals; Diabetes Mellitus; Diet, High-Fat; Dietary Fats; Dyslip | 2019 |
Oral glycotoxins are a modifiable cause of dementia and the metabolic syndrome in mice and humans.
Topics: ADAM Proteins; ADAM10 Protein; Administration, Oral; Aged; Amyloid beta-Peptides; Amyloid Precursor | 2014 |
Oral glycotoxins are a modifiable cause of dementia and the metabolic syndrome in mice and humans.
Topics: ADAM Proteins; ADAM10 Protein; Administration, Oral; Aged; Amyloid beta-Peptides; Amyloid Precursor | 2014 |
Oral glycotoxins are a modifiable cause of dementia and the metabolic syndrome in mice and humans.
Topics: ADAM Proteins; ADAM10 Protein; Administration, Oral; Aged; Amyloid beta-Peptides; Amyloid Precursor | 2014 |
Oral glycotoxins are a modifiable cause of dementia and the metabolic syndrome in mice and humans.
Topics: ADAM Proteins; ADAM10 Protein; Administration, Oral; Aged; Amyloid beta-Peptides; Amyloid Precursor | 2014 |
Advanced glycation end products, dementia, and diabetes.
Topics: Animals; Dementia; Female; Glycation End Products, Advanced; Humans; Male; Metabolic Syndrome; Pyruv | 2014 |
Fatty acid synthase cooperates with glyoxalase 1 to protect against sugar toxicity.
Topics: Animals; Diabetes Mellitus, Type 2; Dietary Sucrose; Drosophila; Fatty Acid Synthase, Type I; Glycat | 2015 |
A Retrospective Study in Adults with Metabolic Syndrome: Diabetic Risk Factor Response to Daily Consumption of Agaricus bisporus (White Button Mushrooms).
Topics: Adiponectin; Adult; Agaricus; Antioxidants; beta-Glucans; Biomarkers; Body Mass Index; Chitin; Chole | 2016 |
Fructose surges damage hepatic adenosyl-monophosphate-dependent kinase and lead to increased lipogenesis and hepatic insulin resistance.
Topics: Adenosine Monophosphate; Adenylate Kinase; Allosteric Site; AMP-Activated Protein Kinases; Animals; | 2016 |
Methylglyoxal content in drinking coffee as a cytotoxic factor.
Topics: Animals; Apoptosis; Caffeine; Cell Proliferation; Chromatography, High Pressure Liquid; Coffee; Cyto | 2010 |
Upregulation of aldolase B and overproduction of methylglyoxal in vascular tissues from rats with metabolic syndrome.
Topics: Aldehyde Reductase; Amine Oxidase (Copper-Containing); Animals; Aorta; Cells, Cultured; Cytochrome P | 2011 |
Methylglyoxal mediates adipocyte proliferation by increasing phosphorylation of Akt1.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Cell Cycle Proteins; Cell Proliferation; Glutathione; Lactoylglut | 2012 |