pyruvaldehyde has been researched along with Carcinogenesis in 2 studies
Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.
Carcinogenesis: The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, we found that consumption of MG significantly deteriorated azoxymethane (AOM)-induced colonic preneoplastic lesions in ICR mice, in which biomarkers of oxidative stress and inflammation within the body and feces induced by MG-fueled carbonyl stress may have played important roles." | 7.88 | Methylglyoxal displays colorectal cancer-promoting properties in the murine models of azoxymethane and CT26 isografts. ( Lin, JA; Wu, CH; Yen, GC, 2018) |
| " In the present study, we found that consumption of MG significantly deteriorated azoxymethane (AOM)-induced colonic preneoplastic lesions in ICR mice, in which biomarkers of oxidative stress and inflammation within the body and feces induced by MG-fueled carbonyl stress may have played important roles." | 3.88 | Methylglyoxal displays colorectal cancer-promoting properties in the murine models of azoxymethane and CT26 isografts. ( Lin, JA; Wu, CH; Yen, GC, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, JA | 1 |
| Wu, CH | 1 |
| Yen, GC | 1 |
| Guo, Y | 1 |
| Zhang, Y | 1 |
| Yang, X | 1 |
| Lu, P | 1 |
| Yan, X | 1 |
| Xiao, F | 1 |
| Zhou, H | 1 |
| Wen, C | 1 |
| Shi, M | 1 |
| Lu, J | 1 |
| Meng, QH | 1 |
2 other studies available for pyruvaldehyde and Carcinogenesis
| Article | Year |
|---|---|
Methylglyoxal displays colorectal cancer-promoting properties in the murine models of azoxymethane and CT26 isografts.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Cell Line; Cholesterol, LDL; Colorectal Neoplasm | 2018 |
Effects of methylglyoxal and glyoxalase I inhibition on breast cancer cells proliferation, invasion, and apoptosis through modulation of MAPKs, MMP9, and Bcl-2.
Topics: Apoptosis; Breast Neoplasms; Carcinogenesis; Cell Proliferation; Female; Gene Expression Regulation, | 2016 |