pyruvaldehyde has been researched along with Breast Neoplasms in 12 studies
Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In an initial study we have reported that MG can synergistically act with 5-Fluorouracil (5-FU) to decreases the number of MCF-7 breast cancer cells (Ghosh S, Pal A, Ray M, 2017)." | 7.91 | Methylglyoxal in combination with 5-Fluorouracil elicits improved chemosensitivity in breast cancer through apoptosis and cell cycle inhibition. ( Ghosh, S; Pal, A; Ray, M, 2019) |
| "Tamoxifen is the standard adjuvant endocrine therapy for estrogen-receptor positive premenopausal breast cancer patients." | 7.80 | Differential response to α-oxoaldehydes in tamoxifen resistant MCF-7 breast cancer cells. ( Brömme, HJ; Hartig, R; Hirche, F; Kalinski, T; Korkmaz, S; Lykkesfeldt, AE; Nass, N; Roessner, A; Sel, S; Simm, A; Ward, A; Wiemann, S, 2014) |
| " In an initial study we have reported that MG can synergistically act with 5-Fluorouracil (5-FU) to decreases the number of MCF-7 breast cancer cells (Ghosh S, Pal A, Ray M, 2017)." | 3.91 | Methylglyoxal in combination with 5-Fluorouracil elicits improved chemosensitivity in breast cancer through apoptosis and cell cycle inhibition. ( Ghosh, S; Pal, A; Ray, M, 2019) |
| "Tamoxifen is the standard adjuvant endocrine therapy for estrogen-receptor positive premenopausal breast cancer patients." | 3.80 | Differential response to α-oxoaldehydes in tamoxifen resistant MCF-7 breast cancer cells. ( Brömme, HJ; Hartig, R; Hirche, F; Kalinski, T; Korkmaz, S; Lykkesfeldt, AE; Nass, N; Roessner, A; Sel, S; Simm, A; Ward, A; Wiemann, S, 2014) |
| "Triple-negative breast cancer is highly dependent on glycolysis and is typically treated with a combination of surgery, radiation therapy, and chemotherapy." | 1.72 | Naturally occurring deamidated triosephosphate isomerase is a promising target for cell-selective therapy in cancer. ( De la Mora-De la Mora, I; de Vos, P; Enríquez-Flores, S; Fernández-Lainez, C; Flores-López, LA; García-Torres, I; Gracia-Mora, I; Gutiérrez-Castrellón, P; López-Velázquez, G; Martínez-Pérez, Y; Olaya-Vargas, A, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 9 (75.00) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Enríquez-Flores, S | 1 |
| Flores-López, LA | 1 |
| De la Mora-De la Mora, I | 1 |
| García-Torres, I | 1 |
| Gracia-Mora, I | 1 |
| Gutiérrez-Castrellón, P | 1 |
| Fernández-Lainez, C | 1 |
| Martínez-Pérez, Y | 1 |
| Olaya-Vargas, A | 1 |
| de Vos, P | 1 |
| López-Velázquez, G | 1 |
| Ding, C | 1 |
| Wang, F | 1 |
| Dang, Y | 1 |
| Xu, Z | 1 |
| Li, L | 1 |
| Lai, Y | 1 |
| Yu, H | 1 |
| Luo, Y | 1 |
| Huang, R | 1 |
| Zhang, A | 1 |
| Zhang, W | 1 |
| Zheng, Q | 2 |
| Osunsade, A | 2 |
| David, Y | 2 |
| Roy, A | 1 |
| Sarker, S | 1 |
| Upadhyay, P | 1 |
| Pal, A | 2 |
| Adhikary, A | 1 |
| Jana, K | 1 |
| Ray, M | 2 |
| Nokin, MJ | 2 |
| Bellier, J | 1 |
| Durieux, F | 2 |
| Peulen, O | 2 |
| Rademaker, G | 1 |
| Gabriel, M | 1 |
| Monseur, C | 1 |
| Charloteaux, B | 1 |
| Verbeke, L | 1 |
| van Laere, S | 1 |
| Roncarati, P | 1 |
| Herfs, M | 1 |
| Lambert, C | 1 |
| Scheijen, J | 1 |
| Schalkwijk, C | 1 |
| Colige, A | 1 |
| Caers, J | 1 |
| Delvenne, P | 2 |
| Turtoi, A | 2 |
| Castronovo, V | 2 |
| Bellahcène, A | 2 |
| Omans, ND | 1 |
| Leicher, R | 1 |
| Agustinus, AS | 1 |
| Finkin-Groner, E | 1 |
| D'Ambrosio, H | 1 |
| Liu, B | 1 |
| Chandarlapaty, S | 1 |
| Liu, S | 1 |
| Ghosh, S | 1 |
| Nass, N | 1 |
| Brömme, HJ | 1 |
| Hartig, R | 1 |
| Korkmaz, S | 1 |
| Sel, S | 1 |
| Hirche, F | 1 |
| Ward, A | 1 |
| Simm, A | 1 |
| Wiemann, S | 1 |
| Lykkesfeldt, AE | 1 |
| Roessner, A | 1 |
| Kalinski, T | 1 |
| Guo, Y | 1 |
| Zhang, Y | 1 |
| Yang, X | 1 |
| Lu, P | 1 |
| Yan, X | 1 |
| Xiao, F | 1 |
| Zhou, H | 1 |
| Wen, C | 1 |
| Shi, M | 1 |
| Lu, J | 1 |
| Meng, QH | 1 |
| Peixoto, P | 1 |
| Chiavarina, B | 1 |
| Blomme, A | 1 |
| Costanza, B | 1 |
| Smargiasso, N | 1 |
| Baiwir, D | 1 |
| Scheijen, JL | 1 |
| Schalkwijk, CG | 1 |
| Leenders, J | 1 |
| De Tullio, P | 1 |
| Bianchi, E | 1 |
| Thiry, M | 1 |
| Uchida, K | 1 |
| Spiegel, DA | 1 |
| Cochrane, JR | 1 |
| Hutton, CA | 1 |
| De Pauw, E | 1 |
| Belpomme, D | 1 |
| Hutschenreuther, A | 1 |
| Bigl, M | 1 |
| Hemdan, NY | 1 |
| Debebe, T | 1 |
| Gaunitz, F | 1 |
| Birkenmeier, G | 1 |
| Synold, T | 1 |
| Xi, B | 1 |
| Wuenschell, GE | 1 |
| Tamae, D | 1 |
| Figarola, JL | 1 |
| Rahbar, S | 1 |
| Termini, J | 1 |
12 other studies available for pyruvaldehyde and Breast Neoplasms
| Article | Year |
|---|---|
Naturally occurring deamidated triosephosphate isomerase is a promising target for cell-selective therapy in cancer.
Topics: Breast Neoplasms; Female; Glycolysis; Humans; Proteins; Pyruvaldehyde; Sulfhydryl Compounds; Triose- | 2022 |
Imaging Tumorous Methylglyoxal by an Activatable Near-Infrared Fluorescent Probe for Monitoring Glyoxalase 1 Activity.
Topics: Animals; Apoptosis; Breast Neoplasms; Cell Proliferation; Enzyme Inhibitors; Female; Fluorescent Dye | 2019 |
Protein arginine deiminase 4 antagonizes methylglyoxal-induced histone glycation.
Topics: Animals; Arginine; Breast Neoplasms; Citrullination; Citrulline; Female; Glycosylation; Histones; Hu | 2020 |
Methylglyoxal at metronomic doses sensitizes breast cancer cells to doxorubicin and cisplatin causing synergistic induction of programmed cell death and inhibition of stemness.
Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Breast Neoplasms; Cell Line, Tumor; Cell Survi | 2018 |
Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Down-Regulation; Dual-Specificity Phosph | 2019 |
Reversible histone glycation is associated with disease-related changes in chromatin architecture.
Topics: Acetylation; Animals; Breast Neoplasms; Cell Line, Tumor; Epigenesis, Genetic; Female; Glycation End | 2019 |
Methylglyoxal in combination with 5-Fluorouracil elicits improved chemosensitivity in breast cancer through apoptosis and cell cycle inhibition.
Topics: A549 Cells; Animals; Antimetabolites, Antineoplastic; Apoptosis; Breast Neoplasms; Cell Cycle; Cell | 2019 |
Differential response to α-oxoaldehydes in tamoxifen resistant MCF-7 breast cancer cells.
Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Fema | 2014 |
Effects of methylglyoxal and glyoxalase I inhibition on breast cancer cells proliferation, invasion, and apoptosis through modulation of MAPKs, MMP9, and Bcl-2.
Topics: Apoptosis; Breast Neoplasms; Carcinogenesis; Cell Proliferation; Female; Gene Expression Regulation, | 2016 |
Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis.
Topics: Adaptor Proteins, Signal Transducing; Aerobiosis; Breast Neoplasms; Cell Line, Tumor; Cell Prolifera | 2016 |
Modulation of GLO1 Expression Affects Malignant Properties of Cells.
Topics: Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transforma | 2016 |
Advanced glycation end products of DNA: quantification of N2-(1-Carboxyethyl)-2'-deoxyguanosine in biological samples by liquid chromatography electrospray ionization tandem mass spectrometry.
Topics: Animals; Breast Neoplasms; Chromatography, High Pressure Liquid; DNA Adducts; Female; Glycation End | 2008 |