Page last updated: 2024-10-19

pyruvaldehyde and Autosomal Dominant Juvenile Parkinson Disease

pyruvaldehyde has been researched along with Autosomal Dominant Juvenile Parkinson Disease in 4 studies

Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.

Research Excerpts

ExcerptRelevanceReference
"Recently, the Parkinsonism-associated protein DJ-1 has been reported to exhibit deglycase activity that erases early glycation intermediates and stable AGEs from proteins."1.91Parkinsonism-Associated Protein DJ-1 Is an Antagonist, Not an Eraser, for Protein Glycation. ( Gao, Q; Jacob-Dolan, JW; Scheck, RA, 2023)
"We discovered recently that Parkinsonism-associated DJ-1 and its bacterial homologs function as protein deglycases that repair glyoxal- and methylglyoxal-glycated proteins."1.46Parkinsonism-associated protein DJ-1 is a bona fide deglycase. ( Dairou, J; Richarme, G, 2017)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Gao, Q1
Jacob-Dolan, JW1
Scheck, RA1
Richarme, G2
Mihoub, M1
Dairou, J2
Bui, LC1
Leger, T1
Lamouri, A1
Deng, Y1
Zhang, Y1
Li, Y1
Xiao, S1
Song, D1
Qing, H1
Li, Q1
Rajput, AH1

Other Studies

4 other studies available for pyruvaldehyde and Autosomal Dominant Juvenile Parkinson Disease

ArticleYear
Parkinsonism-Associated Protein DJ-1 Is an Antagonist, Not an Eraser, for Protein Glycation.
    Biochemistry, 2023, 03-21, Volume: 62, Issue:6

    Topics: Glycation End Products, Advanced; Glyoxal; Humans; Magnesium Oxide; Maillard Reaction; Parkinsonian

2023
Parkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal- and glyoxal-glycated cysteine, arginine, and lysine residues.
    The Journal of biological chemistry, 2015, Jan-16, Volume: 290, Issue:3

    Topics: Acetylcysteine; Albumins; Apoptosis; Arginine; Aspartate Aminotransferases; Catalysis; Cell Survival

2015
Parkinsonism-associated protein DJ-1 is a bona fide deglycase.
    Biochemical and biophysical research communications, 2017, 01-29, Volume: 483, Issue:1

    Topics: Acetylcysteine; Artifacts; Culture Media; Cysteine; Escherichia coli; Glucose; Glycation End Product

2017
Occurrence and distribution of salsolinol-like compound, 1-acetyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (ADTIQ) in parkinsonian brains.
    Journal of neural transmission (Vienna, Austria : 1996), 2012, Volume: 119, Issue:4

    Topics: Aged; Aged, 80 and over; Analysis of Variance; Brain; Chromatography, High Pressure Liquid; Dopamine

2012