Page last updated: 2024-10-19

pyruvaldehyde and Ataxia Telangiectasia

pyruvaldehyde has been researched along with Ataxia Telangiectasia in 2 studies

Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.

Ataxia Telangiectasia: An autosomal recessive inherited disorder characterized by choreoathetosis beginning in childhood, progressive CEREBELLAR ATAXIA; TELANGIECTASIS of CONJUNCTIVA and SKIN; DYSARTHRIA; B- and T-cell immunodeficiency, and RADIOSENSITIVITY to IONIZING RADIATION. Affected individuals are prone to recurrent sinobronchopulmonary infections, lymphoreticular neoplasms, and other malignancies. Serum ALPHA-FETOPROTEINS are usually elevated. (Menkes, Textbook of Child Neurology, 5th ed, p688) The gene for this disorder (ATM) encodes a cell cycle checkpoint protein kinase and has been mapped to chromosome 11 (11q22-q23).

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Degan, P2
d'Ischia, M2
Pallardó, FV2
Zatterale, A2
Brusco, A1
Calzone, R2
Cavalieri, S1
Kavakli, K1
Lloret, A2
Manini, P2
Pisanti, MA1
Vuttariello, E1
Pagano, G2
Dunster, C1
Kelly, FJ1

Reviews

1 review available for pyruvaldehyde and Ataxia Telangiectasia

ArticleYear
Different patterns of in vivo pro-oxidant states in a set of cancer- or aging-related genetic diseases.
    Free radical biology & medicine, 2008, Feb-15, Volume: 44, Issue:4

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adolescent; Adult; Aged; Ataxia Telangiectasia; Bloom Syndrome; Child;

2008

Other Studies

1 other study available for pyruvaldehyde and Ataxia Telangiectasia

ArticleYear
Glutathione levels in blood from ataxia telangiectasia patients suggest in vivo adaptive mechanisms to oxidative stress.
    Clinical biochemistry, 2007, Volume: 40, Issue:9-10

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adaptation, Physiological; Adolescent; Adult; Ataxia Telangiectasia; Ch

2007