pyruvaldehyde has been researched along with Angiogenesis, Pathologic in 9 studies
Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Early diabetic retinopathy is characterized by a loss of pericytes from retinal capillaries, the appearance of acellular capillaries and microaneurysms, and a breakdown of the blood-retinal barrier." | 2.49 | Advanced glycation end products and diabetic retinopathy. ( Brownstein, S; Milne, R, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 3 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Aihara, S | 1 |
| Nakano, T | 2 |
| Torisu, K | 1 |
| Kitazono, T | 2 |
| Kumiko, T | 1 |
| Mizumasa, T | 1 |
| Kuroki, Y | 1 |
| Tsuruya, K | 1 |
| Nguyen, H | 1 |
| Koh, JY | 1 |
| Li, H | 1 |
| Islas-Robles, A | 1 |
| Meda Venkata, SP | 1 |
| Wang, JM | 1 |
| Monks, TJ | 1 |
| Vulesevic, B | 1 |
| McNeill, B | 1 |
| Geoffrion, M | 1 |
| Kuraitis, D | 1 |
| McBane, JE | 1 |
| Lochhead, M | 1 |
| Vanderhyden, BC | 1 |
| Korbutt, GS | 1 |
| Milne, RW | 1 |
| Suuronen, EJ | 1 |
| Wang, L | 1 |
| Zhang, X | 1 |
| Pang, N | 1 |
| Xiao, L | 1 |
| Li, Y | 1 |
| Chen, N | 1 |
| Ren, M | 1 |
| Deng, X | 1 |
| Wu, J | 1 |
| Fan, YP | 1 |
| Hsia, CC | 1 |
| Tseng, KW | 1 |
| Liao, CK | 1 |
| Fu, TW | 1 |
| Ko, TL | 1 |
| Chiu, MM | 1 |
| Shih, YH | 1 |
| Huang, PY | 1 |
| Chiang, YC | 1 |
| Yang, CC | 1 |
| Fu, YS | 1 |
| Thangarajah, H | 1 |
| Yao, D | 1 |
| Chang, EI | 1 |
| Shi, Y | 1 |
| Jazayeri, L | 1 |
| Vial, IN | 1 |
| Galiano, RD | 1 |
| Du, XL | 1 |
| Grogan, R | 1 |
| Galvez, MG | 1 |
| Januszyk, M | 1 |
| Brownlee, M | 1 |
| Gurtner, GC | 1 |
| Milne, R | 1 |
| Brownstein, S | 1 |
| Berlanga, J | 1 |
| Cibrian, D | 1 |
| Guillén, I | 1 |
| Freyre, F | 1 |
| Alba, JS | 1 |
| Lopez-Saura, P | 1 |
| Merino, N | 1 |
| Aldama, A | 1 |
| Quintela, AM | 1 |
| Triana, ME | 1 |
| Montequin, JF | 1 |
| Ajamieh, H | 1 |
| Urquiza, D | 1 |
| Ahmed, N | 1 |
| Thornalley, PJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers[NCT03137966] | Phase 2 | 174 participants (Anticipated) | Interventional | 2022-12-30 | Not yet recruiting | ||
| The Relationship of Advanced Glycation Endproducts in the Anterior Lens Capsule to Glycemic Status and Diabetic Retinopathy: A Cross Sectional Study of Patients With and Without Type 2 Diabetes Mellitus Undergoing Cataract Surgery[NCT02662010] | 157 participants (Actual) | Observational | 2016-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pyruvaldehyde and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Advanced glycation end products and diabetic retinopathy.
Topics: Animals; Blood-Retinal Barrier; Diabetic Retinopathy; Glycation End Products, Advanced; Molecular Ta | 2013 |
8 other studies available for pyruvaldehyde and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Glucose degradation products in peritoneal dialysis solution impair angiogenesis by dysregulating angiogenetic factors in endothelial and vascular smooth muscle cells.
Topics: Angiogenesis Inducing Agents; Animals; Dialysis Solutions; Endothelial Cells; Glucose; Human Umbilic | 2022 |
The glucose degradation product methylglyoxal induces immature angiogenesis in patients undergoing peritoneal dialysis.
Topics: Angiogenesis Inducing Agents; Becaplermin; Female; Glucose; Glycation End Products, Advanced; Human | 2020 |
A novel imidazolinone metformin-methylglyoxal metabolite promotes endothelial cell angiogenesis via the eNOS/HIF-1α pathway.
Topics: Animals; Hindlimb; Hyperglycemia; Hypoglycemic Agents; Hypoxia-Inducible Factor 1, alpha Subunit; Im | 2021 |
Glyoxalase-1 overexpression in bone marrow cells reverses defective neovascularization in STZ-induced diabetic mice.
Topics: Angiogenic Proteins; Animals; Apoptosis; Blood Glucose; Bone Marrow Cells; Bone Marrow Transplantati | 2014 |
Glycation of vitronectin inhibits VEGF-induced angiogenesis by uncoupling VEGF receptor-2-αvβ3 integrin cross-talk.
Topics: Animals; Cell Line; Cell Movement; Cell Proliferation; Diabetes Complications; Diabetes Mellitus, Ex | 2015 |
The Therapeutic Potential of Human Umbilical Mesenchymal Stem Cells From Wharton's Jelly in the Treatment of Rat Peritoneal Dialysis-Induced Fibrosis.
Topics: Actins; Animals; Biomarkers; Cell Death; Culture Media; Disease Models, Animal; Epithelial Cells; Fi | 2016 |
The molecular basis for impaired hypoxia-induced VEGF expression in diabetic tissues.
Topics: Animals; Cells, Cultured; Deferoxamine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus | 2009 |
Methylglyoxal administration induces diabetes-like microvascular changes and perturbs the healing process of cutaneous wounds.
Topics: Animals; Blood Glucose; Cholesterol; Diabetic Angiopathies; Disease Models, Animal; Fructosamine; In | 2005 |