pyruvaldehyde has been researched along with Allodynia in 4 studies
Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This hyperalgesia is reflected by increased blood flow in brain regions that are involved in pain processing." | 1.38 | Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy. ( Babes, A; Bierhaus, A; Brownlee, M; Cooper, ME; Dehmer, T; Eberhardt, M; Edelstein, D; Elvert, R; Fleming, T; Forbes, J; Haberkorn, U; Humpert, PM; Kichko, TI; Konrade, I; Lasischka, F; Lasitschka, F; Leffler, A; Lukic, IK; Mier, W; Morcos, M; Nau, C; Nawroth, PP; Neacsu, C; Neuhuber, WL; Pirags, V; Rabbani, N; Reeh, PW; Sauer, SK; Schnölzer, M; Schwaninger, M; Stern, DM; Stoyanov, S; Thornalley, PJ; Ziegler, D, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Santos, DFS | 1 |
| Donahue, RR | 1 |
| Laird, DE | 1 |
| Oliveira, MCG | 1 |
| Taylor, BK | 1 |
| Huang, Q | 1 |
| Chen, Y | 1 |
| Gong, N | 1 |
| Wang, YX | 1 |
| Viisanen, H | 1 |
| Chapman, H | 1 |
| Wei, H | 1 |
| Lasierra Losada, M | 1 |
| Koivisto, A | 1 |
| Akerman, KE | 1 |
| Pertovaara, A | 1 |
| Bierhaus, A | 1 |
| Fleming, T | 1 |
| Stoyanov, S | 1 |
| Leffler, A | 1 |
| Babes, A | 1 |
| Neacsu, C | 1 |
| Sauer, SK | 1 |
| Eberhardt, M | 1 |
| Schnölzer, M | 1 |
| Lasitschka, F | 1 |
| Lasischka, F | 1 |
| Neuhuber, WL | 1 |
| Kichko, TI | 1 |
| Konrade, I | 1 |
| Elvert, R | 1 |
| Mier, W | 1 |
| Pirags, V | 1 |
| Lukic, IK | 1 |
| Morcos, M | 1 |
| Dehmer, T | 1 |
| Rabbani, N | 1 |
| Thornalley, PJ | 1 |
| Edelstein, D | 1 |
| Nau, C | 1 |
| Forbes, J | 1 |
| Humpert, PM | 1 |
| Schwaninger, M | 1 |
| Ziegler, D | 1 |
| Stern, DM | 1 |
| Cooper, ME | 1 |
| Haberkorn, U | 1 |
| Brownlee, M | 1 |
| Reeh, PW | 1 |
| Nawroth, PP | 1 |
4 other studies available for pyruvaldehyde and Allodynia
| Article | Year |
|---|---|
The PPARγ agonist pioglitazone produces a female-predominant inhibition of hyperalgesia associated with surgical incision, peripheral nerve injury, and painful diabetic neuropathy.
Topics: Analgesics; Animals; Diabetic Neuropathies; Disease Models, Animal; Female; Hyperalgesia; Male; Mice | 2022 |
Methylglyoxal mediates streptozotocin-induced diabetic neuropathic pain via activation of the peripheral TRPA1 and Nav1.8 channels.
Topics: Analgesics; Aniline Compounds; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Neu | 2016 |
Pronociceptive effects induced by cutaneous application of a transient receptor potential ankyrin 1 (TRPA1) channel agonist methylglyoxal in diabetic animals: comparison with tunicamycin-induced endoplastic reticulum stress.
Topics: Administration, Cutaneous; Animals; Behavior, Animal; Diabetes Mellitus, Experimental; Endoplasmic R | 2016 |
Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy.
Topics: Animals; Cerebrovascular Circulation; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Humans | 2012 |