pyruvaldehyde has been researched along with Albuminuria in 7 studies
Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.
Albuminuria: The presence of albumin in the urine, an indicator of KIDNEY DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated, in individuals with type 2 diabetes, whether irbesartan lowered plasma levels of the dicarbonyls methylglyoxal, glyoxal, 3-deoxyglucosone and their derived advanced glycation end products (AGEs), and increased d-lactate, reflecting greater methylglyoxal flux." | 7.01 | Irbesartan treatment does not influence plasma levels of the dicarbonyls methylglyoxal, glyoxal and 3-deoxyglucosone in participants with type 2 diabetes and microalbuminuria: An IRMA2 sub-study. ( Hanssen, NMJ; Hovind, P; Parving, HH; Persson, F; Piazza, M; Rossing, P; Schalkwijk, CG; Scheijen, JL; Stehouwer, CDA; van de Waarenburg, MPH; van Greevenbroek, MMJ, 2021) |
| " Secondary goals examined albuminuria, age, race, sex, and metformin prescription." | 5.20 | Effects of sevelamer carbonate on advanced glycation end products and antioxidant/pro-oxidant status in patients with diabetic kidney disease. ( Poretsky, L; Striker, GE; Vlassara, H; Woodward, M; Yubero-Serrano, EM, 2015) |
| "We investigated, in individuals with type 2 diabetes, whether irbesartan lowered plasma levels of the dicarbonyls methylglyoxal, glyoxal, 3-deoxyglucosone and their derived advanced glycation end products (AGEs), and increased d-lactate, reflecting greater methylglyoxal flux." | 3.01 | Irbesartan treatment does not influence plasma levels of the dicarbonyls methylglyoxal, glyoxal and 3-deoxyglucosone in participants with type 2 diabetes and microalbuminuria: An IRMA2 sub-study. ( Hanssen, NMJ; Hovind, P; Parving, HH; Persson, F; Piazza, M; Rossing, P; Schalkwijk, CG; Scheijen, JL; Stehouwer, CDA; van de Waarenburg, MPH; van Greevenbroek, MMJ, 2021) |
| "Candesartan treatment for 4 weeks significantly reduced these parameters." | 1.39 | Carbonyl stress induces hypertension and cardio-renal vascular injury in Dahl salt-sensitive rats. ( Chen, X; Endo, S; Guo, Q; Hu, C; Ito, S; Jiang, Y; Miyata, T; Mori, T; Nakayama, K; Nakayama, M; Ogawa, S; Ohsaki, Y; Yoneki, Y; Zhu, W, 2013) |
| "To assess the role of dAGE on type 1 diabetes, NOD mice were exposed to a high-AGE diet (H-AGE) and to a nutritionally similar diet with approximate fivefold-lower levels of N(epsilon)-carboxymethyllysine (CML) and methylglyoxal-derivatives (MG) (L-AGE)." | 1.32 | Fetal or neonatal low-glycotoxin environment prevents autoimmune diabetes in NOD mice. ( Hattori, M; He, C; McEvoy, R; Peppa, M; Vlassara, H; Zheng, F, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Darenskaya, MA | 1 |
| Chugunova, EV | 1 |
| Kolesnikov, SI | 1 |
| Grebenkina, LA | 1 |
| Semenova, NV | 1 |
| Nikitina, OA | 1 |
| Kolesnikova, LI | 1 |
| Piazza, M | 1 |
| Hanssen, NMJ | 1 |
| Persson, F | 1 |
| Scheijen, JL | 1 |
| van de Waarenburg, MPH | 1 |
| van Greevenbroek, MMJ | 1 |
| Rossing, P | 2 |
| Hovind, P | 1 |
| Stehouwer, CDA | 1 |
| Parving, HH | 1 |
| Schalkwijk, CG | 1 |
| Yubero-Serrano, EM | 1 |
| Woodward, M | 1 |
| Poretsky, L | 1 |
| Vlassara, H | 2 |
| Striker, GE | 1 |
| Jensen, TM | 1 |
| Vistisen, D | 1 |
| Fleming, T | 1 |
| Nawroth, PP | 1 |
| Jørgensen, ME | 1 |
| Lauritzen, T | 1 |
| Sandbaek, A | 1 |
| Witte, DR | 1 |
| Chen, X | 1 |
| Mori, T | 1 |
| Guo, Q | 1 |
| Hu, C | 1 |
| Ohsaki, Y | 1 |
| Yoneki, Y | 1 |
| Zhu, W | 1 |
| Jiang, Y | 1 |
| Endo, S | 1 |
| Nakayama, K | 1 |
| Ogawa, S | 1 |
| Nakayama, M | 1 |
| Miyata, T | 1 |
| Ito, S | 1 |
| Peppa, M | 1 |
| He, C | 1 |
| Hattori, M | 1 |
| McEvoy, R | 1 |
| Zheng, F | 1 |
| Wang, H | 1 |
| Meng, QH | 1 |
| Gordon, JR | 1 |
| Khandwala, H | 1 |
| Wu, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Irbesartan in Patients With Type 2 Diabetes and Microalbuminuria (IRMA 2)[NCT00317915] | Phase 3 | 0 participants | Interventional | Completed | |||
| The Effect of Sevelamer Carbonate on Serum Trimethylamine-n-Oxide (TMAO) Level in Patients With Chronic Kidney Disease (CKD) Stage 3b-4: a Protocol of a Randomized, Parallel, Controlled Trial[NCT03596749] | Phase 3 | 80 participants (Anticipated) | Interventional | 2018-09-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for pyruvaldehyde and Albuminuria
| Article | Year |
|---|---|
Irbesartan treatment does not influence plasma levels of the dicarbonyls methylglyoxal, glyoxal and 3-deoxyglucosone in participants with type 2 diabetes and microalbuminuria: An IRMA2 sub-study.
Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Biomarkers; Chromatography, Liquid; Deoxygluco | 2021 |
Effects of sevelamer carbonate on advanced glycation end products and antioxidant/pro-oxidant status in patients with diabetic kidney disease.
Topics: Adiponectin; Age Factors; Aged; Albuminuria; Chelating Agents; Diabetes Mellitus, Type 2; Diabetic N | 2015 |
Methylglyoxal is associated with changes in kidney function among individuals with screen-detected Type 2 diabetes mellitus.
Topics: Adult; Aged; Albuminuria; Creatinine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic N | 2016 |
4 other studies available for pyruvaldehyde and Albuminuria
| Article | Year |
|---|---|
Content of Carbonyl Compounds and Parameters of Glutathione Metabolism in Men with Type 1 Diabetes Mellitus at Preclinical Stages of Diabetic Nephropathy.
Topics: Adolescent; Adult; Albuminuria; Asymptomatic Diseases; Case-Control Studies; Diabetes Mellitus, Type | 2021 |
Carbonyl stress induces hypertension and cardio-renal vascular injury in Dahl salt-sensitive rats.
Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; B | 2013 |
Fetal or neonatal low-glycotoxin environment prevents autoimmune diabetes in NOD mice.
Topics: Administration, Oral; Aging; Albuminuria; Animals; Animals, Newborn; Blood Glucose; Creatinine; Cros | 2003 |
Proinflammatory and proapoptotic effects of methylglyoxal on neutrophils from patients with type 2 diabetes mellitus.
Topics: Aged; Albuminuria; Anti-Inflammatory Agents; Apoptosis; Blood Glucose; Caspase 3; Creatine; Cytokine | 2007 |