pyrrolidonecarboxylic acid and Diabetes Mellitus, Type 2

pyrrolidonecarboxylic acid has been researched along with Diabetes Mellitus, Type 2 in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.69)18.2507
2000's6 (46.15)29.6817
2010's5 (38.46)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Arakawa, S; Bamba, T; Fukusaki, E; Furuno, M; Katakami, N; Matsuoka, TA; Omori, K; Shimomura, I; Takahara, M; Taya, N; Tsugawa, H1
Chou, J; Li, Y; Liu, L; Liu, R; Liu, X; Sun, C; Yu, J; Zhao, X1
Adelson, D; Ao, Y; Chen, A; Go, VL; Ko, M; Liu, YY; Marvizon, JC; Song, MK; Yang, H1
Halmos, T; Suba, I1
Igarashi, K; Yoshinari, O1
Adelson, DW; Ao, Y; Chen, A; Go, VL; Nyby, MD; Smutko, V; Tuck, ML; Wijesuriya, J; Yang, H1
Bailey, CJ; Flatt, PR; Gault, VA; Green, BD; Greer, B; Harriott, P; Irwin, N; O'Harte, FP1
Ao, Y; Go, VL; Song, MK; Toy, N; Yang, H1
Bruce, CR; Carey, AL; Febbraio, MA; Hawley, JA; Pedersen, BK; Petersen, EW; Pilegaard, H; Southgate, RJ1
Aas, AM; Birkeland, KI; Diep, LM; Seljeflot, I; Thorsby, PM; Torjesen, PA1
Froguel, P; Lacquemant, C; Leprêtre, F; Vasseur, F1
Daval, M; Ferré, P; Foufelle, F1
Badaloo, V; Bennett, FI; Forrester, TE; Jackson, AA1

Reviews

3 review(s) available for pyrrolidonecarboxylic acid and Diabetes Mellitus, Type 2

ArticleYear
[Role of the brain in the regulation of metabolism and energy expenditure: the central role of insulin, and insulin resistance of the brain].
    Orvosi hetilap, 2011, Jan-16, Volume: 152, Issue:3

    Topics: Animals; Appetite Depressants; Appetite Regulation; Blood Glucose; Brain; Ceramides; Cognition; Diabetes Mellitus, Type 2; Energy Metabolism; Fatty Liver; Glucagon-Like Peptide 1; Humans; Hypothalamus; Incretins; Insulin; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Metabolic Syndrome; Neuropeptides; Non-alcoholic Fatty Liver Disease; Oligopeptides; Orexins; Pyrrolidonecarboxylic Acid

2011
[Adipocytokins, obesity and development of type 2 diabetes].
    Medecine sciences : M/S, 2005, Volume: 21 Spec No

    Topics: Adiponectin; Adipose Tissue; Animals; Diabetes Mellitus, Type 2; Energy Metabolism; Humans; Incidence; Insect Hormones; Insulin Resistance; Leptin; Mice; Obesity; Oligopeptides; Pyrrolidonecarboxylic Acid; Resistin

2005
[AMPK, an active player in the control of metabolism].
    Journal de la Societe de biologie, 2006, Volume: 200, Issue:1

    Topics: Adenylate Kinase; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Energy Metabolism; Fatty Acids; Homeostasis; Humans; Insect Hormones; Insulin; Leptin; Models, Biological; Oligopeptides; Prevalence; Pyrrolidonecarboxylic Acid

2006

Trials

1 trial(s) available for pyrrolidonecarboxylic acid and Diabetes Mellitus, Type 2

ArticleYear
Blood glucose lowering by means of lifestyle intervention has different effects on adipokines as compared with insulin treatment in subjects with type 2 diabetes.
    Diabetologia, 2006, Volume: 49, Issue:5

    Topics: Aged; Blood Glucose; Blood Pressure; Body Mass Index; Cholesterol; Cholesterol, HDL; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insect Hormones; Insulin; Life Style; Male; Middle Aged; Oligopeptides; Pyrrolidonecarboxylic Acid; Triglycerides

2006

Other Studies

9 other study(ies) available for pyrrolidonecarboxylic acid and Diabetes Mellitus, Type 2

ArticleYear
Plasma metabolites associated with arterial stiffness in patients with type 2 diabetes.
    Cardiovascular diabetology, 2020, 06-11, Volume: 19, Issue:1

    Topics: Aged; Ankle Brachial Index; Biomarkers; Diabetes Mellitus, Type 2; Erythritol; Female; Gas Chromatography-Mass Spectrometry; Humans; Indican; Male; Mannitol; Metabolomics; Middle Aged; Peripheral Arterial Disease; Pyrrolidonecarboxylic Acid; Vascular Stiffness

2020
Fasting serum α‑hydroxybutyrate and pyroglutamic acid as important metabolites for detecting isolated post-challenge diabetes based on organic acid profiles.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2018, Nov-15, Volume: 1100-1101

    Topics: Biomarkers; Carboxylic Acids; Diabetes Mellitus, Type 2; Fasting; Female; Humans; Hydroxybutyrates; Limit of Detection; Linear Models; Male; Metabolome; Middle Aged; Pyrrolidonecarboxylic Acid; Reproducibility of Results

2018
Potent hyperglycemic and hyperinsulinemic effects of thyrotropin-releasing hormone microinjected into the rostroventrolateral medulla and abnormal responses in type 2 diabetic rats.
    Neuroscience, 2010, Aug-25, Volume: 169, Issue:2

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Hyperglycemia; Hyperinsulinism; Insulin; Male; Medulla Oblongata; Microinjections; Nerve Fibers; Neural Pathways; Protein Precursors; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Spinal Cord; Thyrotropin-Releasing Hormone; Vagus Nerve

2010
Anti-diabetic effect of pyroglutamic acid in type 2 diabetic Goto-Kakizaki rats and KK-Ay mice.
    The British journal of nutrition, 2011, Volume: 106, Issue:7

    Topics: Animals; Diabetes Mellitus, Type 2; Dietary Supplements; Female; Glucokinase; Glucose Intolerance; Glucose-6-Phosphatase; Hypoglycemic Agents; Male; Mice; Mice, Inbred Strains; Molecular Structure; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains

2011
Role of brainstem thyrotropin-releasing hormone-triggered sympathetic overactivation in cardiovascular mortality in type 2 diabetic Goto-Kakizaki rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2012, Volume: 35, Issue:2

    Topics: Adrenal Glands; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Blood Glucose; Blood Pressure; Brain Stem; Cardiovascular Diseases; Cisterna Magna; Diabetes Mellitus, Type 2; Heart Rate; Inflammation; Injections; Irbesartan; Male; Myocardium; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; RNA, Messenger; Sympathetic Nervous System; Tetrazoles; Thyrotropin-Releasing Hormone; Vascular Cell Adhesion Molecule-1

2012
Degradation, insulin secretion, and antihyperglycemic actions of two palmitate-derivitized N-terminal pyroglutamyl analogues of glucose-dependent insulinotropic polypeptide.
    Journal of medicinal chemistry, 2005, Feb-24, Volume: 48, Issue:4

    Topics: Animals; Blood Glucose; Cell Line; Cricetinae; Cricetulus; Cyclic AMP; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dose-Response Relationship, Drug; Gastric Inhibitory Polypeptide; Hypoglycemic Agents; Insulin; Insulin Secretion; Mice; Mice, Obese; Palmitates; Pyrrolidonecarboxylic Acid; Structure-Activity Relationship

2005
Altered glucose and insulin responses to brain medullary thyrotropin-releasing hormone (TRH)-induced autonomic activation in type 2 diabetic Goto-Kakizaki rats.
    Endocrinology, 2005, Volume: 146, Issue:12

    Topics: Adrenalectomy; Animals; Autonomic Nervous System; Blood Glucose; Diabetes Mellitus, Type 2; Fasting; Female; Injections, Intraventricular; Insulin; Male; Medulla Oblongata; Pancreas; Protein Isoforms; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; RNA, Messenger; Thyrotropin-Releasing Hormone; Vagotomy

2005
Discordant gene expression in skeletal muscle and adipose tissue of patients with type 2 diabetes: effect of interleukin-6 infusion.
    Diabetologia, 2006, Volume: 49, Issue:5

    Topics: Adiponectin; Adipose Tissue; Biopsy; Diabetes Mellitus, Type 2; Gene Expression Regulation; Humans; Infusions, Intravenous; Insect Hormones; Interleukin-6; Male; Middle Aged; Muscle, Skeletal; Oligopeptides; Pyrrolidonecarboxylic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha

2006
Excessive excretion of 5-oxoproline and decreased levels of blood glutathione in type II diabetes mellitus.
    European journal of clinical nutrition, 1990, Volume: 44, Issue:11

    Topics: Adult; Aged; Diabetes Mellitus, Type 2; Glutathione; Humans; Middle Aged; Pyrrolidonecarboxylic Acid; Regression Analysis

1990