pyrrolidonecarboxylic acid has been researched along with Chemical and Drug Induced Liver Injury in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, J; Jang, SI; Kim, SZ; Park, KH; Shin, JH | 1 |
| Imaoka, M; Masubuchi, N; Mizumaki, K; Nishiya, T; Okazaki, O | 1 |
| Geenen, S; Guallar-Hoyas, C; Kenna, JG; Kolaja, KL; Michopoulos, F; Thomas, P; Westerhoff, HV; Wilson, ID | 1 |
| Bukshuk, AA; Maslovskiĭ, LV; Minushkin, ON | 1 |
| Makino, I; Nakamura, K; Sato, Y; Terano, A; Yoneda, M | 1 |
| Kono, T; Nakamura, K; Sato, Y; Terano, A; Watanobe, H; Yokohama, S; Yoneda, M | 1 |
| Farrant, RD; Holmes, E; Nicholson, JK; Waterfield, CJ; Waters, NJ | 1 |
| Bradford, BU; Brenner, D; Enomoto, N; Forman, D; Frey, W; Iimuro, Y; Kono, H; Nakagami, M; Rusyn, I; Thurman, RG; Yamashina, S | 1 |
| Nami, R | 1 |
| Huang, HS; Jurima-Romet, M | 1 |
| Boyd, MR; Ravindranath, V | 1 |
11 other study(ies) available for pyrrolidonecarboxylic acid and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
The ameliorative effects of L-2-oxothiazolidine-4-carboxylate on acetaminophen-induced hepatotoxicity in mice.
Topics: Acetaminophen; Alanine Transaminase; Aldehydes; Analgesics, Non-Narcotic; Animals; Antioxidants; Apoptosis; Aspartate Aminotransferases; Caspase 3; Chemical and Drug Induced Liver Injury; DNA Fragmentation; Glutathione; Glutathione Peroxidase; Liver; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Necrosis; Oxidative Stress; Pyrrolidonecarboxylic Acid; Thiazolidines; Tyrosine | 2013 |
Promising toxicological biomarkers for the diagnosis of liver injury types: Bile acid metabolic profiles and oxidative stress marker as screening tools in drug development.
Topics: 1-Naphthylisothiocyanate; Animals; Bile Acids and Salts; Biomarkers; Chemical and Drug Induced Liver Injury; Cholestasis; Cytochrome P-450 Enzyme System; Drug Evaluation, Preclinical; Gene Expression Regulation; Liver; Male; Metabolome; Oxidative Stress; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley | 2016 |
HPLC-MS/MS methods for the quantitative analysis of 5-oxoproline (pyroglutamate) in rat plasma and hepatic cell line culture medium.
Topics: Animals; Biomarkers; Calibration; Cell Line; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Culture Media; Epithelial Cells; Humans; Liver; Male; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2011 |
[The use of hepatic protectors in clinical practice].
Topics: Amino Acids; Chemical and Drug Induced Liver Injury; Cytoprotection; Drug Combinations; Flavonoids; Hepatocytes; Humans; Liver; Phosphatidylcholines; Protective Agents; Pyridoxine; Pyrrolidonecarboxylic Acid; Ursodeoxycholic Acid | 2012 |
Protective effect of central thyrotropin-releasing hormone on carbon tetrachloride-induced acute hepatocellular necrosis in rats.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Atropine; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Enzyme Inhibitors; Indomethacin; Injections, Intraventricular; Liver; Liver Diseases; Male; Necrosis; NG-Nitroarginine Methyl Ester; Oxidopamine; Parasympatholytics; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Sympatholytics; Thyrotropin-Releasing Hormone; Vagotomy | 2003 |
Involvement of calcitonin gene-related peptide and capsaicin-sensitive afferents in central thyrotropin-releasing hormone-induced hepatic cytoprotection.
Topics: Animals; Aspartate Aminotransferases; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Capsaicin; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cisterna Magna; Injections; Liver; Liver Function Tests; Male; Neurons, Afferent; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Thyrotropin-Releasing Hormone | 2003 |
Integrated metabonomic analysis of bromobenzene-induced hepatotoxicity: novel induction of 5-oxoprolinosis.
Topics: Animals; Biomarkers; Blood Proteins; Bromobenzenes; Chemical and Drug Induced Liver Injury; Liver; Magnetic Resonance Spectroscopy; Male; Necrosis; Pyrrolidonecarboxylic Acid; Rats | 2006 |
The glutathione precursor L-2-oxothiazolidine-4-carboxylic acid protects against liver injury due to chronic enteral ethanol exposure in the rat.
Topics: Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Ethanol; Glutathione; Intubation, Gastrointestinal; Kupffer Cells; Liver; Liver Diseases; Male; Necrosis; NF-kappa B; Prodrugs; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; RNA, Messenger; Thiazoles; Thiazolidines; Time Factors; Tumor Necrosis Factor-alpha | 2000 |
[Hepatic damage caused by drugs and evaluation of the therapeutic effectiveness of pyridoxine pyrrolidone carboxylate].
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Female; Hepatitis, Alcoholic; Humans; Liver Diseases; Male; Middle Aged; Pyridoxine; Pyrrolidinones; Pyrrolidonecarboxylic Acid | 1979 |
Enalapril hepatotoxicity in the rat. Effects of modulators of cytochrome P450 and glutathione.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Biotransformation; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enalapril; Enzyme Induction; Glutathione; Inactivation, Metabolic; Liver; Liver Diseases; Male; Necrosis; Pregnenolone Carbonitrile; Protoporphyrins; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred F344; Sulfhydryl Compounds; Thiazoles; Thiazolidines | 1992 |
Effect of modulators of glutathione synthesis on the hepatotoxicity of 2-methylfuran.
Topics: Alanine Transaminase; Animals; Antimetabolites; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cystine; Drug Interactions; Furans; Glutathione; Male; Maleates; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1991 |