pyrrolidonecarboxylic acid has been researched along with Alcohol Abuse in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (18.75) | 18.7374 |
| 1990's | 5 (31.25) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 4 (25.00) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Addolorato, G; Mirijello, A | 1 |
| Borro, P; Leone, S; Testino, G | 1 |
| Goh, ET; Morgan, MY | 1 |
| Fan, X; Guidot, DM; Joshi, PC; Koval, M | 1 |
| Addolorato, G; Caputo, F; Ferrulli, A; Kenna, GA; Leggio, L; Swift, RM; Zywiak, WH | 1 |
| Blázovics, A; Fehér, J; Váli, L | 1 |
| Choi, JH; Ki, SH; Kim, CW; Kim, SG | 1 |
| Brown, LA; Guidot, DM; Otis, JS | 1 |
| Calabrese, V; Ragusa, N; Rizza, V | 1 |
| Breda, A; Dotta, C; Gelso, E; Moretto, F; Pace, M; Rizzo, A; Sanzuol, F; Tossani, C | 1 |
| Brú, C; Caballería, J; Caballería, L; Clemente, G; García Plaza, A; Mercader, J; Parés, A; Rodés, J; Rodrigo, L | 1 |
| Iakovlev, VA | 1 |
| Corsini, G; Gelso, E; Giuliano, G | 1 |
| Antonini, M; Botti, P; Caramelli, L; Moroni, F; Palmerani, B; Pellegrini-Giampietro, DE; Peruzzi, S; Pistelli, A; Valenza, T; Zorn, AM | 1 |
| Carboni, MA; Corsa, R | 1 |
| Calabrese, V; de Bernardis, E; Rizza, V | 1 |
2 review(s) available for pyrrolidonecarboxylic acid and Alcohol Abuse
| Article | Year |
|---|---|
Review article: pharmacotherapy for alcohol dependence - the why, the what and the wherefore.
Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Baclofen; Disulfiram; Drug Combinations; Fructose; Humans; Naltrexone; Polymorphism, Single Nucleotide; Pyridoxine; Pyrrolidonecarboxylic Acid; Taurine; Topiramate; Treatment Outcome | 2017 |
[The therapeutic effect of metadoxine on alcoholic and non-alcoholic steatohepatitis].
Topics: Alcohol Deterrents; Alcoholic Intoxication; Alcoholism; Drug Combinations; Fatty Liver; Fatty Liver, Alcoholic; Glutathione; Hepatitis; Hepatitis, Alcoholic; Humans; Pyridoxine; Pyrrolidonecarboxylic Acid; Quality of Life | 2005 |
4 trial(s) available for pyrrolidonecarboxylic acid and Alcohol Abuse
| Article | Year |
|---|---|
[Therapeutic use of metadoxine in chronic alcoholism. Double blind study of patients in a department of general medicine].
Topics: Alcoholic Intoxication; Alcoholism; Double-Blind Method; Drug Combinations; Drug Evaluation; Female; Hospital Departments; Humans; Italy; Male; Middle Aged; Pyridoxine; Pyrrolidonecarboxylic Acid; Substance Withdrawal Syndrome | 1993 |
Metadoxine accelerates fatty liver recovery in alcoholic patients: results of a randomized double-blind, placebo-control trial. Spanish Group for the Study of Alcoholic Fatty Liver.
Topics: Adult; Alanine Transaminase; Alcoholism; Aspartate Aminotransferases; Bilirubin; Double-Blind Method; Drug Combinations; Fatty Liver, Alcoholic; Female; gamma-Glutamyltransferase; Humans; Liver; Liver Function Tests; Male; Middle Aged; Placebos; Pyridoxine; Pyrrolidonecarboxylic Acid; Ultrasonography | 1998 |
[The treatment of alcoholism with metadoxil].
Topics: Adult; Alcohol Deterrents; Alcoholism; Drug Combinations; Drug Therapy, Combination; Ethanol; Humans; Male; Middle Aged; Pyridoxine; Pyrrolidonecarboxylic Acid; Substance Withdrawal Syndrome; Time Factors | 1999 |
[Effects of metadoxine on main biohumoral changes induced by chronic alcoholism].
Topics: Adult; Aged; Alcoholism; Drug Combinations; Female; Humans; Liver; Liver Diseases, Alcoholic; Liver Function Tests; Male; Middle Aged; Pyridoxine; Pyrrolidonecarboxylic Acid; Time Factors | 1992 |
10 other study(ies) available for pyrrolidonecarboxylic acid and Alcohol Abuse
| Article | Year |
|---|---|
Treatment of acute alcohol intoxication: The role of metadoxine.
Topics: Alcoholic Intoxication; Alcoholism; Drug Combinations; Humans; Pyridoxine; Pyrrolidonecarboxylic Acid | 2023 |
Liver Disease and Hepatocellular Carcinoma in Alcoholics: The Role of Anticraving Therapy.
Topics: Acamprosate; Alcohol Deterrents; Alcoholics; Alcoholism; Baclofen; Carcinoma, Hepatocellular; Drug Combinations; Humans; Liver Cirrhosis; Liver Neoplasms; Pyridoxine; Pyrrolidonecarboxylic Acid; Risk Factors; Taurine | 2016 |
Chronic alcohol ingestion exacerbates lung epithelial barrier dysfunction in HIV-1 transgenic rats.
Topics: Alcoholism; Animals; Antioxidants; Central Nervous System Depressants; Comorbidity; Disease Models, Animal; Drug Evaluation, Preclinical; Epithelial Cells; Epithelium; Ethanol; Glutathione; HIV Envelope Protein gp120; HIV Infections; HIV-1; Lung; Lung Diseases; Male; Membrane Proteins; NF-E2-Related Factor 2; Occludin; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred F344; Rats, Transgenic; Thiazolidines; Tight Junctions; Time Factors | 2011 |
Preliminary findings on the use of metadoxine for the treatment of alcohol dependence and alcoholic liver disease.
Topics: Adult; Alcohol Deterrents; Alcoholism; Dose-Response Relationship, Drug; Drug Combinations; Female; Follow-Up Studies; Humans; Liver Diseases, Alcoholic; Male; Middle Aged; Pyridoxine; Pyrrolidonecarboxylic Acid; Retrospective Studies | 2011 |
Combined metadoxine and garlic oil treatment efficaciously abrogates alcoholic steatosis and CYP2E1 induction in rat liver with restoration of AMPK activity.
Topics: Adenylate Kinase; Alcoholism; Allyl Compounds; Animals; Cytochrome P-450 CYP2E1; Drug Combinations; Enzyme Induction; Fatty Liver; Liver; Pyridoxine; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Sulfides; Triglycerides | 2007 |
Oxidant-induced atrogin-1 and transforming growth factor-beta1 precede alcohol-related myopathy in rats.
Topics: Alcoholism; Animals; Antioxidants; Biomarkers; Central Nervous System Depressants; Disease Models, Animal; Disease Progression; Ethanol; Glutathione; Male; Muscle Proteins; Muscle, Skeletal; Muscular Atrophy; Muscular Diseases; Oxidants; Oxidation-Reduction; Oxidative Stress; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; RNA, Messenger; SKP Cullin F-Box Protein Ligases; Thiazolidines; Transforming Growth Factor beta1; Up-Regulation | 2007 |
Effect of pyrrolidone carboxylate (PCA) and pyridoxine on liver metabolism during chronic ethanol intake in rats.
Topics: Alcoholism; Animals; Drug Therapy, Combination; Glutathione; Liver; Male; Nucleotides; Pyridines; Pyridoxine; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Tryptophan Oxygenase | 1995 |
Pyrrolidone carboxylic acid in acute and chronic alcoholism. Preclinical and clinical studies.
Topics: Alcoholic Intoxication; Alcoholism; Animals; Ethanol; Female; gamma-Aminobutyric Acid; Guinea Pigs; Humans; Male; Pyrrolidinones; Pyrrolidonecarboxylic Acid; Rats | 1989 |
[Therapeutic use of metadoxine in alcohol-related mental and behavioral disorders].
Topics: Adult; Aged; Alcoholism; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Lorazepam; Male; Mental Disorders; Middle Aged; Pyridoxine; Pyrrolidinones; Pyrrolidonecarboxylic Acid; Social Behavior Disorders | 1987 |
[Metadoxine in the control of oxidative stress caused by acute and chronic ethanol poisoning].
Topics: Alcohol Dehydrogenase; Alcoholic Intoxication; Alcoholism; Aldehyde Dehydrogenase; Animals; Drug Combinations; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Liver; Oxidation-Reduction; Pyridoxine; Pyrrolidinones; Pyrrolidonecarboxylic Acid; Rats | 1986 |