pyrrolidine dithiocarbamate has been researched along with Innate Inflammatory Response in 53 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (11.32) | 18.2507 |
| 2000's | 15 (28.30) | 29.6817 |
| 2010's | 28 (52.83) | 24.3611 |
| 2020's | 4 (7.55) | 2.80 |
| Authors | Studies |
|---|---|
| Aulaskari, PH; Goulas, A; Haukka, M; Moilanen, E; Moilanen, LJ; Nieminen, RM; Sareila, O; Timonen, JM; Vainiotalo, P | 1 |
| Amorim, RC; Cunha, FQ; Cunha, TM; França, RO; Lopes, AH; Pohlit, AM; Silva, EC; Silva, RL; Vieira, SM | 1 |
| Guo, YQ; Liu, Q; Xue, X; Yang, DP; Yin, S; Zhao, JJ; Zhao, ZM; Zhu, LP | 1 |
| Gao, ZF; Hou, GG; Meng, QG; Sun, Y; Wang, CH; Xin, WY; Yan, WB; Yao, BR | 1 |
| Kim, SS; Seo, SR; Shin, JH | 1 |
| Bishayi, B; Dutta, P | 1 |
| Duan, J; Li, T; Ma, JY; Wang, H; Wu, YN; Zhai, SS | 1 |
| Feng, W; Han, R; Liu, ZQ; Miao, YZ; Qin, ZH; Wang, Y; Zhang, X | 1 |
| Ahn, G; Cho, SH; Eom, CY; Heo, SJ; Jeon, YJ; Jeong, MS; Kim, KN; Kim, SY; Ko, EY; Kwon, SH; Lee, KP; Lee, W | 1 |
| Bagchi, A; Biswas, R | 1 |
| Cheng, X; Dong, R; Li, J; Li, N; Li, X; Liu, T; Wang, Q; Yang, Q; Zhang, L; Zhang, Y; Zhao, H | 1 |
| Chen, Y; Geng, S; Jiang, Y; Li, X; Li, Y; Meng, Y; Wang, S; Wang, X; Wu, J; Xie, C; Yang, X; Zhong, C; Zhu, J; Zhu, W | 1 |
| Abe, K; Ishikawa, M; Ishikawa, T; Oka, M; Saku, K; Shinoda-Sakamoto, M; Sunagawa, K; Tsutsui, H; Watanabe, T; Yoshida, K | 1 |
| Feng, J; Ge, CX; Gu, TT; Hu, LF; Huang, P; Li, Q; Lou, DS; Qin, YT; Tan, J; Xu, MX | 1 |
| Du, J; Ma, JH; Pan, WZ; Zhang, LY | 1 |
| Bai, L; Ji, M; Lin, R; Lu, Y; Qiao, H; Ren, F; Wang, W; Yang, L; Zhang, J | 1 |
| Gong, ZJ; Han, XQ; Li, X; Wang, LK; Wang, LW; Yang, F; Zhang, H | 1 |
| Alhussaini, AA; Cool, CD; Farkas, D; Farkas, L; Kraskauskas, D; Kraskauskiene, V; Natarajan, R; Nicolls, MR | 1 |
| Choi, IW; Choi, YH; Dilshara, MG; Jayasooriya, RG; Kang, CH; Kim, GY; Lee, HJ; Lee, KT | 1 |
| Bhat, OM; Dhawan, V; Giridharan, NV; Kaul, D; Kumar, MJ; Kumar, PU | 1 |
| Hall, RP; Jin, JY; Qin, X; Streilein, R; Wu, J; Zhang, JY; Zhang, X | 1 |
| Alpers, CE; Anderberg, RJ; Cooney, SK; Hudkins, KL; Leboeuf, RC; Meek, RL; Tuttle, KR | 1 |
| Cai, JC; Cathopoulis, T; Han, R; Li, X; Liu, F; Liu, GY; Lu, K; Luo, G; Peng, B; Shi, SL; Yang, L | 1 |
| Li, Z; Wei, M; Xiao, L; Yang, Z | 1 |
| Alves-Filho, JC; Borghi, SM; Carvalho, TT; Casagrande, R; Cunha, FQ; Cunha, TM; Fattori, V; Pinho-Ribeiro, FA; Staurengo-Ferrari, L; Verri, WA; Zarpelon, AC | 1 |
| Chen, L; Qin, C; Wang, XF; Xiao, YB; Zhong, QJ | 1 |
| Kang, S; Lee, WH; Lee, YW; Vlachos, PP | 1 |
| Chen, X; Chen, Z; Huang, J; Lei, T; Long, H; Long, Q; Peng, Y; Yang, Z; Zhang, J; Zhou, L | 1 |
| Wang, Y; Xue, S; Yang, W; Zhang, F | 1 |
| Feng, B; Guo, YH; Luo, ZF; Mu, J; Qi, W; Ye, ZL; Yuan, FH; Zeng, W; Zhang, YQ | 1 |
| Chen, JM; Lui, RC; Zhang, XH; Zhou, CB; Zhuang, J | 1 |
| Moskalev, AA; Plyusnina, EN; Shaposhnikov, MV | 1 |
| Chen, P; Chen, W; Shi, Q; Wang, H; Wang, Y; Xu, X | 1 |
| Nath, C; Niranjan, R; Shukla, R | 1 |
| Britti, D; Cuzzocrea, S; Di Paola, R; Genovese, T; Mazzon, E; Serraino, I; Siriwardena, A; Thiemerman, C; Virlos, I | 1 |
| Cacciola, F; Cardali, S; Conti, A; Cuzzocrea, S; Di Paola, R; Genovese, T; La Rosa, G; La Torre, D | 1 |
| Hodnett, M; Pespeni, M; Pittet, JF | 1 |
| Jana, M; Pahan, K | 1 |
| Asai, T; Iwai, T; Kaneda, N; Komiya, T; Kuwabara, N; Miura, K; Nakatani, T; Tamada, S; Teramoto, K; Uchida, J; Yukimura, T | 1 |
| Menge, C; Permana, PA; Reaven, PD | 1 |
| Cechetto, DF; Cheng, G; Hachinski, V; Whitehead, SN | 1 |
| Antunes, GR; Fujihara, CK; Malheiros, DM; Mattar, AL; Vieira, JM; Zatz, R | 1 |
| Fisher, BJ; Fowler, AA; Natarajan, R | 1 |
| Jia, YT; Ma, B; Tang, HT; Wang, Y; Wei, W; Xia, ZF; Xu, Y | 1 |
| Hirata, I; Inoue, T; Katsu, K; Murano, M; Murano, N; Nishikawa, T; Toshina, K; Wang, FY; Yasumoto, S | 1 |
| Lin, JC; Mar, EC; Medford, RM; Offermann, MK; Shaw, R; Yang, J | 1 |
| Heese, K; Hock, C; Otten, U | 1 |
| Barascud, Y; Bascands, JL; Bataillé, E; Gauthier, F; Girolami, JP; Hirtz, C; Marin Castaño, ME; Pecher, C; Pesquero, JB; Schanstra, JP | 1 |
| Khan, M; Pahan, K; Singh, AK; Singh, I | 1 |
| Boyle, EM; Canty, TG; Chi, E; Kovacich, JC; Morgan, EN; Pohlman, TH; Verrier, ED | 1 |
| Chen, Z; Dong, G; Kato, T; Van Waes, C | 1 |
| Hennig, B; Kühn, H; Lee, YW; Neish, AS; Toborek, M | 1 |
| Colville-Nash, PR; Gilroy, DW; Lawrence, T; Willoughby, DA | 1 |
2 review(s) available for pyrrolidine dithiocarbamate and Innate Inflammatory Response
| Article | Year |
|---|---|
In vivo stress preconditioning.
Topics: Animal Experimentation; Animals; Animals, Laboratory; Antioxidants; Blotting, Western; Electrophoresis, Polyacrylamide Gel; Fever; Heat-Shock Proteins; Hot Temperature; HSP72 Heat-Shock Proteins; Humans; Inflammation; Lung; Lung Injury; Mice; Molecular Chaperones; Nitric Oxide; Oxidative Stress; Pyrrolidines; Rats; Research Design; Stress, Physiological; Thiocarbamates | 2005 |
Molecular mechanisms and therapeutic strategies of chronic renal injury: the role of nuclear factor kappaB activation in the development of renal fibrosis.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents; Carbon; Disease Models, Animal; Fibrosis; Inflammation; Kidney Diseases; NF-kappa B; Oxides; Pyrrolidines; Rats; Renin-Angiotensin System; Thiocarbamates | 2006 |
51 other study(ies) available for pyrrolidine dithiocarbamate and Innate Inflammatory Response
| Article | Year |
|---|---|
Synthesis and anti-inflammatory effects of a series of novel 7-hydroxycoumarin derivatives.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Cell Line; Crystallography, X-Ray; Cyclooxygenase 2; Enzyme-Linked Immunosorbent Assay; Inflammation; Interleukin-6; Lipopolysaccharides; Mice; Nitric Oxide Synthase Type II; Structure-Activity Relationship; Umbelliferones | 2011 |
The quassinoid isobrucein B reduces inflammatory hyperalgesia and cytokine production by post-transcriptional modulation.
Topics: Animals; Anti-Inflammatory Agents; Brazil; Carrageenan; Cyclooxygenase 2; Cytokines; Dinoprostone; Hyperalgesia; I-kappa B Proteins; Inflammation; Interleukin-1beta; Lipopolysaccharides; Macrophages; Male; Mice; Mitogen-Activated Protein Kinases; Molecular Structure; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Peroxidase; Plants, Medicinal; Quassins; Simaroubaceae; Tumor Necrosis Factor-alpha | 2015 |
Chlojaponilactone B from Chloranthus japonicus: Suppression of Inflammatory Responses via Inhibition of the NF-κB Signaling Pathway.
Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Cytokines; Inflammation; Inflammation Mediators; Interleukin-6; Lipopolysaccharides; Macrophages; Mice; Molecular Structure; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Sesquiterpenes; Signal Transduction; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2016 |
Discovery of novel NF-кB inhibitor based on scaffold hopping: 1,4,5,6,7,8-hexahydropyrido[4,3-d]pyrimidine.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line; Dose-Response Relationship, Drug; Drug Design; Humans; Inflammation; Lipopolysaccharides; Liver Neoplasms; MAP Kinase Signaling System; Mice; Molecular Docking Simulation; NF-kappa B; Phosphorylation; Piperidones; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Structure-Activity Relationship; Tumor Necrosis Factor-alpha | 2020 |
Pyrrolidine Dithiocarbamate Suppresses
Topics: Animals; Anti-Inflammatory Agents; Base Composition; Cytokines; Dermatitis; Inflammasomes; Inflammation; Interleukin-6; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; NLR Proteins; Phylogeny; RNA, Ribosomal, 16S; Sequence Analysis, DNA | 2023 |
Pyrrolidine dithiocarbamate in combination with L-N-monomethyl arginine alleviates Staphylococcus aureus infection via regulation of CXCL8/CXCR1 axis in peritoneal macrophages in vitro.
Topics: Animals; Antioxidants; Arginase; Cytokines; Hydrogen Peroxide; Inflammation; Macrophages, Peritoneal; Mice; NF-kappa B; omega-N-Methylarginine; Reactive Oxygen Species; Receptors, Interleukin-8A; Staphylococcal Infections; Staphylococcus aureus | 2023 |
Dapk1 improves inflammation, oxidative stress and autophagy in LPS-induced acute lung injury via p38MAPK/NF-κB signaling pathway.
Topics: Acute Lung Injury; Animals; Autophagy; Death-Associated Protein Kinases; Imidazoles; Inflammation; Lipopolysaccharides; Lung; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pyridines; Pyrrolidines; Signal Transduction; Thiocarbamates | 2020 |
Microglia activation contributes to quinolinic acid-induced neuronal excitotoxicity through TNF-α.
Topics: Animals; Apoptosis; Cell Survival; Gene Expression Regulation; Inflammation; Microglia; Minocycline; Neurons; Neurotoxins; NF-kappa B; Primary Cell Culture; Pyrrolidines; Quinolinic Acids; Rats; Thiocarbamates; Tumor Necrosis Factor-alpha | 2017 |
The roles of NF-κB and ROS in regulation of pro-inflammatory mediators of inflammation induction in LPS-stimulated zebrafish embryos.
Topics: Acetylcysteine; Animals; Embryo, Nonmammalian; Fish Diseases; Fish Proteins; Gene Expression Regulation; Inflammation; Inflammation Mediators; Lipopolysaccharides; NF-kappa B; Pyrrolidines; Reactive Oxygen Species; Thiocarbamates; Zebrafish | 2017 |
Inhibition of TRAF6-Ubc13 interaction in NFkB inflammatory pathway by analyzing the hotspot amino acid residues and protein-protein interactions using molecular docking simulations.
Topics: Amino Acids; Computational Biology; Humans; Inflammation; Intracellular Signaling Peptides and Proteins; Ligands; Molecular Docking Simulation; NF-kappa B; Protein Binding; Protein Interaction Maps; Pyrrolidines; Thiocarbamates; TNF Receptor-Associated Factor 6; Ubiquitin-Conjugating Enzymes | 2017 |
Inhibitive Effect of Resveratrol on the Inflammation in Cultured Astrocytes and Microglia Induced by Aβ
Topics: Active Transport, Cell Nucleus; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Astrocytes; Cells, Cultured; Dose-Response Relationship, Drug; Estradiol; Estrogens; Inflammation; Microglia; NF-kappa B; Peptide Fragments; Pyrrolidines; Rats; Resveratrol; Thiocarbamates; Transcription Factor RelA | 2018 |
Curcumin suppresses JNK pathway to attenuate BPA-induced insulin resistance in LO2 cells.
Topics: Anthracenes; Benzhydryl Compounds; Cell Line; Curcumin; Enzyme Activation; Humans; Imidazoles; Inflammation; Insulin Resistance; MAP Kinase Signaling System; NF-kappa B; Oxidative Stress; Phenols; Pyridines; Pyrrolidines; Thiocarbamates | 2018 |
Inhibition of TLR9-NF-κB-mediated sterile inflammation improves pressure overload-induced right ventricular dysfunction in rats.
Topics: Animals; Anti-Inflammatory Agents; Fibrosis; Hypertrophy, Right Ventricular; Inflammation; Inflammation Mediators; Macrophages; Male; NF-kappa B; Pyrrolidines; Rats, Sprague-Dawley; Signal Transduction; Thiocarbamates; Toll-Like Receptor 9; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Pressure; Ventricular Remodeling | 2019 |
Prolonged PM2.5 exposure elevates risk of oxidative stress-driven nonalcoholic fatty liver disease by triggering increase of dyslipidemia.
Topics: Acetylcysteine; Air Pollutants; Animals; Dyslipidemias; Hepatocytes; Humans; Inflammation; Insulin Resistance; Lipid Metabolism; Liver; Metabolic Syndrome; Mice; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Particulate Matter; Pyrrolidines; Signal Transduction; Thiocarbamates | 2019 |
The roles of NF-kB in the development of lung injury after one-lung ventilation.
Topics: Animals; Blood Gas Analysis; Cytokines; Hemodynamics; Inflammation; Lung; Lung Injury; NF-kappa B; One-Lung Ventilation; Pyrrolidines; Rats; Rats, Sprague-Dawley; Respiratory Mechanics; Thiocarbamates | 2018 |
The protective effect of fenofibrate against TNF-α-induced CD40 expression through SIRT1-mediated deacetylation of NF-κB in endothelial cells.
Topics: Acetylation; Antioxidants; Benzamides; CD40 Antigens; Cells, Cultured; Fenofibrate; Human Umbilical Vein Endothelial Cells; Humans; Hypolipidemic Agents; Inflammation; Naphthols; Niacinamide; Oxazoles; PPAR alpha; Pyrrolidines; RNA Interference; RNA, Small Interfering; Signal Transduction; Sirtuin 1; Thiocarbamates; Transcription Factor RelA; Tumor Necrosis Factor-alpha; Tyrosine; Up-Regulation | 2014 |
Inhibitions of NF-κB and TNF-α result in differential effects in rats with acute on chronic liver failure induced by d-Gal and LPS.
Topics: Acute-On-Chronic Liver Failure; Animals; Anti-Inflammatory Agents; Antibodies; Cell Line, Tumor; Cell Survival; Cytokines; Female; Galactosamine; HMGB1 Protein; Humans; Inflammation; Lipopolysaccharides; Pyrrolidines; Rats; Rats, Wistar; Signal Transduction; Thiocarbamates; Toll-Like Receptor 4; Transcription Factor RelA; Tumor Necrosis Factor-alpha; U937 Cells | 2014 |
Nuclear factor κB inhibition reduces lung vascular lumen obliteration in severe pulmonary hypertension in rats.
Topics: Animals; Apoptosis; CD4-Positive T-Lymphocytes; Familial Primary Pulmonary Hypertension; Humans; Hypertension, Pulmonary; Hypoxia; Indoles; Inflammation; Interleukin-6; Leukocyte Common Antigens; Lung; NF-kappa B; Pulmonary Artery; Pyrroles; Pyrrolidines; Rats; Signal Transduction; Thiocarbamates; Time Factors | 2014 |
Isobutyrylshikonin inhibits lipopolysaccharide-induced nitric oxide and prostaglandin E2 production in BV2 microglial cells by suppressing the PI3K/Akt-mediated nuclear transcription factor-κB pathway.
Topics: Antioxidants; Cell Line; Central Nervous System Diseases; Cyclooxygenase 2; Dinoprostone; Down-Regulation; Inflammation; Inflammation Mediators; Lipopolysaccharides; Lithospermum; Macrophages; Microglia; Naphthoquinones; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphatidylinositol 3-Kinases; Phosphorylation; Phytotherapy; Plant Extracts; Proto-Oncogene Proteins c-akt; Pyrrolidines; Signal Transduction; Thiocarbamates | 2014 |
Interleukin-18-induced atherosclerosis involves CD36 and NF-κB crosstalk in Apo E-/- mice.
Topics: Animals; CD36 Antigens; Coronary Artery Disease; Disease Models, Animal; Down-Regulation; Inflammation; Interleukin-18; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred Strains; Pyrrolidines; RNA, Messenger; Thiocarbamates | 2015 |
RNA-Seq and ChIP-Seq reveal SQSTM1/p62 as a key mediator of JunB suppression of NF-κB-dependent inflammation.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Adhesion; Cell Proliferation; Chemokine CCL2; Chemokine CXCL10; Chromatin Immunoprecipitation; Cytokines; Epidermis; Gene Deletion; Genes, Reporter; Heat-Shock Proteins; HEK293 Cells; Humans; Inflammation; Keratinocytes; Mice; Mutation; NF-kappa B; Oligonucleotide Array Sequence Analysis; Pyrrolidines; Regeneration; Sequence Analysis, RNA; Sequestosome-1 Protein; Skin Physiological Phenomena; Thiocarbamates; Transcription Factors | 2015 |
Serum amyloid A and inflammation in diabetic kidney disease and podocytes.
Topics: Animals; Antioxidants; Cells, Cultured; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Gene Expression; Humans; Immunohistochemistry; Inflammation; Kidney; Kidney Diseases; Mice, Inbred C57BL; NF-kappa B; Podocytes; Pyrrolidines; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Serum Amyloid A Protein; Thiocarbamates | 2015 |
Dynamic metabolic change is indicative of inflammation-induced transformation of hepatic cells.
Topics: Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Chemical and Drug Induced Liver Injury; Cluster Analysis; Diethylnitrosamine; Gene Expression Regulation, Neoplastic; Hepatitis, Animal; Humans; Inflammation; Lipopolysaccharides; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Metabolome; Metabolomics; Mice, Inbred C57BL; Pyrrolidines; Reverse Transcriptase Polymerase Chain Reaction; Thiocarbamates | 2015 |
Effects of ROS-relative NF-κB signaling on high glucose-induced TLR4 and MCP-1 expression in podocyte injury.
Topics: Acetylcysteine; Animals; Cell Line, Transformed; Chemokine CCL2; Gene Expression Regulation; Glucose; Inflammation; Mice; NF-kappa B; Podocytes; Pyrrolidines; Reactive Oxygen Species; Signal Transduction; Thiocarbamates; Toll-Like Receptor 4 | 2015 |
Pyrrolidine dithiocarbamate inhibits superoxide anion-induced pain and inflammation in the paw skin and spinal cord by targeting NF-κB and oxidative stress.
Topics: Animals; Dose-Response Relationship, Drug; Drug Delivery Systems; Edema; Inflammation; Male; Mice; NF-kappa B; Oxidative Stress; Pain; Pyrrolidines; Spinal Cord; Superoxides; Thiocarbamates | 2016 |
Anti-inflammatory effect of erythropoietin pretreatment on cardiomyocytes with hypoxia/reoxygenation injury and the possible mechanism.
Topics: Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Blotting, Western; Cells, Cultured; Electrophoretic Mobility Shift Assay; Erythropoietin; Hypoxia; Inflammation; Myocytes, Cardiac; NF-kappa B; Pyrrolidines; Random Allocation; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; Thiocarbamates; Tumor Necrosis Factor-alpha | 2008 |
A novel in vitro ischemia/reperfusion injury model.
Topics: Antioxidants; Cell Culture Techniques; Cell Shape; Cells, Cultured; Endothelial Cells; Gene Expression Regulation; Hemorheology; Humans; Inflammation; Inflammation Mediators; Microcirculation; Oxidative Stress; Pyrrolidines; Regional Blood Flow; Reperfusion Injury; Stress, Mechanical; Thiocarbamates; Time Factors; Up-Regulation | 2009 |
Resistin up-regulates COX-2 expression via TAK1-IKK-NF-kappaB signaling pathway.
Topics: Animals; Cell Line; Cyclooxygenase 2; I-kappa B Kinase; Inflammation; Lipopolysaccharides; Macrophages; MAP Kinase Kinase Kinases; Mice; Mutation; Pyrrolidines; Recombinant Proteins; Resistin; Signal Transduction; Thiocarbamates; Transcription Factor RelA; Transfection; Up-Regulation | 2010 |
Nicotine induces pro-inflammatory response in aortic vascular smooth muscle cells through a NFκB/osteopontin amplification loop-dependent pathway.
Topics: Aorta; Cells, Cultured; Chemokine CCL2; Humans; Inflammation; Interleukin-6; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Nicotine; Osteopontin; Pyrrolidines; RNA Interference; RNA, Small Interfering; Smoking; Thiocarbamates | 2012 |
Uraemic serum induces dysfunction of vascular endothelial cells: role of ubiquitin-proteasome pathway.
Topics: Animals; Apoptosis; Cell Cycle; Cell Nucleus; Cell Proliferation; Cells, Cultured; DNA-Binding Proteins; Endothelial Cells; Inflammation; Leupeptins; NF-kappa B; Nitric Oxide; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Protein Transport; Pyrrolidines; Rabbits; Signal Transduction; Thiocarbamates; Tumor Necrosis Factor-alpha; Ubiquitin; Ubiquitin-Activating Enzymes; Uremia | 2011 |
Decrease in inflammatory response does not prevent placental dysfunction after fetal cardiac bypass in goats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents; Cardiac Surgical Procedures; Electrophoretic Mobility Shift Assay; Endothelin-1; Female; Fetal Blood; Fetal Heart; Gestational Age; Goats; Inflammation; Inflammation Mediators; Interleukin-6; NF-kappa B; Nitric Oxide; Placenta; Placenta Diseases; Placental Circulation; Pregnancy; Pyrrolidines; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiocarbamates; Thromboxane B2; Tumor Necrosis Factor-alpha; Vascular Resistance | 2012 |
Effect of PARP-1 overexpression and pharmacological inhibition of NF-kB on the lifespan of Drosophila melanogaster.
Topics: Animals; Cellular Senescence; DNA Damage; DNA Repair; Drosophila melanogaster; Drosophila Proteins; Female; Fertility; Gene Expression; Inflammation; Life Expectancy; Male; Motor Activity; NF-kappa B; Poly(ADP-ribose) Polymerases; Pyrrolidines; Thiocarbamates | 2011 |
Quercetin suppresses NF-κB and MCP-1 expression in a high glucose-induced human mesangial cell proliferation model.
Topics: Cell Cycle Checkpoints; Cell Line; Cell Proliferation; Chemokine CCL2; Diabetes Mellitus; Diabetic Nephropathies; Glucose; Humans; Inflammation; Kidney; Mesangial Cells; NF-kappa B; Pyrrolidines; Quercetin; Signal Transduction; Thiocarbamates; Transcription Factor RelA | 2012 |
Melatonin attenuated mediators of neuroinflammation and alpha-7 nicotinic acetylcholine receptor mRNA expression in lipopolysaccharide (LPS) stimulated rat astrocytoma cells, C6.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents; Astrocytoma; Cytokines; Inflammation; Lipopolysaccharides; Melatonin; Oxidative Stress; Pyrrolidines; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiocarbamates; Tumor Cells, Cultured | 2012 |
Pyrrolidine dithiocarbamate reduces the severity of cerulein-induced murine acute pancreatitis.
Topics: Amylases; Animals; Antioxidants; Blotting, Western; Ceruletide; Edema; I-kappa B Proteins; Immunohistochemistry; Inflammation; Intercellular Adhesion Molecule-1; Lipase; Lipid Peroxidation; Male; Mice; Necrosis; Neutrophils; NF-kappa B; NF-KappaB Inhibitor alpha; Pancreatitis; Peroxidase; Pyrrolidines; Rats; Thiocarbamates; Tyrosine; Up-Regulation | 2003 |
Inhibition of the nuclear factor-kappaB activation with pyrrolidine dithiocarbamate attenuating inflammation and oxidative stress after experimental spinal cord trauma in rats.
Topics: Analysis of Variance; Animals; Antioxidants; Blotting, Western; Immunoenzyme Techniques; Inflammation; Male; Neutrophils; NF-kappa B; Nitric Oxide Synthase; Oxidative Stress; Photomicrography; Pyrrolidines; Random Allocation; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Statistics, Nonparametric; Thiocarbamates | 2004 |
Redox regulation of cytokine-mediated inhibition of myelin gene expression in human primary oligodendrocytes.
Topics: Acetylcysteine; Animals; Antioxidants; Cells, Cultured; Cytokines; DNA Primers; Dose-Response Relationship, Drug; Down-Regulation; Encephalomyelitis, Autoimmune, Experimental; Female; Gene Expression Regulation; Humans; Hydrogen Peroxide; Inflammation; Interleukin-1; Mice; Multiple Sclerosis; Myelin Basic Protein; Myelin Proteins; Myelin Proteolipid Protein; Myelin Sheath; Myelin-Associated Glycoprotein; Myelin-Oligodendrocyte Glycoprotein; Neuroglia; Oligodendroglia; Oxidants; Oxidation-Reduction; Phosphoric Diester Hydrolases; Proline; Pyrrolidines; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Sulfhydryl Compounds; Thiocarbamates; Time Factors; Tumor Necrosis Factor-alpha | 2005 |
Macrophage-secreted factors induce adipocyte inflammation and insulin resistance.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Cell Line; Chemokine CCL2; Cytokines; Glucose; Humans; Inflammation; Insulin; Insulin Resistance; Intercellular Adhesion Molecule-1; Interleukin-6; Macrophages; Mice; Models, Statistical; NF-kappa B; Obesity; Pyrrolidines; Reverse Transcriptase Polymerase Chain Reaction; RNA; Thiocarbamates; Time Factors; U937 Cells | 2006 |
Effects of pyrrolidine dithiocarbamate on beta-amyloid (25-35)-induced inflammatory responses and memory deficits in the rat.
Topics: Amyloid beta-Peptides; Animals; Brain; Immunohistochemistry; Inflammation; Injections, Intraventricular; Male; Memory Disorders; Neuroprotective Agents; Pyrrolidines; Rats; Rats, Wistar; Thiocarbamates | 2006 |
Chronic inhibition of nuclear factor-kappaB attenuates renal injury in the 5/6 renal ablation model.
Topics: Animals; Body Weight; Immunohistochemistry; Inflammation; Kidney; Kidney Diseases; Macrophages; Male; Nephrectomy; NF-kappa B; Organ Size; Pyrrolidines; Rats; Rats, Wistar; Renal Circulation; Thiocarbamates; Transcription Factor RelA | 2007 |
Hypoxia inducible factor-1 modulates hemin-induced IL-8 secretion in microvascular endothelium.
Topics: Amino Acids, Dicarboxylic; Antioxidants; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Inhibitors; Hemin; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Interleukin-8; Iron; Microcirculation; Procollagen-Proline Dioxygenase; Pyrrolidines; RNA Stability; RNA, Messenger; RNA, Small Interfering; Serum; Signal Transduction; Thiocarbamates; Time Factors; Transcription, Genetic | 2007 |
Sustained activation of nuclear factor-kappaB by reactive oxygen species is involved in the pathogenesis of stress-induced gastric damage in rats.
Topics: Animals; Free Radical Scavengers; Inflammation; Male; NF-kappa B; Oxidative Stress; Pyrrolidines; Random Allocation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Stomach Ulcer; Stress, Psychological; Thiocarbamates | 2007 |
Evaluation of the effect of pyrrolidine dithiocarbamate in suppressing inflammation in mice with dextran sodium sulfate-induced colitis.
Topics: Animals; Antioxidants; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Female; Indicators and Reagents; Inflammation; Injections, Intraperitoneal; Interleukin-1beta; Mice; Mice, Inbred BALB C; NF-kappa B; Pyrrolidines; Severity of Illness Index; Thiocarbamates; Tumor Necrosis Factor-alpha | 2007 |
Antioxidant-sensitive regulation of inflammatory-response genes in Kaposi's sarcoma cells.
Topics: Animals; Antioxidants; Base Sequence; Biopsy; Blotting, Northern; Blotting, Southern; Cells, Cultured; DNA Probes; E-Selectin; Gene Expression Regulation, Viral; HIV Infections; Humans; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-6; Male; Molecular Sequence Data; NF-kappa B; Polymerase Chain Reaction; Pyrrolidines; RNA, Viral; Sarcoma, Kaposi; Skin; Thiocarbamates; Vascular Cell Adhesion Molecule-1 | 1996 |
Inflammatory signals induce neurotrophin expression in human microglial cells.
Topics: Amyloid beta-Peptides; Antioxidants; Brain; Cell Line; Complement C3a; Cytokines; Embryo, Mammalian; Gene Expression Regulation; Humans; Inflammation; Interleukin-1; Microglia; Nerve Growth Factors; Peptide Fragments; Polymerase Chain Reaction; Proto-Oncogene Proteins; Pyrrolidines; Receptor Protein-Tyrosine Kinases; Receptor, Nerve Growth Factor; Receptor, trkA; Receptors, Nerve Growth Factor; Signal Transduction; Thiocarbamates; Tumor Necrosis Factor-alpha | 1998 |
The B1-agonist [des-Arg10]-kallidin activates transcription factor NF-kappaB and induces homologous upregulation of the bradykinin B1-receptor in cultured human lung fibroblasts.
Topics: Amino Acid Sequence; Cell Line; Cholera Toxin; DNA-Binding Proteins; Fibroblasts; Humans; Inflammation; Interleukin-1; Kallidin; Lung; Molecular Sequence Data; NF-kappa B; Proline; Pyrrolidines; Receptor, Bradykinin B1; Receptors, Bradykinin; RNA, Messenger; Thiocarbamates; Transcriptional Activation; Up-Regulation; Virulence Factors, Bordetella | 1998 |
Cytokine-mediated induction of ceramide production is redox-sensitive. Implications to proinflammatory cytokine-mediated apoptosis in demyelinating diseases.
Topics: Acetylcysteine; Adrenoleukodystrophy; Amitrole; Animals; Antioxidants; Apoptosis; Brain; Cells, Cultured; Ceramides; Cytokines; Diamide; DNA Fragmentation; Glutathione; Glutathione Disulfide; Hydrogen Peroxide; Inflammation; Interleukin-1; Multiple Sclerosis; Oxidation-Reduction; Pyrrolidines; Rats; Reactive Oxygen Species; Sphingomyelins; Thiocarbamates; Tumor Necrosis Factor-alpha | 1998 |
Inhibition of nuclear factor-kappa B nuclear localization reduces human E-selectin expression and the systemic inflammatory response.
Topics: Animals; Cell Membrane; Cell Nucleus; E-Selectin; Endothelium, Vascular; Endotoxins; Humans; Inflammation; NF-kappa B; Pyrrolidines; Rabbits; Thiocarbamates; Tissue Distribution; Transcription, Genetic | 1998 |
The host environment promotes the constitutive activation of nuclear factor-kappaB and proinflammatory cytokine expression during metastatic tumor progression of murine squamous cell carcinoma.
Topics: Animals; Carcinoma, Squamous Cell; Cell Nucleus; Cytokines; Cytoplasm; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Genes, Reporter; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; I-kappa B Proteins; Inflammation; Interleukin-1; Interleukin-6; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Transplantation; NF-kappa B; NF-KappaB Inhibitor alpha; Promoter Regions, Genetic; Protease Inhibitors; Pyrrolidines; Recombinant Fusion Proteins; Selection, Genetic; Thiocarbamates; Tosylphenylalanyl Chloromethyl Ketone; Transcription Factor RelA; Transplantation, Heterologous; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1999 |
IL-4-induced oxidative stress upregulates VCAM-1 gene expression in human endothelial cells.
Topics: Acetylcysteine; Arteriosclerosis; Cells, Cultured; Endothelium, Vascular; Genes, Reporter; Humans; Inflammation; Interleukin-4; Oxidative Stress; Promoter Regions, Genetic; Pyrrolidines; Reverse Transcriptase Polymerase Chain Reaction; Sp1 Transcription Factor; Thiocarbamates; Transcription Factors; Transcription, Genetic; Transfection; Umbilical Veins; Up-Regulation; Vascular Cell Adhesion Molecule-1 | 2001 |
Possible new role for NF-kappaB in the resolution of inflammation.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; bcl-2-Associated X Protein; Carrageenan; Cysteine Endopeptidases; Female; Granuloma; Inflammation; Leukocytes; Leupeptins; Male; Mice; Multienzyme Complexes; NF-kappa B; Nitriles; Pleurisy; Proteasome Endopeptidase Complex; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrrolidines; Rats; Sulfones; Thiocarbamates; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Suppressor Protein p53 | 2001 |