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pyrrolidine dithiocarbamate and Breast Cancer

pyrrolidine dithiocarbamate has been researched along with Breast Cancer in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (40.00)29.6817
2010's6 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, NF; Chuang, SK; Lee, YJ; Lin, WL; Tseng, TH1
Cheng, X; He, L; Li, D; Sun, M; Tang, R; Wang, X; Zheng, Y1
Busby, B; Covington, J; Gu, JW; Johnson, JW; Young, E1
Bang, JS; Choi, HM; Kim, KS; Oh, DH; Yang, HI; Yoo, MC1
Dou, QP; Li, L; Liu, X; Wang, F; Wu, S; Yan, B; Zhai, S1
Huang, W; Lin, Q; Wei, H; Yang, C; Zhang, H1
Fu, ZY; Lv, JH; Ma, CY; Wang, T; Yang, DP1
Chen, D; Cui, QC; Daniel, KG; Dou, QP; Miller, FR; Orlu, S1
Bai, J; Gu, P; Margolick, JB; Zhang, H; Zhang, Y; Zhou, J1
Furuta, S; Mason, A; Momand, J; Ortiz, F; Wu, HH; Zhu Sun, X1

Other Studies

10 other study(ies) available for pyrrolidine dithiocarbamate and Breast Cancer

ArticleYear
Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice.
    European journal of medicinal chemistry, 2012, Volume: 56

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Movement; Cell Proliferation; Coumarins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Mice; Mice, Nude; Molecular Structure; Neoplasm Invasiveness; Signal Transduction; Structure-Activity Relationship; Tumor Cells, Cultured

2012
Co-delivery of DOX and PDTC by pH-sensitive nanoparticles to overcome multidrug resistance in breast cancer.
    Colloids and surfaces. B, Biointerfaces, 2019, Sep-01, Volume: 181

    Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Proliferation; Cells, Cultured; Doxorubicin; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; HEK293 Cells; Humans; Hydrodynamics; Hydrogen-Ion Concentration; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Particle Size; Polymers; Pyrrolidines; Surface Properties; Thiocarbamates

2019
Oral administration of pyrrolidine dithiocarbamate (PDTC) inhibits VEGF expression, tumor angiogenesis, and growth of breast cancer in female mice.
    Cancer biology & therapy, 2009, Mar-15, Volume: 8, Issue:6

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Synergism; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; Indoles; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; NF-kappa B; Pyrroles; Pyrrolidines; Thiocarbamates; Tumor Burden; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2

2009
Fetal bovine serum requirement for pyrrolidine dithiocarbamate-induced apoptotic cell death of MCF-7 breast tumor cells.
    European journal of pharmacology, 2010, Dec-15, Volume: 649, Issue:1-3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blood Proteins; Breast Neoplasms; Cattle; Cell Line, Tumor; Cell Survival; Chelating Agents; Culture Media; Dialysis; Enzyme Inhibitors; Female; Fetal Blood; Humans; NF-kappa B; Proteasome Inhibitors; Pyrrolidines; Serum; Thiocarbamates; Zinc

2010
A novel dithiocarbamate analogue with potentially decreased ALDH inhibition has copper-dependent proteasome-inhibitory and apoptosis-inducing activity in human breast cancer cells.
    Cancer letters, 2011, Jan-01, Volume: 300, Issue:1

    Topics: Aldehyde Dehydrogenase; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Copper; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Proteasome Inhibitors; Pyrrolidines; Thiocarbamates

2011
[Effect of combined use of PDTC and paclitaxel on proliferation and invasion of human breast cancer cell line MCF-7].
    Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2010, Volume: 27, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Female; Humans; Neoplasm Invasiveness; NF-kappa B; Paclitaxel; Pyrrolidines; Thiocarbamates

2010
Tissue inhibitor of metalloproteinase-1 decreased chemosensitivity of MDA-435 breast cancer cells to chemotherapeutic drugs through the PI3K/AKT/NF-кB pathway.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2011, Volume: 65, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Chromones; Epirubicin; Female; Humans; Morpholines; NF-kappa B; Paclitaxel; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrrolidines; Signal Transduction; Thiocarbamates; Tissue Inhibitor of Metalloproteinase-1

2011
Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells.
    Breast cancer research : BCR, 2005, Volume: 7, Issue:6

    Topics: Anti-Infective Agents, Local; Antioxidants; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Clioquinol; Copper; Drug Interactions; Female; Humans; Precancerous Conditions; Proteasome Inhibitors; Pyrrolidines; Thiocarbamates

2005
NF-kappaB pathway inhibitors preferentially inhibit breast cancer stem-like cells.
    Breast cancer research and treatment, 2008, Volume: 111, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Ditiocarb; Female; Humans; Mice; Mice, Nude; Neoplastic Stem Cells; NF-kappa B; Paclitaxel; Pyrrolidines; Sesquiterpenes; Spheroids, Cellular; Thiocarbamates; Time Factors; Xenograft Model Antitumor Assays

2008
Copper uptake is required for pyrrolidine dithiocarbamate-mediated oxidation and protein level increase of p53 in cells.
    The Biochemical journal, 2002, Aug-01, Volume: 365, Issue:Pt 3

    Topics: Animals; Antioxidants; Breast Neoplasms; Cells, Cultured; Chelating Agents; Copper; Cysteine; Cysteine Proteinase Inhibitors; Ditiocarb; Female; Fibroblasts; Free Radicals; Humans; Hydrogen Peroxide; Leupeptins; Mannitol; Molecular Structure; Oxidants; Oxidation-Reduction; Pyrrolidines; Rats; Recombinant Proteins; Thiobarbituric Acid Reactive Substances; Thiocarbamates; Tumor Suppressor Protein p53

2002