pyrrolidine has been researched along with Alzheimer Disease in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (75.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aanouz, I; Ajana, MA; Bouachrine, M; El Khatabi, K; El-Mernissi, R; Khan, A; Lakhlifi, T; Wei, DQ | 1 |
| Al-Ghorbani, M; Farooq, U; Jan, MS; Javed, MA; Mannan, A; Rashid, U; Rauf, A; Sadiq, A; Shbeer, AM; Wilairatana, P | 1 |
| Choubey, PK; Seth, A; Shrivastava, SK; Tripathi, A; Tripathi, MK | 1 |
| Clader, JW; Gu, H; Guo, T; Hobbs, DW; Jacob, B; Rokosz, LL; Stauffer, TM | 1 |
4 other study(ies) available for pyrrolidine and Alzheimer Disease
| Article | Year |
|---|---|
Identification of novel acetylcholinesterase inhibitors through 3D-QSAR, molecular docking, and molecular dynamics simulation targeting Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Ligands; Molecular Docking Simulation; Molecular Dynamics Simulation; Pyrrolidines; Quantitative Structure-Activity Relationship; Random Allocation | 2021 |
Evaluation of pyrimidine/pyrrolidine-sertraline based hybrids as multitarget anti-Alzheimer agents: In-vitro, in-vivo, and computational studies.
Topics: Acetylcholinesterase; Alzheimer Disease; Cholinesterase Inhibitors; Humans; Molecular Docking Simulation; Pyrimidines; Sertraline; Structure-Activity Relationship | 2023 |
Design, synthesis, and evaluation of N-benzylpyrrolidine and 1,3,4-oxadiazole as multitargeted hybrids for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Female; Humans; Male; Maze Learning; Molecular Structure; Neuroprotective Agents; Oxadiazoles; Peptide Fragments; Pyrrolidines; Rats; Rats, Wistar; Structure-Activity Relationship | 2021 |
Design, synthesis, and evaluation of tetrahydroquinoline and pyrrolidine sulfonamide carbamates as gamma-secretase inhibitors.
Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Carbamates; Drug Design; Enzyme Inhibitors; Humans; Pyrrolidines; Quinolines; Structure-Activity Relationship; Sulfonamides | 2007 |