pyrrolidine-2,4-dicarboxylic acid has been researched along with Pregnancy in 4 studies
pyrrolidine-2,4-dicarboxylic acid: a glutamate uptake inhibitor
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " At a concentration that was not toxic by itself, L-trans-pyrrolidine-2,4-dicarboxylate increased the toxicity of glutamate approximately fivefold and slowed the clearance of glutamate from the extracellular space." | 1.29 | Inhibition of glutamate uptake with L-trans-pyrrolidine-2,4-dicarboxylate potentiates glutamate toxicity in primary hippocampal cultures. ( Buchhalter, JR; Djali, S; Robinson, MB, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pepponi, R | 1 |
| Ferrante, A | 1 |
| Ferretti, R | 1 |
| Martire, A | 1 |
| Popoli, P | 1 |
| Massieu, L | 1 |
| Haces, ML | 1 |
| Montiel, T | 1 |
| Hernández-Fonseca, K | 1 |
| Nafia, I | 1 |
| Re, DB | 1 |
| Masmejean, F | 1 |
| Melon, C | 1 |
| Kachidian, P | 1 |
| Kerkerian-Le Goff, L | 1 |
| Nieoullon, A | 1 |
| Had-Aissouni, L | 1 |
| Robinson, MB | 1 |
| Djali, S | 1 |
| Buchhalter, JR | 1 |
4 other studies available for pyrrolidine-2,4-dicarboxylic acid and Pregnancy
| Article | Year |
|---|---|
Region-specific neuroprotective effect of ZM 241385 towards glutamate uptake inhibition in cultured neurons.
Topics: Adenosine A2 Receptor Antagonists; Animals; Binding, Competitive; Biological Transport; Biomimetics; | 2009 |
Acetoacetate protects hippocampal neurons against glutamate-mediated neuronal damage during glycolysis inhibition.
Topics: Acetoacetates; Adenosine Triphosphate; Animals; Cell Survival; Cells, Cultured; Dicarboxylic Acids; | 2003 |
Preferential vulnerability of mesencephalic dopamine neurons to glutamate transporter dysfunction.
Topics: alpha-Synuclein; Analysis of Variance; Animals; Aspartic Acid; Cells, Cultured; Dicarboxylic Acids; | 2008 |
Inhibition of glutamate uptake with L-trans-pyrrolidine-2,4-dicarboxylate potentiates glutamate toxicity in primary hippocampal cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Cells, Cult | 1993 |