pyrrolidine-2,4-dicarboxylic acid has been researched along with Motor Neuron Disease in 1 studies
pyrrolidine-2,4-dicarboxylic acid: a glutamate uptake inhibitor
Motor Neuron Disease: Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andreassen, OA | 1 |
| Jenkins, BG | 1 |
| Dedeoglu, A | 1 |
| Ferrante, KL | 1 |
| Bogdanov, MB | 1 |
| Kaddurah-Daouk, R | 1 |
| Beal, MF | 1 |
1 other study available for pyrrolidine-2,4-dicarboxylic acid and Motor Neuron Disease
| Article | Year |
|---|---|
Increases in cortical glutamate concentrations in transgenic amyotrophic lateral sclerosis mice are attenuated by creatine supplementation.
Topics: Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Biological Transport; | 2001 |