pyrrolidine-2,4-dicarboxylic acid has been researched along with Mood Disorders in 1 studies
pyrrolidine-2,4-dicarboxylic acid: a glutamate uptake inhibitor
Mood Disorders: Those disorders that have a disturbance in mood as their predominant feature.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We demonstrate that chronic blockade of glutamate uptake by a glial/neuronal transporter antagonist L-trans-pyrrolidine-2,4-dicarboxylic acid (PDC) within the amygdala, a key area implicated in mood regulation, results in dose-dependent reduction in social exploratory behavior and disrupts circadian activity patterns consistent with symptoms of mood disorders." | 3.74 | Glia mechanisms in mood regulation: a novel model of mood disorders. ( Anand, A; Gaskins, D; Lee, Y; Shekhar, A, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, Y | 1 |
| Gaskins, D | 1 |
| Anand, A | 1 |
| Shekhar, A | 1 |
1 other study available for pyrrolidine-2,4-dicarboxylic acid and Mood Disorders
| Article | Year |
|---|---|
Glia mechanisms in mood regulation: a novel model of mood disorders.
Topics: Affect; Amino Acid Transport System X-AG; Amygdala; Animals; Astrocytes; Behavior, Animal; Circadian | 2007 |