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pyrrolidine-2,4-dicarboxylic acid and Brain Ischemia

pyrrolidine-2,4-dicarboxylic acid has been researched along with Brain Ischemia in 5 studies

pyrrolidine-2,4-dicarboxylic acid: a glutamate uptake inhibitor

Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"The effect of diethylmaleate administration on ascorbic acid release following cerebral ischemia was investigated in anesthetized rat brain cortex."7.70Diethylmaleate decreased ascorbic acid release induced by cerebral ischemia in cerebral cortex of the anesthetized rat. ( Kuo, JS; Lin, NN; Tsai, PJ; Yang, CS, 2000)
"The effect of diethylmaleate administration on ascorbic acid release following cerebral ischemia was investigated in anesthetized rat brain cortex."3.70Diethylmaleate decreased ascorbic acid release induced by cerebral ischemia in cerebral cortex of the anesthetized rat. ( Kuo, JS; Lin, NN; Tsai, PJ; Yang, CS, 2000)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's4 (80.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yang, CS2
Tsai, PJ2
Chen, WY1
Kuo, JS2
Obrenovitch, TP1
Zilkha, E1
Urenjak, J1
Jabaudon, D1
Scanziani, M1
Gähwiler, BH1
Gerber, U1
Lin, NN1
Massieu, L1
Del Río, P1
Montiel, T1

Other Studies

5 other studies available for pyrrolidine-2,4-dicarboxylic acid and Brain Ischemia

ArticleYear
Ionotropic glutamate receptors are involved in malondialdehyde production in anesthetized rat brain cortex: a microdialysis study.
    Redox report : communications in free radical research, 2003, Volume: 8, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Animals; Brain; Brain Ischemia

2003
Effects of pharmacological inhibition of glutamate-uptake on ischaemia-induced glutamate efflux and anoxic depolarization latency.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:3

    Topics: Brain; Brain Ischemia; Dicarboxylic Acids; Glutamic Acid; Hypoxia; Microdialysis; Neurotransmitter U

1998
Acute decrease in net glutamate uptake during energy deprivation.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, May-09, Volume: 97, Issue:10

    Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding C

2000
Diethylmaleate decreased ascorbic acid release induced by cerebral ischemia in cerebral cortex of the anesthetized rat.
    The Chinese journal of physiology, 2000, Jun-30, Volume: 43, Issue:2

    Topics: Amino Acid Transport System X-AG; Anesthesia; Animals; Ascorbic Acid; Brain Chemistry; Brain Ischemi

2000
Neurotoxicity of glutamate uptake inhibition in vivo: correlation with succinate dehydrogenase activity and prevention by energy substrates.
    Neuroscience, 2001, Volume: 106, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Amino Acid Transport System X-AG; Animals; Brain Ischemia; Con

2001