pyrrolidine-2,4-dicarboxylic acid has been researched along with Brain Ischemia in 5 studies
pyrrolidine-2,4-dicarboxylic acid: a glutamate uptake inhibitor
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of diethylmaleate administration on ascorbic acid release following cerebral ischemia was investigated in anesthetized rat brain cortex." | 7.70 | Diethylmaleate decreased ascorbic acid release induced by cerebral ischemia in cerebral cortex of the anesthetized rat. ( Kuo, JS; Lin, NN; Tsai, PJ; Yang, CS, 2000) |
| "The effect of diethylmaleate administration on ascorbic acid release following cerebral ischemia was investigated in anesthetized rat brain cortex." | 3.70 | Diethylmaleate decreased ascorbic acid release induced by cerebral ischemia in cerebral cortex of the anesthetized rat. ( Kuo, JS; Lin, NN; Tsai, PJ; Yang, CS, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, CS | 2 |
| Tsai, PJ | 2 |
| Chen, WY | 1 |
| Kuo, JS | 2 |
| Obrenovitch, TP | 1 |
| Zilkha, E | 1 |
| Urenjak, J | 1 |
| Jabaudon, D | 1 |
| Scanziani, M | 1 |
| Gähwiler, BH | 1 |
| Gerber, U | 1 |
| Lin, NN | 1 |
| Massieu, L | 1 |
| Del Río, P | 1 |
| Montiel, T | 1 |
5 other studies available for pyrrolidine-2,4-dicarboxylic acid and Brain Ischemia
| Article | Year |
|---|---|
Ionotropic glutamate receptors are involved in malondialdehyde production in anesthetized rat brain cortex: a microdialysis study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Animals; Brain; Brain Ischemia | 2003 |
Effects of pharmacological inhibition of glutamate-uptake on ischaemia-induced glutamate efflux and anoxic depolarization latency.
Topics: Brain; Brain Ischemia; Dicarboxylic Acids; Glutamic Acid; Hypoxia; Microdialysis; Neurotransmitter U | 1998 |
Acute decrease in net glutamate uptake during energy deprivation.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding C | 2000 |
Diethylmaleate decreased ascorbic acid release induced by cerebral ischemia in cerebral cortex of the anesthetized rat.
Topics: Amino Acid Transport System X-AG; Anesthesia; Animals; Ascorbic Acid; Brain Chemistry; Brain Ischemi | 2000 |
Neurotoxicity of glutamate uptake inhibition in vivo: correlation with succinate dehydrogenase activity and prevention by energy substrates.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Amino Acid Transport System X-AG; Animals; Brain Ischemia; Con | 2001 |