pyrrolidine-2,4-dicarboxylic acid has been researched along with Aging in 7 studies
pyrrolidine-2,4-dicarboxylic acid: a glutamate uptake inhibitor
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Using microdialysis, the effects of endogenous glutamate on extracellular concentrations of taurine, in striatum and nucleus accumbens of the awake rat during the normal process of aging were investigated." | 7.71 | Endogenous glutamate-taurine interaction in striatum and nucleus accumbens of the freely moving rat: studies during the normal process of aging. ( Del Arco, A; Mora, F; Prieto, L; Segovia, G, 2001) |
| "This study investigated the effects of aging on the actions of a specific glutamate reuptake blocker, L-trans-pyrrolidine-2, 4-dicarboxylic acid (PDC), in extracellular glutamate and glutamine in striatum of the awake rat." | 7.71 | Glutamate-glutamine cycle and aging in striatum of the awake rat: effects of a glutamate transporter blocker. ( Del Arco, A; Mora, F; Prieto, L; Segovia, G, 2001) |
| "Using microdialysis, the effects of endogenous glutamate on extracellular concentrations of taurine, in striatum and nucleus accumbens of the awake rat during the normal process of aging were investigated." | 3.71 | Endogenous glutamate-taurine interaction in striatum and nucleus accumbens of the freely moving rat: studies during the normal process of aging. ( Del Arco, A; Mora, F; Prieto, L; Segovia, G, 2001) |
| "This study investigated the effects of aging on the actions of a specific glutamate reuptake blocker, L-trans-pyrrolidine-2, 4-dicarboxylic acid (PDC), in extracellular glutamate and glutamine in striatum of the awake rat." | 3.71 | Glutamate-glutamine cycle and aging in striatum of the awake rat: effects of a glutamate transporter blocker. ( Del Arco, A; Mora, F; Prieto, L; Segovia, G, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nyitrai, G | 1 |
| Lasztóczi, B | 1 |
| Kardos, J | 1 |
| Massieu, L | 1 |
| Tapia, R | 1 |
| Katsumori, H | 1 |
| Baldwin, RA | 1 |
| Wasterlain, CG | 1 |
| Overstreet, LS | 1 |
| Kinney, GA | 1 |
| Liu, YB | 1 |
| Billups, D | 1 |
| Slater, NT | 1 |
| Del Arco, A | 2 |
| Segovia, G | 2 |
| Prieto, L | 2 |
| Mora, F | 2 |
| Wall, MJ | 1 |
| Robert, A | 1 |
| Howe, JR | 1 |
| Usowicz, MM | 1 |
7 other studies available for pyrrolidine-2,4-dicarboxylic acid and Aging
| Article | Year |
|---|---|
Glutamate uptake shapes low-[Mg2+] induced epileptiform activity in juvenile rat hippocampal slices.
Topics: Aging; Animals; Aspartic Acid; CA3 Region, Hippocampal; Dicarboxylic Acids; Dose-Response Relationsh | 2010 |
Glutamate uptake impairment and neuronal damage in young and aged rats in vivo.
Topics: Aging; Amino Acids; Animals; Aspartic Acid; Corpus Striatum; Dicarboxylic Acids; Glutamic Acid; Hipp | 1997 |
Reverse transport of glutamate during depolarization in immature hippocampal slices.
Topics: Aging; Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Biological Tran | 1999 |
Glutamate transporters contribute to the time course of synaptic transmission in cerebellar granule cells.
Topics: Aging; Animals; Aspartic Acid; Benzothiadiazines; Cerebellum; Dicarboxylic Acids; Electric Stimulati | 1999 |
Endogenous glutamate-taurine interaction in striatum and nucleus accumbens of the freely moving rat: studies during the normal process of aging.
Topics: Aging; Animals; Corpus Striatum; Dicarboxylic Acids; Glutamic Acid; Locomotion; Male; Microdialysis; | 2001 |
Glutamate-glutamine cycle and aging in striatum of the awake rat: effects of a glutamate transporter blocker.
Topics: Aging; Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Corpus Striatum | 2001 |
The speeding of EPSC kinetics during maturation of a central synapse.
Topics: Aging; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Antihypertensive Agents; Benzoth | 2002 |