pyrrolidine-2,4-dicarboxylic acid has been researched along with ALS - Amyotrophic Lateral Sclerosis in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tapia, R; Tovar-y-Romo, LB | 1 |
| Bendotti, C; Rattray, M | 1 |
| Akaike, A; Ibi, M; Inoue, R; Kihara, T; Kimura, J; Kitamura, Y; Sawada, H; Shimohama, S; Taniguchi, T; Urushitani, M | 1 |
3 other study(ies) available for pyrrolidine-2,4-dicarboxylic acid and ALS - Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Cerebral neurons of transgenic ALS mice are vulnerable to glutamate release stimulation but not to increased extracellular glutamate due to transport blockade.
Topics: 4-Aminopyridine; Amyotrophic Lateral Sclerosis; Animals; Biological Transport; Dicarboxylic Acids; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; HSP72 Heat-Shock Proteins; Humans; Mice; Mice, Transgenic; Microdialysis; Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Superoxide Dismutase | 2006 |
Does excitotoxic cell death of motor neurons in ALS arise from glutamate transporter and glutamate receptor abnormalities?
Topics: Amyotrophic Lateral Sclerosis; Animals; Biological Transport; Cell Death; Dicarboxylic Acids; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamate Plasma Membrane Transport Proteins; Glutamates; Humans; Mice; Motor Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Receptors, Glutamate | 2006 |
Mechanism of selective motor neuronal death after exposure of spinal cord to glutamate: involvement of glutamate-induced nitric oxide in motor neuron toxicity and nonmotor neuron protection.
Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Death; Cell Survival; Cells, Cultured; Cyclic GMP; Dicarboxylic Acids; Embryo, Mammalian; Glutamic Acid; Models, Neurological; Motor Neurons; N-Methylaspartate; Neurons; Neurotransmitter Uptake Inhibitors; Nitric Oxide; Nitric Oxide Donors; Pyrrolidines; Rats; Rats, Wistar; Spinal Cord | 1998 |