Page last updated: 2024-08-18

pyrroles and Pulmonary Arterial Hypertension

pyrroles has been researched along with Pulmonary Arterial Hypertension in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (33.33)24.3611
2020's16 (66.67)2.80

Authors

AuthorsStudies
Arsalane, S; Guan, T; Jiang, SY; Jiang, X; Kim, D; Nicolls, MR; Pasupneti, S; Tamosiuniene, R; Tang, Q; Tian, W; Voelkel, NF1
Chapman, RW; Chun, D; Cipolla, D; Corboz, MR; Gauani, H; Li, Z; Malinin, V; Perkins, WR; Plaunt, AJ1
Bigby, TD; Breen, EC; Cannon, DT; Gilmore, NK; Gutierrez-Gonzalez, AK; Nogueira, L1
Hidaka, H; Maruyama, J; Maruyama, K; Naito, A; Sakao, S; Sanada, TJ; Shoji, H; Sumi, K; Tatsumi, K; Yoshida, Y; Zhang, E1
Anderson, SA; Chen, LY; Danner, RL; Dougherty, EJ; Elinoff, JM; Gairhe, S; Johnston, KA; Lu, M; Mazer, AJ; Nelson, JNH; Noguchi, A; Siddique, MAH; Solomon, MA; Solomon, SB; Sun, J; Vanderpool, RR; Wang, H; Wang, S; Yu, ZX; Zou, Y1
Ghofrani, HA; Grimminger, F; Hadzic, S; Kojonazarov, B; Schermuly, RT; Seeger, W; Weissmann, N1
Bogaard, HJ; Chaudhary, KR; Hansmann, G; Legchenko, E; Stewart, DJ; Sun, XQ1
Acoba, MG; Bigham, Z; Claypool, SM; Damarla, M; Huetsch, JC; Jiang, H; Kirsch, BJ; Kliment, C; Le, A; Servinsky, L; Shimoda, LA; Suresh, K; Zaldumbide, J1
Ding, Y; Huang, W; Kong, H; Liu, P; Peng, L; Tan, Q; Wang, H; Wang, J; Wang, Y; Xie, W; Yang, M; Yu, M; Zhou, H1
Fuchikami, C; Honda, Y; Kosugi, K; Kuramoto, K; Kuwano, K; Numakura, Y1
Adão, R; Bialesova, L; Brás-Silva, C; Kinsella, BT; Mendes-Ferreira, P; Mulvaney, EP; Reid, HM1
Andersen, A; Andersen, S; Axelsen, JB; Bogaard, HJ; da Silva Goncalves Bos, D; de Man, FS; Gomez-Puerto, MC; Goumans, MJ; Kurakula, K; Pan, X; Peters, EL; Schalij, I; Schiepers, REJ; Sun, XQ; Szulcek, R; van der Laarse, WJ; Vonk Noordegraaf, A1
Kikuchi, N; Kurosawa, R; Miyata, S; Nakata, T; Nogi, M; Omura, J; Satoh, K; Satoh, T; Shimokawa, H; Shindo, T; Siddique, MAH; Sunamura, S; Takeuchi, Y1
Higuchi, T; Inagaki, T; Masaki, T; Nakaoka, Y; Pearson, JT; Saito, S; Schwenke, DO; Shirai, M; Tsuchimochi, H; Umetani, K1
Kawakami, E; Miwa, H; Naito, A; Sakao, S; Sanada, TJ; Shoji, H; Suda, R; Tanabe, N; Tatsumi, K1
Banerjee, S; Clark, VR; Fishbein, G; Hong, J; Park, JF; Razee, A; Saddic, L; Umar, S; Williams, T1
Hata, A; Kato, F; Kobayashi, T; Miwa, H; Nishimura, R; Sakao, S; Sanada, TJ; Shiina, Y; Suzuki, H; Tanabe, N; Tatsumi, K; Voelkel, N; Yoshino, I1
Ben-Batalla, I; Caruso, P; Gall, H; Ghofrani, HA; Götz, E; Grimminger, F; Herpel, S; Kojonazarov, B; Lepper, C; Loges, S; Manaud, G; Morrell, NW; Novoyatleva, T; Perros, F; Presser, N; Rai, N; Schermuly, RT; Seeger, W; Shihan, M; Upton, PD; Veeroju, S; Weissmann, N; Wharton, J; Wilkins, M1
Bogaard, HJ; da Silva Gonçalves Bos, D; de Man, FS; de Raaf, MA; Dickhoff, C; Goumans, MJ; Guignabert, C; Happé, C; Herrmann, FE; Koolwijk, P; Kuiper, VP; Kurakula, K; Lodder, K; Pan, X; Rol, N; Schalij, I; Sun, XQ; Szulcek, R; Thuillet, R; Tu, L; van Nieuw Amerongen, GP; Vonk-Noordegraaf, A; Wollin, L1
Adorini, K; Brown, M; Habib, P; Joshua, F; McLean, A; Ng, B; Podgorski, M; Tjeuw, M1
Chesler, NC; Hacker, TA; Schmuck, EG; Schreier, DA; Wang, Z1
Carman, BL; Machado, R; Predescu, DN; Predescu, SA1
Bonini, MG; Castellon, M; Chen, J; Comhair, S; Erzurum, S; Machado, RF; Mao, M; Minshall, RD; Oliveira, SDS; Raj, JU; Silva, CLM1
Al-Mamun, ME; Aoki, J; Doi, T; Kano, K; Kikuchi, H; Kikuchi, N; Kurosawa, R; Matsumoto, Y; Miyata, S; Nogi, M; Numano, K; Omura, J; Oshima, Y; Saigusa, D; Satoh, K; Satoh, T; Shimokawa, H; Siddique, MAH; Sunamura, S; Uruno, A; Yamamoto, M1

Reviews

2 review(s) available for pyrroles and Pulmonary Arterial Hypertension

ArticleYear
The Role of Regulatory T Cells in Pulmonary Arterial Hypertension.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Animals; Autoimmunity; Endothelium, Vascular; Humans; Indoles; Pulmonary Arterial Hypertension; Pyrroles; Rats; Sex Characteristics; T-Lymphocytes, Regulatory; Vascular System Injuries

2021
Plexiform Arteriopathy in Rodent Models of Pulmonary Arterial Hypertension.
    The American journal of pathology, 2019, Volume: 189, Issue:6

    Topics: Animals; Disease Models, Animal; Disease Progression; Humans; Hypoxia; Indoles; MAP Kinase Signaling System; Mice; Mice, Knockout; Pulmonary Arterial Hypertension; Pulmonary Artery; Pyrroles; Rats

2019

Other Studies

22 other study(ies) available for pyrroles and Pulmonary Arterial Hypertension

ArticleYear
Treprostinil palmitil inhibits the hemodynamic and histopathological changes in the pulmonary vasculature and heart in an animal model of pulmonary arterial hypertension.
    European journal of pharmacology, 2022, Feb-05, Volume: 916

    Topics: Administration, Inhalation; Administration, Oral; Animals; Collagen; Disease Models, Animal; Epoprostenol; Heart; Hemodynamics; Hypoxia; Indoles; Male; Myocardium; Phosphodiesterase 5 Inhibitors; Pulmonary Arterial Hypertension; Pulmonary Artery; Pyrroles; Rats, Sprague-Dawley; Sildenafil Citrate; Vascular Remodeling; Vasodilator Agents

2022
Role of IL-33 receptor (ST2) deletion in diaphragm contractile and mitochondrial function in the Sugen5416/hypoxia model of pulmonary hypertension.
    Respiratory physiology & neurobiology, 2022, Volume: 295

    Topics: Animals; Diaphragm; Disease Models, Animal; Hypertension, Pulmonary; Hypoxia; Indoles; Interleukin-1 Receptor-Like 1 Protein; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Mitochondrial Diseases; Muscle Contraction; Protein Kinase Inhibitors; Pulmonary Arterial Hypertension; Pyrroles

2022
The Isoquinoline-Sulfonamide Compound H-1337 Attenuates SU5416/Hypoxia-Induced Pulmonary Arterial Hypertension in Rats.
    Cells, 2021, 12-27, Volume: 11, Issue:1

    Topics: Animals; Cell Proliferation; Heart Ventricles; Humans; Hypoxia; Indoles; Isoquinolines; Lung; Male; Metabolome; Myosin Light Chains; Phosphorylation; Proto-Oncogene Proteins c-akt; Pulmonary Arterial Hypertension; Pyrroles; Rats, Sprague-Dawley; Sulfonamides; TOR Serine-Threonine Kinases; Vascular Remodeling

2021
Mineralocorticoid receptor antagonist treatment of established pulmonary arterial hypertension improves interventricular dependence in the SU5416-hypoxia rat model.
    American journal of physiology. Lung cellular and molecular physiology, 2022, 03-01, Volume: 322, Issue:3

    Topics: Animals; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Humans; Hypertension, Pulmonary; Hypoxia; Indoles; Mineralocorticoid Receptor Antagonists; Pulmonary Arterial Hypertension; Pyrroles; Rats; Ventricular Dysfunction, Right

2022
Reply to Bogaard
    American journal of respiratory and critical care medicine, 2019, 12-01, Volume: 200, Issue:11

    Topics: Animals; Emphysema; Hypertension, Pulmonary; Hypoxia; Indoles; Phenotype; Pulmonary Arterial Hypertension; Pyrroles; Rats

2019
Emphysema Is-at the Most-Only a Mild Phenotype in the Sugen/Hypoxia Rat Model of Pulmonary Arterial Hypertension.
    American journal of respiratory and critical care medicine, 2019, 12-01, Volume: 200, Issue:11

    Topics: Animals; Emphysema; Hypertension, Pulmonary; Hypoxia; Indoles; Phenotype; Pulmonary Arterial Hypertension; Pyrroles; Rats

2019
Regulation of mitochondrial fragmentation in microvascular endothelial cells isolated from the SU5416/hypoxia model of pulmonary arterial hypertension.
    American journal of physiology. Lung cellular and molecular physiology, 2019, 11-01, Volume: 317, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Calcium; Cells, Cultured; Endothelial Cells; Hypoxia; Indoles; Lung; Male; Mitochondria; Oxygen Consumption; Pulmonary Arterial Hypertension; Pyrroles; Rats; Rats, Wistar; Reactive Oxygen Species; Vascular Remodeling

2019
Paeoniflorin Ameliorates Chronic Hypoxia/SU5416-Induced Pulmonary Arterial Hypertension by Inhibiting Endothelial-to-Mesenchymal Transition.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Animals; Cells, Cultured; Chronic Disease; Disease Models, Animal; Endothelial Cells; Epithelial-Mesenchymal Transition; Glucosides; Humans; Hypoxia; Indoles; Injections, Subcutaneous; Male; Monoterpenes; Oxygen; Pulmonary Arterial Hypertension; Pyrroles; Rats; Rats, Sprague-Dawley

2020
The selective PGI2 receptor agonist selexipag ameliorates Sugen 5416/hypoxia-induced pulmonary arterial hypertension in rats.
    PloS one, 2020, Volume: 15, Issue:10

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetamides; Animals; Cell Proliferation; Collagen Type I; Disease Models, Animal; Heart Ventricles; Hemodynamics; Hypertrophy, Right Ventricular; Hypoxia; Indoles; Lung; Male; Pulmonary Arterial Hypertension; Pyrazines; Pyrroles; Rats, Sprague-Dawley; Receptors, Epoprostenol; Systole; Vascular Remodeling

2020
Efficacy of the thromboxane receptor antagonist NTP42 alone, or in combination with sildenafil, in the sugen/hypoxia-induced model of pulmonary arterial hypertension.
    European journal of pharmacology, 2020, Dec-15, Volume: 889

    Topics: Angiogenesis Inhibitors; Animals; Drug Therapy, Combination; Hypoxia; Indoles; Male; Pulmonary Arterial Hypertension; Pyrroles; Rats; Rats, Wistar; Receptors, Thromboxane A2, Prostaglandin H2; Sildenafil Citrate; Treatment Outcome; Vasodilator Agents

2020
Increased MAO-A Activity Promotes Progression of Pulmonary Arterial Hypertension.
    American journal of respiratory cell and molecular biology, 2021, Volume: 64, Issue:3

    Topics: Animals; Clorgyline; Disease Models, Animal; Disease Progression; Heart Ventricles; Humans; Hypertrophy, Right Ventricular; Indoles; Monoamine Oxidase; Oxidative Stress; Pulmonary Arterial Hypertension; Pulmonary Artery; Pyrroles; Rats; Vascular Remodeling; Vascular Stiffness; Vasodilation

2021
Identification of Celastrol as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension and Right Ventricular Failure Through Suppression of Bsg (Basigin)/CyPA (Cyclophilin A).
    Arteriosclerosis, thrombosis, and vascular biology, 2021, Volume: 41, Issue:3

    Topics: Animals; Antihypertensive Agents; Basigin; Cyclophilin A; Disease Models, Animal; Humans; Hypoxia; Indoles; Mice; Mice, Transgenic; Myocytes, Cardiac; Pentacyclic Triterpenes; Pulmonary Arterial Hypertension; Pyrroles; Rats; Triterpenes; Ventricular Dysfunction, Right

2021
Evaluation of right coronary vascular dysfunction in severe pulmonary hypertensive rats using synchrotron radiation microangiography.
    American journal of physiology. Heart and circulatory physiology, 2021, 03-01, Volume: 320, Issue:3

    Topics: Animals; Antihypertensive Agents; Coronary Angiography; Coronary Vessels; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Hypertrophy, Right Ventricular; Hypoxia; Indoles; Monocrotaline; Predictive Value of Tests; Pulmonary Arterial Hypertension; Pyrimidines; Pyrroles; Rats, Sprague-Dawley; Severity of Illness Index; Sulfonamides; Synchrotrons; Vasodilation; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Remodeling

2021
Metabolic remodeling in the right ventricle of rats with severe pulmonary arterial hypertension.
    Molecular medicine reports, 2021, Volume: 23, Issue:4

    Topics: Animals; Citric Acid Cycle; Fatty Acids; Glucose; Heart Ventricles; Humans; Hypertrophy, Right Ventricular; Hypoxia; Indoles; Oxidation-Reduction; Pulmonary Arterial Hypertension; Pyrroles; Rats; Rats, Sprague-Dawley; Ventricular Remodeling

2021
Transcriptomic Analysis of Right Ventricular Remodeling in Two Rat Models of Pulmonary Hypertension: Identification and Validation of Epithelial-to-Mesenchymal Transition in Human Right Ventricular Failure.
    Circulation. Heart failure, 2021, Volume: 14, Issue:2

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Animals; Disease Models, Animal; Epithelial-Mesenchymal Transition; Female; Gene Expression Profiling; Heart Failure; Heart Ventricles; Humans; Hypoxia; Indoles; Male; Middle Aged; Monocrotaline; Pulmonary Arterial Hypertension; Pyrroles; Rats; Real-Time Polymerase Chain Reaction; RNA-Seq; Transcriptome; Ventricular Dysfunction, Right; Ventricular Remodeling

2021
Cell Tracking Suggests Pathophysiological and Therapeutic Role of Bone Marrow Cells in Sugen5416/Hypoxia Rat Model of Pulmonary Arterial Hypertension.
    The Canadian journal of cardiology, 2021, Volume: 37, Issue:6

    Topics: Angiogenesis Inhibitors; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Cell Tracking; Disease Models, Animal; Female; Hypoxia; Indoles; Lung; Male; Neointima; Pulmonary Arterial Hypertension; Pulmonary Artery; Pyrroles; Rats; Transplantation Chimera; Vascular Remodeling

2021
Deficiency of Axl aggravates pulmonary arterial hypertension via BMPR2.
    Communications biology, 2021, 08-24, Volume: 4, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Bone Morphogenetic Protein Receptors, Type II; Gene Expression Regulation; Indoles; Male; Monocrotaline; Pulmonary Arterial Hypertension; Pyrroles; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases

2021
Nintedanib improves cardiac fibrosis but leaves pulmonary vascular remodelling unaltered in experimental pulmonary hypertension.
    Cardiovascular research, 2019, 02-01, Volume: 115, Issue:2

    Topics: Adult; Animals; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Extracellular Matrix; Female; Fibroblasts; Fibrosis; Humans; Indoles; Male; Myocardium; Protein Kinase Inhibitors; Pulmonary Arterial Hypertension; Pulmonary Artery; Pyrroles; Rats, Sprague-Dawley; Vascular Remodeling; Ventricular Function, Right; Ventricular Remodeling; Young Adult

2019
First Reported Case of Pulmonary Arterial Hypertension Secondary to Tofacitinib Treatment for Undifferentiated Arthritis.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2021, Jun-01, Volume: 27, Issue:4

    Topics: Antirheumatic Agents; Arthritis; Humans; Piperidines; Pulmonary Arterial Hypertension; Pyrimidines; Pyrroles; Treatment Outcome

2021
Beneficial effects of mesenchymal stem cell delivery via a novel cardiac bioscaffold on right ventricles of pulmonary arterial hypertensive rats.
    American journal of physiology. Heart and circulatory physiology, 2019, 05-01, Volume: 316, Issue:5

    Topics: Animals; Arterial Pressure; Cells, Cultured; Disease Models, Animal; Fibrosis; Hypertrophy, Right Ventricular; Hypoxia; Indoles; Male; Mesenchymal Stem Cell Transplantation; Myocardial Contraction; Myocardium; Pulmonary Arterial Hypertension; Pulmonary Artery; Pyrroles; Rats, Sprague-Dawley; Recovery of Function; Regeneration; Tissue Scaffolds; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Remodeling; von Willebrand Factor

2019
Injury-Induced Shedding of Extracellular Vesicles Depletes Endothelial Cells of Cav-1 (Caveolin-1) and Enables TGF-β (Transforming Growth Factor-β)-Dependent Pulmonary Arterial Hypertension.
    Arteriosclerosis, thrombosis, and vascular biology, 2019, Volume: 39, Issue:6

    Topics: Adolescent; Adult; Aged; Animals; Bone Morphogenetic Protein Receptors, Type II; Case-Control Studies; Caveolin 1; Cell Proliferation; Disease Models, Animal; Endothelial Cells; Extracellular Vesicles; Female; Humans; Hypoxia; Indoles; Male; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Nitric Oxide Synthase Type III; Pulmonary Arterial Hypertension; Pyrroles; Rats, Sprague-Dawley; Signal Transduction; Smad Proteins; Transforming Growth Factor beta; Vascular Remodeling; Young Adult

2019
Identification of Celastramycin as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension.
    Circulation research, 2019, 07-19, Volume: 125, Issue:3

    Topics: Animals; Cells, Cultured; Cytokines; Disease Models, Animal; Drug Evaluation, Preclinical; Energy Metabolism; High-Throughput Screening Assays; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Indoles; Male; Metabolome; Mice; Mitochondria; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Naphthoquinones; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Pulmonary Arterial Hypertension; Pulmonary Artery; Pyrroles; Rats; Reactive Oxygen Species; Resorcinols; Transcription Factors

2019