pyrroles has been researched along with Peptic Ulcer in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (23.08) | 18.7374 |
| 1990's | 2 (7.69) | 18.2507 |
| 2000's | 4 (15.38) | 29.6817 |
| 2010's | 8 (30.77) | 24.3611 |
| 2020's | 6 (23.08) | 2.80 |
| Authors | Studies |
|---|---|
| DeVault, K; Hunt, B; Katz, P; Laine, L; Lowe, J; Mitev, S; Spechler, S | 1 |
| Aizawa, F; Ando-Matsuoka, R; Goda, M; Hamano, H; Ishizawa, K; Izawa-Ishizawa, Y; Maruo, A; Miyata, K; Niimura, T; Sakaguchi, S; Sakajiri, Y; Sawada, R; Shibata, T; Takaoka, M; Yagi, K; Yamanishi, Y; Zamami, Y | 1 |
| Facius, A; Howden, CW; Hunt, R; Lahu, G; Leifke, E; Mulford, DJ; Scarpignato, C | 1 |
| Cash, BD; Merchant, A; Ramani, A | 1 |
| Adler, DG; Bapaye, J; Chandan, OC; Chandan, S; Deliwala, S; Dhindsa, B; Facciorusso, A; Kassab, LL; Mohan, BP; Ramai, D | 1 |
| Bai, G; Gao, Y; He, J; Sun, Y; Wang, J | 1 |
| Ashida, K; Funao, N; Kawai, T; Mizokami, Y; Nishimura, A; Oda, K; Soen, S; Sugano, K | 1 |
| Ashida, K; Funao, N; Kawai, T; Matsumoto, Y; Mizokami, Y; Nishimura, A; Oda, K; Sugano, K | 1 |
| Chen, QT; He, HS; Li, BY; Shi, B; Shi, J; Song, CY | 1 |
| Echizen, H | 1 |
| Asaka, M; Funao, N; Murakami, K; Nishimura, A; Sakurai, Y; Shiino, M | 1 |
| Bernatsky, S; Curtis, JR; Xie, F; Yun, H | 1 |
| Fujita, M; Graham, DY; Haruma, K; Ishii, M; Kamada, T; Katsumata, R; Matsumoto, H; Murao, T; Nakato, R; Shiotani, A | 1 |
| Alam, MM; Anwer, T; Hasan, SM; Husain, A | 1 |
| Arikawa, Y; Hamada, T; Hasuoka, A; Hirase, K; Hori, Y; Imanishi, A; Inatomi, N; Kajino, M; Kondo, M; Kurasawa, O; Matsukawa, J; Nishida, H; Takagi, T; Takeuchi, T; Tarui, N | 1 |
| Hawkey, CJ; Skelly, MM | 1 |
| Bias, P; Buchner, A; Klesser, B; Laufer, S | 1 |
| Nakamura, H; Shimizu, M; Yokoyama, Y | 1 |
| Kadokawa, T; Motoyoshi, S; Nakamura, H; Seto, Y; Shimizu, M; Yokoyama, Y | 1 |
| Algate, DR; Atterson, PR; Augustin, J; Elsässer, R; Laufer, S; Munt, PL; Tries, S | 1 |
| Dobrilla, G | 1 |
| Boyle, E; Freeman, PC; Goudie, AC; Mangan, FR; Thomson, M | 1 |
| Amico-Roxas, M; Attaguile, G; Caruso, A; Cutuli, VM; De Bernardis, E | 1 |
| Hunter, JR; Jick, H; Jick, SS; Walker, AM | 1 |
| Ballinger, WF; Wise, L | 1 |
| Harris, PN; Lin, TM | 1 |
6 review(s) available for pyrroles and Peptic Ulcer
| Article | Year |
|---|---|
Review of the clinical development of fexuprazan for gastroesophageal reflux-related disease.
Topics: Esophagitis; Gastroesophageal Reflux; Humans; Peptic Ulcer; Proton Pump Inhibitors; Pyrroles | 2023 |
Vonoprazan versus lansoprazole in erosive esophagitis - A systematic review and meta-analysis of randomized controlled trials.
Topics: Esophagitis; Humans; Lansoprazole; Peptic Ulcer; Proton Pump Inhibitors; Pyrroles; Randomized Controlled Trials as Topic | 2023 |
Network meta-analysis of multiple doses of vonoprazan for the treatment of erosive esophagitis.
Topics: Esophagitis, Peptic; Humans; Network Meta-Analysis; Peptic Ulcer; Proton Pump Inhibitors; Pyrroles; Treatment Outcome | 2023 |
Comparison of the Use of Vonoprazan and Proton Pump Inhibitors for the Treatment of Peptic Ulcers Resulting from Endoscopic Submucosal Dissection: A Systematic Review and Meta-Analysis.
Topics: Endoscopic Mucosal Resection; Humans; Peptic Ulcer; Postoperative Complications; Proton Pump Inhibitors; Pyrroles; Stomach Neoplasms; Sulfonamides; Treatment Outcome; Wound Healing | 2019 |
The First-in-Class Potassium-Competitive Acid Blocker, Vonoprazan Fumarate: Pharmacokinetic and Pharmacodynamic Considerations.
Topics: Administration, Oral; Animals; Biological Availability; Cytochrome P-450 CYP2C19; H(+)-K(+)-Exchanging ATPase; Humans; Peptic Ulcer; Proton Pump Inhibitors; Pyrroles; Randomized Controlled Trials as Topic; Sulfonamides | 2016 |
COX-LOX inhibition: current evidence for an emerging new therapy.
Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arthritis; Clinical Trials, Phase III as Topic; Cyclooxygenase Inhibitors; Dogs; Humans; Intestinal Mucosa; Leukotrienes; Lipoxygenase Inhibitors; Models, Animal; Peptic Ulcer; Prostaglandins; Pyrroles; Rats; Sheep | 2003 |
5 trial(s) available for pyrroles and Peptic Ulcer
| Article | Year |
|---|---|
Vonoprazan Versus Lansoprazole for Healing and Maintenance of Healing of Erosive Esophagitis: A Randomized Trial.
Topics: Adult; Esophagitis; Humans; Lansoprazole; Peptic Ulcer; Proton Pump Inhibitors; Pyrroles; Sulfonamides; Treatment Outcome | 2023 |
Vonoprazan prevents ulcer recurrence during long-term NSAID therapy: randomised, lansoprazole-controlled non-inferiority and single-blind extension study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Double-Blind Method; Equivalence Trials as Topic; Female; Gastrointestinal Hemorrhage; Humans; Lansoprazole; Male; Middle Aged; Peptic Ulcer; Pyrroles; Recurrence; Secondary Prevention; Single-Blind Method; Sulfonamides; Survival Analysis; Treatment Outcome | 2018 |
Vonoprazan prevents low-dose aspirin-associated ulcer recurrence: randomised phase 3 study.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Double-Blind Method; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Japan; Lansoprazole; Male; Middle Aged; Peptic Ulcer; Pyrroles; Recurrence; Secondary Prevention; Sulfonamides; Treatment Outcome | 2018 |
Vonoprazan, a novel potassium-competitive acid blocker, as a component of first-line and second-line triple therapy for Helicobacter pylori eradication: a phase III, randomised, double-blind study.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Double-Blind Method; Drug Administration Schedule; Drug Monitoring; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Male; Metronidazole; Middle Aged; Peptic Ulcer; Proton Pump Inhibitors; Pyrroles; Sulfonamides; Treatment Outcome | 2016 |
The gastrointestinal tolerability of the LOX/COX inhibitor, licofelone, is similar to placebo and superior to naproxen therapy in healthy volunteers: results from a randomized, controlled trial.
Topics: Acetates; Adult; Cyclooxygenase Inhibitors; Duodenoscopy; Duodenum; Female; Gastric Mucosa; Gastroscopy; Humans; Incidence; Intestinal Mucosa; Lipoxygenase Inhibitors; Male; Naproxen; Peptic Ulcer; Pyrroles | 2004 |
15 other study(ies) available for pyrroles and Peptic Ulcer
| Article | Year |
|---|---|
Differential effects of proton pump inhibitors and vonoprazan on vascular endothelial growth factor expression in cancer cells.
Topics: Endothelial Growth Factors; Humans; Molecular Docking Simulation; Neoplasms; Peptic Ulcer; Proton Pump Inhibitors; Pyrroles | 2023 |
A translational pharmacokinetic/pharmacodynamic approach supports optimal vonoprazan dosing for erosive oesophagitis and Helicobacter pylori infection.
Topics: Esophagitis; Female; Helicobacter Infections; Helicobacter pylori; Humans; Male; Peptic Ulcer; Proton Pump Inhibitors; Pyrroles | 2023 |
Brief Report: Risk of Gastrointestinal Perforation Among Rheumatoid Arthritis Patients Receiving Tofacitinib, Tocilizumab, or Other Biologic Treatments.
Topics: Abatacept; Adult; Age Factors; Aged; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Biological Products; Databases, Factual; Diverticulitis; Esophageal Perforation; Female; Gastroesophageal Reflux; Glucocorticoids; Humans; Incidence; Intestinal Perforation; Male; Medicare; Middle Aged; Peptic Ulcer; Piperidines; Prednisone; Proportional Hazards Models; Pyrimidines; Pyrroles; Risk Factors; Rituximab; Tumor Necrosis Factor-alpha; United States | 2016 |
Helicobacter pylori Eradication with Proton Pump Inhibitors or Potassium-Competitive Acid Blockers: The Effect of Clarithromycin Resistance.
Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Carbon Isotopes; Clarithromycin; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Peptic Ulcer; Polymerase Chain Reaction; Proton Pump Inhibitors; Pyrroles; Retrospective Studies; RNA, Ribosomal, 23S; Sulfonamides; Treatment Outcome; Urea | 2016 |
Synthesis and pharmacological evaluation of 2(3H)-furanones and 2(3H)-pyrrolones, combining analgesic and anti-inflammatory properties with reduced gastrointestinal toxicity and lipid peroxidation.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Edema; Female; Furans; Lipid Peroxidation; Male; Mice; Molecular Structure; Pain Measurement; Peptic Ulcer; Pyrroles; Rats; Rats, Wistar; Stereoisomerism; Structure-Activity Relationship | 2009 |
Discovery of a novel pyrrole derivative 1-[5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine fumarate (TAK-438) as a potassium-competitive acid blocker (P-CAB).
Topics: Animals; Anti-Ulcer Agents; Dogs; Enzyme Inhibitors; Fumarates; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Male; Molecular Structure; Peptic Ulcer; Proton Pump Inhibitors; Pyrroles; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Sulfonamides | 2012 |
Gastrointestinal ulcerogenic activity of tolmetin sodium in rats in comparison with those of indomethacin and aspirin.
Topics: Animals; Aspirin; Indomethacin; Male; Peptic Ulcer; Pyrroles; Rats; Rats, Inbred Strains; Tolmetin | 1984 |
[Anti-inflammatory activity of a non-steroidal anti-inflammatory agent, zomepirac sodium, in experimental animals].
Topics: Adrenalectomy; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Capillary Permeability; Depression, Chemical; Edema; Guinea Pigs; In Vitro Techniques; Male; Mice; Peptic Ulcer; Prostaglandins; Protein Denaturation; Pyrroles; Rabbits; Rats; Tolmetin | 1982 |
Gastrointestinal tolerance of [2,2-dimethyl-6-(4-chlorophenyl-7-phenyl- 2,3-dihydro-1H-pyrrolizine-5-yl]-acetic acid in the rat.
Topics: Acetates; Animals; Gastric Mucosa; Indomethacin; Intestinal Mucosa; Lipoxygenase Inhibitors; Male; Peptic Ulcer; Peptic Ulcer Hemorrhage; Pyrroles; Rats; Rats, Wistar | 1994 |
Nitric oxide and non steroidal antiinflammatory drugs (NSAID)-related gastroduodenal damage.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Gastric Mucosa; Glycine; Humans; Nitric Oxide; Peptic Ulcer; Pyrroles | 2001 |
The role of copper in preventing gastrointestinal damage by acidic anti-inflammatory drugs.
Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chelating Agents; Copper; Edema; Female; In Vitro Techniques; Indomethacin; Ketoprofen; Male; Naproxen; Niflumic Acid; Peptic Ulcer; Prostaglandins E; Pyrroles; Rats | 1976 |
Pharmacological properties and toxicology of MED-15, a prodrug of tolmetin.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Glycine; Lethal Dose 50; Male; Peptic Ulcer; Prodrugs; Pyrroles; Rats; Rats, Wistar; Tolmetin | 1992 |
Follow-up study of tolmetin users.
Topics: Adult; Aged; Aging; Female; Follow-Up Studies; Humans; Male; Middle Aged; Peptic Ulcer; Product Surveillance, Postmarketing; Pyrroles; Sex Factors; Tolmetin | 1989 |
Human gastric mucus: quantitative and qualitative studies.
Topics: Carbohydrates; Female; Gastric Mucosa; Gastrins; Glycosaminoglycans; Humans; Intubation, Gastrointestinal; Male; Mucus; Peptic Ulcer; Proteins; Pyrroles; Secretory Rate; Stress, Psychological | 1969 |
Experimental production of gastric and duodenal lesions by administration of 3-beta-aminoethyl 1,2,4-triazole.
Topics: Administration, Oral; Amines; Animals; Duodenal Ulcer; Duodenum; Fasting; Gastric Mucosa; Guinea Pigs; Injections, Intravenous; Male; Peptic Ulcer; Pylorus; Pyrroles; Rats; Stomach; Triazoles | 1970 |