pyrroles has been researched along with Osteoarthritis of Knee in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (40.00) | 29.6817 |
| 2010's | 8 (53.33) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, M; Martel-Pelletier, J; Pelletier, JP; Rahman, P; Randell, EW; Zhai, G | 1 |
| Kim, H; Kim, SJ; Lee, D | 1 |
| Deodhar, A | 1 |
| Bonanno, G; Di Cesare Mannelli, L; Fariello, RG; Farina, C; Ghelardini, C; Milanese, M; Misiano, P; Pittaluga, A | 1 |
| Arito, M; Beppu, M; Endo, W; Kato, T; Koizumi, H; Kurokawa, MS; Okamoto, K; Omoteyama, K; Suematsu, N | 1 |
| Abram, F; Beaulieu, AD; Bias, P; Choquette, D; Dorais, M; Haraoui, B; Laufer, S; Martel-Pelletier, J; Pelletier, JP; Raynauld, JP; Vignon, E | 1 |
| Abram, F; Bias, P; Choquette, D; Dorais, M; Emmert, KH; Haraoui, B; Laufer, S; Martel-Pelletier, J; Pelletier, JP; Raynauld, JP | 1 |
| Malizos, KN; Poultsides, L; Simopoulou, T; Tsezou, A | 1 |
| Abram, F; Caron, J; Choquette, D; Dorais, M; Haraoui, B; Martel-Pelletier, J; Mineau, F; Pelletier, JP; Raynauld, JP | 1 |
| Abram, F; Dorais, M; Martel-Pelletier, J; Pelletier, JP; Raynauld, JP; Wildi, LM | 1 |
| Abram, F; Choquette, D; Dorais, M; Haraoui, B; Martel-Pelletier, J; Pelletier, JP; Raynauld, JP; Wildi, LM | 1 |
| Boileau, C; Fahmi, H; Laufer, S; Lavigne, M; Martel-Pelletier, J; Pelletier, JP; Tardif, G | 1 |
| Fernandes, JC; Manacu, CA; Martel-Pelletier, J; Mitrovic, DR; Moldovan, F; Pelletier, JP; Roy-Beaudry, M; Shipkolye, FS | 1 |
| Guévremont, M; Laufer, S; Marcouiller, P; Martel-Pelletier, J; Pelletier, JP; Ranger, P; Reboul, P | 1 |
| Boileau, C; Brunet, J; Laufer, S; Martel-Pelletier, J; Moreau, M; Pelletier, JP | 1 |
7 trial(s) available for pyrroles and Osteoarthritis of Knee
| Article | Year |
|---|---|
Serum lysophosphatidylcholines to phosphatidylcholines ratio is associated with symptomatic responders to symptomatic drugs in knee osteoarthritis patients.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Cyclooxygenase Inhibitors; Female; Humans; Lysophosphatidylcholines; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Phosphatidylcholines; Pyrroles; Treatment Outcome | 2019 |
A 12 week, randomized, double-blind, placebo-controlled clinical trial for the evaluation of the efficacy and safety of HT083 on mild osteoarthritis.
Topics: Adult; Aged; Analgesics; Animals; Anti-Inflammatory Agents; Arthralgia; Commiphora; Double-Blind Method; Female; Humans; Indoles; Inflammation; Male; Medicine, Chinese Traditional; Middle Aged; Osteoarthritis, Knee; Paeonia; Placebos; Pyrroles; Republic of Korea; Rodentia; Safety; Treatment Outcome; Visual Analog Scale | 2020 |
Protective effects of licofelone, a 5-lipoxygenase and cyclo-oxygenase inhibitor, versus naproxen on cartilage loss in knee osteoarthritis: a first multicentre clinical trial using quantitative MRI.
Topics: Aged; Antirheumatic Agents; Cartilage, Articular; Chi-Square Distribution; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Knee Joint; Lipoxygenase Inhibitors; Magnetic Resonance Imaging; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Pain Measurement; Pyrroles; Radiography; Treatment Outcome | 2009 |
Analysis of the precision and sensitivity to change of different approaches to assess cartilage loss by quantitative MRI in a longitudinal multicentre clinical trial in patients with knee osteoarthritis.
Topics: Cartilage, Articular; Double-Blind Method; Female; Follow-Up Studies; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Pyrroles; Sensitivity and Specificity | 2008 |
Decrease in serum level of matrix metalloproteinases is predictive of the disease-modifying effect of osteoarthritis drugs assessed by quantitative MRI in patients with knee osteoarthritis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; C-Reactive Protein; Cartilage, Articular; Drug Monitoring; Female; Humans; Magnetic Resonance Imaging; Male; Matrix Metalloproteinases; Middle Aged; Naproxen; Osteoarthritis, Knee; Pyrroles; Severity of Illness Index; Treatment Outcome | 2010 |
Relationship between bone marrow lesions, cartilage loss and pain in knee osteoarthritis: results from a randomised controlled clinical trial using MRI.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Bone Marrow Diseases; Cartilage, Articular; Cyclooxygenase Inhibitors; Epidemiologic Methods; Female; Humans; Knee Joint; Magnetic Resonance Imaging; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Pain; Pain Measurement; Pyrroles | 2010 |
Risk factors predictive of joint replacement in a 2-year multicentre clinical trial in knee osteoarthritis using MRI: results from over 6 years of observation.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Knee; C-Reactive Protein; Disease Progression; Epidemiologic Methods; Female; Humans; Knee Joint; Magnetic Resonance Imaging; Male; Menisci, Tibial; Middle Aged; Naproxen; Osteoarthritis, Knee; Prognosis; Pyrroles; Tibial Meniscus Injuries | 2011 |
8 other study(ies) available for pyrroles and Osteoarthritis of Knee
| Article | Year |
|---|---|
Update in rheumatology: evidence published in 2012.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antirheumatic Agents; Antiviral Agents; Arthritis; Arthritis, Gouty; Arthritis, Rheumatoid; Autoimmune Diseases; Bacterial Infections; Calcitonin; Colchicine; Cryoglobulinemia; Death, Sudden, Cardiac; Drug Resistance, Viral; Enzyme Inhibitors; Female; Gout; Gout Suppressants; Hand Joints; Hepatitis C, Chronic; Humans; Hyperuricemia; Immunologic Factors; Janus Kinase 3; Male; Myocardial Infarction; Neoplasms; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Practice Guidelines as Topic; Protein Precursors; Pyrimidines; Pyrroles; Registries; Tumor Necrosis Factor-alpha | 2013 |
Broad spectrum and prolonged efficacy of dimiracetam in models of neuropathic pain.
Topics: Analysis of Variance; Animals; Anti-Retroviral Agents; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Hyperalgesia; Imidazoles; Male; Neuralgia; Osteoarthritis, Knee; Paclitaxel; Pain Measurement; Pain Threshold; Physical Stimulation; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Vincristine; Weight-Bearing | 2014 |
Effects of tofacitinib on nucleic acid metabolism in human articular chondrocytes.
Topics: Aged; Aged, 80 and over; AMP Deaminase; Blotting, Western; Cells, Cultured; Chondrocytes; Female; Gene Expression Regulation; Humans; Janus Kinase 3; Male; Nucleic Acids; Osteoarthritis, Knee; Piperidines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA | 2015 |
Protective effect of atorvastatin in cultured osteoarthritic chondrocytes.
Topics: Aged; Aged, 80 and over; Aggrecans; Atorvastatin; Cartilage, Articular; Cells, Cultured; Chondrocytes; Collagen Type II; Dose-Response Relationship, Drug; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-1beta; Knee Joint; Male; Matrix Metalloproteinase 13; Middle Aged; Osteoarthritis, Knee; Pyrroles | 2010 |
The regulation of human MMP-13 by licofelone, an inhibitor of cyclo-oxygenases and 5-lipoxygenase, in human osteoarthritic chondrocytes is mediated by the inhibition of the p38 MAP kinase signalling pathway.
Topics: Acetates; Aged; Cells, Cultured; Chondrocytes; Collagenases; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Humans; Interleukin-1; Lipoxygenase Inhibitors; MAP Kinase Signaling System; Matrix Metalloproteinase 13; Middle Aged; Osteoarthritis, Knee; Promoter Regions, Genetic; Pyrroles; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic | 2005 |
Endothelin-1 in osteoarthritic chondrocytes triggers nitric oxide production and upregulates collagenase production.
Topics: Aminoquinolines; Apoptosis; Carbazoles; Cartilage, Articular; Cells, Cultured; Chondrocytes; Collagenases; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Endothelin-1; Enzyme Induction; Female; Guanylate Cyclase; Humans; Imidazoles; Indoles; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 1; Matrix Metalloproteinase 13; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type II; Osteoarthritis, Knee; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Processing, Post-Translational; Pyridines; Pyrroles; Signal Transduction | 2005 |
Leukotriene and prostaglandin synthesis pathways in osteoarthritic synovial membranes: regulating factors for interleukin 1beta synthesis.
Topics: Acetates; Aged; Arachidonic Acid; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; In Vitro Techniques; Leukotriene B4; Lipopolysaccharides; Male; Masoprocol; Naproxen; Osteoarthritis, Knee; Pyrroles; Signal Transduction; Synovial Membrane | 2005 |
Licofelone reduces progression of structural changes in a canine model of osteoarthritis under curative conditions: effect on protease expression and activity.
Topics: Acetates; Animals; Anterior Cruciate Ligament; Cartilage, Articular; Collagenases; Disease Models, Animal; Disease Progression; Dogs; Enzyme Inhibitors; Metalloproteases; Osteoarthritis, Knee; Pyrroles; Stifle | 2006 |