pyrroles has been researched along with Neuralgia in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (16.00) | 29.6817 |
| 2010's | 18 (72.00) | 24.3611 |
| 2020's | 2 (8.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ding, X; Fan, X; Han, J; Ning, L; Tang, S; Wang, C | 1 |
| Bantreil, X; Bojarski, AJ; Canale, V; Chaumont-Dubel, S; Courteix, C; Drop, M; Eschalier, A; Jacquot, F; Lamaty, F; Lamoine, S; Mahoro, GU; Marin, P; Martinez, J; Masurier, N; Nosalska, K; Pawłowski, M; Pękala, E; Piska, K; Satała, G; Subra, G; Słoczyńska, K; Walczak, M; Zajdel, P | 1 |
| Di Cesare Mannelli, L; Farina, C; Ghelardini, C; Maresca, M; Micheli, L; Scherz, MW | 1 |
| Leánez, S; Pol, O; Redondo, A; Riego, G | 1 |
| Asahi, K; Endoh, T; Fuchino, K; Horiguchi, T; Jikihara, S; Kai, H; Kameyama, T; Kanda, Y; Kurihara, N; Ogawa, M; Oohara, M; Shimada, S; Shinohara, S; Tada, Y; Takahara, Y; Takeyama, C; Tamura, N; Taniguchi, E; Tobinaga, H; Yagi, S; Yamamoto, S | 1 |
| Choi, HY; Jang, C; Lee, JY; Lee, KT; Park, CS; Youn, I; Yune, TY | 1 |
| Bowen, CA; Fang, X; Heffernan, ML; Hopkins, SC; Large, TH; Spanswick, DC; Spear, KL; Varney, MA; Wei, H; Zhao, FY | 1 |
| Antunes, F; Barreiro, EJ; Fraga, CA; Mendes, TC; Nascimento, NM; Sudo, RT; Trachez, MM; Zapata-Sudo, G | 1 |
| Deng, L; Guindon, J | 1 |
| Balaganur, V; Kant, V; Kumar, D; Lingaraju, MC; More, AS; Pathak, NN; Tandan, SK | 1 |
| Gillon, JT; Lowden, MR; Smith, SE | 1 |
| Bonanno, G; Di Cesare Mannelli, L; Fariello, RG; Farina, C; Ghelardini, C; Milanese, M; Misiano, P; Pittaluga, A | 1 |
| Balaganur, V; Kant, V; Kumar, D; Latief, N; Lingaraju, MC; More, AS; Pathak, NN; Tandan, SK | 1 |
| Di Cesare Mannelli, L; Farina, C; Ghelardini, C; Maresca, M; Scherz, MW | 1 |
| Bujalska-Zadrożny, M; Dawidowski, M; de Cordé, A; Kleczkowska, P; Kogut, E | 1 |
| Keppel Hesselink, JM | 1 |
| Almqvist, PM; Finnerup, NB; Gormsen, L; Jensen, TS | 1 |
| Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K | 1 |
| Chen, Y; Wang, ZJ; Yang, C | 1 |
| Carmeliet, P; Daniels, A; Dhondt, J; Lambrechts, D; Meert, T; Nuydens, R; Peeraer, E; Pintelon, I; Poesen, K; Timmermans, JP; Verheyen, A | 1 |
| Hervera, A; Leánez, S; Motterlini, R; Negrete, R; Pol, O | 1 |
| Kato, H; Narita, M; Oe, K; Shibasaki, M; Suzuki, T; Yajima, Y; Yamazaki, M | 1 |
| Farina, C; Gagliardi, S; Ghelardini, C; Martinelli, M; Norcini, M; Parini, C; Petrillo, P; Ronzoni, S | 1 |
| Bettelini, L; Corsi, M; Fasdelli, N; Maraia, G; Quartaroli, M | 1 |
| Wauters, M | 1 |
1 trial(s) available for pyrroles and Neuralgia
| Article | Year |
|---|---|
The efficacy of the AMPA receptor antagonist NS1209 and lidocaine in nerve injury pain: a randomized, double-blind, placebo-controlled, three-way crossover study.
Topics: Adult; Aged; Analgesia; Anesthetics, Local; Chronic Disease; Cross-Over Studies; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Humans; Hyperalgesia; Infusions, Intravenous; Lidocaine; Male; Middle Aged; Neuralgia; Pain Measurement; Peripheral Nerve Injuries; Peripheral Nerves; Peripheral Nervous System Diseases; Pyrroles; Receptors, AMPA; Receptors, Kainic Acid; Tetrahydroisoquinolines; Time Factors; Treatment Outcome; Young Adult | 2009 |
24 other study(ies) available for pyrroles and Neuralgia
| Article | Year |
|---|---|
Role of TRPV4-P2X7 Pathway in Neuropathic Pain in Rats with Chronic Compression of the Dorsal Root Ganglion.
Topics: Animals; Ganglia, Spinal; Hyperalgesia; Leucine; Male; Morpholines; Nerve Compression Syndromes; Neuralgia; Purinergic P2X Receptor Antagonists; Pyrroles; Rats, Wistar; Receptors, Purinergic P2X7; Rosaniline Dyes; Signal Transduction; Sulfonamides; TRPV Cation Channels | 2021 |
Neuropathic pain-alleviating activity of novel 5-HT
Topics: Animals; Cell Line; Dose-Response Relationship, Drug; Humans; Male; Molecular Structure; Neuralgia; Pyrroles; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship | 2021 |
A rat model of FOLFOX-induced neuropathy: effects of oral dimiracetam in comparison with duloxetine and pregabalin.
Topics: Administration, Oral; Animals; Disease Models, Animal; Duloxetine Hydrochloride; Fluorouracil; Humans; Imidazoles; Neuralgia; Pregabalin; Pyrroles; Rats; Rats, Sprague-Dawley | 2017 |
Mechanism implicated in the anti-allodynic and anti-hyperalgesic effects induced by the activation of heme oxygenase 1/carbon monoxide signaling pathway in the central nervous system of mice with neuropathic pain.
Topics: Animals; Carbon Monoxide; Central Nervous System; Gene Expression Regulation; Heme Oxygenase-1; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Neuralgia; Organometallic Compounds; Pyrazines; Pyrroles; Sciatic Nerve; Signal Transduction | 2018 |
Pyrrolinone derivatives as a new class of P2X3 receptor antagonists Part 2: Discovery of orally bioavailable compounds.
Topics: Administration, Oral; Biological Availability; Drug Discovery; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Neuralgia; Purinergic P2X Receptor Antagonists; Pyrroles; Receptors, Purinergic P2X3; Structure-Activity Relationship | 2019 |
Inhibition of COX-2 alleviates lumbar spinal stenosis-induced chronic mechanical allodynia in rats.
Topics: Animals; Cauda Equina; Celecoxib; Chronic Pain; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytokines; Dinoprostone; Hyperalgesia; Lumbar Vertebrae; Macrophages; Male; Neuralgia; Pyrroles; Rats, Sprague-Dawley; Spinal Stenosis | 2019 |
Pharmacodynamic effects of a D-amino acid oxidase inhibitor indicate a spinal site of action in rat models of neuropathic pain.
Topics: Amines; Analgesics; Anesthesia; Animals; Behavior, Animal; Constriction, Pathologic; Cyclohexanecarboxylic Acids; D-Amino-Acid Oxidase; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Freund's Adjuvant; Furans; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Ligation; Male; Neuralgia; Physical Stimulation; Pyrroles; Rats; Rats, Sprague-Dawley; Serine; Spinal Cord; Spinal Nerves | 2013 |
Antihyperalgesic effects of a novel muscarinic agonist (LASSBio-873) in spinal nerve ligation in rats.
Topics: Analgesics; Animals; Hyperalgesia; Male; Muscarinic Agonists; Neuralgia; Pain Measurement; Peripheral Nerve Injuries; Pyrazoles; Pyridines; Pyrroles; Rats; Rats, Wistar; Receptor, Muscarinic M2; Spinal Nerves | 2013 |
Muscarinic agonists in the treatment of neuropathic pain: a novel finding.
Topics: Animals; Male; Muscarinic Agonists; Neuralgia; Peripheral Nerve Injuries; Pyrazoles; Pyridines; Pyrroles; Spinal Nerves | 2013 |
Antihyperalgesic and anti-inflammatory effects of atorvastatin in chronic constriction injury-induced neuropathic pain in rats.
Topics: Analgesia; Animals; Anti-Inflammatory Agents; Atorvastatin; Constriction; Dinoprostone; Disease Models, Animal; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-1beta; Male; Matrix Metalloproteinase 2; Nerve Growth Factor; Neuralgia; Pain Measurement; Pyrroles; Rats; Rats, Wistar; Sciatic Nerve; Spinal Cord; Tumor Necrosis Factor-alpha | 2013 |
Atorvastatin as novel treatment for neuropathic pain: a case report.
Topics: Analgesics; Atorvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Neuralgia; Phantom Limb; Pyrroles; Treatment Outcome | 2013 |
Broad spectrum and prolonged efficacy of dimiracetam in models of neuropathic pain.
Topics: Analysis of Variance; Animals; Anti-Retroviral Agents; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Hyperalgesia; Imidazoles; Male; Neuralgia; Osteoarthritis, Knee; Paclitaxel; Pain Measurement; Pain Threshold; Physical Stimulation; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Vincristine; Weight-Bearing | 2014 |
Atorvastatin attenuates neuropathic pain in rat neuropathy model by down-regulating oxidative damage at peripheral, spinal and supraspinal levels.
Topics: Animals; Antioxidants; Atorvastatin; Down-Regulation; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperalgesia; Male; Neuralgia; Oxidative Stress; Pyrroles; Rats, Wistar; Sciatic Nerve; Spinal Cord | 2014 |
A model of neuropathic pain induced by sorafenib in the rat: Effect of dimiracetam.
Topics: Analgesics; Analysis of Variance; Animals; Antineoplastic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Imidazoles; Male; Neuralgia; Niacinamide; Pain Measurement; Pain Threshold; Phenylurea Compounds; Pyrroles; Rats; Rats, Sprague-Dawley; Reaction Time; Sorafenib; Time Factors | 2015 |
Antinociceptive activity of intraperitoneally administered novel and potent anticonvulsive compound, CY-PROLL-SS, in animal neuropathic pain models.
Topics: Analgesics; Animals; Anticonvulsants; Disease Models, Animal; Injections, Intraperitoneal; Male; Neuralgia; Pain Measurement; Pyrazines; Pyrroles; Rats; Streptozocin | 2016 |
NS1209/SPD 502, A Novel Selective AMPA Antagonist for Stroke, Neuropathic Pain or Epilepsy? Drug Development Lessons Learned.
Topics: Animals; Clinical Trials as Topic; Drug Evaluation, Preclinical; Epilepsy; Humans; Neuralgia; Pyrroles; Receptors, AMPA; Stroke; Tetrahydroisoquinolines; Treatment Outcome | 2017 |
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship | 2010 |
Proteinase-activated receptor 2 sensitizes transient receptor potential vanilloid 1, transient receptor potential vanilloid 4, and transient receptor potential ankyrin 1 in paclitaxel-induced neuropathic pain.
Topics: Analysis of Variance; Anilides; Animals; Ankyrins; Antineoplastic Agents, Phytogenic; Capsaicin; Carbazoles; Central Nervous System; Cinnamates; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Estrenes; Gene Expression Regulation; Hyperalgesia; Male; Mice; Mice, Inbred ICR; Neuralgia; Oligopeptides; Paclitaxel; Pain Measurement; Physical Stimulation; Protein Kinase C; Pyrroles; Pyrrolidinones; Receptor, PAR-2; Sulfonamides; Time Factors; TRPV Cation Channels; Tryptases; Type C Phospholipases | 2011 |
Systemic anti-vascular endothelial growth factor therapies induce a painful sensory neuropathy.
Topics: Animals; Antibodies, Neutralizing; Behavior, Animal; Ganglia, Spinal; Indoles; Mice; Mice, Transgenic; Neuralgia; Neurons; Paclitaxel; Pain Measurement; Polyneuropathies; Protein Kinase Inhibitors; Pyrroles; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2012 |
Carbon monoxide reduces neuropathic pain and spinal microglial activation by inhibiting nitric oxide synthesis in mice.
Topics: Animals; Carbon Monoxide; CD11b Antigen; CD11c Antigen; Enzyme Induction; Ganglia, Spinal; Gene Expression Regulation, Enzymologic; Gene Knockout Techniques; Heme Oxygenase-1; Male; Mice; Microglia; Neuralgia; Nitric Oxide; Nitric Oxide Synthase Type II; Organometallic Compounds; Pyrazines; Pyrroles; Sciatic Nerve; Spinal Cord | 2012 |
Implication of spinal protein kinase C in the suppression of morphine-induced rewarding effect under a neuropathic pain-like state in mice.
Topics: Analgesics, Opioid; Animals; Chronic Disease; Disease Models, Animal; Enzyme Inhibitors; Indoles; Ligation; Male; Mice; Mice, Inbred ICR; Morphine; Morphine Dependence; Neuralgia; Protein Kinase C; Pyrroles; Reward; Sciatic Neuropathy; Spinal Cord; Up-Regulation | 2004 |
Synthesis and biological evaluation of novel dimiracetam derivatives useful for the treatment of neuropathic pain.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Imidazoles; Neuralgia; Pain Threshold; Pyrroles; Rats; Structure-Activity Relationship | 2008 |
GV196771A, an NMDA receptor/glycine site antagonist, attenuates mechanical allodynia in neuropathic rats and reduces tolerance induced by morphine in mice.
Topics: Animals; Behavior, Animal; Binding Sites; Constriction, Pathologic; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Excitatory Amino Acid Antagonists; Glycine; Indoles; Ligation; Male; Mice; Morphine; Narcotics; Neuralgia; Pain; Pain Measurement; Pain Threshold; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sciatic Nerve; Stress, Mechanical | 2001 |
[Studies of the therapeutic effectiveness of clopirac in non articular rheumatism (author's transl)].
Topics: Back Pain; Humans; Neuralgia; Periarthritis; Pyrroles; Rheumatic Diseases; Sciatic Nerve; Tendinopathy | 1975 |