pyrroles has been researched along with Nerve Degeneration in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 7 (41.18) | 29.6817 |
| 2010's | 6 (35.29) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Berve, K; Groh, J; Martini, R; West, BL | 1 |
| Eto, K; Kashiwagi, K; Koizumi, S; Nabekura, J; Ohno, N; Shinozaki, Y; Takeda, A; Wake, H | 1 |
| Abdel-Aziz, AK; Helwa, R; Mantawy, EM; Said, RS | 1 |
| Chopp, M; Han, Y; Karki, K; Knight, RA; Ledbetter, KA; Seyfried, DM; Yang, D; Zhang, J | 1 |
| Chen, CJ; Cheng, FC; Ho, SP; Ou, YC; Pan, HC; Yang, DY | 1 |
| Abe, K; Deguchi, K; Deguchi, S; Ikeda, Y; Kawai, H; Kurata, T; Matsuura, T; Ohta, Y; Omote, Y; Yamashita, T | 1 |
| Eriksson, H; Georgievska, B; Poewe, W; Stefanova, N; Wenning, GK | 1 |
| Allen, DD; Geldenhuys, WJ; Jones-Higgins, MR; Lockman, JA; Patrick, JD; Van der Schyf, CJ | 1 |
| Barbosa, E; Pannu, R; Singh, AK; Singh, I | 1 |
| Khan, S; Plamondon, H | 1 |
| Holmin, S; Risling, M; Sköld, MK | 1 |
| Guyton, JR; Laskowitz, DT; Lynch, JR; Mace, B; Song, P; Wang, H; Warner, DS; Yang, HJ; Yates, RB | 1 |
| Chen, J; Chopp, M; Goussev, A; Jiang, H; Li, Y; Lu, C; Lu, D; Mahmood, A; Qu, C; Schallert, T | 1 |
| Chu, K; Han, Z; Hong, NH; Im, WS; Jung, KH; Kang, L; Kim, M; Kim, MW; Lee, ST; Park, JE | 1 |
| Kim, PJ; Markesbery, WR; Montine, KS; Montine, TJ; Olson, SJ | 1 |
| Hall, ED; Smith, SL | 1 |
| Aldskogius, H; Mattsson, P; Svensson, M | 1 |
17 other study(ies) available for pyrroles and Nerve Degeneration
| Article | Year |
|---|---|
Sex- and region-biased depletion of microglia/macrophages attenuates CLN1 disease in mice.
Topics: Aminopyridines; Animals; Brain; Disease Models, Animal; Female; Macrophages; Male; Mice; Microglia; Nerve Degeneration; Neuronal Ceroid-Lipofuscinoses; Neurons; Pyrroles; Retina; Sex Factors; T-Lymphocytes; Tomography, Optical Coherence | 2020 |
Microglia mediate non-cell-autonomous cell death of retinal ganglion cells.
Topics: Aminopyridines; Animals; Animals, Newborn; Calcium-Binding Proteins; Cell Death; Cells, Cultured; Cytokines; Excitatory Amino Acid Agonists; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microfilament Proteins; Microglia; N-Methylaspartate; Nerve Degeneration; Optic Nerve Injuries; Organic Chemicals; Pyrroles; Retinal Ganglion Cells; Signal Transduction; Transcription Factor Brn-3A; Tumor Necrosis Factor-alpha | 2018 |
The tyrosine kinase inhibitor, sunitinib malate, induces cognitive impairment in vivo via dysregulating VEGFR signaling, apoptotic and autophagic machineries.
Topics: Analysis of Variance; Animals; Antineoplastic Agents; Apoptosis; Autophagy; Avoidance Learning; Body Temperature; Body Weight; Cognition Disorders; Disease Models, Animal; Female; Indoles; Locomotion; Maze Learning; Mice; Nerve Degeneration; Prepulse Inhibition; Pyrroles; RNA, Messenger; Signal Transduction; Sunitinib; Vascular Endothelial Growth Factor Receptor-2 | 2016 |
Simvastatin and atorvastatin improve neurological outcome after experimental intracerebral hemorrhage.
Topics: Animals; Apoptosis; Atorvastatin; Biomarkers; Brain; Brain Infarction; Bromodeoxyuridine; Cerebral Hemorrhage; Cytoprotection; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Doublecortin Domain Proteins; Doublecortin Protein; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Microtubule-Associated Proteins; Nerve Degeneration; Neurogenesis; Neuronal Plasticity; Neuropeptides; Neuroprotective Agents; Pyrroles; Rats; Rats, Wistar; Regeneration; Simvastatin; Treatment Outcome | 2009 |
Neuroprotective effect of atorvastatin in an experimental model of nerve crush injury.
Topics: Animals; Atorvastatin; Blotting, Western; Caspases; Cell Membrane Permeability; Collagen; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; In Situ Nick-End Labeling; Lipid Peroxidation; Male; Nerve Crush; Nerve Degeneration; Nerve Regeneration; Neuroprotective Agents; Peroxidase; Pyrroles; Rats; Rats, Sprague-Dawley; Recovery of Function; Reverse Transcriptase Polymerase Chain Reaction; Sciatic Nerve; Signal Transduction | 2010 |
Protection against ischemic stroke damage by synergistic treatment with amlodipine plus atorvastatin in Zucker metabolic rat.
Topics: Amlodipine; Animals; Atorvastatin; Brain Ischemia; Calcium Channel Blockers; Disease Models, Animal; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Nerve Degeneration; Neuroprotective Agents; Pyrroles; Rats; Rats, Zucker; Stroke | 2011 |
Myeloperoxidase inhibition ameliorates multiple system atrophy-like degeneration in a transgenic mouse model.
Topics: Aged; alpha-Synuclein; Animals; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gliosis; Humans; Male; Mice; Mice, Transgenic; Microglia; Middle Aged; Motor Activity; Multiple System Atrophy; Nerve Degeneration; Peroxidase; Pyrimidinones; Pyrroles | 2012 |
NGP1-01, a multi-targeted polycyclic cage amine, attenuates brain endothelial cell death in iron overload conditions.
Topics: Amines; Animals; Apoptosis; Arabidopsis Proteins; Blood-Brain Barrier; Bridged-Ring Compounds; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Carrier Proteins; Cell Survival; Endothelial Cells; Iron Overload; Nerve Degeneration; Neuroprotective Agents; Pyrroles; Rats; Receptors, N-Methyl-D-Aspartate; Transcription Factors | 2012 |
Attenuation of acute inflammatory response by atorvastatin after spinal cord injury in rats.
Topics: Animals; Anticholesteremic Agents; Atorvastatin; Disease Models, Animal; Female; Gliosis; Heptanoic Acids; Interleukin-1; Motor Activity; Myelitis; Necrosis; Nerve Degeneration; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oligodendroglia; Oxidative Stress; Pyrroles; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord; Spinal Cord Injuries; Treatment Outcome; Tumor Necrosis Factor-alpha | 2005 |
The CRH1 antagonist CP154,526 failed to alter ischemia-induced neurodegeneration and spatial memory deficits in rats but inhibited behavioral activity in the novel open field.
Topics: Animals; Behavior, Animal; Cell Count; Dose-Response Relationship, Drug; Exploratory Behavior; Hippocampus; Ischemia; Male; Memory Disorders; Nerve Degeneration; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Spatial Behavior; Time Factors | 2006 |
Inhibition of vascular endothelial growth factor receptor 2 activity in experimental brain contusions aggravates injury outcome and leads to early increased neuronal and glial degeneration.
Topics: Angiogenesis Inhibitors; Animals; Brain Injuries; Cell Count; Cell Death; Disease Models, Animal; Female; Fluoresceins; Glial Fibrillary Acidic Protein; Immunosorbent Techniques; In Situ Hybridization; In Situ Nick-End Labeling; Indoles; Microtubule-Associated Proteins; Myelin-Associated Glycoprotein; Nerve Degeneration; Nerve Growth Factors; Neuroglia; Organic Chemicals; Pyrroles; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Time Factors; Vascular Endothelial Growth Factor Receptor-2 | 2006 |
Simvastatin and atorvastatin improve behavioral outcome, reduce hippocampal degeneration, and improve cerebral blood flow after experimental traumatic brain injury.
Topics: Animals; Anti-Inflammatory Agents; Atorvastatin; Brain Edema; Brain Injuries; Brain Ischemia; Cerebrovascular Circulation; Chemotaxis, Leukocyte; Cognition Disorders; Cytokines; Disease Models, Animal; Encephalitis; Endothelial Cells; Heptanoic Acids; Hippocampus; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neurons; Pyrroles; Recovery of Function; RNA, Messenger; Simvastatin; Treatment Outcome | 2007 |
Statins increase neurogenesis in the dentate gyrus, reduce delayed neuronal death in the hippocampal CA3 region, and improve spatial learning in rat after traumatic brain injury.
Topics: Animals; Atorvastatin; Brain Injuries; Cell Proliferation; Dentate Gyrus; Dose-Response Relationship, Drug; Heptanoic Acids; Hippocampus; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Maze Learning; Memory Disorders; Neovascularization, Physiologic; Nerve Degeneration; Nerve Regeneration; Neuronal Plasticity; Neurons; Neuroprotective Agents; Pyrroles; Rats; Rats, Wistar; Recovery of Function; Simvastatin; Stem Cells; Treatment Outcome | 2007 |
Atorvastatin attenuates mitochondrial toxin-induced striatal degeneration, with decreasing iNOS/c-Jun levels and activating ERK/Akt pathways.
Topics: Animals; Atorvastatin; Corpus Striatum; Disease Models, Animal; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Heptanoic Acids; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Mitochondria; Nerve Degeneration; Neurotoxins; Nitric Oxide Synthase Type II; Nitro Compounds; Propionates; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrroles; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley | 2008 |
4-hydroxy-2-nonenal pyrrole adducts in human neurodegenerative disease.
Topics: Adult; Aged; Aged, 80 and over; Aldehydes; Alzheimer Disease; Apolipoprotein E3; Apolipoprotein E4; Apolipoproteins E; Brain; DNA Adducts; Female; Genotype; Homozygote; Humans; Male; Middle Aged; Nerve Degeneration; Nervous System Diseases; Pyrroles | 1997 |
Tirilazad widens the therapeutic window for riluzole-induced attenuation of progressive cortical degeneration in an infant rat model of the shaken baby syndrome.
Topics: Age Factors; Animals; Battered Child Syndrome; Body Temperature; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Free Radical Scavengers; Glutamic Acid; Head Injuries, Closed; Humans; Hypoxia; Infant; Lipid Peroxidation; Male; Nerve Degeneration; Neuroprotective Agents; Pregnatrienes; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Riluzole; Time Factors | 1998 |
The novel pyrrolopyrimidine PNU-101033-E improves facial motor neuron survival following intracranial axotomy of the facial nerve in the adult rat.
Topics: Animals; Axotomy; Betamethasone; Cell Count; Cell Survival; Facial Nerve; Male; Motor Neurons; Nerve Degeneration; Neuroprotective Agents; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley | 1999 |