Page last updated: 2024-08-18

pyrroles and Metastase

pyrroles has been researched along with Metastase in 447 studies

Research

Studies (447)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (0.22)	18.7374
1990's	4 (0.89)	18.2507
2000's	89 (19.91)	29.6817
2010's	348 (77.85)	24.3611
2020's	5 (1.12)	2.80

Authors

Authors	Studies
Liu, XY; Xu, J; Zhang, H; Zhang, P	1
Cong, L; Dong, J; Ke, M; Li, Y; Lv, Y; Wang, X; Zhang, Z; Zhao, S; Zhu, Y	1
Alchami, F; Bale, C; Bezecny, P; Butler, R; Carucci, M; Casbard, A; Cox, C; Foxley, A; Howell, SJ; Joffe, J; Jones, RH; Madden, TA; Moon, S; Twelves, C; Venkitaraman, R; Waters, S	1
Abou-Alfa, GK; Al-Rajabi, R; Borad, MJ; Catenacci, DV; Dotan, E; Féliz, L; Gallinson, D; Hollebecque, A; Ji, T; Lihou, CF; Melisi, D; Murphy, AG; Oh, DY; Paulson, AS; Sahai, V; Vaccaro, G; Van Cutsem, E; Vogel, A; Zhen, H	1
Bahl, A; Birtle, AJ; Crabb, SJ; Downs, N; Dunkley, D; Elliott, T; Griffiths, G; Jagdev, S; Jones, RJ; Khoo, V; Kumar, S; Light, M; Martin, K; Marwood, E; Northey, J; Robinson, A; Rooney, C; Salinas-Souza, C; Shaw, E; Stephens, C; Sundar, S; Westbury, C; Whitehead, A; Wilding, S	1
Díaz Valle, D; García Caride, S; Marquina, G	1
Kubo, N; Takeuchi, N	1
Agarwal, N; Figlin, RA; Hariharan, S; Hutson, TE; Li, CX; Martini, JF; Motzer, RJ; Williams, JA	1
Ezz El Din, M	1
Apellániz-Ruiz, M; Böhringer, S; Boven, E; Castellano, D; Diekstra, MH; García-Donás, J; Gelderblom, H; Guchelaar, HJ; Mathijssen, RHJ; Rini, BI; Rodríguez-Antona, C; Roldán, JM; Swen, JJ	1
Cai, W; Chen, Y; Huang, J; Huang, Y; Kong, W; Zhang, J; Zhou, L	1
Blommestein, HM; De Groot, S; Kiemeney, LALM; Oosterwijk, E; Redekop, WK; Sleijfer, S; Uyl-de Groot, CA	1
Antón-Aparicio, L; Arranz, JA; Bayona, C; Bolós, MV; Castellano, D; Climent, MA; Espinosa, E; Esteban, E; Fernández Parra, E; Gallardo, E; Gallegos, I; García Donas, J; González Del Alba, A; Grande, E; Llinares, J; Maroto, JP; Méndez, MJ; Samaniego, L	1
Agarwal, N; Gill, DM; Vaishampayan, U	1
Cook, G; Goh, V; Kelly-Morland, C; Mallett, S; Montana, G; Nathan, P; Rudman, S	1
Balakrishnar, B; Chan, M; Coulter, S; Fox, P; Gebski, V; Gurney, H; Liddle, C; Sabanathan, D; Zhang, A	1
Bortlicek, Z; Buchler, T; Chloupková, R; Dusek, L; Fiala, O; Finek, J; Hornova, J; Kiss, I; Kopeckova, K; Kopecky, J; Lakomy, R; Melichar, B; Poprach, A; Slaby, O; Studentova, H; Svoboda, M; Vyzula, R; Zemanova, M	1
Cai, W; Chen, Y; Dong, B; Huang, J; Huang, Y; Kong, W; Xue, W; Zhang, J; Zhou, L	2
Mikami, Y; Murofushi, T; Suzuki, N; Tsuda, H; Yamaguchi, Y	1
Cárcano, FM; da Silva Oliveira, RJ; de Lima, MA; Morini Matushita, MA; Reis, RM; Ribeiro, GG; Scapulatempo-Neto, C; Viana, CR; Zucca, LE	1
Cuccarese, MF; Kim, E; Kohler, RH; Miller, MA; Pittet, MJ; Plotkin, AL; Prytyskach, M; Weissleder, R	1
'Aho, T; Armitage, JN; Eisen, T; Fife, K; Klatte, T; Matakidou, A; Riddick, AC; Sachdeva, M; Stewart, GD; Welsh, SJ	1
Ba, Y; Bai, YX; Bi, JW; Ding, KF; Feng, JP; Lei, J; Li, J; Lin, LZ; Liu, YP; Ma, LW; Shen, L; Shi, CM; Wang, D; Wang, JW; Wang, KM; Wu, CP; Wu, G; Xiong, JP; Xu, RH; Yang, Q; Yu, H	1
Asai, A; Matsunaga, N; Matsuo, T; Mitsunari, K; Miyata, Y; Mochizuki, Y; Ohba, K; Sakai, H; Yasuda, T	1
Cserháti, A; Kahán, Z; Kószó, R; Maráz, A; Révész, J; Szilágyi, É; Uhercsák, G; Varga, L; Varga, Z	1
Iizuka, J; Ishihara, H; Iwamoto, K; Kondo, T; Takagi, T; Tanabe, K; Yoshida, K	1
Aubé, J; Baserga, SJ; Bian, Y; Chen, W; Chow, E; Dextras, C; Fang, M; Farley, KI; Feldman, C; Ferrer, M; Frankowski, KJ; Goldberg, E; Griner, LM; Hu, D; Huang, H; Huang, S; Kandela, I; Kang, J; Khanolkar, O; Kim, HR; Knotts, Z; Kozlov, S; Lewandowska, MA; Li, D; Long, C; Marugan, JJ; Mazar, A; Meng, Z; Nagashima, K; Norton, J; Patnaik, S; Powers, AS; Quadri, HS; Rudloff, U; Sahagian, G; Schoenen, FJ; Shilatifard, A; Southall, N; Sultan, J; Sun, W; Teper, Y; Titus, S; Vilimas, T; Wang, C; Wen, Y; Xi, R; Zheng, W; Zhou, M	1
Aki, R; Ito, T; Matsushita, Y; Miyake, H; Motoyama, D; Otsuka, A; Sugiyama, T; Tamura, K	1
Chen, LJ; Li, BT; Mai, HX; Mei, GH; Tang, YY; Xu, XJ; Zhang, B; Zhao, FL	1
Alarcón, E; Armstrong, AC; Cheung, SYA; Corcoran, C; Cullberg, M; Davies, BR; de Bruin, EC; Foxley, A; Gómez Villanueva, A; Lindemann, JPO; López Chuken, YA; Maudsley, R; Moschetta, M; Oliveira, M; Outhwaite, E; Pass, M; Pérez-Fidalgo, JA; Philco, M; Rugman, P; Sablin, MP; Schiavon, G; Tamura, K; Turner, NC	1
Carr, TH; Citi, V; Cutts, R; de Bruin, EC; Fenwick, K; Garcia-Murillas, I; Hrebien, S; Kozarewa, I; Maudsley, R; McEwen, R; Oliveira, M; Ratnayake, J; Schiavon, G; Turner, N	1
Du, Y; Fang, J; Guo, X; Jin, Y; Liang, X; Lu, W; Sun, W; Tian, J; Yu, C; Zheng, J	1
Rongrong, S; Sun, S; Xiaowu, L; Yangmei, Z; Youwei, Z; Yuan, Y	1
Armeanu-Ebinger, S; Dewerth, A; Fuchs, J; Hoh, A; Lieber, J; Vogt, F	1
Berkers, J; Beuselinck, B; Claes, B; Couchy, G; Deplanque, G; Descazeaud, A; Elaidi, R; Gravis, G; Joly, F; Karadimou, A; Lambrechts, D; Lebret, T; Leclercq, NR; Lerut, E; Méjean, A; Molinié, V; Oudard, S; Paridaens, R; Patard, JJ; Schöffski, P; Teghom, C; van Poppel, H; Verkarre, V; Wolter, P; Zucman-Rossi, J	1
Boudou-Rouquette, P; Delongchamps, NB; Giroux, J; Goldwasser, F; Huillard, O; Mir, O; Peyromaure, M; Ropert, S; Tlemsani, C; Zerbib, M	1
Berger, J; Berkers, J; Beuselinck, B; Bigot, P; Claes, B; Couchy, G; de la Taille, A; Karadimou, A; Lambrechts, D; Lerut, E; Linassier, C; Méjean, A; Négrier, S; Oudard, S; Paridaens, R; Patard, JJ; Schöffski, P; Tourani, JM; Verkarre, V; Wolter, P; Zucman-Rossi, J	1
Adjei, AA; Belani, CP; Chow, LQ; Dy, GK; Fortin, C; Gupta, A; Jonker, DI; Laurie, SA; Nicholas, G; Park, JS; Patricia, D; Sbar, EI; Zhang, S	1
Albiges, L; Di Palma, M; Escudier, B; Fizazi, K; Levy, A; Loriot, Y; Menard, J	1
Armand, JP; Bahleda, R; Baselga, J; Berman, D; Calvo, E; Felip, E; Hanna, N; Harbison, CT; Herbst, RS; Kurland, JF; Laurie, SA; Park, JS; Pathak, AK; Shepherd, FA; Soria, JC; Vakkalagadda, B; Zhang, S	1
Artis, DR; Bollag, G; Bremer, R; Burton, EA; Carias, H; Habets, G; Hirth, P; Hurt, CR; Ibrahim, PN; Lin, P; Marimuthu, A; Matusow, B; Nespi, M; Nguyen, H; Nolop, K; Oh, A; Powell, B; Shellooe, R; Spevak, W; Tesch, GH; Tsang, G; West, BL; Wu, G; Zhang, C; Zhang, J; Zhang, KY; Zhang, Y	1
Bianconi, M; Bittoni, A; Burattini, L; Cascinu, S; Del Prete, M; Faloppi, L; Giampieri, R; Loretelli, C; Maccaroni, E; Minardi, D; Montironi, R; Muzzonigro, G; Nicoletti, S; Scartozzi, M	1
Bydlowski, SP; Chierice, GO; Ferreira, AK; Filho, OM; Freitas, VM; Levy, D; Maria, DA; Rici, RE; Ruiz, JL	1
Ahn, H; Ahn, JH; Ahn, S; Ahn, Y; Hong, JH; Kim, CS; Lee, DH; Lee, JL; Park, I; Park, K; Park, SJ; Song, C	1
Berney, D; Bex, A; Blank, C; Boleti, E; Chowdhury, S; Haanen, J; Jones, R; Kayani, I; Lim, L; Peters, J; Powles, T; Reynolds, AR; Sahdev, A; Shamash, J; Sharpe, K; Stewart, GD	1
Mayor, S	1
Brugia, M; Cerullo, C; Neri, B; Rangan, S; Rediti, M; Tassi, R; Vannini, A	1
Guerin, E; Kerbel, RS; Man, S; Xu, P	1
Calvani, N; Chiuri, V; Cinieri, S; Fedele, P; Gnoni, A; Lorusso, V; Maiello, E; Morelli, F; Orlando, L; Scavelli, C	1
Islam, M; Kumar, B; Sharma, S; Teknos, TN	1
Chen, CT; Chen, SH; Kao, J; Packer, SH; Schwartz, M; Sung, MW; Tong, CC	1
Akyol, M; Alacacioglu, A; Bayoglu, IV; Can, A; Demir, L; Dirican, A; Erten, C; Koeseoglu, M; Kucukzeybek, Y; Payzin, KB; Somali, I; Tarhan, MO; Yildiz, Y	1
Aline-Fardin, A; Bouchekioua, A; Cervera, P; Coppo, P; de Wever, O; Douay, L; Gaulard, P; Gespach, C; Jeziorowska, D; Louache, F; Mercher, T; Nyga, R; Scourzic, L; Solary, E; Vainchenker, W; Zhang, Y	1
Barrios, CH; Bukowski, R; Escudier, B; Fly, K; Gore, ME; Hutson, TE; Lin, X; Matczak, E; Motzer, RJ; Rini, BI	1
Alemany, I; Arranz, JA; Bellmunt, J; Castellano, DE; Climent, MA; Esteban, E; Font, A; Gallardo, E; Garcia-Donas, J; González Del Alba, A; Hernando, S; Leandro-García, LJ; Mellado, B; Moreno, F; Morente, M; Puente, J; Robledo, M; Rodríguez-Antona, C	1
Bamia, C; Bamias, A; Beuselinck, B; Chrisofos, M; de Guillebon, E; Dimopoulos, MA; Diosynopoulos, D; Elaidi, RT; Escudier, B; Fountzilas, G; Lang, H; Oudard, S; Papazisis, K; Stravodimos, K; Tzannis, K; Wolter, P	1
Bachelot, T; Blasinska-Morawiec, M; Capitain, O; Cognetti, F; Crown, JP; Davidson, N; Diéras, V; Fasching, PA; Fountzilas, G; Greil, R; Huang, X; Kern, KA; Kreienberg, R; Liedtke, C; Miller, WH; Paolini, J; Ramos, M; Romieu, G; Staroslawska, E; Tassell, V; Wildiers, H; Yardley, DA	1
Aprile, G; Belli, C; Bergamo, F; Ceraulo, D; Cereda, S; Danova, M; Di Lucca, G; Franceschi, E; Fugazza, C; Mambrini, A; Milella, M; Novarino, A; Passardi, A; Reni, M; Villa, E	1
Ingels, A; Nolley, R; Peehl, DM; Santos, J; Thong, AE; Valta, MP; Young, SR; Zhao, H	1
Soulières, D	1
Castiglioni, V; Cesca, M; Decio, A; Giavazzi, R; Rovida, A; Scanziani, E; Scarlato, V	1
Gong, K; He, ZS; Huang, LH; Jin, J; Li, XS; Shen, C; Song, G; Song, Y; Yu, W; Zhang, CJ; Zhang, Q; Zhang, Z; Zhao, J; Zhao, PJ; Zhao, Z; Zhou, LQ	1
Cataruozolo, PE; Cesari, R; Collier, M; Cortés, J; Curigliano, G; Elias, A; Goldhirsch, A; Huang, X; Kern, KA; Khosravan, R; Pivot, X	1
Kubota, Y; Makiyama, K; Nakaigawa, N; Nakamura, M; Sakata, R; Sano, F; Tatenuma, T; Yao, M	1
Ahn, JB; Kim, HR; Kim, HS; Kwon, WS; Lee, JH; Lim, SM; Park, HS; Rha, SY; Shin, SJ; Tanigawara, Y	1
Atkinson, BJ; Bathala, T; Corn, P; Jonasch, E; Kalra, S; Tannir, NM; Wang, X	1
Busch, C; de Wijn, R; Geisler, J; Kristensen, V; Lønning, PE; Ree, AH; Risberg, K; Røe, K; Tahiri, A	1
Korytowsky, B; Lechuga, MJ; Lin, X; Matczak, E; Molina, AM; Motzer, RJ; Wiltshire, R	1
Ebos, JM; Francia, G; Guerin, E; Kerbel, RS; Lee, CR; Man, S; Xu, P	1
Cho, IC; Chung, J; Joung, JY; Kwon, WA; Lee, KH; Nam, BH; Seo, HK; Yu, A	1
Alkiş, N; Bal, O; Demirci, A; Durnali, A; Ekinci, AŞ; Eşbah, O; Oksüzoğlu, B	1
Bastide, C; Bay, JO; Bruyere, F; Guy, L; Karsenty, G; Mahammedi, H	1
Bauer, S; Blay, JY; Gelderblom, H; Guchelaar, HJ; Hogendoorn, PC; Hohenberger, P; Kerst, JM; Leahy, M; Marreaud, S; Ouali, M; Ray-Coquard, I; Rutkowski, P; Seddon, BM; Sleijfer, S; van der Straaten, RJ; Weitman, SD	1
Arakawa-Todo, M; Hasegawa, T; Kajikawa, K; Kato, Y; Kobayashi, I; Matsuura, K; Nakamura, K; Nishikawa, G; Saito, H; Sumitomo, M; Tsukiyama, I; Yamada, Y; Yoshizawa, T; Zennami, K	1
Berger, R; Boursi, B; Carducci, MA; Eisenberger, MA; Gottfried, M; Hammers, H; Hayat, H; Ish-Shalom, M; Keizman, D; Kovel, S; Maimon, N; Mermershtain, W; Neumann, A; Peer, A; Pili, R; Rouvinov, K; Sella, A; Sinibaldi, V; Weitzen, R	1
Bortlicek, Z; Buchler, T; Dusek, L; Kiss, I; Kubackova, K; Lakomy, R; Melichar, B; Pavlik, T; Poprach, A; Svoboda, M; Vyzula, R	1
Atri, M; Bjarnason, GA; Burns, PN; Hudson, JM; Khalil, B; Kiss, A; Milot, LM; Williams, R	1
Bahl, A; Castellano, D; Chen, I; Chow Maneval, E; Daugaard, G; Gschwend, J; Houede, N; Jones, R; Laestadius, F; Lechuga, MJ; Maurina, T; Michaelson, MD; Ostler, P; Ou, YC; Oudard, S; Paolini, J; Saad, F; Sengeløv, L; Stenzl, A; Ullèn, A; Wang, SL	1
Berney, DM; Bharwani, N; Chowdhury, S; Dilks, P; Miquel, ME; Powles, T; Rockall, AG; Sahdev, A; Shawyer, A; Wilson, PD	1
Chatterjee, P; Kumar, R; Sikka, K	1
Arranz, JA; Bellmunt, J; Calvo, A; Carles, J; Castellano, D; Climent, MA; del Alba, AG; Esteban, E; Font, A; Gallardo, E; Garcia-Donas, J; Gurpide, A; Guruceaga, E; Hernandez, AG; Lopez-Picazo, JM; Lozano, MD; Martínez, E; Mellado, B; Moreno, F; Perez-Gracia, JL; Prior, C; Puente, J; Rodriguez-Antona, C; Suarez, C	1
Basaran, G; Cabuk, D; Dane, F; Korkmaz, T; Seber, S; Telli, F; Teomete, M; Turhal, S; Yumuk, PF	1
Bögemann, M; Herrmann, E; Hertle, L; Hoffmeister, I; Krabbe, LM; Moritz, R; Papavassilis, P; Thielen, B	1
Dreicer, R; Elson, P; Garcia, JA; Mittal, K; Najjar, YG; Rini, BI; Wood, L	1
Bachelot, T; Blay, JY; Cesari, R; Garcia-Saenz, JA; Gutierrez, M; Huang, X; Kern, KA; Khosravan, R; Kozloff, MF; Lluch, A; Pivot, X; Prady, C; Tassell, V; Verma, S; Wang, Z	1
Akin, O; Berger, MF; Brannon, AR; Chen, YB; Cheng, EH; Cunha, LF; Hakimi, AA; Hsieh, JJ; Liu, H; Motzer, RJ; Pham, CG; Reuter, VE; Russo, P; Sander, C; Schultz, N; Scott, SN; Socci, ND; Takeda, S; Viale, A; Voss, MH	1
Bushmakin, AG; Cappelleri, JC; Cella, D; Charbonneau, C; Davis, MP; Figlin, RA; Korytowsky, B; Matczak, E; Michaelson, MD; Motzer, RJ; Négrier, S; Sandin, R	1
Bertens, D; Desar, IM; Kessels, RP; Langenhuijsen, JF; Mulder, SF; Mulders, PF; Punt, CJ; van Herpen, CM; van Spronsen, DJ; Vissers, KC	1
Ambrosetti, D; Amiel, J; Gastaud, L; Grépin, R; Marsaud, A; Pagès, G; Pedeutour, F	1
Fujisawa, M; Furukawa, J; Harada, K; Miyake, H; Nishikawa, M; Tei, H	1
Aik, OT; Htun, TH; Lim, NK; Meng, LL; Razack, AH	1
Anastasiou, I; Bamia, C; Bamias, A; Beuselinck, B; Chrisofos, M; Constantinides, C; Deliveliotis, C; Dimopoulos, MA; Elaidi, TR; Escudier, B; Liontos, M; Mitropoulos, D; Oudard, S; Papatsoris, A; Stravodimos, K; Tzannis, K	1
Go, S; Hanasaki, T; Hashimoto, T; Higuchi, Y; Ito, N; Kanamaru, S; Kanematsu, A; Kawakita, M; Kono, Y; Makino, Y; Matsumoto, K; Nagasawa, S; Nakanishi, Y; Nojima, M; Shimatani, K; Shimizu, Y; Shiraishi, Y; Suzuki, T; Taoka, R; Togo, Y; Tsuchihashi, K; Utsunomiya, N; Yamamoto, S; Yo, T	1
Blomqvist, LK; Farnebo, J; Grybäck, P; Harmenberg, U; Laurell, A; Sandström, P; Ullén, A; Wersäll, P	1
Bolanča, A; Jakšić, B; Jazvić, M; Krilić, D; Kusić, Z; Kust, D; Murgić, J; Prpić, M	1
Cao, J; Hu, X; Lv, F; Wang, B; Wang, L; Wang, Z; Zhang, J	1
Doi, T; Naito, Y; Nishida, T	1
Albert, I; Ao-Baslock, A; Berger, MS; Blakely, LJ; Kazarnowicz, A; Kovacs, P; Langer, CJ; Moezi, MM; Pajkos, G; Pathak, AK; Ross, HJ; Schnyder, J; Schreeder, MT; Somfay, A; Zatloukal, P	1
Blacher, S; Calligaris, D; Cimino, J; De Pauw, E; De Tullio, P; Debois, D; Mari, B; Mazzucchelli, G; Noel, A; Paye, A; Primac, I; Sounni, NE; Truong, A	1
Anak, O; Barrios, CH; Bavbek, S; Beck, JT; Cheung, FY; Cosgriff, T; Falcon, S; Flaig, TW; Harker, WG; Kim, TM; Knox, JJ; Motzer, RJ; Niolat, J; Page, R; Patel, P; Pittman, K; Rha, SY; Sabbatini, R; Schiff, EM; Sellami, D; Srimuninnimit, V; Wang, X; Yadav, S	1
Berger, R; Boursi, B; Gottfried, M; Hayat, H; Keizman, D; Kovel, S; Livne-Segev, D; Maimon, N; Mermershtain, W; Neumann, A; Peer, A; Rouvinov, K; Sella, A; Weitzen, R	1
Czarnecka, AM; Rini, B; Szczylik, C	1
Kosaka, T; Mikami, S; Mizuno, R; Okada, Y; Oya, M; Saya, H	1
Acharyya, S; Chopra, A; Fay, AP; Haaland, B; Lopes, Gde L	1
Albanell, J; Bellmunt, J; Beltran, M; Bonfill, T; Carles, J; Gallardo, E; Galtes, S; Moya, I; Pons, F; Rodon, J; Suarez, C	1
Burattini, L; Caricato, M; Cascinu, S; Conti, A; Guida, FM; Santini, D; Santoni, M; Savini, A; Tonini, G; Zeppola, T	1
Chen, JS; Chen, TW; Chen, YY; Cheng, CT; Chiang, KC; Hsu, CC; Jan, YY; Liu, YY; Tsai, CY; Tseng, JH; Wu, CE; Yeh, CN; Yeh, TS	1
Buonomano, P; Camera, L; Circelli, L; Colao, A; Del Prete, M; Di Somma, C; Faggiano, A; Marciello, F; Marotta, V; Modica, R; Ramundo, V; Rubino, M; Sciammarella, C	1
Bagcchi, S	1
Attwood, K; Burns, P; Cruz-Munoz, WR; Ebos, JM; Hudson, JM; Jedeszko, C; Kerbel, RS; Lee, CR; Mastri, M; Tracz, A	1
Biziato, D; De Palma, M	1
Baldazzi, V; Carini, M; Lapini, A; Mazzanti, R; Tassi, R	1
Altinmakas, E; Aparicio, A; Campbell, MT; Corn, PG; Millikan, RE; Siefker-Radtke, AO; Tannir, NM; Wen, SJ; Xiao, L	1
Kume, H; Makino, K; Tomoishi, J; Yoda, K	1
Chan, A; Chau, NM; Chue, XP; Ho, HK; Kanesvaran, R; Tan, MH; Teo, YL; Wee, HL	1
Donskov, F; Fode, K; Geertsen, PF; Hermann, GG; Ibsen, R; Jensen, NV; Kjellberg, J; Soerensen, AV	1
Chan, A; Chau, NM; Hong, YW; Kanesvaran, R; Li, H; Lopes, G; Ng, QS; Tan, HS; Tan, MH; Tang, T; Tay, MH; Toh, CK; Wong, A; Yao, X	1
Bortlicek, Z; Buchler, T; Coufal, O; Dusek, L; Fiala, O; Kiss, I; Kubackova, K; Lakomy, R; Melichar, B; Pavlik, T; Poprach, A; Svoboda, M; Vyzula, R; Zemanova, M	1
Ito, T; Kutikov, A	1
Bianconi, M; Cascinu, S; Minardi, D; Muzzonigro, G; Quaresima, L; Santoni, M; Scartozzi, M	1
Bhatt, RS; Choueiri, TK; Hamnvik, OP; Kaymakcalan, MD; Lin, X; McKay, RR; Rodriguez, GE; Sabbisetti, VS; Simantov, R	1
Iqbal, Y; Malik, MF; Riaz, SK	1
Chen, L; Cui, X; Gan, S; Hong, Y; Huang, H; Huang, Y; Li, L; Liu, B; Pan, X; Xu, D; Ye, J; Zhou, Q	1
Bergh, J; Foukakis, T; Giorgetti, C; Hedayati, E; Jacobsson, H; Lindström, LS; Lövrot, J; Sandqvist, P; Xie, H	1
Bortlicek, Z; Buchler, T; Dusek, L; Kiss, I; Kubackova, K; Lakomy, R; Melichar, B; Pavlik, T; Poprach, A; Prausova, J; Svoboda, M; Vyzula, R	1
Chen, HM; Chen, SH; Coakley, BA; Divino, C; Eisenstein, S; Ferris, R; Gildener-Leapman, N; Kao, J; Ko, EC; Ma, G; Mandeli, J; Ozao, J; Pan, PY; Schwartz, M; Sung, M; Wang, LH	1
Atkins, MB; DiPaola, RS; Dutcher, JJ; Flaherty, KT; Haas, NB; Jewett, M; Kane, CJ; Ky, B; Manola, J; Uzzo, RG; Wilding, G; Wood, CG; Wood, L	1
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Beutel, G; Drewes, N; Ganser, A; Grünwald, V; Ivanyi, P; Kielstein, JT; Morgan, M; Pirr, J	1
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Bedke, J; Stühler, V	1
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Blay, JY; Reichardt, P	1
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Choueiri, TK; Hirsch, MS; Mosquera, JM	1
Kuczyk, MA; Merseburger, AS; Simon, A; Waalkes, S	1
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Lieber, ML; Shah, SN; Smith, AD	1
Kolb, MM; Kozloff, MF; Samant, M; Scappaticci, FA; Socinski, MA	1
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Haseke, N; Stadler, T; Staehler, M; Stief, CG; Zilinberg, K	1
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Fesler, MJ; Katta, A; Richart, JM; Tan, A; Vuong, G	1
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Bronstein, Y; Busaidy, NL; Cabanillas, ME; Feng, L; Hernandez, M; Lopez, A; Sherman, SI; Waguespack, SG; Williams, MD	1
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Arnold, D; Ravaud, A; Schmidinger, M; Szczylik, C; Wagstaff, J	1
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Fagin, JA; Pfister, DG; Tuttle, RM	1
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Fischer, BS; Gan, J; Ganapathi, R; Gong, J; Iyer, R; Masson, E; Mekhail, T; Patricia, D; Pursley, J; Williams, D	1
Fujisawa, M; Haraguchi, T; Miyake, H; Takenaka, A	1
Rini, B; Rixe, O	1
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Bauman, JE; Capell, PT; Carr, LL; Eaton, KD; Goulart, BH; Kell, EM; Mankoff, DA; Martins, RG	1
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Charbonneau, C; Sandin, R	1
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Fratto, ME; Imperatori, M; Santini, D; Tomao, F; Tonini, G; Vincenzi, B	1
Basappa, NS; Dreicer, R; Elson, P; Garcia, JA; Golshayan, AR; Rini, BI; Wood, L	1
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Li, H; Shi, GH; Wang, CF; Yang, LF; Yang, ZY; Yao, XD; Ye, DW; Zhang, HL; Zhang, SL; Zhu, Y	1
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Aubin, F; Blanke, CD	1
Board, R; Hawkins, R; O'Dwyer, J; Shablak, A	1
Alacacioglu, A; Camci, C; Dikilitas, M; Er, O; Kalender, ME; Sagol, O; Sari, I; Sevinc, A; Soyuer, I; Yilmaz, U	1
Postema, PG; Regeer, MV; Richel, DJ; Stroes, ES; van der Valk, PR	1
Agresta, S; Antonia, S; Calitri, CE; Chiappori, A; D'Amato, G; Dean, M; Garrett, C; Han, G; Mahmood, ST; Schell, MJ; Vigil, CE; Zhao, X	1
Ikushima, H; Ishizu, A; Kamishima, T; Kanayama, H; Nonomura, K; Otsuka, N; Shimizu, C; Shinohara, N; Takahashi, M	1
Fischer, R; Jaehde, U; Kanefendt, F; Kinzig, M; Lindauer, A; Moritz, B; Mross, K; Scheulen, ME; Sörgel, F; Strumberg, D	1
Bex, A; Chowdhury, S; Hutson, T; Jones, R; Lim, L; Mantle, M; Nathan, P; Powles, T	1
Andreadis, C; Bamias, A; Dimopoulos, M; Karadimou, A; Kontovinis, L; Laschos, K; Papazisis, K; Paraskevopoulos, P	1
Cohen, P; Finke, J; Ireland, J; Ko, J; Rayman, P; Rini, B	1
Bradshaw, MJ; Cheville, JC; Croghan, GA	1
Diebold, J; Hirschmann, A; Rössle, M	1
Amato, RJ; de Belin, J; Goonewardena, M; Harrop, R; Hawkins, RE; Kaufman, HL; Kelleher, M; McDonald, M; Naylor, S; Shingler, WH; Treasure, P	1
Bello, CL; Ravaud, A	1
Kamiya, K; Kikuchi, H; Konno, H; Miyazaki, S; Ohta, M; Sakaguchi, T; Setoguchi, T; Yamamoto, M	1
Canipari, C; Chen, K; Duh, MS; Imarisio, I; Neary, M; Paglino, C; Porta, C	1
Aranda, E; Carrato, A; Chau, I; Countouriotis, AM; Cunningham, D; Guillen-Ponce, C; Iveson, TJ; Ramos, FJ; Ruiz-Garcia, A; Saunders, MP; Starling, N; Tabernero, J; Tursi, JM; Vázquez-Mazón, F; Wei, G	1
Fujisawa, M; Kusuda, Y; Miyake, H; Terakawa, T	1
Duh, MS; Feinberg, BA; Fortner, B; Gilmore, J; Jolly, P; Neary, MP; Scott, J; Wang, ST	1
Karakiewicz, PI; Maurin, C; Perrotte, P; Sun, M; Thuret, R	1
Atri, M; Bjarnason, GA; Burns, PN; Hudson, JM; Lloyd, BA; Lueck, G; Milot, L; Sureshkumar, AR; Williams, R	1
Ahn, JB; Chung, HC; Jeung, HC; Jung, M; Kim, HR; Rha, SY; Roh, JK; Shin, SJ	1
Buonerba, C; Casciano, R; De Placido, S; Di Lorenzo, G; Liu, Z; Malangone, E; Sherman, S; Wang, X; Willet, J	1
Antonarakis, ES; Carducci, MA; Eisenberger, MA; Hammers, H; Huang, P; Keizman, D; Kim, JJ; Pili, R	1
Greil, R; Grundbichler, M; Kappacher, A; Mlineritsch, B; Moik, M; Ressler, S; Rosenlechner, S	1
Chang, TT; Chen, TJ; Hsu, JC; Jen, YC; Li, WS; Lu, CK; Lu, IH; More, SV	1
Albain, KS; Besse, B; Blais, N; Chao, RC; Gervais, R; Hainsworth, JD; Hamm, JT; Kim, ST; Laskin, J; Lipton, A; Masters, GA; Natale, RB; Page, RD; Selaru, P	1
Chatellier, G; Cuenod, CA; Faraggi, M; Fournier, L; Hindié, E; Huchet, V; Hugonnet, F; Itti, E; Medioni, J; Oudard, S; Smadja, C	1
du Parcq, J; Fisher, C; Larkin, JM; Livni, N; Thway, K	1
Chan, AL; Leung, HW	1
Ahn, HK; Kang, WK; Lee, J; Lee, S; Lim, HY; Park, JO; Park, SH; Park, YS; Sun, JM	1
Bernhard, JC; De Clermont, H; Gross-Goupil, M; Quivy, A; Ravaud, A; Roca, S	1
Avril, N; Bomanji, J; Chowdhury, S; Dickson, J; Ell, P; Kayani, I; Lim, L; Nathan, P; Powles, T; Reynolds, A; Rockall, A; Sahdev, A; Shamash, J; Sharpe, K; Wilson, P	1
Busch, J; Grünwald, V; Hinz, S; Kempkensteffen, C; Magheli, A; Miller, K; Seidel, C; Weikert, S; Weinkauf, L; Wolff, I	1
Atkinson, B; Choueiri, TK; Chowdhury, S; Matrana, MR; Tannir, NM; Tsang, C	1
Bex, A; Blank, C; Haanen, J; Horenblas, S; Meinhardt, W; van Tinteren, H	1
Chen, I; Chow Maneval, E; George, DJ; Harmon, CS; Hutson, TE; Kozloff, M; Liu, G; Logothetis, CJ; Mathew, P; Shore, ND; Wang, SL; Wilding, G; Zurita, AJ	1
Atkins, M; Bukowski, R; Choueiri, TK; Dutcher, J; Eisen, T; Elson, P; Escudier, B; Heng, DY; Manola, J; Mazumdar, M; McCormack, JB; Motzer, R; Négrier, S; Royston, P	1
Purmonen, TT	1
Gao, H; Guo, W; Liu, X	1
Barrios, CH; Bello, A; Brown, MP; Fein, L; Hariharan, S; Hernandez-Barajas, D; Lee, SH; Liu, JH; Martell, BA; Mundayat, R; Rha, SY; Wang, Z; Yuan, J	1
Boven, E; Broxterman, HJ; de Haas, RR; Haanen, JB; Koolwijk, P; van den Eertwegh, AJ; van der Veldt, AA; van Hinsbergh, VW; Vroling, L	1
Brion, N; Paule, B	1
Kerbel, RS	1
Caram, MV; Schuetze, SM	1
Fujisawa, M; Harada, K; Kusuda, Y; Miyake, H; Sakai, I	1
Ashley, SW; Grover, S; Raut, CP	1
Chika, N; Kakimoto, M; Kikuchi, A; Koshiishi, H; Nishida, K; Okamura, T; Tokita, H; Yoshimura, T	1
Ahn, H; Ahn, JH; Cho, YM; Hong, JH; Kim, CS; Kim, TM; Lee, DH; Lee, JL; Lee, SH; Lim, HY; Park, SH; Song, C	1
Ahn, H; Ahn, JH; Ahn, S; Ahn, Y; Hong, JH; Kim, CS; Kim, TW; Lee, JL; Park, I; Park, K; Park, S; Song, C	1
Bushmakin, AG; Cappelleri, JC; Cella, D; Charbonneau, C; Michaelson, MD; Motzer, RJ	1
Brentani, RR; Cooke, VG; Damascena, A; Duncan, MB; Kalluri, R; Keskin, D; Khan, Z; LeBleu, VS; Maeda, G; O'Connell, JT; Rocha, RM; Sugimoto, H; Teng, Y; Vong, S; Xie, L	1
Christensen, JG; Lappin, PB; Lee, JH; Shojaei, F; Simmons, BH	1
Ankersmit, HJ; de Martino, M; Haitel, A; Hoetzenecker, K; Klatte, T; Roth, GA; Waldert, M	1
Aparicio, L; Fernández, O; Grande, E; Lázaro, M; León, L; Vázquez, S	1
Buonerba, C; De Placido, S; Di Lorenzo, G	1
Aste, MG; Buti, S; Conte, PF; Cosmai, L; Del Giovane, C; Di Lorenzo, G; Grosso, F; Iacovelli, R; Invernizzi, R; Lucia Manenti, A; Masini, C; Moscetti, L; Onofri, A; Ortega, C; Pagano, M; Porta, C; Procopio, G; Sabbatini, R	1
Beenakker, JW; Cui, C; Danen, EH; Ghotra, VP; He, S; Lamers, GE; Meijer, AH; Snaar-Jagalska, BE; Spaink, HP	1
Ping, SY; Wu, CL; Yu, CP; Yu, DS	1
Boni, G; Ferdeghini, M; Mariani, G; Monzani, F; Pasqualetti, G; Polini, A; Ricci, S; Tognini, S	1
Denda, T; Hashigaki, S; Kato, T; Komatsu, Y; Lechuga, MJ; Miyata, Y; Mizutani, N; Muro, K; Nagase, M; Nishina, T; Satoh, T; Tsuji, A; Tsuji, Y; Yoshida, M	1
Cowell, JK; Ghoshal, P; Lesoon, LA; Teng, Y	1
Chung, AS; Ferrara, N; Finkle, D; Komuves, L; Kowanetz, M; Ngu, H; Peale, F; Wu, X; Zhuang, G	1
Barck, KH; Cao, TC; Carano, RA; Cheng, JH; Couto, SS; Eastham-Anderson, J; Ferrara, N; Foreman, O; Forrest, WF; Hamilton, P; Ho, CC; Johnson, L; Jubb, AM; Kasman, I; Lima, A; Long, JE; McNutt, A; Molina, R; Nannini, MA; Reslan, HB; Singh, M	1
Butrynski, JE; Choy, E; Corless, CL; Demetri, GD; Fletcher, JA; George, S; Heinrich, MC; Manola, JB; Morgan, JA; Solomon, SM; Tap, WD; Van den Abbeele, AD; von Mehren, M; Wagner, AJ; Wang, Q; Yap, JT; Zhu, M	1
Daimon, M; Kaino, W; Kameda, W; Karasawa, S; Kato, T; Oizumi, T; Susa, S; Takase, K; Tomita, Y; Wada, K	1
Castellano, D; De Velasco, G; Ravaud, A; Schmidinger, M; Vazquez, F	1
Bamias, A; Dimitriadis, G; Dimopoulos, MA; Economopoulos, T; Migkou, M; Nicolatou-Galitis, O; Pectasides, D; Psyrri, A; Raber-Durlacher, JE	1
Abrahamova, J; Bortlicek, Z; Buchler, T; Dusek, L; Melichar, B; Pavlik, T; Poprach, A; Puzanov, I; Vyzula, R	1
Drudi, F; Giuliani, J	1
Blumenschein, GR; Chao, RC; Ciuleanu, T; Groen, HJ; Juhasz, E; Robert, F; Ruiz-Garcia, A; Tye, L; Usari, T	1
Hanovich, E; Hercbergs, AH; Kovel, S; Sella, A	1
Cesaretti, JA; Chen, SH; Forsythe, K; Galsky, M; Genden, EM; Kao, J; Ko, EC; Lau, KH; Ozao-Choy, J; Packer, SH; Schwartz, M; Stock, RG; Sung, MW; Tong, CC	1
Boleti, E; Chowdury, S; Crabb, SJ; Jones, R; Nathan, P; Powles, T; Protheroe, A; Rashid, S; Sarwar, N; Shamash, J; Stockdale, A; Wilson, P	1
Braunfeld, J; Brekken, RA; Burrows, FJ; Carbon, JG; Kirane, A; Ostapoff, K; Schwarz, RE; Toombs, JE; Zaknoen, S	1
Donohue, JH; Nagorney, DM; Okuno, SH; Que, FG; Zaydfudim, V	1
Bird, D; Erler, JT; Foo, S; Foster, J; Frentzas, S; Gourlaouen, M; Mather, SJ; Pili, R; Powles, T; Preece, N; Reynolds, AR; Robertson, D; Sharpe, K; Soffe, J; Springer, CJ; van Weverwijk, A; Welti, JC	1
Kaklamani, V; Raffin, M; Reddy, S	1
Goto, Y; Hirata, T; Ikeda, Y; Nokihara, H; Tamura, T; Tanioka, M; Yamada, K; Yamada, Y; Yamamoto, N	1
Bai, W; He, AR; Hwang, J; Marshall, J; Mikhail, S; Navarro, R; Pishvaian, M; Shivapurkar, N; Wellstein, A	1
Carley, W; DePrimo, SE; Harmon, CS; Huang, X; Kern, KA; Keyvanjah, K	1
Dreyer, C; Faivre, S; Raymond, E	1
Krzemieniecki, K; Sowa-Staszczak, A; Zygulska, AL	1
Aldrighetti, D; Amadori, D; Bouko, Y; Canon, JL; Cardoso, F; Dirix, L; Giorgetti, C; Kern, KA; Machiels, JP; Usari, T; Verkh, L	1
Bodnar, L; Duchnowska, R; Miciuk, B; Szczylik, C; Waśniewski, L	1
Chan, K; Laudadio, M; Mahipal, A; Mastrangelo, MJ; Sato, T; Tijani, L	1
Karakiewicz, PI; Sun, M; Trinh, QD	1
Berkers, J; Beuselinck, B; Body, JJ; Debruyne, P; Dumez, H; Elaidi, R; Karadimou, A; Lerut, E; Paridaens, R; Rogiers, A; Schöffski, P; Van Cann, T; Van Poppel, H; Willems, L; Wolter, P	1
Blanc, E; Escudier, B; Ferlay, C; Genin, C; Gigante, M; Li, G; Negrier, S; Paul, S; Perol, D; Tostain, J; Zhao, A	1
Borker, R; Fonseca, E; Hess, G	1
Chao, RC; Hara, K; Hashigaki, S; Igarashi, H; Imamura, M; Ito, T; Kimura, N; Kondo, S; Mizuno, N; Morizane, C; Murakami, M; Nishida, T; Ohki, E; Okusaka, T; Sawaki, A; Yamao, K	1
Downey, FP; McDermott, RS; Teo, M	1
Ahn, H; Ahn, JH; Ahn, Y; Choi, HJ; Hong, JH; Jeong, IG; Kim, CS; Lee, JL; Park, I; Park, K; Park, S; Song, C	1
Vogelzang, NJ	2
Bondarenko, I; Carrato, A; Christensen, JG; De la Cruz, JA; Jonker, DJ; Korytowsky, B; Lechuga, MJ; Lim, R; Lin, X; Roman, L; Shparyk, Y; Staszewska-Skurczynska, M; Sun, Y; Swieboda-Sadlej, A; Tursi, JM; Van Cutsem, E; Williams, JA	1
Gorelik, E; Huang, X; Laird, AD; Watkins, S; Wolf, SF; Wong, MK; Yi, H	1
Baker, CH; Dinney, CP; Fidler, IJ; Kedar, D; Killion, JJ	1
Carranza, DC; Chen, IY; Collisson, EA; Kolodney, MS	1
Chu, E	1
Alileche, A	1
Fidler, IJ; Karashima, T; Killion, JJ; Kim, SJ; Shepherd, DL; Uehara, H	1
Cherrington, JM; DePrimo, SE; Khatry, DB; Manning, WC; Nicholas, SL; O'Farrell, AM; Smolich, BD; Wong, LM	1
Collisson, EA; De, A; Gambhir, SS; Kleer, C; Kolodney, MS; Merajver, SD; Wu, M	1
Cherrington, JM; Lee, LB; London, CA; Pryer, NK; Sukbuntherng, J; Yu, X; Zadovaskaya, R	1
Gajewski, TF; Karczmar, G; Medved, M; Peterson, AC; Stadler, WM; Swiger, S	1
Bae, JH; Chung, BS; Ju, DS; Kang, CD; Kim, DW; Kim, MJ; Kim, SH; Kwon, JK; Um, JH	1
Kohno, T; Konno, R; Machida, S; Mizuno, I; Ohwada, M; Saga, Y; Suzuki, M; Takayama, T; Takei, Y	1
Fu, A; Geng, L; Hallahan, DE; Osusky, KL; Shyr, Y; Ye, F	1
Baum, CM; Bello, CL; DePrimo, SE; Figlin, RA; George, DJ; Ginsberg, MS; Hudes, GR; Kim, ST; Li, JZ; Michaelson, MD; Motzer, RJ; Redman, BG; Rini, BI; Theuer, CP; Wilding, G	1
Chaganti, RS; Motzer, RJ; Patel, PH	1
Berghaus, A; Dellian, M; Eichhorn, ME; Jonczyk, A; Strieth, S; Sutter, A	1
Rini, BI	1
Berlin, JD; Cropp, GF; Donnelly, E; Fleischer, AC; Hande, KR; Hannah, AL; Lockhart, AC; Rothenberg, ML; Schaaf, LJ; Schumaker, RD	1
Beeram, M; Berg, K; de Bono, JS; Eckhart, SG; Forero, L; Hammond, LA; Izbicka, E; Mita, AC; Mita, MM; Patnaik, A; Rowinsky, EK; Simmons, P; Takimoto, C; Tolcher, AW; Weiss, GR	1
Mancuso, A; Sternberg, CN	1
Blanke, CD; Schnadig, ID	1
Burstein, HJ; Rugo, HS; Sledge, GW	1
Chen, I; Kim, ST; Rini, BI; Rosenberg, JE; Shaw, V	1
Cuneo, KC; Fu, A; Geng, L; Osusky, KL	1
García-Echeverría, C; Hofmann, F; Landuzzi, L; Lollini, PL; Manara, MC; Nanni, C; Nanni, P; Nicoletti, G; Picci, P; Scotlandi, K; Zambelli, D	1
Figlin, RA	1
Heldin, CH; Ostman, A	1
Maki, RG	1
de Lima Lopes, G; Rocha Lima, CM	1
Boven, E; van den Eertwegh, AJ; van der Veldt, AA	1
Billemont, B; Izzedine, H; Rixe, O	1
Grosicka, A; Grosicki, S; Hołowiecki, J	1
Chouhan, JD; Grabinski, JL; Lai, PH; Oramasionwu, CU; Zamarripa, DE	1
Albers, P; Bergmann, L; Geschwend, JE; Jäger, E; Jakse, G; Marschner, N; Miller, K	1
Bellido, L; Cruz, JJ; Martín, G	1
Hayes, DF; Miller, K; Sledge, G	1
Alba, E; Medina, MA; Quesada, AR	1
Polyzos, A	1
Gratama, JW; Kraan, J; Sleijfer, S; Strijbos, MH	1
Bukowski, RM; Garcia, J; Heng, DY; Rini, BI; Wood, L	1
de Mulder, PH; Gietema, JA; Groenewegen, G; Haanen, JB; Jansen, RL; Kruit, WH; Mulders, PF; Osanto, S; Richel, DJ; Sleijfer, S; van den Eertwegh, AJ; Voest, EE	1
Hioki, K; Kameshita, I; Mohri, T; Suzuki, S; Takatani, S; Tokunaga, R	1
Nagy, A; Plonowski, A; Schally, AV; Sun, B; Szepeshazi, K	1
Angelov, L; Guha, A; McMahon, G; Roncari, L; Salhia, B	1
Ellis, LM; Liu, W; Shaheen, RM; Takahashi, Y	1
Benali, N; Buscail, L; Calise, D; Cordelier, P; Esteve, JP; Nagy, A; Pages, P; Pour, PM; Rochaix, P; Schally, AV; Susini, C; Vaysse, N	1
Baker, CH; Buchdunger, E; Cohen, P; Fidler, IJ; Killion, JJ; Solorzano, CC; Traxler, P; Tsan, R	1
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Braune, M; Freyer, W; Lewald, T; Naether, D; Nowak, C; Roeder, B	1
Schein, PS	1

Reviews

57 review(s) available for pyrroles and Metastase

Article	Year
Experience with Sunitinib in metastatic renal cell carcinoma (mRCC) patients: pooled analysis from 3 Spanish observational prospective studies. Expert opinion on drug safety, 2018, Volume: 17, Issue:6 Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Humans; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Pyrroles; Randomized Controlled Trials as Topic; Spain; Sunitinib; Survival Rate; Treatment Outcome	2018
Evolving Treatment Paradigm in Metastatic Renal Cell Carcinoma. American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting, 2017, Volume: 37 Topics: Carcinoma, Renal Cell; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Indoles; Neoplasm Metastasis; Neoplasm Proteins; Neovascularization, Pathologic; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyrroles; Quinolines; Sorafenib; Sunitinib; Von Hippel-Lindau Tumor Suppressor Protein	2017
Side-effects associated with targeted therapies in renal cell carcinoma. Current opinion in supportive and palliative care, 2013, Volume: 7, Issue:3 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Dose-Response Relationship, Drug; Everolimus; Humans; Indazoles; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Receptors, Vascular Endothelial Growth Factor; Sirolimus; Sulfonamides; Sunitinib	2013
Preclinical recapitulation of antiangiogenic drug clinical efficacies using models of early or late stage breast cancer metastatis. Breast (Edinburgh, Scotland), 2013, Volume: 22 Suppl 2 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Clinical Trials, Phase III as Topic; Disease Models, Animal; Female; Heterografts; Humans; Indoles; Mice; Mice, Transgenic; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Staging; Neoplasm Transplantation; Pyrroles; Species Specificity; Sunitinib; Survival Analysis; Treatment Outcome	2013
[Medical treatment of renal cell carcinoma]. Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 2013, Volume: 23, Issue:15 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Carcinoma, Renal Cell; Everolimus; Humans; Immunotherapy; Indoles; Interferon alpha-2; Interferon-alpha; Interleukin-2; Kidney Neoplasms; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Sirolimus; Societies, Medical; Sorafenib; Sunitinib; Vascular Endothelial Growth Factor A	2013
Tyrosine kinase inhibitors in the treatment of unresectable or metastatic gastrointestinal stromal tumors. Expert opinion on pharmacotherapy, 2014, Volume: 15, Issue:14 Topics: Antineoplastic Combined Chemotherapy Protocols; Benzamides; Drug Resistance, Neoplasm; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Neoplasm Metastasis; Phenylurea Compounds; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-kit; Pyridines; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sunitinib	2014
Comparative effectiveness of approved first-line anti-angiogenic and molecularly targeted therapeutic agents in the treatment of good and intermediate risk metastatic clear cell renal cell carcinoma. BMC cancer, 2014, Aug-15, Volume: 14 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoma, Renal Cell; Humans; Indazoles; Indoles; Interferons; Kidney Neoplasms; Molecular Targeted Therapy; Neoplasm Metastasis; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Sulfonamides; Sunitinib; Survival Analysis	2014
Alternative dosing schedules for sunitinib as a treatment of patients with metastatic renal cell carcinoma. Critical reviews in oncology/hematology, 2014, Volume: 92, Issue:3 Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Carcinoma, Renal Cell; Drug Administration Schedule; Humans; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Pyrroles; Sunitinib; Treatment Outcome	2014
Kidney cancer in 2014: Key advances promise progress for kidney cancer patients. Nature reviews. Urology, 2015, Volume: 12, Issue:2 Topics: Angiogenesis Inhibitors; Carcinogenesis; Carcinoma, Renal Cell; Disease Progression; Humans; Indazoles; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Nephrectomy; Nephrons; Organ Sparing Treatments; Pyrimidines; Pyrroles; Sulfonamides; Sunitinib	2015
Recent aspects of sunitinib therapy in patients with metastatic clear-cell renal cell carcinoma: a systematic review of the literature. Current urology reports, 2015, Volume: 16, Issue:2 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Humans; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Pyrroles; Sunitinib; Treatment Outcome	2015
Diagnostic and therapeutic implications of the vascular endothelial growth factor family in cancer. Asian Pacific journal of cancer prevention : APJCP, 2015, Volume: 16, Issue:5 Topics: Angiogenesis Inhibitors; Bevacizumab; Humans; Indoles; Neoplasm Metastasis; Neoplasm Staging; Neoplasms; Neovascularization, Pathologic; Prognosis; Protein Kinase Inhibitors; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Vascular Endothelial Growth Factors	2015
Real-World Effectiveness of Everolimus Subsequent to Different First Targeted Therapies for the Treatment of Metastatic Renal Cell Carcinoma: Synthesis of Retrospective Chart Reviews. Clinical genitourinary cancer, 2016, Volume: 14, Issue:2 Topics: Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Everolimus; Female; Humans; Indazoles; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Proportional Hazards Models; Pyrimidines; Pyrroles; Retrospective Studies; Sorafenib; Sulfonamides; Sunitinib; Survival Analysis; Treatment Outcome	2016
A decade of pharmacogenomics research on tyrosine kinase inhibitors in metastatic renal cell cancer: a systematic review. Expert review of molecular diagnostics, 2016, Volume: 16, Issue:5 Topics: Antineoplastic Agents; Biomarkers, Pharmacological; Carcinoma, Renal Cell; Gene Expression; Humans; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Niacinamide; Pharmacogenetics; Phenylurea Compounds; Polymorphism, Single Nucleotide; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrroles; Sorafenib; Sunitinib; Treatment Outcome	2016
First-line therapy for treatment-naive patients with advanced/metastatic renal cell carcinoma: a systematic review of published randomized controlled trials. Anti-cancer drugs, 2016, Volume: 27, Issue:5 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Axitinib; Bevacizumab; Carcinoma, Renal Cell; Humans; Imidazoles; Indazoles; Indoles; Interferon-alpha; Kidney Neoplasms; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Pyrimidines; Pyrroles; Quality of Life; Quinazolines; Quinolines; Randomized Controlled Trials as Topic; Sirolimus; Sorafenib; Sulfonamides; Sunitinib	2016
Meta-analysis on the association of VEGFR1 genetic variants with sunitinib outcome in metastatic renal cell carcinoma patients. Oncotarget, 2017, Jan-03, Volume: 8, Issue:1 Topics: Alleles; Antineoplastic Agents; Carcinoma, Renal Cell; Gene Frequency; Genetic Variation; Genotype; Humans; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Polymorphism, Single Nucleotide; Prognosis; Proportional Hazards Models; Pyrroles; Sunitinib; Treatment Outcome; Vascular Endothelial Growth Factor Receptor-1	2017
How clinical practice is changing the rules: the sunitinib 2/1 schedule in metastatic renal cell carcinoma. Expert review of anticancer therapy, 2017, Volume: 17, Issue:3 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Pyrroles; Research Design; Sunitinib	2017
Effects and Side Effects of Using Sorafenib and Sunitinib in the Treatment of Metastatic Renal Cell Carcinoma. International journal of molecular sciences, 2017, Feb-21, Volume: 18, Issue:2 Topics: Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Disease Management; Drug Resistance, Neoplasm; Humans; Indoles; Molecular Targeted Therapy; Neoplasm Metastasis; Neoplasm Staging; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyrroles; Sorafenib; Sunitinib; Treatment Outcome	2017
An update on the medical therapy of advanced metastatic renal cell carcinoma. Scandinavian journal of urology and nephrology, 2008, Volume: 42, Issue:6 Topics: Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Neoplasm Staging; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrroles; raf Kinases; Severity of Illness Index; Sirolimus; Sorafenib; Sunitinib; Treatment Outcome	2008
Exploring the role of novel agents in the treatment of renal cell carcinoma. Cancer treatment reviews, 2008, Volume: 34, Issue:8 Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Bevacizumab; Carcinoma, Renal Cell; Chemotherapy, Adjuvant; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Drug Delivery Systems; Female; Humans; Indoles; Kidney Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Nephrectomy; Niacinamide; Phenylurea Compounds; Prognosis; Pyridines; Pyrroles; Sirolimus; Sorafenib; Sunitinib; Survival Analysis; Treatment Outcome	2008
Pre-surgical targeted molecular therapy in renal cell carcinoma. BJU international, 2009, Volume: 103, Issue:2 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Clinical Trials, Phase II as Topic; Combined Modality Therapy; Humans; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Nephrectomy; Prognosis; Pyrroles; Randomized Controlled Trials as Topic; Sunitinib	2009
Cytoreductive nephrectomy in metastatic clear-cell renal cell carcinoma: perspectives in the tyrosine kinase inhibitor era. The oncologist, 2009, Volume: 14, Issue:1 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Clinical Trials, Phase III as Topic; Humans; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Nephrectomy; Protein Kinase Inhibitors; Pyrroles; Sunitinib	2009
Targeted therapies in metastatic renal cancer in 2009. BJU international, 2009, Volume: 103, Issue:10 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Axitinib; Benzenesulfonates; Bevacizumab; Carcinoma, Renal Cell; Clinical Trials as Topic; Everolimus; Humans; Imidazoles; Indazoles; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Pyridines; Pyrimidines; Pyrroles; Sirolimus; Sorafenib; Sulfonamides; Sunitinib; Vascular Endothelial Growth Factors	2009
Advanced gastrointestinal stromal tumor in Europe: a review of updated treatment recommendations. Expert review of anticancer therapy, 2009, Volume: 9, Issue:6 Topics: Antineoplastic Agents; Benzamides; Disease Progression; DNA Mutational Analysis; Europe; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Neoplasm Metastasis; Piperazines; Practice Guidelines as Topic; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sunitinib	2009
How can second-line therapy for metastatic renal cell carcinoma help to define an overall management strategy? Oncology, 2009, Volume: 77, Issue:2 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bevacizumab; Carcinoma, Renal Cell; Humans; Indoles; Interferon-alpha; Interleukin-2; Kidney Neoplasms; Neoplasm Metastasis; Pyrroles; Sunitinib	2009
Sorafenib reveals efficacy in sequential treatment of metastatic renal cell cancer. Expert review of anticancer therapy, 2009, Volume: 9, Issue:10 Topics: Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Carcinoma, Renal Cell; Clinical Trials as Topic; Drug Delivery Systems; Drug Resistance, Neoplasm; Humans; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Prognosis; Pyridines; Pyrroles; Sorafenib; Sunitinib	2009
Metastatic renal cell carcinoma: current standards of care. Clinical journal of oncology nursing, 2009, Volume: 13 Suppl Topics: Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Combined Modality Therapy; Everolimus; Humans; Indoles; Interleukin-2; Kidney Neoplasms; Neoplasm Metastasis; Nephrectomy; Niacinamide; Oncology Nursing; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrroles; Sirolimus; Sorafenib; Sunitinib	2009
Update on systemic therapies of metastatic renal cell carcinoma. World journal of urology, 2010, Volume: 28, Issue:3 Topics: Algorithms; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzenesulfonates; Bevacizumab; Biopsy, Needle; Carcinoma, Renal Cell; Clinical Trials, Phase III as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Delivery Systems; Everolimus; Female; Follow-Up Studies; Humans; Immunohistochemistry; Indoles; Interferon-alpha; Kidney Neoplasms; Male; Maximum Tolerated Dose; Neoplasm Metastasis; Neoplasm Staging; Niacinamide; Phenylurea Compounds; Pyridines; Pyrroles; Risk Assessment; Sirolimus; Sorafenib; Sunitinib; Survival Analysis	2010
Sunitinib for the management of advanced renal cell carcinoma. Expert review of anticancer therapy, 2010, Volume: 10, Issue:3 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Clinical Trials, Phase III as Topic; Disease-Free Survival; Drug Delivery Systems; Humans; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Practice Guidelines as Topic; Pyrroles; Sunitinib	2010
New perspectives: role of sunitinib in breast cancer. La Clinica terapeutica, 2010, Volume: 161, Issue:5 Topics: Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Indoles; Neoplasm Metastasis; Pyrroles; Sunitinib	2010
Cost effectiveness of tyrosine kinase inhibitor therapy in metastatic gastrointestinal stromal tumors. Journal of medical economics, 2010, Volume: 13, Issue:4 Topics: Antineoplastic Agents; Benzamides; Cost-Benefit Analysis; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Models, Economic; Neoplasm Metastasis; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Sunitinib	2010
Metastatic gastrointestinal stromal tumors. Cancer chemotherapy and pharmacology, 2011, Volume: 67 Suppl 1 Topics: Antineoplastic Agents; Gastrointestinal Stromal Tumors; Humans; Indoles; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prognosis; Proto-Oncogene Proteins c-kit; Pyrroles; Salvage Therapy; Sunitinib	2011
Sunitinib and other targeted therapies for renal cell carcinoma. British journal of cancer, 2011, Mar-01, Volume: 104, Issue:5 Topics: Biomarkers, Tumor; Carcinoma, Renal Cell; Drug Resistance, Neoplasm; Drug Therapy, Combination; Humans; Indoles; Kidney Neoplasms; Molecular Targeted Therapy; Neoplasm Metastasis; Prognosis; Pyrroles; Randomized Controlled Trials as Topic; Sunitinib; Vascular Endothelial Growth Factor A	2011
Exposure-response relationships in patients with metastatic renal cell carcinoma receiving sunitinib: maintaining optimum efficacy in clinical practice. Anti-cancer drugs, 2011, Volume: 22, Issue:5 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Clinical Trials as Topic; Humans; Indoles; Kidney Neoplasms; Meta-Analysis as Topic; Neoplasm Metastasis; Pyrroles; Sunitinib	2011
[Treatment of metastatic renal cell carcinoma]. Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 2011, Volume: 21, Issue:4 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzenesulfonates; Bevacizumab; Carcinoma, Renal Cell; Humans; Immunotherapy; Indazoles; Indoles; Interferons; Interleukin-2; Kidney Neoplasms; Neoplasm Metastasis; Nephrectomy; Niacinamide; Phenylurea Compounds; Pyridines; Pyrimidines; Pyrroles; Sirolimus; Sorafenib; Sulfonamides; Sunitinib	2011
Multikinase inhibitors in metastatic renal cell carcinoma: indirect comparison meta-analysis. Clinical therapeutics, 2011, Volume: 33, Issue:6 Topics: Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Humans; Indazoles; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Pyrroles; Sorafenib; Sulfonamides; Sunitinib	2011
Systemic therapy for metastatic non-clear-cell renal cell carcinoma: recent progress and future directions. Hematology/oncology clinics of North America, 2011, Volume: 25, Issue:4 Topics: Benzenesulfonates; Carcinoma, Renal Cell; Clinical Trials as Topic; Humans; Indazoles; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Pyrroles; Sorafenib; Sulfonamides; Sunitinib; Treatment Outcome	2011
Cost-effectiveness of sunitinib in metastatic renal cell carcinoma. Expert review of pharmacoeconomics & outcomes research, 2011, Volume: 11, Issue:4 Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Carcinoma, Renal Cell; Cost-Benefit Analysis; Drug Delivery Systems; Humans; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Pyrroles; Sunitinib; Survival	2011
Reappraising antiangiogenic therapy for breast cancer. Breast (Edinburgh, Scotland), 2011, Volume: 20 Suppl 3 Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Humans; Indoles; Mastectomy; Maximum Tolerated Dose; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Prognosis; Pyrroles; Sunitinib; Survival Analysis; Treatment Outcome; Vascular Endothelial Growth Factor A	2011
Advanced or metastatic gastrointestinal stromal tumors: systemic treatment options. Journal of surgical oncology, 2011, Volume: 104, Issue:8 Topics: Antineoplastic Agents; Benzamides; Drug Resistance, Neoplasm; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Neoplasm Metastasis; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sunitinib	2011
Small intestine gastrointestinal stromal tumors. Current opinion in gastroenterology, 2012, Volume: 28, Issue:2 Topics: Antineoplastic Agents; Benzamides; Chemotherapy, Adjuvant; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Intestinal Neoplasms; Intestine, Small; Neoadjuvant Therapy; Neoplasm Metastasis; Piperazines; Prognosis; Pyrimidines; Pyrroles; Sunitinib	2012
Sunitinib: the first to arrive at first-line metastatic renal cell carcinoma. Advances in therapy, 2012, Volume: 29, Issue:3 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Humans; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Pyrroles; Sunitinib	2012
Therapy management with sunitinib in patients with metastatic renal cell carcinoma: key concepts and the impact of clinical biomarkers. Cancer treatment reviews, 2013, Volume: 39, Issue:3 Topics: Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Renal Cell; Humans; Indoles; Kidney Neoplasms; Molecular Targeted Therapy; Neoplasm Metastasis; Prognosis; Pyrroles; Sunitinib	2013
Hypothyroidism during treatment with tyrosine kinase inhibitors. Endokrynologia Polska, 2012, Volume: 63, Issue:4 Topics: Carcinoma, Renal Cell; Dose-Response Relationship, Drug; Gastrointestinal Neoplasms; Humans; Indoles; Kidney Neoplasms; Liver Neoplasms; Neoplasm Metastasis; Neoplasms; Niacinamide; Phenylurea Compounds; Pyrroles; Sorafenib; Sunitinib; Thyroid Diseases; Thyroid Function Tests; Thyroid Gland; Thyroid Neoplasms	2012
Targeted therapy for metastatic renal cell carcinoma. British journal of cancer, 2006, Mar-13, Volume: 94, Issue:5 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Benzenesulfonates; Bevacizumab; Carcinoma, Renal Cell; Clinical Trials as Topic; Enzyme Inhibitors; Humans; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Protein-Tyrosine Kinases; Pyridines; Pyrroles; Sorafenib; Sunitinib	2006
VEGF-targeted therapy in renal cell carcinoma: active drugs and active choices. Current oncology reports, 2006, Volume: 8, Issue:2 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Axitinib; Benzenesulfonates; Bevacizumab; Carcinoma, Renal Cell; Chemotherapy, Adjuvant; ErbB Receptors; Humans; Imidazoles; Indazoles; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Platelet-Derived Growth Factor; Pyridines; Pyrroles; Sorafenib; Sunitinib; Vascular Endothelial Growth Factor A; Von Hippel-Lindau Tumor Suppressor Protein	2006
New treatment approaches in metastatic renal cell carcinoma. Current opinion in urology, 2006, Volume: 16, Issue:5 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Axitinib; Benzenesulfonates; Bevacizumab; Carcinoma, Renal Cell; Erlotinib Hydrochloride; Humans; Imidazoles; Indazoles; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Pyrroles; Quinazolines; Sirolimus; Sorafenib; Sulfonamides; Sunitinib	2006
Gastrointestinal stromal tumors: imatinib and beyond. Current treatment options in oncology, 2006, Volume: 7, Issue:6 Topics: Antineoplastic Agents; Benzamides; Combined Modality Therapy; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Neoplasm Metastasis; Neoplasm Recurrence, Local; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Sunitinib	2006
The role of angiogenesis inhibition in the treatment of breast cancer. Clinical advances in hematology & oncology : H&O, 2006, Volume: 4, Issue:10 Suppl 2 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Breast Neoplasms; Capecitabine; Clinical Trials, Phase III as Topic; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Indoles; Multicenter Studies as Topic; Neoplasm Metastasis; Neovascularization, Pathologic; Paclitaxel; Pyrroles; Randomized Controlled Trials as Topic; Sunitinib; Survival Rate; Vascular Endothelial Growth Factor A	2006
PDGF receptors as targets in tumor treatment. Advances in cancer research, 2007, Volume: 97 Topics: Animals; Antineoplastic Agents; Benzamides; Clinical Trials, Phase III as Topic; Drug Delivery Systems; Extracellular Fluid; Fibroblasts; Humans; Imatinib Mesylate; Indoles; Mutation; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms; Neovascularization, Pathologic; Piperazines; Platelet-Derived Growth Factor; Pressure; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Sunitinib; Translocation, Genetic	2007
Recent advances in therapy for gastrointestinal stromal tumors. Current oncology reports, 2007, Volume: 9, Issue:3 Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Benzamides; Combined Modality Therapy; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Neoplasm Metastasis; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Sunitinib	2007
[Clinical importance of angiogenesis and angiogenic factors in oncohematology]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 2007, Volume: 60, Issue:1-2 Topics: Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Angiopoietin-1; Angiopoietin-2; Hematologic Neoplasms; Humans; Indoles; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Multiple Myeloma; Myelodysplastic Syndromes; Neoplasm Metastasis; Neovascularization, Pathologic; Oxindoles; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Propionates; Pyrroles; Receptor, TIE-2; Receptors, Vascular Endothelial Growth Factor; Vascular Endothelial Growth Factors	2007
Sunitinib (Sutent): a novel agent for the treatment of metastatic renal cell carcinoma. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2007, Volume: 13, Issue:1 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Cell Proliferation; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Humans; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Neovascularization, Pathologic; Pyrroles; Sunitinib	2007
Angiogenesis as targeted breast cancer therapy. Breast (Edinburgh, Scotland), 2007, Volume: 16 Suppl 2 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bevacizumab; Breast Neoplasms; Female; Humans; Indoles; Neoplasm Metastasis; Neovascularization, Pathologic; Pyrroles; Sunitinib; Vascular Endothelial Growth Factor A	2007
Playing only one instrument may be not enough: limitations and future of the antiangiogenic treatment of cancer. BioEssays : news and reviews in molecular, cellular and developmental biology, 2007, Volume: 29, Issue:11 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Indoles; Lung Neoplasms; Models, Biological; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Niacinamide; Phenylurea Compounds; Pyridines; Pyrroles; Sorafenib; Sunitinib; Vascular Endothelial Growth Factor A	2007
Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma and various other solid tumors. The Journal of steroid biochemistry and molecular biology, 2008, Volume: 108, Issue:3-5 Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Renal Cell; Female; Gastrointestinal Stromal Tumors; Humans; Indoles; Kidney Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neuroendocrine Tumors; Pyrroles; Receptors, Platelet-Derived Growth Factor; Receptors, Vascular Endothelial Growth Factor; Sunitinib	2008
[Angiogenesis inhibitors for the systemic treatment of metastatic renal cell carcinoma: sunitinib, sorafenib, bevacizumab and temsirolimus]. Nederlands tijdschrift voor geneeskunde, 2008, Feb-16, Volume: 152, Issue:7 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Bevacizumab; Carcinoma, Renal Cell; Disease-Free Survival; Humans; Immunotherapy; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Pyridines; Pyrroles; Signal Transduction; Sirolimus; Sorafenib; Sunitinib; Treatment Outcome	2008
Chemotherapeutic management of the hormone-secreting endocrine malignancies. Cancer, 1972, Volume: 30, Issue:6 Topics: Adenoma, Islet Cell; Adrenal Gland Neoplasms; Aminoglutethimide; Aniline Compounds; Antibiotics, Antineoplastic; Antineoplastic Agents; Butanones; Carcinoid Tumor; Diazoxide; Humans; Hypoglycemia; Insulin Antagonists; Kidney Tubules; Metyrapone; Mitotane; Neoplasm Metastasis; Pheochromocytoma; Pyrimidines; Pyrroles; Pyrrolidines; Ribonucleosides; Serotonin Antagonists; Streptozocin	1972

Trials

100 trial(s) available for pyrroles and Metastase

Article	Year
Fulvestrant plus capivasertib versus placebo after relapse or progression on an aromatase inhibitor in metastatic, oestrogen receptor-positive breast cancer (FAKTION): a multicentre, randomised, controlled, phase 2 trial. The Lancet. Oncology, 2020, Volume: 21, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Double-Blind Method; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Fulvestrant; Humans; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prognosis; Pyrimidines; Pyrroles; Receptors, Estrogen; Salvage Therapy; Survival Rate	2020
Pemigatinib for previously treated, locally advanced or metastatic cholangiocarcinoma: a multicentre, open-label, phase 2 study. The Lancet. Oncology, 2020, Volume: 21, Issue:5 Topics: Adult; Aged; Cholangiocarcinoma; Drug-Related Side Effects and Adverse Reactions; Female; Fibroblast Growth Factors; Humans; Male; Middle Aged; Morpholines; Neoplasm Metastasis; Neoplasm Recurrence, Local; Oncogene Proteins, Fusion; Progression-Free Survival; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Receptor, Fibroblast Growth Factor, Type 2; Receptors, Fibroblast Growth Factor	2020
Pan-AKT Inhibitor Capivasertib With Docetaxel and Prednisolone in Metastatic Castration-Resistant Prostate Cancer: A Randomized, Placebo-Controlled Phase II Trial (ProCAID). Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2021, 01-20, Volume: 39, Issue:3 Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Docetaxel; Double-Blind Method; Humans; Male; Middle Aged; Neoplasm Metastasis; Prednisolone; Progression-Free Survival; Prostatic Neoplasms, Castration-Resistant; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Time Factors; United Kingdom	2021
Germline Genetic Biomarkers of Sunitinib Efficacy in Advanced Renal Cell Carcinoma: Results From the RENAL EFFECT Trial. Clinical genitourinary cancer, 2017, Volume: 15, Issue:5 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Female; Genetic Markers; Genotype; Germ-Line Mutation; Humans; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Male; Neoplasm Metastasis; Pharmacogenomic Variants; Pyrroles; Retrospective Studies; Sunitinib; Treatment Outcome	2017
Association of post-treatment hypoalbuminemia and survival in Chinese patients with metastatic renal cell carcinoma. Chinese journal of cancer, 2017, May-18, Volume: 36, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Hypoalbuminemia; Indoles; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Prognosis; Proportional Hazards Models; Protein Kinase Inhibitors; Pyrroles; Sorafenib; Sunitinib; Treatment Outcome	2017
Evaluation of treatment response and resistance in metastatic renal cell cancer (mRCC) using integrated BMC cancer, 2017, 06-02, Volume: 17, Issue:1 Topics: Adult; Aged; Axitinib; Bevacizumab; Carcinoma, Renal Cell; Cell Proliferation; Contrast Media; Female; Fluorodeoxyglucose F18; Humans; Imidazoles; Indazoles; Indoles; London; Male; Middle Aged; Multimodal Imaging; Neoplasm Metastasis; Neoplasms, Second Primary; Positron-Emission Tomography; Pyrimidines; Pyrroles; Sulfonamides; Sunitinib; Treatment Outcome	2017
Famitinib versus placebo in the treatment of refractory metastatic colorectal cancer: a multicenter, randomized, double-blinded, placebo-controlled, phase II clinical trial. Chinese journal of cancer, 2017, 12-22, Volume: 36, Issue:1 Topics: Administration, Oral; Adult; Aged; Colorectal Neoplasms; Double-Blind Method; Drug Administration Schedule; Female; Humans; Indoles; Male; Neoplasm Metastasis; Protein Kinase Inhibitors; Pyrroles; Survival Analysis; Treatment Outcome	2017
BEECH: a dose-finding run-in followed by a randomised phase II study assessing the efficacy of AKT inhibitor capivasertib (AZD5363) combined with paclitaxel in patients with estrogen receptor-positive advanced or metastatic breast cancer, and in a PIK3CA Annals of oncology : official journal of the European Society for Medical Oncology, 2019, 05-01, Volume: 30, Issue:5 Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Double-Blind Method; Female; Humans; Mutation; Neoplasm Metastasis; Neoplasm Recurrence, Local; Paclitaxel; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Receptors, Estrogen; Survival Rate	2019
A phase I trial to determine the safety, pharmacokinetics, and pharmacodynamics of intercalated BMS-690514 with paclitaxel/carboplatin (PC) in advanced or metastatic solid malignancies. Cancer chemotherapy and pharmacology, 2013, Volume: 71, Issue:5 Topics: Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carboplatin; Dose-Response Relationship, Drug; Female; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Metastasis; Neoplasms; Paclitaxel; Piperidines; Pyrroles; Treatment Outcome; Triazines	2013
Phase I-IIa study of BMS-690514, an EGFR, HER-2 and -4 and VEGFR-1 to -3 oral tyrosine kinase inhibitor, in patients with advanced or metastatic solid tumours. European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:8 Topics: Administration, Oral; Adult; Aged; Area Under Curve; Carcinoma, Non-Small-Cell Lung; Diarrhea; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Exanthema; Female; Humans; Lung Neoplasms; Male; Metabolic Clearance Rate; Middle Aged; Neoplasm Metastasis; Neoplasms; Piperidines; Protein Kinase Inhibitors; Pyrroles; Quinazolines; Receptor, ErbB-2; Treatment Outcome; Triazines; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-3	2013
A prospective evaluation of VEGF-targeted treatment cessation in metastatic clear cell renal cancer. Annals of oncology : official journal of the European Society for Medical Oncology, 2013, Volume: 24, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Carcinoma, Renal Cell; Disease-Free Survival; Drug Administration Schedule; Female; Fluorodeoxyglucose F18; Humans; Indazoles; Indoles; Kidney Neoplasms; Male; Middle Aged; Molecular Targeted Therapy; Neoplasm Metastasis; Nephrectomy; Positron-Emission Tomography; Prospective Studies; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Radiopharmaceuticals; Sulfonamides; Sunitinib; Treatment Outcome; Vascular Endothelial Growth Factor A; Withholding Treatment	2013
Concurrent sunitinib and stereotactic body radiotherapy for patients with oligometastases: final report of a prospective clinical trial. Targeted oncology, 2014, Volume: 9, Issue:2 Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Chemoradiotherapy; Combined Modality Therapy; Female; Humans; Indoles; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Radiosurgery; Sunitinib	2014
Phase III trial of sunitinib in combination with capecitabine versus capecitabine monotherapy for the treatment of patients with pretreated metastatic breast cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Aug-10, Volume: 31, Issue:23 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Indoles; Middle Aged; Neoplasm Metastasis; Prospective Studies; Pyrroles; Sunitinib; Young Adult	2013
Maintenance sunitinib or observation in metastatic pancreatic adenocarcinoma: a phase II randomised trial. European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:17 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Female; Humans; Indoles; Maintenance Chemotherapy; Male; Middle Aged; Neoplasm Metastasis; Pancreatic Neoplasms; Pyrroles; Sunitinib; Survival Analysis	2013
Randomized phase II study of sunitinib versus standard of care for patients with previously treated advanced triple-negative breast cancer. Breast (Edinburgh, Scotland), 2013, Volume: 22, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Agents; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Disease-Free Survival; Docetaxel; Fatigue; Female; Fluorouracil; Gemcitabine; Hand-Foot Syndrome; Humans; Indoles; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neutropenia; Paclitaxel; Pyrroles; Sunitinib; Survival Rate; Taxoids; Thrombocytopenia; Triple Negative Breast Neoplasms	2013
Pharmacogenetic determinants associated with sunitinib-induced toxicity and ethnic difference in Korean metastatic renal cell carcinoma patients. Cancer chemotherapy and pharmacology, 2013, Volume: 72, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Asian People; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Carcinoma, Renal Cell; Female; Genotype; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Proteins; Pharmacogenetics; Polymorphism, Single Nucleotide; Prospective Studies; Pyrroles; Republic of Korea; Sunitinib	2013
Brostallicin versus doxorubicin as first-line chemotherapy in patients with advanced or metastatic soft tissue sarcoma: an European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group randomised phase II and pharmacogeneti European journal of cancer (Oxford, England : 1990), 2014, Volume: 50, Issue:2 Topics: Adult; Antibiotics, Antineoplastic; Bone Neoplasms; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Europe; Gene Frequency; Genotype; Glutathione Transferase; Guanidines; Humans; Isoenzymes; Kaplan-Meier Estimate; Middle Aged; Neoplasm Metastasis; Pharmacogenetics; Polymorphism, Genetic; Pyrroles; Sarcoma; Treatment Outcome	2014
Outcomes in patients with metastatic renal cell cancer treated with individualized sunitinib therapy: correlation with dynamic microbubble ultrasound data and review of the literature. Urologic oncology, 2014, Volume: 32, Issue:4 Topics: Angiogenesis Inhibitors; Carcinoma, Papillary; Carcinoma, Renal Cell; Female; Follow-Up Studies; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Prognosis; Pyrroles; Retrospective Studies; Review Literature as Topic; Sunitinib; Survival Rate	2014
Randomized, placebo-controlled, phase III trial of sunitinib plus prednisone versus prednisone alone in progressive, metastatic, castration-resistant prostate cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Jan-10, Volume: 32, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Anemia; Antineoplastic Combined Chemotherapy Protocols; Asthenia; Disease Progression; Disease-Free Survival; Docetaxel; Double-Blind Method; Drug Administration Schedule; Drug Resistance, Neoplasm; Fatigue; Humans; Indoles; Kaplan-Meier Estimate; Lymphopenia; Male; Middle Aged; Neoplasm Metastasis; Orchiectomy; Prednisone; Prostatic Neoplasms; Pyrroles; Sunitinib; Taxoids; Treatment Outcome	2014
Diffusion-weighted and multiphase contrast-enhanced MRI as surrogate markers of response to neoadjuvant sunitinib in metastatic renal cell carcinoma. British journal of cancer, 2014, Feb-04, Volume: 110, Issue:3 Topics: Adult; Aged; Biomarkers; Carcinoma, Renal Cell; Diffusion Magnetic Resonance Imaging; Female; Humans; Indoles; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Metastasis; Prognosis; Pyrroles; Radiography; Sunitinib; Treatment Outcome	2014
Sunitinib in combination with trastuzumab for the treatment of advanced breast cancer: activity and safety results from a phase II study. BMC cancer, 2014, Mar-07, Volume: 14 Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Indoles; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Pyrroles; Sunitinib; Trastuzumab; Treatment Outcome	2014
Characterizing fatigue associated with sunitinib and its impact on health-related quality of life in patients with metastatic renal cell carcinoma. Cancer, 2014, Jun-15, Volume: 120, Issue:12 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Drug Administration Schedule; Fatigue; Female; Humans; Indoles; Interferon-alpha; Kidney Neoplasms; Male; Models, Statistical; Neoplasm Metastasis; Pyrroles; Quality of Life; Retrospective Studies; Sunitinib; Surveys and Questionnaires; Treatment Outcome	2014
Impairment of cognitive functioning during Sunitinib or Sorafenib treatment in cancer patients: a cross sectional study. BMC cancer, 2014, Mar-24, Volume: 14 Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Renal Cell; Cognition; Cognition Disorders; Cross-Sectional Studies; Female; Humans; Indoles; Kidney Neoplasms; Male; Memory; Middle Aged; Neoplasm Metastasis; Neuropsychological Tests; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyrroles; Sorafenib; Sunitinib	2014
Hypothyroidism as a potential biomarker of efficacy of famitinib, a novel VEGFR-2 inhibitor in metastatic breast cancer. Cancer chemotherapy and pharmacology, 2014, Volume: 74, Issue:2 Topics: Adolescent; Adult; Aged; Biomarkers, Tumor; Breast Neoplasms; Female; Follow-Up Studies; Humans; Hypothyroidism; Indoles; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Prognosis; Pyrroles; Survival Rate; Thyrotropin; Vascular Endothelial Growth Factor Receptor-2; Young Adult	2014
Randomized phase II study of carboplatin and etoposide with or without obatoclax mesylate in extensive-stage small cell lung cancer. Lung cancer (Amsterdam, Netherlands), 2014, Volume: 85, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Comorbidity; Etoposide; Female; Humans; Indoles; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Pyrroles; Small Cell Lung Carcinoma; Treatment Outcome	2014
Phase II randomized trial comparing sequential first-line everolimus and second-line sunitinib versus first-line sunitinib and second-line everolimus in patients with metastatic renal cell carcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Sep-01, Volume: 32, Issue:25 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Cross-Over Studies; Disease-Free Survival; Drug Administration Schedule; Everolimus; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Sirolimus; Sunitinib; Treatment Outcome; Young Adult	2014
Phase I study of sunitinib in combination with gemcitabine and capecitabine for first-line treatment of metastatic or unresectable renal cell carcinoma. The oncologist, 2014, Volume: 19, Issue:9 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoma, Renal Cell; Deoxycytidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Fluorouracil; Gemcitabine; Humans; Indoles; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Sunitinib; Treatment Outcome	2014
Sunitinib still fi rst-line therapy for metastatic renal cancer. The Lancet. Oncology, 2014, Volume: 15, Issue:10 Topics: Carcinoma, Renal Cell; Disease-Free Survival; Everolimus; Female; Humans; Indoles; Kidney Neoplasms; Male; Neoplasm Metastasis; Prognosis; Pyrroles; Risk Assessment; Sirolimus; Sunitinib; Survival Analysis; Time Factors; Treatment Outcome	2014
Phase I trial of sunitinib and temsirolimus in metastatic renal cell carcinoma. Clinical genitourinary cancer, 2015, Volume: 13, Issue:3 Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bayes Theorem; Carcinoma, Renal Cell; Drug Administration Schedule; Female; Humans; Indoles; Kidney Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Metastasis; Pyrroles; Sirolimus; Sunitinib; Treatment Outcome; Young Adult	2015
Efficacy and tolerability of a low-dose, 2-week administration of sunitinib followed by a week rest (2/1 schedule) for metastatic renal cell carcinoma: a single center experience of six cases. BMC research notes, 2014, Dec-04, Volume: 7 Topics: Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Sunitinib	2014
Efficacy and Safety of an Attenuated-Dose Sunitinib Regimen in Metastatic Renal Cell Carcinoma: Results From a Prospective Registry in Singapore. Clinical genitourinary cancer, 2015, Volume: 13, Issue:4 Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Drug Administration Schedule; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Prospective Studies; Pyrroles; Singapore; Sunitinib; Survival Analysis; Treatment Outcome; Young Adult	2015
Gene expression profiling of sequential metastatic biopsies for biomarker discovery in breast cancer. Molecular oncology, 2015, Volume: 9, Issue:7 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy; Breast Neoplasms; Cell Hypoxia; Cell Proliferation; Docetaxel; Female; Gene Expression Profiling; Humans; Indoles; Middle Aged; Multimodal Imaging; Neoplasm Metastasis; Positron-Emission Tomography; Prospective Studies; Pyrroles; Sunitinib; Taxoids; Tomography, X-Ray Computed	2015
Myeloid-Derived Suppressor Cells as an Immune Parameter in Patients with Concurrent Sunitinib and Stereotactic Body Radiotherapy. Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, Sep-15, Volume: 21, Issue:18 Topics: Antineoplastic Agents; CD11b Antigen; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Proliferation; Cell Survival; Disease Progression; Flow Cytometry; Humans; Immune System; Immunosuppressive Agents; Indoles; Leukocytes, Mononuclear; Monocytes; Myeloid Cells; Neoplasm Metastasis; Neoplasms; Phosphorylation; Pyrroles; Radiosurgery; Sialic Acid Binding Ig-like Lectin 3; STAT3 Transcription Factor; Sunitinib; Treatment Outcome	2015
Effects of Adjuvant Sorafenib and Sunitinib on Cardiac Function in Renal Cell Carcinoma Patients without Overt Metastases: Results from ASSURE, ECOG 2805. Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, Sep-15, Volume: 21, Issue:18 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Cardiovascular Diseases; Chemotherapy, Adjuvant; Double-Blind Method; Female; Heart Failure; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Multivariate Analysis; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Prospective Studies; Pyrroles; Risk Factors; Sorafenib; Sunitinib; Ventricular Function, Left	2015
Phase 2 trial of sunitinib and gemcitabine in patients with sarcomatoid and/or poor-risk metastatic renal cell carcinoma. Cancer, 2015, Oct-01, Volume: 121, Issue:19 Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Deoxycytidine; Female; Gemcitabine; Humans; Indoles; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Sunitinib	2015
Trebananib (AMG 386) in Combination With Sunitinib in Patients With Metastatic Renal Cell Cancer: An Open-Label, Multicenter, Phase II Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Oct-20, Volume: 33, Issue:30 Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Cohort Studies; Drug Administration Schedule; Female; Humans; Indoles; Injections, Intravenous; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Recombinant Fusion Proteins; Sunitinib	2015
[In Process Citation]. Aktuelle Urologie, 2015, Volume: 46, Issue:5 Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Germany; Humans; Indoles; Ipilimumab; Kidney Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; Nivolumab; Prognosis; Pyrroles; Societies, Medical; Sunitinib; Urology	2015
The early effect of sunitinib on insulin clearance in patients with metastatic renal cell carcinoma. British journal of clinical pharmacology, 2016, Volume: 81, Issue:4 Topics: Adult; Aged; Antineoplastic Agents; Blood Glucose; Carcinoma, Renal Cell; Female; Glucose Clamp Technique; Humans; Hypoglycemia; Indoles; Insulin; Male; Middle Aged; Neoplasm Metastasis; Prospective Studies; Pyrroles; Sunitinib; Time Factors	2016
Evaluation of Safety and Efficacy of Salvage Therapy With Sunitinib, Docetaxel (Tyxan) and Cisplatinum Followed by Maintenance Vinorelbine for Unresectable/Metastatic Nonsmall Cell Lung Cancer: Stage 1 of a Simon 2 Stage Clinical Trial. [Corrected]. Medicine, 2015, Volume: 94, Issue:52 Topics: Adult; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cisplatin; Docetaxel; Female; Humans; Indoles; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Pyrroles; Salvage Therapy; Sunitinib; Survival Analysis; Taxoids; Treatment Outcome; Vinblastine; Vinorelbine	2015
Everolimus versus sunitinib for patients with metastatic non-clear cell renal cell carcinoma (ASPEN): a multicentre, open-label, randomised phase 2 trial. The Lancet. Oncology, 2016, Volume: 17, Issue:3 Topics: Adult; Aged; Carcinoma, Renal Cell; Confidence Intervals; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Everolimus; Female; Follow-Up Studies; Humans; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Staging; Proportional Hazards Models; Pyrroles; Sunitinib; Survival Analysis; Treatment Outcome	2016
Circulating biomarkers and outcome from a randomised phase II trial of sunitinib vs everolimus for patients with metastatic renal cell carcinoma. British journal of cancer, 2016, Mar-15, Volume: 114, Issue:6 Topics: Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Renal Cell; Cytokines; Everolimus; Humans; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Neoplasm Metastasis; Pyrroles; Sunitinib	2016
A Randomized, Open-Label Phase 2 Study of the CXCR4 Inhibitor LY2510924 in Combination with Sunitinib Versus Sunitinib Alone in Patients with Metastatic Renal Cell Carcinoma (RCC). Targeted oncology, 2016, Volume: 11, Issue:5 Topics: Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Female; Humans; Indoles; Male; Neoplasm Metastasis; Peptides, Cyclic; Pyrroles; Receptors, CXCR4; Sunitinib	2016
Efficacy and Safety of Regorafenib in Korean Patients with Advanced Gastrointestinal Stromal Tumor after Failure of Imatinib and Sunitinib: A Multicenter Study Based on the Management Access Program. Cancer research and treatment, 2017, Volume: 49, Issue:2 Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrroles; Retreatment; Sunitinib; Treatment Failure; Treatment Outcome	2017
BSA and ABCB1 polymorphism affect the pharmacokinetics of sunitinib and its active metabolite in Asian mRCC patients receiving an attenuated sunitinib dosing regimen. Cancer chemotherapy and pharmacology, 2016, Volume: 78, Issue:3 Topics: Aged; Antineoplastic Agents; Asian People; ATP Binding Cassette Transporter, Subfamily B; Body Surface Area; Carcinoma, Renal Cell; Female; Genotype; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Models, Biological; Monte Carlo Method; Neoplasm Metastasis; Nonlinear Dynamics; Polymorphism, Genetic; Pyrroles; Sunitinib	2016
IMA901, a multipeptide cancer vaccine, plus sunitinib versus sunitinib alone, as first-line therapy for advanced or metastatic renal cell carcinoma (IMPRINT): a multicentre, open-label, randomised, controlled, phase 3 trial. The Lancet. Oncology, 2016, Volume: 17, Issue:11 Topics: Aged; Cancer Vaccines; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Sunitinib	2016
Sunitinib for the treatment of benign and malignant neoplasms from von Hippel-Lindau disease: A single-arm, prospective phase II clinical study from the PREDIR group. Oncotarget, 2016, Dec-20, Volume: 7, Issue:51 Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Female; France; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Neoplasms; Prospective Studies; Pyrroles; Sunitinib; Survival Analysis; Treatment Outcome; von Hippel-Lindau Disease	2016
Patterns of Care and Clinical Outcomes in Patients With Metastatic Renal Cell Carcinoma-Results From a Tertiary Cancer Center in India. Clinical genitourinary cancer, 2017, Volume: 15, Issue:3 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Everolimus; Female; Humans; Indazoles; India; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Practice Patterns, Physicians'; Prospective Studies; Pyrimidines; Pyrroles; Retrospective Studies; Sirolimus; Sorafenib; Sulfonamides; Sunitinib; Survival Analysis; Tertiary Care Centers; Treatment Outcome; Young Adult	2017
Cabozantinib Versus Sunitinib As Initial Targeted Therapy for Patients With Metastatic Renal Cell Carcinoma of Poor or Intermediate Risk: The Alliance A031203 CABOSUN Trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, 02-20, Volume: 35, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Anilides; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Molecular Targeted Therapy; Neoplasm Metastasis; Pyridines; Pyrroles; Risk Factors; Sunitinib	2017
Quality of life in patients with metastatic renal cell carcinoma treated with sunitinib or interferon alfa: results from a phase III randomized trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Aug-01, Volume: 26, Issue:22 Topics: Administration, Oral; Antineoplastic Agents; Australia; Brazil; Canada; Carcinoma, Renal Cell; Drug Administration Schedule; Europe; Female; Health Status Indicators; Humans; Indoles; Injections, Subcutaneous; Interferon-alpha; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Quality of Life; Russia; Sunitinib; Surveys and Questionnaires; Treatment Outcome; United States	2008
Phase II trial of sunitinib for the therapy of progressive metastatic castration-refractory prostate cancer after previous docetaxel chemotherapy. Clinical genitourinary cancer, 2008, Volume: 6, Issue:2 Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents; Castration; Disease-Free Survival; Humans; Indoles; Male; Neoplasm Metastasis; Prostate-Specific Antigen; Prostatic Neoplasms; Pyrroles; Quality of Life; Sunitinib	2008
Cost-effectiveness analysis of sunitinib in patients with metastatic and/or unresectable gastrointestinal stroma tumours (GIST) after progression or intolerance with imatinib. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2008, Volume: 10, Issue:12 Topics: Algorithms; Antineoplastic Agents; Benzamides; Chemotherapy, Adjuvant; Cost-Benefit Analysis; Disease Progression; Double-Blind Method; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Health Resources; Humans; Imatinib Mesylate; Indoles; Markov Chains; Models, Econometric; Neoplasm Metastasis; Piperazines; Placebos; Pyrimidines; Pyrroles; Sunitinib; Survival Analysis; Treatment Failure	2008
18F-FDG PET/CT imaging for an early assessment of response to sunitinib in metastatic renal carcinoma: preliminary study. Cancer biotherapy & radiopharmaceuticals, 2009, Volume: 24, Issue:1 Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Disease-Free Survival; Female; Fluorodeoxyglucose F18; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Positron-Emission Tomography; Prognosis; Pyrroles; Radiopharmaceuticals; Sunitinib; Tomography, X-Ray Computed; Treatment Outcome	2009
Sunitinib treatment for patients with clear-cell metastatic renal cell carcinoma: clinical outcomes and plasma angiogenesis markers. BMC cancer, 2009, Mar-12, Volume: 9 Topics: Adenocarcinoma, Clear Cell; Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents; Biomarkers, Tumor; Disease-Free Survival; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neovascularization, Pathologic; Platelet-Derived Growth Factor; Prognosis; Pyrroles; Receptors, Platelet-Derived Growth Factor; Receptors, Vascular Endothelial Growth Factor; Sunitinib; Treatment Outcome; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2	2009
Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Aug-01, Volume: 27, Issue:22 Topics: Administration, Oral; Adult; Aged; Carcinoma, Renal Cell; Confidence Intervals; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Indoles; Injections, Subcutaneous; Interferon-alpha; Kaplan-Meier Estimate; Kidney Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Staging; Probability; Proportional Hazards Models; Pyrroles; Sunitinib; Survival Analysis; Treatment Outcome	2009
Phase 1 study of concurrent sunitinib and image-guided radiotherapy followed by maintenance sunitinib for patients with oligometastases: acute toxicity and preliminary response. Cancer, 2009, Aug-01, Volume: 115, Issue:15 Topics: Aged; Aged, 80 and over; Combined Modality Therapy; Disease-Free Survival; Female; Humans; Indoles; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Metastasis; Neoplasms; Patient Compliance; Pyrroles; Radiation Dosage; Sunitinib	2009
Sunitinib malate for metastatic castration-resistant prostate cancer following docetaxel-based chemotherapy. Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:2 Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Castration; Chemotherapy, Adjuvant; Disease-Free Survival; Docetaxel; Humans; Indoles; Male; Middle Aged; Neoplasm Metastasis; Prostatic Neoplasms; Pyrroles; Quality of Life; Sunitinib; Taxoids; Time Factors; Treatment Failure	2010
A phase II study of sunitinib in patients with recurrent and/or metastatic non-nasopharyngeal head and neck cancer. Cancer chemotherapy and pharmacology, 2010, Volume: 65, Issue:4 Topics: Aged; Angiogenesis Inhibitors; Anorexia; Area Under Curve; Carcinoma, Squamous Cell; Drug Administration Schedule; Fatigue; Female; Head and Neck Neoplasms; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Indoles; Male; Metabolic Clearance Rate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Pyrroles; Sunitinib; Survival Analysis; Thrombocytopenia; Treatment Outcome; Vascular Endothelial Growth Factor A	2010
A phase II study of sunitinib in patients with locally advanced or metastatic cervical carcinoma: NCIC CTG Trial IND.184. Gynecologic oncology, 2010, Volume: 116, Issue:2 Topics: Adult; Aged; Antineoplastic Agents; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Indoles; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Pyrroles; Sunitinib; Uterine Cervical Neoplasms	2010
Phase II study of sunitinib in recurrent or metastatic squamous cell carcinoma of the head and neck: GORTEC 2006-01. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Jan-01, Volume: 28, Issue:1 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Indoles; Magnetic Resonance Angiography; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Pyrroles; Sunitinib	2010
Safety and efficacy of combining sunitinib with bevacizumab + paclitaxel/carboplatin in non-small cell lung cancer. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2010, Volume: 5, Issue:3 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carboplatin; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cohort Studies; Female; Humans; Indoles; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Paclitaxel; Prognosis; Pyrroles; Safety; Sunitinib; Survival Rate	2010
Sunitinib malate and figitumumab in solitary fibrous tumor: patterns and molecular bases of tumor response. Molecular cancer therapeutics, 2010, Volume: 9, Issue:5 Topics: Adult; Aged; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Pharmacological; Biomarkers, Tumor; Disease Progression; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immunoglobulins, Intravenous; Indoles; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Receptor, Platelet-Derived Growth Factor beta; Solitary Fibrous Tumors; Sunitinib; Tomography, X-Ray Computed; Tumor Cells, Cultured	2010
Phase I dose-escalation study of brostallicin, a minor groove binder, in combination with cisplatin in patients with advanced solid tumors. Cancer chemotherapy and pharmacology, 2010, Volume: 66, Issue:2 Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dose-Response Relationship, Drug; Female; Guanidines; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Pyrroles; Sex Characteristics	2010
SABRE-B: an evaluation of paclitaxel and bevacizumab with or without sunitinib as first-line treatment of metastatic breast cancer. Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:12 Topics: Adult; Aged; Aged, 80 and over; Algorithms; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Breast Neoplasms; Carcinoma; Feasibility Studies; Female; Humans; Indoles; Middle Aged; Neoadjuvant Therapy; Neoplasm Metastasis; Paclitaxel; Pyrroles; Sunitinib; Treatment Outcome	2010
Metabolism, excretion, and pharmacokinetics of oral brivanib in patients with advanced or metastatic solid tumors. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:11 Topics: Administration, Oral; Aged; Alanine; Antineoplastic Agents; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Feces; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Pyrroles; Triazines	2010
Sorafenib in patients with metastatic renal cell carcinoma refractory to either sunitinib or bevacizumab. Cancer, 2010, Dec-01, Volume: 116, Issue:23 Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzenesulfonates; Bevacizumab; Carcinoma, Renal Cell; Drug Resistance, Neoplasm; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Pyridines; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Sorafenib; Sunitinib	2010
Phase II study of daily sunitinib in FDG-PET-positive, iodine-refractory differentiated thyroid cancer and metastatic medullary carcinoma of the thyroid with functional imaging correlation. Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, Nov-01, Volume: 16, Issue:21 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma; Carcinoma, Medullary; Cell Differentiation; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Fluorodeoxyglucose F18; Humans; Indoles; Iodine; Male; Middle Aged; Neoplasm Metastasis; Positron-Emission Tomography; Pyrroles; Sunitinib; Thyroid Neoplasms; Tomography, Emission-Computed; Treatment Failure	2010
The impact of sunitinib-induced hypothyroidism on progression-free survival of metastatic renal cancer patients: a prospective single-center study. Urologic oncology, 2012, Volume: 30, Issue:5 Topics: Aged; Angiogenesis Inhibitors; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Hypothyroidism; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Prospective Studies; Pyrroles; Sunitinib; Thyroid Function Tests; Thyrotropin; Time Factors; Treatment Outcome	2012
Phase 1 dose-escalation trial of tremelimumab plus sunitinib in patients with metastatic renal cell carcinoma. Cancer, 2011, Feb-15, Volume: 117, Issue:4 Topics: Acute Kidney Injury; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Colitis; Death, Sudden; Drug Administration Schedule; Female; Humans; Indoles; Kidney Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Metastasis; Pyrroles; Sunitinib	2011
The effect of sunitinib on immune subsets in metastatic clear cell renal cancer. Urologia internationalis, 2011, Volume: 86, Issue:1 Topics: Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney Neoplasms; Lymphocytes; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Sunitinib; Treatment Outcome	2011
Phase II study of sunitinib malate, a multitargeted tyrosine kinase inhibitor in patients with relapsed or refractory soft tissue sarcomas. Focus on three prevalent histologies: leiomyosarcoma, liposarcoma and malignant fibrous histiocytoma. International journal of cancer, 2011, Oct-15, Volume: 129, Issue:8 Topics: Disease-Free Survival; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Histiocytoma, Malignant Fibrous; Humans; Indoles; Leiomyosarcoma; Liposarcoma; Male; Neoplasm Metastasis; Protein Kinase Inhibitors; Pyrroles; Recurrence; Retreatment; Sarcoma; Sunitinib; Survival Rate	2011
MVA-5T4-induced immune responses are an early marker of efficacy in renal cancer patients. Cancer immunology, immunotherapy : CII, 2011, Volume: 60, Issue:6 Topics: Aged; Antibodies, Neoplasm; Cancer Vaccines; Carcinoma, Renal Cell; Female; Humans; Indoles; Interferon-alpha; Interleukin-2; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Sunitinib; Vaccines, DNA	2011
A phase I study of sunitinib in combination with FOLFIRI in patients with untreated metastatic colorectal cancer. Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:1 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Female; Fluorouracil; Humans; Indoles; Leucovorin; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Metastasis; Pyrroles; Sunitinib	2012
A phase I pharmacokinetic study of TSU-68 (a multiple tyrosine kinase inhibitor of VEGFR-2, FGF and PDFG) in combination with S-1 and oxaliplatin in metastatic colorectal cancer patients previously treated with chemotherapy. Investigational new drugs, 2012, Volume: 30, Issue:4 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Combinations; Female; Fibroblast Growth Factors; Humans; Indoles; Male; Middle Aged; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Oxindoles; Oxonic Acid; Platelet-Derived Growth Factor; Propionates; Protein Kinase Inhibitors; Pyrroles; Tegafur; Treatment Outcome; Vascular Endothelial Growth Factor Receptor-2	2012
An adjusted indirect comparison of everolimus and sorafenib therapy in sunitinib-refractory metastatic renal cell carcinoma patients using repeated matched samples. Expert opinion on pharmacotherapy, 2011, Volume: 12, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Disease-Free Survival; Drug Resistance, Neoplasm; Everolimus; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Pyridines; Pyrroles; Sirolimus; Sorafenib; Sunitinib; Survival; Treatment Outcome	2011
Phase II study of sunitinib as maintenance therapy in patients with locally advanced or metastatic non-small cell lung cancer. Lung cancer (Amsterdam, Netherlands), 2011, Volume: 74, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Disease Progression; Female; Follow-Up Studies; Humans; Indoles; Lung Neoplasms; Maintenance Chemotherapy; Male; Middle Aged; Neoplasm Metastasis; Paclitaxel; Pyrroles; Sunitinib; Survival Analysis	2011
Metastatic renal cell carcinoma: relationship between initial metastasis hypoxia, change after 1 month's sunitinib, and therapeutic response: an 18F-fluoromisonidazole PET/CT study. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2011, Volume: 52, Issue:7 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carcinoma, Renal Cell; Cell Hypoxia; Cohort Studies; Disease Progression; Humans; Indoles; Kidney Neoplasms; Middle Aged; Misonidazole; Neoplasm Metastasis; Positron-Emission Tomography; Prognosis; Pyrroles; Sunitinib; Survival Analysis; Time Factors; Tomography, X-Ray Computed; Treatment Outcome; Young Adult	2011
Multikinase inhibitors in metastatic renal cell carcinoma: indirect comparison meta-analysis. Clinical therapeutics, 2011, Volume: 33, Issue:6 Topics: Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Humans; Indazoles; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Pyrroles; Sorafenib; Sulfonamides; Sunitinib	2011
Sequential FDG-PET/CT as a biomarker of response to Sunitinib in metastatic clear cell renal cancer. Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Sep-15, Volume: 17, Issue:18 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Female; Fluorodeoxyglucose F18; Humans; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Male; Middle Aged; Multimodal Imaging; Neoplasm Metastasis; Positron-Emission Tomography; Prognosis; Pyrroles; Sunitinib; Tomography, X-Ray Computed; Treatment Outcome	2011
A phase II study of presurgical sunitinib in patients with metastatic clear-cell renal carcinoma and the primary tumor in situ. Urology, 2011, Volume: 78, Issue:4 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Combined Modality Therapy; Disease Progression; Disease-Free Survival; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Probability; Prospective Studies; Pyrroles; Sunitinib; Treatment Outcome	2011
Sunitinib in combination with docetaxel and prednisone in chemotherapy-naive patients with metastatic, castration-resistant prostate cancer: a phase 1/2 clinical trial. Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:3 Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Docetaxel; Drug Resistance, Neoplasm; Humans; Indoles; Kaplan-Meier Estimate; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prednisone; Prostate-Specific Antigen; Prostatic Neoplasms; Pyrroles; Sunitinib; Taxoids	2012
Phase II trial of continuous once-daily dosing of sunitinib as first-line treatment in patients with metastatic renal cell carcinoma. Cancer, 2012, Mar-01, Volume: 118, Issue:5 Topics: Adult; Aged; Carcinoma, Renal Cell; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Metastasis; Pyrroles; Sunitinib; Survival Analysis; Young Adult	2012
Multicenter phase II study of sunitinib in patients with non-clear cell renal cell carcinoma. Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:8 Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Prospective Studies; Pyrroles; Sunitinib; Young Adult	2012
First-line sunitinib plus FOLFIRI in Japanese patients with unresectable/metastatic colorectal cancer: a phase II study. Cancer science, 2012, Volume: 103, Issue:8 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asian People; Camptothecin; Colorectal Neoplasms; Disease-Free Survival; Female; Fluorouracil; Humans; Indoles; Leucovorin; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Sunitinib; Treatment Outcome	2012
Q-TWiST analysis to estimate overall benefit for patients with metastatic renal cell carcinoma treated in a phase III trial of sunitinib vs interferon-α. British journal of cancer, 2012, May-08, Volume: 106, Issue:10 Topics: Angiogenesis Inhibitors; Carcinoma, Renal Cell; Disease-Free Survival; Humans; Indoles; Interferon-alpha; Kidney Neoplasms; Neoplasm Metastasis; Pyrroles; Sunitinib	2012
Efficacy and safety of regorafenib in patients with metastatic and/or unresectable GI stromal tumor after failure of imatinib and sunitinib: a multicenter phase II trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jul-01, Volume: 30, Issue:19 Topics: Adult; Aged; Antineoplastic Agents; Benzamides; Disease-Free Survival; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Neoplasm Metastasis; Phenylurea Compounds; Piperazines; Pyridines; Pyrimidines; Pyrroles; Sunitinib; Treatment Outcome	2012
Sunitinib plus erlotinib for the treatment of advanced/metastatic non-small-cell lung cancer: a lead-in study. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2012, Volume: 7, Issue:9 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cohort Studies; Double-Blind Method; Erlotinib Hydrochloride; Female; Follow-Up Studies; Humans; Indoles; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Prognosis; Pyrroles; Quinazolines; Sunitinib; Survival Rate; Tissue Distribution	2012
Phase II trial of concurrent sunitinib and image-guided radiotherapy for oligometastases. PloS one, 2012, Volume: 7, Issue:6 Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Chemoradiotherapy; Dose Fractionation, Radiation; Female; Follow-Up Studies; Humans; Indoles; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Prognosis; Pyrroles; Radiotherapy, Image-Guided; Sunitinib; Survival Rate	2012
An indirect comparison of the toxicity of sunitinib and pazopanib in metastatic clear cell renal cancer. European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:17 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Female; Humans; Indazoles; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Prospective Studies; Pyrimidines; Pyrroles; Sulfonamides; Sunitinib	2012
A phase I study of BMS-690514 in Japanese patients with advanced or metastatic solid tumors. Cancer chemotherapy and pharmacology, 2012, Volume: 70, Issue:4 Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Female; Fluorodeoxyglucose F18; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Piperidines; Positron-Emission Tomography; Pyrroles; Triazines	2012
Soluble KIT correlates with clinical outcome in patients with metastatic breast cancer treated with sunitinib. Journal of translational medicine, 2012, Aug-16, Volume: 10 Topics: Adult; Aged; Antineoplastic Agents; Biomarkers, Tumor; Breast Neoplasms; Female; Humans; Indoles; Middle Aged; Neoplasm Metastasis; Proto-Oncogene Proteins c-kit; Pyrroles; Sunitinib; Treatment Outcome	2012
An exploratory study of sunitinib in combination with docetaxel and trastuzumab as first-line therapy for HER2-positive metastatic breast cancer. Breast (Edinburgh, Scotland), 2012, Volume: 21, Issue:6 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disease-Free Survival; Docetaxel; Drug Administration Schedule; Feasibility Studies; Female; Humans; Indoles; Infusions, Intravenous; Kaplan-Meier Estimate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Pyrroles; Receptor, ErbB-2; Sunitinib; Taxoids; Trastuzumab; Treatment Outcome	2012
A pilot study of sunitinib malate in patients with metastatic uveal melanoma. Melanoma research, 2012, Volume: 22, Issue:6 Topics: Adult; Aged; Female; Humans; Indoles; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Pilot Projects; Prognosis; Proto-Oncogene Proteins c-kit; Pyrroles; Sunitinib; Treatment Outcome; Uveal Neoplasms	2012
Prognostic value of serum CA9 in patients with metastatic clear cell renal cell carcinoma under targeted therapy. Anticancer research, 2012, Volume: 32, Issue:12 Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Renal Cell; Enzyme-Linked Immunosorbent Assay; Female; Humans; Indoles; Interferon-alpha; Kidney Neoplasms; Male; Middle Aged; Molecular Targeted Therapy; Neoplasm Metastasis; Pyrroles; Sirolimus; Sunitinib; Treatment Outcome	2012
Phase II study of sunitinib in Japanese patients with unresectable or metastatic, well-differentiated pancreatic neuroendocrine tumor. Investigational new drugs, 2013, Volume: 31, Issue:5 Topics: Adult; Aged; Angiogenesis Inhibitors; Asian People; Biomarkers, Tumor; Chromogranin A; Female; Gastrins; Humans; Indoles; Male; Middle Aged; Neoplasm Metastasis; Neuroendocrine Tumors; Pancreatic Neoplasms; Pyrroles; Sunitinib; Treatment Outcome	2013
Fluorouracil, leucovorin, and irinotecan plus either sunitinib or placebo in metastatic colorectal cancer: a randomized, phase III trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Apr-01, Volume: 31, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Diarrhea; Double-Blind Method; Drug Administration Schedule; Fatigue; Female; Fluorouracil; Humans; Indoles; Irinotecan; Kaplan-Meier Estimate; Leucovorin; Male; Middle Aged; Neoplasm Metastasis; Neutropenia; Pyrroles; Sunitinib; Thrombocytopenia; Treatment Outcome	2013
Phase II study of the Flk-1 tyrosine kinase inhibitor SU5416 in advanced melanoma. Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Jun-15, Volume: 10, Issue:12 Pt 1 Topics: Adult; Aged; Angiogenesis Inhibitors; Female; Glucose; Humans; Indoles; Lymphocytes; Magnetic Resonance Imaging; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Neovascularization, Pathologic; Protein Kinase Inhibitors; Pyrroles; Time Factors; Treatment Outcome; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2	2004
Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Jan-01, Volume: 24, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Quality of Life; Receptors, Platelet-Derived Growth Factor; Receptors, Vascular Endothelial Growth Factor; Sunitinib	2006
Phase I/pilot study of SU5416 (semaxinib) in combination with irinotecan/bolus 5-FU/LV (IFL) in patients with metastatic colorectal cancer. American journal of clinical oncology, 2006, Volume: 29, Issue:2 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Indoles; Infusions, Intravenous; Injections, Intravenous; Irinotecan; Leucovorin; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Vascular Endothelial Growth Factor Receptor-2	2006
A phase II, pharmacokinetic, and biologic study of semaxanib and thalidomide in patients with metastatic melanoma. Cancer chemotherapy and pharmacology, 2007, Volume: 59, Issue:2 Topics: Adult; Aged; Angiogenesis Inhibitors; Area Under Curve; Asthenia; Dose-Response Relationship, Drug; Edema; Female; Half-Life; Headache; Humans; Indoles; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Peripheral Nervous System Diseases; Protein Kinase Inhibitors; Pyrroles; Thalidomide; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Venous Thrombosis	2007
Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma and various other solid tumors. The Journal of steroid biochemistry and molecular biology, 2008, Volume: 108, Issue:3-5 Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Renal Cell; Female; Gastrointestinal Stromal Tumors; Humans; Indoles; Kidney Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neuroendocrine Tumors; Pyrroles; Receptors, Platelet-Derived Growth Factor; Receptors, Vascular Endothelial Growth Factor; Sunitinib	2008

Other Studies

292 other study(ies) available for pyrroles and Metastase

Article	Year
Identification of TRPV4 as a novel target in invasiveness of colorectal cancer. BMC cancer, 2021, Nov-23, Volume: 21, Issue:1 Topics: Cell Line, Tumor; Cell Movement; Colonic Neoplasms; Epithelial-Mesenchymal Transition; Female; HCT116 Cells; Humans; Immunohistochemistry; Male; Middle Aged; Morpholines; Neoplasm Invasiveness; Neoplasm Metastasis; Proto-Oncogene Proteins c-akt; Pyrroles; Rectal Neoplasms; RNA, Small Interfering; Transfection; TRPV Cation Channels; Zinc Finger E-box-Binding Homeobox 1	2021
MicroRNA-148b-colony-stimulating factor-1 signaling-induced tumor-associated macrophage infiltration promotes hepatocellular carcinoma metastasis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 120 Topics: Aminopyridines; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Macrophage Colony-Stimulating Factor; Macrophages; Male; Mice; Mice, Nude; MicroRNAs; Neoplasm Metastasis; Neoplasms, Experimental; Pyrroles; Signal Transduction	2019
Preseptal cellulitis, intraocular inflammatory reaction and corneal persistent epithelial defect as side effects of avapritinib. Anti-cancer drugs, 2021, 11-01, Volume: 32, Issue:10 Topics: Aged; Antineoplastic Agents; Cellulitis; Epithelium, Corneal; Eye Diseases; Female; Gastrointestinal Stromal Tumors; Humans; Inflammation; Neoplasm Metastasis; Neoplasm Staging; Pyrazoles; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Triazines	2021
Gastrointestinal stromal tumor of the stomach with axillary lymph node metastasis: A case report. World journal of gastroenterology, 2017, Mar-07, Volume: 23, Issue:9 Topics: Aged; Axilla; Fatal Outcome; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Lymph Nodes; Lymphatic Metastasis; Male; Neoplasm Metastasis; Phenylurea Compounds; Positron-Emission Tomography; Pyridines; Pyrroles; Stomach Neoplasms; Sunitinib; Tomography, X-Ray Computed	2017
Sunitinib 4/2 Versus 2/1 Schedule for Patients With Metastatic Renal Cell Carcinoma: Tertiary Care Hospital Experience. Clinical genitourinary cancer, 2017, Volume: 15, Issue:3 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Retrospective Studies; Sunitinib; Tertiary Care Centers; Treatment Outcome; Young Adult	2017
Evaluation of KDR rs34231037 as a predictor of sunitinib efficacy in patients with metastatic renal cell carcinoma. Pharmacogenetics and genomics, 2017, Volume: 27, Issue:6 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Indoles; Kidney Neoplasms; Male; Neoplasm Metastasis; Pharmacogenomic Variants; Polymorphism, Single Nucleotide; Pyrroles; Sunitinib; Treatment Outcome; Tumor Burden	2017
Potential health gains for patients with metastatic renal cell carcinoma in daily clinical practice: A real-world cost-effectiveness analysis of sequential first- and second-line treatments. PloS one, 2017, Volume: 12, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Cost of Illness; Cost-Benefit Analysis; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Netherlands; Pyrroles; Quality-Adjusted Life Years; Registries; Regression Analysis; Sunitinib; Treatment Outcome; Young Adult	2017
Dose individualization of sunitinib in metastatic renal cell cancer: toxicity-adjusted dose or therapeutic drug monitoring. Cancer chemotherapy and pharmacology, 2017, Volume: 80, Issue:2 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Prospective Studies; Pyrroles; Sunitinib; Survival Rate; Time Factors	2017
Outcomes of Patients With Long-Term Treatment Response to Vascular Endothelial Growth Factor-Targeted Therapy for Metastatic Renal Cell Cancer. Clinical genitourinary cancer, 2017, Volume: 15, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Bevacizumab; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Indazoles; Indoles; Kidney Neoplasms; Male; Middle Aged; Molecular Targeted Therapy; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Pyrimidines; Pyrroles; Registries; Retrospective Studies; Sorafenib; Sulfonamides; Sunitinib; Survival Analysis; Treatment Outcome; Vascular Endothelial Growth Factor A	2017
Comparison of efficacy, safety, and quality of life between sorafenib and sunitinib as first-line therapy for Chinese patients with metastatic renal cell carcinoma. Chinese journal of cancer, 2017, Aug-08, Volume: 36, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Renal Cell; China; Disease-Free Survival; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Indoles; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyrroles; Quality of Life; Sorafenib; Sunitinib; Treatment Outcome	2017
CAY10591, a SIRT1 activator, suppresses cell growth, invasion, and migration in gingival epithelial carcinoma cells. Journal of oral science, 2017, Volume: 59, Issue:3 Topics: Cell Division; Cell Line, Tumor; Cyclopentanes; Dimethyl Sulfoxide; Gingival Neoplasms; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Pyrroles; Quinoxalines; Reverse Transcriptase Polymerase Chain Reaction; Sirtuin 1	2017
Expression of tyrosine kinase receptor AXL is associated with worse outcome of metastatic renal cell carcinomas treated with sunitinib. Urologic oncology, 2018, Volume: 36, Issue:1 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Female; Humans; Immunohistochemistry; Indoles; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Receptor Protein-Tyrosine Kinases; Sunitinib; Treatment Outcome	2018
Near infrared imaging of Mer tyrosine kinase (MERTK) using MERi-SiR reveals tumor associated macrophage uptake in metastatic disease. Chemical communications (Cambridge, England), 2017, Dec-19, Volume: 54, Issue:1 Topics: Animals; Binding Sites; c-Mer Tyrosine Kinase; Cell Line, Tumor; Cell Proliferation; Fluorescent Dyes; Macrophages; Mice; Microscopy, Confocal; Molecular Docking Simulation; Neoplasm Metastasis; Neoplasms; Protein Structure, Tertiary; Pyrimidines; Pyrroles; RNA Interference; RNA, Small Interfering; Signal Transduction; Spectroscopy, Near-Infrared; Structure-Activity Relationship	2017
Prognostic effect of cytoreductive nephrectomy in synchronous metastatic renal cell carcinoma: a comparative study using inverse probability of treatment weighting. World journal of urology, 2018, Volume: 36, Issue:3 Topics: Aged; Anilides; Antibodies, Monoclonal; Antineoplastic Agents; Carcinoma, Renal Cell; Cohort Studies; Combined Modality Therapy; Cytoreduction Surgical Procedures; Female; Humans; Indazoles; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Molecular Targeted Therapy; Neoplasm Metastasis; Nephrectomy; Nivolumab; Probability; Prognosis; Proportional Hazards Models; Pyridines; Pyrimidines; Pyrroles; Retrospective Studies; Sex Factors; Sulfonamides; Sunitinib; Survival Rate; Thrombocytosis	2018
Efficacy and safety of sunitinib alternate day regimen in patients with metastatic renal cell carcinoma in Japan: Comparison with standard 4/2 schedule. Asia-Pacific journal of clinical oncology, 2018, Volume: 14, Issue:3 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Female; Humans; Indoles; Japan; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Sunitinib	2018
Dose escalation can maximize therapeutic potential of sunitinib in patients with metastatic renal cell carcinoma. BMC cancer, 2018, 03-15, Volume: 18, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Renal Cell; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Indoles; Male; Middle Aged; Neoplasm Metastasis; Nephrectomy; Pyrroles; Sunitinib; Treatment Outcome	2018
Evaluation of relative dose intensity during the early phase of first-line sunitinib treatment using a 2-week-on/1-week-off regimen for metastatic renal cell carcinoma. Medical oncology (Northwood, London, England), 2018, Apr-23, Volume: 35, Issue:6 Topics: Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Retrospective Studies; Sunitinib	2018
Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis. Science translational medicine, 2018, 05-16, Volume: 10, Issue:441 Topics: Animals; Cell Line, Tumor; Cell Nucleolus; Cell Proliferation; Chromatin; DNA, Ribosomal; Humans; Male; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Pancreatic Neoplasms; Peptide Elongation Factor 1; Promoter Regions, Genetic; Pyrimidines; Pyrroles; RNA Polymerase I; RNA Precursors; Survival Analysis; Transcription, Genetic; Xenograft Model Antitumor Assays	2018
Significance of Age in Japanese Patients Receiving Sunitinib as First-line Systemic Therapy for Metastatic Renal Cell Carcinoma: Comparative Assessment of Efficacy and Safety between Patients Aged <75 and ≥75 Years. Anticancer research, 2018, Volume: 38, Issue:6 Topics: Aged; Aged, 80 and over; Aging; Antineoplastic Agents; Asian People; Carcinoma, Renal Cell; Disease-Free Survival; Fatigue; Female; Humans; Indoles; Japan; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Retrospective Studies; Sunitinib; Thrombocytopenia; Treatment Outcome	2018
Retrospective analysis on the efficacy of sunitinib/sorafenib in combination with dendritic cells-cytokine-induced killer in metastasis renal cell carcinoma after radical nephrectomy. Journal of cancer research and therapeutics, 2018, Volume: 14, Issue:Supplement Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cancer Vaccines; Carcinoma, Renal Cell; Combined Modality Therapy; Cytokine-Induced Killer Cells; Dendritic Cells; Female; Humans; Immunotherapy, Adoptive; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Niacinamide; Phenylurea Compounds; Postoperative Care; Pyrroles; Retrospective Studies; Sorafenib; Sunitinib; Survival Analysis; Treatment Outcome	2018
Early ctDNA dynamics as a surrogate for progression-free survival in advanced breast cancer in the BEECH trial. Annals of oncology : official journal of the European Society for Medical Oncology, 2019, 06-01, Volume: 30, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Circulating Tumor DNA; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cohort Studies; Double-Blind Method; Female; Follow-Up Studies; Humans; Neoplasm Metastasis; Paclitaxel; Prognosis; Progression-Free Survival; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Survival Rate	2019
Synergistic triple-combination therapy with hyaluronic acid-shelled PPy/CPT nanoparticles results in tumor regression and prevents tumor recurrence and metastasis in 4T1 breast cancer. Biomaterials, 2019, Volume: 217 Topics: Animals; Camptothecin; Cell Line, Tumor; Combined Modality Therapy; Female; Fluorescence; Hyaluronic Acid; Hyperthermia, Induced; Immunity; Immunotherapy; Mammary Neoplasms, Animal; Mice; Nanoparticles; Neoplasm Metastasis; Neoplasm Recurrence, Local; Optical Imaging; Photoacoustic Techniques; Phototherapy; Polymers; Pyrroles; Tissue Distribution	2019
Sotrastaurin attenuates the stemness of gastric cancer cells by targeting PKCδ. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 117 Topics: Cell Line, Tumor; Doxorubicin; Drug Resistance, Neoplasm; Humans; Neoplasm Metastasis; Neoplastic Stem Cells; Protein Kinase C-delta; Pyrroles; Quinazolines; Stomach Neoplasms	2019
BH3 mimetics reduce adhesion and migration of hepatoblastoma and hepatocellular carcinoma cells. Experimental cell research, 2013, Jun-10, Volume: 319, Issue:10 Topics: Actins; Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Blotting, Western; Carcinoma, Hepatocellular; Caspase 3; Caspase 7; Caspase Inhibitors; cdc42 GTP-Binding Protein; Cell Adhesion; Cell Movement; Cytoskeleton; Enzyme Activation; Fluorescent Antibody Technique; Hepatoblastoma; Humans; Indoles; Neoplasm Metastasis; Nitrophenols; Oligopeptides; Piperazines; Proteolysis; Pseudopodia; Pyrroles; Sulfonamides	2013
VEGFR1 single nucleotide polymorphisms associated with outcome in patients with metastatic renal cell carcinoma treated with sunitinib - a multicentric retrospective analysis. Acta oncologica (Stockholm, Sweden), 2014, Volume: 53, Issue:1 Topics: Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Renal Cell; Female; Follow-Up Studies; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Grading; Neoplasm Metastasis; Polymorphism, Single Nucleotide; Prognosis; Pyrroles; Retrospective Studies; Sunitinib; Survival Rate; Treatment Outcome; Vascular Endothelial Growth Factor Receptor-1	2014
Sarcopenia and body mass index predict sunitinib-induced early dose-limiting toxicities in renal cancer patients. British journal of cancer, 2013, Mar-19, Volume: 108, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antineoplastic Agents; Body Mass Index; Carcinoma, Renal Cell; Female; Forecasting; Humans; Indoles; Kidney Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Metastasis; Pyrroles; Retrospective Studies; Sarcopenia; Sunitinib	2013
Single-nucleotide polymorphisms associated with outcome in metastatic renal cell carcinoma treated with sunitinib. British journal of cancer, 2013, Mar-05, Volume: 108, Issue:4 Topics: Angiogenesis Inhibitors; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Indoles; Kidney Neoplasms; Male; Neoplasm Metastasis; Polymorphism, Single Nucleotide; Pyrroles; Retrospective Studies; Sunitinib; Treatment Outcome	2013
Second line treatment of metastatic renal cell carcinoma: The Institut Gustave Roussy experience with targeted therapies in 251 consecutive patients. European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:8 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoma, Renal Cell; Cardiovascular Diseases; Disease Progression; Drug Administration Schedule; Everolimus; Female; Follow-Up Studies; Humans; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Pyrroles; Sirolimus; Sorafenib; Sunitinib; Treatment Outcome; Young Adult	2013
Design and pharmacology of a highly specific dual FMS and KIT kinase inhibitor. Proceedings of the National Academy of Sciences of the United States of America, 2013, Apr-02, Volume: 110, Issue:14 Topics: Aminopyridines; Animals; Cell Survival; Chromatography, Affinity; Crystallization; Escherichia coli; Human Umbilical Vein Endothelial Cells; Humans; Indoles; Inflammation; Macrophages; Mast Cells; Models, Molecular; Molecular Structure; Mutation, Missense; Neoplasm Metastasis; Oncogene Protein gp140(v-fms); Osteoclasts; Protein Conformation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrroles; Sf9 Cells; Spodoptera	2013
VEGF and VEGFR polymorphisms affect clinical outcome in advanced renal cell carcinoma patients receiving first-line sunitinib. British journal of cancer, 2013, Mar-19, Volume: 108, Issue:5 Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Polymorphism, Single Nucleotide; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Sunitinib; Treatment Outcome; Vascular Endothelial Growth Factor A	2013
Anti-angiogenic and anti-metastatic activity of synthetic phosphoethanolamine. PloS one, 2013, Volume: 8, Issue:3 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Renal Cell; Caspase 3; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclin D1; Cytoskeleton; Ethanolamines; Gene Expression Regulation, Neoplastic; Human Umbilical Vein Endothelial Cells; Humans; Indoles; Kidney Tubules, Proximal; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mitochondria; Neoplasm Metastasis; Neovascularization, Pathologic; Oxidation-Reduction; Pyrroles; Rats; Sunitinib; Transcription, Genetic; Vascular Endothelial Growth Factor Receptor-1; Wound Healing	2013
Comparative efficacy of sunitinib versus sorafenib as first-line treatment for patients with metastatic renal cell carcinoma. Chemotherapy, 2012, Volume: 58, Issue:6 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Multivariate Analysis; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Prognosis; Pyrroles; Retrospective Studies; Risk Factors; Sorafenib; Sunitinib; Survival Rate; Treatment Outcome; Young Adult	2012
No rebound tumour growth after sunitinib treatment. The Lancet. Oncology, 2013, Volume: 14, Issue:3 Topics: Humans; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Pyrroles; Sunitinib; Survival Analysis	2013
The efficacy and tolerability of a sunitinib 3-week administration schedule in metastatic renal cell carcinoma patients: report of three cases. Oncology research, 2012, Volume: 20, Issue:5-6 Topics: Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Drug Administration Schedule; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Sunitinib	2012
A model of postsurgical advanced metastatic breast cancer more accurately replicates the clinical efficacy of antiangiogenic drugs. Cancer research, 2013, May-01, Volume: 73, Issue:9 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Indoles; Mice; Mice, SCID; Neoplasm Metastasis; Neoplasm Transplantation; Pyrroles; Randomized Controlled Trials as Topic; Research Design; Sunitinib; Time Factors; Treatment Outcome	2013
Prolonged exposure to tyrosine kinase inhibitors or early use of everolimus in metastatic renal cell carcinoma: are the two options alike? Medical oncology (Northwood, London, England), 2013, Volume: 30, Issue:2 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Everolimus; Female; Humans; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrroles; Retrospective Studies; Sirolimus; Sorafenib; Sunitinib	2013
Atorvastatin inhibits RhoC function and limits head and neck cancer metastasis. Oral oncology, 2013, Volume: 49, Issue:8 Topics: Animals; Atorvastatin; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; MAP Kinase Signaling System; Mice; Neoplasm Metastasis; Phosphorylation; Pyrroles; rho GTP-Binding Proteins; rhoC GTP-Binding Protein; STAT3 Transcription Factor	2013
Prognostic and predictive value of hematologic parameters in patients with metastatic renal cell carcinoma: second line sunitinib treatment following IFN-alpha. Asian Pacific journal of cancer prevention : APJCP, 2013, Volume: 14, Issue:3 Topics: Adult; Aged; Angiogenesis Inhibitors; Antiviral Agents; Biomarkers, Tumor; Carcinoma, Renal Cell; Female; Follow-Up Studies; Hematologic Tests; Humans; Indoles; Interferon-alpha; Kidney Neoplasms; Lymphocytes; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Neutrophils; Prognosis; Pyrroles; Retrospective Studies; Sunitinib; Survival Rate	2013
JAK3 deregulation by activating mutations confers invasive growth advantage in extranodal nasal-type natural killer cell lymphoma. Leukemia, 2014, Volume: 28, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Animals; Case-Control Studies; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Humans; Janus Kinase 3; Lymphoma, Extranodal NK-T-Cell; Male; Mice; Middle Aged; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Staging; Phosphorylation; Piperidines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Tumor Burden; Xenograft Model Antitumor Assays	2014
Prognostic factors for survival in 1059 patients treated with sunitinib for metastatic renal cell carcinoma. British journal of cancer, 2013, Jun-25, Volume: 108, Issue:12 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Multivariate Analysis; Neoplasm Metastasis; Prognosis; Pyrroles; Retrospective Studies; Sunitinib; Survival Analysis; Survival Rate; Young Adult	2013
Prospective study assessing hypoxia-related proteins as markers for the outcome of treatment with sunitinib in advanced clear-cell renal cell carcinoma. Annals of oncology : official journal of the European Society for Medical Oncology, 2013, Volume: 24, Issue:9 Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antineoplastic Agents; Basic Helix-Loop-Helix Transcription Factors; Biomarkers, Tumor; Carcinoma, Renal Cell; Cell Hypoxia; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Gene Expression; Humans; Hypoxia-Inducible Factor-Proline Dioxygenases; Immunohistochemistry; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Prospective Studies; Pyrroles; RNA, Messenger; Sunitinib; Survival; Treatment Outcome; Vascular Endothelial Growth Factor Receptor-3	2013
Development and validation of a prognostic model in patients with metastatic renal cell carcinoma treated with sunitinib: a European collaboration. British journal of cancer, 2013, Jul-23, Volume: 109, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Cohort Studies; European Union; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Models, Statistical; Neoplasm Metastasis; Predictive Value of Tests; Prognosis; Pyrroles; Sunitinib; Survival Analysis	2013
Tissue slice grafts of human renal cell carcinoma: an authentic preclinical model with high engraftment rate and metastatic potential. Urologic oncology, 2014, Volume: 32, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Amino Acid Sequence; Animals; Antineoplastic Agents; Base Sequence; Biomarkers, Tumor; Carcinoma, Renal Cell; Female; Gene Expression Profiling; Graft Survival; Humans; Indoles; Kidney Neoplasms; Male; Mice; Mice, Knockout; Middle Aged; Molecular Sequence Data; Neoplasm Metastasis; Pyrroles; Sequence Homology, Amino Acid; Sunitinib; Transplantation, Heterologous; Von Hippel-Lindau Tumor Suppressor Protein; Xenograft Model Antitumor Assays	2014
Chemotherapy counteracts metastatic dissemination induced by antiangiogenic treatment in mice. Molecular cancer therapeutics, 2013, Volume: 12, Issue:10 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Lewis Lung; Cell Movement; Cisplatin; Deoxycytidine; Doxorubicin; Gemcitabine; Humans; Indoles; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Paclitaxel; Protein Kinase Inhibitors; Pyrroles; Sunitinib; Topotecan	2013
Evaluation of efficacy and safety of sunitinib regimen in 22 patients with metastatic renal cell carcinoma: at least 12-month follow-up. Chinese medical journal, 2013, Volume: 126, Issue:15 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Sunitinib; Young Adult	2013
[A case of metastatic renal cell carcinoma associated with Birt-Hogg-Dubé syndrome treated with molecular-targeting agents]. Hinyokika kiyo. Acta urologica Japonica, 2013, Volume: 59, Issue:8 Topics: Animals; Antineoplastic Agents; Birt-Hogg-Dube Syndrome; Carcinoma, Renal Cell; Everolimus; Humans; In Vitro Techniques; Indoles; Kidney Neoplasms; Male; Mice, Knockout; Middle Aged; Molecular Targeted Therapy; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Pyrroles; Sirolimus; Sorafenib; Sunitinib	2013
Clinical outcomes for patients with metastatic renal cell carcinoma treated with alternative sunitinib schedules. The Journal of urology, 2014, Volume: 191, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Disease Progression; Drug Administration Schedule; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Retrospective Studies; Sunitinib; Survival Rate; Treatment Outcome	2014
Differential inhibition of ex-vivo tumor kinase activity by vemurafenib in BRAF(V600E) and BRAF wild-type metastatic malignant melanoma. PloS one, 2013, Volume: 8, Issue:8 Topics: Aged; Cell Line, Tumor; Cluster Analysis; ErbB Receptors; Female; Humans; Indoles; Male; Melanoma; Middle Aged; Mutant Proteins; Mutation; Neoplasm Metastasis; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Pyrroles; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction; Skin; Skin Neoplasms; Substrate Specificity; Sulfonamides; Sunitinib; Vemurafenib	2013
Sunitinib objective response in metastatic renal cell carcinoma: analysis of 1059 patients treated on clinical trials. European journal of cancer (Oxford, England : 1990), 2014, Volume: 50, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Renal Cell; Clinical Trials as Topic; Drug Administration Schedule; Female; Humans; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Outcome Assessment, Health Care; Proportional Hazards Models; Pyrroles; Retrospective Studies; Sunitinib; Young Adult	2014
Validation of the MSKCC and Heng risk criteria models for predicting survival in patients with metastatic renal cell carcinoma treated with sunitinib. Annals of surgical oncology, 2013, Volume: 20, Issue:13 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Papillary; Carcinoma, Renal Cell; Female; Follow-Up Studies; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Grading; Neoplasm Metastasis; Nomograms; Prognosis; Pyrroles; Retrospective Studies; Risk Factors; Sunitinib; Survival Rate	2013
Sunitinib-induced severe hypoglycemia in a diabetic patient. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2014, Volume: 20, Issue:6 Topics: Antineoplastic Agents; Blood Glucose; Carcinoma, Renal Cell; Diabetes Mellitus, Type 2; Humans; Hypoglycemia; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Severity of Illness Index; Sunitinib	2014
Management of adverse events in patients with metastatic renal cell carcinoma treated with sunitinib and clinical outcomes. Anticancer research, 2013, Volume: 33, Issue:11 Topics: Aged; Blood Pressure Determination; Carcinoma, Renal Cell; Disease Management; Female; Follow-Up Studies; Humans; Hypertension; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Patient Compliance; Prognosis; Pyrroles; Sunitinib	2013
Active smoking may negatively affect response rate, progression-free survival, and overall survival of patients with metastatic renal cell carcinoma treated with sunitinib. The oncologist, 2014, Volume: 19, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Multicenter Studies as Topic; Multivariate Analysis; Neoplasm Metastasis; Pyrroles; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Smoking; Sunitinib; Treatment Outcome; Young Adult	2014
Clinical and laboratory prognostic factors in patients with metastatic renal cell carcinoma treated with sunitinib and sorafenib after progression on cytokines. Urologic oncology, 2014, Volume: 32, Issue:4 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Cytokines; Disease Progression; Female; Follow-Up Studies; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Niacinamide; Phenylurea Compounds; Prognosis; Pyrroles; Retrospective Studies; Sorafenib; Sunitinib; Survival Rate	2014
Nephrogenic epistaxis. Singapore medical journal, 2014, Volume: 55, Issue:7 Topics: Adult; Carcinoma, Renal Cell; Chemoradiotherapy; Diagnosis, Differential; Epistaxis; Humans; Indoles; Kidney Diseases; Male; Neoplasm Metastasis; Nose; Nose Neoplasms; Positron-Emission Tomography; Pyrroles; Recurrence; Sunitinib; Tomography, X-Ray Computed	2014
Identification of tissue microRNAs predictive of sunitinib activity in patients with metastatic renal cell carcinoma. PloS one, 2014, Volume: 9, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Humans; Indoles; Kidney Neoplasms; Male; Matrix Metalloproteinase 9; MicroRNAs; Middle Aged; Models, Biological; Neoplasm Metastasis; Paracrine Communication; Prognosis; Pyrroles; Reproducibility of Results; Sunitinib; Treatment Outcome; Vascular Endothelial Growth Factor A	2014
Clinical outcome of Turkish metastatic breast cancer patients with currently available treatment modalities--single center experience. Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Disease-Free Survival; Female; Follow-Up Studies; Humans; Indoles; Kaplan-Meier Estimate; Lapatinib; Middle Aged; Neoplasm Metastasis; Postmenopause; Premenopause; Pyrroles; Quinazolines; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Sunitinib; Survival Rate; Trastuzumab; Turkey; Young Adult	2014
[Systemic treatment of metastatic renal cell carcinoma: change of paradigms after introduction of targeted therapy]. Der Urologe. Ausg. A, 2014, Volume: 53, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Combined Modality Therapy; Female; Humans; Immunotherapy; Indoles; Kidney Neoplasms; Male; Middle Aged; Molecular Targeted Therapy; Neoplasm Metastasis; Neoplasm Staging; Nephrectomy; Niacinamide; Phenylurea Compounds; Pyrroles; Retrospective Studies; Sorafenib; Sunitinib; Survival Rate	2014
A 2 weeks on and 1 week off schedule of sunitinib is associated with decreased toxicity in metastatic renal cell carcinoma. European journal of cancer (Oxford, England : 1990), 2014, Volume: 50, Issue:6 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Drug Administration Schedule; Fatigue; Female; Hand-Foot Syndrome; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Retrospective Studies; Sunitinib; Treatment Outcome	2014
Tumor genetic analyses of patients with metastatic renal cell carcinoma and extended benefit from mTOR inhibitor therapy. Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Apr-01, Volume: 20, Issue:7 Topics: Aged; Carcinoma, Renal Cell; Exome; Genome, Human; Humans; Indoles; Male; Middle Aged; Neoplasm Metastasis; Protein Kinase Inhibitors; Pyrroles; Signal Transduction; Sunitinib; TOR Serine-Threonine Kinases; Tuberous Sclerosis Complex 1 Protein; Tumor Suppressor Proteins	2014
The relevance of testing the efficacy of anti-angiogenesis treatments on cells derived from primary tumors: a new method for the personalized treatment of renal cell carcinoma. PloS one, 2014, Volume: 9, Issue:3 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Carcinoma, Renal Cell; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gene Expression; Humans; Indoles; Kidney Neoplasms; Mice; Molecular Targeted Therapy; Neoplasm Metastasis; Neoplasm Staging; Neovascularization, Pathologic; Niacinamide; Phenylurea Compounds; Precision Medicine; Pyrroles; Receptor Protein-Tyrosine Kinases; Sorafenib; Sunitinib; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2014
Significance of circulating matrix metalloproteinase-9 to tissue inhibitor of metalloproteinases-2 ratio as a predictor of disease progression in patients with metastatic renal cell carcinoma receiving sunitinib. Urologic oncology, 2014, Volume: 32, Issue:5 Topics: Adult; Aged; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Renal Cell; Disease Progression; Enzyme-Linked Immunosorbent Assay; Female; Humans; Indoles; Kidney Neoplasms; Male; Matrix Metalloproteinase 9; Middle Aged; Neoplasm Metastasis; Pyrroles; Retrospective Studies; Sunitinib; Tissue Inhibitor of Metalloproteinase-2; Treatment Outcome	2014
Superior vena caval syndrome secondary to metastatic renal cell carcinoma. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2014, Volume: 24 Suppl 1 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Fatal Outcome; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Nephrectomy; Pulmonary Embolism; Pyrroles; Radiotherapy; Sunitinib; Superior Vena Cava Syndrome	2014
Prognostic significance of cytoreductive nephrectomy in patients with synchronous metastases from renal cell carcinoma treated with first-line sunitinib: a European multiinstitutional study. Clinical genitourinary cancer, 2014, Volume: 12, Issue:5 Topics: Aged; Antineoplastic Agents; Bone Neoplasms; Brain Neoplasms; Carcinoma, Renal Cell; Cytoreduction Surgical Procedures; Disease-Free Survival; Europe; Female; Humans; Indoles; Kidney Neoplasms; Male; Neoplasm Metastasis; Nephrectomy; Protein Kinase Inhibitors; Pyrroles; Retrospective Studies; Sunitinib; Treatment Outcome; Vascular Endothelial Growth Factor A	2014
[The safety and efficacy of sunitinib using a modified regimen (2 weeks on/1 week off) for treatment of metastatic renal cell carcinoma]. Hinyokika kiyo. Acta urologica Japonica, 2014, Volume: 60, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Drug Administration Schedule; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Prospective Studies; Pyrroles; Sunitinib	2014
Volumetric FDG-PET predicts overall and progression- free survival after 14 days of targeted therapy in metastatic renal cell carcinoma. BMC cancer, 2014, Jun-06, Volume: 14 Topics: Aged; Carcinoma, Renal Cell; Cone-Beam Computed Tomography; Disease-Free Survival; Female; Fluorodeoxyglucose F18; Humans; Indazoles; Indoles; Kaplan-Meier Estimate; Male; Middle Aged; Molecular Targeted Therapy; Neoplasm Metastasis; Positron-Emission Tomography; Prognosis; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Sulfonamides; Sunitinib; Treatment Outcome	2014
Hypothyroidism as a predictive clinical marker of better treatment response to sunitinib therapy. Anticancer research, 2014, Volume: 34, Issue:6 Topics: Aged; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Renal Cell; Cohort Studies; Female; Follow-Up Studies; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Male; Neoplasm Metastasis; Neoplasm Staging; Pyrroles; Sunitinib; Survival Rate; Treatment Outcome	2014
Blocking lipid synthesis overcomes tumor regrowth and metastasis after antiangiogenic therapy withdrawal. Cell metabolism, 2014, Aug-05, Volume: 20, Issue:2 Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Disease Progression; Fatty Acid Synthases; Homeodomain Proteins; Humans; Indoles; Lipids; Metabolomics; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Niacinamide; Phenylurea Compounds; Proteomics; Pyrroles; RNA Interference; Sorafenib; Sunitinib; Transplantation, Heterologous	2014
Experience with sunitinib treatment for metastatic renal cell carcinoma in a large cohort of Israeli patients: outcome and associated factors. The Israel Medical Association journal : IMAJ, 2014, Volume: 16, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Cohort Studies; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Indoles; Israel; Kidney Neoplasms; Male; Middle Aged; Multivariate Analysis; Neoplasm Metastasis; Pyrroles; Retrospective Studies; Sunitinib; Survival Rate; Treatment Outcome; Young Adult	2014
The use of sunitinib in renal cell carcinoma: where are we now? Expert review of anticancer therapy, 2014, Volume: 14, Issue:9 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Humans; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Pyrroles; Sunitinib	2014
Expression of TNF-α and CD44 is implicated in poor prognosis, cancer cell invasion, metastasis and resistance to the sunitinib treatment in clear cell renal cell carcinomas. International journal of cancer, 2015, Apr-01, Volume: 136, Issue:7 Topics: Antineoplastic Agents; Cadherins; Carcinoma, Renal Cell; Cell Hypoxia; Cell Movement; Drug Resistance, Neoplasm; Gene Expression; Humans; Hyaluronan Receptors; Immunohistochemistry; Indoles; Kidney Neoplasms; Neoplasm Grading; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Staging; Prognosis; Pyrroles; Sunitinib; Tumor Necrosis Factor-alpha	2015
Imatinib escalation or sunitinib treatment after first-line imatinib in metastatic gastrointestinal stromal tumor patients. Anticancer research, 2014, Volume: 34, Issue:9 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Benzamides; Drug Substitution; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Mutation; Neoplasm Metastasis; Piperazines; Prognosis; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Retreatment; Sunitinib; Treatment Outcome; Young Adult	2014
Second-line sunitinib as a feasible approach for iodine-refractory differentiated thyroid cancer after the failure of first-line sorafenib. Endocrine, 2015, Volume: 49, Issue:3 Topics: Antineoplastic Agents; Disease Progression; Drug Resistance, Neoplasm; Female; Humans; Indoles; Iodine Radioisotopes; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Pyrroles; Sorafenib; Sunitinib; Thyroid Neoplasms; Treatment Failure	2015
Neoadjuvant antiangiogenic therapy reveals contrasts in primary and metastatic tumor efficacy. EMBO molecular medicine, 2014, Volume: 6, Issue:12 Topics: Angiogenesis Inhibitors; Animals; Humans; Indoles; Mice; Mice, SCID; Neoadjuvant Therapy; Neoplasm Metastasis; Neoplasms; Pyrroles; Sunitinib; Treatment Outcome; Vascular Endothelial Growth Factor A	2014
Assessing metastasis risk after pre-operative anti-angiogenic therapy. EMBO molecular medicine, 2014, Volume: 6, Issue:12 Topics: Angiogenesis Inhibitors; Animals; Humans; Indoles; Neoadjuvant Therapy; Neoplasm Metastasis; Neoplasms; Pyrroles	2014
Hyperlipidemia and hypothyroidism among metastatic renal cell carcinoma patients taking sunitinib malate. Related or unrelated adverse events? Clinical genitourinary cancer, 2015, Volume: 13, Issue:2 Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Cholesterol; Female; Humans; Hyperlipidemias; Hypothyroidism; Incidence; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Prospective Studies; Pyrroles; Sunitinib; Triglycerides	2015
Association of drug exposure with toxicity and clinical response in metastatic renal cell carcinoma patients receiving an attenuated dosing regimen of sunitinib. Targeted oncology, 2015, Volume: 10, Issue:3 Topics: Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Disease Progression; Drug Administration Schedule; Drug Monitoring; Female; Humans; Indoles; Kidney Neoplasms; Longitudinal Studies; Male; Middle Aged; Mucositis; Neoplasm Metastasis; Prospective Studies; Pyrroles; Singapore; Sunitinib	2015
Health economic changes as a result of implementation of targeted therapy for metastatic renal cell carcinoma: national results from DARENCA study 2. European urology, 2015, Volume: 68, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care; Angiogenesis Inhibitors; Antineoplastic Agents; Bevacizumab; Carcinoma, Renal Cell; Costs and Cost Analysis; Denmark; Drug Costs; Efficiency; Employment; Everolimus; Female; Fluorouracil; Health Care Costs; Hospitalization; Humans; Immunologic Factors; Indoles; Interferon-alpha; Interleukin-2; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyrroles; Radiography; Radiotherapy; Registries; Sirolimus; Sorafenib; Sunitinib	2015
Efficacy of sunitinib in patients with metastatic or unresectable renal cell carcinoma and renal insufficiency. European journal of cancer (Oxford, England : 1990), 2015, Volume: 51, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Female; Glomerular Filtration Rate; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Renal Insufficiency; Retrospective Studies; Sunitinib	2015
Angiotensin system inhibitors and survival outcomes in patients with metastatic renal cell carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, Jun-01, Volume: 21, Issue:11 Topics: Adult; Aged; Angiotensins; Carcinoma, Renal Cell; Clinical Trials as Topic; Disease-Free Survival; Female; Humans; Indoles; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Metastasis; Prognosis; Pyrroles; Renin-Angiotensin System; Sirolimus; Sunitinib; Treatment Outcome	2015
Sunitinib dosing schedule 2/1 improves tolerability, efficacy, and health-related quality of life in Chinese patients with metastatic renal cell carcinoma. Urologic oncology, 2015, Volume: 33, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Asian People; Carcinoma, Renal Cell; Drug Administration Schedule; Female; Humans; Indoles; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Quality of Life; Sunitinib; Treatment Outcome	2015
Comparison of Two Prognostic Models in Patients with Metastatic Renal Cancer Treated with Sunitinib: a Retrospective, Registry-Based Study. Targeted oncology, 2015, Volume: 10, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Models, Statistical; Neoplasm Metastasis; Prognosis; Pyrroles; Registries; Retrospective Studies; Sunitinib; Treatment Outcome	2015
Stimulus-dependent differences in signalling regulate epithelial-mesenchymal plasticity and change the effects of drugs in breast cancer cell lines. Cell communication and signaling : CCS, 2015, May-15, Volume: 13 Topics: Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Epidermal Growth Factor; Epithelial-Mesenchymal Transition; Everolimus; Female; Humans; Immunosuppressive Agents; Neoplasm Metastasis; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases	2015
A case of metastatic renal cell carcinoma and bile duct carcinoma treated with a combination of sunitinib and gemcitabine. BMC cancer, 2015, May-22, Volume: 15 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Carcinoma, Renal Cell; Cholangiopancreatography, Magnetic Resonance; Deoxycytidine; Female; Gemcitabine; Humans; Indoles; Kidney Neoplasms; Lung Neoplasms; Neoplasm Metastasis; Neoplasms, Second Primary; Polymorphism, Single Nucleotide; Pyrroles; Sunitinib; Tomography, X-Ray Computed; Treatment Outcome	2015
Sunitinib Treatment Exacerbates Intratumoral Heterogeneity in Metastatic Renal Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, Sep-15, Volume: 21, Issue:18 Topics: Aged; Antineoplastic Agents; Biomarkers; Carcinoma, Renal Cell; Clinical Trials, Phase II as Topic; Cluster Analysis; Comparative Genomic Hybridization; DNA-Binding Proteins; Drug Design; Female; Gene Expression Profiling; Genotype; Humans; Hypoxia; Indoles; Kidney Neoplasms; Male; Middle Aged; Mutation; Neoplasm Metastasis; Nephrectomy; Nuclear Proteins; Pilot Projects; Protein Array Analysis; Protein Kinase Inhibitors; Pyrroles; RNA, Messenger; Sunitinib; Transcription Factors; Von Hippel-Lindau Tumor Suppressor Protein	2015
miR-155 and miR-484 Are Associated with Time to Progression in Metastatic Renal Cell Carcinoma Treated with Sunitinib. BioMed research international, 2015, Volume: 2015 Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Renal Cell; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Indoles; Kaplan-Meier Estimate; Male; MicroRNAs; Middle Aged; Neoplasm Metastasis; Neovascularization, Pathologic; Pyrroles; Sunitinib	2015
Final results from the large sunitinib global expanded-access trial in metastatic renal cell carcinoma. British journal of cancer, 2015, Jun-30, Volume: 113, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Sunitinib; Young Adult	2015
Sunitinib pretreatment improves tumor-infiltrating lymphocyte expansion by reduction in intratumoral content of myeloid-derived suppressor cells in human renal cell carcinoma. Cancer immunology, immunotherapy : CII, 2015, Volume: 64, Issue:10 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Everolimus; Female; Humans; Immunotherapy; Indazoles; Indoles; Interleukin-2; Kidney Neoplasms; Lymphocytes, Tumor-Infiltrating; Male; Middle Aged; Molecular Targeted Therapy; Myeloid Cells; Neoplasm Metastasis; Programmed Cell Death 1 Receptor; Pyrimidines; Pyrroles; Sirolimus; Sulfonamides; Sunitinib; T-Lymphocytes; Treatment Outcome	2015
Invasiveness and metastasis of retinoblastoma in an orthotopic zebrafish tumor model. Scientific reports, 2015, Jul-14, Volume: 5 Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Heterografts; Humans; Indoles; Mice; Morpholinos; Neoplasm Invasiveness; Neoplasm Metastasis; Neovascularization, Pathologic; Pyrroles; Retinoblastoma; Sunitinib; Vascular Endothelial Growth Factor A; Zebrafish	2015
Circulating Plasma Biomarkers for TSU-68, an Oral Antiangiogenic Agent, in Patients with Metastatic Breast Cancer. Cancer research and treatment, 2016, Volume: 48, Issue:2 Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; C-Reactive Protein; Docetaxel; Enzyme-Linked Immunosorbent Assay; Female; Fibroblast Growth Factors; Humans; Indoles; Interleukin-6; Middle Aged; Neoplasm Metastasis; Oxindoles; Propionates; Pyrroles; Taxoids; Vascular Endothelial Growth Factor A	2016
Association of ABCB1 and FLT3 Polymorphisms with Toxicities and Survival in Asian Patients Receiving Sunitinib for Renal Cell Carcinoma. PloS one, 2015, Volume: 10, Issue:8 Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Asian People; ATP Binding Cassette Transporter, Subfamily B; Carcinoma, Renal Cell; Disease-Free Survival; Drug-Related Side Effects and Adverse Reactions; Female; fms-Like Tyrosine Kinase 3; Gene Frequency; Genetic Predisposition to Disease; Genotype; Haplotypes; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Polymorphism, Single Nucleotide; Pyrroles; Singapore; Sunitinib; Treatment Outcome; Young Adult	2015
Is Late Recurrence a Predictive Clinical Marker for Better Sunitinib Response in Metastatic Renal Cell Carcinoma Patients? Clinical genitourinary cancer, 2015, Volume: 13, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prognosis; Pyrroles; Sunitinib; Survival Analysis; Treatment Outcome; Turkey	2015
Early Tumor Shrinkage Under Treatment with First-line Tyrosine Kinase Inhibitors as a Predictor of Overall Survival in Patients with Metastatic Renal Cell Carcinoma: a Retrospective Multi-Institutional Study in Japan. Targeted oncology, 2016, Volume: 11, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Indoles; Japan; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Predictive Value of Tests; Protein Kinase Inhibitors; Pyrroles; Retrospective Studies; Sorafenib; Sunitinib; Treatment Outcome	2016
Association of single nucleotide polymorphisms in IL8 and IL13 with sunitinib-induced toxicity in patients with metastatic renal cell carcinoma. European journal of clinical pharmacology, 2015, Volume: 71, Issue:12 Topics: Aged; Alleles; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Indoles; Interleukin-13; Interleukin-8; Kidney Neoplasms; Logistic Models; Male; Middle Aged; Neoplasm Metastasis; Polymorphism, Single Nucleotide; Pyrroles; Sunitinib; Survival Rate	2015
Safety and efficacy of sunitinib for advanced non-clear cell renal cell carcinoma. Asia-Pacific journal of clinical oncology, 2015, Volume: 11, Issue:4 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Disease Progression; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Nevus, Spindle Cell; Prognosis; Pyrroles; Retrospective Studies; Sunitinib; Survival Rate	2015
Long-term outcomes of tyrosine kinase inhibitor discontinuation in patients with metastatic renal cell carcinoma. Cancer chemotherapy and pharmacology, 2016, Volume: 77, Issue:2 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Disease Progression; Disease-Free Survival; Female; Humans; Indazoles; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Retrospective Studies; Sorafenib; Sulfonamides; Sunitinib; Time Factors; Withholding Treatment	2016
Endoglin targeting inhibits tumor angiogenesis and metastatic spread in breast cancer. Oncogene, 2016, 08-04, Volume: 35, Issue:31 Topics: Animals; Antibodies, Monoclonal; Breast Neoplasms; Endoglin; Female; Humans; Indoles; Neoplasm Metastasis; Neovascularization, Pathologic; Pyrroles; Smad1 Protein; Vascular Endothelial Growth Factor A; Zebrafish	2016
Baseline tumor volume in assessing prognosis of patients with intermediate-risk synchronous metastatic renal cell carcinoma. Urologic oncology, 2016, Volume: 34, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Prognosis; Pyrroles; Retrospective Studies; Sunitinib; Tumor Burden	2016
Lysophosphatidic acid activates Arf6 to promote the mesenchymal malignancy of renal cancer. Nature communications, 2016, Feb-08, Volume: 7 Topics: ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Adult; Aged; Aged, 80 and over; Amides; Animals; Antineoplastic Agents; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Female; GTP-Binding Protein alpha Subunits, G12-G13; Guanine Nucleotide Exchange Factors; HEK293 Cells; Humans; Immunohistochemistry; Indoles; Isoxazoles; Kidney Neoplasms; Lysophospholipids; Male; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Nerve Tissue Proteins; Propionates; Pyridines; Pyrroles; Receptors, Lysophosphatidic Acid; Signal Transduction; Sirolimus; Sunitinib; Triazoles	2016
Role of dose exposure and inflammatory status in a single center, real-world analysis of sunitinib in patients with metastatic renal cell carcinoma. Future oncology (London, England), 2016, Volume: 12, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Cohort Studies; Disease Progression; Female; Humans; Indoles; Inflammation; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Sunitinib; Treatment Outcome	2016
Efficacy and safety of sorafenib versus sunitinib as first-line treatment in patients with metastatic renal cell carcinoma: largest single-center retrospective analysis. Oncotarget, 2016, May-10, Volume: 7, Issue:19 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Diarrhea; Disease-Free Survival; Fatigue; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Pyrroles; Retrospective Studies; Sorafenib; Sunitinib; Treatment Outcome	2016
Lethal acute liver failure in a patient treated with sunitinib. BMJ case reports, 2016, Mar-01, Volume: 2016 Topics: Acute Kidney Injury; Aged; Carcinoma, Renal Cell; Fatal Outcome; Humans; Indoles; Kidney Neoplasms; Liver Failure, Acute; Male; Neoplasm Metastasis; Protein Kinase Inhibitors; Pyrroles; Sunitinib	2016
Evaluation of polymorphisms in angiogenesis-related genes as predictive and prognostic markers for sunitinib-treated metastatic renal cell carcinoma patients. Journal of cancer research and clinical oncology, 2016, Volume: 142, Issue:6 Topics: Aged; Angiogenesis Inhibitors; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neovascularization, Pathologic; Polymorphism, Single Nucleotide; Prognosis; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Sunitinib; Vascular Endothelial Growth Factor A	2016
Circulating Carbonic Anhydrase IX and Antiangiogenic Therapy in Breast Cancer. Disease markers, 2016, Volume: 2016 Topics: Adult; Aged; Angiogenesis Inhibitors; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carbonic Anhydrase IX; Carbonic Anhydrases; Cyclophosphamide; Doxorubicin; Female; Humans; Indoles; Middle Aged; Neoadjuvant Therapy; Neoplasm Metastasis; Paclitaxel; Pyrroles; Sunitinib	2016
Fuhrman Grade and Neutrophil-To-Lymphocyte Ratio Influence on Survival in Patients With Metastatic Renal Cell Carcinoma Treated With First-Line Tyrosine Kinase Inhibitors. Clinical genitourinary cancer, 2016, Volume: 14, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Indazoles; Indoles; Kidney Neoplasms; Leukocyte Count; Lymphocyte Count; Male; Middle Aged; Neoplasm Grading; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Prognosis; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Retrospective Studies; Sorafenib; Sulfonamides; Sunitinib; Survival Analysis; Treatment Outcome; Young Adult	2016
Sarcopenia and the Modified Glasgow Prognostic Score are Significant Predictors of Survival Among Patients with Metastatic Renal Cell Carcinoma Who are Receiving First-Line Sunitinib Treatment. Targeted oncology, 2016, Volume: 11, Issue:5 Topics: Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Indoles; Male; Neoplasm Metastasis; Prognosis; Pyrroles; Retrospective Studies; Sarcopenia; Sunitinib	2016
Impact of Second-Line Targeted Therapy Dose Intensity on Patients With Metastatic Renal Cell Carcinoma. Clinical genitourinary cancer, 2016, Volume: 14, Issue:6 Topics: Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Databases, Factual; Everolimus; Female; Humans; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Retrospective Studies; Sunitinib; Survival Analysis; Treatment Outcome	2016
Metformin Use and Outcome of Sunitinib Treatment in Patients With Diabetes and Metastatic Renal Cell Carcinoma. Clinical genitourinary cancer, 2016, Volume: 14, Issue:5 Topics: Aged; Aged, 80 and over; Carcinoma, Renal Cell; Comorbidity; Diabetes Mellitus; Disease-Free Survival; Female; Humans; Indoles; Kidney Neoplasms; Male; Metformin; Middle Aged; Neoplasm Metastasis; Proportional Hazards Models; Pyrroles; Retrospective Studies; Sunitinib; Treatment Outcome	2016
Prescribing Preferences in the First-Line Treatment for Patients With Metastatic Renal Cell Carcinoma in the United States. Clinical genitourinary cancer, 2016, Volume: 14, Issue:5 Topics: Aged; Carcinoma, Renal Cell; Drug Prescriptions; Female; Humans; Indazoles; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Practice Guidelines as Topic; Practice Patterns, Physicians'; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Sulfonamides; Sunitinib; Survival Analysis; Treatment Outcome; United States	2016
Early Tumour Shrinkage: A Tool for the Detection of Early Clinical Activity in Metastatic Renal Cell Carcinoma. European urology, 2016, Volume: 70, Issue:6 Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Axitinib; Bevacizumab; Bone Neoplasms; Carcinoma, Renal Cell; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Disease-Free Survival; Humans; Imidazoles; Indazoles; Indoles; Interferon-alpha; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Prognosis; Proportional Hazards Models; Pyrroles; Remission Induction; Retrospective Studies; Sirolimus; Sorafenib; Sunitinib; Survival Rate; Treatment Outcome; Tumor Burden	2016
Hypothyroidism and Thyroid Autoimmunity as a Prognostic Biomarker of Better Response in Metastatic Cancer Long-Term Survivors Treated with Sunitinib. Thyroid : official journal of the American Thyroid Association, 2016, Volume: 26, Issue:9 Topics: Aged; Antineoplastic Agents; Biomarkers; Female; Humans; Hypothyroidism; Immunoenzyme Techniques; Indoles; Male; Middle Aged; Neoplasm Metastasis; Prognosis; Pyrroles; Sunitinib; Survivors; Thyroid Neoplasms; Thyroiditis, Autoimmune; Treatment Outcome	2016
Pazopanib versus sunitinib for the treatment of metastatic renal cell carcinoma patients with poor-risk features. Cancer chemotherapy and pharmacology, 2016, Volume: 78, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Female; Follow-Up Studies; Humans; Indazoles; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrimidines; Pyrroles; Retrospective Studies; Risk Factors; Sulfonamides; Sunitinib; Survival Rate; Treatment Outcome; Young Adult	2016
Clinical Experience of Escalated Sunitinib Dose in Select Patients With Metastatic Renal Cell Carcinoma. Clinical genitourinary cancer, 2017, Volume: 15, Issue:1 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Disease Progression; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Retrospective Studies; Sunitinib; Survival Analysis; Treatment Outcome	2017
Metastatic Renal Cell Carcinoma Presenting as Painful Chewing Successfully Treated with Combined Nivolumab and Sunitinib. The Permanente journal, 2016,Summer, Volume: 20, Issue:3 Topics: Aged; Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Humans; Indoles; Kidney Neoplasms; Male; Mastication; Neoplasm Metastasis; Nivolumab; Pain; Pyrroles; Sunitinib; Treatment Outcome; United States	2016
Outcome of Patients With Metastatic Chromophobe Renal Cell Carcinoma Treated With Sunitinib. The oncologist, 2016, Volume: 21, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Retrospective Studies; Sunitinib; Treatment Outcome	2016
Systemic immune-inflammation index predicts the clinical outcome in patients with metastatic renal cell cancer treated with sunitinib. Oncotarget, 2016, 08-23, Volume: 7, Issue:34 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Proportional Hazards Models; Pyrroles; Retrospective Studies; Sunitinib	2016
Effect of Metformin Use on Survival Outcomes in Patients With Metastatic Renal Cell Carcinoma. Clinical genitourinary cancer, 2017, Volume: 15, Issue:2 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Female; Humans; Indoles; Kidney Neoplasms; Male; Metformin; Neoplasm Metastasis; Pyrroles; Retrospective Studies; Sunitinib; Survival Analysis; Treatment Outcome	2017
Model-based prediction of progression-free survival in patients with first-line renal cell carcinoma using week 8 tumor size change from baseline. Cancer chemotherapy and pharmacology, 2016, Volume: 78, Issue:3 Topics: Antineoplastic Agents; Axitinib; Carcinoma, Renal Cell; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Disease-Free Survival; Humans; Imidazoles; Indazoles; Indoles; Interferon-alpha; Kidney Neoplasms; Logistic Models; Multivariate Analysis; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Pyrroles; Randomized Controlled Trials as Topic; Sorafenib; Sunitinib; Time Factors	2016
A retrospective study of predictive factors for unexpectedly prolonged or shortened progression-free survival and overall survival among patients with metastatic renal cell carcinoma who received first-line targeted therapy. BMC cancer, 2016, 08-02, Volume: 16 Topics: Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Indazoles; Indoles; Kidney Neoplasms; Male; Middle Aged; Molecular Targeted Therapy; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Prognosis; Pyrimidines; Pyrroles; Retrospective Studies; Sirolimus; Sorafenib; Sulfonamides; Sunitinib; Survival Analysis; Treatment Outcome	2016
Utilization of Sunitinib for Renal Cell Cancer: an Egyptian University hospital experience. Asian Pacific journal of cancer prevention : APJCP, 2016, Volume: 17, Issue:7 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Papillary; Carcinoma, Renal Cell; Egypt; Female; Follow-Up Studies; Hospitals, University; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Grading; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Staging; Prognosis; Pyrroles; Sunitinib; Survival Rate; Young Adult	2016
Changes in metabolic profile, iron and ferritin levels during the treatment of metastatic renal cancer - A new potential biomarker? Medical hypotheses, 2016, Volume: 94 Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Renal Cell; Cholesterol; Ferritins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertriglyceridemia; Hypothyroidism; Indazoles; Indoles; Iron; Kidney Neoplasms; Lipids; Metabolome; Models, Theoretical; Neoplasm Metastasis; Prognosis; Pyrimidines; Pyrroles; Sirolimus; Sulfonamides; Sunitinib; TOR Serine-Threonine Kinases; Triglycerides	2016
Fludioxonil induced the cancer growth and metastasis via altering epithelial-mesenchymal transition via an estrogen receptor-dependent pathway in cellular and xenografted breast cancer models. Environmental toxicology, 2017, Volume: 32, Issue:4 Topics: Animals; Antigens, CD; Antineoplastic Agents; Breast Neoplasms; Cadherins; Cathepsin D; Cell Movement; Cell Proliferation; Cell Shape; Cyclin D1; Dioxoles; Epithelial-Mesenchymal Transition; Female; Humans; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Pyrroles; Receptors, Estrogen; Signal Transduction; Tumor Burden; Xenograft Model Antitumor Assays	2017
Efficacy of Sunitinib in Elderly Patients with Metastatic Renal Cell Carcinoma: Data from Real-World Clinical Practice. Drugs & aging, 2016, Volume: 33, Issue:9 Topics: Age Factors; Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Czech Republic; Disease Progression; Disease-Free Survival; Dose-Response Relationship, Drug; Humans; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Pyrroles; Registries; Retrospective Studies; Sunitinib; Time-to-Treatment	2016
Clinical effects of single nucleotide polymorphisms on drug-related genes in Japanese metastatic renal cell carcinoma patients treated with sunitinib. Anti-cancer drugs, 2017, Volume: 28, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Asian People; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Polymorphism, Single Nucleotide; Pyrroles; Sunitinib	2017
Discontinuation of anti-VEGF cancer therapy promotes metastasis through a liver revascularization mechanism. Nature communications, 2016, 09-01, Volume: 7 Topics: Angiogenesis Inhibitors; Animals; Female; Humans; Indoles; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplasm Metastasis; Neoplasms; Pyrroles; Sunitinib; Vascular Endothelial Growth Factor A	2016
Clinical Effect of Dose Escalation After Disease Progression in Patients With Metastatic Renal Cell Carcinoma. Clinical genitourinary cancer, 2017, Volume: 15, Issue:2 Topics: Adult; Aged; Antineoplastic Agents; Axitinib; Carcinoma, Renal Cell; Disease Progression; Dose-Response Relationship, Drug; Female; Humans; Imidazoles; Indazoles; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Retrospective Studies; Sulfonamides; Sunitinib; Survival Analysis; Treatment Outcome; Tumor Burden	2017
[Relationship between treatment-related hypertension and therapeutic efficacy of vascular endothelial growth factor receptor tyrosine kinase inhibitors in metastatic renal cell carcinoma]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 2016, Sep-23, Volume: 38, Issue:9 Topics: Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Hypertension; Indazoles; Indoles; Kidney Neoplasms; Male; Neoplasm Metastasis; Nephrectomy; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Retrospective Studies; Sulfonamides; Sunitinib; Vascular Endothelial Growth Factor A	2016
Dual energy CT allows for improved characterization of response to antiangiogenic treatment in patients with metastatic renal cell cancer. European radiology, 2017, Volume: 27, Issue:6 Topics: Aged; Angiogenesis Inhibitors; Carcinoma, Renal Cell; Contrast Media; Female; Humans; Indoles; Iodine; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Prospective Studies; Protein-Tyrosine Kinases; Pyrroles; Sunitinib; Tomography, X-Ray Computed; Treatment Outcome	2017
Prognostic role of the cumulative toxicity in patients affected by metastatic renal cells carcinoma and treated with first-line tyrosine kinase inhibitors. Anti-cancer drugs, 2017, Volume: 28, Issue:2 Topics: Aged; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Indazoles; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Prognosis; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Sulfonamides; Sunitinib; Survival Rate	2017
Clinical significance of sunitinib-associated macrocytosis in metastatic renal cell carcinoma. Cancer medicine, 2016, Volume: 5, Issue:12 Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Carcinoma, Renal Cell; Erythrocyte Indices; Erythrocytes, Abnormal; Female; Hematologic Diseases; Humans; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Male; Neoplasm Metastasis; Neoplasm Staging; Niacinamide; Phenylurea Compounds; Pyrroles; Sorafenib; Sunitinib; Treatment Outcome	2016
Therapy of Treatment-Related Hypertension in Metastatic Renal-Cell Cancer Patients Receiving Sunitinib. Clinical genitourinary cancer, 2017, Volume: 15, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Calcium Channel Blockers; Carcinoma, Renal Cell; Female; Humans; Hypertension; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Retrospective Studies; Sunitinib; Treatment Outcome	2017
Tumour response in metastatic renal cell carcinoma treated with tyrosine kinase inhibitors - assessment of intra-tumour heterogeneity. BMC medicine, 2016, Dec-07, Volume: 14, Issue:1 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Genetic Heterogeneity; Humans; Indazoles; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Pharmacogenomic Testing; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Response Evaluation Criteria in Solid Tumors; Sulfonamides; Sunitinib	2016
Sunitinib Treatment Enhances Metastasis of Innately Drug-Resistant Breast Tumors. Cancer research, 2017, 02-15, Volume: 77, Issue:4 Topics: Angiogenesis Inhibitors; Animals; Aquaporin 1; Breast Neoplasms; Carrier Proteins; Cell Movement; Cytokines; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Humans; Indoles; Luminescent Measurements; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Pyrroles; Real-Time Polymerase Chain Reaction; Sunitinib	2017
Mixed Results for Sunitinib in Renal Cancer. Cancer discovery, 2017, Volume: 7, Issue:1 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Chemotherapy, Adjuvant; Clinical Trials as Topic; Disease-Free Survival; Humans; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Neoplasm Staging; Pyrroles; Sunitinib; Survival Analysis; Treatment Outcome	2017
Surgical management of patients with progressing metastatic gastrointestinal stromal tumors receiving sunitinib treatment: A prospective cohort study. International journal of surgery (London, England), 2017, Volume: 39 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Combined Modality Therapy; Cytoreduction Surgical Procedures; Disease Progression; Disease-Free Survival; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Indoles; Male; Middle Aged; Mutation; Neoplasm Metastasis; Postoperative Complications; Prospective Studies; Pyrroles; Sunitinib; Treatment Outcome; Young Adult	2017
CT texture analysis: a potential tool for prediction of survival in patients with metastatic clear cell carcinoma treated with sunitinib. Cancer imaging : the official publication of the International Cancer Imaging Society, 2017, Jan-23, Volume: 17, Issue:1 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Predictive Value of Tests; Pyrroles; Radiographic Image Enhancement; Sunitinib; Tomography, X-Ray Computed; Treatment Outcome	2017
Prognostic role of N-Acetylgalactosaminyltransferase 10 in metastatic renal cell carcinoma. Oncotarget, 2017, Feb-28, Volume: 8, Issue:9 Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Renal Cell; Female; Follow-Up Studies; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; N-Acetylgalactosaminyltransferases; Neoplasm Grading; Neoplasm Metastasis; Neoplasm Staging; Niacinamide; Phenylurea Compounds; Polypeptide N-acetylgalactosaminyltransferase; Prognosis; Pyrroles; Retrospective Studies; Sorafenib; Sunitinib; Survival Rate	2017
Pretreatment Serum Prealbumin as an Independent Prognostic Indicator in Patients With Metastatic Renal Cell Carcinoma Using Tyrosine Kinase Inhibitors as First-Line Target Therapy. Clinical genitourinary cancer, 2017, Volume: 15, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Prealbumin; Prognosis; Proportional Hazards Models; Protein Kinase Inhibitors; Pyrroles; Retrospective Studies; Serum Albumin, Human; Sorafenib; Sunitinib; Treatment Outcome	2017
Outcomes and Drug Costs of Sunitinib Regimens for Metastatic Renal Cell Carcinoma: A Provincial Population-Based Study. Clinical genitourinary cancer, 2017, Volume: 15, Issue:3 Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Drug Costs; Drug Dosage Calculations; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Prognosis; Pyrroles; Retrospective Studies; Sunitinib; Treatment Outcome	2017
Quality of life on TSU-68: Combination of docetaxel and TSU-68, an oral antiangiogenic agent, in patients with metastatic breast cancer previously treated with anthracycline. Asia-Pacific journal of clinical oncology, 2017, Volume: 13, Issue:6 Topics: Angiogenesis Inhibitors; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Docetaxel; Female; Humans; Indoles; Middle Aged; Neoplasm Metastasis; Oxindoles; Propionates; Pyrroles; Quality of Life; Taxoids	2017
von Hippel-Lindau gene status and response to vascular endothelial growth factor targeted therapy for metastatic clear cell renal cell carcinoma. The Journal of urology, 2008, Volume: 180, Issue:3 Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Axitinib; Benzenesulfonates; Bevacizumab; Carcinoma, Renal Cell; Chi-Square Distribution; DNA Primers; Female; Humans; Imidazoles; Indazoles; Indoles; Kidney Neoplasms; Logistic Models; Male; Middle Aged; Mutation; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Prognosis; Pyridines; Pyrroles; Sorafenib; Sunitinib; Survival Rate; Treatment Outcome; Vascular Endothelial Growth Factor A; von Hippel-Lindau Disease	2008
[Antiangiogenics: new therapeutic standards in metastatic kidney cancer]. Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 2008, Volume: 18 Suppl 4 Topics: Angiogenesis Inhibitors; Benzenesulfonates; Humans; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Pyridines; Pyrroles; Sorafenib; Sunitinib	2008
Economic evaluation of sunitinib malate for the first-line treatment of metastatic renal cell carcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Aug-20, Volume: 26, Issue:24 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Cost-Benefit Analysis; Disease-Free Survival; Drug Costs; Humans; Indoles; Interferon-alpha; Interleukin-2; Kidney Neoplasms; Managed Care Programs; Markov Chains; Models, Economic; Neoplasm Metastasis; Pyrroles; Quality-Adjusted Life Years; Sunitinib; Survival Rate	2008
Cardiac toxicity of sunitinib and sorafenib in patients with metastatic renal cell carcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Nov-10, Volume: 26, Issue:32 Topics: Aged; Aged, 80 and over; Benzenesulfonates; Biomarkers; Carcinoma, Renal Cell; Cardiovascular Diseases; Echocardiography; Electrocardiography; Female; Humans; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Prospective Studies; Protein Kinase Inhibitors; Pyridines; Pyrroles; Risk Factors; Sorafenib; Sunitinib; Time Factors; Treatment Outcome	2008
Editorial comment on: Can tyrosine kinase inhibitors be discontinued in patients with metastatic renal cell carcinoma and a complete response to treatment? A multicentre, retrospective analysis. European urology, 2009, Volume: 55, Issue:6 Topics: Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Chemotherapy, Adjuvant; Female; Follow-Up Studies; Humans; Indoles; Kidney Neoplasms; Male; Neoplasm Metastasis; Neoplasm Staging; Nephrectomy; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrroles; Retrospective Studies; Risk Assessment; Sorafenib; Sunitinib; Survival Analysis; Withholding Treatment	2009
Can tyrosine kinase inhibitors be discontinued in patients with metastatic renal cell carcinoma and a complete response to treatment? A multicentre, retrospective analysis. European urology, 2009, Volume: 55, Issue:6 Topics: Aged; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Chemotherapy, Adjuvant; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Indoles; Kidney Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Nephrectomy; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyridines; Pyrroles; Retrospective Studies; Risk Assessment; Sorafenib; Sunitinib; Survival Analysis; Tomography, X-Ray Computed; Treatment Outcome; Withholding Treatment	2009
Major response to sunitinib (Sutene) in metastatic malignant phyllodes tumor of breast. Investigational new drugs, 2009, Volume: 27, Issue:4 Topics: Antineoplastic Agents; Breast Neoplasms; Combined Modality Therapy; Female; Humans; Indoles; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Phyllodes Tumor; Pyrroles; Sunitinib; Treatment Outcome	2009
[Vascular and renal effects of anti-angiogenic therapy]. Nephrologie & therapeutique, 2008, Volume: 4, Issue:7 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzenesulfonates; Bevacizumab; Colorectal Neoplasms; Glomerular Filtration Rate; Glomerulonephritis; Humans; Indoles; Kidney; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Practice Guidelines as Topic; Proteinuria; Pyridines; Pyrroles; Sorafenib; Sunitinib; Vascular Endothelial Growth Factor A	2008
Pathological activation of KIT in metastatic tumors of acral and mucosal melanomas. International journal of cancer, 2009, Feb-15, Volume: 124, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Humans; Indoles; Male; Melanoma; Middle Aged; Mucous Membrane; Mutation; Neoplasm Metastasis; Phosphorylation; Proto-Oncogene Proteins c-kit; Pyrroles; Skin Neoplasms; Stem Cell Factor; Sunitinib	2009
Metastatic sarcomatoid renal cell carcinoma treated with vascular endothelial growth factor-targeted therapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Jan-10, Volume: 27, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Bevacizumab; Carcinoma, Renal Cell; Drug Delivery Systems; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Pyridines; Pyrroles; Retrospective Studies; Sorafenib; Sunitinib; Treatment Outcome; Vascular Endothelial Growth Factor A	2009
Response of the primary tumor to neoadjuvant sunitinib in patients with advanced renal cell carcinoma. The Journal of urology, 2009, Volume: 181, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Biopsy, Needle; Carcinoma, Renal Cell; Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Immunohistochemistry; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Metastasis; Neoplasm Staging; Nephrectomy; Preoperative Care; Pyrroles; Risk Assessment; Sunitinib; Survival Analysis; Tomography, X-Ray Computed; Treatment Outcome	2009
[Medical treatment of metastatic renal cell carcinoma after the approval and market entry of multitargeted tyrosine kinase inhibitors in Germany]. Aktuelle Urologie, 2009, Volume: 40, Issue:1 Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Clinical Trials, Phase III as Topic; Cohort Studies; Data Interpretation, Statistical; Female; Germany; Humans; Indoles; Kidney Neoplasms; Male; Medical Oncology; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyridines; Pyrroles; Sorafenib; Sunitinib; Surveys and Questionnaires; Time Factors; Urology	2009
[Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma]. Aktuelle Urologie, 2009, Volume: 40, Issue:1 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzenesulfonates; Bevacizumab; Carcinoma, Renal Cell; Chemotherapy, Adjuvant; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Humans; Indoles; Kidney; Kidney Neoplasms; Neoadjuvant Therapy; Neoplasm Metastasis; Nephrectomy; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrroles; Risk Assessment; Risk Factors; Sirolimus; Sorafenib; Sunitinib; Time Factors	2009
Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis. Cancer cell, 2009, Mar-03, Volume: 15, Issue:3 Topics: Angiogenesis Inhibitors; Animals; Humans; Indoles; Mice; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Pyrroles; Sunitinib; Xenograft Model Antitumor Assays	2009
Recommendations from the Spanish Oncology Genitourinary Group for the treatment of metastatic renal cancer. Cancer chemotherapy and pharmacology, 2009, Volume: 63 Suppl 1 Topics: Algorithms; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzenesulfonates; Bevacizumab; Carcinoma; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Everolimus; Humans; Indoles; Kidney Neoplasms; Linear Models; Neoplasm Metastasis; Neoplasm Staging; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Protein Kinases; Pyridines; Pyrroles; Receptor Protein-Tyrosine Kinases; Sirolimus; Sorafenib; Sunitinib; TOR Serine-Threonine Kinases; Vascular Endothelial Growth Factors	2009
Sunitinib prolongs survival in genetically engineered mouse models of multistep lung carcinogenesis. Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:4 Topics: AMP-Activated Protein Kinases; Angiogenesis Inhibitors; Animals; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Disease Models, Animal; Genetic Engineering; Immunohistochemistry; Indoles; Lung Neoplasms; Mice; Mutation; Neoplasm Metastasis; Neovascularization, Pathologic; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins p21(ras); Pyrroles; Sunitinib	2009
Sequential sorafenib and sunitinib for renal cell carcinoma. The Journal of urology, 2009, Volume: 182, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Carcinoma, Renal Cell; Cohort Studies; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Female; Follow-Up Studies; Humans; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Probability; Pyridines; Pyrroles; Retrospective Studies; Risk Assessment; Sorafenib; Sunitinib; Survival Analysis; Treatment Outcome	2009
VEGF inhibition and metastasis: possible implications for antiangiogenic therapy. Cancer biology & therapy, 2009, Volume: 8, Issue:13 Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Benzenesulfonates; Bevacizumab; Disease Models, Animal; Humans; Indoles; Neoplasm Metastasis; Neoplasms; Niacinamide; Phenylurea Compounds; Pyridines; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Sorafenib; Sunitinib; Treatment Outcome; Vascular Endothelial Growth Factor A	2009
Effective therapy for metastatic renal cancer, whither to now. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Aug-01, Volume: 27, Issue:22 Topics: Angiogenesis Inhibitors; Carcinoma, Renal Cell; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Indoles; Interferon-alpha; Kidney Neoplasms; Male; Neoplasm Metastasis; Neoplasm Staging; Probability; Prognosis; Pyrroles; Randomized Controlled Trials as Topic; Risk Assessment; Sunitinib; Survival Analysis; Treatment Outcome	2009
Sunitinib efficacy in the treatment of metastatic skin adnexal carcinomas: report of two patients with hidradenocarcinoma and trichoblastic carcinoma. Journal of the European Academy of Dermatology and Venereology : JEADV, 2010, Volume: 24, Issue:2 Topics: Acrospiroma; Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Indoles; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Skin Neoplasms; Sunitinib; Treatment Outcome	2010
New study sheds light on angiogenesis inhibitors. ONS connect, 2009, Volume: 24, Issue:6 Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Humans; Indoles; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Pyrroles; Sunitinib	2009
Inhibition of epithelial to mesenchymal transition in metastatic prostate cancer cells by the novel proteasome inhibitor, NPI-0052: pivotal roles of Snail repression and RKIP induction. Oncogene, 2009, Oct-08, Volume: 28, Issue:40 Topics: Cell Differentiation; Cell Line, Tumor; Cell Movement; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Lactones; Male; Mesoderm; Neoplasm Invasiveness; Neoplasm Metastasis; NF-kappa B; Phosphatidylethanolamine Binding Protein; Prostatic Neoplasms; Protease Inhibitors; Proteasome Inhibitors; Pyrroles; Snail Family Transcription Factors; Transcription Factors	2009
Neoadjuvant sunitinib facilitates nephron-sparing surgery and avoids long-term dialysis in a patient with metachronous contralateral renal cell carcinoma. Clinical genitourinary cancer, 2009, Volume: 7, Issue:2 Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Carcinoma, Renal Cell; Combined Modality Therapy; Female; Humans; Indoles; Kidney Neoplasms; Middle Aged; Neoplasm Metastasis; Pyrroles; Renal Dialysis; Sunitinib	2009
Effect of the UK postcode lottery on survival of patients with metastatic renal cancer: an audit of outcomes in patients with metastatic renal cancer suitable for treatment with tyrosine kinase inhibitors. Clinical oncology (Royal College of Radiologists (Great Britain)), 2009, Volume: 21, Issue:8 Topics: Angiogenesis Inhibitors; Benzenesulfonates; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney; Kidney Neoplasms; Male; Medical Audit; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrroles; Sorafenib; Sunitinib; Survival Analysis; United Kingdom	2009
Metastatic pancreatic adenocarcinoma and renal cell carcinoma treated with gemcitabine and sunitinib malate. A case report. JOP : Journal of the pancreas, 2009, Sep-04, Volume: 10, Issue:5 Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Deoxycytidine; Gemcitabine; Humans; Indoles; Kidney Neoplasms; Male; Neoplasm Metastasis; Neoplasms, Multiple Primary; Pancreatic Neoplasms; Pyrroles; Sunitinib; Treatment Outcome	2009
Tolerance of sunitinib in dialyzed patients with metastatic renal cell carcinoma. Clinical genitourinary cancer, 2009, Volume: 7, Issue:3 Topics: Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Peritoneal Dialysis; Pyrroles; Renal Dialysis; Sunitinib	2009
A case of adult metastatic Xp11 translocation renal cell carcinoma treated successfully with sunitinib. Clinical genitourinary cancer, 2009, Volume: 7, Issue:3 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Chromosomes, Human, Pair 11; Chromosomes, Human, X; Female; Gene Expression Regulation, Neoplastic; Humans; In Situ Hybridization, Fluorescence; Indoles; Karyotyping; Kidney Neoplasms; Middle Aged; Neoplasm Metastasis; Pyrroles; Sunitinib; Translocation, Genetic	2009
Optimizing the size variation threshold for the CT evaluation of response in metastatic renal cell carcinoma treated with sunitinib. Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:5 Topics: Angiogenesis Inhibitors; Carcinoma, Renal Cell; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cohort Studies; Follow-Up Studies; Humans; Indoles; Kidney Neoplasms; Middle Aged; Multicenter Studies as Topic; Neoplasm Metastasis; Pyrroles; Randomized Controlled Trials as Topic; Retrospective Studies; ROC Curve; Sensitivity and Specificity; Sunitinib; Survival Rate; Tomography, X-Ray Computed; Treatment Outcome	2010
VEGFR TKI 'resistance' or transient clinical insensitivity to VEGFR TKI in metastatic renal cell carcinoma. Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:2 Topics: Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Drug Administration Schedule; Drug Resistance, Neoplasm; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Sorafenib; Sunitinib; Time Factors	2010
CT response assessment combining reduction in both size and arterial phase density correlates with time to progression in metastatic renal cancer patients treated with targeted therapies. Cancer biology & therapy, 2010, Volume: 9, Issue:1 Topics: Antineoplastic Agents; Arteries; Carcinoma, Renal Cell; Disease Progression; Humans; Indoles; Kidney; Kidney Neoplasms; Neoplasm Metastasis; Protein Kinase Inhibitors; Pyrroles; Retrospective Studies; Sunitinib; Tomography, X-Ray Computed; Tumor Burden	2010
Assessing tumor response and detecting recurrence in metastatic renal cell carcinoma on targeted therapy: importance of size and attenuation on contrast-enhanced CT. AJR. American journal of roentgenology, 2010, Volume: 194, Issue:1 Topics: Adult; Aged; Analysis of Variance; Benzenesulfonates; Carcinoma, Renal Cell; Contrast Media; Disease Progression; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Pyridines; Pyrroles; Retrospective Studies; Sensitivity and Specificity; Sorafenib; Sunitinib; Survival Rate; Tomography, X-Ray Computed; Treatment Outcome	2010
Protease-activated receptor-1 (PAR-1) promotes the motility of human melanomas and is associated to their metastatic phenotype. Clinical & experimental metastasis, 2010, Volume: 27, Issue:1 Topics: Animals; Cell Line, Tumor; Cell Movement; Disease Progression; Humans; Melanoma; Mice; Mice, SCID; Neoplasm Metastasis; Pyrroles; Quinazolines; Receptor, PAR-1; Skin Neoplasms	2010
Inhibition of MMP-9 transcription and suppression of tumor metastasis by pyrrole-imidazole polyamide. Cancer science, 2010, Volume: 101, Issue:3 Topics: Animals; Cell Line, Tumor; HeLa Cells; Humans; Imidazoles; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Nylons; Promoter Regions, Genetic; Pyrroles; Transcription, Genetic	2010
Sunitinib and sorafenib in metastatic renal cell carcinoma patients with renal insufficiency. Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:8 Topics: Aged; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Pyridines; Pyrroles; Renal Insufficiency; Sorafenib; Sunitinib	2010
Renal cell carcinoma: complete pathological response in a patient with gastric metastasis of renal cell carcinoma. Anti-cancer drugs, 2010, Volume: 21 Suppl 1 Topics: Adrenalectomy; Aged; Angiogenesis Inhibitors; Carcinoma, Renal Cell; Gastrointestinal Neoplasms; Humans; Indoles; Kidney Neoplasms; Male; Neoplasm Metastasis; Nephrectomy; Protein Kinase Inhibitors; Pyrroles; Radiography; Sunitinib; Treatment Outcome	2010
Metastatic renal cell carcinoma treated with sunitinib: early evaluation of treatment response using dynamic contrast-enhanced ultrasonography. Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, Feb-15, Volume: 16, Issue:4 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Contrast Media; Disease-Free Survival; Female; Humans; Indoles; Kidney Neoplasms; Male; Neoplasm Metastasis; Prognosis; Pyrroles; Sunitinib; Ultrasonography	2010
Plasma N-terminal pro-brain natriuretic peptide as prognostic marker in fatal cardial decompensation with sunitinib malate therapy. Urologia internationalis, 2010, Volume: 84, Issue:1 Topics: Aged; Carcinoma, Renal Cell; Echocardiography; Heart Failure; Humans; Indoles; Kidney Neoplasms; Lung Neoplasms; Male; Natriuretic Peptide, Brain; Neoplasm Metastasis; Prognosis; Pyrroles; Retrospective Studies; Sunitinib; Thrombosis	2010
Regarding: 'Costs of managing adverse events in the treatment of first-line metastatic renal cell carcinoma: bevacizumab in combination with interferon-alpha2a compared with sunitinib'. British journal of cancer, 2010, Mar-30, Volume: 102, Issue:7 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoma, Renal Cell; Drug-Related Side Effects and Adverse Reactions; Health Care Costs; Humans; Indoles; Interferon alpha-2; Interferon-alpha; Kidney Neoplasms; Neoplasm Metastasis; Pyrroles; Recombinant Proteins; Sunitinib	2010
Spontaneous bilateral pneumothorax in metastatic renal cell carcinoma on sunitinib therapy. Cancer chemotherapy and pharmacology, 2010, Volume: 66, Issue:2 Topics: Adult; Antineoplastic Agents; Carcinoma, Renal Cell; Humans; Indoles; Interleukin-2; Kidney Neoplasms; Male; Necrosis; Neoplasm Metastasis; Pneumothorax; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Sunitinib; Tomography, X-Ray Computed	2010
Association of percentage of tumour burden removed with debulking nephrectomy and progression-free survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-targeted therapy. BJU international, 2010, Volume: 106, Issue:9 Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Bevacizumab; Carcinoma, Renal Cell; Combined Modality Therapy; Disease-Free Survival; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Nephrectomy; Niacinamide; Phenylurea Compounds; Pyridines; Pyrroles; Retrospective Studies; Sorafenib; Sunitinib; Treatment Outcome; Tumor Burden; Vascular Endothelial Growth Factor A	2010
Treatment with tyrosine kinase inhibitors for patients with differentiated thyroid cancer: the M. D. Anderson experience. The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzenesulfonates; Disease Progression; Disease-Free Survival; DNA Mutational Analysis; Female; Humans; Indoles; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Off-Label Use; Phenylurea Compounds; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyridines; Pyrroles; Sorafenib; Sunitinib; Survival Analysis; Thyroglobulin; Thyroid Neoplasms; Tomography, X-Ray Computed; Treatment Outcome	2010
Morphology, Attenuation, Size, and Structure (MASS) criteria: assessing response and predicting clinical outcome in metastatic renal cell carcinoma on antiangiogenic targeted therapy. AJR. American journal of roentgenology, 2010, Volume: 194, Issue:6 Topics: Adult; Aged; Angiogenesis Inhibitors; Benzenesulfonates; Carcinoma, Renal Cell; Contrast Media; Disease Progression; Female; Humans; Indoles; Iohexol; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Pyridines; Pyrroles; Retrospective Studies; Sensitivity and Specificity; Sorafenib; Sunitinib; Survival Analysis; Tomography, X-Ray Computed; Treatment Outcome	2010
Soluble isoforms of vascular endothelial growth factor are predictors of response to sunitinib in metastatic renal cell carcinomas. PloS one, 2010, May-19, Volume: 5, Issue:5 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Male; Neoplasm Metastasis; Protein Isoforms; Pyrroles; RNA, Messenger; Solubility; Sunitinib; Treatment Outcome; Vascular Endothelial Growth Factor A	2010
Optimizing the use of sunitinib in metastatic renal cell carcinoma: an update from clinical practice. Cancer investigation, 2010, Volume: 28, Issue:8 Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Asthenia; Carcinoma, Renal Cell; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Tolerance; Fatigue; Humans; Indoles; Kidney Neoplasms; Medical History Taking; Neoplasm Metastasis; Proportional Hazards Models; Pyrroles; Sunitinib	2010
Targeting the Transforming Growth Factor-beta pathway inhibits human basal-like breast cancer metastasis. Molecular cancer, 2010, May-26, Volume: 9 Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Humans; Mice; Mice, Nude; Neoplasm Metastasis; Neovascularization, Pathologic; Pyrazoles; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transforming Growth Factor beta; Xenograft Model Antitumor Assays	2010
Harvesting the low-hanging fruit: kinase inhibitors for therapy of advanced medullary and nonmedullary thyroid cancer. The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:6 Topics: Adenocarcinoma, Follicular; Antineoplastic Agents; Benzenesulfonates; Biomarkers, Tumor; Carcinoma, Medullary; Carcinoma, Papillary; Humans; Indoles; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrroles; Sorafenib; Sunitinib; Thyroid Neoplasms	2010
Sunitinib-induced pseudoprogression after whole-brain radiotherapy for metastatic renal cell carcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Sep-01, Volume: 28, Issue:25 Topics: Adolescent; Adult; Brain Neoplasms; Carcinoma, Renal Cell; Combined Modality Therapy; Female; Humans; Indoles; Neoplasm Metastasis; Pyrroles; Sunitinib	2010
Hematologic toxicity in patients treated with sunitinib for advanced thyroid cancer. Thyroid : official journal of the American Thyroid Association, 2010, Volume: 20, Issue:6 Topics: Adult; Aged; Carcinoma, Medullary; Cell Differentiation; Combined Modality Therapy; Enzyme Inhibitors; Female; Hematopoietic System; Humans; Indoles; Male; Middle Aged; Neoplasm Metastasis; Neutropenia; Pyrroles; Receptor Protein-Tyrosine Kinases; Sunitinib; Thyroid Neoplasms	2010
Sunitinib in metastatic thymic carcinomas: laboratory findings and initial clinical experience. British journal of cancer, 2010, Jul-13, Volume: 103, Issue:2 Topics: Adult; Aged; Antineoplastic Agents; Drug Resistance, Neoplasm; Female; Humans; Indoles; Male; Mutation; Neoplasm Metastasis; Protein Kinase Inhibitors; Pyrroles; Receptor Protein-Tyrosine Kinases; Sunitinib; Thymoma; Thymus Neoplasms	2010
Metronomic gemcitabine in combination with sunitinib inhibits multisite metastasis and increases survival in an orthotopic model of pancreatic cancer. Molecular cancer therapeutics, 2010, Volume: 9, Issue:7 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deoxycytidine; Dose-Response Relationship, Drug; Drug Synergism; Female; Gemcitabine; Humans; Indoles; Inhibitory Concentration 50; Kaplan-Meier Estimate; Luminescent Proteins; Mice; Mice, Nude; Neoplasm Metastasis; Pancreatic Neoplasms; Pyrroles; Red Fluorescent Protein; Sunitinib; Tumor Burden; Xenograft Model Antitumor Assays	2010
Prognostic factors for progression-free and overall survival with sunitinib targeted therapy and with cytokine as first-line therapy in patients with metastatic renal cell carcinoma. Annals of oncology : official journal of the European Society for Medical Oncology, 2011, Volume: 22, Issue:2 Topics: Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Disease Progression; Female; Humans; Indoles; Kidney Neoplasms; Male; Neoplasm Metastasis; Pyrroles; Sunitinib; Survival Analysis	2011
Vascular endothelial growth factor-targeted therapy for the treatment of adult metastatic Xp11.2 translocation renal cell carcinoma. Cancer, 2010, Nov-15, Volume: 116, Issue:22 Topics: Adult; Antineoplastic Agents; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Carcinoma, Renal Cell; Chromosomes, Human, X; Female; Humans; Indoles; Kidney Neoplasms; Male; Neoplasm Metastasis; Pyrroles; Sunitinib; Translocation, Genetic; Treatment Outcome; Vascular Endothelial Growth Factor A	2010
Metastatic collecting duct carcinoma of the kidney responded to sunitinib. International journal of clinical oncology, 2011, Volume: 16, Issue:2 Topics: Bone Neoplasms; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney Neoplasms; Lung Neoplasms; Middle Aged; Neoplasm Metastasis; Protein Kinase Inhibitors; Pyrroles; Ribs; Sunitinib	2011
Renal cell carcinoma: ten years of significant advances. Targeted oncology, 2010, Volume: 5, Issue:2 Topics: Angiogenesis Inhibitors; Biomarkers, Pharmacological; Carcinoma, Renal Cell; Clinical Trials as Topic; Combined Modality Therapy; Drug Discovery; Humans; Immunotherapy; Indoles; Kidney Neoplasms; Medical Oncology; Neoplasm Metastasis; Pyrroles; Sunitinib	2010
Hypothyroidism in patients with renal cell carcinoma: blessing or curse? Cancer, 2011, Feb-01, Volume: 117, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Prognosis; Pyridines; Pyrroles; Sorafenib; Sunitinib; Thyrotropin; Treatment Outcome	2011
Comment on 'costs of managing adverse events in the treatment of first-line metastatic renal cell carcinoma: bevacizumab in combination with interferon-α2a compared with sunitinib'. British journal of cancer, 2010, Oct-12, Volume: 103, Issue:8 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoma, Renal Cell; Drug-Related Side Effects and Adverse Reactions; Health Care Costs; Humans; Indoles; Interferon alpha-2; Interferon-alpha; Kidney Neoplasms; Neoadjuvant Therapy; Neoplasm Metastasis; Pyrroles; Recombinant Proteins; Sunitinib; United Kingdom	2010
Increased haematopoietic progenitor cells are associated with poor outcome in patients with metastatic renal cancer treated with sunitinib. Annals of oncology : official journal of the European Society for Medical Oncology, 2011, Volume: 22, Issue:4 Topics: Adult; Aged; Antineoplastic Agents; Biomarkers, Tumor; Cell Proliferation; Disease-Free Survival; Female; Hematopoietic Stem Cells; Humans; Indoles; Insulin-Like Growth Factor I; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Sunitinib; Treatment Outcome	2011
The impact of tumor burden characteristics in patients with metastatic renal cell carcinoma treated with sunitinib. Cancer, 2011, Mar-15, Volume: 117, Issue:6 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Disease Progression; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Retrospective Studies; Sunitinib; Treatment Outcome; Tumor Burden; Young Adult	2011
Feasibility and activity of sorafenib and sunitinib in advanced penile cancer: a preliminary report. Urologia internationalis, 2010, Volume: 85, Issue:3 Topics: Adult; Antigens, CD34; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Squamous Cell; Humans; Immunohistochemistry; Indoles; Ki-67 Antigen; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Penile Neoplasms; Phenylurea Compounds; Positron-Emission Tomography; Pyridines; Pyrroles; Sorafenib; Sunitinib; Tomography, X-Ray Computed; Treatment Outcome	2010
Management of a new isolated metastasis during sunitinib treatment in renal cell carcinoma patients: a lesson from two cases. Urologia internationalis, 2011, Volume: 86, Issue:2 Topics: Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Combined Modality Therapy; Humans; Indoles; Kidney Neoplasms; Lymphatic Metastasis; Magnetic Resonance Imaging; Male; Medical Oncology; Neoplasm Metastasis; Palliative Care; Pyrroles; Radiation-Sensitizing Agents; Sunitinib; Tomography, X-Ray Computed; Treatment Outcome; Vascular Endothelial Growth Factor A	2011
Cyclooxygenase-2 expression in gastrointestinal stromal tumours. Asian Pacific journal of cancer prevention : APJCP, 2010, Volume: 11, Issue:4 Topics: Adult; Aged; Antineoplastic Agents; Benzamides; Chi-Square Distribution; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Progression; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Immunohistochemistry; Indoles; Male; Middle Aged; Mitosis; Neoplasm Metastasis; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Retrospective Studies; Sunitinib; Survival Rate; Tumor Burden	2010
Blue toe syndrome and sunitinib. International journal of clinical oncology, 2011, Volume: 16, Issue:5 Topics: Antineoplastic Agents; Blue Toe Syndrome; Carcinoma, Renal Cell; Heparin, Low-Molecular-Weight; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Protein Kinase Inhibitors; Pyrroles; Sunitinib	2011
The incidence and mechanism of sunitinib-induced thyroid atrophy in patients with metastatic renal cell carcinoma. British journal of cancer, 2011, Jan-18, Volume: 104, Issue:2 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Cohort Studies; Female; Humans; Indoles; Kidney Neoplasms; Male; Neoplasm Metastasis; Pyrroles; Sunitinib; Thyroid Function Tests; Thyroid Gland; Tomography, X-Ray Computed	2011
Biomarker response on exposure to sunitinib and its primary metabolite (SU12662) in metastatic colorectal cancer patients. International journal of clinical pharmacology and therapeutics, 2011, Volume: 49, Issue:1 Topics: Adult; Aged; Biomarkers, Tumor; Colorectal Neoplasms; Female; Humans; Indoles; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Sunitinib; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Vascular Endothelial Growth Factor Receptor-3	2011
Sequential treatment with sorafenib and sunitinib in metastatic renal cell carcinoma: clinical outcomes from a retrospective clinical study. Medical oncology (Northwood, London, England), 2012, Volume: 29, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Carcinoma, Renal Cell; Disease Progression; Female; Follow-Up Studies; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Niacinamide; Phenylurea Compounds; Prognosis; Pyridines; Pyrroles; Retrospective Studies; Sorafenib; Sunitinib; Survival Rate; Time Factors	2012
MDSC as a mechanism of tumor escape from sunitinib mediated anti-angiogenic therapy. International immunopharmacology, 2011, Volume: 11, Issue:7 Topics: Angiogenesis Inhibitors; Animals; Antigens, Ly; Carcinoma, Renal Cell; CD11b Antigen; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Immunosuppression Therapy; Indoles; Kidney Neoplasms; Mice; Mice, Inbred BALB C; Myeloid Cells; Neoadjuvant Therapy; Neoplasm Metastasis; Pyrroles; Sunitinib; Tumor Burden; Tumor Escape	2011
A 51-year-old man with rapidly progressive metastatic sarcomatoid renal cell carcinoma: an apparent complete clinical response to second-line therapy with sunitinib and low-dose interferon-alpha. Clinical advances in hematology & oncology : H&O, 2011, Volume: 9, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Disease Progression; Humans; Indoles; Interferon-alpha; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Sunitinib; Ventricular Function, Left	2011
Mutational spectrum and therapy response of metastasized GIST in Central Switzerland - a population-based study. European journal of cancer (Oxford, England : 1990), 2011, Volume: 47, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Base Sequence; Benzamides; Disease Progression; DNA Mutational Analysis; DNA Primers; Exons; Female; Gastrointestinal Stromal Tumors; Genetics, Population; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Molecular Sequence Data; Mutation; Neoplasm Metastasis; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Retrospective Studies; Sunitinib; Switzerland	2011
Surgical intervention for imatinib and sunitinib-resistant gastrointestinal stromal tumors. International journal of clinical oncology, 2011, Volume: 16, Issue:6 Topics: Aged; Antineoplastic Agents; Benzamides; Drug Resistance, Neoplasm; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Hepatectomy; Humans; Imatinib Mesylate; Indoles; Liver Neoplasms; Male; Mutation; Neoplasm Metastasis; Neoplasm Recurrence, Local; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Radiography; Sunitinib	2011
Safety and treatment patterns of multikinase inhibitors in patients with metastatic renal cell carcinoma at a tertiary oncology center in Italy. BMC cancer, 2011, Mar-24, Volume: 11 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Carcinoma; Fatigue; Female; Humans; Indoles; Italy; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Oncology Service, Hospital; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrroles; Sorafenib; Sunitinib; Treatment Outcome	2011
Expression level of vascular endothelial growth factor receptor-2 in radical nephrectomy specimens as a prognostic predictor in patients with metastatic renal cell carcinoma treated with sunitinib. Urologic oncology, 2013, Volume: 31, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Renal Cell; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Immunoenzyme Techniques; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Grading; Neoplasm Metastasis; Neoplasm Staging; Nephrectomy; Prognosis; Pyrroles; Sunitinib; Survival Rate; Vascular Endothelial Growth Factor Receptor-2	2013
Safety and treatment patterns of angiogenesis inhibitors in patients with metastatic renal cell carcinoma: evidence from US community oncology clinics. Medical oncology (Northwood, London, England), 2012, Volume: 29, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Benzenesulfonates; Cancer Care Facilities; Carcinoma, Renal Cell; Community Health Services; Female; Follow-Up Studies; Humans; Indoles; Kidney Neoplasms; Male; Medical Records; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Niacinamide; Outcome Assessment, Health Care; Phenylurea Compounds; Practice Patterns, Physicians'; Pyridines; Pyrroles; Retrospective Studies; Sorafenib; Sunitinib; United States	2012
Dynamic microbubble contrast-enhanced US to measure tumor response to targeted therapy: a proposed clinical protocol with results from renal cell carcinoma patients receiving antiangiogenic therapy. Radiology, 2011, Volume: 260, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Area Under Curve; Carcinoma, Renal Cell; Contrast Media; Evidence-Based Medicine; Female; Fluorocarbons; Humans; Indoles; Kidney Neoplasms; Male; Microbubbles; Middle Aged; Neoplasm Metastasis; Pyrroles; Reproducibility of Results; Statistics, Nonparametric; Sunitinib; Survival Analysis; Tomography, X-Ray Computed; Ultrasonography	2011
Angiotensin system inhibitors and outcome of sunitinib treatment in patients with metastatic renal cell carcinoma: a retrospective examination. European journal of cancer (Oxford, England : 1990), 2011, Volume: 47, Issue:13 Topics: Aged; Angiogenesis Inhibitors; Angiotensins; Carcinoma, Renal Cell; Cohort Studies; Disease-Free Survival; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Prognosis; Pyrroles; Renin-Angiotensin System; Retrospective Studies; Sunitinib; Treatment Outcome	2011
Efficacy of temsirolimus after previous treatment with sunitinib, sorafenib or everolimus in advanced renal cell cancer. Oncology, 2011, Volume: 80, Issue:1-2 Topics: Aged; Aged, 80 and over; Anemia; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Carcinoma, Renal Cell; Diarrhea; Disease-Free Survival; Everolimus; Female; Humans; Indoles; Karnofsky Performance Status; Kidney Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Nausea; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Pyridines; Pyrroles; Retrospective Studies; Sirolimus; Sorafenib; Sunitinib; Thrombocytopenia	2011
Isomalyngamide A, A-1 and their analogs suppress cancer cell migration in vitro. European journal of medicinal chemistry, 2011, Volume: 46, Issue:9 Topics: Amides; Blotting, Western; Cell Line, Tumor; Cell Movement; Focal Adhesion Protein-Tyrosine Kinases; Humans; Integrin beta1; Magnetic Resonance Spectroscopy; Neoplasm Metastasis; Neoplasms; Proto-Oncogene Proteins c-akt; Pyrroles; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Infrared	2011
Metastatic renal mucinous tubular and spindle cell carcinoma. Atypical behavior of a rare, morphologically bland tumor. Annals of diagnostic pathology, 2012, Volume: 16, Issue:5 Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney Neoplasms; Middle Aged; Neoplasm Metastasis; Nephrectomy; Pyrroles; Rare Diseases; Sunitinib	2012
Sequential therapy with sunitinib and sorafenib in metastatic hepatocellular carcinoma. Investigational new drugs, 2012, Volume: 30, Issue:4 Topics: Adult; Aged; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Hepatocellular; Disease Progression; Female; Humans; Indoles; Liver Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrroles; Sorafenib; Sunitinib; Time Factors; Treatment Outcome	2012
Efficacy of re-challenging metastatic renal cell carcinoma with mTOR inhibitors. Acta oncologica (Stockholm, Sweden), 2011, Volume: 50, Issue:7 Topics: Antineoplastic Agents; Benzimidazoles; Carcinoma, Renal Cell; Everolimus; Humans; Indoles; Kidney Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Quinolones; Sirolimus; Sunitinib; TOR Serine-Threonine Kinases	2011
Intrinsic resistance to tyrosine kinase inhibitors is associated with poor clinical outcome in metastatic renal cell carcinoma. BMC cancer, 2011, Jul-14, Volume: 11 Topics: Adult; Aged; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Drug Resistance, Neoplasm; Female; Humans; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Prognosis; Protein Kinase Inhibitors; Pyridines; Pyrroles; Retrospective Studies; Sorafenib; Sunitinib; Time Factors; Treatment Outcome	2011
Prognostic model for survival in patients with metastatic renal cell carcinoma: results from the international kidney cancer working group. Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Aug-15, Volume: 17, Issue:16 Topics: Antibodies, Monoclonal, Humanized; Benzenesulfonates; Bevacizumab; Carcinoma, Renal Cell; Databases, Factual; Female; Humans; Indoles; International Cooperation; Kidney Neoplasms; Logistic Models; Male; Models, Biological; Multivariate Analysis; Neoplasm Metastasis; Niacinamide; Outcome Assessment, Health Care; Phenylurea Compounds; Prognosis; Protein Kinase Inhibitors; Pyridines; Pyrroles; Reproducibility of Results; Sorafenib; Sunitinib; Survival Analysis; Time Factors	2011
Flare up of symptoms after discontinuation of sunitinib in patient with lung cancer. Acta oncologica (Stockholm, Sweden), 2011, Volume: 50, Issue:7 Topics: Adenocarcinoma; Adenocarcinoma of Lung; Administration, Oral; Antineoplastic Agents; Combined Modality Therapy; Disease Progression; Female; Humans; Indoles; Lung Neoplasms; Middle Aged; Neoplasm Metastasis; Pyrroles; Sunitinib; Treatment Outcome; Withholding Treatment	2011
Sunitinib-induced changes in circulating endothelial cell-related proteins in patients with metastatic renal cell cancer. International journal of cancer, 2012, Aug-15, Volume: 131, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Sunitinib	2012
Utilizing pre-therapy clinical schema and initial CT changes to predict progression-free survival in patients with metastatic renal cell carcinoma on VEGF-targeted therapy: a preliminary analysis. Urologic oncology, 2013, Volume: 31, Issue:7 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Male; Middle Aged; Molecular Targeted Therapy; Neoplasm Metastasis; Niacinamide; Outcome Assessment, Health Care; Phenylurea Compounds; Prognosis; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Retrospective Studies; Risk Assessment; Risk Factors; Sorafenib; Sunitinib; Tomography, X-Ray Computed; Vascular Endothelial Growth Factor A	2013
Sunitinib re-challenge in metastatic renal cell carcinoma treated sequentially with tyrosine kinase inhibitors and everolimus. Anticancer research, 2011, Volume: 31, Issue:10 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Everolimus; Female; Humans; Indoles; Kidney Neoplasms; Middle Aged; Neoplasm Metastasis; Protein Kinase Inhibitors; Pyrroles; Radiography; Sirolimus; Sunitinib	2011
Third-line sunitinib following sequential use of cytokine therapy and sorafenib in Japanese patients with metastatic renal cell carcinoma. International journal of clinical oncology, 2013, Volume: 18, Issue:1 Topics: Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Indoles; Interferon-alpha; Interleukin-2; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Niacinamide; Phenylurea Compounds; Prognosis; Pyrroles; Retrospective Studies; Sorafenib; Sunitinib; Treatment Outcome	2013
[Twenty-one-year survival case of rectal GIST treated with combined therapies]. Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:12 Topics: Antineoplastic Agents; Benzamides; Combined Modality Therapy; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Neoplasm Metastasis; Piperazines; Pyrimidines; Pyrroles; Rectal Neoplasms; Recurrence; Sunitinib; Time Factors	2011
Efficacy and safety of vascular endothelial growth factor receptor tyrosine kinase inhibitors in patients with metastatic renal cell carcinoma and poor risk features. Journal of cancer research and clinical oncology, 2012, Volume: 138, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Carcinoma, Renal Cell; Drug Administration Schedule; Fatigue; Female; Humans; Indazoles; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Prognosis; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Retrospective Studies; Sorafenib; Sulfonamides; Sunitinib; Survival Analysis; Thrombocytopenia; Treatment Outcome; Young Adult	2012
Baseline quality of life as a prognostic survival tool in patients receiving sunitinib for metastatic renal cell carcinoma. British journal of cancer, 2012, Feb-14, Volume: 106, Issue:4 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Clinical Trials, Phase III as Topic; Disease-Free Survival; Female; Humans; Indoles; Interferon-alpha; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Prognosis; Pyrroles; Quality of Life; Randomized Controlled Trials as Topic; Sunitinib	2012
Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway. Cancer cell, 2012, Jan-17, Volume: 21, Issue:1 Topics: Animals; Antineoplastic Agents; Benzamides; Benzenesulfonates; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Crizotinib; Epithelial-Mesenchymal Transition; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Imatinib Mesylate; Indoles; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Metastasis; Niacinamide; Pericytes; Phenylurea Compounds; Piperazines; Piperidines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Signal Transduction; Sorafenib; Sunitinib; Tumor Cells, Cultured	2012
HGF/c-Met pathway is one of the mediators of sunitinib-induced tumor cell type-dependent metastasis. Cancer letters, 2012, Jul-01, Volume: 320, Issue:1 Topics: Angiogenesis Inhibitors; Animals; Breast Neoplasms; Cell Line, Tumor; Colorectal Neoplasms; Enzyme-Linked Immunosorbent Assay; Hepatocyte Growth Factor; Humans; Indoles; Lung Neoplasms; Lymphatic Metastasis; Mice; Mice, Nude; Neoplasm Metastasis; Neovascularization, Pathologic; Proto-Oncogene Proteins c-met; Pyrroles; Signal Transduction; Sunitinib	2012
Serum 20S proteasome is elevated in patients with renal cell carcinoma and associated with poor prognosis. British journal of cancer, 2012, Feb-28, Volume: 106, Issue:5 Topics: Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney Neoplasms; Male; Neoplasm Metastasis; Prognosis; Proteasome Endopeptidase Complex; Pyrroles; Sunitinib; Survival Analysis	2012
Second-line treatment for renal cell cancer. British journal of cancer, 2012, Feb-14, Volume: 106, Issue:4 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Drug Administration Schedule; Humans; Indazoles; Indoles; Kidney Neoplasms; Molecular Targeted Therapy; Neoplasm Metastasis; Prognosis; Pyrimidines; Pyrroles; Retreatment; Sulfonamides; Sunitinib	2012
Use of tyrosine kinase inhibitors in patients with metastatic kidney cancer receiving haemodialysis: a retrospective Italian survey. BJU international, 2012, Volume: 110, Issue:5 Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Benzenesulfonates; Contraindications; Female; Humans; Indoles; Kidney Failure, Chronic; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrroles; Renal Dialysis; Retrospective Studies; Sorafenib; Sunitinib	2012
Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model. The Journal of pathology, 2012, Volume: 227, Issue:4 Topics: Animals; Beclomethasone; Breast Neoplasms; Cell Movement; Cell Transformation, Neoplastic; Disease Models, Animal; Endothelial Cells; Humans; Indoles; Mice; Myeloid Cells; Neoplasm Metastasis; Neutrophils; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Signal Transduction; Sunitinib; Xenograft Model Antitumor Assays; Zebrafish	2012
Tyrosine kinase receptor inhibitor-targeted combined chemotherapy for metastatic bladder cancer. The Kaohsiung journal of medical sciences, 2012, Volume: 28, Issue:4 Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Epirubicin; Female; Humans; Indoles; Mice; Neoplasm Metastasis; Pyrroles; Receptor Protein-Tyrosine Kinases; Sunitinib; Urinary Bladder Neoplasms; Vascular Endothelial Growth Factor A	2012
Off-label use of sunitinib in patients with advanced, epithelial thyroid cancer: a retrospective analysis. Recent patents on endocrine, metabolic & immune drug discovery, 2012, Volume: 6, Issue:2 Topics: Adenocarcinoma, Follicular; Adenocarcinoma, Papillary; Aged; Antineoplastic Agents; Carcinoma; Carcinoma, Papillary; Disease-Free Survival; Female; Humans; Indoles; Male; Middle Aged; Neoplasm Metastasis; Off-Label Use; Protein-Tyrosine Kinases; Pyrroles; Retrospective Studies; Sunitinib; Thyroid Cancer, Papillary; Thyroid Neoplasms; Treatment Outcome	2012
HIF1A induces expression of the WASF3 metastasis-associated gene under hypoxic conditions. International journal of cancer, 2012, Sep-15, Volume: 131, Issue:6 Topics: Breast Neoplasms; Cell Hypoxia; Female; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indoles; Neoplasm Metastasis; Pyrroles; Transcription, Genetic; Tumor Microenvironment; Vascular Endothelial Growth Factor A; Wiskott-Aldrich Syndrome Protein Family	2012
Differential drug class-specific metastatic effects following treatment with a panel of angiogenesis inhibitors. The Journal of pathology, 2012, Volume: 227, Issue:4 Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Benzamides; Benzenesulfonates; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Imatinib Mesylate; In Vitro Techniques; Indoles; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Neoplasm Metastasis; Neovascularization, Pathologic; Niacinamide; Phenylurea Compounds; Piperazines; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Sorafenib; Sunitinib; Vascular Endothelial Growth Factor A	2012
Anti-VEGF antibody therapy does not promote metastasis in genetically engineered mouse tumour models. The Journal of pathology, 2012, Volume: 227, Issue:4 Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Antibodies, Anti-Idiotypic; Disease Models, Animal; Drug Therapy, Combination; Genetic Engineering; Indoles; Kaplan-Meier Estimate; Lung Neoplasms; Mice; Neoplasm Metastasis; Neuroendocrine Tumors; Pancreatic Neoplasms; Proto-Oncogene Proteins p21(ras); Pyrroles; Small Cell Lung Carcinoma; Sunitinib; Vascular Endothelial Growth Factor A	2012
Thyroid dysfunction in patients treated with tyrosine kinase inhibitors, sunitinib, sorafenib and axitinib, for metastatic renal cell carcinoma. Japanese journal of clinical oncology, 2012, Volume: 42, Issue:8 Topics: Adult; Aged; Antineoplastic Agents; Axitinib; Benzenesulfonates; Carcinoma, Renal Cell; Female; Humans; Imidazoles; Indazoles; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyridines; Pyrroles; Sorafenib; Sunitinib; Thyroid Diseases; Thyroid Gland; Thyrotoxicosis	2012
Gingival bleeding and jaw bone necrosis in patients with metastatic renal cell carcinoma receiving sunitinib: report of 2 cases with clinical implications. Oral surgery, oral medicine, oral pathology and oral radiology, 2012, Volume: 113, Issue:2 Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Carcinoma, Renal Cell; Female; Gingival Hemorrhage; Humans; Indoles; Kidney Neoplasms; Mandibular Diseases; Middle Aged; Neoplasm Metastasis; Osteonecrosis; Pyrroles; Sunitinib; Treatment Outcome; Young Adult	2012
Skin toxicity and efficacy of sunitinib and sorafenib in metastatic renal cell carcinoma: a national registry-based study. Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:12 Topics: Aged; Angiogenesis Inhibitors; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Exanthema; Female; Hand-Foot Syndrome; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyrroles; Registries; Retrospective Studies; Skin; Sorafenib; Sunitinib; Treatment Outcome	2012
Immunotherapy and targeted therapies in metastatic renal cell carcinoma: is there a preferred sequence? Cancer biotherapy & radiopharmaceuticals, 2012, Volume: 27, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Combined Modality Therapy; Cytokines; Female; Humans; Immunotherapy; Indoles; Interferon-alpha; Kidney Neoplasms; Male; Middle Aged; Molecular Targeted Therapy; Neoplasm Metastasis; Pyrroles; Retrospective Studies; Sunitinib	2012
Does sunitinib-induced hypothyroidism play a role in the activity of sunitinib in metastatic renal cell carcinoma? Chemotherapy, 2012, Volume: 58, Issue:3 Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Humans; Hypothyroidism; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Middle Aged; Neoplasm Metastasis; Nephrectomy; Prognosis; Pyrroles; Retrospective Studies; Sunitinib; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine	2012
Apricoxib, a novel inhibitor of COX-2, markedly improves standard therapy response in molecularly defined models of pancreatic cancer. Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Sep-15, Volume: 18, Issue:18 Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Synergism; Epithelial-Mesenchymal Transition; ErbB Receptors; Erlotinib Hydrochloride; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Metastasis; Neovascularization, Pathologic; Pancreatic Neoplasms; Pyrroles; Quinazolines; Sulfonamides	2012
Role of operative therapy in treatment of metastatic gastrointestinal stromal tumors. The Journal of surgical research, 2012, Volume: 177, Issue:2 Topics: Aged; Antineoplastic Agents; Benzamides; Disease-Free Survival; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Minnesota; Neoplasm Metastasis; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Retrospective Studies; Sunitinib	2012
Contrasting effects of sunitinib within in vivo models of metastasis. Angiogenesis, 2012, Volume: 15, Issue:4 Topics: Animals; Antineoplastic Agents; Indoles; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Positron-Emission Tomography; Pyrroles; Sunitinib; Tomography, X-Ray Computed	2012
Targeting angiogenesis in metastatic breast cancer. The oncologist, 2012, Volume: 17, Issue:8 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Breast Neoplasms; Capecitabine; Clinical Trials, Phase III as Topic; Deoxycytidine; Disease-Free Survival; Everolimus; Female; Fluorouracil; Humans; Indoles; Neoplasm Metastasis; Neovascularization, Pathologic; Niacinamide; Paclitaxel; Phenylurea Compounds; Pyrroles; Sirolimus; Sorafenib; Sunitinib; TOR Serine-Threonine Kinases; Vascular Endothelial Growth Factor A	2012
Decrease in blood miR-296 predicts chemotherapy resistance and poor clinical outcome in patients receiving systemic chemotherapy for metastatic colon cancer. International journal of colorectal disease, 2013, Volume: 28, Issue:6 Topics: Capecitabine; Colonic Neoplasms; Deoxycytidine; Disease Progression; Drug Resistance, Neoplasm; Fluorouracil; Humans; Indoles; MicroRNAs; Neoplasm Metastasis; Pyrroles; Sunitinib; Treatment Outcome	2013
Targeting neuroendocrine tumor: mixing standard options with novel therapies. Targeted oncology, 2012, Volume: 7, Issue:3 Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Combined Modality Therapy; Dacarbazine; Disease Progression; Drug Resistance, Neoplasm; Humans; Indoles; Medical Oncology; Neoplasm Metastasis; Neuroendocrine Tumors; Pancreatic Neoplasms; Pyrroles; Sunitinib; Temozolomide; Treatment Outcome	2012
Severe neurological symptoms in a patient with advanced renal cell carcinoma treated with sunitinib. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2013, Volume: 19, Issue:2 Topics: Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Neurotoxicity Syndromes; Posterior Leukoencephalopathy Syndrome; Pyrroles; Severity of Illness Index; Sunitinib	2013
Conditional survival of patients with metastatic renal-cell carcinoma. The Lancet. Oncology, 2012, Volume: 13, Issue:11 Topics: Carcinoma, Renal Cell; Humans; Indoles; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Prognosis; Pyrroles; Sirolimus; Sorafenib; Sunitinib; Survival Analysis	2012
Concomitant oral tyrosine kinase inhibitors and bisphosphonates in advanced renal cell carcinoma with bone metastases. British journal of cancer, 2012, Nov-06, Volume: 107, Issue:10 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Density Conservation Agents; Bone Neoplasms; Carcinoma, Renal Cell; Diphosphonates; Disease-Free Survival; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Osteonecrosis; Phenylurea Compounds; Prognosis; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrroles; Retrospective Studies; Sorafenib; Sunitinib; Treatment Outcome	2012
Treatment patterns: targeted therapies indicated for first-line management of metastatic renal cell carcinoma in a real-world setting. Clinical genitourinary cancer, 2013, Volume: 11, Issue:2 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Carcinoma, Renal Cell; Cohort Studies; Female; Humans; Indazoles; Indoles; Kidney Neoplasms; Male; Middle Aged; Molecular Targeted Therapy; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Retrospective Studies; Sirolimus; Sorafenib; Sulfonamides; Sunitinib; United States	2013
Beyond the maths of biology: long-term spontaneous tumoral regression after sunitinib withdrawal. Clinical genitourinary cancer, 2013, Volume: 11, Issue:2 Topics: Aged; Angiogenesis Inhibitors; Antineoplastic Agents; Carcinoma, Renal Cell; Humans; Indoles; Kidney Neoplasms; Male; Neoplasm Metastasis; Pyrroles; Remission, Spontaneous; Sunitinib	2013
Response evaluation criteria in solid tumors response of the primary lesion in metastatic renal cell carcinomas treated with sunitinib: does the primary lesion have to be regarded as a target lesion? Clinical genitourinary cancer, 2013, Volume: 11, Issue:3 Topics: Adult; Aged; Angiogenesis Inhibitors; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Nephrectomy; Pyrroles; Retrospective Studies; Sunitinib; Survival; Treatment Outcome	2013
Antiangiogenic agents, chemotherapy, and the treatment of metastatic transitional cell carcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Feb-20, Volume: 31, Issue:6 Topics: Acute Disease; Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Deoxycytidine; Gemcitabine; Humans; Indoles; Male; Neoplasm Metastasis; Neutropenia; Pancreatitis; Pyrroles; Sunitinib; Treatment Outcome; Ureteral Neoplasms; Urinary Bladder Neoplasms	2013
Combined therapy of local and metastatic 4T1 breast tumor in mice using SU6668, an inhibitor of angiogenic receptor tyrosine kinases, and the immunostimulator B7.2-IgG fusion protein. Cancer research, 2002, Oct-15, Volume: 62, Issue:20 Topics: Angiogenesis Inhibitors; Animals; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; B7-2 Antigen; Cancer Vaccines; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Combined Modality Therapy; Female; Immunoglobulin G; Indoles; Interferon-gamma; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Mammary Neoplasms, Experimental; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Oxindoles; Propionates; Protein-Tyrosine Kinases; Pyrroles; Recombinant Fusion Proteins; Spleen	2002
Blockade of the epidermal growth factor receptor signaling inhibits angiogenesis leading to regression of human renal cell carcinoma growing orthotopically in nude mice. Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Renal Cell; Deoxycytidine; DNA-Binding Proteins; Down-Regulation; Endothelial Growth Factors; Enzyme Inhibitors; ErbB Receptors; Gemcitabine; Immunohistochemistry; In Situ Nick-End Labeling; Intercellular Signaling Peptides and Proteins; Kidney; Lung; Lymphokines; Mice; Mice, Nude; Neoplasm Metastasis; Neovascularization, Pathologic; Phosphorylation; Proliferating Cell Nuclear Antigen; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Signal Transduction; STAT3 Transcription Factor; Time Factors; Trans-Activators; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	2002
Isoprenylation is necessary for the full invasive potential of RhoA overexpression in human melanoma cells. The Journal of investigative dermatology, 2002, Volume: 119, Issue:5 Topics: Animals; Anticholesteremic Agents; Atorvastatin; Biocompatible Materials; Cell Movement; Collagen; Drug Combinations; Gene Expression Regulation, Neoplastic; Heptanoic Acids; Humans; Laminin; Melanoma; Neoplasm Invasiveness; Neoplasm Metastasis; Protein Prenylation; Protein Processing, Post-Translational; Proteoglycans; Pyrroles; rhoA GTP-Binding Protein; Signal Transduction; Skin Neoplasms; Transcription, Genetic; Tumor Cells, Cultured	2002
Colorectal cancer: targeting metastasis and angiogenesis. Clinical colorectal cancer, 2002, Volume: 1, Issue:4 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Colorectal Neoplasms; Disease Progression; Extracellular Matrix; Humans; Indoles; Matrix Metalloproteinases; Neoplasm Metastasis; Neovascularization, Pathologic; Pyrroles	2002
Interleukin-2 and cancer: critical analysis of results, problems and expectations. Medical hypotheses, 2003, Volume: 60, Issue:2 Topics: Cytokines; Humans; Immunotherapy; Indoles; Interleukin-2; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Oxindoles; Propionates; Protein-Tyrosine Kinases; Pyrroles; Receptors, Interleukin-2	2003
Blockade of epidermal growth factor receptor signaling in tumor cells and tumor-associated endothelial cells for therapy of androgen-independent human prostate cancer growing in the bone of nude mice. Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Volume: 9, Issue:3 Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Blotting, Western; Bone and Bones; Bone Neoplasms; Dose-Response Relationship, Drug; Endothelial Growth Factors; Endothelium, Vascular; ErbB Receptors; Fibroblast Growth Factor 2; Immunohistochemistry; In Situ Nick-End Labeling; Intercellular Signaling Peptides and Proteins; Interleukin-8; Lymphokines; Male; Mice; Mice, Nude; Microscopy, Fluorescence; Neoplasm Metastasis; Neoplasm Transplantation; Paclitaxel; Phosphorylation; Platelet Endothelial Cell Adhesion Molecule-1; Proliferating Cell Nuclear Antigen; Prostatic Neoplasms; Pyrimidines; Pyrroles; Signal Transduction; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	2003
Expression profiling of blood samples from an SU5416 Phase III metastatic colorectal cancer clinical trial: a novel strategy for biomarker identification. BMC cancer, 2003, Feb-07, Volume: 3 Topics: Aged; Angiogenesis Inhibitors; Antigens, CD; Biomarkers, Tumor; CD24 Antigen; Clinical Trials, Phase III as Topic; Colorectal Neoplasms; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Indoles; Lactoferrin; Leukocytes, Mononuclear; Male; Matrix Metalloproteinase 9; Membrane Glycoproteins; Middle Aged; Neoplasm Metastasis; Oligonucleotide Array Sequence Analysis; Predictive Value of Tests; Protein-Tyrosine Kinases; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction	2003
Atorvastatin prevents RhoC isoprenylation, invasion, and metastasis in human melanoma cells. Molecular cancer therapeutics, 2003, Volume: 2, Issue:10 Topics: Animals; Atorvastatin; Cell Movement; Green Fluorescent Proteins; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Immunoblotting; Immunohistochemistry; Luciferases; Luminescent Proteins; Melanoma; Mice; Mice, SCID; Microscopy, Fluorescence; Neoplasm Invasiveness; Neoplasm Metastasis; Plasmids; Protein Processing, Post-Translational; Pyrroles; ras Proteins; rho GTP-Binding Proteins; rhoC GTP-Binding Protein; Serum Response Factor; Subcellular Fractions; Time Factors; Tumor Cells, Cultured	2003
Proof of target for SU11654: inhibition of KIT phosphorylation in canine mast cell tumors. Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Nov-15, Volume: 9, Issue:15 Topics: Animals; Dog Diseases; Dogs; Enzyme Inhibitors; Indoles; Mast Cells; Mast-Cell Sarcoma; Mitogen-Activated Protein Kinases; Neoplasm Metastasis; Phosphorylation; Proto-Oncogene Proteins c-kit; Pyrroles; Recurrence	2003
Relationship between antiapoptotic molecules and metastatic potency and the involvement of DNA-dependent protein kinase in the chemosensitization of metastatic human cancer cells by epidermal growth factor receptor blockade. The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:3 Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Line, Tumor; DNA-Activated Protein Kinase; DNA-Binding Proteins; Drug Synergism; Electrophoretic Mobility Shift Assay; ErbB Receptors; Etoposide; Genes, MDR; Humans; Indicators and Reagents; Melanoma; Neoplasm Metastasis; Nuclear Proteins; Protein Serine-Threonine Kinases; Pyrimidines; Pyrroles; Radiation-Sensitizing Agents; Rats	2004
Inhibition of peritoneal dissemination of ovarian cancer by tyrosine kinase receptor inhibitor SU6668 (TSU-68). International journal of cancer, 2005, Mar-20, Volume: 114, Issue:2 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line, Tumor; Enzyme Inhibitors; Female; Humans; Indoles; Mice; Mice, Nude; Neoplasm Metastasis; Ovarian Neoplasms; Oxindoles; Platelet-Derived Growth Factor; Propionates; Protein-Tyrosine Kinases; Pyrroles; Survival Analysis; Transplantation, Heterologous; Vascular Endothelial Growth Factor A	2005
The receptor tyrosine kinase inhibitor SU11248 impedes endothelial cell migration, tubule formation, and blood vessel formation in vivo, but has little effect on existing tumor vessels. Angiogenesis, 2004, Volume: 7, Issue:3 Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Blood Vessels; Carcinoma, Lewis Lung; Cell Movement; Cells, Cultured; Endothelium, Vascular; Humans; Indoles; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neovascularization, Pathologic; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Secondary Prevention; Sunitinib; Umbilical Cord	2004
Treatment options in metastatic renal carcinoma: an embarrassment of riches. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Jan-01, Volume: 24, Issue:1 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Humans; Indoles; Kidney Neoplasms; Neoplasm Metastasis; Pyrroles; Receptors, Platelet-Derived Growth Factor; Receptors, Vascular Endothelial Growth Factor; Sunitinib	2006
Antiangiogenic combination tumor therapy blocking alpha(v)-integrins and VEGF-receptor-2 increases therapeutic effects in vivo. International journal of cancer, 2006, Jul-15, Volume: 119, Issue:2 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Cricetinae; Disease Progression; Indoles; Integrin alphaV; Male; Mesocricetus; Microcirculation; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neovascularization, Pathologic; Pyrroles; Vascular Endothelial Growth Factor Receptor-2	2006
Patients with metastatic renal cell carcinoma with long-term disease-free survival after treatment with sunitinib and resection of residual metastases. Clinical genitourinary cancer, 2006, Volume: 5, Issue:3 Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Combined Modality Therapy; Disease-Free Survival; Humans; Indoles; Interferon-alpha; Interleukin-2; Kidney Neoplasms; Male; Neoplasm Metastasis; Nephrectomy; Pyrroles; Sunitinib	2006
Effects of vascular endothelial growth factor receptor inhibitor SU5416 and prostacyclin on murine lung metastasis. Anti-cancer drugs, 2007, Volume: 18, Issue:3 Topics: Animals; Carcinoma, Lewis Lung; Cell Adhesion; Cells, Cultured; Disease Progression; Epoprostenol; Indoles; Liver Neoplasms; Lung Neoplasms; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasm Transplantation; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Splenic Neoplasms	2007
Preclinical in vivo study of new insulin-like growth factor-I receptor--specific inhibitor in Ewing's sarcoma. Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Feb-15, Volume: 13, Issue:4 Topics: Animals; Female; Humans; Mice; Mice, Nude; Neoplasm Metastasis; Pyrimidines; Pyrroles; Receptor, IGF Type 1; Sarcoma, Ewing; Xenograft Model Antitumor Assays	2007
Newly approved therapies for RCC and their effect on the standard of care. Clinical advances in hematology & oncology : H&O, 2007, Volume: 5, Issue:1 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Benzenesulfonates; Bevacizumab; Carcinoma, Renal Cell; Clinical Trials as Topic; Humans; Indoles; Interferons; Kidney Neoplasms; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Protein-Tyrosine Kinases; Pyridines; Pyrroles; Sirolimus; Sorafenib; Sunitinib; Von Hippel-Lindau Tumor Suppressor Protein	2007
Emphysematous cholecystitis in a patient with gastrointestinal stromal tumor treated with sunitinib. Pharmacotherapy, 2007, Volume: 27, Issue:5 Topics: Acute Disease; Angiogenesis Inhibitors; Anti-Bacterial Agents; Antineoplastic Agents; Cholecystostomy; Emphysematous Cholecystitis; Gastrointestinal Stromal Tumors; Humans; Hyperbilirubinemia; Indoles; Leukocytosis; Male; Middle Aged; Neoplasm Metastasis; Probability; Pyrroles; Sunitinib; Tomography, X-Ray Computed	2007
[Adverse effects of the tyrosine-kinase inhibitor sunitinib, a new drug for the treatment of advanced renal-cell cancer]. Nederlands tijdschrift voor geneeskunde, 2007, May-19, Volume: 151, Issue:20 Topics: Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Fatal Outcome; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Protein-Tyrosine Kinases; Pyrroles; Safety; Sunitinib; Treatment Outcome	2007
Hypertension as a predictive factor of Sunitinib activity. Annals of oncology : official journal of the European Society for Medical Oncology, 2007, Volume: 18, Issue:6 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Hypertension; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Sunitinib; Treatment Outcome	2007
[Interdisciplinary recommendations on targeted therapy in the treatment of renal cell carcinoma]. Aktuelle Urologie, 2007, Volume: 38, Issue:4 Topics: Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Controlled Clinical Trials as Topic; Humans; Immunologic Factors; Immunotherapy; Indoles; Interferon-alpha; Kidney; Kidney Neoplasms; Meta-Analysis as Topic; Neoplasm Metastasis; Nephrectomy; Niacinamide; Phenylurea Compounds; Prognosis; Protein Kinase Inhibitors; Pyridines; Pyrroles; Sorafenib; Sunitinib; Time Factors	2007
Reversible posterior leukoencephalopathy syndrome induced by sunitinib. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Aug-10, Volume: 25, Issue:23 Topics: Aged; Antineoplastic Agents; Bone Neoplasms; Brain; Brain Diseases; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney Neoplasms; Magnetic Resonance Imaging; Neoplasm Metastasis; Pyrroles; Seizures; Sunitinib; Syndrome; Treatment Outcome	2007
Potential biomarkers in metastatic gastrointestinal stromal tumors. Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Oct-15, Volume: 13, Issue:20 Topics: Antineoplastic Agents; Biomarkers, Tumor; Blood Platelets; Bone Marrow; Flow Cytometry; Gastrointestinal Stromal Tumors; Humans; Indoles; Interleukin-6; Neoplasm Metastasis; Phenotype; Pyrroles; Sunitinib; Thrombopoietin	2007
Prolonged complete responses and near-complete responses to sunitinib in metastatic renal cell carcinoma. Clinical genitourinary cancer, 2007, Volume: 5, Issue:7 Topics: Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Humans; Indoles; Kidney Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Sunitinib; Time Factors	2007
Molecule of the month. Elesclomol and obatoclax mesylate. Drug news & perspectives, 2008, Volume: 21, Issue:2 Topics: Antineoplastic Agents; Controlled Clinical Trials as Topic; Humans; Hydrazines; Indoles; Melanoma; Neoplasm Metastasis; Neoplasms; Pyrroles	2008
Rapid adhesion and spread of non-adherent colon cancer Colo201 cells induced by the protein kinase inhibitors, K252a and KT5720 and suppression of the adhesion by the immunosuppressants FK506 and cyclosporin A. Cell structure and function, 1998, Volume: 23, Issue:5 Topics: Adenocarcinoma; Carbazoles; Cell Adhesion; Cell Adhesion Molecules; Colonic Neoplasms; Cyclosporine; Cytoskeletal Proteins; Enzyme Inhibitors; Extracellular Matrix; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunosuppressive Agents; Indole Alkaloids; Indoles; Integrins; Neoplasm Metastasis; Paxillin; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Pyrroles; Sulfonamides; Tacrolimus; Tumor Cells, Cultured; Tyrosine	1998
Inhibition of PC-3 human androgen-independent prostate cancer and its metastases by cytotoxic somatostatin analogue AN-238. Cancer research, 1999, Apr-15, Volume: 59, Issue:8 Topics: Androgens; Animals; Antibiotics, Antineoplastic; Doxorubicin; Gene Expression; Humans; Lymphatic Metastasis; Male; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Prostatic Neoplasms; Pyrroles; Receptors, Somatostatin; Somatostatin; Transplantation, Heterologous; Tumor Cells, Cultured	1999
Inhibition of angiogenesis by blocking activation of the vascular endothelial growth factor receptor 2 leads to decreased growth of neurogenic sarcomas. Cancer research, 1999, Nov-01, Volume: 59, Issue:21 Topics: Angiogenesis Inhibitors; Animals; Chemotherapy, Adjuvant; Dose-Response Relationship, Drug; Endothelial Growth Factors; Enzyme Inhibitors; Indoles; Lymphokines; Male; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Transplantation; Neovascularization, Pathologic; Neurofibromatosis 1; Neurons; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Sarcoma; Time Factors; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	1999
Vascular endothelial growth factor in human colon cancer: biology and therapeutic implications. The oncologist, 2000, Volume: 5 Suppl 1 Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Cell Division; Colonic Neoplasms; Disease Models, Animal; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Inhibitors; Humans; Indoles; Liver Neoplasms; Lymphokines; Mice; Neoplasm Metastasis; Neovascularization, Pathologic; Prognosis; Protein Isoforms; Protein-Tyrosine Kinases; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Mitogen; Receptors, Vascular Endothelial Growth Factor; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	2000
Inhibition of growth and metastatic progression of pancreatic carcinoma in hamster after somatostatin receptor subtype 2 (sst2) gene expression and administration of cytotoxic somatostatin analog AN-238. Proceedings of the National Academy of Sciences of the United States of America, 2000, Aug-01, Volume: 97, Issue:16 Topics: Animals; Antibiotics, Antineoplastic; Cadherins; Cell Division; Cricetinae; Cytotoxins; Doxorubicin; Fungal Proteins; GTPase-Activating Proteins; Intracellular Signaling Peptides and Proteins; Male; Mesocricetus; Neoplasm Metastasis; Pancreatic Neoplasms; Phosphorylation; Protein Phosphatase 1; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Pyrroles; Saccharomyces cerevisiae Proteins; Tumor Cells, Cultured; Tyrosine	2000
Optimization for the blockade of epidermal growth factor receptor signaling for therapy of human pancreatic carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:8 Topics: Administration, Oral; Animals; Antineoplastic Agents; Cell Division; Deoxycytidine; Drug Administration Schedule; Drug Therapy, Combination; Endothelial Growth Factors; Enzyme Inhibitors; ErbB Receptors; Gemcitabine; Humans; Immunohistochemistry; Interleukin-8; Lymphokines; Male; Mice; Mice, Nude; Neoplasm Metastasis; Pancreatic Neoplasms; Phosphorylation; Platelet Endothelial Cell Adhesion Molecule-1; Proliferating Cell Nuclear Antigen; Pyrimidines; Pyrroles; Ribonucleotide Reductases; Signal Transduction; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Xenograft Model Antitumor Assays	2001
Blockade of vascular endothelial growth factor receptor and epidermal growth factor receptor signaling for therapy of metastatic human pancreatic cancer. Cancer research, 2002, Apr-01, Volume: 62, Issue:7 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Division; Deoxycytidine; Endothelium, Vascular; ErbB Receptors; Gemcitabine; Humans; Immunohistochemistry; Male; Mice; Mice, Nude; Neoplasm Metastasis; Neovascularization, Pathologic; Pancreatic Neoplasms; Phthalazines; Pyridines; Pyrimidines; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Signal Transduction; Xenograft Model Antitumor Assays	2002
Photophysical properties and photodynamic activity in vivo of some tetrapyrroles. Biophysical chemistry, 1990, Volume: 35, Issue:2-3 Topics: Animals; Chemical Phenomena; Chemistry, Physical; Female; Fluorescence; Luminescent Measurements; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Metastasis; Neoplasms, Experimental; Photochemistry; Photochemotherapy; Pyrroles; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet	1990