Page last updated: 2024-08-18

pyrroles and Medulloblastoma

pyrroles has been researched along with Medulloblastoma in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Badodi, S; Benjamin-Ombo, VA; Frisira, E; Michod, D; Niklison-Chirou, MV; Rashid, F; Varma, SN1
Finlay, JL; Li, C; Lin, J; Ma, L; Pierson, CR; Wei, J1
Bradshaw, TD; Coyle, B; Grundy, RG; Kerr, ID; Kimishi, I; Korshunov, A; Othman, RT; Pfister, SM; Storer, LC1
Bolin, S; Brunner, A; Čančer, M; Cho, YJ; Hutter, S; Jones, DT; Kawauchi, D; Kool, M; Korshunov, A; Malyukova, A; Pfister, SM; Rosén, G; Sangfelt, O; Savov, V; Spruck, C; Sundström, A; Suryo Rahmanto, A; Swartling, FJ; Taylor, MD; Weishaupt, H1
Hedvat, M; Jove, V; Van Meter, TE; Xin, H; Yang, F; Yu, H1
Abouantoun, TJ; Castellino, RC; MacDonald, TJ1
Lin, F; Lin, J; Rao, J; Sheng, H; Yang, L; Yin, B; Zhang, N; Zhou, H1
Baba, A; Hattori, H; Ishimura, Y; Kondo, S; Miyamoto, M; Nishihara, M; Oguro, Y; Ohashi, T; Sasaki, S; Sato, Y; Shibata, S; Shiokawa, Z; Tanaka, T; Tanaka, Y; Tojo, H; Yamakawa, H; Yamamoto, Y1

Other Studies

8 other study(ies) available for pyrroles and Medulloblastoma

ArticleYear
NPI-0052 and γ-radiation induce a synergistic apoptotic effect in medulloblastoma.
    Cell death & disease, 2019, 10-16, Volume: 10, Issue:11

    Topics: Apoptosis; Cell Line, Tumor; Cerebellar Neoplasms; Chemoradiotherapy; Gamma Rays; Humans; Lactones; Medulloblastoma; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrroles

2019
Targeting Upstream Kinases of STAT3 in Human Medulloblastoma Cells.
    Current cancer drug targets, 2019, Volume: 19, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Movement; Cell Proliferation; Cerebellar Neoplasms; Cisplatin; Dasatinib; Drug Synergism; Humans; Medulloblastoma; Nitriles; Piperidines; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Pyrroles; src-Family Kinases; STAT3 Transcription Factor; Tumor Cells, Cultured

2019
Overcoming multiple drug resistance mechanisms in medulloblastoma.
    Acta neuropathologica communications, 2014, May-30, Volume: 2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Cells, Cultured; Cerebellar Neoplasms; Child; Child, Preschool; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Indoles; Male; Medulloblastoma; Minor Histocompatibility Antigens; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Temozolomide; Tumor Cells, Cultured; Tumor Suppressor Proteins

2014
FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma.
    The EMBO journal, 2016, 10-17, Volume: 35, Issue:20

    Topics: Aniline Compounds; Animals; Benzamides; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Chromones; Cisplatin; F-Box Proteins; F-Box-WD Repeat-Containing Protein 7; Glycogen Synthase Kinase 3; HEK293 Cells; Humans; Medulloblastoma; Mice, Nude; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; SOX9 Transcription Factor; TOR Serine-Threonine Kinases; Ubiquitin-Protein Ligases; Ubiquitination

2016
Sunitinib induces apoptosis and growth arrest of medulloblastoma tumor cells by inhibiting STAT3 and AKT signaling pathways.
    Molecular cancer research : MCR, 2010, Volume: 8, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Fatty Acids, Monounsaturated; Gene Expression Regulation, Neoplastic; Humans; Indoles; Medulloblastoma; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrroles; Signal Transduction; STAT3 Transcription Factor; Sunitinib; Transfection

2010
Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells.
    Journal of neuro-oncology, 2011, Volume: 101, Issue:2

    Topics: Angiogenesis Inducing Agents; Animals; Antineoplastic Agents; Becaplermin; Cell Count; Cell Line, Tumor; Cell Movement; Cells, Cultured; Dose-Response Relationship, Drug; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Humans; Indoles; Medulloblastoma; Mice; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; PTEN Phosphohydrolase; Pyrroles; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Sunitinib; Time Factors

2011
The insulin-like growth factor-I receptor kinase inhibitor NVP-ADW742 sensitizes medulloblastoma to the effects of chemotherapy.
    Oncology reports, 2011, Volume: 25, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Separation; Dacarbazine; Flow Cytometry; Humans; Inhibitory Concentration 50; Medulloblastoma; Polymerase Chain Reaction; Pyrimidines; Pyrroles; Receptor, IGF Type 1; Temozolomide

2011
Discovery of the investigational drug TAK-441, a pyrrolo[3,2-c]pyridine derivative, as a highly potent and orally active hedgehog signaling inhibitor: modification of the core skeleton for improved solubility.
    Bioorganic & medicinal chemistry, 2012, Sep-15, Volume: 20, Issue:18

    Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discovery; Hedgehog Proteins; Humans; Kruppel-Like Transcription Factors; Medulloblastoma; Mice; Mice, Nude; Models, Molecular; Molecular Structure; NIH 3T3 Cells; Pyridines; Pyrroles; RNA, Messenger; Signal Transduction; Solubility; Structure-Activity Relationship; Transplantation, Homologous; Zinc Finger Protein GLI1

2012