Page last updated: 2024-08-18

pyrroles and Macular Degeneration

pyrroles has been researched along with Macular Degeneration in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (33.33)29.6817
2010's11 (61.11)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Amaral, J; Bharti, K; Bose, D; Campos, MM; Chang, J; Dejene, R; Ferrer, M; George, A; Hanson, E; Jha, BS; Karla, BS; King, R; Lal, M; Liang, G; McGaughey, D; Memon, O; Miyagishima, KJ; Nimmagadda, M; Ortolan, D; Qureshy, Z; Rising, A; Sharma, R; Wan, Q1
Collier, RJ; Crabb, JS; Crabb, JW; Gu, J; Hollyfield, JG; Kapin, MA; Rayborn, ME; Renganathan, K; Romano, C; Salomon, RG1
Ballmick, A; Cano, M; Cruz-Guilloty, F; Duffort, S; Ebrahimi, KB; Handa, JT; Laird, JM; Perez, VL; Saeed, AM; Salomon, RG; Tan, Y; Wang, H1
Cruz-Guilloty, F; Duffort, S; Ivanov, D; Laird, JM; Perez, VL; Saeed, AM; Salomon, RG; Wang, H1
Allimuthu, J; Chen, FK; Da Cruz, L; Esposti, SD; Keane, PA; Patel, PJ; Tah, V; Tufail, A1
Barnes, KD; Chen, P; Cioffi, CL; Conlon, MP; Cywin, CL; Dobri, N; Freeman, EE; Johnson, G; Kitchen, DB; Martin, WH; Michelotti, E; Pearson, PG; Petrukhin, K; Racz, B; Schwarz, DM; Stafford, DG; Zhu, L1
Coutinho, FP; Ramtin, A; Rupenthal, ID; Seyfoddin, A; Svirskis, D; Waterhouse, GI1
Crabb, JW; Gu, J; Gu, X; Nagaraj, RH; Ni, J; Yuan, X; Yue, X1
Choi, J; Crabb, J; Gu, X; Hong, L; Jaffe, K; Laird, J; Lu, L; Salomon, RG1
Hollyfield, JG1
Hollyfield, JG; Perez, VL; Salomon, RG1
Bena, J; Crabb, JW; Gu, J; Gu, X; Hagstrom, SA; Narendra, U; Pauer, GJ; Peachey, NS; Salomon, RG; Sturgill, GM; Yue, X1
Berna, MJ; Csaky, KG; Gordiyenko, N; Grierson, R; Kunst, F; Richard, G; Strunnikova, NV; Thill, M; Wege, H1
Hollyfield, JG; Hong, L; Salomon, RG1
Crabb, JW; Gu, X; Hollyfield, JG; Meer, SG; Miyagi, M; Rayborn, ME; Salomon, RG1
Anand-Apte, B; Crabb, JW; Ebrahem, Q; Gu, X; Lu, L; Renganathan, K; Salomon, RG; Sears, J; Vasanji, A2
Bonilha, VL; Hollyfield, JG; Lu, L; Perez, VL; Rayborn, ME; Salomon, RG; Shadrach, KG; Ufret, RL; Yang, X1

Reviews

2 review(s) available for pyrroles and Macular Degeneration

ArticleYear
Discovery of carboxyethylpyrroles (CEPs): critical insights into AMD, autism, cancer, and wound healing from basic research on the chemistry of oxidized phospholipids.
    Chemical research in toxicology, 2011, Nov-21, Volume: 24, Issue:11

    Topics: Animals; Antibodies; Autistic Disorder; CD36 Antigens; Cornea; Corneal Neovascularization; Endothelial Cells; Humans; Macular Degeneration; Mice; Mice, Knockout; Neoplasms; Oxidation-Reduction; Phospholipids; Protein Processing, Post-Translational; Pyrroles; Retinal Rod Photoreceptor Cells; Toll-Like Receptor 2; Wound Healing

2011
Carboxyethylpyrrole adducts, age-related macular degeneration and neovascularization.
    Advances in experimental medicine and biology, 2008, Volume: 613

    Topics: Aged, 80 and over; Aging; Allantois; Animals; Chick Embryo; Child; Humans; Macular Degeneration; Mice; Middle Aged; Models, Biological; Molecular Structure; Neovascularization, Pathologic; Pyrroles

2008

Other Studies

16 other study(ies) available for pyrroles and Macular Degeneration

ArticleYear
Epithelial phenotype restoring drugs suppress macular degeneration phenotypes in an iPSC model.
    Nature communications, 2021, 12-15, Volume: 12, Issue:1

    Topics: Alleles; Aminocaproic Acid; Complement Factor H; Drug Evaluation, Preclinical; Humans; Induced Pluripotent Stem Cells; Macular Degeneration; Models, Biological; Phenotype; Pyridines; Pyrroles; Retinal Pigment Epithelium

2021
CEP biomarkers as potential tools for monitoring therapeutics.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Animals; Autoantibodies; Biomarkers; Disease Models, Animal; Docosahexaenoic Acids; Light; Macular Degeneration; Male; Oxidation-Reduction; Pyrroles; Rats; Retina

2013
T cells and macrophages responding to oxidative damage cooperate in pathogenesis of a mouse model of age-related macular degeneration.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Animals; Biological Transport; Cyclosporine; Disease Models, Animal; Female; Humans; Immunization; Interferon-gamma; Interleukin-7; Macrophages; Macular Degeneration; Male; Mice; Oxidative Stress; Pyrroles; Retinal Pigment Epithelium; Sirolimus; T-Lymphocytes

2014
The oxidative stress product carboxyethylpyrrole potentiates TLR2/TLR1 inflammatory signaling in macrophages.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Animals; Gene Expression Regulation; Humans; Immunity, Innate; Inflammation; Lipid Peroxidation; Macrophages; Macular Degeneration; Mice; Oxidative Stress; Pyrroles; Signal Transduction; Toll-Like Receptor 1; Toll-Like Receptor 2; Toll-Like Receptor 6

2014
Repeatability of retinal thickness and volume metrics in neovascular age-related macular degeneration using the Topcon 3DOCT-1000.
    Indian journal of ophthalmology, 2014, Volume: 62, Issue:9

    Topics: Aged; Aged, 80 and over; Algorithms; Contrast Media; Cyclic N-Oxides; Female; Humans; Macular Degeneration; Male; Middle Aged; Pyrroles; Reproducibility of Results; Retina; Retinal Neovascularization; Retrospective Studies; Tomography, Optical Coherence

2014
Bicyclic [3.3.0]-Octahydrocyclopenta[c]pyrrolo Antagonists of Retinol Binding Protein 4: Potential Treatment of Atrophic Age-Related Macular Degeneration and Stargardt Disease.
    Journal of medicinal chemistry, 2015, Aug-13, Volume: 58, Issue:15

    Topics: Animals; Bridged Bicyclo Compounds; Dogs; Geographic Atrophy; Humans; Macular Degeneration; Madin Darby Canine Kidney Cells; Pyrroles; Rats; Rats, Sprague-Dawley; Retinol-Binding Proteins, Plasma; Stargardt Disease; Structure-Activity Relationship

2015
Cytotoxicity considerations and electrically tunable release of dexamethasone from polypyrrole for the treatment of back-of-the-eye conditions.
    Drug delivery and translational research, 2016, Volume: 6, Issue:6

    Topics: Cell Line; Cell Survival; Delayed-Action Preparations; Dexamethasone; Drug Delivery Systems; Drug Liberation; Electrochemistry; Humans; Macular Degeneration; Macular Edema; Polymerization; Polymers; Pyrroles

2016
Plasma protein pentosidine and carboxymethyllysine, biomarkers for age-related macular degeneration.
    Molecular & cellular proteomics : MCP, 2009, Volume: 8, Issue:8

    Topics: Aged; Aged, 80 and over; Arginine; Autoantibodies; Biomarkers; Blood Proteins; Case-Control Studies; Chromatography, Liquid; Female; Fluorometry; Humans; Logistic Models; Lysine; Macular Degeneration; Male; Mass Spectrometry; Middle Aged; Pyrroles

2009
Synthesis and structural characterization of carboxyethylpyrrole-modified proteins: mediators of age-related macular degeneration.
    Bioorganic & medicinal chemistry, 2009, Nov-01, Volume: 17, Issue:21

    Topics: Amino Acid Sequence; Animals; Antibodies; Biotinylation; Disease Models, Animal; Macular Degeneration; Mice; Peptides; Protein Denaturation; Pyrroles; Retina; Serum Albumin; Trypsin

2009
Age-related macular degeneration: the molecular link between oxidative damage, tissue-specific inflammation and outer retinal disease: the Proctor lecture.
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:3

    Topics: Animals; Autoantibodies; Awards and Prizes; Complement Activation; Disease Models, Animal; DNA Adducts; Florida; Humans; Macular Degeneration; Ophthalmology; Oxidative Stress; Propionates; Pyrroles; Retinal Drusen; Retinal Pigment Epithelium; Societies, Scientific

2010
A hapten generated from an oxidation fragment of docosahexaenoic acid is sufficient to initiate age-related macular degeneration.
    Molecular neurobiology, 2010, Volume: 41, Issue:2-3

    Topics: Animals; Complement Fixation Tests; Disease Models, Animal; Docosahexaenoic Acids; Haptens; Humans; Macular Degeneration; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Pyrroles; Retina; Serum Albumin

2010
Proteomic and genomic biomarkers for age-related macular degeneration.
    Advances in experimental medicine and biology, 2010, Volume: 664

    Topics: Autoantibodies; Biomarkers; Genotype; Humans; Macular Degeneration; Proteomics; Pyrroles; Risk Factors; Sensitivity and Specificity

2010
SU5416 induces premature senescence in endothelial progenitor cells from patients with age-related macular degeneration.
    Molecular vision, 2011, Jan-10, Volume: 17

    Topics: Apoptosis; Cellular Senescence; Endothelial Cells; Humans; Indoles; Macular Degeneration; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Receptors, CXCR4; Signal Transduction; Stem Cells; Treatment Outcome; Umbilical Veins; Vascular Endothelial Growth Factor Receptor-2

2011
Carboxyethylpyrrole protein adducts and autoantibodies, biomarkers for age-related macular degeneration.
    The Journal of biological chemistry, 2003, Oct-24, Volume: 278, Issue:43

    Topics: Albumins; Animals; Antibodies; Autoantibodies; Biomarkers; Case-Control Studies; Docosahexaenoic Acids; Fatty Acids, Unsaturated; Humans; Immunohistochemistry; Macular Degeneration; Mice; Oxidation-Reduction; Oxygen; Pyrroles; Retina; Rod Cell Outer Segment

2003
Carboxyethylpyrrole oxidative protein modifications stimulate neovascularization: Implications for age-related macular degeneration.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Sep-05, Volume: 103, Issue:36

    Topics: Aged, 80 and over; Allantois; Animals; Bruch Membrane; Cell Culture Techniques; Cell Line; Cells, Cultured; Chick Embryo; Child; Chorion; Choroidal Neovascularization; Dose-Response Relationship, Drug; Humans; Laser Coagulation; Macular Degeneration; Mice; Mice, Inbred C57BL; Middle Aged; Neovascularization, Physiologic; Oxidation-Reduction; Pigment Epithelium of Eye; Pyrroles; Rats; Rats, Sprague-Dawley; Serum Albumin; Vascular Endothelial Growth Factor A

2006
Oxidative damage-induced inflammation initiates age-related macular degeneration.
    Nature medicine, 2008, Volume: 14, Issue:2

    Topics: Aging; Animals; Antibodies; Antigens; Bruch Membrane; Complement C3d; Immunization; Inflammation; Macular Degeneration; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Oxidative Stress; Pigment Epithelium of Eye; Protein Transport; Pyrroles; Time Factors; Titrimetry

2008