Compounds > pyrroles
Page last updated: 2024-08-18

pyrroles and Long QT Syndrome

pyrroles has been researched along with Long QT Syndrome in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (50.00)24.3611
2020's3 (50.00)2.80

Authors

AuthorsStudies
Kobayashi, F; Mendell, J; Shimizu, T1
Boinpally, R; Borbridge, L; Butler, M; McGeeney, D; McNamee, B; Periclou, A; Yao, L1
Cheung, SYA; Cullberg, M; Delff, P; Dota, C; Maroj, B; Parkinson, J; Rekić, D; Schiavon, G; Voronova, V1
Chi, W; Ferber, G; Jackson, J; Janku, F; Li, BT; Mendzelevski, B; Sager, PT; Sullivan, RJ; Welsch, D; Weng, O1
Cui, W; Liu, F; Lu, JC; Pei, WN; Xie, RQ; Yang, C1
Chan, G; Krishnaswami, S; Kudlacz, E; Wang, R1

Trials

6 trial(s) available for pyrroles and Long QT Syndrome

ArticleYear
Randomized, Double-Blind, Single-Dose, Placebo-Controlled Crossover Study to Evaluate the Effects of Esaxerenone on QTc Interval in Healthy Subjects.
    Clinical pharmacology in drug development, 2020, Volume: 9, Issue:6

    Topics: Adult; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Female; Humans; Long QT Syndrome; Male; Mineralocorticoid Receptor Antagonists; Moxifloxacin; Pyrroles; Sulfones; Young Adult

2020
A Single Supratherapeutic Dose of Atogepant Does Not Affect Cardiac Repolarization in Healthy Adults: Results From a Randomized, Single-Dose, Phase 1 Crossover Trial.
    Clinical pharmacology in drug development, 2021, Volume: 10, Issue:9

    Topics: Adolescent; Adult; Area Under Curve; Calcitonin Gene-Related Peptide Receptor Antagonists; Cross-Over Studies; Double-Blind Method; Electrocardiography; Female; Humans; Long QT Syndrome; Male; Moxifloxacin; Piperidines; Pyridines; Pyrroles; Spiro Compounds; Young Adult

2021
Concentration-QT modelling shows no evidence of clinically significant QT interval prolongation with capivasertib at expected therapeutic concentrations.
    British journal of clinical pharmacology, 2022, Volume: 88, Issue:2

    Topics: Dose-Response Relationship, Drug; Electrocardiography; Heart Rate; Humans; Long QT Syndrome; Neoplasms; Pyrimidines; Pyrroles

2022
Effect of ulixertinib, a novel ERK1/2 inhibitor, on the QT/QTc interval in patients with advanced solid tumor malignancies.
    Cancer chemotherapy and pharmacology, 2018, Volume: 81, Issue:6

    Topics: Aged; Aminopyridines; Dose-Response Relationship, Drug; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Long QT Syndrome; Male; Middle Aged; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasms; Protein Kinase Inhibitors; Pyrroles

2018
Statin therapy shortens QTc, QTcd, and improves cardiac function in patients with chronic heart failure.
    International journal of cardiology, 2010, Apr-15, Volume: 140, Issue:2

    Topics: Atorvastatin; Chronic Disease; Electrocardiography; Heart Failure; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Long QT Syndrome; Pyrroles; Treatment Outcome; Ventricular Function, Left

2010
A supratherapeutic dose of the Janus kinase inhibitor tasocitinib (CP-690,550) does not prolong QTc interval in healthy participants.
    Journal of clinical pharmacology, 2011, Volume: 51, Issue:9

    Topics: Adult; Cross-Over Studies; Double-Blind Method; Female; Follow-Up Studies; Heart Rate; Humans; Janus Kinase 3; Long QT Syndrome; Male; Middle Aged; Piperidines; Pyrimidines; Pyrroles; Systole; Young Adult

2011