Page last updated: 2024-08-18

pyrroles and Koch's Disease

pyrroles has been researched along with Koch's Disease in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.17)18.7374
1990's0 (0.00)18.2507
2000's2 (8.33)29.6817
2010's18 (75.00)24.3611
2020's3 (12.50)2.80

Authors

AuthorsStudies
Altwegg, R; Charpy, F; Debourdeau, A1
Abebe, M; Abozen, T; Alabanza, PL; Ameni, G; Aseffa, A; Balcha, TT; Baric, RS; Belay, M; Berg, S; Brown, AJ; Chandran, A; Cohen, MS; Coombs, RW; Degli-Angeli, EJ; Demaret, J; Dong, C; Dragavon, JA; Duke, ER; Eltayeb, O; Eron, JJ; Fang, L; Fischer, WA; Forrest, S; Goecker, EA; Harris, KA; Hong, S; Hudgens, MG; Huggett, JF; Jolliffe, DA; Jones, GM; Keys, J; Krajewski, TJ; Li, B; Li, L; Loftis, AJ; Manwandu, H; Martineau, AR; Martineau, HM; Mayito, J; Mollan, KR; Morse, CG; Nikolayevskyy, V; Noursadeghi, M; O'Sullivan, DM; Painter, W; Premkumar, L; Reece, ST; Sheahan, TP; Shuang, S; Szewczyk, LJ; Tayachew, D; Tegegn, M; Tirfie, EA; Tulu, B; Vordermeier, M; Wang, Q; Wang, X; Wohl, DA; Wolfe, CR; Won, JJ; Younis, S; Zewude, A1
Karkara, BB; Kumar, A; Panda, G1
Alfonso, S; Ballell, L; Barros Aguirre, D; Bates, RH; Biava, M; Cocozza, M; Consalvi, S; De Logu, A; Fernandez-Menendez, R; Poce, G; Venditti, G; Vistoli, G1
An, Q; Chen, L; Ju, Y; Liu, P; Luo, Y; Sang, Z; Tang, Y; Yang, T; Yang, Y; Zhang, T1
Deng, W; Sun, L; Wu, Q; Zhang, Z1
Agus, E; Alfonso, S; Ballell, L; Bates, RH; Biava, M; Botta, M; Cocozza, M; De Logu, A; De Rossi, E; Franzblau, SG; La Rosa, V; Manetti, F; Ortega, F; Pasca, MR; Poce, G; Porretta, GC; Rullas, J; Wae, B1
Ballante, F; Biava, M; Costi, R; De Vita, D; Di Santo, R; Feroci, M; Friggeri, L; Manetti, F; Musmuca, I; Ragno, R; Scipione, L; Tortorella, S1
Aminabhavi, TM; Gadad, AK; Joshi, SD; Kulkarni, VH; More, UA; Nadagouda, MN1
Carmona, L; Gomez-Reino, JJ; Maneiro, JR; Salgado, E; Souto, A1
Aminabhavi, TM; Joshi, SD; Koli, D; Kulkarni, MS; More, UA; Nadagouda, MN1
Cole, ST; Conroy, TM; Hartkoorn, RC; Huszár, S; Kazakova, E; Kolly, GS; Makarov, V; Mikušová, K; Neres, J; Piton, J; Ryabova, OB; Šarkan, M; Vocat, A1
Cardiel, MH; Gomez-Reino, JJ; Gul, A; Kwok, K; Lukic, T; Mortensen, E; Park, SH; Ponce de Leon, D; Riese, R; Tanaka, Y; Valdez, H; Winthrop, KL1
Dorhoi, A1
Ahidjo, BA; Bishai, WR; Bougoudogo, F; Cheung, L; Lun, S; Maiga, M; Maiga, MC; Pelly, S1
Arista, L; Boyle, GA; Brunschwig, C; Chibale, K; de Kock, C; Gessner, RK; Lawrence, N; Manjunatha, UH; Moosa, A; Njoroge, M; Rao, SP; Seldon, R; Sirgel, F; Smith, PW; Soares de Melo, C; Street, LJ; Taylor, D; van der Westhuyzen, R; van Helden, P; Warner, DF; Wilson, CR; Winks, S1
Charles-Schoeman, C; Cohen, SB; Curtis, JR; DeMasi, R; Geier, J; Kwok, K; Lee, EB; Mariette, X; Nash, P; Riese, R; Tanaka, Y; Thirunavukkarasu, K; Wang, L; Winthrop, KL; Wollenhaupt, J1
Biava, M; Botta, M; De Logu, A; De Rossi, E; Manetti, F; Meleddu, R; Poce, G; Porretta, GC1
Alfonso, S; Battilocchio, C; Biava, M; Botta, M; de Logu, A; Manetti, F; Poce, G; Porretta, GC1
Aung, H; Hirsch, CS; Toossi, Z; Wu, M1
Ammerman, NC; Bishai, WR; Guo, H; Lun, S; Maiga, M; Winglee, K1
Anbarasu, A; Jha, DK; Lavanya, P; Panda, L; Ramaiah, S1
JENEY, E; ZSOLNAI, T1

Reviews

6 review(s) available for pyrroles and Koch's Disease

ArticleYear
Novel candidates in the clinical development pipeline for TB drug development and their synthetic approaches.
    Chemical biology & drug design, 2021, Volume: 98, Issue:5

    Topics: Adamantane; Animals; Antitubercular Agents; DNA Gyrase; Drug Development; Enzyme Inhibitors; Humans; Isonicotinic Acids; Mycobacterium tuberculosis; Oxazolidinones; Piperidines; Pyrroles; Structure-Activity Relationship; Tuberculosis; Tuberculosis, Multidrug-Resistant; Uridine

2021
Tuberculosis, hepatitis B and herpes zoster in tofacitinib-treated patients with rheumatoid arthritis.
    Immunotherapy, 2019, Volume: 11, Issue:4

    Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Asia, Eastern; Drug Therapy, Combination; Herpes Zoster; Herpesvirus 3, Human; Humans; Mycobacterium tuberculosis; Piperidines; Prevalence; Pyrimidines; Pyrroles; Recurrence; Risk; Tuberculosis; Virus Activation

2019
Risk of tuberculosis in patients with chronic immune-mediated inflammatory diseases treated with biologics and tofacitinib: a systematic review and meta-analysis of randomized controlled trials and long-term extension studies.
    Rheumatology (Oxford, England), 2014, Volume: 53, Issue:10

    Topics: Biological Products; Humans; Incidence; Latent Tuberculosis; Piperidines; Pyrimidines; Pyrroles; Risk; Tuberculosis

2014
Tuberculosis and other opportunistic infections in tofacitinib-treated patients with rheumatoid arthritis.
    Annals of the rheumatic diseases, 2016, Volume: 75, Issue:6

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Humans; Immunocompromised Host; Immunosuppressive Agents; Incidence; Janus Kinase 3; Opportunistic Infections; Piperidines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Risk Assessment; Tuberculosis

2016
Developing pyrrole-derived antimycobacterial agents: a rational lead optimization approach.
    ChemMedChem, 2011, Apr-04, Volume: 6, Issue:4

    Topics: Animals; Antitubercular Agents; Drug Design; Humans; Mycobacterium tuberculosis; Pyrroles; Structure-Activity Relationship; Tuberculosis

2011
LL-3858.
    Tuberculosis (Edinburgh, Scotland), 2008, Volume: 88, Issue:2

    Topics: Animals; Antitubercular Agents; Humans; Isonicotinic Acids; Pyrroles; Treatment Outcome; Tuberculosis

2008

Other Studies

18 other study(ies) available for pyrroles and Koch's Disease

ArticleYear
Disseminated Tuberculosis in a Patient Treated with Tofacitinib for Ulcerative Colitis.
    Journal of Crohn's & colitis, 2022, 05-10, Volume: 16, Issue:4

    Topics: Colitis, Ulcerative; Humans; Piperidines; Pyrimidines; Pyrroles; Tuberculosis

2022
    The Lancet. Microbe, 2021, Volume: 2, Issue:6

    Topics: Cross-Sectional Studies; DNA; Ethiopia; HeLa Cells; HIV Infections; Humans; Hydrogen Peroxide; Isoniazid; Latent Tuberculosis; Leukocytes, Mononuclear; Manganese Compounds; Methylene Blue; Microscopy, Confocal; Mycobacterium tuberculosis; Nanocomposites; Nanoparticles; Neoplasms; Oxides; Photochemotherapy; Photosensitizing Agents; Photothermal Therapy; Polyethylene Glycols; Polymers; Prospective Studies; Pyrroles; Tuberculin Test; Tuberculosis; Tumor Microenvironment

2021
In vivo potent BM635 analogue with improved drug-like properties.
    European journal of medicinal chemistry, 2018, Feb-10, Volume: 145

    Topics: Animals; Antitubercular Agents; Cell Proliferation; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Hep G2 Cells; Humans; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Pyrroles; Structure-Activity Relationship; Tuberculosis

2018
Design, synthesis and biological evaluation of novel pyrrole derivatives as potential ClpP1P2 inhibitor against Mycobacterium tuberculosis.
    Bioorganic chemistry, 2018, Volume: 80

    Topics: Antitubercular Agents; Bacterial Proteins; Drug Design; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Pyrroles; Serine Endopeptidases; Tuberculosis

2018
Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Animals; Antibiotics, Antitubercular; Bacterial Proteins; Cell Line; Female; Humans; Mice; Microbial Sensitivity Tests; Microsomes; Mycobacterium tuberculosis; Piperazines; Pyrroles; Tuberculosis

2013
Pharmacophore assessment through 3-D QSAR: evaluation of the predictive ability on new derivatives by the application on a series of antitubercular agents.
    Journal of chemical information and modeling, 2013, Jun-24, Volume: 53, Issue:6

    Topics: Antitubercular Agents; Drug Design; Humans; Models, Molecular; Mycobacterium tuberculosis; Oxazolidinones; Pyrroles; Quantitative Structure-Activity Relationship; Tuberculosis

2013
Design, synthesis, molecular docking and 3D-QSAR studies of potent inhibitors of enoyl-acyl carrier protein reductase as potential antimycobacterial agents.
    European journal of medicinal chemistry, 2014, Volume: 71

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Drug Design; Humans; Hydrazones; Ligands; Molecular Docking Simulation; Mycobacterium tuberculosis; Oxidoreductases; Pyrroles; Quantitative Structure-Activity Relationship; Tuberculosis

2014
Synthesis, evaluation and in silico molecular modeling of pyrroyl-1,3,4-thiadiazole inhibitors of InhA.
    Bioorganic chemistry, 2015, Volume: 59

    Topics: Antitubercular Agents; Bacterial Proteins; Drug Design; Humans; Models, Molecular; Mycobacterium tuberculosis; Oxidoreductases; Pyrroles; Quantitative Structure-Activity Relationship; Thiadiazoles; Tuberculosis

2015
The 8-Pyrrole-Benzothiazinones Are Noncovalent Inhibitors of DprE1 from Mycobacterium tuberculosis.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:8

    Topics: Alcohol Oxidoreductases; Animals; Antitubercular Agents; Bacterial Proteins; Catalytic Domain; Disease Models, Animal; Hep G2 Cells; Humans; Male; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Piperazines; Pyridines; Pyrroles; Spiro Compounds; Structure-Activity Relationship; Thiazines; Tuberculosis

2015
Suppress for Success: A JAK Inhibitor for Adjunct Therapy of Tuberculosis.
    EBioMedicine, 2015, Volume: 2, Issue:8

    Topics: Animals; Female; Humans; Piperidines; Pyrimidines; Pyrroles; Tuberculosis

2015
Efficacy of Adjunctive Tofacitinib Therapy in Mouse Models of Tuberculosis.
    EBioMedicine, 2015, Volume: 2, Issue:8

    Topics: Animals; Cytokines; Disease Models, Animal; Female; Humans; Mice; Mice, Inbred BALB C; Piperidines; Pyrimidines; Pyrroles; Tuberculosis

2015
Pyrrolo[3,4-c]pyridine-1,3(2H)-diones: A Novel Antimycobacterial Class Targeting Mycobacterial Respiration.
    Journal of medicinal chemistry, 2015, Dec-10, Volume: 58, Issue:23

    Topics: Animals; Antitubercular Agents; Electron Transport Complex III; Humans; Mice; Microsomes, Liver; Molecular Targeted Therapy; Mycobacterium tuberculosis; Pyridones; Pyrroles; Rats; Tuberculosis

2015
Long-term safety of tofacitinib for the treatment of rheumatoid arthritis up to 8.5 years: integrated analysis of data from the global clinical trials.
    Annals of the rheumatic diseases, 2017, Volume: 76, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Herpes Zoster; Humans; Immunocompromised Host; Incidence; Infections; Male; Middle Aged; Neoplasms; Opportunistic Infections; Piperidines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Time Factors; Tuberculosis; Young Adult

2017
1,5-Diaryl-2-ethyl pyrrole derivatives as antimycobacterial agents: design, synthesis, and microbiological evaluation.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Models, Molecular; Mycobacterium tuberculosis; Pyrroles; Quantitative Structure-Activity Relationship; Tuberculosis; Vero Cells

2009
Inhibition of Mycobacterium tuberculosis-induced signalling by transforming growth factor-β in human mononuclear phagocytes.
    Scandinavian journal of immunology, 2012, Volume: 75, Issue:3

    Topics: Benzamides; Dioxoles; Humans; Isoquinolines; Leukocytes, Mononuclear; Mycobacterium tuberculosis; Phagocytes; Plasminogen Activators; Plasminogen Inactivators; Pyridines; Pyrroles; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta; Tuberculosis

2012
Risk of tuberculosis reactivation with tofacitinib (CP-690550).
    The Journal of infectious diseases, 2012, Volume: 205, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Immunologic Factors; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Piperidines; Pyrimidines; Pyrroles; Tuberculosis

2012
Detection and confirmation of alkaloids in leaves of Justicia adhatoda and bioinformatics approach to elicit its anti-tuberculosis activity.
    Applied biochemistry and biotechnology, 2012, Volume: 168, Issue:5

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Alkaloids; Antitubercular Agents; Computational Biology; Fatty Acid Synthase, Type II; Humans; Justicia; Molecular Docking Simulation; Mycobacterium tuberculosis; Plant Leaves; Pyrroles; Quinazolines; Tuberculosis

2012
[Search for new tuberculostatics. V. N-aryl derivatives of o-dicarboxylic acid imides].
    Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. 1. Abt. Medizinisch-hygienische Bakteriologie, Virusforschung und Parasitologie. Originale, 1959, Volume: 175, Issue:1-2

    Topics: Dicarboxylic Acids; Imides; Maleates; Mycobacterium tuberculosis; Pregnenes; Pyrroles; Succinates; Tuberculosis

1959