pyrroles has been researched along with Innate Inflammatory Response in 340 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (4.12) | 18.7374 |
| 1990's | 9 (2.65) | 18.2507 |
| 2000's | 113 (33.24) | 29.6817 |
| 2010's | 174 (51.18) | 24.3611 |
| 2020's | 30 (8.82) | 2.80 |
| Authors | Studies |
|---|---|
| Feng, Y; Li, Y; Liu, L; Liu, X; Liu, Y; Wang, L; Wu, Q; Zhang, L | 1 |
| Green, A; Huang, J; Johnson, J; Saigal, R; Smith, C; Walter, M; Yap, N | 1 |
| Chen, C; Chen, J; Chen, Z; Deng, Y; Guo, H; Huang, H; Li, G; Liu, J; Liu, N; Sai, X; Sun, T; Wang, X; Yu, C; Zhao, M; Zheng, Y; Zhu, P; Zhu, S; Zhuang, J | 1 |
| Allen, CNS; Arjona, SP; Ghaleb, LJ; Herzi, M; Llewellyn, MD; Santerre, M; Sawaya, BE; Shcherbik, N | 1 |
| Alarifi, S; Gautam, N; Mohseen, M; Pal, AK; Palanivel, H; Prabhu, SV; Saxena, M | 1 |
| Kihara, S; Yamamoto, H; Yoshida, N | 1 |
| Appel, D; Hummel, R; Klein, M; Li, S; Ritter, K; Schäfer, MKE; Strehle, J; Tegeder, I; Wang, Y; Wernersbach, I | 1 |
| Isomäki, P; Kuuliala, A; Kuuliala, K; Leirisalo-Repo, M; Palmroth, M; Peltomaa, R; Silvennoinen, O; Valli, A; Vidqvist, KL; Virtanen, A | 1 |
| Bingham, CO; Brault, Y; Dougados, M; Fallon, L; Kessouri, M; Roychoudhury, S; Taylor, PC; Wang, L | 1 |
| Anzini, M; Brogi, S; Cappelli, A; Chelini, A; Chemi, G; Di Capua, A; Di Cesare Mannelli, L; Ghelardini, C; Giorgi, G; Giuliani, G; Grillo, A; La Motta, C; Lucarini, E; Pace, S; Paolino, M; Reale, A; Rossi, A; Sautebin, L; Valoti, M | 1 |
| Heo, JD; Jeong, EJ; Kim, NH; Kim, YN; Lee, S; Lee, SM; Rho, JR | 1 |
| Balansky, R; De Flora, S; Izzotti, A; La Maestra, S; Micale, RT; Pulliero, A | 1 |
| Kato, M; Kimura, N; Kubo, K; Mabe, K; Matsuda, S; Tsuda, M | 1 |
| Chu, FF; Doroshow, JH; Esworthy, RS; Gao, Q; Shen, B | 1 |
| Abdalla, AN; Abourehab, MAS; Ahmed, M; Aslam, A; Attalah, KM; ElSawy, NA; Gouda, AM | 1 |
| Angiari, S; Kane, H; Kelly, B; Mills, KHG; O'Neill, LAJ; Palsson-McDermott, EM; Papadopoulou, G; Pearce, EL; Rana, N; Runtsch, MC; Sutton, CE | 1 |
| Li, B; Li, C; Qiu, X; Song, C; Wang, L; Wang, Q; Wen, F; Xing, MMQ; Xiong, W; Xu, K; Zhang, X | 1 |
| Crapser, JD; Green, KN; Ochaba, J; Reidling, JC; Soni, N; Thompson, LM | 1 |
| Boeckmans, J; Buyl, K; De Kock, J; M Rodrigues, R; Natale, A; Rogiers, V; Rombaut, M; Vanhaecke, T | 1 |
| Aguirre, AJ; Almonte, C; Bonneau, R; Bulatovic, M; Castro, DM; Chen, T; Christensen, CL; Deng, J; Diskin, B; Donaghue, J; Dowling, CM; Dries, R; Freeman, GJ; Gray, NS; Hammerman, PS; Han, H; He, Z; Huang, Q; Jani, K; Kaelin, WG; Kersbergen, A; Kwiatkowski, N; Labbe, KE; Leggett, A; Li, F; Li, S; Miller, G; Oser, MG; Pan, Y; Papadopoulos, E; Pyon, V; Quinn, M; Rabin, AR; Ranieri, M; Rothenberg, E; Silver, H; Sundberg, B; Sutherland, KD; Sviderskiy, VO; Thakurdin, C; Velcheti, V; Wang, ES; Wong, KK; Yang, A; Yin, Y; Yuan, GC; Zhang, H; Zhang, T; Zhang, X | 1 |
| Coleman, LG; Crews, FT; Zou, J | 1 |
| Chen, FH; Chernikov, OV; Chiu, HW; Fang, Z; Gan, CH; Hsieh, CY; Hsu, CH; Hua, KF; Ju, TC; Lam, Y; Li, LH; Liu, ML; Rao, YK; Wong, WT | 1 |
| Chin, J; Cho, SJ; Choi, H; Kim, GJ; Lee, SB; Maharjan, S; Nam, JW | 1 |
| Brazina, S; Clark, D; Hsieh, CL; Hu, D; Marcucio, R; Miclau, T; Nakamura, MC; Niemi, EC; Yang, F | 1 |
| El-Kashef, DH; Makled, MN | 1 |
| Kim, H; Kim, SJ; Lee, D | 1 |
| Armuzzi, A; Colombel, JF; Farnier, M; Friedman, GS; Ha, C; Kwok, K; Quirk, D; Salese, L; Sands, BE; Su, C; Taub, PR | 1 |
| Fang, J; Lin, J; Liu, Z; Lu, X; Ron, Z; Zeng, R; Zeng, W | 1 |
| Rolev, KD; Shu, XS; Ying, Y | 1 |
| Hossain, A; Imamura, T; Jahan, N; Kitada, K; Kobara, H; Kosaka, S; Masaki, T; Nakano, D; Nishiyama, A; Ohsaki, H; Rahman, A; Sawano, T; Sen, A | 1 |
| Abdel-Wahab, O; Bradley, RK; Cho, H; Chow, A; Chowell, D; Cui, D; De Neef, E; Diaz, LA; Durham, BH; Elhanati, Y; Erickson, C; Gabel, AM; Ghosh, A; Gigoux, M; Greenbaum, B; Hogg, SJ; Jin, J; Knorr, DA; Liu, J; Lu, B; Lu, SX; Merghoub, T; Molina, H; Rhodes, MC; Rousseau, B; Sabio, E; Shah, H; Shen, Y; Singer, M; Taylor, RE; Thomas, JD; Wang, E; Wolchok, JD; Xie, A; Zamarin, D | 1 |
| Díaz Valle, D; García Caride, S; Marquina, G | 1 |
| Ge, G; Liu, X; Wang, Q; Xia, J; Xu, F; Xu, X; Yang, Y; Zhang, W; Zhao, S | 1 |
| Amano, W; Hayashi, M; Kakimoto, K; Katsuda, Y; Kimoto, Y; Konishi, N; Shinozaki, Y; Taniai-Riya, E; Tanimoto, A; Toyoda, K; Yamamoto, Y | 1 |
| Barrish, JC; Carter, PH; Duan, JJ; Fura, A; Gillooly, K; Hynes, J; Jiang, B; Kempson, J; Khan, JA; Lippy, JS; Lu, Z; McIntyre, K; Nadler, SG; Pitt, S; Pitts, WJ; Sack, JS; Salter-Cid, LM; Schieven, GL; Shen, G; Stachura, S; Tokarski, JS; Wrobleski, ST; Wu, H; Zhang, RF | 1 |
| Gao, GM; Jiang, DB; Kan, QC; Li, YM; Liu, SY; Xu, PH; Zhang, LL; Zheng, XL; Zheng, ZH | 1 |
| Barrasa, JI; Gratal, P; Herrero-Beaumont, G; Largo, R; Larrañaga-Vera, A; Pérez-Baos, S; Prieto-Potin, I | 1 |
| Kaur, G; Silakari, O | 1 |
| Poorvashree, J; Suneela, D | 1 |
| Berstein, G; Correa-da Rosa, J; Fitz, LJ; Garcet, S; Kim, J; Krueger, JG; Lee, J; Lowes, MA; Suarez-Farinas, M; Tomalin, L; Valdez, H; Wolk, R | 1 |
| Breault, DT; Carlone, DL; Deary, L; Ediger, T; Richmond, CA; Rickner, H; Shah, MS; Tovaglieri, A; Zhou, F | 1 |
| Li, H; Yu, SJ | 1 |
| Gaikwad, AN; Goand, UK; Gupta, A; Gupta, S; Kumar, D; Rajan, S; Shankar, K; Srivastava, A; Srivastava, AK; Varshney, S; Vishwakarma, AL | 1 |
| Chen, X; Jia, XK; Kuang, YH; Liao, LQ; Liu, YK; Lu, Y; Qin, QS; Wu, LS; Zhou, XC; Zhu, W | 1 |
| Canter, RG; Dominique, MA; Fang, TC; Khan, T; Lee, VM; Miller, KR; Ransohoff, RM; Restrepo, CR; Roberts, CJ; Spiller, KJ; Trojanowski, JQ | 1 |
| Lu, P; Wang, Y; Xia, Y; Yuan, X; Zhong, Y; Zhu, L | 1 |
| Banovic, F; Blubaugh, A; Denley, T; Eguiluz-Hernandez, S; Elder, D; Rissi, D | 1 |
| Ji, X; Li, J; Liu, Y; Tan, R; Wang, H; Wang, L; Wu, Z; Zhang, Y; Zhong, X; Zhu, M | 1 |
| Garofalo, A; Grande, F; Ioele, G; Occhiuzzi, MA; Ragno, G | 1 |
| Cho, H; Choy, EH; Hashizume, M; John, MR; O'Mahony, A | 1 |
| Cao, J; Chen, K; Shou, J; Su, SB; Sun, R; Yang, J; Yang, T; Zhang, S; Zhao, M | 1 |
| Bochkov, YA; Foster, MW; Que, LG; Voelker, DR; Yang, Z | 1 |
| Wang, Y; Xia, Y; Yuan, X; Zhu, L | 1 |
| Bijev, AT; Kostadinov, I; Vladimirova, S; Zlatanova, H | 1 |
| Hayashi, M; Kim, Y; Nakashima, T; Ono, T; Takayanagi, H; Yoda, T | 1 |
| Choy, EH | 1 |
| Berve, K; Groh, J; Klein, D; Martini, R; West, BL | 1 |
| Bai, P; Fu, J; He, Y; Jia, D; Lyu, A; Lyu, L; Wan, N; Wan, Q; Yu, T; Zuo, C | 1 |
| Eichele, DD; Lele, SM; Wang, D; Wei, X; Wu, J; Yang, L; Zhang, F; Zhao, G | 1 |
| Bianchi, D; Harcken, C; Nabozny, G; Scholl, P; Thomson, D | 1 |
| Hua, J; Liu, L; Wang, C; Wang, J; Wang, Y; Xie, X; Xu, W; Yan, Y; Yang, Z; Yi, T | 1 |
| Brahmaroutu, A; DeMorrow, S; Frampton, G; Grant, S; Jefferson, B; McMillin, M; Petrescu, AD; Thomas, A; Williams, E | 1 |
| An, D; Chen, A; Chen, L; Du, Y; Li, Y; Sha, S; Wang, Z; Wu, C; Xu, W; Zhou, L; Zhu, Y | 1 |
| Ducruet, AF; Lawton, MT; Qiu, S; Sheth, KN; Shi, E; Shi, K | 1 |
| Bonelli, M; Dalwigk, K; Hayer, S; Holinka, J; Karonitsch, T; Kiener, HP; Niederreiter, B; Olmos Calvo, I; Pap, T; Platzer, A; Sevelda, F; Smolen, JS; Steiner, G; Superti-Furga, G | 1 |
| Jing, LM; Li, H; Liu, HL; Luo, JP; Shen, ZQ; Yang, SL; Yang, Y | 1 |
| Artis, DR; Bollag, G; Bremer, R; Burton, EA; Carias, H; Habets, G; Hirth, P; Hurt, CR; Ibrahim, PN; Lin, P; Marimuthu, A; Matusow, B; Nespi, M; Nguyen, H; Nolop, K; Oh, A; Powell, B; Shellooe, R; Spevak, W; Tesch, GH; Tsang, G; West, BL; Wu, G; Zhang, C; Zhang, J; Zhang, KY; Zhang, Y | 1 |
| Aguirre, AC; Amaral, JB; Barbosa, SP; Bianco, HT; Fonseca, FA; França, CN; Izar, MC; Lins, LC; Matos, LN; Santana, JM | 1 |
| Banach, M; Bielecka-Dabrowa, A; Mikhailidis, DP; Rizzo, M; Rysz, J; von Haehling, S | 1 |
| Das, DK; Das, N; Dey, S; Kesh, SB; Khan, A; Manna, K; Sikder, K | 1 |
| Ballet, S; Bini, J; Corot, C; Dickson, SD; Fayad, ZA; Izquierdo-Garcia, D; Klink, A; Lancelot, E; Mateo de Castro, J; Millon, A; Robert, P | 1 |
| Brodowski, K; Jaworski, K; Kosior, DA; Krzykwa, A; Opolski, G; Zylińska, E | 1 |
| Abdelbaky, A; Alon, A; Beals, CR; Dansky, H; Farkouh, ME; Fayad, ZA; Klimas, MT; Mogg, R; Nunes, IO; Rudd, JH; Shankar, SS; Subramanian, SS; Tawakol, A | 1 |
| Gerber, BL | 1 |
| Dong, QT; Gao, RL; Geng, YJ; Gersh, BJ; He, ZX; Lu, MJ; Qian, HY; Qiao, SB; Shen, R; Song, L; Yang, YJ; Zhao, SH | 1 |
| Gitirana, LB; Machado, MN; Magalhães, CB; Melo, AC; Porto, LC; Ribeiro, ML; Santos, JC; Valença, SS; Zin, WA | 1 |
| Barbieri, J; Dewhurst, S; Gantz Marker, MA; Gelbard, HA; Goodfellow, VS; Loweth, CJ; Lu, SM; Marker, DF; Muly, EC; Puccini, JM; Tremblay, MÈ | 1 |
| Cieśla-Dul, M; Potaczek, DP; Undas, A; Żółciński, M | 1 |
| Lappegård, KT; Pop, G; Pop-Purceleanu, M; Sexton, J; Tendolkar, I; van Heerde, W | 1 |
| Medvedeva, EA; Seleznev, EI; Shchukin, IuV | 1 |
| Arch, RH; Atkinson, MA; Bluestone, JA; Brekken, RA; Calderon, B; Kabre, B; Kubeck, S; Lang, J; Pullen, N; Szot, GL; Villalta, SA; Wasserfall, C | 1 |
| Chahal, N; Manlhiot, C; McCrindle, BW; Niedra, E; Yeung, RS | 1 |
| Kawalec, P; Mikrut, A; Pilc, A; Wiśniewska, N | 1 |
| Do e, Z; Fukumoto, Y; Kanazawa, M; Matsumoto, Y; Sato, A; Satoh, K; Shimizu, T; Shimokawa, H; Takahashi, K | 1 |
| Briolant, S; Desgrouas, C; Dormoi, J; Pascual, A; Pradines, B; Travaillé, C | 1 |
| Meirer, K; Proschak, E; Steinhilber, D | 1 |
| Alon, A; Emami, H; Farkouh, M; Fayad, ZA; Fifer, KM; Rudd, JHF; Shankar, SS; Singh, P; Subramanian, S; Tawakol, A; Van Dyke, TE; Vijayakumar, J; Vucic, E | 1 |
| Tremoulet, AH | 1 |
| Manlhiot, C; McCrindle, BW | 1 |
| Athyros, VG; Karagiannis, A; Katsiki, N; Mikhailidis, DP | 1 |
| Alves, Mdo S; de Araújo Júnior, RF; de Araújo, AA; de Moura, LM; de Souza, LB; Rocha, HO; Souza, TO; Torres, KP | 1 |
| Gadina, M; Ghoreschi, K | 1 |
| Chen, Y; Huang, A; Ku, H; Li, LC; Li, Q; Moorhead, JF; Powis, SH; Ruan, XZ; Varghese, Z; Wheeler, DC; Zhao, L | 1 |
| Abdallah, FR; Aldohmy, S; Elseweidy, MM; Kassem, HM; Younis, NN | 1 |
| Baglietto-Vargas, D; Bitner, RS; Castello, NA; Cheng, D; Decker, MW; Esbenshade, TA; Green, KN; Kitazawa, M; LaFerla, FM; Medeiros, R | 1 |
| Blonder, JP; Boyanapalli, R; Delany, C; Green, LH; Look, K; Looker, D; Mehra, NK; Mutka, SC; Qiu, J; Richards, JP; Rosenthal, GJ; Scoggin, C; Sun, X; Suniga, M | 1 |
| Emoto, N; Hirata, K; Nakayama, K; Suzuki, Y; Van Hung, T; Vignon-Zellweger, N; Yagi, K | 1 |
| Clark, JD; Flanagan, ME; Telliez, JB | 1 |
| Aoki, Y; Mizoguchi, H; Sakurada, S; Sakurada, T; Takeda, K; Watanabe, C | 1 |
| He, GX; Liu, XL; Xu, HP; Zhao, XJ | 1 |
| So, A; Varisco, PA | 1 |
| Alhussaini, AA; Cool, CD; Farkas, D; Farkas, L; Kraskauskas, D; Kraskauskiene, V; Natarajan, R; Nicolls, MR | 1 |
| Chen, J; Cui, W; Jiang, R; Li, T; Quan, W; Tian, Y; Wang, D; Wang, Y; Yu, H; Zhang, J; Zhou, L | 1 |
| Anticoli, S; Gambardella, L; Malorni, W; Maselli, A; Matarrese, P; Panusa, A; Ruggieri, A; Vona, R | 1 |
| Koh, KK | 1 |
| Emami, H; Farkouh, M; Fayad, ZA; Fifer, K; Rudd, JH; Subramanian, S; Tawakol, A; Van Dyke, T | 1 |
| Armstrong, AJ; Chen, I; Chow-Maneval, E; Clarke, SJ; Lechuga, M; Michaelson, MD; Paolini, J; Pond, GR; Smith, MR; Sonpavde, G; Templeton, AJ; Vardy, JL; Wang, SL | 1 |
| Azushima, K; Dejima, T; Kanaoka, T; Kobayashi, R; Maeda, A; Ohsawa, M; Tamura, K; Toya, Y; Umemura, S; Uneda, K; Wakui, H | 1 |
| Cai, J; Ding, X; Fang, Y; Liu, S; Liu, T; Yu, X; Zhang, B; Zhang, H | 1 |
| Chen, Y; Li, Q; Moorhead, JF; Powis, SH; Ruan, XZ; Varghese, Z; Wheeler, DC; Zhao, L | 1 |
| Caporale, R; Clemente, AM; Filippelli, A; Gelli, AM; Guasti, D; Musilli, C; Paccosi, S; Parenti, A; Romagnoli, P; Torcia, MG | 1 |
| Boy, MG; Hutmacher, MM; Isaacs, JD; Kowalski, K; Krishnaswami, S; Lan, S; Menon, S; Nduaka, C; Riese, R; Zuckerman, A | 1 |
| Chen, Y; Chen, Z; Gu, M; Lin, Y; Luo, N; Wang, J; Wang, X | 1 |
| Ahmadi, M; Bacot, S; Barone-Rochette, G; Broisat, A; Devoogdt, N; Dumas, LS; Fagret, D; Ghezzi, C; Lahoutte, T; Perret, P; Riou, LM; Slimani, L; Soubies, A; Toczek, J | 1 |
| Cruz-Guilloty, F; Duffort, S; Ivanov, D; Laird, JM; Perez, VL; Saeed, AM; Salomon, RG; Wang, H | 1 |
| Dostal, E; Gaspar, L; Goliasch, G; Hofbauer, SL; Huber, K; Kastl, SP; Katsaros, KM; Krychtiuk, KA; Maurer, G; Oravec, S; Pfaffenberger, S; Pongratz, T; Speidl, WS; Wojta, J; Wonnerth, A | 1 |
| Bespalova, ID; Kaliuzhin, VV; Mediantsev, IuA; Murashev, BIu; Osikhov, IA; Riazantseva, NV | 1 |
| Guan, Y; Guo, HY; Shan, ZL; Wang, YT; Yuan, HT; Zhang, Y | 1 |
| Emery, P | 1 |
| Cooray, SN; Gobbetti, T; Jonassen, TE; Montero-Melendez, T; Perretti, M | 1 |
| Hu, J; Huang, L; Li, B; Lu, X; Peng, Z; Qin, J; Yang, X; Ye, K; Yuan, F; Zhang, Y | 1 |
| Bonnet, C; Sibon, I | 1 |
| Abdelbaky, A; Ballantyne, CM; Du, S; Ehlgen, A; Emami, H; Farkouh, ME; Farmer, M; Fayad, ZA; Hayes, W; Kim, J; Langenickel, TH; Li, L; Mohler, ER; Roth, E; Subramanian, S; Tawakol, A; Velasquez, L; Vucic, E | 1 |
| Akalin Çiftçi, G; Akalin, A; Alataş, İÖ; Ertorun, İ; Musmul, A | 1 |
| Tanaka, Y | 1 |
| Bäumer, W; Cook, E; Ehling, S; Fukuyama, T | 1 |
| Graepel, R; Lopes, F; McDougall, JJ; McKay, DM; Petri, B; Reyes, JL; Sharkey, KA; Wang, A | 1 |
| Alpini, G; Kumar, N; Meng, F; Mishra, J; Verma, RK | 1 |
| Dervan, PB; Kang, JS | 1 |
| Hayama, T; Kamio, N; Matsushima, K; Muromachi, K; Okabe, T | 1 |
| Banzato, A; Basso, U; Brunello, A; Diminutto, A; Fiduccia, P; Maruzzo, M; Roma, A; Zagonel, V; Zattoni, F; Zustovich, F | 1 |
| Di Lernia, V | 1 |
| Gröters, S; Hofmann, T; Landsiedel, R; Ma-Hock, L; Neubauer, N; Rey Moreno, M; Strauss, V; Teubner, W; Treumann, S; van Ravenzwaay, B; Veith, U; Wiench, K; Wohlleben, W | 1 |
| Baier, F; Bise, T; de Preux Charles, AS; Jaźwińska, A; Marro, J | 1 |
| Feng, DY; Li, WY; Luo, MC; Wang, HY; Xiao, J; Xu, CD; Zhou, SY; Zhou, T | 1 |
| Amano, W; Kabashima, K; Matsushita, M; Miyachi, Y; Nakajima, S; Tanimoto, A; Yamamoto, Y | 1 |
| Avila-Campos, MJ; Corrêa, RO; Lancellotti, M; Rodrigues, HG; Sernaglia, EM; Vieira, A; Vieira, AT; Vinolo, MAR | 1 |
| Calama, E; Carreño, C; De Alba, J; Domènech, A; Miralpeix, M; Prats, N; Ramis, I | 1 |
| Dejaco, C; Fasching, P; Fessler, J; Graninger, W; Stradner, M | 1 |
| Abria, C; Raychaudhuri, SK; Raychaudhuri, SP | 1 |
| Fearon, U; Gao, W; McGarry, T; Veale, DJ | 1 |
| Brullo, C; Fallacara, AL; Grossi, G; Musumeci, F; Sanna, M; Schenone, S | 1 |
| Lee, JK; Singh, AK; Singh, I; Won, JS | 1 |
| Chandra, N; Mateen, AA; Naidu, MU; Raju, YS; Usharani, P | 1 |
| Devaraj, S; Jialal, I; Siegel, D; Singh, U | 1 |
| Fukudo, S; Hasegawa, R; Ito, H; Nagura, Y; Saito-Nakaya, K | 1 |
| Drechsler, C; Krane, V; Lilienthal, J; März, W; Wanner, C; Winkler, K | 2 |
| Blanco-Colio, LM; de Teresa, E; Egido, J; Farsang, C; Gaw, A; Gensini, G; Langer, A; Leiter, LA; Martín-Ventura, JL; Martineau, P | 2 |
| Hoeger, KM | 1 |
| Amato, M; Arquati, M; Baldassarre, D; Brusoni, B; Camera, M; Cortellaro, M; Fiorentini, C; Montorsi, P; Porta, B; Romano, S; Tremoli, E; Veglia, F | 1 |
| Chen, Y; Cheng, X; Ding, Y; Liao, M; Liao, YH; Tang, T; Wang, M; Xia, C; Xie, J; Yao, R; Yu, X | 1 |
| Barderas, MG; Dardé, VM; De la Cuesta, F; Egido, J; Jiménez-Nácher, JJ; López-Bescós, L; Tarín, N; Tuñón, J; Vivanco, F | 1 |
| Amano, A; Daida, H; Kajimoto, K; Kasai, T; Kojima, Y; Miyauchi, K; Niinami, H; Shimada, A; Shimada, K | 1 |
| Briley-Saebo, KC; Fayad, ZA; Mani, V; Razzouk, L | 1 |
| Boyle, JR; Brown, AP; Gaunt, ME; Gillard, JH; Graves, MJ; Hayes, PD; Howarth, SP; Kirkpatrick, PJ; Li, ZY; Miller, SR; Patterson, AJ; Tang, TY; U-King-Im, JM; Varty, K; Walsh, SR; Warburton, EA; Zalewski, A | 1 |
| DU, Q; Huang, M; Liu, X; Yao, X; Yin, KS | 1 |
| Fraley, AE; Ganz, P; Kinlay, S; Libby, P; Olsson, AG; Rifai, N; Schwartz, GG; Szarek, M; Tsimikas, S; Witztum, JL | 1 |
| Kitas, GD; Melas, N; Saratzis, A; Saratzis, N | 1 |
| Barreiro, EJ; Fraga, CA; Mendes, TC; Nascimento-Junior, NM; Raimundo, JM; Sudo, RT; Zapata-Sudo, G | 1 |
| Jin, R; Liu, M; Wang, F; Wang, Y | 1 |
| Chen, P; Gan, Y; Li, G; Wu, S; Xing, X; Zhang, J; Zhang, Y; Zhao, S | 1 |
| Aigbirhio, FI; Bird, JL; Davenport, AP; Davies, JR; Figg, N; Fryer, TD; Izquierdo-Garcia, D; Richards, HK; Rudd, JH; Warburton, EA; Weissberg, PL | 1 |
| Choi, EJ; Choi, JP; Gho, YS; Hong, SW; Jeon, SG; Kim, YK; Kim, YS; Moon, HG; Oh, SY; Shin, TS; Zhu, Z | 1 |
| Andrade, SP; Araújo, FA; Mendes, JB; Rocha, MA | 1 |
| Aikawa, E; Figueiredo, JL; Hembrador, S; Keliher, E; Kelly, K; Libby, P; Nahrendorf, M; Panizzi, P; Weissleder, R; Zhang, H | 1 |
| Grover, RK; Rao, PN | 1 |
| Frisbee, JC; Frisbee, SJ; Goodwill, AG; James, ME; Stapleton, PA | 1 |
| Kumar, VL; Wahane, VD | 1 |
| Adánez, G; Ayala, I; Castells, MT; Martín-Castillo, A; Pérez, BG; Polo, MT | 1 |
| Antoniades, C; Charakida, M; Kamboli, AM; Koniari, K; Marinou, K; Miliou, A; Nikolopoulou, A; Noutsou, M; Papageorgiou, N; Siasos, G; Stefanadi, E; Stefanadis, C; Tousoulis, D | 1 |
| Buchetti, B; Carnovale, A; Fallarino, M; Filetti, S; Gatti, A; Lenti, L; Lococo, E; Mandosi, E; Morano, S; Rossetti, M | 1 |
| Cengiz, SD; Dünder, I; Kaya, C; Pabuccu, R | 1 |
| Barber, MJ; Chasman, DI; Chatterjee, A; Hyde, CL; Krauss, RM; Li, X; Mangravite, LM; McCarty, CA; Nickerson, DA; Ridker, PM; Rieder, MJ; Rotter, JI; Smith, JD; Stephens, M; Wilke, RA; Williams, PT | 1 |
| Feng, L; Jiang, J; Li, M; Ren, H; Zhang, Y; Zhu, X | 1 |
| Cairns, R; Cannon, CP; Michael Gibson, C; Nazer, B; Ray, KK | 1 |
| Borggrefe, M; Dempfle, CE; Hoffmeister, HM; Lang, S; Suselbeck, T; Swoboda, S; Szabo, S; Walter, T | 1 |
| Cummons, T; Harrison, JE; Hummel, M; Kennedy, JD; Lu, P; Mark, L; Whiteside, GT | 1 |
| Joo, IW; Oh, HJ; Ryu, JH | 1 |
| Di Sciascio, G; Melfi, R; Nusca, A; Patti, G | 1 |
| Gong, F; Gong, Q; Gu, H; Jin, X; Li, X; Yin, H; Yuan, B; Zhang, B; Zheng, F; Zhu, J | 1 |
| Baer, A; Ky, B; Millar, JS; Pruscino, L; Rader, DJ; Wolfe, ML | 1 |
| Bergheanu, SC; Dallinga-Thie, GM; Hattori, H; Karalis, IK; Liem, AH; van Tol, A; Wolterbeek, R; Wouter Jukema, J | 1 |
| Barrish, JC; Dodd, JH; Doweyko, AM; Dyckman, AJ; Gillooly, KM; Hynes, J; Kiefer, SE; Kish, KF; Leftheris, K; Li, T; Lin, J; Lin, S; Liu, C; Marathe, PH; McIntyre, KW; McKinnon, M; Newitt, JA; Pitt, S; Sack, JS; Salter-Cid, L; Schieven, GL; Shen, DR; Shuster, DJ; Wityak, J; Wrobleski, ST; Wu, H; Zhang, H; Zhang, RF | 1 |
| Bentz, K; Eick, C; Kettering, K; Laszlo, R; Menzel, KA; Schreieck, J; Schreiner, B | 1 |
| Sun, RP; Yang, L; Yin, P; Zhou, HY | 1 |
| Borden, EC; Byzova, TV; Kerr, BA; Malinin, NL; Merkulova, AA; Podrez, EA; Salomon, RG; Tischenko, M; West, XZ | 1 |
| Melfi, R; Nusca, A; Patti, G; Sciascio, GD | 1 |
| Harward, ML; Jones, MA; Joyce, CJ; Kostner, KM; Kruger, PS; Roberts, MS; Venkatesh, B | 1 |
| Haron, MM; Houssen, ME; Ibrahim, TM; Metwally, SS | 1 |
| El-Barbary, AM; Hamouda, HE; Hussein, MS; Ismail, RG; Rageh, EM; Wagih, AA | 1 |
| Arndt, JW; Biamonte, MA; Giza, K; Harning, EK; Kehry, MR; Li, P; Luchetti, D; Lundgren, K; Manning, A; Rabah, D; Shi, J; Yun, TJ | 1 |
| Demers, LM; Hogeman, CS; Kunselman, AR; Legro, RS; Raja-Khan, N; Stetter, CM | 1 |
| Gulati, P; Venkataramanan, R; Vijayakrishnan, L | 1 |
| Cámara, C; Costo, A; Crespo, L; Fernández Pereira, L; Pereira, G; Sánchez Muñoz-Torrero, JF | 1 |
| Calisto, KL; Camacho, AC; Carvalheira, JB; Carvalho, Bde M; Guadagnini, D; Mittestainer, FC; Ropelle, ER; Saad, MJ | 1 |
| Barsoum, FF | 1 |
| Chang, H; Jin, X; Qi, Z; Wang, Y; Zou, J | 1 |
| Abdel Rahman, MN; Abdelmotelb, AA | 1 |
| Bancells, C; Benítez, S; Ordóñez-Llanos, J; Pérez, A; Sánchez-Quesada, JL; Wägner, AM | 1 |
| Bi, H; Chen, WA; Daugherty, A; Hong, B; Luo, Y; Wang, JA; Wang, Y; Xie, X; Zhang, S | 1 |
| An, LM; Chang, WT; Chen, IJ; Lin, HL; Shen, KP; Wu, BN | 1 |
| Baiuomy, AR; Elmegeed, GA; Eskander, EF; Mohareb, RM; William, MG | 1 |
| Asakawa, M; Chiba, K; Kawasumi, M; Kobayashi, T; Miyamoto, T; Mori, T; Morioka, H; Toyama, Y; Yoshida, H; Yoshimura, A | 1 |
| He, B; Hu, LH; Jing, Q; Pu, J; Shao, Q; Shen, LH | 1 |
| Bash, D; Cavender, MA; Hislop, C; Kastelein, JJ; Nicholls, SJ; Rosenson, RS; Schwartz, G; Waters, DD | 1 |
| Saito, Y | 1 |
| Fabian, J; Griessbach, K; Hanekamp, W; Lehr, M; Wiegard, A | 1 |
| Bao, W; Benessiano, J; Mallat, Z; Olsson, AG; Ryu, SK; Schwartz, GG; Tedgui, A; Tsimikas, S | 1 |
| Bostock, GD; Vizcaychipi, MP | 1 |
| Cho, YW; Lee, JY; Lee, KT; Noh, YS; Shin, JS; Yoo, MS | 1 |
| Alberti, PF; Conti, V; Corazzi, T; Falcinelli, E; Gresele, P; Miglietta, D; Minuz, P; Momi, S; Monopoli, A; Ongini, E | 1 |
| Chen, H; Wu, YJ; Xue, M | 1 |
| Bryson, GL; Neilipovitz, DT; Taljaard, M | 1 |
| Chung, YT; Li, H; Liao, J; Yan, L; Yang, AL; Yang, GY; Zhang, M; Zhang, W | 1 |
| Dai, Y; Kobayashi, K; Kogure, Y; Noguchi, K; Wan, Y; Wang, S; Yamanaka, H; Zhang, W; Zhu, W | 1 |
| Claycombe, KJ; Nair, MG; Zhou, Z | 1 |
| Abe, K; Ikeda, Y; Kozuki, M; Kurata, T; Miyazaki, K; Morimoto, N; Ohta, Y | 1 |
| Chan, C; Ivashkiv, LB; Xu, K; Yarilina, A | 1 |
| Li, W; Liu, K; Ma, A; Shao, L; Wang, J; Wang, Z; Wu, D; Zhang, P; Zhang, Y | 1 |
| Farah, R; Jubran, F; Khamisy-Farah, R | 1 |
| Deng, SB; Du, JL; Li, Q; She, Q; Xia, S | 1 |
| Cai, K; Hu, Y; Luo, Z; Xie, D | 1 |
| Dulin, JN; Grill, RJ; Karoly, ED; Strobel, HW; Wang, Y | 1 |
| Berbée, JF; Havekes, LM; Hiemstra, PS; Khedoe, PP; Mol, IM; Princen, HM; Rensen, PC; Romijn, JA; Tsikas, D; van der Hoorn, JW; van Klinken, JB; Wang, Y; Wong, MC | 1 |
| Atkin, SL; Kilpatrick, ES; Sathyapalan, T; Shepherd, J | 1 |
| Arbustini, E; Camera, M; Cofrancesco, E; Cortellaro, M; Gabrielli, L; Negri, A; Rossi, F; Tremoli, E | 1 |
| Dao, LH; Guidoin, R; Jiang, X; Marois, Y; Tessier, D; Traoré, A; Zhang, Z | 1 |
| Hamakubo, T; Itoh, T; Izumi, A; Kanke, T; Kodama, T; Mataki, C; Morikawa, S; Saito, Y; Takabe, W; Wada, Y | 1 |
| Alber, HF; Ares, MP; Dichtl, W; Dulak, J; Frick, M; Nilsson, J; Pachinger, O; Schwarzacher, SP; Weidinger, F | 1 |
| Aviles, RJ; Brennan, ML; Fu, X; Hazen, SL; Penn, MS; Shishehbor, MH; Sprecher, DL | 1 |
| Averkov, OV; Deev, AD; Gratsianskiĭ, NA; Pokrovskaia, EV; Vaulin, NA | 1 |
| Cicuttini, F; Ding, C | 1 |
| Haloui, M; Jandrot-Perrus, M; Meilhac, O; Michel, JB | 1 |
| Ganz, P; Kinlay, S; Leslie, SJ; Libby, P; Olsson, AG; Rifai, N; Sasiela, WJ; Schwartz, GG; Szarek, M | 1 |
| Caselli, A; Economides, PA; Horton, ES; Khaodhiar, L; Tiani, E; Veves, A | 1 |
| Fang, CH; Li, JJ | 1 |
| Andreassen, AK; Aukrust, P; Gullestad, L; Hognestad, A; Holm, T; Kjekshus, JK; Semb, AG; Stokke, O; Wergeland, R | 1 |
| Dao, LH; Guidoin, R; Roberge, C; Rouabhia, M; Shi, G; Wan, Y; Wang, Z; Zhang, Z | 1 |
| Akin, M; Aliyev, E; Altuglu, I; Ercan, E; Ercan, HE; Sekuri, C; Tengiz, I | 1 |
| Jono, S; Kizu, A; Koyama, H; Nishizawa, Y; Okuno, Y; Shioi, A | 1 |
| Egido, J; Tuñón, J | 1 |
| Emeis, SJ; Kleemann, R; Kooistra, T; Offerman, EH; Princen, HM; Szalai, AJ; Verschuren, L | 1 |
| Antoniades, C; Bosinakou, E; Kotsopoulou, M; Panagiotakos, D; Pitsavos, C; Stefanadis, C; Tousoulis, D; Vlachopoulos, C | 1 |
| Kulkarni, SK; Patil, CS; Singh, VP | 1 |
| Haskard, DO; Lunnon, MW; Mandryko, V; Naoumova, RP; Randi, AM; Wibaut-Berlaimont, V | 1 |
| Naveau, B | 1 |
| Assaloni, R; Ceriello, A; Da Ros, R; Esposito, K; Giugliano, D; Maier, A; Piconi, L; Quagliaro, L | 1 |
| Antoniades, C; Bosinakou, E; Katsi, V; Kotsopoulou, M; Stefanadis, C; Tousoulis, D; Tsioufis, C | 1 |
| Blanco-Colio, LM; Egido, J; Gómez-Hernández, A; Hernández, G; Martín-Ventura, JL; Muñoz-García, B; Ortega, L; Serrano, J; Tuñón, J; Vega, M | 1 |
| Dohi, Y; Ohashi, M; Sato, K; Sugiyama, M; Takase, H; Ueda, R | 1 |
| Athyros, VG; Elisaf, M; Mikhailidis, DP | 1 |
| Aso, Y; Inukai, T; Inukai, Y; Matsumoto, S; Matsutomo, R; Takebayashi, K; Wakabayashi, S | 1 |
| Annovazzi, A; Arca, M; Bonanno, E; D'Alessandria, C; De Toma, G; Marcoccia, A; Scopinaro, F; Signore, A; Spagnoli, LG; Violi, F | 1 |
| Ferns, GA; Ghayour-Mobarhan, M; Lamb, DJ; Livingstone, C; Taylor, A; Vaidya, N; Wang, T | 1 |
| Bernard, D; De Backer, G; De Bacquer, D; De Buyzere, M; De Sutter, J; Jordaens, L; Langlois, M; Matthys, K; Tavernier, R; Van de Veire, NR | 1 |
| Nosaka, S; Ueki, M; Ushiroyama, T | 1 |
| Lawler, RL; Letterer, RA; Levy, WC; McDonald, GB; Minami, E; Mozaffarian, D | 1 |
| Bayés, B; Bonet, J; Granada, ML; Lauzurica, R; Llopis, MA; Navarro, M; Pastor, MC; Romero, R | 1 |
| Day, CA; Jacob, RF; Mason, RP; Walter, MF | 1 |
| Gupta, R; Lakshmy, R; Maulik, SK; Naik, N; Narang, D; Thomas, MK | 1 |
| Deng, P; Hong, SC; Nie, S; Wu, J; Wu, ZH; Zhao, SP; Zhou, HN | 1 |
| Chow, SC; Coward, WR; Marei, A; Vasa-Nicotera, MM; Yang, A | 1 |
| Bradbury, J | 1 |
| Atkinson, S; Brown, SH; Chessell, IP; Chowdhury, A; Clayton, NM; Coleman, T; Giblin, GM; Gleave, RJ; Hall, A; Hammond, B; Healy, MP; Johnson, MR; Michel, AD; Naylor, A; Novelli, R; Spalding, DJ; Tang, SP | 1 |
| Hazen, SL; Nicholls, SJ; Nissen, SE; Ntanios, F; Schoenhagen, P; Sipahi, I; Tuzcu, EM; Wun, CC | 1 |
| Dörge, H; Grabedünkel, J; Liakopoulos, OJ; Nagorsnik, U; Schmitto, JD; Schoendube, FA | 1 |
| Busser, E; de Kleijn, DP; de Vries, JP; Koekkoek, JA; Moll, FL; Pasterkamp, G; Schoneveld, A; van der Wal, AC; Velema, E; Verheijen, JH; Verhoeven, BA; Virmani, R | 1 |
| Boudoulas, H; Stefanadi, E; Stefanadis, C; Toutouzas, K; Tsiamis, E; Tsioufis, C; Vavuranakis, M | 1 |
| Cunha, FQ; Cunha, TM; Ferreira, SH; Parada, CA; Poole, S; Santodomingo-Garzón, T; Valério, DA; Verri, WA | 1 |
| Chu, G; Ding, G; Jia, R; Tian, S | 1 |
| Ciccarelli, L; Corradi, L; Derosa, G; Fogari, E; Fogari, R; Lazzari, P; Preti, P; Zoppi, A | 1 |
| Aizawa, Y; Fukaya, H; Imaki, R; Izumi, T; Kubo, T; Ohtaki, K; Ozaki, K; Ozaki, S; Shinagawa, H | 1 |
| Cerletti, C; Dell'Elba, G; Evangelista, V; Manarini, S; Rotondo, S | 1 |
| Brady, HJ; Caldicott, A; Crescenzi, E; Dransfield, I; Duffin, R; Gray, M; Haslett, C; Martin, MC; Martinez-Losa, M; Riley, NA; Rossi, AG; Savill, JS; Sawatzky, DA; Sheldrake, TA; Walker, A; Walker, TR; Ward, C | 1 |
| Brown, SH; Chessell, IP; Chowdhury, A; Clayton, NM; Coleman, T; Giblin, GM; Hall, A; Hammond, B; Healy, MP; Johnson, MR; Metcalf, A; Michel, AD; Naylor, A; Novelli, R; Spalding, DJ; Sweeting, J | 1 |
| Abad, S; Cachofeiro, V; de Vinuesa, SG; Goicoechea, M; Gómez-Campderá, F; Lahera, V; Luño, J; Vega, A | 1 |
| Alhan, CC; Avkaroğullari, M; Cayli, M; Demir, M; Demirtaş, M; Dönmez, Y; Inal, T; Kanadaşi, M; Koç, M; San, M; Usal, A | 1 |
| Li, M; Ren, H; Zhang, Y; Zhu, X | 1 |
| Arima, J; Iguro, Y; Kariyazono, H; Masuda, H; Nakamura, K; Sakata, R; Yamada, K | 1 |
| Gans, RO; May, JF; Mulder, DJ; Smit, AJ; Tervaert, JW; van Doormaal, JJ; van Haelst, PL; Wobbes, MH; Zijlstra, F | 1 |
| Anderson, DR; Caspers, N; Kurumbail, RG; Mahoney, MW; Meyers, MJ; Mourey, RJ; Poda, GI; Reitz, DB; Schindler, JF; Vernier, WF | 1 |
| Ezhov, MV; Kukharchuk, VV; Naumov, VG; Samoĭlenko, EIu; Sergienko, IV; Tvorogova, MG | 1 |
| Dhayat, N; Dhayat, S; Du, J; Hilfiker-Kleiner, D; Laufs, U; Noutsias, M; Riad, A; Schultheiss, HP; Spillmann, F; Tschöpe, C; Van Linthout, S; Westermann, D | 1 |
| Erdogan, O; Ordulu, E | 1 |
| Adams, V; Doehner, W; Du, J; Mohr, Z; Pauschinger, M; Riad, A; Schultheiss, HP; Sobirey, M; Stiehl, S; Tschöpe, C; Westermann, D | 1 |
| Asher, J; Houston, M | 1 |
| Azzellino, A; Balestri, G; Cazzaniga, M; Cerrito, MG; Cusa, EN; DeCarlini, C; Ferrari, AU; Garducci, S; Guerra, L; Lavitrano, ML; Loardi, C; Mancia, G; Menicanti, L; Paolini, G; Radaelli, A; Santo, D | 1 |
| Amato, M; Arquati, M; Baldassarre, D; Brusoni, B; Camera, M; Cortellaro, M; Fiorentini, C; Montorsi, P; Porta, B; Romano, S; Tremoli, E | 1 |
| Abdul-Karim, FW; Dowlati, A; Duerk, J; Fu, P; Hanks, S; Hartman, P; Hoppel, C; Ivy, P; Jesberger, JA; Lewin, J; McCrae, K; Overmoyer, B; Persons, M; Radivoyevitch, T; Remick, SC; Robertson, K; Shenk, R; Silverman, P; Wasman, JK; Ziats, NP | 1 |
| Inoue, S; Kawara, A; Kimura, T; Kumakura, S; Murakami, Y; Nakao, A; Suzuki, K; Ushiyama, S; Yamada, T | 1 |
| Arroyo, V; Carmeliet, P; Fernandez-Varo, G; Friedman, SL; Jiménez, W; Morales-Ruiz, M; Muñoz-Luque, J; Rodés, J; Ros, J; Tugues, S | 1 |
| Anyakoha, NG; Barry, CE; Clarke, RM; Deighan, BF; Lynch, MA; Lyons, A; Nicolaou, A; O'Connell, F | 1 |
| Ganz, P; Kinlay, S; Libby, P; Olsson, AG; Rifai, N; Schwartz, GG; Szarek, M; Waters, DD | 1 |
| Kohno, K; Murata, Y; Sasaguri, Y; Tanimoto, A; Tsutsui, M; Wang, KY | 1 |
| Antoniades, C; Bosinakou, E; Katsi, V; Latsios, G; Marinou, K; Papageorgiou, N; Stefanadi, E; Stefanadis, C; Tousoulis, D; Triantafyllou, G; Tsioufis, C; Vavuranakis, E | 1 |
| Bonilha, VL; Hollyfield, JG; Lu, L; Perez, VL; Rayborn, ME; Salomon, RG; Shadrach, KG; Ufret, RL; Yang, X | 1 |
| Bergeron, J; Couture, P; Gagné, C; Hogue, JC; Lamarche, B; Tremblay, AJ | 1 |
| Kazantseva, MO; Logacheva, IV | 1 |
| De Angelis, S; De Lorenzo, A; Di Daniele, N; Di Renzo, L; Miani, N; Noce, A; Tozzo, C | 1 |
| Alcaino, H; Bustos, C; Castro, PF; Chiong, M; Gabrielli, LA; Garcia, L; Godoy, I; Greig, D; Lavandero, S; Mellado, R; Miranda, R; Verdejo, HE; Vukasovic, JL | 1 |
| Hashizume, H; Kamio, N; Matsushima, K; Nakao, S; Sugiya, H | 1 |
| Andalib, S; Garjani, A; Maleki-Dizaji, N; Ziaee, M | 1 |
| Ando, H; Fujimura, A; Kaneko, S; Saito, T; Sugimoto, K; Takamura, T; Tsuruoka, S; Yanagihara, H | 1 |
| Koenig, W | 1 |
| Ballantyne, CM; Davidson, MH; Hanefeld, M; Johnson, JL; Mohler, ER; Ruilope, LM; Zalewski, A | 1 |
| de Haan, W; de Vries-van der Weij, J; Gautier, T; Havekes, LM; Jukema, JW; Princen, HM; Rensen, PC; Romijn, JA; van der Hoogt, CC; van der Hoorn, JW; Westerterp, M | 1 |
| Aoki, M; Miyake, T; Morishita, R; Nishimura, M; Ogihara, T; Ohgi, S; Shiraya, S; Yoshikazu, F | 1 |
| Akalin, A; Akcar, N; Sensoy, B; Temiz, G | 1 |
| Chasseaud, LF; John, BA; Wood, SG | 1 |
| McDaniel, DH; Welton, WA | 1 |
| Handrich, L | 1 |
| Blanchard, JC; Carruette, A; Garret, C; Laduron, PM; Montier, F; Moussaoui, SM | 1 |
| Carruette, A; Garret, C; Moussaoui, S | 1 |
| Demopoulos, VJ; Rekka, E | 1 |
| Gein, VL; Kolla, WE; Popov, AV; Popova, NA | 1 |
| Chrousos, GP; Lewis, DB; Rice, KC; Torpy, DJ; Webster, EL; Zachman, EK | 1 |
| Cheah, AY; Dawood, F; Lee, JK; Liu, P; Rabinovitch, M; Saiki, Y; Wen, WH; Zaidi, SH | 1 |
| Bustos, C; Díaz, C; Egido, J; Hernández, G; Hernández-Presa, MA; Ortega, L; Ortego, M; Pérez, F; Tuñón, J | 1 |
| Bustos, C; Díaz, C; Egido, J; Hernández, G; Hernández-Presa, MA; Ortego, M; Tuñón, J | 1 |
| Camp, JP; Collier, JH; Hudson, TW; Schmidt, CE | 1 |
| Park, A | 1 |
| Dorner, GT; Joukhadar, C; Klein, N; Prinz, M; Schmetterer, L; Schrolnberger, C; Vukovich, T; Wolzt, M | 1 |
| Chrousos, GP; Coukos, G; Coutifaris, C; Gravanis, A; Kalantaridou, S; Makrigiannakis, A; Margioris, AN; Rice, KC; Zoumakis, E | 1 |
| Grip, O; Janciauskiene, S; Lindgren, S | 1 |
| Hurt-Camejo, E; Mattsson-Hultén, L; Oscarsson, J; Wiklund, O | 1 |
| Ishii, K; Motoyoshi, S; Nakamura, H; Shimizu, M; Yokoyama, Y | 1 |
| Dewijze, M; Dony, J; Stehman, M | 1 |
| Diverse, P | 1 |
| Daenens, L | 1 |
| Arrigoni-Martelli, E | 1 |
| Hirschfeld, DR; Maloney, PJ; Martinez, GR; Rosenkranz, RP; Walker, KA; Yang, DS | 1 |
| Ackerman, N; Ballaron, SA; Galeazzi, E; Greenhouse, R; Guzmán, A; Muchowski, JM; Peréz, V; Rovito, JR; Tomolonis, AJ; Young, JM | 1 |
| Ackrell, J; Cooper, GF; Halpern, O; Kluge, AF; Koehler, R; Muchowski, JM; Simon, RL; Unger, SH; Van Horn, AR; Wren, DL | 1 |
| Macmorine, DR; Movat, HZ; Takeuchi, Y | 1 |
| Reilly, MA; Schayer, RW | 1 |
| Eyre, P; Lewis, AJ; Wells, PW | 1 |
| Iizuka, Y; Tanaka, K | 1 |
23 review(s) available for pyrroles and Innate Inflammatory Response
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide | 2023 |
Anti-NASH Drug Development Hitches a Lift on PPAR Agonism.
Topics: Chalcones; Diabetes Mellitus, Type 2; Drug Development; Fatty Liver; Humans; Hypoglycemic Agents; Inflammation; Liver; Non-alcoholic Fatty Liver Disease; Peroxisome Proliferator-Activated Receptors; Phenylpropionates; Pioglitazone; Propionates; Pyrroles | 2019 |
Targeted pharmacotherapy against neurodegeneration and neuroinflammation in early diabetic retinopathy.
Topics: Anti-Inflammatory Agents; Antioxidants; Apoptosis; Astrocytes; beta Catenin; Diabetic Retinopathy; Ependymoglial Cells; Glutamic Acid; Glycogen Synthase Kinase 3 beta; Humans; Inflammation; Microglia; Mitochondria; Molecular Targeted Therapy; Neurodegenerative Diseases; Neuroglia; Neuroprotective Agents; Oxidative Stress; Pyrimidines; Pyrroles; Retinal Ganglion Cells; RNAi Therapeutics; tau Proteins | 2021 |
Multiple target-centric strategy to tame inflammation.
Topics: Cyclooxygenase Inhibitors; Humans; Inflammation; Lactones; Lipoxygenase; Lipoxygenase Inhibitors; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Pyrroles; Structure-Activity Relationship; Sulfones | 2017 |
Review of pentosidine and pyrraline in food and chemical models: formation, potential risks and determination.
Topics: Arginine; Cross-Linking Reagents; Diabetes Complications; Diabetes Mellitus; Food Analysis; Glucose; Glycation End Products, Advanced; Humans; Inflammation; Lysine; Molecular Structure; Norleucine; Pyrroles; Risk Factors; Uremia | 2018 |
Benzopyrroloxazines containing a bridgehead nitrogen atom as promising scaffolds for the achievement of biologically active agents.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antineoplastic Agents; Bacterial Infections; Chemistry Techniques, Synthetic; Drug Discovery; Humans; Inflammation; Neoplasms; Nitrogen; Oxazines; Pyrroles; Virus Diseases | 2018 |
Clinical significance of Janus Kinase inhibitor selectivity.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Azetidines; Humans; Inflammation; Janus Kinase Inhibitors; Piperidines; Purines; Pyrazoles; Pyrimidines; Pyrroles; Sulfonamides | 2019 |
Clinical profile of the functionally selective glucocorticoid receptor agonist BI 653048 in healthy male subjects.
Topics: Adult; Anti-Inflammatory Agents; Benzamides; Clinical Trials, Phase I as Topic; Glucocorticoids; Humans; Inflammation; Male; Middle Aged; Osteocalcin; Prednisolone; Pyridines; Pyrroles; Randomized Controlled Trials as Topic; Receptors, Glucocorticoid; Young Adult | 2019 |
The effectiveness of tofacitinib, a novel Janus kinase inhibitor, in the treatment of rheumatoid arthritis: a systematic review and meta-analysis.
Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Inflammation; Janus Kinases; Piperidines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Risk; Treatment Outcome; Tumor Necrosis Factor-alpha | 2013 |
Inhibitors of the arachidonic acid cascade: interfering with multiple pathways.
Topics: Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cyclooxygenase 2 Inhibitors; Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Humans; Inflammation; Lipoxygenase Inhibitors; Pain; Pyrroles | 2014 |
Jakpot! New small molecules in autoimmune and inflammatory diseases.
Topics: Animals; Autoimmune Diseases; Cytokines; Humans; Immunosuppressive Agents; Inflammation; Janus Kinases; Mice; Nitriles; Piperidines; Protein Kinase Inhibitors; Psoriasis; Pyrazoles; Pyrimidines; Pyrroles; Signal Transduction | 2014 |
Discovery and development of Janus kinase (JAK) inhibitors for inflammatory diseases.
Topics: Animals; Anti-Inflammatory Agents; Antirheumatic Agents; Autoimmune Diseases; Clinical Trials as Topic; Cytokines; Humans; Inflammation; Inflammatory Bowel Diseases; Janus Kinases; Piperidines; Protein Conformation; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Signal Transduction | 2014 |
Recent progress and perspective in JAK inhibitors for rheumatoid arthritis: from bench to bedside.
Topics: Arthritis, Rheumatoid; Humans; Inflammation; Janus Kinase 1; Janus Kinase 3; Methotrexate; Piperidines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; STAT1 Transcription Factor; Translational Research, Biomedical; Tumor Necrosis Factor-alpha | 2015 |
A sequence-specific DNA binding small molecule triggers the release of immunogenic signals and phagocytosis in a model of B-cell lymphoma.
Topics: Adenosine Triphosphate; Animals; Calreticulin; DNA; Enzyme-Linked Immunosorbent Assay; HMGB1 Protein; Humans; Imidazoles; Immunoblotting; Inflammation; K562 Cells; Luminescence; Lymphoma, B-Cell; Macrophages; Necrosis; Neoplasms; Nylons; Phagocytosis; Pyrroles; Signal Transduction; Telomere; Up-Regulation | 2015 |
Therapeutic Potential of Targeting the Th17/Treg Axis in Autoimmune Disorders.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Autoimmune Diseases; Forkhead Transcription Factors; Gene Expression Regulation; Humans; Immunologic Factors; Inflammation; Interleukin-17; Nuclear Receptor Subfamily 1, Group F, Member 3; Piperidines; Pyrimidines; Pyrroles; Signal Transduction; T-Lymphocytes, Regulatory; Th17 Cells; Ustekinumab | 2017 |
Pyrrolo[2,3-d]Pyrimidines as Kinase Inhibitors.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Drug Design; Humans; Inflammation; Molecular Docking Simulation; Neoplasms; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Structure-Activity Relationship | 2017 |
Can statins suppress the development of abdominal aortic aneurysms? A review of the current evidence.
Topics: Animals; Aortic Aneurysm, Abdominal; Atorvastatin; Blood Vessels; Cardiovascular Agents; Disease Progression; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Matrix Metalloproteinases; Models, Animal; Pyrroles; Risk Assessment; Simvastatin | 2010 |
Statin loading for acute coronary syndromes.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Anticholesteremic Agents; Atorvastatin; Biomarkers; C-Reactive Protein; Cytokines; Endothelium, Vascular; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Oxidative Stress; Preoperative Care; Pyrroles; Time Factors | 2010 |
Statin loading before percutaneous coronary intervention: proposed mechanisms and applications.
Topics: Angioplasty, Balloon, Coronary; Anticholesteremic Agents; Atorvastatin; Biomarkers, Pharmacological; Confidence Intervals; Endothelium, Vascular; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Inflammation; Kidney Diseases; Multivariate Analysis; Myocardial Infarction; Pyrimidines; Pyrroles; Risk Factors; Rosuvastatin Calcium; Sulfonamides; Time Factors | 2010 |
Treating inflammation with the Janus kinase inhibitor CP-690,550.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Autoimmune Diseases; Graft Rejection; Humans; Immunosuppressive Agents; Inflammation; Isoenzymes; Janus Kinase 3; Piperidines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Signal Transduction; STAT Transcription Factors | 2011 |
Pitavastatin: an overview.
Topics: Antioxidants; Atorvastatin; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Clinical Trials, Phase IV as Topic; Endothelium, Vascular; Hepatocytes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Inflammation; Japan; Metabolic Syndrome; Molecular Structure; Multicenter Studies as Topic; Plaque, Atherosclerotic; Pyrroles; Quinolines; Receptors, LDL | 2011 |
Licofelone (Merckle).
Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cyclooxygenase Inhibitors; Humans; Inflammation; Lipoxygenase Inhibitors; Osteoarthritis; Pyrroles; Structure-Activity Relationship | 2003 |
Statins and C-reactive protein levels.
Topics: Atorvastatin; C-Reactive Protein; Cardiovascular Diseases; Cholesterol, LDL; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Pyrroles; Risk Factors | 2007 |
78 trial(s) available for pyrroles and Innate Inflammatory Response
| Article | Year |
|---|---|
The effect of tofacitinib on residual pain in patients with rheumatoid arthritis and psoriatic arthritis.
Topics: Adalimumab; Arthritis, Psoriatic; Arthritis, Rheumatoid; Bayes Theorem; C-Reactive Protein; Humans; Inflammation; Pyrroles; Treatment Outcome | 2022 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide | 2023 |
A 12 week, randomized, double-blind, placebo-controlled clinical trial for the evaluation of the efficacy and safety of HT083 on mild osteoarthritis.
Topics: Adult; Aged; Analgesics; Animals; Anti-Inflammatory Agents; Arthralgia; Commiphora; Double-Blind Method; Female; Humans; Indoles; Inflammation; Male; Medicine, Chinese Traditional; Middle Aged; Osteoarthritis, Knee; Paeonia; Placebos; Pyrroles; Republic of Korea; Rodentia; Safety; Treatment Outcome; Visual Analog Scale | 2020 |
The Efficacy of Imrecoxib and Celecoxib in Axial Spondyloarthritis and Their Influence on Serum Dickopff-Related Protein 1 (DKK-1) Levels.
Topics: Biomarkers; Celecoxib; Demography; Follow-Up Studies; Humans; Inflammation; Intercellular Signaling Peptides and Proteins; Pyrroles; Spondylarthritis; Sulfides; Treatment Outcome | 2017 |
Reduction of Inflammatory and Cardiovascular Proteins in the Blood of Patients with Psoriasis: Differential Responses between Tofacitinib and Etanercept after 4 Weeks of Treatment.
Topics: Adult; Aged; Cardiovascular Diseases; Cytokines; Etanercept; Female; Humans; Inflammation; Male; Middle Aged; Piperidines; Protein Kinase Inhibitors; Proteomics; Psoriasis; Pyrimidines; Pyrroles; Risk Factors; Treatment Outcome; Young Adult | 2018 |
Administration of a loading dose of atorvastatin before percutaneous coronary intervention prevents inflammation and reduces myocardial injury in STEMI patients: a randomized clinical study.
Topics: Aged; Atorvastatin; C-Reactive Protein; Combined Modality Therapy; Echocardiography; Female; Heptanoic Acids; Humans; Inflammation; Male; Matrix Metalloproteinase 9; Middle Aged; Myocardial Infarction; Natriuretic Peptide, Brain; Percutaneous Coronary Intervention; Prospective Studies; Pyrroles; Ventricular Function, Left | 2013 |
Effects of ezetimibe on markers of synthesis and absorption of cholesterol in high-risk patients with elevated C-reactive protein.
Topics: Aged; Anticholesteremic Agents; Atorvastatin; Azetidines; C-Reactive Protein; Cardiovascular Diseases; Cholesterol; Desmosterol; Ezetimibe; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Middle Aged; Phytosterols; Prospective Studies; Pyrroles; Risk Factors; Sitosterols; Statistics, Nonparametric | 2013 |
The influence of atorvastatin on parameters of inflammation left ventricular function, hospitalizations and mortality in patients with dilated cardiomyopathy--5-year follow-up.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Atorvastatin; Cardiomyopathy, Dilated; Cytokines; Female; Follow-Up Studies; Heptanoic Acids; Hospitalization; Humans; Inflammation; Male; Middle Aged; Pyrroles; Uric Acid; Ventricular Function, Left | 2013 |
Intensification of statin therapy results in a rapid reduction in atherosclerotic inflammation: results of a multicenter fluorodeoxyglucose-positron emission tomography/computed tomography feasibility study.
Topics: Adult; Aged; Aged, 80 and over; Aorta, Thoracic; Atherosclerosis; Atorvastatin; Carotid Arteries; Double-Blind Method; Feasibility Studies; Female; Fluorodeoxyglucose F18; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Middle Aged; Multimodal Imaging; Plaque, Atherosclerotic; Positron-Emission Tomography; Pyrroles; Treatment Outcome | 2013 |
[Prevention of cardiovascular complications in patients undergoing aortic-iliac reconstructions by correction of inflammation and endotoxemia].
Topics: Aorta, Abdominal; Atherosclerosis; Atorvastatin; Cardiovascular Diseases; Dose-Response Relationship, Drug; Endotoxemia; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Iliac Artery; Inflammation; Middle Aged; Postoperative Complications; Pyrroles; Treatment Outcome; Vascular Surgical Procedures | 2013 |
High-dose atorvastatin reduces periodontal inflammation: a novel pleiotropic effect of statins.
Topics: Adult; Aged; Aged, 80 and over; Atorvastatin; Double-Blind Method; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Middle Aged; Periodontal Diseases; Pyrroles; Treatment Outcome | 2013 |
Prognostic impact of the neutrophil-to-lymphocyte ratio in men with metastatic castration-resistant prostate cancer.
Topics: Adult; Aged; Aged, 80 and over; Alkaline Phosphatase; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Docetaxel; Hemoglobins; Humans; Indoles; Inflammation; Kaplan-Meier Estimate; L-Lactate Dehydrogenase; Lymphocyte Count; Lymphocytes; Male; Middle Aged; Neutrophils; Placebos; Prednisone; Prognosis; Proportional Hazards Models; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Pyrroles; Retrospective Studies; Sunitinib; Taxoids | 2014 |
Changes in serum creatinine in patients with active rheumatoid arthritis treated with tofacitinib: results from clinical trials.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; C-Reactive Protein; Creatinine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Inflammation; Male; Middle Aged; Piperidines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles | 2014 |
The effect of BMS-582949, a P38 mitogen-activated protein kinase (P38 MAPK) inhibitor on arterial inflammation: a multicenter FDG-PET trial.
Topics: Aged; Anti-Inflammatory Agents; Aortic Diseases; Atherosclerosis; Atorvastatin; Biomarkers; C-Reactive Protein; Carotid Artery Diseases; Double-Blind Method; Female; Fluorodeoxyglucose F18; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Inflammation Mediators; Male; Middle Aged; Multimodal Imaging; p38 Mitogen-Activated Protein Kinases; Plaque, Atherosclerotic; Positron-Emission Tomography; Predictive Value of Tests; Protein Kinase Inhibitors; Pyrroles; Radiopharmaceuticals; Time Factors; Tomography, X-Ray Computed; Treatment Outcome; Triazines; United States | 2015 |
Effect of NCB-02, atorvastatin and placebo on endothelial function, oxidative stress and inflammatory markers in patients with type 2 diabetes mellitus: a randomized, parallel-group, placebo-controlled, 8-week study.
Topics: Adrenergic beta-Agonists; Adult; Albuterol; Atorvastatin; Biomarkers; Blood Glucose; Cholesterol; Curcumin; Diabetes Mellitus, Type 2; Double-Blind Method; Endothelium, Vascular; Female; Glycated Hemoglobin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Middle Aged; Oxidative Stress; Pyrroles; Triglycerides | 2008 |
Comparison effect of atorvastatin (10 versus 80 mg) on biomarkers of inflammation and oxidative stress in subjects with metabolic syndrome.
Topics: Anticholesteremic Agents; Atorvastatin; Biomarkers; C-Reactive Protein; Dose-Response Relationship, Drug; F2-Isoprostanes; Female; Heptanoic Acids; Humans; Inflammation; Male; Matrix Metalloproteinase 9; Metabolic Syndrome; Middle Aged; Monocytes; NF-kappa B; Oxidative Stress; Polyethylene; Pyrroles; Superoxides; Tyrosine | 2008 |
Effect of atorvastatin on inflammation and outcome in patients with type 2 diabetes mellitus on hemodialysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Atorvastatin; C-Reactive Protein; Cause of Death; Diabetes Mellitus, Type 2; Heptanoic Acids; Humans; Inflammation; Middle Aged; Placebos; Predictive Value of Tests; Pyrroles; Renal Dialysis; Survival Rate; Treatment Outcome; Young Adult | 2008 |
Atorvastatin decreases elevated soluble CD40L in subjects at high cardiovascular risk. Atorvastatin on inflammatory markers study: a substudy of ACTFAST.
Topics: Aged; Anticholesteremic Agents; Atorvastatin; Biomarkers; C-Reactive Protein; CD40 Ligand; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Dose-Response Relationship, Drug; Female; Heptanoic Acids; Humans; Inflammation; Longitudinal Studies; Male; Middle Aged; Prospective Studies; Pyrroles; Risk Factors; Triglycerides | 2008 |
Markers of inflammation, thrombosis and endothelial activation correlate with carotid IMT regression in stable coronary disease after atorvastatin treatment.
Topics: Aged; Atherosclerosis; Atorvastatin; Biomarkers; Blood Coagulation; Carotid Artery Diseases; Coronary Disease; Cross-Sectional Studies; Endothelium, Vascular; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Lipids; Male; Middle Aged; Myocardial Infarction; Plasma; Pyrroles; Sample Size; Thrombosis; Ultrasonography | 2009 |
Atorvastatin modifies the protein profile of circulating human monocytes after an acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aged; Anticholesteremic Agents; Atorvastatin; Chi-Square Distribution; Dose-Response Relationship, Drug; Electrophoresis, Gel, Two-Dimensional; Female; Gene Expression; Gene Expression Profiling; Heat-Shock Proteins; Heptanoic Acids; Humans; Inflammation; Lipids; Male; Middle Aged; Monocytes; Pyrroles; Statistics, Nonparametric; Tandem Mass Spectrometry; Thrombosis | 2009 |
Short-term 20-mg atorvastatin therapy reduces key inflammatory factors including c-Jun N-terminal kinase and dendritic cells and matrix metalloproteinase expression in human abdominal aortic aneurysmal wall.
Topics: Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; Atorvastatin; Cell Proliferation; Dendritic Cells; Female; Heptanoic Acids; Humans; Inflammation; JNK Mitogen-Activated Protein Kinases; Male; Matrix Metalloproteinases; Middle Aged; Muscle, Smooth, Vascular; Pyrroles; Tissue Inhibitor of Metalloproteinase-1 | 2009 |
The ATHEROMA (Atorvastatin Therapy: Effects on Reduction of Macrophage Activity) Study. Evaluation using ultrasmall superparamagnetic iron oxide-enhanced magnetic resonance imaging in carotid disease.
Topics: Aged; Anticholesteremic Agents; Atorvastatin; Biomarkers; Carotid Arteries; Carotid Stenosis; Contrast Media; Dextrans; Double-Blind Method; Female; Ferrosoferric Oxide; Heptanoic Acids; Humans; Inflammation; Iron; Macrophages; Magnetic Resonance Imaging; Magnetite Nanoparticles; Male; Middle Aged; Nanoparticles; Oxides; Pyrroles | 2009 |
Relationship of oxidized phospholipids and biomarkers of oxidized low-density lipoprotein with cardiovascular risk factors, inflammatory biomarkers, and effect of statin therapy in patients with acute coronary syndromes: Results from the MIRACL (Myocardia
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Anticholesteremic Agents; Apolipoproteins B; Atorvastatin; Autoantibodies; Biomarkers; Cholesterol, LDL; Cohort Studies; Female; Heptanoic Acids; Humans; Immunoglobulin G; Immunoglobulin M; Inflammation; Lipoprotein(a); Male; Middle Aged; Oxidation-Reduction; Phospholipids; Pyrroles; Reactive Oxygen Species; Risk Factors; Thromboembolism | 2009 |
Atorvastatin improves endothelial function and cardiac performance in patients with dilated cardiomyopathy: the role of inflammation.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Atorvastatin; Cardiomyopathy, Dilated; Cholesterol; Double-Blind Method; Endothelium, Vascular; Exercise; Exercise Test; Female; Heart Function Tests; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Intercellular Adhesion Molecule-1; Male; Middle Aged; Myocardial Contraction; Prospective Studies; Pyrroles; Vasodilation; Ventricular Function, Left; Young Adult | 2009 |
Association of LDL cholesterol and inflammation with cardiovascular events and mortality in hemodialysis patients with type 2 diabetes mellitus.
Topics: Aged; Anticholesteremic Agents; Atorvastatin; Cardiovascular Diseases; Cholesterol, LDL; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Heptanoic Acids; Humans; Inflammation; Male; Prospective Studies; Pyrroles; Renal Dialysis | 2009 |
Combined effects of atorvastatin and metformin on glucose-induced variations of inflammatory process in patients with diabetes mellitus.
Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; Blood Glucose; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hypoglycemic Agents; Inflammation; Male; Metformin; Middle Aged; Pyrroles; Treatment Outcome; Tumor Necrosis Factor-alpha | 2011 |
Comparison of the effects of atorvastatin and simvastatin in women with polycystic ovary syndrome: A prospective, randomized study.
Topics: Adult; Atorvastatin; C-Reactive Protein; Fasting; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperandrogenism; Inflammation; Insulin; Insulin Resistance; Luteinizing Hormone; Oxidative Stress; Polycystic Ovary Syndrome; Prospective Studies; Pyrroles; Simvastatin; Testosterone; Young Adult | 2010 |
Genome-wide association of lipid-lowering response to statins in combined study populations.
Topics: Adult; Aged; Atorvastatin; Bayes Theorem; Cholesterol; Female; Genome-Wide Association Study; Genotype; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Lipids; Male; Middle Aged; Phenotype; Polymorphism, Single Nucleotide; Pravastatin; Pyrroles; Simvastatin | 2010 |
Association between percutaneous coronary intervention and long-term C-reactive protein levels in patients with acute coronary syndromes.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Atherosclerosis; Atorvastatin; C-Reactive Protein; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Middle Aged; Observation; Pravastatin; Pyrroles; Treatment Outcome | 2010 |
Short-term treatment with high-dose atorvastatin reduces LDL cholesterol but shows no anti-inflammatory effects in normolipidemic subjects with normal CRP levels.
Topics: Adult; Anticholesteremic Agents; Apolipoproteins; Atorvastatin; Biomarkers; C-Reactive Protein; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Dose-Response Relationship, Drug; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Inflammation; Leukocytes; Male; Middle Aged; Pyrroles; Young Adult | 2010 |
Effect of increasing doses of Rosuvastatin and Atorvastatin on apolipoproteins, enzymes and lipid transfer proteins involved in lipoprotein metabolism and inflammatory parameters.
Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Apolipoproteins; Atorvastatin; Carrier Proteins; Dose-Response Relationship, Drug; Enzymes; Female; Fluorobenzenes; Heptanoic Acids; Humans; Inflammation; Lipid Metabolism; Lipoproteins; Male; Maximum Tolerated Dose; Middle Aged; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Sulfonamides | 2010 |
Continuation of statin therapy in patients with presumed infection: a randomized controlled trial.
Topics: Aged; Aged, 80 and over; Atorvastatin; C-Reactive Protein; Cholesterol; Disease Progression; Double-Blind Method; Drug Administration Schedule; Female; Heptanoic Acids; Hospital Mortality; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Interleukin-6; Male; Middle Aged; Prospective Studies; Pyrroles; Sepsis; Severity of Illness Index; Treatment Outcome | 2011 |
Effect of atorvastatin on inflammation and modification of vascular risk factors in rheumatoid arthritis.
Topics: Adiponectin; Adult; Aged; Analysis of Variance; Antirheumatic Agents; Arthritis, Rheumatoid; Atorvastatin; Drug Therapy, Combination; Endothelium, Vascular; Female; Forearm; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Lipids; Male; Methotrexate; Middle Aged; Prednisone; Pyrroles; Regional Blood Flow; Resistin; Risk Factors; Severity of Illness Index; Tumor Necrosis Factor-alpha | 2011 |
Effects of atorvastatin on vascular function, inflammation, and androgens in women with polycystic ovary syndrome: a double-blind, randomized, placebo-controlled trial.
Topics: Adult; Androgens; Anticholesteremic Agents; Atorvastatin; Blood Vessels; Double-Blind Method; Female; Heptanoic Acids; Humans; Inflammation; Placebos; Polycystic Ovary Syndrome; Pregnancy; Pyrroles; Young Adult | 2011 |
Effect of statin and fibrate treatment on inflammation in type 2 diabetes. A randomized, cross-over study.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Aged; Atorvastatin; C-Reactive Protein; Cross-Over Studies; Diabetes Mellitus, Type 2; Female; Fibric Acids; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Middle Aged; Phospholipases A2; Phospholipases A2, Secretory; Pyrroles | 2011 |
Inhibition of secretory phospholipase A(2) in patients with acute coronary syndromes: rationale and design of the vascular inflammation suppression to treat acute coronary syndrome for 16 weeks (VISTA-16) trial.
Topics: Acetates; Acute Coronary Syndrome; Atorvastatin; Double-Blind Method; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Inflammation; Keto Acids; Phospholipases A2, Secretory; Pyrroles | 2012 |
STAR VaS--Short Term Atorvastatin Regime for Vasculopathic Subjects: a randomized placebo-controlled trial evaluating perioperative atorvastatin therapy in noncardiac surgery.
Topics: Aged; Aged, 80 and over; Atorvastatin; C-Reactive Protein; Cardiovascular Diseases; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Middle Aged; Perioperative Care; Postoperative Complications; Pyrroles; Risk Factors; Surgical Procedures, Operative | 2012 |
Impact of intensive statin use on the level of inflammation and platelet activation in stable angina after percutaneous coronary intervention: a clinical study.
Topics: Aged; Angina Pectoris; Animals; Anti-Inflammatory Agents, Non-Steroidal; Atorvastatin; Endothelium, Vascular; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Inflammation Mediators; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation Inhibitors; Premedication; Prospective Studies; Pyrroles; Reoperation; Single-Blind Method; Stents | 2013 |
Atorvastatin and thrombogenicity of the carotid atherosclerotic plaque: the ATROCAP study.
Topics: Aged; Anticholesteremic Agents; Atorvastatin; Carotid Artery Diseases; Double-Blind Method; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Lipoproteins; Macrophages; Male; Middle Aged; Prospective Studies; Pyrroles; Thromboplastin; Thrombosis | 2002 |
Statins promote potent systemic antioxidant effects through specific inflammatory pathways.
Topics: Antioxidants; Arteriosclerosis; Atorvastatin; Biomarkers; C-Reactive Protein; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Inflammation; Lipoproteins; Male; Middle Aged; Oxidation-Reduction; Prospective Studies; Pyrroles; Reactive Oxygen Species; Signal Transduction; Statistics, Nonparametric; Tyrosine | 2003 |
[Markers of inflammation and platelet aggregation in patients with non ST elevation acute coronary syndrome treated with atorvastatin or pravastatin].
Topics: Acute Disease; Adult; Aged; Anticholesteremic Agents; Atorvastatin; C-Reactive Protein; Coronary Disease; Drug Administration Schedule; Electrocardiography; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Inflammation; Male; Middle Aged; Platelet Aggregation; Pravastatin; Pyrroles; Time Factors | 2003 |
High-dose atorvastatin enhances the decline in inflammatory markers in patients with acute coronary syndromes in the MIRACL study.
Topics: Acute Disease; Aged; Angina, Unstable; Apolipoproteins; Atorvastatin; Biomarkers; C-Reactive Protein; Cholesterol, LDL; Double-Blind Method; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Interleukin-6; Male; Middle Aged; Myocardial Infarction; Pyrroles; Serum Amyloid A Protein; Syndrome; Troponin | 2003 |
The effects of atorvastatin on endothelial function in diabetic patients and subjects at risk for type 2 diabetes.
Topics: Adult; Atorvastatin; Biomarkers; Brachial Artery; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Double-Blind Method; Endothelium, Vascular; Female; Forearm; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Microcirculation; Middle Aged; Nitroglycerin; Pyrroles; Regional Blood Flow; Risk Factors; Skin; Vasodilation; Vasodilator Agents | 2004 |
Effects of conventional and aggressive statin treatment on markers of endothelial function and inflammation.
Topics: Arteriosclerosis; Atorvastatin; C-Reactive Protein; Chronic Disease; Coronary Artery Disease; E-Selectin; Female; Fibrinogen; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Middle Aged; Nitric Oxide; Pyrroles; Simvastatin; Treatment Outcome | 2004 |
Atorvastatin treatment decreases inflammatory and proteolytic activity in patients with hypercholesterolemia.
Topics: Adult; Anticholesteremic Agents; Atorvastatin; Biomarkers; C-Reactive Protein; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Inflammation; Male; Matrix Metalloproteinase 9; Middle Aged; Prospective Studies; Pyrroles; Treatment Outcome | 2004 |
Effects of atorvastatin on reactive hyperemia and inflammatory process in patients with congestive heart failure.
Topics: Aged; Anticholesteremic Agents; Atorvastatin; Biomarkers; Cytokines; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Forearm; Heart Failure; Heptanoic Acids; Humans; Hyperemia; Inflammation; Male; Middle Aged; Pyrroles; Regional Blood Flow; Vascular Cell Adhesion Molecule-1 | 2005 |
Effect of atorvastatin and irbesartan, alone and in combination, on postprandial endothelial dysfunction, oxidative stress, and inflammation in type 2 diabetic patients.
Topics: Anticholesteremic Agents; Atorvastatin; Biphenyl Compounds; Case-Control Studies; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Endothelium, Vascular; Female; Heptanoic Acids; Humans; Hyperglycemia; Hypertriglyceridemia; Inflammation; Irbesartan; Male; Middle Aged; Oxidative Stress; Postprandial Period; Pyrroles; Tetrazoles; Treatment Outcome | 2005 |
The impact of early administration of low-dose atorvastatin treatment on inflammatory process, in patients with unstable angina and low cholesterol level.
Topics: Angina, Unstable; Anticholesteremic Agents; Atorvastatin; Chemokine CCL2; Cholesterol; Female; Heptanoic Acids; Humans; Inflammation; Interleukin-6; Male; Middle Aged; Prospective Studies; Pyrroles; Time Factors; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2006 |
Intensive treatment with atorvastatin reduces inflammation in mononuclear cells and human atherosclerotic lesions in one month.
Topics: Aged; Anti-Inflammatory Agents; Atherosclerosis; Atorvastatin; Blotting, Southern; Blotting, Western; Carotid Arteries; Chemokine CCL2; Cyclooxygenase 2; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Image Processing, Computer-Assisted; Immunohistochemistry; Inflammation; Leukocytes, Mononuclear; Lipids; Male; Middle Aged; NF-kappa B; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2005 |
Inflammatory markers and the metabolic syndrome.
Topics: Antihypertensive Agents; Atorvastatin; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Drug Therapy, Combination; Fenofibrate; Fibrinogen; Heptanoic Acids; Humans; Hypolipidemic Agents; Inflammation; Lactones; Leukocyte Count; Metabolic Syndrome; Metformin; Orlistat; Prospective Studies; Pyrroles; Treatment Outcome | 2005 |
The effect of low-dose atorvastatin on circulating monocyte chemoattractant protein-1 in patients with type 2 diabetes complicated by hyperlipidemia.
Topics: Adult; Aged; Atorvastatin; C-Reactive Protein; Chemokine CCL2; Diabetes Mellitus, Type 2; Female; Fibrinogen; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Inflammation; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Pyrroles | 2005 |
Coronary risk factors and inflammation in patients with coronary artery disease and internal cardioverter defibrillator implants.
Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; Belgium; Biomarkers; C-Reactive Protein; Coronary Artery Disease; Defibrillators, Implantable; Double-Blind Method; Female; Follow-Up Studies; Glycated Hemoglobin; Greece; Heptanoic Acids; Humans; Inflammation; Inflammation Mediators; Lipids; Male; Middle Aged; Natriuretic Peptide, Brain; Peptide Fragments; Prevalence; Pyrroles; Research Design; Risk Factors; Tachycardia, Ventricular; Treatment Outcome; Ventricular Fibrillation | 2006 |
Short-term effects of low-dose atorvastatin on inflammatory status and lipid profiles in perimenopausal hypercholesterolemic, hypertriglyceridemic women.
Topics: Adult; Atorvastatin; Blood Coagulation; C-Reactive Protein; Cholesterol; Cholesterol, LDL; Female; Fibrinolysis; Gonadal Steroid Hormones; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertriglyceridemia; Inflammation; Lipids; Lipoproteins; Malondialdehyde; Middle Aged; Plasminogen Activator Inhibitor 1; Postmenopause; Premenopause; Prospective Studies; Pyrroles; Time Factors; Tissue Plasminogen Activator; Triglycerides | 2006 |
The effects of atorvastatin (10 mg) on systemic inflammation in heart failure.
Topics: Adult; Aged; Atorvastatin; Biomarkers; C-Reactive Protein; Cross-Over Studies; Double-Blind Method; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Female; Heart Failure; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Middle Aged; Pyrroles; Receptors, Tumor Necrosis Factor, Type I; Treatment Outcome | 2005 |
Effect of low doses of atorvastatin on adiponectin, glucose homeostasis, and clinical inflammatory markers in kidney transplant recipients.
Topics: Adiponectin; Adult; Atorvastatin; Biomarkers; Blood Glucose; C-Reactive Protein; Dyslipidemias; Female; Heptanoic Acids; Homeostasis; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Kidney Transplantation; Lipids; Male; Middle Aged; Prospective Studies; Pyrroles; Tumor Necrosis Factor-alpha | 2005 |
Correlation between inflammation and oxidative stress in normocholesterolemic coronary artery disease patients 'on' and 'off' atorvastatin for short time intervals.
Topics: Atorvastatin; C-Reactive Protein; Cholesterol; Coronary Artery Disease; Drug Administration Schedule; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Middle Aged; Oxidative Stress; Pyrroles; Thiobarbituric Acid Reactive Substances | 2006 |
[Atorvastatin reduces the expression of COX-2 mRNA in peripheral blood monocytes in patients with acute myocardial infarction and modulates the early inflammatory response].
Topics: Aged; Atorvastatin; Cyclooxygenase 2; Female; Heptanoic Acids; Humans; Inflammation; Interleukin-6; Leukocytes, Mononuclear; Male; Middle Aged; Myocardial Infarction; Pyrroles; RNA, Messenger | 2005 |
Effects of obesity on lipid-lowering, anti-inflammatory, and antiatherosclerotic benefits of atorvastatin or pravastatin in patients with coronary artery disease (from the REVERSAL Study).
Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; Biomarkers; Body Mass Index; C-Reactive Protein; Coronary Disease; Coronary Vessels; Disease Progression; Endosonography; Female; Heptanoic Acids; Humans; Inflammation; Lipids; Male; Middle Aged; Obesity; Pravastatin; Pyrroles; Risk Factors | 2006 |
Relation between local temperature and C-reactive protein levels in patients with coronary artery disease: effects of atorvastatin treatment.
Topics: Aged; Atorvastatin; Body Temperature; C-Reactive Protein; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Female; Heptanoic Acids; Humans; Inflammation; Male; Middle Aged; Pyrroles; Thermography | 2007 |
Effects of amlodipine-atorvastatin combination on inflammation markers and insulin sensitivity in normocholesterolemic obese hypertensive patients.
Topics: Adult; Aged; Amlodipine; Atorvastatin; Biomarkers; Blood Glucose; Body Mass Index; Calcium Channel Blockers; Cholesterol; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Inflammation; Insulin Resistance; Interleukin-6; Male; Middle Aged; Obesity; Pyrroles; Tablets; Tumor Necrosis Factor-alpha | 2006 |
Effects of atorvastatin on inflammatory and fibrinolytic parameters in patients with chronic kidney disease.
Topics: Aged; Aged, 80 and over; Atorvastatin; C-Reactive Protein; Cardiovascular Diseases; Chronic Disease; Dose-Response Relationship, Drug; Dyslipidemias; Female; Fibrinogen; Fibrinolysis; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Interleukin-6; Kidney Diseases; Lipid Metabolism; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Prospective Studies; Pyrroles; Tissue Plasminogen Activator | 2006 |
Effects of atorvastatin and aspirin combined therapy on inflammatory responses in patients undergoing coronary artery bypass grafting.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antithrombins; Aspirin; Atorvastatin; Blood Platelets; Cholesterol; Coronary Artery Bypass; Cytokines; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Inflammation; Male; Middle Aged; P-Selectin; Pyrroles; Receptors, Cytokine; Thrombin; Thromboxane B2; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A | 2006 |
The effect of aggressive versus conventional lipid-lowering therapy on markers of inflammatory and oxidative stress.
Topics: Adult; Aged; Antibodies; Atorvastatin; Biomarkers; C-Reactive Protein; Cell Adhesion Molecules; Cholesterol, LDL; Coronary Artery Disease; Double-Blind Method; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Lipoproteins, LDL; Male; Middle Aged; Neopterin; Oxidative Stress; Pyrroles; Simvastatin; von Willebrand Factor | 2007 |
Elevated ICAM-1 and MCP-1 plasma levels in subjects at high cardiovascular risk are diminished by atorvastatin treatment. Atorvastatin on Inflammatory Markers study: a substudy of Achieve Cholesterol Targets Fast with Atorvastatin Stratified Titration.
Topics: Anticholesteremic Agents; Atorvastatin; Cardiovascular Diseases; Chemokine CCL2; Cholesterol; Diabetes Complications; Dose-Response Relationship, Drug; Female; Heptanoic Acids; Humans; Inflammation; Intercellular Adhesion Molecule-1; Male; Metabolic Syndrome; Middle Aged; Prospective Studies; Pyrroles; Treatment Outcome | 2007 |
[Effect of therapy with atorvastatin on parameters of postprandial lipemia and factors of inflammation in patients with ischemic heart disease].
Topics: Adult; Anticholesteremic Agents; Atorvastatin; C-Reactive Protein; Female; Fibrinogen; Heptanoic Acids; Humans; Hyperlipidemias; Inflammation; Lipids; Male; Myocardial Ischemia; Postprandial Period; Pyrroles; Treatment Outcome | 2007 |
Early effects of low versus high dose atorvastatin treatment on coagulation and inflammation parameters in patients with acute coronary syndromes.
Topics: Acute Coronary Syndrome; Atorvastatin; Blood Coagulation; C-Reactive Protein; Dose-Response Relationship, Drug; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Pyrroles | 2008 |
Inflammatory activation during coronary artery surgery and its dose-dependent modulation by statin/ACE-inhibitor combination.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents; Atorvastatin; Coronary Artery Bypass; Coronary Artery Disease; Coronary Circulation; Creatine Kinase; Dose-Response Relationship, Drug; E-Selectin; Enalapril; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Inflammation Mediators; Interleukin-6; Leukocyte Count; Male; Middle Aged; Platelet Count; Pyrroles; Ramipril; Simvastatin; Stroke Volume; Time Factors; Tomography, Emission-Computed, Single-Photon; Treatment Outcome; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1; von Willebrand Factor | 2007 |
Inflammatory breast cancer as a model disease to study tumor angiogenesis: results of a phase IB trial of combination SU5416 and doxorubicin.
Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disease-Free Survival; Doxorubicin; Female; Humans; Indoles; Inflammation; Male; Maximum Tolerated Dose; Middle Aged; Neovascularization, Pathologic; Pyrroles; Treatment Outcome | 2007 |
Inflammation, statin therapy, and risk of stroke after an acute coronary syndrome in the MIRACL study.
Topics: Acute Coronary Syndrome; Aged; Atorvastatin; C-Reactive Protein; Cholesterol, LDL; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Interleukin-6; Male; Middle Aged; Pyrroles; Risk Factors; ROC Curve; Serum Amyloid A Protein; Stroke | 2008 |
Early initiation of low-dose atorvastatin treatment after an acute ST-elevated myocardial infarction, decreases inflammatory process and prevents endothelial injury and activation.
Topics: Atorvastatin; Biomarkers; Electrocardiography; Endothelium, Vascular; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Interleukin-6; Male; Middle Aged; Myocardial Infarction; Plasminogen Activator Inhibitor 1; Pyrroles; Time Factors; Tissue Plasminogen Activator; Vascular Cell Adhesion Molecule-1; von Willebrand Factor | 2009 |
Differential effect of atorvastatin and fenofibrate on plasma oxidized low-density lipoprotein, inflammation markers, and cell adhesion molecules in patients with type 2 diabetes mellitus.
Topics: Atorvastatin; Biomarkers; Cell Adhesion Molecules; Diabetes Mellitus, Type 2; Female; Fenofibrate; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertriglyceridemia; Hypolipidemic Agents; Inflammation; Lipids; Lipoproteins; Lipoproteins, LDL; Male; Middle Aged; Oxidation-Reduction; Pyrroles | 2008 |
[Immunoinflammatory factors in unstable angina. Possibility of influence of atorvastatin].
Topics: Angina, Unstable; Atorvastatin; C-Reactive Protein; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunity, Cellular; Inflammation; Interleukin-4; Male; Middle Aged; Pyrroles; T-Lymphocytes; Treatment Outcome; Tumor Necrosis Factor-alpha | 2007 |
Effects of atorvastatin and pravastatin on glucose tolerance, adipokine levels and inflammatory markers in hypercholesterolaemic patients.
Topics: Adipokines; Aged; Anticholesteremic Agents; Atorvastatin; Biomarkers; Blood Glucose; Cross-Over Studies; Female; Glucose Intolerance; Heptanoic Acids; Humans; Hypercholesterolemia; Inflammation; Male; Middle Aged; Pravastatin; Pyrroles | 2008 |
The effect of darapladib on plasma lipoprotein-associated phospholipase A2 activity and cardiovascular biomarkers in patients with stable coronary heart disease or coronary heart disease risk equivalent: the results of a multicenter, randomized, double-bl
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Aged; Anti-Inflammatory Agents; Anticholesteremic Agents; Atorvastatin; Benzaldehydes; Biomarkers; Coronary Artery Disease; Double-Blind Method; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Interleukins; Male; Middle Aged; Oximes; Prognosis; Pyrroles; Recurrence; Risk Factors | 2008 |
[Comparison of the therapeutic efficacy and tolerability of acemetacin and tolmetin (author's transl)].
Topics: Adult; Aged; Anti-Inflammatory Agents; Double-Blind Method; Female; Humans; In Vitro Techniques; Indoleacetic Acids; Indomethacin; Inflammation; Male; Middle Aged; Pain; Pyrroles; Tolmetin | 1980 |
Similar effects of atorvastatin, simvastatin and pravastatin on thrombogenic and inflammatory parameters in patients with hypercholesterolemia.
Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; C-Reactive Protein; Double-Blind Method; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Inflammation; Lipids; Male; Middle Aged; Pravastatin; Pyrroles; Simvastatin; Therapeutic Equivalency; Thrombophilia; Treatment Outcome | 2001 |
Effects of simvastatin and atorvastatin on inflammation markers in plasma.
Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; Biomarkers; C-Reactive Protein; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-6; Male; Middle Aged; Pyrroles; Simvastatin | 2002 |
[Clopirac in traumatology (author's transl)].
Topics: Anti-Inflammatory Agents; Clinical Trials as Topic; Inflammation; Pyrroles; Wounds and Injuries | 1975 |
240 other study(ies) available for pyrroles and Innate Inflammatory Response
| Article | Year |
|---|---|
Corticotropin-Releasing Factor Aggravates Ischemic Stroke Injury by the Inflammatory Activation of Microglia.
Topics: Animals; Corticotropin-Releasing Hormone; Disease Models, Animal; Inflammation; Ischemic Stroke; Male; Mice; Microglia; Neurons; NF-kappa B; Peptide Fragments; Peptides, Cyclic; Phosphorylation; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone | 2022 |
3D-Printed Polypyrrole Microneedle Arrays for Electronically Controlled Transdural Drug Release.
Topics: Drug Liberation; Humans; Inflammation; Polymers; Printing, Three-Dimensional; Pyrroles | 2022 |
Histatin-1 loaded multifunctional, adhesive and conductive biomolecular hydrogel to treat diabetic wound.
Topics: Adhesives; Diabetes Mellitus; Gelatin; Histatins; Humans; Hydrogels; Inflammation; Polymers; Pyrroles; Wound Healing | 2022 |
SARS-CoV-2 Causes Lung Inflammation through Metabolic Reprogramming and RAGE.
Topics: COVID-19; Humans; Inflammation; Pneumonia; Pyridazines; Pyrroles; SARS-CoV-2 | 2022 |
Antidiabetic Effect of
Topics: Adipocytes; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Down-Regulation; Gene Expression; Glucose; Hypoglycemic Agents; Inflammation; Lipoproteins, LDL; Momordica charantia; Phenylpropionates; Plant Extracts; Pyrroles; Tamarindus | 2022 |
Esaxerenone Blocks Vascular Endothelial Inflammation Through SGK1.
Topics: Anti-Inflammatory Agents; Cytokines; Endothelial Cells; Glucocorticoids; Humans; Inflammation; NF-kappa B; Pyrroles; Receptors, Mineralocorticoid; RNA, Messenger; Spironolactone; Sulfones; Tumor Necrosis Factor-alpha | 2022 |
Early posttraumatic CSF1R inhibition via PLX3397 leads to time- and sex-dependent effects on inflammation and neuronal maintenance after traumatic brain injury in mice.
Topics: Aminopyridines; Animals; Brain Injuries, Traumatic; Disease Models, Animal; Female; Inflammation; Macrophage Colony-Stimulating Factor; Male; Mice; Mice, Inbred C57BL; Microglia; Oxidoreductases; Pyrroles; Receptors, Colony-Stimulating Factor; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor | 2022 |
Tofacitinib treatment modulates the levels of several inflammation-related plasma proteins in rheumatoid arthritis and baseline levels of soluble biomarkers associate with the treatment response.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Biomarkers; Blood Proteins; Chemokines; Humans; Inflammation; Interleukin-6; Protein Kinase Inhibitors; Pyrroles; Treatment Outcome | 2022 |
Synthesis, biological evaluation and molecular modeling of novel selective COX-2 inhibitors: sulfide, sulfoxide, and sulfone derivatives of 1,5-diarylpyrrol-3-substituted scaffold.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Design; Humans; Inflammation; Male; Mice; Molecular Docking Simulation; Molecular Structure; Protein Binding; Pyrroles; Rats, Sprague-Dawley; Rats, Wistar; Structure-Activity Relationship; Sulfides; Sulfones; Sulfoxides | 2019 |
(10
Topics: Animals; Aquatic Organisms; Azepines; Caco-2 Cells; Coculture Techniques; Colitis, Ulcerative; Crohn Disease; Dinoprostone; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Intestines; Porifera; Pyrroles; THP-1 Cells | 2019 |
Modulation of smoke-induced DNA and microRNA alterations in mouse lung by licofelone, a triple COX-1, COX-2 and 5-LOX inhibitor.
Topics: Animals; Anticarcinogenic Agents; Arachidonate 5-Lipoxygenase; Carcinogenesis; Cyclooxygenase 1; Cyclooxygenase 2; Disease Models, Animal; DNA Adducts; DNA Damage; Drug Administration Schedule; Female; Humans; Inflammation; Lung; Lung Neoplasms; Male; Membrane Proteins; Mice; MicroRNAs; Pyrroles; Time Factors; Tobacco Smoke Pollution; Toxicity Tests, Subchronic | 2020 |
Vonoprazan-associated Gastric Mucosal Redness: A Report of Four Cases.
Topics: Aged; Aged, 80 and over; Endoscopy, Digestive System; Female; Gastric Mucosa; Gastroesophageal Reflux; Humans; Inflammation; Male; Proton Pump Inhibitors; Pyrroles; Sulfonamides; Treatment Outcome | 2020 |
Dexamethasone and Tofacitinib suppress NADPH oxidase expression and alleviate very-early-onset ileocolitis in mice deficient in GSH peroxidase 1 and 2.
Topics: Animals; Apoptosis; Crohn Disease; Dexamethasone; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Ileum; Inflammation; Inflammatory Bowel Diseases; Mice; Mice, Inbred C57BL; NADPH Oxidase 1; NADPH Oxidases; Oxidation-Reduction; Peroxidases; Piperidines; Pyrimidines; Pyrroles | 2019 |
Ethyl benzoate bearing pyrrolizine/indolizine moieties: Design, synthesis and biological evaluation of anti-inflammatory and cytotoxic activities.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Benzoates; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Edema; Humans; Indolizines; Inflammation; Molecular Structure; Pain; Pyrroles; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2020 |
Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4
Topics: Animals; Autoimmunity; Carrier Proteins; Cells, Cultured; Enzyme Activators; Female; Humans; Inflammation; Membrane Proteins; Mice; Mice, Inbred C57BL; Pyridazines; Pyrroles; Th1 Cells; Thyroid Hormone-Binding Proteins; Thyroid Hormones | 2020 |
An Injectable Conductive Three-Dimensional Elastic Network by Tangled Surgical-Suture Spring for Heart Repair.
Topics: Animals; Cell Adhesion; Cell Differentiation; Cell Survival; Dihydroxyphenylalanine; Disease Models, Animal; Elasticity; Electric Conductivity; Electrochemistry; Heart Function Tests; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Injections; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Neovascularization, Physiologic; Polyglutamic Acid; Polymers; Pyrroles; Rats, Sprague-Dawley; Sutures; Wound Healing | 2019 |
Microglial depletion prevents extracellular matrix changes and striatal volume reduction in a model of Huntington's disease.
Topics: Aminopyridines; Animals; Astrocytes; Chondroitin Sulfate Proteoglycans; Cytokines; Disease Models, Animal; Down-Regulation; Extracellular Matrix; Hand Strength; Humans; Huntingtin Protein; Huntington Disease; Inflammation; Mice; Mice, Transgenic; Microglia; Neostriatum; Neurites; Pyrroles; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Recognition, Psychology; RNA, Messenger; Synapses; Transcriptome | 2020 |
CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer.
Topics: Animals; Antineoplastic Agents; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Chemokine CXCL9; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; DNA Damage; Female; Genomic Instability; Humans; Immune System; Inflammation; Interferon-gamma; Lung Neoplasms; Male; Mice; Micronucleus Tests; Programmed Cell Death 1 Receptor; Pyrazoles; Pyrroles; Signal Transduction; Small Cell Lung Carcinoma; Tumor Necrosis Factor-alpha | 2020 |
Microglial depletion and repopulation in brain slice culture normalizes sensitized proinflammatory signaling.
Topics: Aminopyridines; Animals; Ethanol; Hippocampus; Inflammation; Microglia; Neural Stem Cells; Organ Culture Techniques; Pyrroles; Rats; Signal Transduction; Toll-Like Receptors | 2020 |
Synthetic 4-Hydroxy Auxarconjugatin B, a Novel Autophagy Inducer, Attenuates Gouty Inflammation by Inhibiting the NLRP3 Inflammasome.
Topics: Animals; Arthritis, Gouty; Autophagy; CARD Signaling Adaptor Proteins; Cell Line; Disease Models, Animal; Humans; Inflammasomes; Inflammation; Lipopolysaccharides; Lysosomes; Macrophages; Male; Mice, Inbred C57BL; Mitochondria; Models, Biological; NLR Family, Pyrin Domain-Containing 3 Protein; Organelle Biogenesis; Protein Multimerization; Pyrroles; Sirtuin 1 | 2020 |
Isolation of Unstable Isomers of Lucilactaene and Evaluation of Anti-Inflammatory Activity of Secondary Metabolites Produced by the Endophytic Fungus
Topics: Animals; Anti-Inflammatory Agents; Endophytes; Furans; Fusarium; Inflammation; Lipopolysaccharides; Mice; Plant Roots; Pyrroles; RAW 264.7 Cells; Scutellaria baicalensis; Secondary Metabolism | 2020 |
Age-related changes to macrophages are detrimental to fracture healing in mice.
Topics: Age Factors; Aminopyridines; Animals; Bony Callus; Cellular Senescence; Fracture Healing; Fractures, Bone; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; Models, Animal; Pyrroles; RNA-Seq; Tibia; Transcriptome | 2020 |
Saroglitazar attenuates renal fibrosis induced by unilateral ureteral obstruction via inhibiting TGF-β/Smad signaling pathway.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Fibrosis; Inflammation; Kidney Diseases; Male; Oxidative Stress; Phenylpropionates; PPAR alpha; PPAR gamma; Pyrroles; Rats; Rats, Sprague-Dawley; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta1; Ureteral Obstruction | 2020 |
Lipid Profiles in Patients With Ulcerative Colitis Receiving Tofacitinib-Implications for Cardiovascular Risk and Patient Management.
Topics: Arthritis, Rheumatoid; Cardiovascular Diseases; Cholesterol; Clinical Trials, Phase III as Topic; Colitis, Ulcerative; Heart Disease Risk Factors; Humans; Inflammation; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Piperidines; Protein Kinase Inhibitors; Psoriasis; Pyrimidines; Pyrroles; Risk Factors; Treatment Outcome | 2021 |
FOXM1 activates JAK1/STAT3 pathway in human osteoarthritis cartilage cell inflammatory reaction.
Topics: Cartilage, Articular; Cells, Cultured; Chondrocytes; Forkhead Box Protein M1; Gene Silencing; Humans; Inflammation; Janus Kinase 1; Lipopolysaccharides; Osteoarthritis; Phosphorylation; Protein Binding; Pyridines; Pyrroles; Signal Transduction; STAT3 Transcription Factor; Triazines; Tyrphostins | 2021 |
Cardioprotective Effects of a Nonsteroidal Mineralocorticoid Receptor Blocker, Esaxerenone, in Dahl Salt-Sensitive Hypertensive Rats.
Topics: Animals; Cardiotonic Agents; Electrocardiography; Fibrosis; Hypertension; Inflammation; Male; Mineralocorticoid Receptor Antagonists; Pyrroles; Rats, Inbred Dahl; Receptors, Mineralocorticoid; Sodium Chloride, Dietary; Sulfones; Survival Analysis; Ventricular Remodeling | 2021 |
Pharmacologic modulation of RNA splicing enhances anti-tumor immunity.
Topics: Animals; Antigen Presentation; Antigens, Neoplasm; Cell Line, Tumor; Cell Proliferation; Epitopes; Ethylenediamines; Gene Expression Regulation, Neoplastic; Hematopoiesis; Histocompatibility Antigens Class I; Humans; Immune Checkpoint Inhibitors; Immunotherapy; Inflammation; Mice, Inbred C57BL; Neoplasms; Peptides; Protein Isoforms; Pyrroles; RNA Splicing; Sulfonamides; T-Lymphocytes | 2021 |
Preseptal cellulitis, intraocular inflammatory reaction and corneal persistent epithelial defect as side effects of avapritinib.
Topics: Aged; Antineoplastic Agents; Cellulitis; Epithelium, Corneal; Eye Diseases; Female; Gastrointestinal Stromal Tumors; Humans; Inflammation; Neoplasm Metastasis; Neoplasm Staging; Pyrazoles; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Triazines | 2021 |
Qing-Fei-Pai-Du decoction and wogonoside exert anti-inflammatory action through down-regulating USP14 to promote the degradation of activating transcription factor 2.
Topics: Activating Transcription Factor 2; Animals; Cell Line; Colitis; Cullin Proteins; Cytokines; Dextran Sulfate; Down-Regulation; Drugs, Chinese Herbal; Flavanones; Glucosides; Inflammation; Macrophages; Male; Mice; Mice, Inbred C57BL; Phosphorylation; Proteasome Endopeptidase Complex; Proteolysis; Pyrroles; Pyrrolidines; Ubiquitin Thiolesterase; Ubiquitination | 2021 |
A novel JAK inhibitor JTE-052 reduces skin inflammation and ameliorates chronic dermatitis in rodent models: Comparison with conventional therapeutic agents.
Topics: Animals; Cyclosporine; Cytokines; Dermatitis, Atopic; Female; Haptens; Humans; Immunoglobulin E; Inflammation; Interleukin-23; Interleukin-23 Subunit p19; Janus Kinase Inhibitors; Male; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pyrroles; Rats; Rats, Inbred BN; Skin; Thymic Stromal Lymphopoietin | 2018 |
Discovery of potent and efficacious pyrrolopyridazines as dual JAK1/3 inhibitors.
Topics: Animals; Binding Sites; Catalytic Domain; Cell Line; Crystallography, X-Ray; Disease Models, Animal; Drug Evaluation, Preclinical; Half-Life; Humans; Inflammation; Inhibitory Concentration 50; Janus Kinase 1; Janus Kinase 2; Janus Kinase 3; Mice; Mice, Inbred BALB C; Molecular Conformation; Molecular Dynamics Simulation; Protein Kinase Inhibitors; Pyridazines; Pyrroles; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; TYK2 Kinase | 2017 |
Tofacitinib restores the inhibition of reverse cholesterol transport induced by inflammation: understanding the lipid paradox associated with rheumatoid arthritis.
Topics: Animals; Arthritis, Rheumatoid; Cholesterol; Diet, High-Fat; Dose-Response Relationship, Drug; Inflammation; Lipids; Macrophages; Male; Piperidines; Pyrimidines; Pyrroles; Rabbits; Structure-Activity Relationship | 2017 |
Novel drug delivery of dual acting prodrugs of hydroxychloroquine with aryl acetic acid NSAIDs: Design, kinetics and pharmacological study.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Arthritis, Rheumatoid; Carrageenan; Diclofenac; Drug Design; Female; Freund's Adjuvant; Hydroxychloroquine; Inflammation; Male; Mice; Prodrugs; Pyrroles; Rats; Rats, Wistar | 2017 |
JAK/STAT-1 Signaling Is Required for Reserve Intestinal Stem Cell Activation during Intestinal Regeneration Following Acute Inflammation.
Topics: Acute Disease; Animals; Apoptosis; Cytokines; Enteritis; Inflammation; Intestinal Mucosa; Intestine, Small; Janus Kinases; Mice; Mice, Transgenic; Piperidines; Pyrimidines; Pyrroles; Regeneration; Signal Transduction; STAT1 Transcription Factor; Stem Cells | 2018 |
Saroglitazar reduces obesity and associated inflammatory consequences in murine adipose tissue.
Topics: Adipose Tissue; Animals; Energy Metabolism; Glucose; Homeostasis; Hypertrophy; Inflammation; Male; Mice; Mice, Inbred C57BL; Obesity; Organ Specificity; Phenylpropionates; Pyrroles | 2018 |
Topical Sunitinib ointment alleviates Psoriasis-like inflammation by inhibiting the proliferation and apoptosis of keratinocytes.
Topics: Administration, Topical; Animals; Apoptosis; Cell Line; Cell Proliferation; Down-Regulation; Gene Expression Regulation; Indoles; Inflammation; Keratinocytes; Male; Mice; Organ Size; Phosphoproteins; Psoriasis; Pyrroles; Signal Transduction; STAT3 Transcription Factor; Sunitinib; Vascular Endothelial Growth Factor A | 2018 |
Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy.
Topics: Aminopyridines; Amyotrophic Lateral Sclerosis; Animals; Gene Expression Profiling; Gliosis; Humans; Inflammation; Mice; Mice, Transgenic; Motor Neurons; Muscle, Skeletal; Mutation; Myeloid Cells; Pyrroles; Recovery of Function; Spinal Cord; Superoxide Dismutase-1; TDP-43 Proteinopathies | 2018 |
Synthesis and evaluation of 1H-pyrrole-2,5-dione derivatives as cholesterol absorption inhibitors for suppressing the formation of foam cells and inflammatory response.
Topics: Animals; Anticholesteremic Agents; Cell Proliferation; Cholesterol; Dose-Response Relationship, Drug; Foam Cells; HEK293 Cells; Humans; Inflammation; Lipids; Macrophages; Mice; Molecular Structure; Pyrroles; RAW 264.7 Cells; Structure-Activity Relationship | 2018 |
The anti-inflammatory effect of topical tofacitinib on immediate and late-phase cutaneous allergic reactions in dogs: a placebo-controlled pilot study.
Topics: Animals; Anti-Inflammatory Agents; Dermatitis, Atopic; Dog Diseases; Dogs; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Inflammation; Pilot Projects; Piperidines; Pyrimidines; Pyrroles | 2018 |
Specific Inhibitor of Smad3 (SIS3) Attenuates Fibrosis, Apoptosis, and Inflammation in Unilateral Ureteral Obstruction Kidneys by Inhibition of Transforming Growth Factor β (TGF-β)/Smad3 Signaling.
Topics: Animals; Apoptosis; Fibrosis; Inflammation; Isoquinolines; Kidney; Male; Mice, Inbred BALB C; Myofibroblasts; Pyridines; Pyrroles; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta; Ureteral Obstruction | 2018 |
Discriminating phenotypic signatures identified for tocilizumab, adalimumab, and tofacitinib monotherapy and their combinations with methotrexate.
Topics: Adalimumab; Antibodies, Monoclonal, Humanized; Arthritis, Rheumatoid; Drug Therapy, Combination; Humans; Inflammation; Methotrexate; Phenotype; Piperidines; Pyrimidines; Pyrroles; Receptors, Interleukin-6; Signal Transduction | 2018 |
SIS3, a specific inhibitor of smad3, attenuates bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Bleomycin; Collagen Type I; Inflammation; Isoquinolines; Lung; Male; Mice; Mice, Inbred C57BL; Phosphorylation; Pulmonary Fibrosis; Pyridines; Pyrroles; Smad3 Protein | 2018 |
Identification of a Novel Inhibitor of Human Rhinovirus Replication and Inflammation in Airway Epithelial Cells.
Topics: Aldehyde Oxidoreductases; Benzamides; Bronchi; Cells, Cultured; Enzyme Inhibitors; Epithelial Cells; Humans; Inflammation; Nitric Oxide Synthase Type II; Picornaviridae Infections; Pyrroles; Rhinovirus; Virus Replication | 2019 |
Synthesis and Evaluation of 2-Azetidinone and 1H-Pyrrole-2,5-dione Derivatives as Cholesterol Absorption Inhibitors for Reducing Inflammation Response and Oxidative Stress.
Topics: Anticholesteremic Agents; Azetidines; Biological Transport; Cholesterol; HEK293 Cells; Humans; Inflammation; Oxidative Stress; Pyrroles; Structure-Activity Relationship | 2019 |
In Vivo Evaluation of Anti-inflammatory Activity of 2-[3-Acetyl- 5-(4-chloro-phenyl)-2-methyl-pyrrol-1-yl]-4-methylsulfanylbutyric Acid.
Topics: Animals; Anti-Inflammatory Agents; Butyrates; Carrageenan; Diclofenac; Edema; Foot; Hindlimb; Inflammation; Pyrroles; Rats | 2018 |
Suppression of hematopoietic cell kinase ameliorates the bone destruction associated with inflammation.
Topics: Animals; Blotting, Western; Bone Resorption; Cell Differentiation; Cells, Cultured; Gene Expression Regulation; Inflammation; Mice; Mice, Inbred BALB C; Osteoclasts; Osteogenesis; Proto-Oncogene Proteins c-hck; Pyrimidines; Pyrroles; RNA; src-Family Kinases | 2020 |
Targeting microglia attenuates neuroinflammation-related neural damage in mice carrying human PLP1 mutations.
Topics: Aminopyridines; Animals; Anti-Inflammatory Agents; Central Nervous System Diseases; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Inflammation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Microscopy, Electron, Transmission; Mutation; Myelin Proteolipid Protein; Neurons; Pyrroles; T-Lymphocytes; Tomography, Optical Coherence | 2019 |
Macrophage-Derived Legumain Promotes Pulmonary Hypertension by Activating the MMP (Matrix Metalloproteinase)-2/TGF (Transforming Growth Factor)-β1 Signaling.
Topics: Animals; Caspase Inhibitors; Cysteine Endopeptidases; Extracellular Matrix Proteins; Female; Follow-Up Studies; Humans; Hypertension, Pulmonary; Hypoxia; Indoles; Inflammation; Lung; Macrophages; Male; Matrix Metalloproteinase 2; Mice; Middle Aged; Monocrotaline; Pyrroles; Rats; Severity of Illness Index; Signal Transduction; Transforming Growth Factor beta1; Vascular Remodeling | 2019 |
A Macromolecular Janus Kinase (JAK) Inhibitor Prodrug Effectively Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice.
Topics: Animals; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Inflammation; Janus Kinases; Male; Methacrylates; Mice; Piperidines; Polymers; Prodrugs; Pyrimidines; Pyrroles | 2019 |
Mitochondria-Targeted Ratiometric Fluorescent Probe Based on Diketopyrrolopyrrole for Detecting and Imaging of Endogenous Superoxide Anion in Vitro and in Vivo.
Topics: Animals; Cell Proliferation; Fluorescent Dyes; Humans; In Vitro Techniques; Inflammation; Ketones; Lipopolysaccharides; MCF-7 Cells; Mice; Mitochondria; Optical Imaging; Pyrroles; Superoxides | 2019 |
Elevated circulating TGFβ1 during acute liver failure activates TGFβR2 on cortical neurons and exacerbates neuroinflammation and hepatic encephalopathy in mice.
Topics: Animals; Antibodies; Azoxymethane; Benzamides; Carcinogens; Cell Line, Transformed; Cerebral Cortex; Disease Models, Animal; Hepatic Encephalopathy; Inflammation; Isoquinolines; Liver; Liver Failure, Acute; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Neurons; Phagocytosis; Pyrazoles; Pyridines; Pyrroles; Receptor, Transforming Growth Factor-beta Type II; Signal Transduction; Transforming Growth Factor beta1; Up-Regulation | 2019 |
TRPV4-induced inflammatory response is involved in neuronal death in pilocarpine model of temporal lobe epilepsy in mice.
Topics: Animals; Astrocytes; Epilepsy, Temporal Lobe; Inflammasomes; Inflammation; Leucine; Male; Mice; Mice, Inbred ICR; Microglia; Morpholines; Neurons; Pilocarpine; Pyrroles; Status Epilepticus; Sulfonamides; TRPV Cation Channels | 2019 |
Chronic inflammation, cognitive impairment, and distal brain region alteration following intracerebral hemorrhage.
Topics: Aminopyridines; Animals; Brain; Cerebral Hemorrhage; Cognition; Cognitive Dysfunction; Disease Models, Animal; Fingolimod Hydrochloride; Flow Cytometry; Hippocampus; Inflammation; Male; Mice; Mice, Inbred C57BL; Microglia; Neuroimaging; Neuronal Plasticity; Pyrroles; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor | 2019 |
IRF1 is critical for the TNF-driven interferon response in rheumatoid fibroblast-like synoviocytes : JAKinibs suppress the interferon response in RA-FLSs.
Topics: Animals; Arthritis, Rheumatoid; Azetidines; Biomarkers; Female; Gene Expression; Humans; Inflammation; Interferon Regulatory Factor-1; Interferons; Janus Kinase Inhibitors; Mice; Mice, Inbred C57BL; Mice, Transgenic; Piperidines; Purines; Pyrazoles; Pyrimidines; Pyrroles; Signal Transduction; Sulfonamides; Synovial Membrane; Synoviocytes; Tumor Necrosis Factor-alpha | 2019 |
Design and pharmacology of a highly specific dual FMS and KIT kinase inhibitor.
Topics: Aminopyridines; Animals; Cell Survival; Chromatography, Affinity; Crystallization; Escherichia coli; Human Umbilical Vein Endothelial Cells; Humans; Indoles; Inflammation; Macrophages; Mast Cells; Models, Molecular; Molecular Structure; Mutation, Missense; Neoplasm Metastasis; Oncogene Protein gp140(v-fms); Osteoclasts; Protein Conformation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrroles; Sf9 Cells; Spodoptera | 2013 |
Promising role of ferulic acid, atorvastatin and their combination in ameliorating high fat diet-induced stress in mice.
Topics: Animals; Antioxidants; Atorvastatin; Coumaric Acids; Diet, High-Fat; Drug Therapy, Combination; Free Radical Scavengers; Hepatocytes; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Inflammation; Interleukin-6; Lipid Peroxidation; Liver; Male; Mice; NF-kappa B; Oxidative Stress; Pyrroles; Reactive Oxygen Species; Signal Transduction; Tumor Necrosis Factor-alpha; Weight Gain | 2013 |
Monitoring plaque inflammation in atherosclerotic rabbits with an iron oxide (P904) and (18)F-FDG using a combined PET/MR scanner.
Topics: Animals; Aorta, Abdominal; Aortic Diseases; Atherosclerosis; Atorvastatin; Contrast Media; Dextrans; Disease Models, Animal; Disease Progression; Fluorodeoxyglucose F18; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Magnetic Resonance Imaging; Magnetite Nanoparticles; Plaque, Atherosclerotic; Positron-Emission Tomography; Predictive Value of Tests; Pyrroles; Rabbits; Radiography; Radiopharmaceuticals; Time Factors | 2013 |
[Role of inflammation in etiology of atrial fibrillation--is lone arrhythmia really alone].
Topics: Atorvastatin; Atrial Fibrillation; C-Reactive Protein; Fibrinogen; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Middle Aged; Pyrroles; Recurrence | 2012 |
In vivo evaluation of atherosclerotic plaque inflammation and of anti-inflammatory effects of statins by 18F-fluorodeoxyglucose positron emission tomography.
Topics: Aorta, Thoracic; Atherosclerosis; Atorvastatin; Carotid Arteries; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Plaque, Atherosclerotic; Pyrroles; Radionuclide Imaging | 2013 |
Atorvastatin enhance efficacy of mesenchymal stem cells treatment for swine myocardial infarction via activation of nitric oxide synthase.
Topics: Animals; Apoptosis; Atorvastatin; C-Reactive Protein; Disease Models, Animal; Enzyme Activation; Fibrosis; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Mesenchymal Stem Cell Transplantation; Myocardial Infarction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Pyrroles; Swine; Tomography, Emission-Computed, Single-Photon; Ventricular Function, Left | 2013 |
Redox markers and inflammation are differentially affected by atorvastatin, pravastatin or simvastatin administered before endotoxin-induced acute lung injury.
Topics: Animals; Atorvastatin; Biomarkers; Endotoxins; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Lung Injury; Male; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Pravastatin; Pyrroles; Simvastatin | 2013 |
The new small-molecule mixed-lineage kinase 3 inhibitor URMC-099 is neuroprotective and anti-inflammatory in models of human immunodeficiency virus-associated neurocognitive disorders.
Topics: Animals; Bone Marrow Transplantation; Cell Line, Transformed; Cells, Cultured; CX3C Chemokine Receptor 1; Cytokines; Disease Models, Animal; Embryo, Mammalian; Gene Products, tat; Green Fluorescent Proteins; Hippocampus; HIV Infections; HIV-1; Humans; Inflammation; MAP Kinase Kinase Kinases; Mice; Mice, Transgenic; Microscopy, Immunoelectron; Mitogen-Activated Protein Kinase Kinase Kinase 11; Neuroprotective Agents; Phagocytosis; Phosphorylation; Pyridines; Pyrroles; Rats; Receptors, Chemokine; Signal Transduction; Statistics, Nonparametric; tat Gene Products, Human Immunodeficiency Virus; Time Factors; Transfection | 2013 |
Atorvastatin favorably modulates proinflammatory cytokine profile in patients following deep vein thrombosis.
Topics: Atorvastatin; C-Reactive Protein; Cytokines; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Interleukins; P-Selectin; Pyrroles; Venous Thromboembolism | 2013 |
Improved neurocognitive functions correlate with reduced inflammatory burden in atrial fibrillation patients treated with intensive cholesterol lowering therapy.
Topics: Aged; Amygdala; Anticholesteremic Agents; Atorvastatin; Atrial Fibrillation; Azetidines; Brain; Cognition; Electrocardiography; Executive Function; Ezetimibe; Female; Heptanoic Acids; Hippocampus; Humans; Image Processing, Computer-Assisted; Inflammation; Magnetic Resonance Imaging; Male; Memory; Neuroimaging; Neuropsychological Tests; Psychomotor Performance; Pyrroles; Reaction Time; Vocabulary | 2013 |
Inhibition of VEGFR-2 reverses type 1 diabetes in NOD mice by abrogating insulitis and restoring islet function.
Topics: Animals; Diabetes Mellitus, Type 1; Female; Humans; Hyperglycemia; Indoles; Inflammation; Islets of Langerhans; Mice; Mice, Inbred NOD; Pancreas; Protein Kinase Inhibitors; Pyrroles; Sunitinib; Vascular Endothelial Growth Factor Receptor-2 | 2013 |
Atorvastatin safety in Kawasaki disease patients with coronary artery aneurysms.
Topics: Administration, Oral; Anthropometry; Anti-Inflammatory Agents; Atorvastatin; Canada; Child; Child Development; Cholesterol; Coronary Aneurysm; Coronary Vessels; Dose-Response Relationship, Drug; Drug Monitoring; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Liver Function Tests; Male; Medical Records, Problem-Oriented; Mucocutaneous Lymph Node Syndrome; Pyrroles; Retrospective Studies | 2014 |
Combination therapy with atorvastatin and amlodipine suppresses angiotensin II-induced aortic aneurysm formation.
Topics: Amlodipine; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apoptosis; Atorvastatin; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Drug Therapy, Combination; Enzyme Activation; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Lipids; Male; Matrix Metalloproteinases; Mice; Mice, Knockout; Pyrroles; rho-Associated Kinases | 2013 |
Improvement of the efficacy of dihydroartemisinin with atorvastatin in an experimental cerebral malaria murine model.
Topics: Animals; Anti-Inflammatory Agents; Antimalarials; Artemisinins; Atorvastatin; Biomarkers; Disease Models, Animal; Drug Therapy, Combination; Female; Heptanoic Acids; Inflammation; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Pyrroles; Survival Analysis; Treatment Outcome | 2013 |
Comment on atorvastatin safety in kawasaki disease patients with coronary artery aneurysms.
Topics: Atorvastatin; Child Development; Coronary Aneurysm; Coronary Vessels; Female; Heptanoic Acids; Humans; Inflammation; Male; Mucocutaneous Lymph Node Syndrome; Pyrroles | 2014 |
Author reply to comment on "atorvastatin safety in Kawasaki disease patients with coronary artery aneurysms".
Topics: Atorvastatin; Child Development; Coronary Aneurysm; Coronary Vessels; Female; Heptanoic Acids; Humans; Inflammation; Male; Mucocutaneous Lymph Node Syndrome; Pyrroles | 2014 |
Are statins 'IDEAL' for non-alcoholic fatty liver disease?
Topics: Atorvastatin; Carcinoma, Hepatocellular; Cardiovascular Diseases; Dyslipidemias; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Liver; Liver Neoplasms; Male; Metabolic Syndrome; Non-alcoholic Fatty Liver Disease; Obesity; Pyrroles; Triglycerides | 2014 |
Atorvastatin decreases bone loss, inflammation and oxidative stress in experimental periodontitis.
Topics: Alveolar Bone Loss; Animals; Atorvastatin; Heptanoic Acids; Inflammation; Male; Oxidative Stress; Periodontitis; Pyrroles; Rats; Rats, Wistar | 2013 |
Inflammatory stress induces statin resistance by disrupting 3-hydroxy-3-methylglutaryl-CoA reductase feedback regulation.
Topics: Animals; Apolipoproteins E; Atorvastatin; CD36 Antigens; Cholesterol; Cholesterol, Dietary; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance; Feedback, Physiological; Hep G2 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Inflammation; Inflammation Mediators; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pyrroles; RNA Interference; Scavenger Receptors, Class A; Stress, Physiological; Time Factors; Transfection | 2014 |
10-Dehydrogingerdione raises HDL-cholesterol through a CETP inhibition and wards off oxidation and inflammation in dyslipidemic rabbits.
Topics: Animals; Atorvastatin; C-Reactive Protein; Cell Proliferation; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Diet, Atherogenic; Disease Models, Animal; Dyslipidemias; Guaiacol; Heptanoic Acids; Inflammation; Male; Mass Spectrometry; Oxygen; Pyrroles; Rabbits; Risk Factors | 2013 |
α7 Nicotinic receptor agonist enhances cognition in aged 3xTg-AD mice with robust plaques and tangles.
Topics: Aging; alpha7 Nicotinic Acetylcholine Receptor; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cognition; Humans; Inflammation; Male; Memory; Mice; Mice, Transgenic; Neurofibrillary Tangles; Nootropic Agents; Phosphorylation; Plaque, Amyloid; Pyridazines; Pyrroles; tau Proteins | 2014 |
Pharmacologic inhibition of S-nitrosoglutathione reductase protects against experimental asthma in BALB/c mice through attenuation of both bronchoconstriction and inflammation.
Topics: Aldehyde Oxidoreductases; Animals; Asthma; Benzamides; Bronchoconstriction; Female; Inflammation; Mice; Mice, Inbred BALB C; Pyrroles | 2014 |
Inhibition of vascular endothelial growth factor receptor under hypoxia causes severe, human-like pulmonary arterial hypertension in mice: potential roles of interleukin-6 and endothelin.
Topics: Animals; Biomarkers; Body Weight; Cell Hypoxia; Cell Line; Disease Models, Animal; Endothelial Cells; Endothelin-1; Heart Rate; Humans; Hypertension, Pulmonary; Indoles; Inflammation; Interleukin-6; Lung; Male; Mice; Pulmonary Artery; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Signal Transduction; Up-Regulation | 2014 |
Potential involvement of μ-opioid receptor dysregulation on the reduced antinociception of morphine in the inflammatory pain state in mice.
Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Freund's Adjuvant; Ganglia, Spinal; Hyperalgesia; Indoles; Inflammation; Injections, Subcutaneous; Male; Mice; Mice, Inbred Strains; Morphine; Pain; Phosphorylation; Protein Kinase C-alpha; Pyrroles; Receptors, Opioid, mu; Spinal Cord | 2014 |
Effects of single-dose atorvastatin on interleukin-6, interferon gamma, and myocardial no-reflow in a rabbit model of acute myocardial infarction and reperfusion.
Topics: Animals; Anticholesteremic Agents; Atorvastatin; Coronary Occlusion; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Heptanoic Acids; Immunohistochemistry; Inflammation; Interferon-gamma; Interleukin-6; Ligation; Male; Multivariate Analysis; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Necrosis; No-Reflow Phenomenon; Pyrroles; Rabbits; Random Allocation | 2014 |
[A new therapeutical option for chronic inflammation in rheumatology: janus kinases inhibitors (JAK)].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Chronic Disease; Drug Approval; Humans; Inflammation; Janus Kinases; Piperidines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Rheumatic Diseases; Switzerland | 2014 |
Nuclear factor κB inhibition reduces lung vascular lumen obliteration in severe pulmonary hypertension in rats.
Topics: Animals; Apoptosis; CD4-Positive T-Lymphocytes; Familial Primary Pulmonary Hypertension; Humans; Hypertension, Pulmonary; Hypoxia; Indoles; Inflammation; Interleukin-6; Leukocyte Common Antigens; Lung; NF-kappa B; Pulmonary Artery; Pyrroles; Pyrrolidines; Rats; Signal Transduction; Thiocarbamates; Time Factors | 2014 |
Effects of atorvastatin on the inflammation regulation and elimination of subdural hematoma in rats.
Topics: Analysis of Variance; Animals; Atorvastatin; Blood Cell Count; Brain; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hematoma, Subdural; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Image Processing, Computer-Assisted; Inflammation; Lipids; Magnetic Resonance Imaging; Male; Neurologic Examination; Pyrroles; Rats; Rats, Wistar; Time Factors | 2014 |
Statin-induced impairment of monocyte migration is gender-related.
Topics: Atherosclerosis; Atorvastatin; Cell Movement; Female; Healthy Volunteers; Heptanoic Acids; Humans; Inflammation; Lipopolysaccharides; Male; Monocytes; Pyrroles; Sex Characteristics; Simvastatin; Tumor Necrosis Factor-alpha | 2014 |
Is it not timely to consider how to balance cardiorenometabolic benefits and risks of statins?
Topics: Aorta, Thoracic; Atherosclerosis; Carotid Arteries; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Plaque, Atherosclerotic; Pyrroles; Radionuclide Imaging | 2014 |
Reply: is it not timely to consider how to balance cardiorenometabolic benefits and risks of statins?
Topics: Aorta, Thoracic; Atherosclerosis; Carotid Arteries; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Plaque, Atherosclerotic; Pyrroles; Radionuclide Imaging | 2014 |
Effects of single pill-based combination therapy of amlodipine and atorvastatin on within-visit blood pressure variability and parameters of renal and vascular function in hypertensive patients with chronic kidney disease.
Topics: Aged; Amlodipine; Antihypertensive Agents; Atorvastatin; Biomarkers; Blood Pressure; Capsules; Drug Therapy, Combination; Female; Glucose; Heptanoic Acids; Humans; Hypertension; Inflammation; Kidney; Kidney Function Tests; Lipid Metabolism; Male; Multivariate Analysis; Oxidative Stress; Pyrroles; Regression Analysis; Renal Insufficiency, Chronic | 2014 |
Atorvastatin improves survival of implanted stem cells in a rat model of renal ischemia-reperfusion injury.
Topics: Acute Kidney Injury; Animals; Atorvastatin; Graft Survival; Heptanoic Acids; HMGB1 Protein; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunity, Innate; Inflammation; Kidney; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Oxidative Stress; Pyrroles; Rats; Reperfusion Injury; Toll-Like Receptor 4 | 2014 |
Inflammatory stress reduces the effectiveness of statins in the kidney by disrupting HMGCoA reductase feedback regulation.
Topics: Adaptor Proteins, Signal Transducing; Animals; Apolipoproteins E; Atorvastatin; Blotting, Western; Caseins; CD36 Antigens; Cells, Cultured; Cholesterol; Cytokines; Drug Resistance; Feedback, Physiological; Heptanoic Acids; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Kidney; Lipopolysaccharides; Male; Mesangial Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sterol Regulatory Element Binding Protein 2; Stress, Physiological; Treatment Outcome; Tumor Necrosis Factor-alpha | 2014 |
Stimulatory interactions between human coronary smooth muscle cells and dendritic cells.
Topics: Animals; Atorvastatin; Cell Adhesion; Cell Adhesion Molecules; Cell Differentiation; Cell Movement; Cellular Microenvironment; Coculture Techniques; Coronary Vessels; Cytokines; Dendritic Cells; Heptanoic Acids; Humans; Immunophenotyping; Inflammation; Male; Myocytes, Smooth Muscle; Phenotype; Pyrroles; Rats, Wistar; Rosiglitazone; Solubility; Thiazolidinediones | 2014 |
Short-term intensive atorvastatin therapy improves endothelial function partly via attenuating perivascular adipose tissue inflammation through 5-lipoxygenase pathway in hyperlipidemic rabbits.
Topics: Adipose Tissue; Animals; Arachidonate 5-Lipoxygenase; Atorvastatin; Heptanoic Acids; Hyperlipidemias; Inflammation; Lipid Metabolism; Male; Pyrroles; Rabbits | 2014 |
99mTc-cAbVCAM1-5 imaging is a sensitive and reproducible tool for the detection of inflamed atherosclerotic lesions in mice.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Atorvastatin; Female; Heptanoic Acids; Humans; Immunoglobulin Fragments; Immunohistochemistry; Inflammation; Mice; Multimodal Imaging; Pyrroles; Reference Values; Reproducibility of Results; Technetium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; Vascular Cell Adhesion Molecule-1 | 2014 |
The oxidative stress product carboxyethylpyrrole potentiates TLR2/TLR1 inflammatory signaling in macrophages.
Topics: Animals; Gene Expression Regulation; Humans; Immunity, Innate; Inflammation; Lipid Peroxidation; Macrophages; Macular Degeneration; Mice; Oxidative Stress; Pyrroles; Signal Transduction; Toll-Like Receptor 1; Toll-Like Receptor 2; Toll-Like Receptor 6 | 2014 |
Small high-density lipoprotein is associated with monocyte subsets in stable coronary artery disease.
Topics: Aged; Atherosclerosis; Atorvastatin; Blood Pressure; Coronary Angiography; Coronary Artery Disease; Cross-Sectional Studies; Female; Fluorobenzenes; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Heptanoic Acids; Humans; Inflammation; Interleukin-10; Lipids; Lipoproteins, HDL; Macrophage Colony-Stimulating Factor; Male; Middle Aged; Monocytes; Pyrimidines; Pyrroles; Risk Factors; Rosuvastatin Calcium; Sulfonamides | 2014 |
[Effect of atorvastatin on pro-inflammatory status (in vivo and in vitro) in patients with essential hypertension and metabolic syndrome].
Topics: Anticholesteremic Agents; Atorvastatin; Cytokines; Dose-Response Relationship, Drug; Drug Monitoring; Essential Hypertension; Female; Heptanoic Acids; Humans; Hypertension; Inflammation; Leukocytes, Mononuclear; Male; Metabolic Syndrome; Middle Aged; Patient Acuity; Prospective Studies; Pyrroles; Reactive Oxygen Species; Severity of Illness Index; Treatment Outcome | 2014 |
Role of inflammation in the initiation and maintenance of atrial fibrillation and the protective effect of atorvastatin in a goat model of aseptic pericarditis.
Topics: Animals; Atorvastatin; Atrial Fibrillation; Cardiac Surgical Procedures; Cytokines; Disease Models, Animal; Goats; Heart Atria; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Inflammation Mediators; Male; Pericarditis; Pyrroles | 2015 |
Rheumatoid arthritis in 2014: Exciting times for RA research.
Topics: Animals; Arthritis, Rheumatoid; Disease Models, Animal; Humans; Inflammation; Piperidines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; T-Lymphocytes, Regulatory | 2015 |
Biased agonism as a novel strategy to harness the proresolving properties of melanocortin receptors without eliciting melanogenic effects.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Calcium; Disease Models, Animal; Gene Knockout Techniques; Guanidines; HEK293 Cells; Humans; Inflammation; Macrophages, Peritoneal; Male; Melanins; Melanoma, Experimental; Mice; Neutrophils; Peritonitis; Phagocytosis; Pyrroles; Receptor, Melanocortin, Type 1; Receptor, Melanocortin, Type 3; Receptors, Melanocortin; Signal Transduction | 2015 |
An effective approach to reduce inflammation and stenosis in carotid artery: polypyrrole nanoparticle-based photothermal therapy.
Topics: Animals; Biocompatible Materials; Carotid Arteries; Carotid Stenosis; Cell Line; Cell Survival; Inflammation; Macrophages; Male; Mice; Mice, Transgenic; Nanoparticles; Phototherapy; Polymers; Pyrroles | 2015 |
Potential role of anti-VEGF targeted therapies in cervical artery dissection: A case report.
Topics: Angiogenesis Inhibitors; Aphasia; Bone Neoplasms; Carcinoma, Renal Cell; Carotid Artery, Internal, Dissection; Combined Modality Therapy; Endovascular Procedures; Hematoma; Humans; Hyperhomocysteinemia; Indoles; Infarction, Middle Cerebral Artery; Inflammation; Kidney Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Nephrectomy; Paresis; Protein Kinase Inhibitors; Pyrroles; Radiography; Radiotherapy, Adjuvant; Stents; Sunitinib; Vasa Vasorum; Vascular Endothelial Growth Factor A; Vitamin B 12 Deficiency | 2015 |
The effects of atorvastatin on antioxidant/antiinflammatory properties of HDLs in hypercholesterolemics.
Topics: Adult; Anticholesteremic Agents; Arginine; Atorvastatin; Drug Monitoring; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Inflammation; Lipoproteins, HDL; Male; Malondialdehyde; Middle Aged; Nitric Oxide; Oxidative Stress; Pyrroles; Treatment Outcome | 2015 |
Topically Administered Janus-Kinase Inhibitors Tofacitinib and Oclacitinib Display Impressive Antipruritic and Anti-Inflammatory Responses in a Model of Allergic Dermatitis.
Topics: Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents; Antipruritics; Cytokines; Dermatitis, Allergic Contact; Disease Models, Animal; Female; Inflammation; Janus Kinases; Lymph Nodes; Mice; Mice, Inbred BALB C; Piperidines; Pruritus; Pyrimidines; Pyrroles; Skin; Sulfonamides | 2015 |
Involvement of Mast Cells in α7 Nicotinic Receptor Agonist Exacerbation of Freund's Complete Adjuvant-Induced Monoarthritis in Mice.
Topics: Aconitine; Adjuvants, Immunologic; alpha7 Nicotinic Acetylcholine Receptor; Animals; Apolipoproteins E; Arthritis, Experimental; Bridged-Ring Compounds; Cell Movement; Cell Proliferation; Disease Models, Animal; Disease Progression; Freund's Adjuvant; Inflammation; Injections, Intra-Articular; Lipopolysaccharides; Male; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nicotinic Antagonists; Peptide Fragments; Pyrroles; Spiro Compounds; Xanthones | 2016 |
Role of Janus Kinase 3 in Predisposition to Obesity-associated Metabolic Syndrome.
Topics: Animals; Body Weight; Caco-2 Cells; Cytokines; Diet, High-Fat; Disease Models, Animal; Genetic Predisposition to Disease; Glucose Tolerance Test; Humans; Immunity, Innate; Inflammation; Insulin; Janus Kinase 3; Liver; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Fluorescence; Obesity; Organ Size; Piperidines; Pyrimidines; Pyrroles; Risk Factors; Signal Transduction; Toll-Like Receptors | 2015 |
Kallikrein Promotes Inflammation in Human Dental Pulp Cells Via Protease-Activated Receptor-1.
Topics: Cells, Cultured; Complement C3; Dental Pulp; Enkephalins; Humans; Inflammation; Kallikreins; Prostate-Specific Antigen; Protein Precursors; Pulpitis; Pyrroles; Quinazolines; Receptor, PAR-1; Renin | 2016 |
Role of dose exposure and inflammatory status in a single center, real-world analysis of sunitinib in patients with metastatic renal cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Cohort Studies; Disease Progression; Female; Humans; Indoles; Inflammation; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Sunitinib; Treatment Outcome | 2016 |
Targeting the IFN-γ/CXCL10 pathway in lichen planus.
Topics: Chemokine CXCL10; Chemokine CXCL9; Enzyme Inhibitors; Humans; Inflammation; Interferon-gamma; Lichen Planus; Models, Theoretical; Piperidines; Promoter Regions, Genetic; Pyrimidines; Pyrroles; Signal Transduction; Skin; Treatment Outcome | 2016 |
Comparative short-term inhalation toxicity of five organic diketopyrrolopyrrole pigments and two inorganic iron-oxide-based pigments.
Topics: Acute-Phase Proteins; Animals; Bronchioles; Bronchoalveolar Lavage Fluid; Coloring Agents; Inflammation; Inhalation Exposure; Ketones; Lung; Macrophages, Alveolar; Male; Occupational Exposure; Particle Size; Phagocytosis; Pyrroles; Rats, Wistar; Toxicity Tests, Acute | 2016 |
Distinct effects of inflammation on preconditioning and regeneration of the adult zebrafish heart.
Topics: Aminopyridines; Animals; Anti-Inflammatory Agents; Cell Cycle; Cell Proliferation; Cryopreservation; Disease Models, Animal; Heart; Inflammation; Ischemic Preconditioning, Myocardial; Leukocytes; Myocardial Infarction; Myocytes, Cardiac; Pyrroles; Regeneration; Thoracotomy; Zebrafish | 2016 |
Runt-related Transcription Factor 1 (RUNX1) Binds to p50 in Macrophages and Enhances TLR4-triggered Inflammation and Septic Shock.
Topics: Animals; Benzodiazepinones; Core Binding Factor Alpha 2 Subunit; Inflammation; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Macrophages, Peritoneal; Mice; NF-kappa B p50 Subunit; Protein Binding; Pyrroles; RAW 264.7 Cells; Shock, Septic; Signal Transduction; Toll-Like Receptor 4 | 2016 |
JAK inhibitor JTE-052 regulates contact hypersensitivity by downmodulating T cell activation and differentiation.
Topics: Administration, Oral; Animals; Antigen Presentation; Cell Differentiation; Cell Movement; Cell Proliferation; Croton Oil; Dendritic Cells; Dermatitis, Allergic Contact; Drug Evaluation, Preclinical; Female; Haptens; Inflammation; Interferon-gamma; Interleukin-13; Interleukin-17; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Protein Kinase Inhibitors; Pyrroles; Skin; T-Lymphocytes | 2016 |
Bacterial short-chain fatty acid metabolites modulate the inflammatory response against infectious bacteria.
Topics: Acetic Acid; Acrylamides; Aggregatibacter actinomycetemcomitans; Animals; Butyrates; Cytokines; Histone Deacetylase Inhibitors; Histone Deacetylases; Inflammation; Leukocyte Count; Male; Mice; Mice, Inbred C57BL; Neutrophils; Nylons; Pasteurellaceae Infections; Phagocytosis; Phenylenediamines; Propionates; Pyrroles | 2017 |
Tofacitinib ameliorates inflammation in a rat model of airway neutrophilia induced by inhaled LPS.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Inflammation; Janus Kinases; Lipopolysaccharides; Lung; Male; Neutrophils; Phosphorylation; Piperidines; Pneumonia; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Signal Transduction; STAT3 Transcription Factor | 2017 |
Regulatory role of the JAK STAT kinase signalling system on the IL-23/IL-17 cytokine axis in psoriatic arthritis.
Topics: Arthritis, Psoriatic; Humans; Inflammation; Interleukin-17; Interleukin-23; Janus Kinases; Piperidines; Pyrimidines; Pyrroles | 2017 |
Response to: 'Regulatory role of the JAK STAT kinase signalling system on the IL-23/IL-17 cytokine axis in psoriatic arthritis' by Raychaudhuri
Topics: Arthritis, Psoriatic; Humans; Inflammation; Interleukin-17; Interleukin-23; Janus Kinases; Piperidines; Pyrimidines; Pyrroles | 2017 |
Statin inhibits kainic acid-induced seizure and associated inflammation and hippocampal cell death.
Topics: Animals; Atorvastatin; Cell Death; Disease Models, Animal; Dose-Response Relationship, Drug; Ectodysplasins; Heptanoic Acids; Hippocampus; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Situ Nick-End Labeling; Inflammation; Interleukin-1beta; Kainic Acid; Male; Nitric Oxide Synthase Type II; Pyrroles; Rats; Rats, Sprague-Dawley; Seizures; Tumor Necrosis Factor-alpha | 2008 |
Corticotropin-releasing hormone receptor 1 antagonist blocks colonic hypersensitivity induced by a combination of inflammation and repetitive colorectal distension.
Topics: Animals; Colitis; Colon; Dilatation, Pathologic; Electromyography; Humans; Inflammation; Irritable Bowel Syndrome; Male; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Trinitrobenzenesulfonic Acid | 2008 |
Polycystic ovary syndrome, inflammation, and statins: do we have the right target?
Topics: Atorvastatin; C-Reactive Protein; Cardiovascular Diseases; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Polycystic Ovary Syndrome; Pregnancy; Pyrroles; Testosterone | 2009 |
Atorvastatin modulates Th1/Th2 response in patients with chronic heart failure.
Topics: Atorvastatin; Biomarkers; Case-Control Studies; Female; Heart Failure; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Immunoenzyme Techniques; Inflammation; Interferon-gamma; Interleukin-10; Interleukin-12; Interleukin-18; Interleukin-4; Male; Middle Aged; Pyrroles; Th1 Cells; Th2 Cells | 2009 |
Iron oxide magnetic resonance imaging for atherosclerosis therapeutic evaluation: still "rusty?".
Topics: Anticholesteremic Agents; Atorvastatin; Biomarkers; Carotid Stenosis; Ferric Compounds; Heptanoic Acids; Humans; Inflammation; Macrophages; Nanoparticles; Pyrroles | 2009 |
Inhibitory effects of sunitinib on ovalbumin-induced chronic experimental asthma in mice.
Topics: Angiogenesis Inhibitors; Animals; Asthma; Blotting, Western; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Female; Immunoglobulin E; Immunohistochemistry; Immunoprecipitation; In Vitro Techniques; Indoles; Inflammation; Interleukin-13; Interleukin-4; Lung; Mice; Mice, Inbred BALB C; Ovalbumin; Proto-Oncogene Proteins c-kit; Pyrroles; Sunitinib | 2009 |
Sedation and antinociception induced by a new pyrazolo[3,4-b]pyrrolo[3,4-d]pyridine derivative (LASSBio-873) is modulated by activation of muscarinic receptors.
Topics: Adrenergic alpha-Antagonists; Analgesics; Analysis of Variance; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; GABA Antagonists; Hot Temperature; Hyperalgesia; Hypnotics and Sedatives; Inflammation; Male; Mice; Motor Activity; Muscarinic Antagonists; Narcotic Antagonists; Pain; Pain Measurement; Pyrazoles; Pyridines; Pyrroles; Receptors, Muscarinic | 2009 |
[Effect of atorvastatin on inflammatory infiltration in the lung of rabbits with hypercholesterolemia].
Topics: Animals; Atorvastatin; Bronchoalveolar Lavage; Heptanoic Acids; Hypercholesterolemia; Inflammation; Lung; Macrophages, Alveolar; Male; NF-kappa B; Pyrroles; Rabbits; Random Allocation | 2009 |
FDG-PET can distinguish inflamed from non-inflamed plaque in an animal model of atherosclerosis.
Topics: Animals; Aorta; Atherosclerosis; Atorvastatin; Catheterization; Cholesterol, Dietary; Diagnosis, Differential; Disease Models, Animal; Fluorodeoxyglucose F18; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Macrophages; Male; Positron-Emission Tomography; Predictive Value of Tests; Pyrroles; Rabbits; Radiopharmaceuticals | 2010 |
Vascular endothelial growth factor is a key mediator in the development of T cell priming and its polarization to type 1 and type 17 T helper cells in the airways.
Topics: Allergens; Animals; Apoptosis; Asthma; Immunity, Active; Immunity, Innate; Indoles; Inflammation; Interleukin-12; Interleukin-17; Interleukin-6; Lipopolysaccharides; Lung; Mice; Mice, Inbred BALB C; Mice, Knockout; Ovalbumin; Protein Kinase Inhibitors; Pyrroles; T-Lymphocytes, Helper-Inducer; Th1 Cells; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2009 |
Atorvastatin inhibits inflammatory angiogenesis in mice through down regulation of VEGF, TNF-alpha and TGF-beta1.
Topics: Administration, Oral; Animals; Atorvastatin; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Macrophages; Male; Mice; Neovascularization, Pathologic; Pyrroles; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2010 |
18F-4V for PET-CT imaging of VCAM-1 expression in atherosclerosis.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Atorvastatin; Binding, Competitive; Cells, Cultured; Contrast Media; Disease Models, Animal; Endothelium, Vascular; Feasibility Studies; Fluorodeoxyglucose F18; Graft Rejection; Half-Life; Heart Transplantation; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Inflammation Mediators; Iopamidol; Ligands; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; Peptides; Positron-Emission Tomography; Predictive Value of Tests; Pyrroles; Radiopharmaceuticals; Reproducibility of Results; RNA, Messenger; Tissue Distribution; Tomography, X-Ray Computed; Vascular Cell Adhesion Molecule-1 | 2009 |
Apricoxib, a COX-2 inhibitor for the potential treatment of pain and cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase II as Topic; Cyclooxygenase 2 Inhibitors; Humans; Inflammation; Neoplasms; Pain; Pyrroles; Sulfonamides | 2009 |
Impact of chronic anticholesterol therapy on development of microvascular rarefaction in the metabolic syndrome.
Topics: Animals; Anticholesteremic Agents; Arterioles; Atorvastatin; Cytokines; Gemfibrozil; Heptanoic Acids; Inflammation; Male; Metabolic Syndrome; Microcirculation; Muscle, Skeletal; Nitric Oxide; Probucol; Pyrroles; Rats; Rats, Zucker; Simvastatin; Time Factors | 2009 |
Atorvastatin ameliorates inflammatory hyperalgesia in rat model of monoarticular arthritis.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Atorvastatin; Diclofenac; Female; Freund's Adjuvant; Heptanoic Acids; Hyperalgesia; Inflammation; Joints; Lower Extremity; Male; Motor Activity; Pyrroles; Rats; Rats, Wistar | 2010 |
Effect of atorvastatin and diet on non-alcoholic fatty liver disease activity score in hyperlipidemic chickens.
Topics: Animals; Atorvastatin; Chickens; Cholesterol; Disease Models, Animal; Fatty Liver; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Inflammation; Male; Pyrroles; Severity of Illness Index; Triglycerides | 2010 |
Atorvastatin downregulates monocyte CD36 expression, nuclear NFkappaB and TNFalpha levels in type 2 diabetes.
Topics: Aged; Anticholesteremic Agents; Atorvastatin; Cardiovascular Diseases; CD36 Antigens; Cells, Cultured; Diabetes Mellitus, Type 2; Down-Regulation; Female; Heptanoic Acids; Humans; Inflammation; Male; Middle Aged; Monocytes; NF-kappaB-Inducing Kinase; Protein Serine-Threonine Kinases; Pyrroles; Tumor Necrosis Factor-alpha | 2010 |
Effects of clopidogrel on vascular proliferation and apoptosis in an atherosclerotic rabbit model.
Topics: Animals; Apoptosis; Atherosclerosis; Atorvastatin; C-Reactive Protein; Catheterization; Clopidogrel; Endothelium, Vascular; Heptanoic Acids; Inflammation; Male; Platelet-Derived Growth Factor; Pyrroles; Rabbits; Random Allocation; Ticlopidine; Tunica Intima | 2010 |
Effect of atorvastatin on haemostasis, fibrinolysis and inflammation in normocholesterolaemic patients with coronary artery disease: a post hoc analysis of data from a prospective, randomized, double-blind study.
Topics: Aged; Atorvastatin; Coronary Artery Disease; Double-Blind Method; Female; Fibrinolysis; Hemostasis; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Pyrroles; Randomized Controlled Trials as Topic; Thrombin | 2010 |
Pain is a salient "stressor" that is mediated by corticotropin-releasing factor-1 receptors.
Topics: Aniline Compounds; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Corticotropin-Releasing Hormone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Hyperalgesia; Indomethacin; Inflammation; Male; Mice; Pain; Pain Threshold; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Spinal Cord Injuries; Stomach Ulcer; Stress, Psychological | 2010 |
The influence of Sam-Chil-Geun (Panax notoginseng) on the serum lipid levels and inflammations of rats with hyperlipidemia induced by poloxamer-407.
Topics: Animals; Atorvastatin; Cholesterol; Cyclooxygenase 2; Drugs, Chinese Herbal; Heptanoic Acids; Hyperlipidemias; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-1; Lipids; Male; Poloxamer; Pyrroles; Rats; Rats, Wistar; Triglycerides; Tumor Necrosis Factor-alpha | 2010 |
Heme oxygenase-1 upregulation improves lipopolysaccharide-induced acute lung injury involving suppression of macrophage migration inhibitory factor.
Topics: Acute Lung Injury; Animals; Cell Line; Cell Movement; Gene Expression Regulation; Heme Oxygenase-1; Inflammation; Intramolecular Oxidoreductases; Lipopolysaccharides; Macrophage Migration-Inhibitory Factors; Macrophages; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Pyrazines; Pyrroles; RNA, Small Interfering; Specific Pathogen-Free Organisms; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha; Up-Regulation | 2010 |
Discovery of 4-(5-(cyclopropylcarbamoyl)-2-methylphenylamino)-5-methyl-N-propylpyrrolo[1,2-f][1,2,4]triazine-6-carboxamide (BMS-582949), a clinical p38α MAP kinase inhibitor for the treatment of inflammatory diseases.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Arthritis, Rheumatoid; Biological Availability; Caco-2 Cells; Crystallography, X-Ray; Female; Humans; Hydrogen Bonding; In Vitro Techniques; Inflammation; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Microsomes, Liver; Mitogen-Activated Protein Kinase 14; Models, Molecular; Molecular Conformation; Protein Binding; Pyrroles; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship; Triazines; Tumor Necrosis Factor-alpha | 2010 |
Atorvastatin treatment affects atrial ion currents and their tachycardia-induced remodeling in rabbits.
Topics: Animals; Atorvastatin; Atrial Fibrillation; Female; Heart Atria; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Ion Channels; Oxidative Stress; Patch-Clamp Techniques; Pyrroles; Rabbits; Tachycardia; Time Factors | 2010 |
Matrix metalloproteinase-9 may be a potential therapeutic target in epilepsy.
Topics: Animals; Anti-Bacterial Agents; Atorvastatin; Epilepsy; Gene Expression Regulation, Enzymologic; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Matrix Metalloproteinase 9; Mice; Minocycline; Models, Biological; Neurons; Pyrroles; Rats; Seizures; Treatment Outcome | 2011 |
Oxidative stress induces angiogenesis by activating TLR2 with novel endogenous ligands.
Topics: Aging; Animals; Aorta; Cell Line; Cell Movement; Endothelial Cells; Hindlimb; Humans; Immunity, Innate; Inflammation; Ischemia; Ligands; Melanoma; Mice; Mice, Inbred C57BL; Myeloid Differentiation Factor 88; Neovascularization, Pathologic; Neovascularization, Physiologic; Oxidation-Reduction; Oxidative Stress; Platelet Endothelial Cell Adhesion Molecule-1; Propionates; Pyrroles; rac1 GTP-Binding Protein; Receptors, Scavenger; Signal Transduction; Toll-Like Receptor 2; Toll-Like Receptor 4; Vascular Endothelial Growth Factor A; Wound Healing | 2010 |
Effects of immunomodulatory drugs on plasma inflammatory markers in a rabbit model of atherosclerosis.
Topics: Animals; Atherosclerosis; Atorvastatin; Biomarkers; C-Reactive Protein; Cholesterol; Cholesterol, Dietary; Cholesterol, HDL; Cholesterol, LDL; Cyclosporine; Heptanoic Acids; Immunologic Factors; Inflammation; Interferon-gamma; Interleukin-6; Male; Plasma; Pyrroles; Rabbits; Tacrolimus; Triglycerides | 2011 |
EC144, a synthetic inhibitor of heat shock protein 90, blocks innate and adaptive immune responses in models of inflammation and autoimmunity.
Topics: Adaptive Immunity; Animals; Autoimmune Diseases; Cell Line; Cell Line, Transformed; Crystallography, X-Ray; Disease Models, Animal; Female; HSP90 Heat-Shock Proteins; Humans; Immunity, Innate; Immunosuppressive Agents; Inflammation; Inflammation Mediators; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Pyrimidines; Pyrroles; Rats | 2011 |
[Atorvastatin and oxidized low density lipoprotein antibody. Relationship to age].
Topics: Adult; Age Factors; Aged; Atherosclerosis; Atorvastatin; Autoantibodies; Autoantigens; Blood Glucose; C-Reactive Protein; Creatinine; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Inflammation; Lipid Peroxidation; Lipids; Lipoproteins, LDL; Male; Middle Aged; Pyrroles; Risk Factors; Waist Circumference | 2011 |
Atorvastatin improves survival in septic rats: effect on tissue inflammatory pathway and on insulin signaling.
Topics: Adipose Tissue; Animals; Atorvastatin; Glucose; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Insulin; Interleukin-6; Liver; Male; Muscles; Pyrroles; Rats; Rats, Wistar; Sepsis; Signal Transduction; Tumor Necrosis Factor-alpha | 2010 |
Synthesis and molecular modeling studies of anti-inflammatory active 1H-pyrrolizine-5-carboxamides.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Diclofenac; Disease Models, Animal; Edema; Female; Heterocyclic Compounds; Inflammation; Male; Models, Molecular; Pyrroles; Rats; Rats, Wistar; Stomach Ulcer; Structure-Activity Relationship | 2011 |
The effect of atorvastatin on mRNA levels of inflammatory genes expression in human peripheral blood lymphocytes by DNA microarray.
Topics: Atorvastatin; Chemokines; Cytokines; Down-Regulation; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Lymphocytes; Oligonucleotide Array Sequence Analysis; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2011 |
Study of Atorvastatin in experimental allergic airway inflammation in mice.
Topics: Animals; Anti-Inflammatory Agents; Atorvastatin; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cholesterol; Cytokines; Dexamethasone; Drug Interactions; Heptanoic Acids; Immunoglobulin E; Inflammation; Leukocytes; Male; Mice; Ovalbumin; Pyrroles; Respiratory System | 2011 |
Statins exert differential effects on angiotensin II-induced atherosclerosis, but no benefit for abdominal aortic aneurysms.
Topics: Angiotensin II; Animal Feed; Animals; Anti-Inflammatory Agents; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Atorvastatin; Blood Pressure; Fluorobenzenes; Gene Expression Regulation; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Mice; Mice, Inbred C57BL; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Sulfonamides | 2011 |
Suppression of inflammatory response and endothelial nitric oxide synthase downregulation in hyperlipidaemic C57BL/6J mice by eugenosedin-A.
Topics: Animals; Anti-Inflammatory Agents; Aorta; Atorvastatin; Dietary Fats; Down-Regulation; Endothelium, Vascular; Female; Heptanoic Acids; Hyperlipidemias; Inflammation; Interferon-gamma; Liver; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Nitric Oxide; Nitric Oxide Synthase Type III; Obesity; Piperazines; Pyrroles; Random Allocation; RNA, Messenger; Tumor Necrosis Factor-alpha | 2011 |
Evaluation of anti-inflammatory, anti-nociceptive, and anti-ulcerogenic activities of novel synthesized thiazolyl and pyrrolyl steroids.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Carrageenan; Disease Models, Animal; Edema; Inflammation; Pain; Pyrroles; Rats; Rats, Sprague-Dawley; Steroids; Stomach Ulcer; Thiazoles; Ulcer | 2011 |
IL-1β and TNFα-initiated IL-6-STAT3 pathway is critical in mediating inflammatory cytokines and RANKL expression in inflammatory arthritis.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Chronic Disease; Enzyme Inhibitors; Fibroblasts; Gene Expression; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Joints; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Osteoclasts; Piperidines; Pyrimidines; Pyrroles; RANK Ligand; Signal Transduction; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha | 2011 |
Atorvastatin suppresses inflammatory response induced by oxLDL through inhibition of ERK phosphorylation, IκBα degradation, and COX-2 expression in murine macrophages.
Topics: Animals; Anti-Inflammatory Agents; Atorvastatin; Cell Line; Cell Shape; Chemokines; Cyclooxygenase 2; Gene Expression; Gene Expression Regulation, Enzymologic; Heptanoic Acids; I-kappa B Proteins; Inflammation; Lipoproteins, LDL; Macrophages; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Processing, Post-Translational; Proteolysis; Pyrroles | 2012 |
Pyrrole alkanoic acid derivatives as nuisance inhibitors of microsomal prostaglandin E2 synthase-1.
Topics: Cell Line, Tumor; Enzyme Inhibitors; Humans; Inflammation; Inhibitory Concentration 50; Intramolecular Oxidoreductases; Magnetic Resonance Spectroscopy; Microsomes; Molecular Structure; Octoxynol; Propionates; Prostaglandin-E Synthases; Pyrroles; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship | 2012 |
Phospholipase A2 enzymes, high-dose atorvastatin, and prediction of ischemic events after acute coronary syndromes.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acute Coronary Syndrome; Aged; Atherosclerosis; Atorvastatin; Biomarkers; C-Reactive Protein; Double-Blind Method; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hypercholesterolemia; Inflammation; Lipoproteins; Male; Middle Aged; Multicenter Studies as Topic; Myocardial Ischemia; Oxidation-Reduction; Phospholipases A2, Secretory; Pyrroles; Randomized Controlled Trials as Topic; Retrospective Studies; Risk; Risk Factors; Survival Analysis | 2012 |
Continuation of statin therapy in patients with presumed infection.
Topics: Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Pyrroles; Sepsis | 2012 |
Anti-inflammatory and anti-arthritic effects of new synthetic 3-(4-hydroxyphenyl)-4-(4-thiomethoxyphenyl)-1H-pyrrole-2,5-dione.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Carrageenan; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Inflammation; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Macrophages; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Pyrroles; Rats; Rats, Sprague-Dawley | 2012 |
Nitric oxide enhances the anti-inflammatory and anti-atherogenic activity of atorvastatin in a mouse model of accelerated atherosclerosis.
Topics: Animals; Anti-Inflammatory Agents; Anticholesteremic Agents; Atherosclerosis; Atorvastatin; Disease Models, Animal; Heptanoic Acids; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Pyrroles; Receptors, LDL | 2012 |
Licofelone inhibits interleukin-18-induced pro-inflammatory cytokine release and cellular proliferation in human mesangial cells.
Topics: Arachidonate 5-Lipoxygenase; Blotting, Western; Cell Line; Cell Proliferation; Chemokine CCL2; Chromatography, High Pressure Liquid; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; Interferon-gamma; Interleukin-18; Lipoxygenase Inhibitors; Mesangial Cells; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyrroles; Signal Transduction | 2012 |
Atorvastatin inhibits pancreatic carcinogenesis and increases survival in LSL-KrasG12D-LSL-Trp53R172H-Pdx1-Cre mice.
Topics: Animals; Atorvastatin; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Epoxide Hydrolases; Heptanoic Acids; Homeodomain Proteins; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Ki-67 Antigen; Mice; Pancreas; Pancreatic Neoplasms; Phosphorylation; Prenylation; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Pyrroles; Trans-Activators; Transcriptome; Tumor Suppressor Protein p53 | 2013 |
Potentiation of the P2X3 ATP receptor by PAR-2 in rat dorsal root ganglia neurons, through protein kinase-dependent mechanisms, contributes to inflammatory pain.
Topics: Adenosine Triphosphate; Animals; Carbazoles; Colforsin; Cyclic AMP-Dependent Protein Kinases; Ganglia, Spinal; Indoles; Inflammation; Male; Maleimides; MAP Kinase Signaling System; Membrane Potentials; Neurons; Pain; Phosphorylation; Protein Kinase C; Protein Transport; Purinergic P2X Receptor Agonists; Purinergic P2X Receptor Antagonists; Pyrroles; Rats, Sprague-Dawley; Receptor, PAR-2; Receptors, Purinergic P2X3; Tetradecanoylphorbol Acetate | 2012 |
Synergistic inhibition of interleukin-6 production in adipose stem cells by tart cherry anthocyanins and atorvastatin.
Topics: Adipose Tissue; Anthocyanins; Anti-Inflammatory Agents; Atorvastatin; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Fruit; Glucosides; Heptanoic Acids; Herb-Drug Interactions; Humans; Inflammation; Interleukin-6; Lipopolysaccharides; Phytotherapy; Plant Extracts; Prunus; Pyrroles; Stem Cells | 2012 |
Atorvastatin and pitavastatin reduce senile plaques and inflammatory responses in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Atorvastatin; Brain; Disease Models, Animal; Female; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Inflammation; Mice; Mice, Transgenic; Plaque, Amyloid; Pyrroles; Quinolines | 2012 |
Regulation of inflammatory responses in tumor necrosis factor-activated and rheumatoid arthritis synovial macrophages by JAK inhibitors.
Topics: Animals; Arthritis, Rheumatoid; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Humans; In Vitro Techniques; Inflammation; Interleukin-6; Janus Kinases; Macrophages; Mice; Mice, Inbred C57BL; NF-kappa B; NFATC Transcription Factors; Nitriles; Piperidines; Proto-Oncogene Proteins c-jun; Pyrazoles; Pyrimidines; Pyrroles; Signal Transduction; STAT1 Transcription Factor; Synovial Membrane; Tumor Necrosis Factor-alpha | 2012 |
Atorvastatin preconditioning improves the forward blood flow in the no-reflow rats.
Topics: Animals; Atorvastatin; Echocardiography; Fibrinogen; Fibrosis; Hemodynamics; Heptanoic Acids; Inflammation; Male; Microcirculation; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Pyrroles; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Tumor Necrosis Factor-alpha | 2014 |
Effects of statins on oxidative stress and primed polymorphonuclear leukocytes in hyperlipidemic patients.
Topics: Adult; Apoptosis; Atorvastatin; Biomarkers; CD11b Antigen; Cells, Cultured; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Inflammation; Leukocyte Count; Male; Neutrophils; Oxidative Stress; Phorbol Esters; Pyrroles; Superoxides | 2012 |
Surface engineering of titanium substrates with chitosan-atorvastatin conjugate for reduced inflammation responses and improved cytocompatibility.
Topics: Acid Phosphatase; Animals; Atorvastatin; Biocompatible Materials; Cells, Immobilized; Chitosan; Cytokines; Dogs; Fluorescent Antibody Technique; Heptanoic Acids; Human Umbilical Vein Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; L-Lactate Dehydrogenase; Macrophages; Magnetic Resonance Spectroscopy; Microscopy, Electron, Scanning; Nitric Oxide; Proteins; Pyrroles; Reactive Oxygen Species; Surface Properties; Titanium | 2013 |
Licofelone modulates neuroinflammation and attenuates mechanical hypersensitivity in the chronic phase of spinal cord injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Female; Gas Chromatography-Mass Spectrometry; Hindlimb; Hot Temperature; Hyperalgesia; Inflammation; Leukotriene B4; Locomotion; Metabolomics; Oxidative Stress; Physical Stimulation; Pyrroles; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries | 2013 |
Resveratrol protects against atherosclerosis, but does not add to the antiatherogenic effect of atorvastatin, in APOE*3-Leiden.CETP mice.
Topics: Animals; Atherosclerosis; Atorvastatin; Biomarkers; Cholesterol, Dietary; Cholesterol, LDL; Drug Synergism; Female; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Mice; Mice, Transgenic; Oxidative Stress; Pyrroles; Resveratrol; Stilbenes | 2013 |
The effect of atorvastatin and simvastatin on vitamin D, oxidative stress and inflammatory marker concentrations in patients with type 2 diabetes: a crossover study.
Topics: Atorvastatin; Biomarkers; C-Reactive Protein; Cross-Over Studies; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Lipids; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Pyrroles; Simvastatin; Treatment Outcome; Vitamin D | 2013 |
Tissue reaction to polypyrrole-coated polyester fabrics: an in vivo study in rats.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Collagen; Inflammation; Magnetic Resonance Imaging; Male; Materials Testing; Muscles; Polyesters; Polymers; Pyrroles; Rats; Rats, Sprague-Dawley; Textiles | 2002 |
The effect of statins on mRNA levels of genes related to inflammation, coagulation, and vascular constriction in HUVEC. Human umbilical vein endothelial cells.
Topics: Atorvastatin; Blood Coagulation; Cells, Cultured; Endothelium, Vascular; Heptanoic Acids; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Oligonucleotide Array Sequence Analysis; Pyrroles; Quinolines; Receptors, LDL; RNA, Messenger; Vasoconstriction | 2002 |
HMG-CoA reductase inhibitors regulate inflammatory transcription factors in human endothelial and vascular smooth muscle cells.
Topics: Atorvastatin; Cell Line; Cell Survival; Down-Regulation; Endothelial Growth Factors; Endothelium, Vascular; Gene Expression Regulation; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoxia-Inducible Factor 1, alpha Subunit; I-kappa B Proteins; Inflammation; Lovastatin; Muscle, Smooth, Vascular; NF-kappa B; NF-KappaB Inhibitor alpha; Plasminogen Activator Inhibitor 1; Protein Binding; Proto-Oncogene Proteins c-jun; Pyrroles; RNA, Messenger; Simvastatin; Transcription Factor AP-1; Transcription Factors; Vascular Endothelial Growth Factor A | 2003 |
Atorvastatin limits the pro-inflammatory response of rat aortic smooth muscle cells to thrombin.
Topics: Animals; Aorta, Thoracic; Atorvastatin; Dose-Response Relationship, Drug; Heptanoic Acids; Humans; Inflammation; Male; Mice; Muscle, Smooth, Vascular; Pyrroles; Rats; Rats, Wistar; Thrombin | 2003 |
C-reactive protein is not only an inflammatory marker but also a direct cause of cardiovascular diseases.
Topics: Acute-Phase Reaction; Aspirin; Atorvastatin; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Clinical Trials as Topic; Coronary Artery Disease; Heptanoic Acids; Humans; Incidence; Inflammation; Interleukin-6; Lovastatin; Pravastatin; Predictive Value of Tests; Pyrroles; Risk Factors; Simvastatin | 2004 |
In vivo evaluation of a novel electrically conductive polypyrrole/poly(D,L-lactide) composite and polypyrrole-coated poly(D,L-lactide-co-glycolide) membranes.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Biocompatible Materials; Biodegradation, Environmental; Collagen; Electric Conductivity; Fibrin; Immunohistochemistry; Inflammation; Lactic Acid; Macrophages; Male; Materials Testing; Membranes, Artificial; Microscopy, Electron, Scanning; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Polytetrafluoroethylene; Prostheses and Implants; Pyrroles; Rats; Rats, Sprague-Dawley; Sterilization; Tissue Fixation | 2004 |
Statins inhibit in vitro calcification of human vascular smooth muscle cells induced by inflammatory mediators.
Topics: Alkaline Phosphatase; Atorvastatin; Calcinosis; Dose-Response Relationship, Drug; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Mevalonic Acid; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Polyisoprenyl Phosphates; Pyridines; Pyrroles; Sesquiterpenes | 2004 |
[Endothelial dysfunction, inflammation and statins: new evidences].
Topics: Animals; Anticholesteremic Agents; Atorvastatin; C-Reactive Protein; Coronary Circulation; Endothelium, Vascular; Follow-Up Studies; Heptanoic Acids; Humans; Hypercholesterolemia; Inflammation; Interleukin-6; Pravastatin; Pyrroles; Rabbits; Time Factors | 2004 |
Effect of low dose atorvastatin versus diet-induced cholesterol lowering on atherosclerotic lesion progression and inflammation in apolipoprotein E*3-Leiden transgenic mice.
Topics: Animals; Anticholesteremic Agents; Aorta; Apolipoprotein E3; Apolipoproteins E; Arteriosclerosis; Atorvastatin; Biomarkers; C-Reactive Protein; Cholesterol; Diet; Diet, Atherogenic; Drug Administration Schedule; Female; Heptanoic Acids; Inflammation; Male; Mice; Mice, Transgenic; Pyrroles; Serum Amyloid A Protein | 2005 |
Effect of licofelone against NSAIDs-induced gastrointestinal ulceration and inflammation.
Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Female; Humans; Indomethacin; Inflammation; Leukotriene B4; Lipid Peroxidation; Male; Mesentery; Mice; Neutrophils; Pyrroles; Rats; Stomach Ulcer; Time Factors | 2005 |
Atorvastatin affects leukocyte gene expression in dyslipidemia patients: in vivo regulation of hemostasis, inflammation and apoptosis.
Topics: Adult; Anticholesteremic Agents; Apoptosis; Atorvastatin; Cholesterol; Cluster Analysis; Gene Expression Regulation; Hemostasis; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Inflammation; Leukocytes; Leukocytes, Mononuclear; Lipid Metabolism; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Pyrroles; Receptors, LDL; Reverse Transcriptase Polymerase Chain Reaction; RNA; Time Factors | 2005 |
Dual inhibition of cyclo-oxygenases and 5-lipoxygenase: a novel therapeutic approach to inflammation?
Topics: Acetates; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Inflammation; Lipoxygenase Inhibitors; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrroles | 2005 |
Effects of atorvastatin on inflammation and oxidative stress.
Topics: Atorvastatin; C-Reactive Protein; Cholesterol, LDL; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Inflammation; Insulin Resistance; Isoprostanes; Middle Aged; Oxidative Stress; Pyrroles; Tunica Intima | 2005 |
99mTc-interleukin-2 scintigraphy for the in vivo imaging of vulnerable atherosclerotic plaques.
Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Atherosclerosis; Atorvastatin; Carotid Arteries; Diet, Atherogenic; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Interleukin-2; Male; Middle Aged; Pyrroles; Radionuclide Imaging; Technetium | 2006 |
Effect of statin therapy on serum trace element status in dyslipidaemic subjects.
Topics: Adult; Antioxidants; Atorvastatin; Blood Chemical Analysis; Ceruloplasmin; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Inflammation; Lipids; Male; Middle Aged; Pyrroles; Simvastatin; Trace Elements | 2005 |
Active metabolite of atorvastatin inhibits membrane cholesterol domain formation by an antioxidant mechanism.
Topics: Antioxidants; Apoptosis; Atherosclerosis; Atorvastatin; Cell Membrane; Cholesterol, LDL; Dose-Response Relationship, Drug; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Inflammation; Lipid Peroxidation; Membrane Lipids; Models, Biological; Oxidative Stress; Pyrroles; X-Ray Diffraction | 2006 |
Statin-induced proinflammatory response in mitogen-activated peripheral blood mononuclear cells through the activation of caspase-1 and IL-18 secretion in monocytes.
Topics: Amino Acid Chloromethyl Ketones; Antibodies; Atorvastatin; Caspase 1; CD28 Antigens; CD3 Complex; Cells, Cultured; Enzyme Activation; Heptanoic Acids; Humans; Inflammation; Interferon-gamma; Interleukin-1; Interleukin-12; Interleukin-18; Mevalonic Acid; Mitosis; Monocytes; Pyrroles; Simvastatin; Solubility; T-Lymphocytes | 2006 |
Atorvastatin and glatiramer acetate: new hope in MS?
Topics: Adjuvants, Immunologic; Animals; Anticholesteremic Agents; Atorvastatin; Clinical Trials as Topic; Disease Models, Animal; Drug Therapy, Combination; Glatiramer Acetate; Heptanoic Acids; Humans; Immunotherapy; Inflammation; Multiple Sclerosis; Peptides; Pyrroles | 2006 |
Structure-activity relationships of 1,5-biaryl pyrroles as EP1 receptor antagonists.
Topics: Analgesics; Animals; Benzoates; Biological Availability; Cyclohexanes; Cyclopentanes; Inflammation; Ligands; Pain; Pyrroles; Rats; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Structure-Activity Relationship | 2006 |
Effects of preoperative statin therapy on cytokines after cardiac surgery.
Topics: Aged; Anti-Inflammatory Agents; Atorvastatin; Cardiopulmonary Bypass; Coronary Artery Bypass; Female; Heart Arrest, Induced; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Interleukin-10; Interleukin-6; Male; Postoperative Complications; Pravastatin; Prospective Studies; Pyrroles; Simvastatin; Time Factors | 2006 |
Statin treatment is not associated with consistent alterations in inflammatory status of carotid atherosclerotic plaques: a retrospective study in 378 patients undergoing carotid endarterectomy.
Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Atherosclerosis; Atorvastatin; Carotid Arteries; Carotid Artery Diseases; Cytokines; Dose-Response Relationship, Drug; Endarterectomy, Carotid; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Inflammation; Macrophages; Peptide Hydrolases; Phenotype; Pravastatin; Pyrroles; Retrospective Studies; Simvastatin | 2006 |
Atorvastatin inhibits inflammatory hypernociception.
Topics: Animals; Atorvastatin; Bradykinin; Cholesterol; Cytokines; Dinoprostone; Enzyme Inhibitors; Heptanoic Acids; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperalgesia; Inflammation; Interleukin-1; Lipopolysaccharides; Male; Mice; Nitric Oxide Synthase; Pain Measurement; Pyrroles; Skin | 2006 |
Tubulointerstitial macrophage accumulation is regulated by sequentially expressed osteopontin and macrophage colony-stimulating factor: implication for the role of atorvastatin.
Topics: Animals; Atorvastatin; Cell Proliferation; Gene Expression Regulation; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Inflammation; Kidney Tubules; Lipids; Macrophage Colony-Stimulating Factor; Macrophages; Osteopontin; Pyrroles; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction | 2006 |
The anti-atherosclerotic effects of lipid lowering with atorvastatin in patients with hypercholesterolemia.
Topics: Aged; Anticholesteremic Agents; Atherosclerosis; Atorvastatin; C-Reactive Protein; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Inflammation; Lipids; Male; Middle Aged; Pyrroles; Time Factors; Tunica Intima; Tunica Media | 2006 |
The lipoxygenase-cyclooxygenase inhibitor licofelone prevents thromboxane A2-mediated cardiovascular derangement triggered by the inflammatory peptide fMLP in the rabbit.
Topics: Acetates; Animals; Aspirin; Blood Pressure; Cyclooxygenase Inhibitors; Disease Models, Animal; Electrocardiography; Heart Rate; Inflammation; Lactones; Leukotriene B4; Lipoxygenase Inhibitors; Male; Myocardial Ischemia; N-Formylmethionine Leucyl-Phenylalanine; Pyrroles; Rabbits; Sulfones; Thromboxane A2; Time Factors | 2006 |
Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Azepines; Carrageenan; Caspase 3; Cyclin-Dependent Kinases; Enzyme Inhibitors; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Inflammation; Male; Mice; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Neutrophils; Pleurisy; Proto-Oncogene Proteins c-bcl-2; Purines; Pyrroles; Roscovitine | 2006 |
1,5-Biaryl pyrrole derivatives as EP1 receptor antagonists: Structure-activity relationships of 4- and 5-substituted benzoic acid derivatives.
Topics: Animals; Benzoates; CHO Cells; Cricetinae; Cricetulus; Inflammation; Pain; Pyrroles; Rats; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Structure-Activity Relationship | 2007 |
The effect of early statin treatment on inflammation and cardiac events in acute coronary syndrome patients with low-density lipoprotein cholesterol.
Topics: Acute Disease; Aged; Anticholesteremic Agents; Atorvastatin; C-Reactive Protein; Case-Control Studies; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Female; Follow-Up Studies; Heptanoic Acids; Humans; Inflammation; Male; Middle Aged; Myocardial Infarction; Prognosis; Pyrroles; Serum Amyloid A Protein; Statistics as Topic; Syndrome; Treatment Outcome; Triglycerides | 2006 |
Effect of clopidogrel on the inflammatory progression of early atherosclerosis in rabbits model.
Topics: Animals; Aspirin; Atherosclerosis; Atorvastatin; Chemokine CCL2; Clopidogrel; Diet, Atherogenic; Disease Models, Animal; Femoral Artery; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Intercellular Adhesion Molecule-1; Male; P-Selectin; Platelet Aggregation Inhibitors; Pyrroles; Rabbits; Ticlopidine; Vascular Cell Adhesion Molecule-1 | 2007 |
Pyrrolopyridine inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2).
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Crystallography, X-Ray; Humans; Inflammation; Intracellular Signaling Peptides and Proteins; Models, Molecular; Protein Serine-Threonine Kinases; Pyridines; Pyrroles; Rats; Structure-Activity Relationship; Tumor Necrosis Factor-alpha; U937 Cells | 2007 |
Anti-inflammatory effects of atorvastatin improve left ventricular function in experimental diabetic cardiomyopathy.
Topics: Animals; Anti-Inflammatory Agents; Atorvastatin; Collagen; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Heart; Heptanoic Acids; Inflammation; Myocardium; Pyrroles; Rats; Rats, Sprague-Dawley; Ventricular Dysfunction, Left; Ventricular Function, Left | 2007 |
Low-dose treatment with atorvastatin leads to anti-oxidative and anti-inflammatory effects in diabetes mellitus.
Topics: Animals; Anti-Inflammatory Agents; Anticholesteremic Agents; Antioxidants; Atorvastatin; Diabetes Mellitus, Experimental; Endothelium, Vascular; Gene Expression; Heptanoic Acids; Inflammation; Inflammation Mediators; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NADPH Oxidases; Oxidative Stress; Phosphorylation; Pyrroles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Streptozocin; Transcription Factor RelA; Vasodilation | 2007 |
E-selectin and TFPI are associated with carotid intima-media thickness in stable IHD patients: the baseline findings of the MIAMI study.
Topics: Atorvastatin; Biomarkers; C-Reactive Protein; Carotid Artery Diseases; Cholesterol; E-Selectin; Endothelium, Vascular; Female; Fibrinogen; Heptanoic Acids; Humans; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-6; Interleukin-8; Lipoproteins; Male; Middle Aged; Prospective Studies; Pyrroles; Thromboplastin; Triglycerides; Tumor Necrosis Factor-alpha; Tunica Intima; Vascular Cell Adhesion Molecule-1; von Willebrand Factor | 2008 |
Preclinical pharmacology profile of CS-706, a novel cyclooxygenase-2 selective inhibitor, with potent antinociceptive and anti-inflammatory effects.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Arthritis; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Inflammation; Inhibitory Concentration 50; Pain; Pain Measurement; Pyrroles; Rats; Rats, Inbred Lew; Rats, Wistar; Sulfonamides | 2008 |
Antiangiogenic treatment with sunitinib ameliorates inflammatory infiltrate, fibrosis, and portal pressure in cirrhotic rats.
Topics: Angiogenesis Inhibitors; Animals; Cells, Cultured; Disease Models, Animal; Hypertension, Portal; Indoles; Inflammation; Liver Cirrhosis; Male; Portal Pressure; Pyrroles; Rats; Rats, Wistar; Sunitinib | 2007 |
A pivotal role for interleukin-4 in atorvastatin-associated neuroprotection in rat brain.
Topics: Animals; Atorvastatin; Brain Chemistry; Cholesterol; Gene Expression Regulation; Heptanoic Acids; Hippocampus; Histocompatibility Antigens Class II; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Interferon-gamma; Interleukin-1beta; Interleukin-4; Lipopolysaccharides; Male; Mice; Mice, Knockout; Microglia; Neuroprotective Agents; Pyrroles; Rats; Rats, Wistar | 2008 |
Monocyte chemoattractant protein-1 expression is enhanced by granulocyte-macrophage colony-stimulating factor via Jak2-Stat5 signaling and inhibited by atorvastatin in human monocytic U937 cells.
Topics: Atorvastatin; Chemokine CCL2; Down-Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Janus Kinase 2; Monocytes; Pyrroles; Response Elements; RNA Stability; RNA, Messenger; Signal Transduction; STAT5 Transcription Factor; Transcription, Genetic; U937 Cells; Up-Regulation | 2008 |
Oxidative damage-induced inflammation initiates age-related macular degeneration.
Topics: Aging; Animals; Antibodies; Antigens; Bruch Membrane; Complement C3d; Immunization; Inflammation; Macular Degeneration; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Oxidative Stress; Pigment Epithelium of Eye; Protein Transport; Pyrroles; Time Factors; Titrimetry | 2008 |
Anti-inflammatory effects of combined treatment with acetyl salicylic acid and atorvastatin in haemodialysis patients affected by Normal Weight Obese syndrome.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Aspirin; Atorvastatin; Body Fat Distribution; Body Mass Index; Body Weight; C-Reactive Protein; Cardiovascular Diseases; Cholesterol, HDL; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Inflammation; Kidney Failure, Chronic; Lipid Metabolism; Male; Middle Aged; Nutrition Assessment; Obesity; Prealbumin; Pyrroles; Renal Dialysis; Serum Albumin; Syndrome | 2008 |
Pleiotropic effects of atorvastatin in heart failure: role in oxidative stress, inflammation, endothelial function, and exercise capacity.
Topics: Aged; Atorvastatin; Biomarkers; Brachial Artery; Chronic Disease; Endothelium, Vascular; Exercise Tolerance; Female; Heart Failure; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Middle Aged; Oxidative Stress; Prospective Studies; Pyrroles; Time Factors; Vasodilation; Walking | 2008 |
Plasmin is involved in inflammation via protease-activated receptor-1 activation in human dental pulp.
Topics: Adult; Calcium; Cells, Cultured; Dental Pulp; Dinoprostone; Fibrinolysin; Humans; Inflammation; Interleukin-8; Peptides; Pyrroles; Quinazolines; Receptor, PAR-1; RNA, Messenger | 2008 |
Biphasic effects of atorvastatin on inflammation.
Topics: Animals; Anti-Inflammatory Agents; Anticholesteremic Agents; Atorvastatin; Carrageenan; Edema; Heptanoic Acids; Hindlimb; Inflammation; Male; Mevalonic Acid; Mice; Pyrroles; Rats; Rats, Wistar | 2008 |
Treating residual cardiovascular risk: will lipoprotein-associated phospholipase A2 inhibition live up to its promise?
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Anti-Inflammatory Agents; Anticholesteremic Agents; Atorvastatin; Coronary Artery Disease; Heptanoic Acids; Humans; Inflammation; Pyrroles | 2008 |
Torcetrapib does not reduce atherosclerosis beyond atorvastatin and induces more proinflammatory lesions than atorvastatin.
Topics: Animals; Atherosclerosis; Atorvastatin; Cholesterol Ester Transfer Proteins; Drug Synergism; Heptanoic Acids; Inflammation; Mice; Mice, Inbred Strains; Pyrroles; Quinolines | 2008 |
Inhibition of development of experimental aortic abdominal aneurysm in rat model by atorvastatin through inhibition of macrophage migration.
Topics: Animals; Anticholesteremic Agents; Aortic Aneurysm, Abdominal; Atorvastatin; Cell Movement; Collagen; Disease Models, Animal; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Macrophages; Pancreatic Elastase; Pyrroles; Rats; Rats, Wistar; Treatment Outcome | 2009 |
Short term effects of atorvastatin on endothelial functions and oxidized LDL levels in patients with type 2 diabetes.
Topics: Atherosclerosis; Atorvastatin; Biomarkers; Brachial Artery; Carotid Arteries; Cholesterol, LDL; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Heptanoic Acids; Humans; Inflammation; Lipids; Lipoproteins, LDL; Male; Middle Aged; Pyrroles; Tunica Intima | 2008 |
Tolmetin uptake into inflamed tissue in the rat.
Topics: Administration, Topical; Animals; Inflammation; Male; Muscles; Pyrroles; Rats; Rats, Inbred Strains; Tolmetin | 1983 |
Furunculosis and hidradenitis suppurativa response.
Topics: Adolescent; Adult; Child; Child, Preschool; Furunculosis; Humans; Inflammation; Pyrroles; Sweat Gland Diseases; Tolmetin | 1984 |
A non-peptide NK1-receptor antagonist, RP 67580, inhibits neurogenic inflammation postsynaptically.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Capsaicin; Electric Stimulation; Indoles; Inflammation; Injections, Intravenous; Isoindoles; Male; Morphine; Mucus; Nasal Mucosa; Pyrroles; Rats; Rats, Wistar; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Synapses; Thiophenes; Xylenes | 1993 |
Further evidence that substance P is a mediator of both neurogenic inflammation and pain: two phenomena inhibited either by postsynaptic blockade of NK1 receptors or by presynaptic action of opioid receptor agonists.
Topics: Analgesics; Animals; Anticonvulsants; Electric Stimulation; Formaldehyde; Indoles; Inflammation; Isoindoles; Male; Mice; Mice, Inbred Strains; Morphine; Pain; Peripheral Nerves; Pyrroles; Rats; Rats, Sprague-Dawley; Substance P; Thiophenes | 1993 |
Effect of aminoethylpyrroles on carrageenan-induced inflammation and on lipid peroxidation in rats: some structural aspects.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Carrageenan; Edema; Inflammation; Lipid Peroxidation; Male; Microsomes, Liver; Pyrroles; Rats; Rats, Inbred F344; Structure-Activity Relationship | 1994 |
[Synthesis and biological activity of 1,5-diaryl-3-alkylamino-4-carboxymethyl-2,5-dihydropyrrol-2-ones and 1,5-diaryl-4-carboxymethyltetrahydropyrrol-2,3-diones].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Inflammation; Lethal Dose 50; Mice; Pyrroles; Pyrrolidinones; Rats | 1993 |
In vivo and in vitro characterization of antalarmin, a nonpeptide corticotropin-releasing hormone (CRH) receptor antagonist: suppression of pituitary ACTH release and peripheral inflammation.
Topics: Adrenocorticotropic Hormone; Animals; Binding, Competitive; Carrageenan; Cerebellum; Corticotropin-Releasing Hormone; Frontal Lobe; Inflammation; Injections, Subcutaneous; Male; Myocardium; Pituitary Gland; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Sheep | 1996 |
A serine elastase inhibitor reduces inflammation and fibrosis and preserves cardiac function after experimentally-induced murine myocarditis.
Topics: Administration, Oral; Animals; Cardiovirus Infections; Disease Models, Animal; Encephalomyocarditis virus; Fibrosis; Heart; Inflammation; Male; Mice; Mice, Inbred DBA; Microcirculation; Myocarditis; Myocardium; Perfusion; Peroxidase; Pyrroles; Serine Proteinase Inhibitors; Sulfonamides | 1998 |
HMG-CoA reductase inhibition by atorvastatin reduces neointimal inflammation in a rabbit model of atherosclerosis.
Topics: Animals; Atorvastatin; Chemokine CCL2; Coronary Artery Disease; Disease Models, Animal; Evaluation Studies as Topic; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; NF-kappa B; Pyrroles; Rabbits; Random Allocation; Tunica Intima | 1998 |
Atorvastatin reduces NF-kappaB activation and chemokine expression in vascular smooth muscle cells and mononuclear cells.
Topics: Animals; Atorvastatin; Base Sequence; Blotting, Western; Cells, Cultured; Chemokines; Coronary Artery Disease; Coronary Vessels; Gene Expression; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Molecular Sequence Data; Monocytes; Muscle, Smooth, Vascular; NF-kappa B; Polymerase Chain Reaction; Pyrroles; Rats; Reproducibility of Results; Sensitivity and Specificity | 1999 |
Synthesis and characterization of polypyrrole-hyaluronic acid composite biomaterials for tissue engineering applications.
Topics: Animals; Biocompatible Materials; Biomedical Engineering; Blood Vessels; Bone Regeneration; Electric Conductivity; Hyaluronic Acid; Inflammation; Male; Microscopy, Electron, Scanning; Neovascularization, Pathologic; Nerve Regeneration; PC12 Cells; Polymers; Prostheses and Implants; Pyrroles; Rats; Rats, Sprague-Dawley | 2000 |
The state of the heart. If you thought cholesterol was all you had to worry about, better think again.
Topics: American Heart Association; Anticholesteremic Agents; Atorvastatin; Cholesterol; Coronary Disease; Folic Acid; Heptanoic Acids; Humans; Inflammation; Pyrroles; United States | 2000 |
Corticotropin-releasing hormone promotes blastocyst implantation and early maternal tolerance.
Topics: Animals; Apoptosis; Blastocyst; Cells, Cultured; Corticotropin-Releasing Hormone; Decidua; Embryo Implantation; Endometrium; Fas Ligand Protein; fas Receptor; Female; Gene Expression Regulation; Histocompatibility; Humans; Inflammation; Litter Size; Membrane Glycoproteins; Pregnancy; Pyrimidines; Pyrroles; Rats; Rats, Inbred F344; Rats, Nude; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; T-Lymphocyte Subsets; Trophoblasts | 2001 |
Atorvastatin activates PPAR-gamma and attenuates the inflammatory response in human monocytes.
Topics: Anticholesteremic Agents; Atorvastatin; Cell Death; Cells, Cultured; Chemokine CCL2; Heptanoic Acids; Humans; Inflammation; Matrix Metalloproteinase 9; Monocytes; Oxygen Consumption; Pyrroles; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Tumor Necrosis Factor-alpha | 2002 |
[Effect of a non-steroidal anti-inflammatory agent, tolmetin sodium on exudative inflammation in experimental animals (author's transl)].
Topics: Animals; Anti-Inflammatory Agents; Capillary Permeability; Carrageenan; Cell Differentiation; Edema; Erythrocyte Membrane; Exudates and Transudates; Guinea Pigs; Hemolysis; Hot Temperature; In Vitro Techniques; Inflammation; Kaolin; Lymphocytes; Male; Mice; Protein Denaturation; Pyrroles; Rats; Sunburn; Tolmetin | 1979 |
[Clopirac effectiveness in traumatology and non articular rheumatisms (author's transl)].
Topics: Adult; Female; Humans; Inflammation; Ligaments, Articular; Male; Middle Aged; Postoperative Complications; Pyrroles; Rheumatic Diseases | 1975 |
[Clopirac in the treatment of posttraumatic inflammation (author's transl)].
Topics: Adult; Aged; Drug Evaluation; Humans; Inflammation; Male; Middle Aged; Pyrroles; Wounds and Injuries | 1975 |
Profile of activity of a new anti-inflammatory agent, ST 679 (MED 15).
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Concanavalin A; Dose-Response Relationship, Drug; Drug Administration Schedule; Edema; Female; Glycine; Inflammation; Nystatin; Pyrroles; Rats; Rats, Inbred Strains | 1990 |
[(1H-imidazol-1-yl)methyl]- and [(3-pyridinyl)methyl]pyrroles as thromboxane synthetase inhibitors.
Topics: Animals; Aorta; Biological Availability; Blood Platelets; Chemical Phenomena; Chemistry; Humans; Imidazoles; Inflammation; Kidney Diseases; Male; Mice; Microsomes; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Pyridines; Pyrroles; Rats; Structure-Activity Relationship; Swine; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase | 1989 |
Synthesis and antiinflammatory and analgesic activity of 5-aroyl-6-(methylthio)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-ca rboxyl ic acids and 1-methyl-4-(methylthio)-5-aroylpyrrole-2-acetic acids.
Topics: Acetates; Analgesia; Animals; Aspirin; Benzoquinones; Carboxylic Acids; Carrageenan; Chemical Phenomena; Chemistry; Edema; Inflammation; Mice; Molecular Structure; Pain Measurement; Phenylbutazone; Pyrroles; Quinones; Rats | 1989 |
Synthesis and antiinflammatory and analgesic activity of 5-aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids. The 6-substituted compounds.
Topics: Analgesia; Animals; Carboxylic Acids; Chemical Phenomena; Chemistry; Inflammation; Magnetic Resonance Spectroscopy; Mice; Pyrroles; Rats; Structure-Activity Relationship | 1987 |
The role of PMN-leukocyte lysosomes in tissue injury, inflammation and hypersensitivity. 8. Mode of action and properties of vascular permeability factors released by PMN-leukocytes during 'in vitro' phagocytosis.
Topics: Animals; Ascitic Fluid; Autacoids; Capillary Permeability; Chromatography; Chromatography, Gel; Cytoplasmic Granules; Electrophoresis; Female; Gels; Guinea Pigs; Histamine H1 Antagonists; Histamine Release; Ileum; Inflammation; Leukocytes; Lung; Lysosomes; Mast Cells; Membranes, Artificial; Muscle Contraction; Muscle, Smooth; Phagocytosis; Prostaglandins; Proteins; Pyrroles; Rabbits; Rats; Serotonin; Ultracentrifugation; Uterus; Wounds and Injuries | 1971 |
Suppression of inflammation and histidine decarboxylase by protein synthesis inhibitors.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Carrageenan; Cycloheximide; Dactinomycin; Endotoxins; Female; Hydrocortisone; Indomethacin; Inflammation; Mice; Polymyxins; Protein Biosynthesis; Proteins; Puromycin; Pyrroles; Rats; Turpentine | 1968 |
Cutaneous reaction to prostaglandins E 1 ,E 2 and F 2 in the bovine.
Topics: Animals; Bradykinin; Capillary Permeability; Cattle; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Inflammation; Injections, Intradermal; Mast Cells; p-Methoxy-N-methylphenethylamine; Prostaglandins; Pyrroles; Skin; Skin Diseases | 1972 |
][A new method for screening of analgesics applied to heat induced inflammatory pain].
Topics: Aminopyrine; Analgesics; Animals; Aspirin; Burns; Drug Evaluation, Preclinical; Flufenamic Acid; Habituation, Psychophysiologic; Hot Temperature; Ibuprofen; Indomethacin; Inflammation; Mefenamic Acid; Phenylbutazone; Pyrroles; Rats | 1974 |