Compounds > pyrroles
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pyrroles and Injury, Myocardial Reperfusion

pyrroles has been researched along with Injury, Myocardial Reperfusion in 65 studies

Research

Studies (65)

TimeframeStudies, this research(%)All Research%
pre-19902 (3.08)18.7374
1990's18 (27.69)18.2507
2000's25 (38.46)29.6817
2010's20 (30.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baines, CP; Domeier, TL; Hill, MA; Jones, JL; Karasseva, NG; Krenz, M; Lambert, MD; Lindman, BR; Nourian, Z; Peana, D; Veteto, AB1
Bedja, D; Biswal, S; Casin, KM; Chan, A; Fallica, J; Kohr, MJ; Mackowski, N; St Paul, A; Veenema, RJ; Zhu, G1
Hanouz, JL; Legallois, D; Lemoine, S; Manrique, A; Massetti, M; Zhu, L1
Harmann, LM; Meyer, J; Petersen, M; Routhu, KV; Sonin, DL; Strande, JL; Wakatsuki, T1
Chen, M; Li, H; Wang, Y1
Cai, A; Dong, Y; Huang, Y; Li, L; Mai, W; Qiu, R; Rao, S; Yu, D; Zheng, D; Zhou, Y1
Chaudagar, KK; Mehta, AA1
Chen, L; Chen, M; Zhou, W1
Liu, XH; Qu, Y; Shen, H; Song, DG; Xia, JG; Xu, FF1
Luo, YQ; Xu, Y; Yang, Y1
Al-Masri, AA; El Eter, EA; Lateef, R; Mohamed, OY1
Chen, L; Ding, D; Dong, Q; Du, YM; Fu, D; Guo, KF; Han, B; Li, J; Liao, YH; Qian, C; Wang, BB; Wu, QF; Zhao, N1
Buss, S; Filusch, A; Hansen, A; Hardt, S; Katus, HA; Kuecherer, HF1
Li, J; Li, X; Li, ZQ; Liu, YY; Pan, W; Sun, YM; Tian, Y; Wang, LF1
Briguori, C; Castelli, A; Chieffo, A; Colombo, A; Focaccio, A; Golia, B; Montorfano, M; Mussardo, M; Ricciardelli, B; Visconti, G1
Miao, HF; Qian, LB; Ru, XC; Wang, HP; Xu, HC; Ye, ZG1
Wang, H; Ye, P; Zhang, JY1
Drevenšek, G; Janić, M; Jerin, A; Lunder, M; Sabovič, M; Skitek, M; Ziberna, L1
Cao, Y; Fan, Y; Huang, Y; Yang, S1
Li, W; Liu, K; Ma, A; Shao, L; Wang, J; Wang, Z; Wu, D; Zhang, P; Zhang, Y1
Cao, Y; Fan, Y; Huang, Y; Yang, S; Zhang, X1
Wang, H; Ye, P; Zhang, J1
Davidson, SM; Elliot, PM; Harding, SE; Hausenloy, DJ; McGregor, C; Rees, PS; Yellon, DM1
Ashitkov, T; Ballinger, S; Birnbaum, Y; Motamedi, M; Uretsky, BF1
Jaimes, EA; Raij, L; Zhou, MS1
Di Sciascio, G; Nusca, A; Pasceri, V; Patti, G; Pristipino, C; Richichi, G1
Birnbaum, Y; Hu, ZY; Rosanio, S; Schwarz, ER; Tavackoli, S; Uretsky, BF; Ye, Y1
Efthymiou, CA; Mocanu, MM; Yellon, DM1
Atkinson, N; Brue, RJ; Harvey, M; Omiyi, D; Taormina, P; Young, LH1
Atar, S; Birnbaum, Y; Freeberg, SY; Huang, MH; Rahman, AM; Rosanio, S; Uretsky, BF; Ye, Y1
Kukreja, RC1
Birnbaum, Y; Huang, MH; Lin, Y; Lui, CY; Martinez, JD; Perez-Polo, JR; Uretsky, BF; Ye, Y1
Birnbaum, Y; Huang, MH; Hughes, MG; Lin, Y; Manickavasagam, S; McAdoo, DJ; Perez-Polo, R; Uretsky, BF; Ye, Y1
Baker, JE; Fu, X; Gross, GJ; Hsu, A; Strande, JL; Su, J1
Bose, AK; Carr, RD; Mocanu, MM; Yellon, DM1
Carnes, CA; Hideg, K; Kálai, T; Khan, M; Kuppusamy, P; Kutala, VK; Mandal, R; Mohan, IK; Sridhar, A; Varadharaj, S1
Aikawa, E; Chen, JW; Figueiredo, JL; Libby, P; Nahrendorf, M; Panizzi, P; Sosnovik, D; Swirski, FK; Weissleder, R1
Chen, MH; Liu, JH; Zhou, Y1
Birnbaum, Y; Lin, Y; Merla, R; Perez-Polo, JR; Uretsky, BF; Ye, Y1
Abu Said, GH; Birnbaum, Y; Hughes, MG; Lin, Y; Manickavasagam, S; McAdoo, DJ; Perez-Polo, RJ; Ye, Y1
Hausenloy, DJ; Riksen, NP; Yellon, DM1
Abe, T; Arita, M; Saikawa, T; Sakata, T; Sato, T; Shigematsu, S1
D'Alonzo, AJ; Darbenzio, RB; Grover, GJ; Parham, CS1
Dux, L; Ferdinandy, P; Koltai, M; Szilvássy, Z1
D'Alonzo, AJ; Darbenzio, RB; Grover, GJ; Hess, TA; Sewter, JC; Sleph, PG1
Moore, TL; Shebuski, RJ; Toombs, CF1
Armstrong, JM; Bellemin-Baurreau, J; Hicks, PE; Poizot, A; Rochette, L1
Das, DK; Engelman, RM; Szerdahelyi, P; Tosaki, A1
Hellegouarch, A; Tosaki, A1
Nakaya, H1
Droy-Lefaix, MT; Ferdinandy, P; Koltai, M; Szilvássy, Z; Tarrade, T1
Dzwonczyk, S; Grover, GJ; Monticello, TM1
Das, DK; Engelman, RM; Tosaki, A1
Katoh, I; Kitagawa, T; Masuda, Y; Shimoe, Y; Yoshizumi, M1
Baczkó, I; Leprán, I; Papp, JG1
Ichihara, K; Satoh, K1
Beier, N; Gross, GJ; Gumina, RJ; Schelling, P1
Hideg, K; Kalai, T; Kuppusamy, P; Li, H; Xu, KY; Zhou, L; Zweier, JL1
Matsui, K; Ohashi, N; Sasabe, M; Yamamoto, S1
Becker, BF; Gerlach, E; Leipert, B; Raschke, P; Reinholz, N1
Linz, W; Martorana, PA; Schölkens, BA1
Linz, W; Schölkens, BA1
Dzwonczyk, S; Grover, GJ; Parham, CS; Sleph, PG1
Chen, X; Deng, HW; Li, DY; Li, YJ; Pi, XJ1
Albus, U; Linz, W; Schölkens, BA1

Reviews

1 review(s) available for pyrroles and Injury, Myocardial Reperfusion

ArticleYear
[Potential role of ATP-sensitive K+ channels in ischemia- and reperfusion-induced arrhythmias].
    Kokyu to junkan. Respiration & circulation, 1993, Volume: 41, Issue:6

    Topics: Action Potentials; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Benzopyrans; Cromakalim; Glyburide; Guanidines; Humans; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Niacinamide; Nicorandil; Pinacidil; Potassium; Potassium Channels; Pyrroles; Tolbutamide

1993

Trials

3 trial(s) available for pyrroles and Injury, Myocardial Reperfusion

ArticleYear
Protection by atorvastatin pretreatment in patients undergoing primary percutaneous coronary intervention is associated with the lower levels of oxygen free radicals.
    Journal of cardiovascular pharmacology, 2013, Volume: 62, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Atorvastatin; Biomarkers; Cardiotonic Agents; China; Double-Blind Method; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion Injury; Percutaneous Coronary Intervention; Premedication; Pyrroles; Reactive Oxygen Species; Severity of Illness Index

2013
Novel approaches for preventing or limiting events (Naples) II trial: impact of a single high loading dose of atorvastatin on periprocedural myocardial infarction.
    Journal of the American College of Cardiology, 2009, Dec-01, Volume: 54, Issue:23

    Topics: Aged; Angioplasty, Balloon, Coronary; Atorvastatin; Dose-Response Relationship, Drug; Electrocardiography; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion Injury; Pyrroles; Treatment Outcome

2009
Randomized trial of atorvastatin for reduction of myocardial damage during coronary intervention: results from the ARMYDA (Atorvastatin for Reduction of MYocardial Damage during Angioplasty) study.
    Circulation, 2004, Aug-10, Volume: 110, Issue:6

    Topics: Aged; Angina Pectoris; Angioplasty, Balloon, Coronary; Anticoagulants; Atorvastatin; Biomarkers; Coronary Stenosis; Creatine Kinase; Creatine Kinase, MB Form; Double-Blind Method; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isoenzymes; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion Injury; Myoglobin; Premedication; Prospective Studies; Pyrroles; Stents; Treatment Outcome; Troponin I

2004

Other Studies

61 other study(ies) available for pyrroles and Injury, Myocardial Reperfusion

ArticleYear
TRPV4 increases cardiomyocyte calcium cycling and contractility yet contributes to damage in the aged heart following hypoosmotic stress.
    Cardiovascular research, 2019, 01-01, Volume: 115, Issue:1

    Topics: Age Factors; Animals; Calcium; Calcium Signaling; Disease Models, Animal; Humans; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Osmotic Pressure; Pyrroles; Sarcoplasmic Reticulum; TRPV Cation Channels

2019
S-Nitrosoglutathione Reductase Is Essential for Protecting the Female Heart From Ischemia-Reperfusion Injury.
    Circulation research, 2018, 11-09, Volume: 123, Issue:11

    Topics: Alcohol Dehydrogenase; Animals; Benzamides; Cardiotonic Agents; Enzyme Inhibitors; Female; Heart; Male; Mice; Mice, Inbred C57BL; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Pyrroles; Sex Factors

2018
Atorvastatin-induced cardioprotection of human myocardium is mediated by the inhibition of mitochondrial permeability transition pore opening via tumor necrosis factor-α and Janus kinase/signal transducers and activators of transcription pathway.
    Anesthesiology, 2013, Volume: 118, Issue:6

    Topics: Aged; Atorvastatin; Blotting, Western; Cardiotonic Agents; Dose-Response Relationship, Drug; Female; Heptanoic Acids; Humans; Janus Kinases; Male; Middle Aged; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Reperfusion Injury; Myocardium; Pyrroles; Signal Transduction; Tumor Necrosis Factor-alpha

2013
Protease-activated receptor 1 inhibition by SCH79797 attenuates left ventricular remodeling and profibrotic activities of cardiac fibroblasts.
    Journal of cardiovascular pharmacology and therapeutics, 2013, Volume: 18, Issue:5

    Topics: Animals; Disease Models, Animal; Fibroblasts; Fibrosis; Imaging, Three-Dimensional; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardial Infarction; Myocardial Reperfusion Injury; Phosphorylation; Pyrroles; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor, PAR-1; Transforming Growth Factor beta; Ventricular Remodeling

2013
Atorvastatin treatment of rats with ischemia-reperfusion injury improves adipose-derived mesenchymal stem cell migration and survival via the SDF-1α/CXCR-4 axis.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Adipose Tissue; Allografts; Animals; Atorvastatin; Cell Movement; Cell Survival; Chemokine CXCL12; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Myocardial Reperfusion Injury; Myocytes, Cardiac; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, CXCR4

2013
Effect of atorvastatin on the angiogenic responsiveness of coronary endothelial cells in normal and streptozotocin (STZ) induced diabetic rats.
    Canadian journal of physiology and pharmacology, 2014, Volume: 92, Issue:4

    Topics: Androstadienes; Animals; Anticholesteremic Agents; Atorvastatin; Benzophenanthridines; Chick Embryo; Chorioallantoic Membrane; Coronary Vessels; Diabetes Mellitus, Experimental; Endothelial Cells; Enzyme Inhibitors; Heptanoic Acids; Male; Myocardial Reperfusion Injury; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pyrroles; Rats; Rats, Wistar; Streptozocin; Vascular Endothelial Growth Factor A; Wortmannin

2014
[Atorvastatin inhibits cardiomyocyte apoptosis via down-cegulation the expression mitofusin 2 after myocardial ischemia/reperfusion injury in rats].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2014, Volume: 30, Issue:4

    Topics: Animals; Apoptosis; Atorvastatin; Down-Regulation; GTP Phosphohydrolases; Heptanoic Acids; Male; Membrane Proteins; Mitochondrial Proteins; Myocardial Reperfusion Injury; Myocytes, Cardiac; Phosphoproteins; Protein Transport; Proto-Oncogene Proteins c-akt; Pyrroles; Rats; Rats, Sprague-Dawley

2014
Atorvastatin post-conditioning attenuates myocardial ischemia reperfusion injury via inhibiting endoplasmic reticulum stress-related apoptosis.
    Shock (Augusta, Ga.), 2014, Volume: 42, Issue:4

    Topics: Animals; Apoptosis; Atorvastatin; Endoplasmic Reticulum Stress; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemic Postconditioning; Male; Myocardial Reperfusion Injury; Pyrroles; Rats; Rats, Sprague-Dawley

2014
Effect of atorvastatin on serum oxidative stress and N-terminal brain natriuretic peptide expression in rats.
    Asian Pacific journal of tropical medicine, 2014, Volume: 7, Issue:5

    Topics: Animals; Atorvastatin; Heptanoic Acids; Male; Myocardial Reperfusion Injury; Natriuretic Peptide, Brain; Oxidative Stress; Peptide Fragments; Pyrroles; Rats; Rats, Sprague-Dawley

2014
SCH 79797, a selective PAR1 antagonist, protects against ischemia/reperfusion-induced arrhythmias in the rat hearts.
    European review for medical and pharmacological sciences, 2016, Volume: 20, Issue:22

    Topics: Animals; Arrhythmias, Cardiac; Disease Models, Animal; Male; Myocardial Reperfusion Injury; Pyrroles; Quinazolines; Rats; Rats, Wistar; Receptor, PAR-1

2016
Blockage of transient receptor potential vanilloid 4 alleviates myocardial ischemia/reperfusion injury in mice.
    Scientific reports, 2017, 02-16, Volume: 7

    Topics: Animals; Apoptosis; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression; Gene Knockout Techniques; Glycogen Synthase Kinase 3 beta; Heart Function Tests; Mice; Molecular Targeted Therapy; Morpholines; Myocardial Reperfusion Injury; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrroles; Signal Transduction; TRPV Cation Channels

2017
Evaluation cardioprotective effects of atorvastatin in rats by real time myocardial contrast echocardiography.
    Echocardiography (Mount Kisco, N.Y.), 2008, Volume: 25, Issue:9

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; Cardiotonic Agents; Computer Systems; Contrast Media; Echocardiography; Heptanoic Acids; Image Enhancement; Male; Myocardial Reperfusion Injury; Pyrroles; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Treatment Outcome; Ventricular Dysfunction, Left

2008
Effect of atorvastatin on expression of IL-10 and TNF-alpha mRNA in myocardial ischemia-reperfusion injury in rats.
    Biochemical and biophysical research communications, 2009, May-01, Volume: 382, Issue:2

    Topics: Animals; Atorvastatin; Heart Ventricles; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-10; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Pyrroles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tumor Necrosis Factor-alpha; Ventricular Function

2009
[Electrophysiological effect of atorvastatin on isolated rat hearts injured by ischemia/reperfusion].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2010, Volume: 39, Issue:6

    Topics: Animals; Atorvastatin; Electrophysiological Phenomena; Heart; Heptanoic Acids; In Vitro Techniques; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Pyrroles; Rats; Rats, Sprague-Dawley

2010
[Protective effect of atrovastatin against myocardial ischemia-reperfusion injury and on liver and kidney functions in aged rats].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2012, Volume: 32, Issue:3

    Topics: Aging; Animals; Atorvastatin; Female; Heptanoic Acids; Kidney; Liver; Male; Multiple Organ Failure; Myocardial Ischemia; Myocardial Reperfusion Injury; Pyrroles; Rats; Rats, Wistar

2012
Low-dose atorvastatin, losartan, and particularly their combination, provide cardiovascular protection in isolated rat heart and aorta.
    Heart and vessels, 2013, Volume: 28, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Atorvastatin; Biomarkers; Blood Pressure; Coronary Circulation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Heart; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Losartan; Male; Myocardial Reperfusion Injury; Perfusion; Pyrroles; Rats; Rats, Wistar; Time Factors; Vasodilation; Vasodilator Agents

2013
Effects of acute and chronic atorvastatin on cardioprotection of ischemic postconditioning in isolated rat hearts.
    Cardiovascular therapeutics, 2013, Volume: 31, Issue:4

    Topics: Animals; Atorvastatin; Cardiotonic Agents; Drug Administration Schedule; Hemodynamics; Heptanoic Acids; In Vitro Techniques; Ischemic Postconditioning; Male; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide Synthase Type III; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrroles; Rats; Rats, Wistar; Signal Transduction; Time Factors

2013
Atorvastatin preconditioning improves the forward blood flow in the no-reflow rats.
    Fundamental & clinical pharmacology, 2014, Volume: 28, Issue:1

    Topics: Animals; Atorvastatin; Echocardiography; Fibrinogen; Fibrosis; Hemodynamics; Heptanoic Acids; Inflammation; Male; Microcirculation; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Pyrroles; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Tumor Necrosis Factor-alpha

2014
Comparison of cardioprotective efficacy resulting from a combination of atorvastatin and ischaemic post-conditioning in diabetic and non-diabetic rats.
    Clinical and experimental pharmacology & physiology, 2012, Volume: 39, Issue:11

    Topics: Animals; Atorvastatin; Cardiotonic Agents; Diabetes Mellitus, Experimental; Heart; Hemodynamics; Heptanoic Acids; Ischemic Postconditioning; Male; Myocardial Reperfusion Injury; Nitric Oxide Synthase Type III; Proto-Oncogene Proteins c-akt; Pyrroles; Rats; Rats, Wistar; Signal Transduction

2012
[Effect of atorvastatin on eNOS synthesis in organs of aging rats with myocardial ischemia-reperfusion].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2012, Volume: 32, Issue:12

    Topics: Animals; Atorvastatin; Female; Heptanoic Acids; Kidney; Liver; Male; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide Synthase Type III; Pyrroles; Rats; Rats, Wistar

2012
The mitochondrial permeability transition pore as a target for cardioprotection in hypertrophic cardiomyopathy.
    Cardiovascular drugs and therapy, 2013, Volume: 27, Issue:3

    Topics: Atorvastatin; Cardiomyopathy, Hypertrophic; Cardiotonic Agents; Cells, Cultured; Cyclosporine; Heptanoic Acids; Humans; Ion Channel Gating; Membrane Potential, Mitochondrial; Microscopy, Confocal; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Reperfusion Injury; Myocytes, Cardiac; Pyrroles; Time Factors

2013
Reduction of infarct size by short-term pretreatment with atorvastatin.
    Cardiovascular drugs and therapy, 2003, Volume: 17, Issue:1

    Topics: Animals; Atorvastatin; Dose-Response Relationship, Drug; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Pyrroles; Rats; Rats, Sprague-Dawley

2003
Atorvastatin prevents end-organ injury in salt-sensitive hypertension: role of eNOS and oxidant stress.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 44, Issue:2

    Topics: Animals; Aorta; Atorvastatin; Down-Regulation; Endothelium, Vascular; Heart Ventricles; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Organ Size; Oxidative Stress; Pyrroles; Rats; Rats, Sprague-Dawley; Sodium, Dietary

2004
Prostaglandins mediate the cardioprotective effects of atorvastatin against ischemia-reperfusion injury.
    Cardiovascular research, 2005, Feb-01, Volume: 65, Issue:2

    Topics: Animals; Atorvastatin; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Intramolecular Oxidoreductases; Isoxazoles; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phospholipases A; Phospholipases A2; Phosphorylation; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrroles; Random Allocation; Rats; Rats, Sprague-Dawley; Sulfonamides

2005
Atorvastatin and myocardial reperfusion injury: new pleiotropic effect implicating multiple prosurvival signaling.
    Journal of cardiovascular pharmacology, 2005, Volume: 45, Issue:3

    Topics: Animals; Atorvastatin; Blotting, Western; Cell Survival; Densitometry; Heat-Shock Proteins; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Myocardial Reperfusion Injury; Myocardium; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrroles; Signal Transduction

2005
Protein kinase C betaII peptide inhibitor exerts cardioprotective effects in rat cardiac ischemia/reperfusion injury.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:2

    Topics: Animals; Aorta, Thoracic; Blood Pressure; Cardiotonic Agents; Cell Adhesion; Enzyme Inhibitors; In Vitro Techniques; Isoenzymes; Male; Mesylates; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Protein Kinase C; Protein Kinase C beta; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors for Activated C Kinase; Receptors, Cell Surface; Superoxides; Ventricular Function, Left

2005
Enhanced cardioprotection against ischemia-reperfusion injury with combining sildenafil with low-dose atorvastatin.
    Cardiovascular drugs and therapy, 2006, Volume: 20, Issue:1

    Topics: Amidines; Animals; Atorvastatin; Benzylamines; Cardiotonic Agents; Drug Synergism; Heart; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phosphodiesterase Inhibitors; Phosphorylation; Piperazines; Purines; Pyrroles; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Sulfones; Up-Regulation

2006
Synergistic effects of atorvastatin and sildenafil in cardioprotection--role of NO.
    Cardiovascular drugs and therapy, 2006, Volume: 20, Issue:1

    Topics: Animals; Atorvastatin; Cardiotonic Agents; Drug Synergism; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myocardial Reperfusion Injury; Nitric Oxide; Phosphodiesterase Inhibitors; Piperazines; Purines; Pyrroles; Sildenafil Citrate; Sulfones

2006
Aspirin before reperfusion blunts the infarct size limiting effect of atorvastatin.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 292, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Atorvastatin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Membrane Proteins; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Pyrroles; Rats; Rats, Sprague-Dawley

2007
Enhanced cardioprotection against ischemia-reperfusion injury with a dipyridamole and low-dose atorvastatin combination.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:1

    Topics: Adenosine; Administration, Oral; Animals; Atorvastatin; Cardiotonic Agents; Dipyridamole; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Heptanoic Acids; Male; Myocardial Reperfusion Injury; Pyrroles; Rats; Rats, Sprague-Dawley; Treatment Outcome

2007
SCH 79797, a selective PAR1 antagonist, limits myocardial ischemia/reperfusion injury in rat hearts.
    Basic research in cardiology, 2007, Volume: 102, Issue:4

    Topics: Androstadienes; Animals; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyburide; Hirudins; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Oligopeptides; omega-N-Methylarginine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Potassium Channel Blockers; Potassium Channels; Proto-Oncogene Proteins c-akt; Pyrroles; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor, PAR-1; Recombinant Proteins; Research Design; RNA, Messenger; Signal Transduction; Thrombin; Time Factors; Ventricular Function, Left; Wortmannin

2007
Myocardial ischaemia-reperfusion injury is attenuated by intact glucagon like peptide-1 (GLP-1) in the in vitro rat heart and may involve the p70s6K pathway.
    Cardiovascular drugs and therapy, 2007, Volume: 21, Issue:4

    Topics: Animals; Blotting, Western; Disease Models, Animal; Enzyme Inhibitors; Glucagon-Like Peptide 1; In Vitro Techniques; Incretins; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Phosphatidylinositol 3-Kinases; Protein Kinases; Pyrroles; Random Allocation; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; Time Factors; TOR Serine-Threonine Kinases; Valine

2007
N-hydroxy-pyrroline modification of verapamil exhibits antioxidant protection of the heart against ischemia/reperfusion-induced cardiac dysfunction without compromising its calcium antagonistic activity.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 323, Issue:1

    Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels; Free Radical Scavengers; In Vitro Techniques; Male; Molecular Structure; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Patch-Clamp Techniques; Pyrroles; Rats; Rats, Sprague-Dawley; Superoxides; Verapamil

2007
Activatable magnetic resonance imaging agent reports myeloperoxidase activity in healing infarcts and noninvasively detects the antiinflammatory effects of atorvastatin on ischemia-reperfusion injury.
    Circulation, 2008, Mar-04, Volume: 117, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Atorvastatin; Gadolinium; Heptanoic Acids; Magnetic Resonance Imaging; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardial Reperfusion Injury; Peroxidase; Pyrroles

2008
[Cardioprotective effects of atorvastatin preconditioning via iNOS upregulation in a rabbit ischemia/reperfusion model].
    Zhonghua xin xue guan bing za zhi, 2007, Volume: 35, Issue:11

    Topics: Animals; Atorvastatin; Disease Models, Animal; Heptanoic Acids; Ischemic Preconditioning, Myocardial; Male; Myocardial Reperfusion Injury; Nitric Oxide Synthase Type II; Potassium Channels; Pyrroles; Rabbits; Up-Regulation

2007
Pretreatment with high-dose statin, but not low-dose statin, ezetimibe, or the combination of low-dose statin and ezetimibe, limits infarct size in the rat.
    Journal of cardiovascular pharmacology and therapeutics, 2008, Volume: 13, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anticholesteremic Agents; Atorvastatin; Azetidines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ezetimibe; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Nitric Oxide Synthase; Pyrroles; Rats; Rats, Sprague-Dawley; Simvastatin; Up-Regulation

2008
Caffeinated coffee blunts the myocardial protective effects of statins against ischemia-reperfusion injury in the rat.
    Cardiovascular drugs and therapy, 2008, Volume: 22, Issue:4

    Topics: Administration, Oral; Animals; Atorvastatin; Blood Pressure; Caffeine; Coffee; Disease Models, Animal; Food-Drug Interactions; Heart Rate; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1

2008
Wake up and smell the coffee: yet another no go for cardiac patients? : editorial to "caffeinated coffee blunts the myocardial protective effects of statins against ischemia-reperfusion injury in the rat" by Ye et al.
    Cardiovascular drugs and therapy, 2008, Volume: 22, Issue:4

    Topics: Administration, Oral; Animals; Atorvastatin; Caffeine; Coffee; Food-Drug Interactions; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Pyrroles; Rats

2008
Pharmacological evidence for the persistent activation of ATP-sensitive K+ channels in early phase of reperfusion and its protective role against myocardial stunning.
    Circulation, 1995, Oct-15, Volume: 92, Issue:8

    Topics: Action Potentials; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Benzopyrans; Cromakalim; Glyburide; Guinea Pigs; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardial Stunning; Myocardium; Perfusion; Potassium Channels; Pyrroles

1995
Cardioprotection with the KATP opener cromakalim is not correlated with ischemic myocardial action potential duration.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:1

    Topics: Action Potentials; Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Benzopyrans; Cromakalim; Dogs; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Infusions, Intravenous; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Phenethylamines; Potassium Channels; Pyrroles; Regional Blood Flow; Sulfonamides

1995
Ventricular overdrive pacing-induced preconditioning and no-flow ischemia-induced preconditioning in isolated working rat hearts.
    Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:1

    Topics: Animals; Benzopyrans; Blood Pressure; Cardiac Pacing, Artificial; Coronary Circulation; Cromakalim; Disease Models, Animal; Glyburide; Heart; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Potassium Channels; Pyrroles; Rats; Rats, Wistar; Vasodilator Agents

1995
Effect of potassium on the action of the KATP modulators cromakalim, pinacidil, or glibenclamide on arrhythmias in isolated perfused rat heart subjected to regional ischaemia.
    Cardiovascular research, 1994, Volume: 28, Issue:6

    Topics: Animals; Arrhythmias, Cardiac; Benzopyrans; Cromakalim; Glyburide; Guanidines; Heart; Heart Rate; Myocardial Ischemia; Myocardial Reperfusion Injury; Perfusion; Pinacidil; Potassium; Pyrroles; Rats; Rats, Sprague-Dawley; Vasodilator Agents

1994
Cardioprotection with U-89232 is not reversible with glibenclamide: evidence of a novel anti-ischemic agent derived from cromakalim.
    Pharmacology, 1994, Volume: 49, Issue:2

    Topics: Animals; Benzopyrans; Cromakalim; Female; Glyburide; Guanidines; Heart; Hemodynamics; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Necrosis; Potassium Channels; Pyrroles; Rabbits; Vasodilator Agents

1994
Effects of ATP-dependent K+ channel modulators on an ischemia-reperfusion rabbit isolated heart model with programmed electrical stimulation.
    European journal of pharmacology, 1994, Apr-21, Volume: 256, Issue:2

    Topics: Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Benzopyrans; Blood Pressure; Coronary Circulation; Cromakalim; Electric Stimulation; Glyburide; Heart; In Vitro Techniques; Myocardial Ischemia; Myocardial Reperfusion Injury; Potassium Channels; Pyrroles; Rabbits; Refractory Period, Electrophysiological; Vasodilator Agents

1994
Potassium channel openers and blockers: do they possess proarrhythmic or antiarrhythmic activity in ischemic and reperfused rat hearts?
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Benzopyrans; Cations; Cromakalim; Glyburide; Heart; Ion Channel Gating; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Potassium Channels; Pyrroles; Rats; Rats, Sprague-Dawley

1993
Adenosine triphosphate-sensitive potassium channel blocking agent ameliorates, but the opening agent aggravates, ischemia/reperfusion-induced injury. Heart function studies in nonfibrillating isolated hearts.
    Journal of the American College of Cardiology, 1994, Volume: 23, Issue:2

    Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzopyrans; Cromakalim; Dose-Response Relationship, Drug; Glyburide; Guinea Pigs; Magnetic Resonance Spectroscopy; Male; Myocardial Reperfusion Injury; Myocardium; Potassium Channels; Pyrroles; Tachycardia, Ventricular; Ventricular Fibrillation

1994
KATP channel modulation in working rat hearts with coronary occlusion: effects of cromakalim, cicletanine, and glibenclamide.
    Cardiovascular research, 1995, Volume: 30, Issue:5

    Topics: Animals; Anti-Arrhythmia Agents; Benzopyrans; Coronary Circulation; Coronary Disease; Cromakalim; Glyburide; Heart; Ion Channel Gating; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Potassium Channels; Pyridines; Pyrroles; Rats; Rats, Wistar; Ventricular Fibrillation

1995
Comparative cardioprotective effects of cromakalim and diltiazem in ischemic hypertrophied rat hearts.
    The American journal of physiology, 1996, Volume: 270, Issue:1 Pt 2

    Topics: Animals; Benzopyrans; Blood Pressure; Cardiomegaly; Cromakalim; Diltiazem; Heart; Heart Rate; L-Lactate Dehydrogenase; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Pyrroles; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Ventricular Function, Left

1996
Effects of cromakalim and glibenclamide in ischemic and reperfused hearts.
    Annals of the New York Academy of Sciences, 1996, Sep-30, Volume: 793

    Topics: Animals; Anti-Arrhythmia Agents; Benzopyrans; Cromakalim; Diabetes Mellitus, Experimental; Glyburide; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Pyrroles; Rats; Rats, Sprague-Dawley

1996
Effect of cromakalim on ischemic and reperfused immature heart: experiments with isolated neonatal New Zealand white rabbit hearts.
    The Tokushima journal of experimental medicine, 1996, Volume: 43, Issue:3-4

    Topics: Animals; Animals, Newborn; Benzopyrans; Cromakalim; In Vitro Techniques; Myocardial Contraction; Myocardial Reperfusion Injury; Potassium; Potassium Channels; Pyrroles; Rabbits; Sodium

1996
KATP channel modulators increase survival rate during coronary occlusion-reperfusion in anaesthetized rats.
    European journal of pharmacology, 1997, Apr-11, Volume: 324, Issue:1

    Topics: Action Potentials; Adenosine Triphosphate; Analysis of Variance; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzopyrans; Blood Pressure; Calcium Channel Blockers; Coronary Disease; Cromakalim; Disease Models, Animal; Dose-Response Relationship, Drug; Electrocardiography; Glyburide; Guanidines; Heart Rate; Male; Myocardial Reperfusion Injury; Pinacidil; Potassium Channels; Pyrroles; Rats; Rats, Sprague-Dawley; Survival Rate; Vasodilator Agents; Ventricular Fibrillation

1997
Lipophilic HMG-CoA reductase inhibitors increase myocardial stunning in dogs.
    Journal of cardiovascular pharmacology, 2000, Volume: 35, Issue:2

    Topics: Adenosine Triphosphate; Animals; Atorvastatin; Cholesterol; Dogs; Fatty Acids, Monounsaturated; Female; Fluvastatin; Hemodynamics; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Myocardial Reperfusion Injury; Myocardial Stunning; Perfusion; Pyridines; Pyrroles; Random Allocation; Simvastatin; Solubility; Time Factors

2000
Inhibitors of ischemic preconditioning do not attenuate Na+/H+ exchange inhibitor mediated cardioprotection.
    Journal of cardiovascular pharmacology, 2000, Volume: 35, Issue:6

    Topics: Animals; Benzamides; Dogs; Female; Glyburide; Hemodynamics; Hypoglycemic Agents; Ischemic Preconditioning; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Purines; Pyrroles; Sodium-Hydrogen Exchangers; Sulfonamides

2000
A pyrroline derivative of mexiletine offers marked protection against ischemia/reperfusion-induced myocardial contractile dysfunction.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Antioxidants; Binding, Competitive; Coronary Circulation; Dose-Response Relationship, Drug; Female; Hydroxyl Radical; Mexiletine; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Ouabain; Oxidation-Reduction; Pyrroles; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Ventricular Dysfunction, Left; Ventricular Pressure

2000
Effect of an orally active Na+/H+ exchange inhibitor, SMP-300, on experimental angina and myocardial infarction models in rats.
    Journal of cardiovascular pharmacology, 2002, Volume: 39, Issue:2

    Topics: Administration, Oral; Angina Pectoris; Animals; Azocines; Coronary Disease; Electrocardiography; Isoproterenol; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nicorandil; Nifedipine; Propranolol; Pyrroles; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sodium-Hydrogen Exchangers; Vasodilator Agents; Vasopressins

2002
[Are the radical scavenging properties of ACE inhibitors with sulfhydryl groups in therapeutically effective concentrations of quantitative significance?].
    Klinische Wochenschrift, 1991, Volume: 69 Suppl 24

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bridged Bicyclo Compounds; Captopril; Coronary Disease; Dose-Response Relationship, Drug; Enalapril; Guinea Pigs; Hemodynamics; Hydroxides; Hydroxyl Radical; Luminescent Measurements; Myocardial Reperfusion Injury; Pyrroles; Ramipril; Sulfhydryl Reagents; Uric Acid

1991
Local inhibition of bradykinin degradation in ischemic hearts.
    Journal of cardiovascular pharmacology, 1990, Volume: 15 Suppl 6

    Topics: Anesthesia; Angiotensin-Converting Enzyme Inhibitors; Animals; Arrhythmias, Cardiac; Bradykinin; Coronary Circulation; Coronary Disease; Dogs; Female; Hemodynamics; In Vitro Techniques; L-Lactate Dehydrogenase; Lactates; Male; Myocardial Reperfusion Injury; Myocardium; Pyrroles; Ramipril; Rats; Rats, Inbred Strains; Saralasin

1990
[ACE inhibition: mechanisms of "cardioprotection" in acute myocardial ischemia].
    Klinische Wochenschrift, 1991, Volume: 69 Suppl 24

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Coronary Disease; Dogs; Dose-Response Relationship, Drug; Energy Metabolism; Hemodynamics; Myocardial Reperfusion Injury; Myocardium; Organ Culture Techniques; Pyrroles; Ramipril; Rats; Ventricular Fibrillation

1991
The protective effects of cromakalim and pinacidil on reperfusion function and infarct size in isolated perfused rat hearts and anesthetized dogs.
    Cardiovascular drugs and therapy, 1990, Volume: 4, Issue:2

    Topics: Animals; Benzopyrans; Blood Pressure; Cromakalim; Dogs; Female; Guanidines; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Pentobarbital; Pinacidil; Pyrroles; Rats; Rats, Inbred Strains; Vasodilator Agents

1990
Prostacyclin-mediated cardioprotection of captopril and ramiprilate against lipid peroxidation in rat.
    Progress in clinical and biological research, 1989, Volume: 301

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cells, Cultured; Epoprostenol; Free Radicals; In Vitro Techniques; Lipid Peroxidation; Myocardial Reperfusion Injury; Oxygen; Pyrroles; Ramipril; Rats; Rats, Inbred Strains

1989
Effects of endothelin on isolated ischaemic rat hearts during ramiprilat, bradykinin and indomethacin perfusion.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1989, Volume: 7, Issue:6

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Drug Evaluation, Preclinical; Drug Interactions; Drug Therapy, Combination; Endothelins; Endothelium, Vascular; Female; In Vitro Techniques; Indomethacin; Male; Myocardial Reperfusion; Myocardial Reperfusion Injury; Peptides; Pyrroles; Ramipril; Rats; Rats, Inbred Strains; Vasoconstrictor Agents

1989