Page last updated: 2024-08-18

pyrroles and Infarction, Middle Cerebral Artery

pyrroles has been researched along with Infarction, Middle Cerebral Artery in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (23.08)29.6817
2010's19 (73.08)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Bao, Z; Chao, H; Chen, B; He, J; Hu, J; Ji, J; Li, C; Liu, N; Miao, Z; Sun, G; Xu, L; Ye, Y; You, Y; Zhao, L; Zhao, P1
Dhammu, TS; Khan, M; Kumar, P; Qiao, F; Singh, AK; Singh, I1
Chen, Q; Guan, F; Li, M; Wang, J; Wang, W; Wang, Y; Wang, Z; Zhang, W1
Al-Fakhri, N; Dönges, S; Gassmann, M; Gerriets, T; Hörmann, M; Kinscherf, R; Mey, L; Reuter, P; Schleicher, N1
Deng, J; He, J; Hu, Z; Lei, Q; Liu, J; Lu, W; Song, T; Tao, X; Zhang, J; Zheng, L1
Chen, L; Du, Y; Hong, Z; Jie, P; Li, L; Li, Y; Lu, Z; Zhou, L; Zhou, R; Zhou, Y1
Ago, T; Arimura, K; Kamouchi, M; Kitazono, T; Kuroda, J; Makihara, N; Matsuo, R; Nakamura, K; Nishimura, A; Sugimori, H; Tachibana, M; Wakisaka, Y1
Deng, JG; Liu, J; Song, T; Tao, X1
Bonnet, C; Sibon, I1
Chen, L; Du, Y; Hong, Z; Jie, P; Li, Y; Lin, L; Tian, Y; Zhou, L1
Ago, T; Arimura, K; Kamouchi, M; Kitazono, T; Kuroda, J; Makihara, N; Nakamura, K; Nishimura, A; Ooboshi, H; Tachibana, M; Wakisaka, Y; Yoshikawa, Y1
Chen, Q; Deng, G; Li, M; Li, Q; Wan, J; Wang, J; Wang, W; Wang, Y; Yang, Q1
Freeling, JL; Lü, L; Martin, DS; Min, JW; Wang, H1
Chen, TY; Kuo, YL; Lin, WC; Tan, TY1
Derugin, N; Ferriero, DM; Shimotake, J; Vexler, ZS; Wendland, M1
Cui, L; Du, W; Li, M; Liu, L; Wang, L; Yang, R; Zhang, X1
Cardona-Gómez, GP; Céspedes-Rubio, A; Jurado, FW1
Abe, K; Deguchi, K; Deguchi, S; Ikeda, Y; Liu, N; Liu, W; Matsuura, T; Ohta, Y; Shang, J; Tian, F; Yamashita, T; Zhang, X1
Binning, MJ; Darkhabani, Z; Levy, EI; Mokin, M; Siddiqui, AH1
Du, Y; Ji, H; Li, L; Li, S; Liu, H; Zhang, X1
Chen, B; Cheng, Q; Friedman, B; Lei, IF; Lyden, PD; Olson, ES; Pereira, B; Tsien, RY; Whitney, MA; Winkle, JA; Zhao, L1
Abe, K; Deguchi, K; Hayashi, T; Nagano, I; Nagotani, S; Sato, K; Shoji, M; Zhang, W1
Appel, K; Fiebich, BL; Hüll, M; Kauppinen, RA; Kettunen, M; Koistinaho, J; Yrjänheikki, J1
Chen, J; Chopp, M; Ding, J; Kapke, A; Li, A; Lu, M; Roberts, C; Zacharek, A; Zhang, C1
Chopp, M; Hozeska-Solgot, A; Liu, XS; Zhang, L; Zhang, ZG1
Böhm, M; Dirnagl, U; Endres, M; Gertz, K; Huang, P; Laufs, U; Nickenig, G1

Other Studies

26 other study(ies) available for pyrroles and Infarction, Middle Cerebral Artery

ArticleYear
Nuclear receptor coactivator 4-mediated ferritinophagy contributes to cerebral ischemia-induced ferroptosis in ischemic stroke.
    Pharmacological research, 2021, Volume: 174

    Topics: Animals; Brain; Cells, Cultured; Ferroptosis; Glutathione; Glutathione Peroxidase; Infarction, Middle Cerebral Artery; Ischemic Stroke; Lipid Peroxidation; Male; Malondialdehyde; Mice, Inbred C57BL; Neurons; Nuclear Receptor Coactivators; Pyrroles; Pyrrolidines; Reperfusion Injury; Ubiquitin Thiolesterase

2021
S-Nitrosoglutathione Mimics the Beneficial Activity of Endothelial Nitric Oxide Synthase-Derived Nitric Oxide in a Mouse Model of Stroke.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2019, Volume: 28, Issue:12

    Topics: Alcohol Dehydrogenase; Animals; Behavior, Animal; Benzamides; Brain; Brain Edema; Disease Models, Animal; Enzyme Inhibitors; Infarction, Middle Cerebral Artery; Male; Mice, Inbred C57BL; Mice, Knockout; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type III; Pyrroles; S-Nitrosoglutathione

2019
GSK-3β as a target for protection against transient cerebral ischemia.
    International journal of medical sciences, 2017, Volume: 14, Issue:4

    Topics: Animals; beta Catenin; Blood-Brain Barrier; Brain; Disease Models, Animal; Gene Expression Regulation; Glycogen Synthase Kinase 3 beta; Humans; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Pyrimidines; Pyrroles; Rats; Stroke; Wnt Signaling Pathway; Zonula Occludens-1 Protein

2017
Neuropilin-1 modulates vascular endothelial growth factor-induced poly(ADP-ribose)-polymerase leading to reduced cerebrovascular apoptosis.
    Neurobiology of disease, 2013, Volume: 59

    Topics: Animals; Apoptosis; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Gene Expression Regulation; Humans; Indoles; Infarction, Middle Cerebral Artery; Male; Neurons; Neuropilin-1; Poly(ADP-ribose) Polymerases; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Wistar; Signal Transduction; Time Factors; Umbilical Veins; Vascular Endothelial Growth Factor A

2013
HspB8 expression in brain tissue after cerebral ischemic reperfusion and atorvastatin intervention in Sprague-Dawley rats.
    Neurological research, 2015, Volume: 37, Issue:3

    Topics: Animals; Apoptosis; Atorvastatin; Blotting, Western; Brain Ischemia; Cerebral Cortex; Disease Models, Animal; Heat-Shock Proteins; Heptanoic Acids; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Male; Neurons; Neuroprotective Agents; Pyrroles; Random Allocation; Rats, Sprague-Dawley; Reperfusion Injury; Severity of Illness Index; Tetrazolium Salts

2015
Activation of Transient Receptor Potential Vanilloid 4 is Involved in Neuronal Injury in Middle Cerebral Artery Occlusion in Mice.
    Molecular neurobiology, 2016, Volume: 53, Issue:1

    Topics: Animals; Disease Models, Animal; Hippocampus; Infarction, Middle Cerebral Artery; Male; Mice; Morpholines; Phosphatidylinositol 3-Kinases; Pyrroles; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury; TRPV Cation Channels

2016
Involvement of platelet-derived growth factor receptor β in fibrosis through extracellular matrix protein production after ischemic stroke.
    Experimental neurology, 2015, Volume: 264

    Topics: Animals; Brain; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Extracellular Matrix Proteins; Fibrosis; Gene Expression Regulation; Indoles; Infarction, Middle Cerebral Artery; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Pericytes; Pyrroles; Rats; Receptor, Platelet-Derived Growth Factor beta; RNA, Messenger; Time Factors

2015
Protection effect of atorvastatin in cerebral ischemia-reperfusion injury rats by blocking the mitochondrial permeability transition pore.
    Genetics and molecular research : GMR, 2014, Dec-18, Volume: 13, Issue:4

    Topics: Animals; Anticholesteremic Agents; Apoptosis; Atorvastatin; Brain Ischemia; Cytochromes c; Disease Models, Animal; Heptanoic Acids; Infarction, Middle Cerebral Artery; Male; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Pyrroles; Rats, Sprague-Dawley; Reperfusion Injury

2014
Potential role of anti-VEGF targeted therapies in cervical artery dissection: A case report.
    Revue neurologique, 2015, Volume: 171, Issue:8-9

    Topics: Angiogenesis Inhibitors; Aphasia; Bone Neoplasms; Carcinoma, Renal Cell; Carotid Artery, Internal, Dissection; Combined Modality Therapy; Endovascular Procedures; Hematoma; Humans; Hyperhomocysteinemia; Indoles; Infarction, Middle Cerebral Artery; Inflammation; Kidney Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Nephrectomy; Paresis; Protein Kinase Inhibitors; Pyrroles; Radiography; Radiotherapy, Adjuvant; Stents; Sunitinib; Vasa Vasorum; Vascular Endothelial Growth Factor A; Vitamin B 12 Deficiency

2015
Activation of transient receptor potential vanilloid 4 induces apoptosis in hippocampus through downregulating PI3K/Akt and upregulating p38 MAPK signaling pathways.
    Cell death & disease, 2015, Jun-04, Volume: 6

    Topics: Animals; Anthracenes; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Down-Regulation; Enzyme Activation; Hippocampus; Imidazoles; Infarction, Middle Cerebral Artery; JNK Mitogen-Activated Protein Kinases; Leucine; Male; MAP Kinase Signaling System; Mice; Mice, Inbred ICR; Morpholines; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Pyridines; Pyrroles; Sulfonamides; TRPV Cation Channels

2015
Possible involvement of basic FGF in the upregulation of PDGFRβ in pericytes after ischemic stroke.
    Brain research, 2016, Jan-01, Volume: 1630

    Topics: Animals; Brain; Brain Ischemia; Cell Hypoxia; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Fibroblast Growth Factor 2; Humans; Hydrogen-Ion Concentration; Infarction, Middle Cerebral Artery; Male; Mice, 129 Strain; Mice, Inbred C57BL; Pericytes; Pyrroles; Receptor, Platelet-Derived Growth Factor beta; Receptors, Fibroblast Growth Factor; Stroke; Up-Regulation

2016
GSK-3β inhibitor TWS119 attenuates rtPA-induced hemorrhagic transformation and activates the Wnt/β-catenin signaling pathway after acute ischemic stroke in rats.
    Molecular neurobiology, 2016, Volume: 53, Issue:10

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Brain Ischemia; Cerebral Hemorrhage; Claudin-3; Glycogen Synthase Kinase 3 beta; Infarction, Middle Cerebral Artery; Male; Permeability; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Rats, Sprague-Dawley; Stroke; Tissue Plasminogen Activator; Wnt Signaling Pathway; Zonula Occludens-1 Protein

2016
USP14 inhibitor attenuates cerebral ischemia/reperfusion-induced neuronal injury in mice.
    Journal of neurochemistry, 2017, Volume: 140, Issue:5

    Topics: Animals; Behavior, Animal; Brain Ischemia; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrroles; Pyrrolidines; Recovery of Function; Reperfusion Injury; Survival Analysis; Ubiquitin Thiolesterase

2017
Effect of lipid-lowering therapy on the progression of intracranial arterial stenosis.
    Journal of neurology, 2009, Volume: 256, Issue:2

    Topics: Aged; Anticholesteremic Agents; Atorvastatin; Cerebral Arteries; Constriction, Pathologic; Disease Progression; Female; Heptanoic Acids; Humans; Hyperlipidemias; Infarction, Middle Cerebral Artery; Intracranial Arteriosclerosis; Male; Middle Aged; Platelet Aggregation Inhibitors; Pyrroles; Secondary Prevention; Sex Distribution; Stroke; Treatment Outcome; Vertebrobasilar Insufficiency

2009
Vascular endothelial growth factor receptor-2 inhibition promotes cell death and limits endothelial cell proliferation in a neonatal rodent model of stroke.
    Stroke, 2010, Volume: 41, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Animals, Newborn; Apoptosis; Calpain; Caspase 3; Cell Proliferation; Cerebral Arteries; Disease Models, Animal; Endothelial Cells; Indoles; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Necrosis; Neovascularization, Physiologic; Pyrroles; Rats; Rats, Sprague-Dawley; Stroke; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

2010
Neuroprotection of early and short-time applying atorvastatin in the acute phase of cerebral ischemia: down-regulated 12/15-LOX, p38MAPK and cPLA2 expression, ameliorated BBB permeability.
    Brain research, 2010, Apr-14, Volume: 1325

    Topics: Acute Disease; Animals; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Atorvastatin; Blood-Brain Barrier; Brain; Brain Edema; Brain Ischemia; Capillary Permeability; Down-Regulation; Heptanoic Acids; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Phospholipases A2, Cytosolic; Pyrroles; Random Allocation; Rats; Rats, Sprague-Dawley; Stroke; Time Factors

2010
p120 catenin/αN-catenin are molecular targets in the neuroprotection and neuronal plasticity mediated by atorvastatin after focal cerebral ischemia.
    Journal of neuroscience research, 2010, Volume: 88, Issue:16

    Topics: alpha Catenin; Analysis of Variance; Animals; Atorvastatin; Brain Ischemia; Catenins; Cell Adhesion Molecules; Cell Death; Cerebral Cortex; Delta Catenin; Gene Expression Regulation; Heptanoic Acids; Hippocampus; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infarction, Middle Cerebral Artery; Longitudinal Studies; Male; Nerve Tissue Proteins; Neuronal Plasticity; Neuroprotective Agents; Protein Isoforms; Pyrroles; Rats; Rats, Wistar; Statistics, Nonparametric; Synapses

2010
Amlodipine and atorvastatin exert protective and additive effects via antiapoptotic and antiautophagic mechanisms after transient middle cerebral artery occlusion in Zucker metabolic syndrome rats.
    Journal of neuroscience research, 2011, Volume: 89, Issue:8

    Topics: Amlodipine; Animals; Antihypertensive Agents; Apoptosis; Atorvastatin; Autophagy; Brain; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Pyrroles; Rats; Rats, Zucker

2011
Small unruptured partially thrombosed aneurysms and stroke: report of three cases and review of the literature.
    Journal of neurointerventional surgery, 2012, Volume: 4, Issue:3

    Topics: Aspirin; Atorvastatin; Craniotomy; Echocardiography, Transesophageal; Fibrinolytic Agents; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infarction, Middle Cerebral Artery; Intracranial Aneurysm; Intracranial Embolism; Male; Middle Aged; Neurosurgical Procedures; Paresis; Pyrroles; Stroke; Tomography, X-Ray Computed; Ultrasonography, Doppler, Color

2012
Probucol and atorvastatin in combination protect rat brains in MCAO model: upregulating Peroxiredoxin2, Foxo3a and Nrf2 expression.
    Neuroscience letters, 2012, Feb-16, Volume: 509, Issue:2

    Topics: Animals; Atorvastatin; Body Fluids; Brain; Disease Models, Animal; Drug Therapy, Combination; Forkhead Box Protein O3; Forkhead Transcription Factors; Heptanoic Acids; Infarction, Middle Cerebral Artery; Male; NF-E2-Related Factor 2; Peroxiredoxins; Probucol; Pyrroles; Rats; Up-Regulation; Water

2012
Thrombin activity associated with neuronal damage during acute focal ischemia.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, May-30, Volume: 32, Issue:22

    Topics: Amino Acids; Analysis of Variance; Animals; Antithrombins; Arginine; Avoidance Learning; Brain Injuries; Cell Death; Cognition Disorders; Disease Models, Animal; Factor X; Fibrinolysin; Gene Expression Regulation; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Male; Maze Learning; Motor Activity; Nerve Tissue Proteins; Pipecolic Acids; Pyrroles; Rats; Reaction Time; Receptor, PAR-1; Sulfonamides; Thrombin; Time Factors

2012
Reduction of cerebral infarction in stroke-prone spontaneously hypertensive rats by statins associated with amelioration of oxidative stress.
    Stroke, 2005, Volume: 36, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Atorvastatin; Blood Pressure; Body Weight; Deoxyguanosine; Disease Models, Animal; Heptanoic Acids; Hydroxymethylglutaryl CoA Reductases; Infarction, Middle Cerebral Artery; Lipids; Lysine; Oxidative Stress; Pyrroles; Quinolines; Rats; Rats, Inbred SHR; Simvastatin; Survival Analysis

2005
Long-term protective effect of atorvastatin in permanent focal cerebral ischemia.
    Brain research, 2005, Aug-09, Volume: 1052, Issue:2

    Topics: Animals; Atorvastatin; Behavior, Animal; Blood Circulation; Brain Infarction; Brain Ischemia; Dizocilpine Maleate; Heptanoic Acids; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Motor Activity; Neuroprotective Agents; Psychomotor Performance; Pyrroles; Rats; Rats, Long-Evans; Recovery of Function; Staining and Labeling; Time; Time Factors

2005
Vascular endothelial growth factor mediates atorvastatin-induced mammalian achaete-scute homologue-1 gene expression and neuronal differentiation after stroke in retired breeder rats.
    Neuroscience, 2006, Aug-25, Volume: 141, Issue:2

    Topics: Analysis of Variance; Animals; Antibodies; Atorvastatin; Basic Helix-Loop-Helix Transcription Factors; Cell Differentiation; Gene Expression; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Motor Activity; Neurons; Pyrroles; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tubulin; Vascular Endothelial Growth Factor A

2006
The PI3K/Akt pathway mediates the neuroprotective effect of atorvastatin in extending thrombolytic therapy after embolic stroke in the rat.
    Arteriosclerosis, thrombosis, and vascular biology, 2007, Volume: 27, Issue:11

    Topics: Animals; Atorvastatin; Biosynthetic Pathways; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Early Growth Response Protein 1; Fibrinolytic Agents; Heptanoic Acids; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyrroles; Rats; Rats, Wistar; Tissue Plasminogen Activator; Vascular Endothelial Growth Factor A

2007
Atorvastatin upregulates type III nitric oxide synthase in thrombocytes, decreases platelet activation, and protects from cerebral ischemia in normocholesterolemic mice.
    Stroke, 2000, Volume: 31, Issue:10

    Topics: Animals; Aorta; Atorvastatin; beta-Thromboglobulin; Blood Coagulation; Blood Platelets; Brain Ischemia; Cholesterol; Dose-Response Relationship, Drug; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infarction, Middle Cerebral Artery; Mice; Mice, Knockout; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Platelet Activation; Platelet Factor 4; Pyrroles; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; rho GTP-Binding Proteins; RNA, Messenger; Up-Regulation

2000