pyrroles and Hypertrophy, Right Ventricular

Topics: Animals; Cell Hypoxia; Disease Models, Animal; Fibrosis; Heart Ventricles; Humans; Hydrogen-Ion Concentration; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Indoles; Male; Mice; Pulmonary Artery; Pulmonary Circulation; Pyrroles; Vascular Endothelial Growth Factor A; Vascular Remodeling; Ventricular Remodeling

Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetamides; Animals; Cell Proliferation; Collagen Type I; Disease Models, Animal; Heart Ventricles; Hemodynamics; Hypertrophy, Right Ventricular; Hypoxia; Indoles; Lung; Male; Pulmonary Arterial Hypertension; Pyrazines; Pyrroles; Rats, Sprague-Dawley; Receptors, Epoprostenol; Systole; Vascular Remodeling

Topics: Animals; Clorgyline; Disease Models, Animal; Disease Progression; Heart Ventricles; Humans; Hypertrophy, Right Ventricular; Indoles; Monoamine Oxidase; Oxidative Stress; Pulmonary Arterial Hypertension; Pulmonary Artery; Pyrroles; Rats; Vascular Remodeling; Vascular Stiffness; Vasodilation

Topics: Animals; Antihypertensive Agents; Coronary Angiography; Coronary Vessels; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Hypertrophy, Right Ventricular; Hypoxia; Indoles; Monocrotaline; Predictive Value of Tests; Pulmonary Arterial Hypertension; Pyrimidines; Pyrroles; Rats, Sprague-Dawley; Severity of Illness Index; Sulfonamides; Synchrotrons; Vasodilation; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Remodeling

Topics: Animals; Citric Acid Cycle; Fatty Acids; Glucose; Heart Ventricles; Humans; Hypertrophy, Right Ventricular; Hypoxia; Indoles; Oxidation-Reduction; Pulmonary Arterial Hypertension; Pyrroles; Rats; Rats, Sprague-Dawley; Ventricular Remodeling

Topics: Animals; Cell Proliferation; Cell Survival; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Indoles; Male; Myocytes, Cardiac; Protein Kinase Inhibitors; Pulmonary Artery; Pyrroles; Rats, Sprague-Dawley; TOR Serine-Threonine Kinases; Ventricular Remodeling

Topics: Animals; Blotting, Western; Fibrosis; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Indoles; Lung; Male; Metabolomics; Pulmonary Artery; Pyrroles; Rats; Rats, Sprague-Dawley; Ventricular Remodeling

Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Imatinib Mesylate; Indoles; Male; Monocrotaline; Nestin; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-raf; Pulmonary Artery; Pyrroles; Rats, Wistar; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction; Sunitinib; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Vascular Remodeling; Ventricular Function, Right; Ventricular Remodeling

Topics: Animals; Cell Survival; Cells, Cultured; Curcumin; Hypertrophy; Hypertrophy, Right Ventricular; Hypoxia; Male; Mitochondria; Myocytes, Cardiac; Pyrroles; Quinolines; Rats; Rats, Sprague-Dawley

Topics: Animals; Antihypertensive Agents; Arterial Pressure; Autophagy; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Indoles; Male; Monocrotaline; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pulmonary Artery; Pyrroles; Rats, Wistar; Signal Transduction; Sorafenib; Vascular Remodeling; Ventricular Function, Right; Ventricular Remodeling

Topics: Animals; Arterial Pressure; Cells, Cultured; Disease Models, Animal; Fibrosis; Hypertrophy, Right Ventricular; Hypoxia; Indoles; Male; Mesenchymal Stem Cell Transplantation; Myocardial Contraction; Myocardium; Pulmonary Arterial Hypertension; Pulmonary Artery; Pyrroles; Rats, Sprague-Dawley; Recovery of Function; Regeneration; Tissue Scaffolds; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Remodeling; von Willebrand Factor

Topics: Adult; Aged; Animals; Apoptosis; Arterial Pressure; Bone Morphogenetic Protein Receptors, Type II; Case-Control Studies; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Female; Glycation End Products, Advanced; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Indoles; Male; Middle Aged; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; PPAR gamma; Pulmonary Artery; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA Interference; S100 Proteins; Signal Transduction; STAT3 Transcription Factor; Transfection; Up-Regulation

Topics: Angiogenesis Inhibitors; Animals; Circadian Rhythm; Disease Models, Animal; Disease Progression; Echocardiography; Heart Ventricles; Hemodynamics; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Indoles; Lung; Male; Pulmonary Artery; Pyrroles; Rats; Rats, Sprague-Dawley; Systole; Telemetry; Tunica Intima; Vascular Remodeling

Topics: Adventitia; Animals; Antihypertensive Agents; Cell Movement; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Matrix; Familial Primary Pulmonary Hypertension; Fibroblasts; HEK293 Cells; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Indoles; Male; Mice; Mice, Inbred C57BL; Monocrotaline; NADPH Oxidase 4; NADPH Oxidases; Pulmonary Artery; Pyrroles; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Time Factors; Transfection; Up-Regulation

Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Indoles; Male; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Sulfonamides; Time Factors; Vascular Endothelial Growth Factor A

Topics: Animals; Collagen; Cyclic AMP-Dependent Protein Kinases; Echocardiography; Fibroblasts; Fibrosis; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Iloprost; Indoles; Male; Matrix Metalloproteinase 9; Microscopy, Phase-Contrast; Physical Conditioning, Animal; Procollagen; Pyrroles; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transforming Growth Factor beta1; Vasodilator Agents; Ventricular Function, Right

Topics: Animals; Apelin; Arterioles; Cells, Cultured; Disease Models, Animal; Drug Evaluation, Preclinical; Endothelial Cells; Fibroblast Growth Factor 2; Hemodynamics; Histone Deacetylase Inhibitors; Hydroxamic Acids; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Intercellular Signaling Peptides and Proteins; Male; MEF2 Transcription Factors; MicroRNAs; Monocrotaline; Pulmonary Artery; Pyrroles; Rats; Rats, Sprague-Dawley; RNA Interference; RNA, Small Interfering; Transcription, Genetic

Topics: Acetylcholine; Animals; Atorvastatin; Blotting, Western; Body Weight; Caspase 3; Celecoxib; Cyclooxygenase Inhibitors; Disease Progression; Drug Combinations; Hemodynamics; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardium; Nitric Oxide Synthase Type III; Pulmonary Artery; Pyrazoles; Pyrroles; Rats; Rats, Wistar; Sulfonamides; Survival Analysis; Vasodilator Agents

Topics: Animals; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Indoles; Lung; Male; Natriuretic Agents; Natriuretic Peptide, C-Type; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Vascular Endothelial Growth Factor

Topics: Animals; Apoptosis; Blood Pressure; Blotting, Western; Caspase 3; Cell Proliferation; Cyclic GMP; Guanylate Cyclase; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Immunohistochemistry; Indoles; Lung; Male; Nitric Oxide Synthase Type III; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Pyrazoles; Pyrimidines; Pyrroles; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Sildenafil Citrate; Soluble Guanylyl Cyclase; Sulfones; Time Factors; Treatment Outcome

Topics: Angiography; Animals; Animals, Newborn; Birth Weight; Chronic Disease; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Indoles; Lung; Pulmonary Alveoli; Pulmonary Artery; Pulmonary Circulation; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Stress, Physiological

Topics: Acetylcysteine; Animals; Apoptosis; Disease Models, Animal; Dose-Response Relationship, Drug; Emphysema; Heme Oxygenase-1; Hypertrophy, Right Ventricular; Indoles; Lung; Male; Oxidative Stress; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Vascular Endothelial Growth Factor