Page last updated: 2024-08-18

pyrroles and Hepatic Failure

pyrroles has been researched along with Hepatic Failure in 9 studies

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (33.33)	29.6817
2010's	5 (55.56)	24.3611
2020's	1 (11.11)	2.80

Authors

Authors	Studies
Igawa, Y; Ishizuka, H; Ishizuka, T; Shimizu, T; Watanabe, A; Yamada, M	1
Bijarnia, M; De Simone, P; Isoneimi, H; Klupp, J; Krishnan, I; Pascher, A; Pirenne, J; Pratschke, J; Salamé, E	1
Levy, G; Trotter, JF	1
Liu, CY; Shields, AF; Weise, AM	1
Akyurek, N; Benekli, M; Buyukberber, S; Coskun, U; Demirci, U; Karakan, T; Tonyali, O; Yildiz, R	1
Gao, H; Li, N; Lin, G; Wang, JY; Zhang, SC	1
Ariad, S; Lazarev, I; Mermershtain, W; Shani-Shrem, N	1
Erhart, KH; Graziadei, IW; Obermoser, GE; Sepp, NT; Vogel, W	1
Bernd, C; Miles, S; Noy, A; Politsmakher, A; von Roenn, J	1

Trials

2 trial(s) available for pyrroles and Hepatic Failure

Article	Year
Physiologically based pharmacokinetic modelling to predict the clinical effect of CYP3A inhibitors/inducers on esaxerenone pharmacokinetics in healthy subjects and subjects with hepatic impairment. European journal of clinical pharmacology, 2022, Volume: 78, Issue:1 Topics: Antihypertensive Agents; Area Under Curve; Computer Simulation; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Healthy Volunteers; Humans; Itraconazole; Japan; Liver Failure; Metabolic Clearance Rate; Models, Biological; Pyrroles; Rifampin; Sulfones	2022
Protein kinase C inhibitor sotrastaurin in de novo liver transplant recipients: a randomized phase II trial. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2015, Volume: 15, Issue:5 Topics: Adult; Aged; Biopsy; Enzyme Inhibitors; Female; Glomerular Filtration Rate; Graft Rejection; Humans; Immunosuppressive Agents; Incidence; Kaplan-Meier Estimate; Kidney Transplantation; Liver Failure; Liver Transplantation; Male; Middle Aged; Protein Kinase C; Pyrroles; Quinazolines; Tacrolimus; Time Factors; Treatment Outcome	2015

Article

Year

Physiologically based pharmacokinetic modelling to predict the clinical effect of CYP3A inhibitors/inducers on esaxerenone pharmacokinetics in healthy subjects and subjects with hepatic impairment.

European journal of clinical pharmacology, 2022, Volume: 78, Issue:1

Topics: Antihypertensive Agents; Area Under Curve; Computer Simulation; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Healthy Volunteers; Humans; Itraconazole; Japan; Liver Failure; Metabolic Clearance Rate; Models, Biological; Pyrroles; Rifampin; Sulfones

2022

Protein kinase C inhibitor sotrastaurin in de novo liver transplant recipients: a randomized phase II trial.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2015, Volume: 15, Issue:5

Topics: Adult; Aged; Biopsy; Enzyme Inhibitors; Female; Glomerular Filtration Rate; Graft Rejection; Humans; Immunosuppressive Agents; Incidence; Kaplan-Meier Estimate; Kidney Transplantation; Liver Failure; Liver Transplantation; Male; Middle Aged; Protein Kinase C; Pyrroles; Quinazolines; Tacrolimus; Time Factors; Treatment Outcome

2015

Other Studies

7 other study(ies) available for pyrroles and Hepatic Failure

Article	Year
Sotrastaurin in liver transplantation: has it had a fair trial? American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2015, Volume: 15, Issue:5 Topics: Enzyme Inhibitors; Female; Humans; Liver Failure; Liver Transplantation; Male; Protein Kinase C; Pyrroles; Quinazolines	2015
Fatal liver failure in a patient on acetaminophen treated with sunitinib malate and levothyroxine. The Annals of pharmacotherapy, 2009, Volume: 43, Issue:4 Topics: Acetaminophen; Drug Therapy, Combination; Fatal Outcome; Female; Humans; Indoles; Liver Failure; Middle Aged; Pyrroles; Sunitinib; Thyroxine	2009
Imatinib mesylate-induced acute liver failure in a patient with gastrointestinal stromal tumors. Medical oncology (Northwood, London, England), 2010, Volume: 27, Issue:3 Topics: Acute Disease; Anti-Inflammatory Agents; Antineoplastic Agents; Benzamides; Chemical and Drug Induced Liver Injury; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Intestinal Neoplasms; Liver; Liver Failure; Middle Aged; Peritoneal Neoplasms; Piperazines; Prednisolone; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Sunitinib	2010
Definitive diagnosis of hepatic sinusoidal obstruction syndrome induced by pyrrolizidine alkaloids. Journal of digestive diseases, 2012, Volume: 13, Issue:1 Topics: Adult; Aged; Ascites; Biomarkers; Blood Proteins; Drugs, Chinese Herbal; Female; Hepatic Veno-Occlusive Disease; Humans; Liver Failure; Middle Aged; Pyrroles; Pyrrolizidine Alkaloids	2012
Fatal liver failure in a patient treated with sunitinib for renal cell carcinoma. Clinical genitourinary cancer, 2013, Volume: 11, Issue:1 Topics: Angiogenesis Inhibitors; Carcinoma, Renal Cell; Fatal Outcome; Humans; Indoles; Kidney Neoplasms; Liver Failure; Male; Middle Aged; Pyrroles; Sunitinib	2013
Drug-induced lupus-like syndrome associated with severe autoimmune hepatitis. Lupus, 2003, Volume: 12, Issue:5 Topics: Anticholesteremic Agents; Atorvastatin; Female; Hepatitis, Autoimmune; Heptanoic Acids; Humans; Immunosuppressive Agents; Liver; Liver Failure; Lupus Erythematosus, Systemic; Middle Aged; Pyrroles	2003
Fatal hepatorenal failure and thrombocytopenia with SU5416, a vascular endothelial growth factor Flk-1 receptor inhibitor, in AIDS-Kaposi's sarcoma. AIDS (London, England), 2007, Jan-02, Volume: 21, Issue:1 Topics: Acquired Immunodeficiency Syndrome; Angiogenesis Inhibitors; Fatal Outcome; Humans; Indoles; Liver Failure; Male; Middle Aged; Pyrroles; Renal Insufficiency; Sarcoma, Kaposi; Skin Neoplasms	2007