Page last updated: 2024-08-18

pyrroles and Gastrointestinal Stromal Tumors

pyrroles has been researched along with Gastrointestinal Stromal Tumors in 344 studies

Research

Studies (344)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	115 (33.43)	29.6817
2010's	195 (56.69)	24.3611
2020's	34 (9.88)	2.80

Authors

Authors	Studies
Doki, Y; Eguchi, H; Hirota, S; Kurokawa, Y; Makino, T; Motoori, M; Nakajima, K; Nishida, T; Omori, T; Saito, T; Takahashi, T; Tanaka, K; Teranishi, R; Yamamoto, K; Yamashita, K	1
Doi, T; Honma, Y; Iwagami, S; Komatsu, Y; Kurokawa, Y; Naito, Y; Nishida, T; Sawaki, A; Takahashi, T	1
Fu, Q; Jiang, X; Jing, Y; Peng, H; Rexiti, K; Tao, S; Wei, X; Xiong, F	1
Catania, C; Cocorocchio, E; Conforti, F; Corti, C; Curigliano, G; de Pas, T; Ferrucci, PF; Pala, L; Queirolo, P	1
Ben Kridis, W; Charfeddine, S; Khanfir, A; Masmoudi, S	1
Cai, S; Cao, H; Cui, Y; Deng, Y; Hu, J; Li, J; Qu, C; Ren, W; Shen, K; Shen, L; Tao, K; Wang, W; Wu, X; Yang, J; Yu, J; Zhang, J; Zhang, X; Zhang, Y; Zhao, W; Zheng, Z; Zhou, Y	1
Hirota, S; Ishikawa, T; Kanda, T; Matsumoto, Y; Saijo, Y; Sasaki, K	1
Hu, K; Shu, M; Wang, X; Zhang, H	1
McGregor, O; Moore, AS; Yeomans, S	1
DuBois, SG; Khosravan, R; Wetmore, C; Yu, Y	1
Dhillon, S	1
Aschenbrenner, DS	1
Desar, IME; Krens, SD; Mulder, SF; Smilde, T; van der Graaf, WTA; van Erp, NP; van Herpen, CML; Westerdijk, K	1
Gennatas, S; Huang, P; Jones, RL; Smrke, A	1
George, S; Serrano, C	1
Bauer, S; Cassier, PA; Chawla, SP; Eskens, F; Evans, EK; George, S; Heinrich, MC; Jones, RL; Kang, YK; Lauz, T; Mir, O; Roche, M; Rutkowski, P; Schöffski, P; Serrano, C; Tap, WD; Trent, J; Tugnait, M; von Mehren, M; Wolf, BB; Zhou, T	1
Wang, M; Zhao, G; Zhao, WY	1
Dong, Z; Li, J	1
Alzofon, N; Jimeno, A	1
Gomes, A; Mankoski, R; Miller, A; Nellesen, D; Norregaard, C; Proudman, D; Sullivan, E	1
Abaricia, SN; Angelis, MA; Bauer, S; Doyle, A; Havnaer, T; Jones, RL; Joseph, CP; Kang, YK; Polson, K; Riedel, RF; Roche, M; Schöffski, P; Serrano, C; Si, TD; Tetzlaff, ED; Trent, J; Zhou, T	1
Belinsky, MG; D'Souza, J; DeMatteo, R; Devarajan, K; Duncan, JS; Einarson, MB; Heinrich, MC; Johnson, KJ; Klug, L; Kozinova, M; Litwin, S; Rink, L; Sharipova, D; von Mehren, M; Ye, S; Zhou, Y	1
Bauer, S; Cassier, PA; Chawla, SP; Eskens, F; George, S; Gordon, M; Heinrich, MC; Jones, RL; Kang, YK; Meiri, E; Mir, O; Patel, S; Roche, M; Rutkowski, P; Schöffski, P; Serrano, C; Tap, WD; Trent, J; von Mehren, M; Zhou, T	1
Bauer, S; Cassier, PA; Chawla, SP; Eskens, FALM; George, S; Heinrich, MC; Jones, RL; Kang, YK; Mir, O; Roche, M; Rutkowski, P; Schöffski, P; Serrano, C; Tap, WD; von Mehren, M; Zhou, T	1
Chiroli, S; Dimitrijević, S; George, S; Heinrich, MC; Hoehn, G; Iannazzo, S; Mankoski, R; Shi, H; von Mehren, M	1
DuBois, SG; Khosravan, R; Verschuur, AC; Wang, E; Wetmore, C	1
Serrano, C	1
Dalhus, ML; Delgado, J; Egeland, EJ; Enzmann, H; Garcia-Ochoa, B; Payares-Herrera, C; Pignatti, F; Sancho-Lopez, A; Strøm, BO; Trullas-Jimeno, A; Wang, I	1
Bauer, S; Blach Rossen, P; Eriksson, M; Foukakis, T; Goplen, D; Hagberg, H; Hagberg, O; Hansson, L; Hohenberger, P; Joensuu, H; Krarup-Hansen, A; Pulkkanen, K; Reichardt, P; Sundby Hall, K	1
Díaz Valle, D; García Caride, S; Marquina, G	1
Bauer, S; Brahmi, M; George, S; He, K; Heinrich, MC; Hew, P; Hohenberger, P; Jones, RL; Kang, YK; Mir, O; Newberry, K; Pantaleo, MA; Patel, S; Roche, M; Rutkowski, P; Schöffski, P; Shen, L; Tap, WD; Trent, J; Villalobos, V; von Mehren, M; Zhou, Y	1
Henriques-Abreu, M; Serrano, C	1
Kubo, N; Takeuchi, N	1
Cubedo, R; García Del Muro, X; López-Guerrero, JA; Martín-Broto, J; Martínez, V; Poveda, A; Romero, I; Serrano, C; Valverde, C	1
Dong, Z; Gao, J; Gong, J; Li, J; Li, Y; Shen, L	1
Yousef, AJA	1
Benson, C; Chou, AJ; Magnan, H; Rutkowski, P	1
Jiang, T; Piao, D; Wang, W; Zhang, Z	1
Doki, Y; Kurokawa, Y; Makino, T; Miyazaki, Y; Mori, M; Nakajima, K; Saito, Y; Takahashi, T; Takiguchi, S; Tanaka, K; Yamasaki, M	1
Aoyama, T; Cho, H; Hayashi, T; Kano, K; Maezawa, Y; Masuda, M; Ogata, T; Oshima, T; Rino, Y; Sato, T; Yamada, T; Yoshikawa, T; Yukawa, N	1
Ishigame, T; Kase, K; Kenjo, A; Kimura, T; Kofunato, Y; Marubashi, S; Muto, M; Okada, R; Sato, N; Shimura, T; Watanabe, J	1
Gong, JF; Ji, JF; Li, J; Li, XT; Li, ZY; Shen, L; Sun, YS; Tang, L	1
Banerjee, D; Bhowmick, R; Manir, KS; Roy, C	1
Allenspach, K; Berger, EP; Du, Y; Fox, LE; Jergens, AE; Johannes, CM; Mochel, JP; Musser, ML; Powers, BE	1
Boichuk, S; Dunaev, P; Galembikova, A; Khromova, N; Kopnin, P; Micheeva, E; Novikova, M	1
Brzozowska, M; Czech, M; Potemski, P; Połowinczak-Przybyłek, J; Śliwczyński, A; Szafraniec-Buryło, S; Wierzba, W	1
Adamson, T; Antonescu, CR; Chi, P; Condy, M; D'Angelo, SP; Dickson, MA; Gounder, M; Hwang, S; Kelly, C; Keohan, ML; Mcfadyen, CR; Movva, S; Qin, LX; Rosenbaum, E; Singer, S; Tap, WD	1
Gao, J; Li, J; Shen, L; Sun, N; Tian, Y; Yuan, J	1
Ba-Ssalamah, A; Bareck, E; Brodowicz, T; Eisterer, W; Häfner, M; Högenauer, C; Kastner, U; Kühr, T; Längle, F; Liegl-Atzwanger, B; Ploner, F; Schoppmann, SF; Widmann, G; Wrba, F; Zacherl, J	1
Nishida, T; Tori, M; Yoshidome, K	1
Becker, CR; Berger, F; Englhart, E; Hittinger, M; Reiser, MF; Schlemmer, M; Schramm, N; Übleis, C	1
Chen, ZF; Chi, P; Guan, GX; Jiang, WZ; Liu, X; Lu, HS	1
Cao, H; Xu, J	1
Bracci, R; Cascinu, S; Maccaroni, E	1
Chen, LT; Chen, TS; Chiang, NJ; Hsueh, YS; Ko, CH; Li, CF; Lin, CL; Shan, YS; Shih, NY; Wang, LM; Yen, CC	1
De Giorgi, U	1
Akça, Z; Büyükçelik, A; Kaya, N; Mutlu, H	1
Feng, Q; Hongqian, G; Ruipeng, J; Weidong, G; Xiang, Y; Xitai, S	1
Lyseng-Williamson, KA	1
Fujiwara, T; Fujiwara, Y; Uno, F	1
Choi, YJ; Jo, J; Kang, YK; Lee, JJ; Park, I; Park, JH; Ryoo, BY; Ryu, JS; Ryu, MH; Tan, E; Yoo, C	1
Demetri, GD; Jagannathan, J; Kang, YK; Kim, HJ; Lee, JJ; Nam, BH; Ramaiya, N; Ryoo, BY; Ryu, MH; Yoo, C	1
Doi, T; Nishida, T	1
Jin, L; Kong, X; Lou, L; Quan, H; Xu, Y; Zhao, J	1
Fujita, T; Iwamoto, Y; Koike, H; Takeuchi, H; Tsujino, H	1
Akahoshi, S; Inoue, K; Kiyota, Y; Kiyozumi, Y; Motooka, Y; Yamaguchi, R; Yoshida, Y	1
Butrynski, JE; D'Adamo, D; Demetri, GD; Fisher, GA; Ganjoo, KN; George, S; Kamaya, A; McMillan, A; Morgan, JA; Villalobos, VM; Wagner, AJ	1
Collins, IM; Jefford, M; Lewin, J; Mooi, J; Urban, D	1
Choy, E; Demetri, GD; George, S; Jagannathan, JP; Kurra, V; Manola, J; Ramaiya, NH; Shinagare, AB; Urban, T	1
Antonescu, CR; Besmer, P; Cavnar, MJ; Cohen, NA; Crawley, MH; Dematteo, RP; Green, BL; Greer, JB; Kim, TS; Ku, AT; Pillarsetty, N; Popow, R; Rossi, F; Seifert, AM; Sorenson, EC; Veach, DR; Zeng, S	1
Liang, H	1
Liang, X; Shi, Y	1
Guillén, C; Llombart, B; Martorell-Calatayud, A; Nagore, E; Requena, C; Sanmartín, O; Sanz-Motilva, V; Serra-Guillén, C; Traves, V	1
Ashman, P; Cid Ruzafa, J; Desai, K; Khalid, JM; Maguire, A; Muston, D; Starczewska Amelio, JM; Tzivelekis, S	1
Benjamin, RS; Bergman, MA; Boles, S; Bui, MM; Casper, ES; Conrad, EU; DeLaney, TF; Ganjoo, KN; George, S; Gonzalez, RJ; Heslin, MJ; Kane, JM; Mayerson, J; McGarry, SV; Meyer, C; O'Donnell, RJ; Pappo, AS; Paz, IB; Pfeifer, JD; Randall, RL; Riedel, RF; Schuetze, S; Schupak, KD; Schwartz, HS; Sundar, H; Van Tine, BA; von Mehren, M; Wayne, JD	1
Chang, J; Connolly, MP; Currie, CJ; Poole, CD	1
Doi, T; Naito, Y; Nishida, T	1
Allred, R; de Wit, D; Demetri, GD; Gelderblom, H; Guchelaar, HJ; Khosravan, R; van Erp, NP; Wiltshire, R	1
Acin, Y; Adenis, A; Bertucci, F; Blay, JY; Blésius, A; Bompas, E; Bouché, O; Bui-Nguyen, B; Bulusu, VR; Chaigneau, L; Domont, J; Dubreuil, P; Hermine, O; Isambert, N; Le Cesne, A; Mansfield, CD; Moussy, A; Ray-Coquard, I; Van Tine, BA	1
Chen, JS; Chen, TW; Chen, YY; Cheng, CT; Chiang, KC; Hsu, CC; Jan, YY; Liu, YY; Tsai, CY; Tseng, JH; Wu, CE; Yeh, CN; Yeh, TS	1
Anjum, R; Bauer, S; Clackson, T; Eilers, G; Fletcher, JA; Garner, AP; Gozgit, JM; Heinrich, MC; Ketzer, J; Kohlmann, A; Ning, Y; Rivera, VM; Schrock, A; Serrano, C; Song, Y; Vodala, S; Wang, F; Wardwell, S; Zhou, T; Zhu, M	1
Alago, W; Brown, KT; Cornelis, F; Covey, A; Erinjeri, JP; Getrajdman, GI; Litchman, T; Maybody, M; Sofocleous, CT; Solomon, SB; Takaki, H	1
Liu, K; Wen, Y; Wu, L; Xiong, L; Yao, H; Zhang, Z	1
Blay, JY; Cassier, P; Dufresne, A; Heudel, P; Pissaloux, D; Ray-Coquard, I; Wang, Q	1
Boglione, A; Comandone, A	1
Biasco, G; Chen, L; Demetri, GD; Fly, K; Fumagalli, E; Gelderblom, H; Hurwitz, HI; Kaiser, PE; Kang, YK; Lechuga, MJ; Matczak, E; Reichardt, P; Rosen, LS; Rutkowski, P; Schuette, J; Seddon, B; Williams, CC; Yalcin, S	1
Demetri, GD; Doi, T; Kanda, T; Komatsu, Y; Kuss, I; Nishida, T; Sawaki, A; Yamada, Y	1
Egawa, C; Goto, T; Hashimoto, T; Ishida, T; Kagawa, Y; Kato, T; Katsura, Y; Kimura, K; Kuroda, Y; Kusama, H; Matsushita, K; Morimoto, Y; Nakahira, S; Nakatsuka, S; Nitta, K; Ohmura, Y; Ohzono, K; Okishiro, M; Sakisaka, H; Sato, Y; Takeda, Y; Takeno, A; Tamura, S; Taniguchi, H	1
Hosaka, S; Kawamoto, S; Kikutake, T; Nagao, S; Umemoto, S; Yonemitsu, K; Yoshida, T	1
Lin, XK; Liu, XS; Shou, CH; Sun, JY; Yang, WL; Yu, JR; Zhang, Q	1
Bencsikova, B; Bortlicek, Z; Brabec, P; Jureckova, A; Kocak, I; Kocakova, I; Krejci, E; Spelda, S; Strenkova, J; Vyzula, R	1
Antonescu, CR; Beckman, MJ; Besmer, P; Cohen, NA; Crawley, MH; DeMatteo, RP; Green, BL; Greer, JB; Kim, TS; Rossi, F; Santamaria-Barria, JA; Seifert, AM; Sorenson, EC; Zeng, S	1
Pilotte, AP	1
He, Y; Zhang, X	1
Boccardi, V; Marano, L; Marrelli, D; Roviello, F	1
Houzawa, H; Komatsu, Y; Nishida, T; Ohki, E; Togo, K; Toyoshima, Y; Ueda, E; Ueno, N; Yoshida, A	1
Badalamenti, G; Bronte, G; Casali, P; De Lisi, D; Dei Tos, AP; Frezza, AM; Fumagalli, E; Nannini, M; Pantaleo, MA; Russo, A; Santini, D; Spalato Ceruso, M; Tonini, G; Vincenzi, B	1
Gardner, EE; Rudin, CM	1
Blay, JY; Corsaro, M; Demetri, GD; Fly, K; Gelderblom, H; Goldstein, D; Gupta, S; Heinrich, MC; Huang, X; Im, SA; Kang, YK; Lechuga, MJ; Martini, JF; Reichardt, P; Rutkowski, P; Schöffski, P; Schuette, J; Soulières, D	1
Bauer, S; Bright, SA; Butini, S; Campiani, G; Greene, LM; Kinsella, P; Pollock, JK; Williams, DC; Zisterer, DM	1
Ando, T; Hosokawa, A; Kajiura, S; Nakada, N; Nanjyo, S; Sugiyama, T	1
Adenis, A; Bertucci, F; Blay, JY; Bompas, E; Bouché, O; Cassier, P; Cesne, AL; Chauzit, E; Cropet, C; Duffaud, F; Gautier, J; Isambert, N; Italiano, A; Mir, O; Molimard, M; Pérol, D; Ray-Coquard, I; Rios, M; Toulmonde, M	1
Boichuk, S; Dunaev, P; Galembikova, A; Khaibullina, S; Khusnutdinov, R; Lombardi, V; Ramazanov, B; Zykova, S	1
Fumagalli, E; Khosravan, R; Motzer, RJ; Rini, BI	1
Boddy, AV; Galettis, P; Goulooze, SC; Martin, JH	1
Amantea, MA; Friberg, LE; Karlsson, MO; Schindler, E	1
Barysauskas, CM; Ben-Ami, E; Butrynski, JE; Choy, E; Corless, CL; Demetri, GD; Fletcher, JA; George, S; Heinrich, MC; Morgan, JA; Solomon, SM; Van den Abbeele, AD; von Mehren, M; Wagner, AJ; Yap, JT	1
Im, SA; Kang, YK; Kim, TY; Lee, SJ; Park, JO; Park, SR; Ryoo, BY; Ryu, MH; Son, MK	1
Maki, RG; Martínez-Marín, V	1
Braschi-Amirfarzan, M; Ramaiya, NH; Shinagare, AB; Steele, E; Tirumani, SH	1
Angenendt, P; Diehl, F; Fredebohm, J; Holtrup, F; Löber, AK; Mehnert, DH; van Rahden, V	1
Ha, HK; Kim, AY; Kim, HJ; Kim, JS; Lee, JS; Park, SH	1
Angelini, S; Biasco, G; Gatto, L; Hrelia, P; Nannini, M; Pantaleo, MA; Ravegnini, G; Sammarini, G; Saponara, M; Simeon, V; Urbini, M; Venturoli, N; Zenesini, C	1
Chen, T; Chen, Z; Feng, X; Li, G; Li, Y; Qiu, H; Sun, X; Tao, K; Yu, J; Zhang, P; Zhou, Z	1
Azouz, MM; Bouassida, M; Chelbi, E; El Bouchtili, S; Ezzine, H; Hamzaoui, L; Mahmoudi, M; Medhioub, M; Touinsi, H	1
Chen, TW; Chen, YY; Chiang, KC; Liu, CT; Liu, YY; Tsai, CY; Wang, SY; Yeh, CN; Yeh, TS	1
Baines, L; Elliott, JW; Parry, A; Swinbourne, F	1
Hueman, MT; Schulick, RD	1
Rutkowski, P; Siedlecki, JA; Symonides, M; Zdzienicki, M	1
Eisenberg, B; Flieder, D; Godwin, AK; Koumbi, D; Merkel, E; Pathak, H; Rink, L; Tarn, C; Testa, JR; von Mehren, M	1
Corless, CL; Demetri, GD; Fletcher, CD; Fletcher, JA; Heinrich, MC; Kepten, I; Le, C; Liegl, B; Zhu, M	1
Bex, M; Carmeliet, P; Decallonne, B; Dumez, H; Schöffski, P; Stefan, C; Wolter, P	1
Humphreys, BD; Obhrai, JS; Patel, TV	1
Stergiopoulos, K; Wu, S; Zhu, X	1
Reichardt, P	2
Hur, H; Jee, SB; Jeon, HM; Jung, SE; Kim, W; Park, AR	1
Bórquez Ma, P; Neveu C, R	1
Judson, IR	1
Antonescu, CR; Baum, CM; Cohen, DP; Corless, CL; Demetri, GD; Fletcher, CD; Fletcher, JA; Griffith, D; Harlow, A; Heinrich, MC; Huang, X; Maki, RG; McKinley, A; Ou, WB; Town, A	1
Alberti, L; Arifi, S; Blay, JY; Bringuier, PP; Cassier, PA; Dufresne, A; El Sayadi, H; Ray-Coquard, I; Scoazec, JY	1
Loong, HH; Yeo, W	1
Benhattar, J; Delaloye, AB; Elsig, V; Guillou, L; Leyvraz, S; Luthi, F; Michielin, O; Montemurro, M; Orcurto, MV; Prior, JO; Stupp, R	1
Brosa, M; Díaz, S; García del Muro, X; González, P; Grande, E; Paz-Ares, L	1
Beijnen, JH; Burger, DM; Desar, IM; Van der Graaf, WT; Van Herpen, CM; Van Hoesel, QG	1
Christensen, J; Demetri, GD; Deshmukh, GD; Diehl, W; DiNitto, JP; Emmett, MR; English, JM; Gajiwala, KS; Greig, MJ; He, YA; Jacques, SL; Lunney, EA; Marshall, AG; McTigue, M; Molina, D; Quenzer, T; Wells, PA; Wu, JC; Yu, X; Zhang, HM; Zhang, Y; Zou, A	1
Bernstein, ML	1
Sevinc, A	1
Blay, JY; Casali, PG; Cohen, DP; Demetri, GD; Deprimo, SE; George, S; Harmon, CS; Law, CN; Le Cesne, A; Morgan, JA; Ray-Coquard, I; Stephenson, P; Tassell, V	1
Blanke, CD; Fernandes, Gdos S; Freitas, D; Guedes, R; Hoff, PM	1
von Mehren, M; Watson, JC	1
Bertagnolli, MM; Raut, CP	1
Albritton, KH; Butrynski, JE; D'Amato, GZ; Demetri, GD; Heinrich, MC; Janeway, KA; Pedrazzoli, P; Picus, J; Schlemmer, M; Siena, S; Van Den Abbeele, AD	1
Chen, SY; Chiang, WC; Fang, CC; Kao, PC; Lin, ZZ	1
Ahlman, H; Nilsson, B; Nilsson, O	1
Hamada, Y; Shibata, A; Tahara, M; Yamaguchi, S	1
Doi, T; Hirota, S; Komatsu, Y; Nakajima, K; Nishida, T; Nishitani, A; Shirao, K; Takahashi, T	1
Sternberg, CN	1
Blay, JY	3
Bukowski, R; Flodgren, P; Ravaud, A; Schöffski, P	1
Gan, HK; Knox, JJ; Seruga, B	1
Gelderblom, H; Grünwald, V; Hartmann, JT; Joensuu, H; Leyvraz, S; Montemurro, M; Reichardt, P; Roth, A; Schöffski, P; Schütte, J; Seddon, B; von Moos, R; Weber, E; Wendtner, CM	1
Bovée, JV; Gelderblom, H; Hogendoorn, PC; Kroep, JR; van der Molen, AJ	1
Blay, JY; Reichardt, P	1
Chang, SE; Choi, JH; Kang, YK; Koh, JK; Lee, JL; Lee, MW; Lee, WJ; Moon, KC	1
Akyurek, N; Benekli, M; Buyukberber, S; Coskun, U; Demirci, U; Karakan, T; Tonyali, O; Yildiz, R	1
Eisterer, W; Ploner, F	1
Becker, CR; Berger, F; Nikolaou, K; Reiser, MF; Schinwald, N; Schlemmer, M; Sourbron, SP	1
Doi, T; Komatsu, Y; Li, Y; Muro, K; Nishida, T; Ohtsu, A; Shirao, K; Ueda, E	1
Antonescu, CR; Baum, CM; Bello, CL; Chen, MH; Cohen, DP; Corless, CL; Demetri, GD; Fletcher, CD; Fletcher, JA; George, S; Heinrich, MC; Huang, X; Maki, RG; Morgan, JA; Van den Abbeele, AD	1
Blanke, CD	1
Baum, CM; Blackstein, ME; Demetri, GD; Deprimo, SE; Garrett, CR; Harmon, CS; Huang, X; Schöffski, P; Shah, MH; Verweij, J	1
Kang, DY; Kim, S; Lee, HJ; Lim, JS; Song, IC; Yun, HJ	1
Atrash, F; Bar-Sela, G; Hadad, S; Haim, N; Kedem, E; Pollack, S; Shahar, E	1
D'Adamo, D	1
Anderson, R; Bond, M; Hoyle, M; Moxham, T; Napier, M	1
Agaram, NP; Antonescu, CR; Besmer, P; Clarkson, BD; Dematteo, RP; Guo, T; Hajdu, M; Maki, RG; Shinoda, H; Singer, S; Veach, D	1
Bertagnolli, MM; Butrynski, JE; Demetri, GD; Fletcher, CD; George, S; Manola, J; Morgan, JA; Raut, CP; Wagner, AJ; Wang, Q	1
Schöffski, P; Wolter, P	1
Biasco, G; Catena, F; Di Battista, M; Nannini, M; Pantaleo, MA	1
Hohenberger, P	1
Agaimy, A; Schneider-Stock, R	1
Bello, CL; Demetri, GD; Houk, BE; Motzer, RJ; Poland, B; Rosen, LS	1
Briaire-de Bruijn, IH; Gelderblom, H; Hogendoorn, PC; Jordanova, ES; Ottenhoff, TH; Savage, ND; van der Burg, SH; van Dongen, M; van Hall, T; Walburg, KV	1
Wang, ZY	1
Miyazaki, Y; Nishida, T; Takahashi, T	1
Patel, SR; Pisters, PW	1
Heng, DY; Kollmannsberger, C	1
Guillén-Ponce, C; Mena, AC; Pulido, EG	1
Gasent, JM; Grande, E; Grávalos, C	1
Blay, JY; Cassier, PA	1
Antonescu, CR; DeMatteo, RP; Demetri, GD; Ganjoo, KN; Maki, RG; Pisters, PW; Raut, CP; Riedel, RF; Schuetze, S; Sundar, HM; Trent, JC; von Mehren, M; Wayne, JD	1
Bonvalot, S; Cioffi, A; Dômont, J; Le Cesne, A; Tardieu, M	1
Ahlman, H; Andersson, A; Nilsson, B; Nilsson, E; Nilsson, O; Sjölund, K	1
Bayraktar, S; Bayraktar, UD; Rocha-Lima, CM	1
Benekli, M; Bilge Yilmaz, I; Buyukberber, S; Coskun, U; Demirci, U; Erdem, O; Ozturk, B	1
Blanke, C	2
Garralda Cabanas, E; Hitt, R; Homet Moreno, B	1
Cai, SR; Chen, CQ; Chen, JH; He, YL; Ma, JP; Wu, KM; Zhan, WH; Zhang, XH	1
Debiec-Rychter, M; Floris, G; Schöffski, P; Sciot, R; Wozniak, A	1
Dhaun, N; Webb, DJ	1
Danser, AH; Kappers, MH; Sleijfer, S; Sluiter, W; van den Meiracker, AH; van Esch, JH	1
Hara, K; Hijioka, S; Kawai, H; Kondo, S; Matsumoto, K; Mizuno, N; Niwa, Y; Sawaki, A; Tajika, M; Yamao, K	1
Bauer, S; Grabellus, F; Schmid, KW; Sheu, SY; Speich, N; Worm, K	1
Delank, S; Eich, H; Wendtner, CM	1
Beck, MY; Chang, HM; Choi, DR; Kang, YK; Kim, KP; Kim, TW; Lee, JL; Ryoo, BY; Ryu, MH; Yoo, C	1
Hirashima, Y; Kawano, S; Morinaga, R; Otsu, S; Sakashita, H; Shirao, K; Watanabe, K	1
Liang, ZY	1
Blanke, CD; Huse, DM	1
Beck, M; Chang, HM; Cho, Y; Choi, DR; Kang, YK; Kim, TW; Lee, JL; Ryoo, BY; Ryu, MH; Yoon, DH	1
Aubin, F; Blanke, CD	1
Alacacioglu, A; Camci, C; Dikilitas, M; Er, O; Kalender, ME; Sagol, O; Sari, I; Sevinc, A; Soyuer, I; Yilmaz, U	1
Bach-Gansmo, T; Bruland, ØS; Revheim, ME; Røe, K; Seierstad, T; Skretting, A	1
Chu, DT	1
Conley, A; George, S; Lazar, AJ; Nolden, L; Reynoso, D; Trent, JC; Wang, WL	1
Dudeck, O; Pink, D; Reichardt, P; Zeile, M	1
Ganjoo, KN; Patel, S	1
Cano Megías, M; Carrasco De La Fuente, M; González Albarrán, O; Menacho Román, M; Pérez López, G	1
Diebold, J; Hirschmann, A; Rössle, M	1
Raut, CP; Winer, JH	1
Kamiya, K; Kikuchi, H; Konno, H; Miyazaki, S; Ohta, M; Sakaguchi, T; Setoguchi, T; Yamamoto, M	1
Hanazaki, K; Ikezoe, T; Nishioka, C; Taguchi, T; Takezaki, Y; Yang, J; Yokoyama, A	1
Doi, T; Kakeji, Y; Kanda, T; Komatsu, Y; Nishida, T; Ohtsu, A; Onozawa, Y; Sawaki, A; Yamada, Y; Yamasaki, M	1
Blanke, CD; Picus, J; Pisters, PWT; Sirulnik, A; Stealey, E; Trent, JC; von Mehren, M	1
Bauer, S; Montemurro, M	1
Aglietta, M; Bono, P; Boselli, S; Casali, PG; Coco, P; De Braud, F; De Pas, T; Grignagni, G; Jalava, T; Joensuu, H; Kappeler, C; Laurent, D; Spitalieri, G; Spreafico, C; Toffalorio, F	1
Chen, MF; Chen, TW; Chen, YY; Cheng, CT; Jan, YY; Rau, KM; Yeh, CN	1
Nishida, T; Omori, T; Ueshima, S	1
Akimoto, H; Chinen, Y; Kawano, H; Kojo, M; Minami, K; Morita, K; Okamura, T; Saeki, H; Sakaguchi, Y; Sakamoto, Y; Soejima, Y; Sugiyama, M; Toh, Y	1
Blay, JY; Chaigneau, L; Curtit, E; Dobi, E; Kalbacher, E; Mansi, L; Nguyen, T; Pivot, X; Viel, E	1
Hatakeyama, K; Ishikawa, T; Kanda, T; Kosugi, S; Yajima, K	1
Debiec-Rychter, M; Faa, G; Floris, G; Normant, E; Schöffski, P; Sciot, R; Van Looy, T; Wellens, J; Wozniak, A	1
Danser, AH; de Krijger, RR; Eechoute, K; Kappers, MH; Leijten, F; Mathijssen, RH; Sleijfer, S; Smedts, FM; van den Meiracker, AH; van Esch, JH; Visser, TJ	1
Bang, YJ; Han, SW; Heo, DS; Im, SA; Kim, DW; Kim, JH; Kim, SH; Kim, TM; Kim, TY; Kim, WH; Koh, Y; Lee, HE; Lee, SH; Oh, DY	1
Debiec-Rychter, M; Faa, G; Floris, G; Machiels, K; Normant, E; Schöffski, P; Sciot, R; Stefan, C; Vanleeuw, U; Wozniak, A	1
Greineder, CF; Kohnstamm, S; Ky, B	1
Reichardt, A; Reichardt, P	1
Deol, R; Lamba, G; Malhotra, BK; Sahni, R; Shah, D	1
Kwak, JY; Lee, NR; Song, EK; Yhim, HY; Yim, CY	1
Nagahama, K; Takahashi, D; Tamura, T; Tanaka, H; Tsuura, Y	1
Francescutti, V; Hare, R; Jarkowski, A; Khushalani, N; Wilkinson, N	1
Patil, DT; Rubin, BP	1
Elders, A; Fraser, C; Hislop, J; Jenkinson, D; Mowatt, G; Petty, R; Sharma, P; Vale, L	1
Antonescu, C	1
Akkus, M; Baykara, M; Benekli, M; Buyukberber, S; Coskun, U; Dane, F; Dursun, A; Gonul, II; Sevinc, A; Yildiz, R	1
Patel, S	1
Adenis, A; Antonescu, CR; Blay, JY; Bompas, E; Bui, B; Casali, P; Cioffi, A; Coco, P; Coindre, JM; Debiec-Rychter, M; Duffaud, F; Isambert, N; Italiano, A; Keohan, ML; Le Cesne, A; Maki, RG; Rutkowski, P; Schöffski, P; Toulmonde, M	1
Caram, MV; Schuetze, SM	1
Kim, EJ; Zalupski, MM	1
Bennett, JJ; Rubino, MS	1
Bove, B; Cauchi, C; Davey, M; Engstrom, PF; Lee, J; Litwin, S; Lopez, M; Somaiah, N; von Mehren, M	1
Ashley, SW; Grover, S; Raut, CP	1
Chika, N; Kakimoto, M; Kikuchi, A; Koshiishi, H; Nishida, K; Okamura, T; Tokita, H; Yoshimura, T	1
Hazama, S; Inoue, Y; Oka, M; Suzuki, N; Yoshino, S	1
Blay, JY; Bui-Nguyen, B; Demetri, GD; Galetic, I; Gelderblom, H; Hsu, Y; McArthur, GA; Reichardt, P; Rutkowski, P; Schlemmer, M; Yazji, S	1
George, S; Hornick, JL; Jagannathan, JP; Ramaiya, NH; Shinagare, AB	1
Agulnik, M; Huyck, TK; Svetlichnaya, J; Wayne, JD	1
Brzeskwiniewicz, M; Bylina, E; Falkowski, S; Grzesiakowska, U; Klimczak, A; Kroc, J; Limon, J; Lugowska, I; Melerowicz, W; Mierzejewska, E; Nowecki, ZI; Osuch, C; Rutkowski, P; Siedlecki, JA; Switaj, T; Wasielewski, K; Woźniak, A	1
Lu, W; Lu, WQ	1
Koshenkov, VP; Rodgers, SE	1
Butrynski, JE; Choy, E; Corless, CL; Demetri, GD; Fletcher, JA; George, S; Heinrich, MC; Manola, JB; Morgan, JA; Solomon, SM; Tap, WD; Van den Abbeele, AD; von Mehren, M; Wagner, AJ; Wang, Q; Yap, JT; Zhu, M	1
Lai, EC; Lau, SH; Lau, WY	1
Gao, J; Hong, J; Li, J; Shen, L	1
Blay, JY; Casali, PG; Cohen, DP; Demetri, GD; Garrett, CR; Goldstein, D; Harmon, CS; Huang, X; Hurwitz, HI; Le Cesne, A; Leyvraz, S; McArthur, GA; Paz-Ares, L; Pousa, AL; Schöffski, P; Shah, MH; Tassell, V; Verweij, J; Xu, QC	1
Bonenkamp, JJ; de Wilt, JH; Gelderblom, H; Hartgrink, HH; Sleijfer, S; Tielen, R; van Coevorden, F; van der Graaf, WT; Verhoef, C	1
Donohue, JH; Nagorney, DM; Okuno, SH; Que, FG; Zaydfudim, V	1
Cohen, DP; Demetri, GD; George, S; Lechner, T; Li, S; Reichardt, P	1
Gallowitsch, HJ; Malle, P; Sorschag, M	1
Hong, JL; Li, J; Shen, L	1
Hiramatsu, Y; Kamiya, K; Kikuchi, H; Konno, H; Miyazaki, S; Ohta, M; Sakaguchi, T; Setoguchi, T	1
Nishida, T; Ueshima, S; Wakasugi, M	1
Benekli, M; Buyukberber, S; Cetin, B; Guz, G; Inal, S; Memis, L; Ozturk, SC; Turan, N	1
Bauer, S; Bitz, U; Blay, JY; Duffaud, F; Gelderblom, H; Joensuu, H; Montemurro, M; Pink, D; Rutkowski, P; Schütte, J; Trent, J	1
Akyol, M; Alacacioglu, A; Benekli, M; Buyuberber, S; Ciltas, A; Coskun, U; Dane, F; Gumus, M; Isikdogan, A; Kaplan, MA; Karaca, H; Kefeli, U; Ozdemir, N; Ozkan, M; Seker, M; Sevinc, A; Suner, A; Tarhan, MO; Yildiz, R	1
Cunningham, D; Waddell, T	1
Badalamenti, G; Bauer, S; Blackstein, M; Blay, JY; Casali, PG; Chung, J; Demetri, GD; Gelderblom, H; Hohenberger, P; Joensuu, H; Kang, YK; Kappeler, C; Kuss, I; Laurent, D; Le Cesne, A; Leahy, M; Maki, RG; Nguyen, BB; Nishida, T; Reichardt, P; Rutkowski, P; Schöffski, P; von Mehren, M; Xu, J	1
Aieta, M; Bochicchio, AM; Capobianco, A; Coccaro, M; Gallucci, G; Improta, G; Maurea, N; Tartarone, A; Tocchetti, CG; Zupa, A	1
Matsui, K; Moriyama, M; Nagata, T; Okumura, T; Omura, T; Sawada, S; Sekine, S; Shimada, Y; Tsukada, K; Yoshida, T; Yoshioka, I	1
Kawamoto, S; Kikutake, T; Yoshida, T	1
Funaki, H; Kaida, D; Kinami, S; Kosaka, T; Minato, H; Morioka, E; Nakano, Y; Nakata, S; Noguchi, M; Ohnishi, T; Ohno, Y; Omote, K; Takamura, H; Tomita, Y; Ueda, N	1
Godwin, AK; Ochs, MF; Rink, L; von Mehren, M; Zhou, Y	1
Buti, S; Donini, M; Passalacqua, R; Rossi, G; Rossi, V; Sergio, P	1
Susman, E	1
Atkins, M; Jones, CA; Kirkpatrick, P	1
Cools, J; Debiec-Rychter, M; Folens, C; Marynen, P; Mentens, N; Prenen, H; Schöffski, P; Sciot, R; Van Oosterom, A	1
Bertagnolli, MM; Demetri, GD; Desai, J; Fletcher, CD; George, S; Morgan, JA; Posner, M; Raut, CP; Zahrieh, D	1
Bandobashi, K; Ikezoe, T; Koeffler, HP; Nakatani, H; Nishioka, C; Taguchi, H; Taguchi, T; Yang, Y	1
King, CR	1
Ikezoe, T; Koeffler, HP; Nishioka, C; Taguchi, H; Taguchi, T; Yang, Y; Zhu, WG	1
Blanke, CD; Schnadig, ID	1
Joensuu, H	2
Baum, CM; Bello, CL; Blackstein, ME; Casali, PG; Demetri, GD; Desai, J; Fletcher, CD; Garrett, CR; George, S; Heinrich, MC; Huang, X; Judson, IR; McArthur, G; Morgan, JA; Shah, MH; van Oosterom, AT; Verweij, J	1
Vollmer, H	1
Antonescu, CR; Dupont, J; Linkov, I; Maki, RG; Seandel, M; Shia, J	1
Alexander, EK; Chen, MH; Demetri, GD; Desai, J; Dychter, SS; Frates, MC; George, S; Larsen, PR; Marqusee, E; Morgan, JA; Yassa, L	1
Blay, JY; de Balincourt, C; di Paola, ED; Duffaud, F; Fowst, C; Hogendoorn, PC; Judson, I; Le Cesne, A; Leahy, M; Ray-Coquard, I; van Glabbeke, M; Verweij, J	1
Buhaescu, I; Deray, G; Izzedine, H; Rixe, O	1
Deeks, ED; Keating, GM	1
Fletcher, JA; Rubin, BP	1
Dagher, R; Goodman, V; Jiang, JX; Justice, R; Mahjoob, K; Morse, D; Pazdur, R; Rock, EP; Verbois, SL	1
Chow, LQ; Eckhardt, SG	1
Abraham, S; Booth, BP; Chidambaram, N; Dagher, R; Gobburu, JV; Goodman, VL; Jiang, JX; Justice, R; Liang, CY; Mahjoob, K; Morse, DE; Pazdur, R; Ramchandani, RP; Rock, EP; Tang, S; Verbois, SL	1
Alberti, L; Blay, JY; Cassier, PA; Dufresne, A; Fayette, J; Ranchere, D; Ray-Coquard, I	1
von Mehren, M	1
Maki, RG	1
Fletcher, CD; Hornick, JL	1
de Lima Lopes, G; Rocha Lima, CM	1
Dinolfo, M; Hershman, JM; Mulay, M; Rosen, LS; Sugawara, M; Tomoda, C; Vanvugt, A; Wong, E	1
Baum, C; Beaudry, P; Bello, C; Demetri, GD; DePrimo, SE; Desai, J; Folkman, J; Force, J; Heymach, JV; Maki, R; Manola, J; Norden-Zfoni, A; Shalinsky, DR	1
Corless, CL; Heinrich, MC; Rubin, BP	1
Camci, C; Kalender, M; Sevinc, A; Sirikci, A; Tutar, E	1
MacIntyre, J	1
George, S	1
Beck-Peccoz, P; Bertuelli, R; Carletto, M; Casali, PG; Coco, P; Fugazzola, L; Mannavola, D; Vannucchi, G	1
Seynaeve, C; Sleijfer, S; Verweij, J; Wiemer, E	1
Siehl, J; Thiel, E	1
Benjamin, RS; Blanke, CD; Blay, JY; Casali, P; Choi, H; Corless, CL; Debiec-Rychter, M; DeMatteo, RP; Demetri, GD; Ettinger, DS; Fisher, GA; Fletcher, CD; Gronchi, A; Hohenberger, P; Hughes, M; Joensuu, H; Judson, I; Le Cesne, A; Maki, RG; Morse, M; Pappo, AS; Pisters, PW; Raut, CP; Reichardt, P; Tyler, DS; Van den Abbeele, AD; von Mehren, M; Wayne, JD; Zalcberg, J	1
Reid, TR; Saylor, PJ	1
Nishida, T	1
Bulusu, R; Carroll, N; Hatcher, H; Jessop, F; Judson, I; Murray, M; Williams, D	1
Demetri, G; Judson, I	1
Adams, VR; Leggas, M	1
Shen, L	1
Polyzos, A	1
Gratama, JW; Kraan, J; Sleijfer, S; Strijbos, MH	1
Corless, CL; Heinrich, MC	1
Dova, L; Fountzilas, G; Georgiou, I; Golfinopoulos, V; Malamou-Mitsi, V; Ntemou, A; Pavlidis, N; Pentheroudakis, G; Vartholomatos, G	1
Hopkins, TG; Marples, M; Stark, D	1
Cassiola, F; Chen, JH; Chen, MH; Chu, TF; Dallabrida, SM; Demetri, GD; Desai, J; Force, T; George, S; Harris, DM; Ismail, NS; Kerkela, R; Morgan, JA; Nguyen, L; Pravda, E; Rupnick, MA; Schoen, FJ; Van den Abbeele, AD; Woulfe, K; Zurakowski, D	1
Astorino, M; Biasco, G; Brandi, G; Castellucci, P; Catena, F; Di Battista, M; Di Scioscio, V; Pantaleo, MA; Piazzi, G; Santini, D; Saponara, M	1
Bui, B; Italiano, A	1
Holen, KD; Loconte, NK; Mulherin, B	1
Banzo, I; Barragan, J; Carril, JM; Jimenez-Bonilla, J; Martinez-Rodriguez, I; Portilla-Quattrociocchi, H; Quirce, R; Sainz-Esteban, A	1
Debiec-Rychter, M; Dziewirski, W; Grzesiakowska, U; Michej, W; Nowecki, Z; Ruka, W; Rutkowski, P; Siedlecki, JA; Szawłowski, A	1
Blackstein, ME; Chabot, I; LeLorier, J	1
Apice, G; Bruni, GS; Caponigro, F; Iaffaioli, RV; Milano, A	1
Hariharan, S; Lowry, S	1
Agulnik, M; Aranha, O; Stein, E	1
Fisher, GA; Srinivas, S; Telli, ML; Witteles, RM	1
Doi, T	1
Bieber, T; Homey, B; ten Freyhaus, K; Wilsmann-Theis, D	1
Calvo, E; Prat, A; Serrano, C; Valverde, C	1
Contreras-Hernández, I; Dávila-Loaiza, G; Garduño-Espinosa, J; Granados-García, V; Mould-Quevedo, JF; Petersen, JA; Salinas-Escudero, G; Silva, A; Villasís-Keever, MA	1

Reviews

101 review(s) available for pyrroles and Gastrointestinal Stromal Tumors

Article	Year
Hematologic toxicities of sunitinib in patients with gastrointestinal stromal tumors: a systematic review and meta-analysis. International journal of colorectal disease, 2022, Volume: 37, Issue:7 Topics: Anemia; Antineoplastic Agents; Gastrointestinal Stromal Tumors; Humans; Neutropenia; Pyrroles; Sunitinib; Thrombocytopenia	2022
Efficacy of post-first-line agents for advanced gastrointestinal stromal tumors following imatinib failure: A network meta-analysis. Cancer medicine, 2023, Volume: 12, Issue:11 Topics: Antineoplastic Agents; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Network Meta-Analysis; Protein Kinase Inhibitors; Pyrroles; Sunitinib	2023
Avapritinib: First Approval. Drugs, 2020, Volume: 80, Issue:4 Topics: Drug Approval; Gastrointestinal Stromal Tumors; Humans; Mutation; Protein Kinase Inhibitors; Pyrazoles; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Triazines	2020
Avapritinib in the treatment of PDGFRA exon 18 mutated gastrointestinal stromal tumors. Future oncology (London, England), 2020, Volume: 16, Issue:22 Topics: Exons; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Mutation; Pyrazoles; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Standard of Care; Triazines	2020
Gastrointestinal Stromal Tumor: Challenges and Opportunities for a New Decade. Clinical cancer research : an official journal of the American Association for Cancer Research, 2020, 10-01, Volume: 26, Issue:19 Topics: Apoptosis; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Molecular Targeted Therapy; Naphthyridines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrazoles; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Triazines; Urea	2020
Avapritinib for metastatic or unresectable gastrointestinal stromal tumors. Drugs of today (Barcelona, Spain : 1998), 2020, Volume: 56, Issue:9 Topics: Clinical Trials as Topic; Gastrointestinal Stromal Tumors; Humans; Mutation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrazoles; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Triazines; United States	2020
Population Pharmacokinetics of Sunitinib and its Active Metabolite SU012662 in Pediatric Patients with Gastrointestinal Stromal Tumors or Other Solid Tumors. European journal of drug metabolism and pharmacokinetics, 2021, Volume: 46, Issue:3 Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Indoles; Infant; Male; Models, Biological; Neoplasms; Pyrroles; Sunitinib; Young Adult	2021
New treatments in advanced gastrointestinal stromal tumor. Current opinion in oncology, 2021, 07-01, Volume: 33, Issue:4 Topics: Antineoplastic Agents; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Naphthyridines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrazoles; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Triazines; Urea	2021
The EMA assessment of avapritinib in the treatment of gastrointestinal stromal tumours harbouring the PDGFRA D842V mutation. ESMO open, 2021, Volume: 6, Issue:3 Topics: Adult; Gastrointestinal Stromal Tumors; Humans; Mutation; Pyrazoles; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Triazines	2021
GEIS guidelines for gastrointestinal sarcomas (GIST). Cancer treatment reviews, 2017, Volume: 55 Topics: Antineoplastic Agents; Combined Modality Therapy; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Molecular Targeted Therapy; Phenylurea Compounds; Proto-Oncogene Proteins c-kit; Pyridines; Pyrroles; Sunitinib	2017
Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumor after failure with imatinib and sunitinib treatment: A meta-analysis. Medicine, 2017, Volume: 96, Issue:48 Topics: Antineoplastic Agents; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Phenylurea Compounds; Pyridines; Pyrroles; Sunitinib	2017
[Molecular mechanism and therapeutic strategy for resistance to tyrosine kinase inhibitors in targeted treatment of gastrointestinal stromal tumors]. Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2013, Volume: 16, Issue:3 Topics: Antineoplastic Agents; Benzamides; Drug Resistance, Neoplasm; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sunitinib	2013
Regorafenib: a guide to its use in advanced gastrointestinal stromal tumor (GIST) after failure of imatinib and sunitinib. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, 2013, Volume: 27, Issue:5 Topics: Animals; Benzamides; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Drug Evaluation, Preclinical; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Phenylurea Compounds; Piperazines; Pyridines; Pyrimidines; Pyrroles; Sunitinib	2013
Prevalence of gastrointestinal stromal tumour (GIST) in the United Kingdom at different therapeutic lines: an epidemiologic model. BMC cancer, 2014, May-24, Volume: 14 Topics: Antineoplastic Agents; Benzamides; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Incidence; Indoles; Models, Statistical; Piperazines; Prevalence; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Rare Diseases; Registries; Sunitinib; Treatment Failure; United Kingdom	2014
Tyrosine kinase inhibitors in the treatment of unresectable or metastatic gastrointestinal stromal tumors. Expert opinion on pharmacotherapy, 2014, Volume: 15, Issue:14 Topics: Antineoplastic Combined Chemotherapy Protocols; Benzamides; Drug Resistance, Neoplasm; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Neoplasm Metastasis; Phenylurea Compounds; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-kit; Pyridines; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sunitinib	2014
Clinical efficacy of second-generation tyrosine kinase inhibitors in imatinib-resistant gastrointestinal stromal tumors: a meta-analysis of recent clinical trials. Drug design, development and therapy, 2014, Volume: 8 Topics: Antineoplastic Agents; Benzamides; Drug Resistance, Neoplasm; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Phenylurea Compounds; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Sunitinib; Treatment Outcome	2014
[Molecular biology of sarcoma and therapeutic choices]. Bulletin du cancer, 2015, Volume: 102, Issue:1 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Benzamides; Bone Neoplasms; Crizotinib; Denosumab; Dermatofibrosarcoma; Gastrointestinal Stromal Tumors; Gene Amplification; Gene Deletion; Giant Cell Tumor of Bone; Humans; Imatinib Mesylate; Indoles; Molecular Targeted Therapy; Phenylurea Compounds; Piperazines; Point Mutation; Prognosis; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Sarcoma; Sarcoma, Ewing; Sunitinib; Synovitis, Pigmented Villonodular; Translocation, Genetic	2015
Current management of patients with gastrointestinal stromal tumor receiving the multitargeted tyrosine kinase inhibitor sunitinib. Current medical research and opinion, 2015, Volume: 31, Issue:7 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Protein Kinase Inhibitors; Pyrroles; Sunitinib	2015
Duodenal gastrointestinal stromal tumor: From clinicopathological features to surgical outcomes. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2015, Volume: 41, Issue:7 Topics: Age Distribution; Antineoplastic Agents; Benzamides; Biopsy, Fine-Needle; Endoscopy, Gastrointestinal; Endosonography; Europe; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Immunohistochemistry; Indoles; Mutation; Pancreaticoduodenectomy; Phenylurea Compounds; Piperazines; Prevalence; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyridines; Pyrimidines; Pyrroles; Sex Distribution; Sunitinib; United States	2015
Population Pharmacokinetic/Pharmacodynamic Modeling of Sunitinib by Dosing Schedule in Patients with Advanced Renal Cell Carcinoma or Gastrointestinal Stromal Tumor. Clinical pharmacokinetics, 2016, Volume: 55, Issue:10 Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Body Weight; Carcinoma, Renal Cell; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gastrointestinal Stromal Tumors; Humans; Indoles; Male; Middle Aged; Models, Biological; Pyrroles; Racial Groups; Sex Factors; Sunitinib	2016
Knowns and Known Unknowns of Gastrointestinal Stromal Tumor Adjuvant Therapy. Gastroenterology clinics of North America, 2016, Volume: 45, Issue:3 Topics: Antineoplastic Agents; Chemotherapy, Adjuvant; Digestive System Surgical Procedures; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Neoadjuvant Therapy; Phenylurea Compounds; Proto-Oncogene Proteins c-kit; Pyridines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sunitinib	2016
Management of gastrointestinal stromal tumors. The Surgical clinics of North America, 2008, Volume: 88, Issue:3 Topics: Antineoplastic Agents; Benzamides; Esophageal Neoplasms; Esophagectomy; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Piperazines; Positron-Emission Tomography; Prognosis; Pyrimidines; Pyrroles; Risk Assessment; Sunitinib; Tomography, X-Ray Computed; Treatment Outcome	2008
Developments in targeted therapy of advanced gastrointestinal stromal tumors. Recent patents on anti-cancer drug discovery, 2008, Volume: 3, Issue:2 Topics: Antineoplastic Agents; Benzamides; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Receptors, Vascular Endothelial Growth Factor; Sunitinib	2008
Risk of hypertension and renal dysfunction with an angiogenesis inhibitor sunitinib: systematic review and meta-analysis. Acta oncologica (Stockholm, Sweden), 2009, Volume: 48, Issue:1 Topics: Angiogenesis Inhibitors; Carcinoma, Renal Cell; Gastrointestinal Stromal Tumors; Humans; Hypertension; Indoles; Kidney Diseases; Kidney Neoplasms; Protein Kinase Inhibitors; Pyrroles; Sunitinib	2009
Novel approaches to imatinib- and sunitinib-resistant GIST. Current oncology reports, 2008, Volume: 10, Issue:4 Topics: Angiogenesis Inhibitors; Benzamides; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Sunitinib	2008
[Gastrointestinal stromal tumors. An update]. Revista medica de Chile, 2008, Volume: 136, Issue:7 Topics: Antineoplastic Agents; Benzamides; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sunitinib	2008
Novel approaches to gastrointestinal stromal tumors resistant to imatinib and sunitinib. Current gastroenterology reports, 2008, Volume: 10, Issue:6 Topics: Antineoplastic Agents; Benzamides; Combined Modality Therapy; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Piperazines; Pyrimidines; Pyrroles; Signal Transduction; Sunitinib	2008
Perioperative treatment of gastrointestinal stromal tumors. Oncology (Williston Park, N.Y.), 2009, Volume: 23, Issue:1 Topics: Antineoplastic Agents; Benzamides; Chemotherapy, Adjuvant; Clinical Trials as Topic; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Neoadjuvant Therapy; Pharmacogenetics; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sunitinib	2009
Treatment of gastrointestinal stromal tumours: imatinib, sunitinib -- and then? Expert opinion on investigational drugs, 2009, Volume: 18, Issue:4 Topics: Animals; Antineoplastic Agents; Benzamides; Drug Design; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Piperazines; Pyrimidines; Pyrroles; Signal Transduction; Sunitinib	2009
[Pharmacology profile of sunitinib malate (Sutent) Capsules) and clinical findings on this drug]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2009, Volume: 133, Issue:4 Topics: Animals; Antineoplastic Agents; Capsules; Carcinoma, Renal Cell; Clinical Trials as Topic; Gastrointestinal Stromal Tumors; Humans; Indoles; Kidney Neoplasms; Neovascularization, Pathologic; Pyrroles; Receptor, Platelet-Derived Growth Factor beta; Sunitinib; Vascular Endothelial Growth Factor Receptor-2	2009
Sunitinib in solid tumors. Expert opinion on investigational drugs, 2009, Volume: 18, Issue:6 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Clinical Trials as Topic; Gastrointestinal Stromal Tumors; Humans; Indoles; Kidney Neoplasms; Molecular Structure; Neoplasms; Protein-Tyrosine Kinases; Pyrroles; Sunitinib	2009
Extra-abdominal subcutaneous metastasis of a gastrointestinal stromal tumor: report of a case and a review of the literature. Journal of cutaneous pathology, 2009, Volume: 36, Issue:5 Topics: Aged; Antineoplastic Agents; Benzamides; Biomarkers, Tumor; Bone Neoplasms; Carcinoma; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Immunohistochemistry; Indoles; Liver Neoplasms; Piperazines; Pyrimidines; Pyrroles; Soft Tissue Neoplasms; Subcutaneous Fat; Sunitinib	2009
Advanced gastrointestinal stromal tumor in Europe: a review of updated treatment recommendations. Expert review of anticancer therapy, 2009, Volume: 9, Issue:6 Topics: Antineoplastic Agents; Benzamides; Disease Progression; DNA Mutational Analysis; Europe; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Neoplasm Metastasis; Piperazines; Practice Guidelines as Topic; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sunitinib	2009
Pharmacological management of gastrointestinal stromal tumours: an update on the role of sunitinib. Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:2 Topics: Antineoplastic Agents; Clinical Trials as Topic; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Indoles; Pyrroles; Sunitinib; Treatment Outcome	2010
[Treatment of extensive disease]. Wiener medizinische Wochenschrift (1946), 2009, Volume: 159, Issue:15-16 Topics: Antineoplastic Agents; Benzamides; Clinical Trials as Topic; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Therapy, Combination; Follow-Up Studies; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Long-Term Care; Neoplasm Invasiveness; Piperazines; Pyrimidines; Pyrroles; Sunitinib	2009
Advances in the treatment of gastrointestinal stromal tumor. Advances in therapy, 2009, Volume: 26, Issue:9 Topics: Antineoplastic Agents; Benzamides; Combined Modality Therapy; Drug Delivery Systems; Drug Resistance, Neoplasm; Drugs, Investigational; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sunitinib	2009
Sunitinib for the treatment of gastrointestinal stromal tumours: a critique of the submission from Pfizer. Health technology assessment (Winchester, England), 2009, Volume: 13 Suppl 2 Topics: Antineoplastic Agents; Cost-Benefit Analysis; Drug Industry; Gastrointestinal Stromal Tumors; Humans; Indoles; Pyrroles; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Sunitinib	2009
Targeted therapies in the treatment of GIST: Adverse events and maximising the benefits of sunitinib through proactive therapy management. Acta oncologica (Stockholm, Sweden), 2010, Volume: 49, Issue:1 Topics: Antineoplastic Agents; Benzamides; Clinical Trials as Topic; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Piperazines; Pyrimidines; Pyrroles; Sunitinib	2010
Combined treatment strategies in gastrointestinal stromal tumors (GISTs) after imatinib and sunitinib therapy. Cancer treatment reviews, 2010, Volume: 36, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Benzamides; Combined Modality Therapy; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Sunitinib	2010
[Aspects of surgical treatment for gastro-intestinal stromal tumors]. Der Radiologe, 2009, Volume: 49, Issue:12 Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Benzamides; Combined Modality Therapy; Diagnostic Imaging; Disease Progression; Follow-Up Studies; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Laparoscopy; Minimally Invasive Surgical Procedures; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Staging; Piperazines; Pyrimidines; Pyrroles; Sunitinib	2009
[Gastrointestinal stromal tumors: evolution of a tumor concept from unclassifiable neoplasms to targeted molecular therapy]. Der Pathologe, 2010, Volume: 31, Issue:2 Topics: Antineoplastic Agents; Benzamides; DNA Mutational Analysis; Drug Delivery Systems; Gastrointestinal Stromal Tumors; Gastrointestinal Tract; Gene Expression Regulation, Neoplastic; Humans; Imatinib Mesylate; Indoles; Piperazines; Prognosis; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sequence Analysis, DNA; Sunitinib	2010
Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with cancer: results of a pharmacokinetic/pharmacodynamic meta-analysis. Cancer chemotherapy and pharmacology, 2010, Volume: 66, Issue:2 Topics: Adult; Aged; Antineoplastic Agents; Area Under Curve; Blood Pressure; Carcinoma, Renal Cell; Endpoint Determination; Fatigue; Female; Gastrointestinal Stromal Tumors; Humans; Indoles; Kidney Neoplasms; Leukocyte Count; Linear Models; Male; Middle Aged; Neoplasms; Neutrophils; Nonlinear Dynamics; Population; Pyrroles; Sunitinib	2010
[Bemusement and strategy on the efficacy of clinical application of targeted anticancer drugs]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 2009, Volume: 31, Issue:9 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents; Benzamides; Benzenesulfonates; Bevacizumab; Carcinoma, Hepatocellular; Carcinoma, Renal Cell; Deoxycytidine; Drug Delivery Systems; Gastrointestinal Stromal Tumors; Gemcitabine; Humans; Imatinib Mesylate; Indoles; Neoplasms; Niacinamide; Pancreatic Neoplasms; Phenylurea Compounds; Piperazines; Pyridines; Pyrimidines; Pyrroles; Sirolimus; Sorafenib; Sunitinib	2009
Gastrointestinal stromal tumor: a bridge between bench and bedside. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2009, Volume: 12, Issue:4 Topics: Animals; Antineoplastic Agents; Benzamides; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sunitinib	2009
Gastrointestinal stromal tumors: current management. Journal of surgical oncology, 2010, Oct-01, Volume: 102, Issue:5 Topics: Antineoplastic Agents; Benzamides; Chemotherapy, Adjuvant; Combined Modality Therapy; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Neoplasm Recurrence, Local; Piperazines; Pyrimidines; Pyrroles; Sunitinib	2010
Sunitinib. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 2010, Volume: 184 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Carcinoma, Renal Cell; Clinical Trials as Topic; Drug Interactions; Gastrointestinal Stromal Tumors; Humans; Indoles; Kidney Neoplasms; Neoplasms; Pyrroles; Sunitinib	2010
Understanding the molecular-based mechanism of action of the tyrosine kinase inhibitor: sunitinib. Anti-cancer drugs, 2010, Volume: 21 Suppl 1 Topics: Angiogenesis Inhibitors; Breast Neoplasms; Carcinoma, Renal Cell; Colonic Neoplasms; Drug Resistance, Neoplasm; Female; Gastrointestinal Stromal Tumors; Humans; Indoles; Lung Neoplasms; Neovascularization, Pathologic; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrroles; Sunitinib	2010
Molecular response prediction in gastrointestinal stromal tumors. Targeted oncology, 2010, Volume: 5, Issue:1 Topics: Animals; Benzamides; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Piperazines; Prognosis; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sunitinib	2010
Optimal use of targeted agents for advanced gastrointestinal stromal tumours. Oncology, 2010, Volume: 78, Issue:2 Topics: Antineoplastic Agents; Benzamides; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; DNA Mutational Analysis; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Neoplasm Staging; Piperazines; Pyrimidines; Pyrroles; Sunitinib; Survival Rate; Treatment Outcome	2010
[Focus on GIST management]. Bulletin du cancer, 2010, Volume: 97, Issue:6 Topics: Antineoplastic Agents; Benzamides; Benzenesulfonates; Chemotherapy, Adjuvant; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Niacinamide; Phenylurea Compounds; Piperazines; Piperidines; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Pyrroles; Sorafenib; Sunitinib; Thiazoles	2010
Molecular basis and management of gastrointestinal stromal tumors. World journal of gastroenterology, 2010, Jun-14, Volume: 16, Issue:22 Topics: Antineoplastic Agents; Benzamides; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sunitinib	2010
Tyrosine kinase inhibitors in treating soft tissue sarcomas: sunitinib in non-GIST sarcomas. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2010, Volume: 12, Issue:7 Topics: Antineoplastic Agents; Gastrointestinal Stromal Tumors; Humans; Indoles; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrroles; Sarcoma; Sunitinib	2010
Implications of mutational analysis for the management of patients with gastrointestinal stromal tumors and the application of targeted therapies. Cancer investigation, 2010, Volume: 28, Issue:8 Topics: Angiogenesis Inhibitors; Antineoplastic Agents; DNA Mutational Analysis; Exons; Gastrointestinal Stromal Tumors; Genotype; Humans; Indoles; Prognosis; Proto-Oncogene Proteins c-kit; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Risk Assessment; Sunitinib; Transcriptional Activation	2010
[Multimodality therapy concepts for soft tissue sarcomas]. Der Internist, 2010, Volume: 51, Issue:11 Topics: Antineoplastic Agents; Benzamides; Chemotherapy, Adjuvant; Combined Modality Therapy; Cross-Sectional Studies; Gastrointestinal Stromal Tumors; Humans; Hyperthermia, Induced; Imatinib Mesylate; Indoles; Neoadjuvant Therapy; Palliative Care; Piperazines; Prognosis; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Radiotherapy, Adjuvant; Sarcoma; Soft Tissue Neoplasms; Sunitinib	2010
Cost effectiveness of tyrosine kinase inhibitor therapy in metastatic gastrointestinal stromal tumors. Journal of medical economics, 2010, Volume: 13, Issue:4 Topics: Antineoplastic Agents; Benzamides; Cost-Benefit Analysis; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Models, Economic; Neoplasm Metastasis; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Sunitinib	2010
Metastatic gastrointestinal stromal tumors. Cancer chemotherapy and pharmacology, 2011, Volume: 67 Suppl 1 Topics: Antineoplastic Agents; Gastrointestinal Stromal Tumors; Humans; Indoles; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prognosis; Proto-Oncogene Proteins c-kit; Pyrroles; Salvage Therapy; Sunitinib	2011
[Clinical manifestation of targeted drugs in individualized therapy of malignant tumors]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 2010, Volume: 32, Issue:10 Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cyclophosphamide; Doxorubicin; Drug Delivery Systems; ErbB Receptors; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid; Lymphoma, Large B-Cell, Diffuse; Mutation; Neoplasms; Piperazines; Prednisone; Pyrimidines; Pyrroles; Remission Induction; Rituximab; Sunitinib; Vincristine	2010
Mechanisms of resistance to imatinib and sunitinib in gastrointestinal stromal tumor. Cancer chemotherapy and pharmacology, 2011, Volume: 67 Suppl 1 Topics: Antineoplastic Agents; Benzamides; Disease Progression; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sunitinib	2011
A decade of tyrosine kinase inhibitor therapy: Historical and current perspectives on targeted therapy for GIST. Cancer treatment reviews, 2011, Volume: 37, Issue:5 Topics: Adult; Angiogenesis Inhibitors; Benzamides; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Disease-Free Survival; Drug Delivery Systems; Enzyme Inhibitors; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Neoplasm Staging; Pilot Projects; Piperazines; Prognosis; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Sunitinib; Survival Analysis	2011
Current and emerging pharmacological treatments for gastrointestinal stromal tumour. Drugs, 2011, Feb-12, Volume: 71, Issue:3 Topics: Antineoplastic Agents; Benzamides; Drugs, Investigational; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Neoplasm Recurrence, Local; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sunitinib	2011
Management of recurrent gastrointestinal stromal tumors. Journal of surgical oncology, 2011, Volume: 104, Issue:8 Topics: Benzamides; Combined Modality Therapy; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Neoplasm Recurrence, Local; Piperazines; Pyrimidines; Pyrroles; Sunitinib	2011
Heart failure associated with sunitinib: lessons learned from animal models. Current hypertension reports, 2011, Volume: 13, Issue:6 Topics: AMP-Activated Protein Kinases; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Carcinoma, Renal Cell; Cardiotoxins; Disease Models, Animal; Gastrointestinal Stromal Tumors; Heart Failure; Humans; Indoles; Kidney Neoplasms; Mitochondria; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Risk Factors; Signal Transduction; Sunitinib	2011
[Gastrointestinal stromal tumour (GIST): current standards in multimodal management]. Zentralblatt fur Chirurgie, 2011, Volume: 136, Issue:4 Topics: Alleles; Benzamides; Chemotherapy, Adjuvant; Combined Modality Therapy; Disease-Free Survival; DNA Mutational Analysis; Exons; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Maintenance Chemotherapy; Neoplasm Invasiveness; Neoplasm Staging; Piperazines; Prognosis; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sunitinib	2011
Gastrointestinal stromal tumor: advances in diagnosis and management. Archives of pathology & laboratory medicine, 2011, Volume: 135, Issue:10 Topics: Benzamides; Diagnosis, Differential; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Piperazines; Platelet-Derived Growth Factor; Prognosis; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sunitinib	2011
Systematic review of escalated imatinib doses compared with sunitinib or best supportive care, for the treatment of people with unresectable/metastatic gastrointestinal stromal tumours whose disease has progressed on the standard imatinib dose. Journal of gastrointestinal cancer, 2012, Volume: 43, Issue:2 Topics: Antineoplastic Agents; Benzamides; Clinical Trials as Topic; Disease Progression; Disease-Free Survival; Dose-Response Relationship, Drug; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Piperazines; Pyrimidines; Pyrroles; Sunitinib; Treatment Outcome	2012
Gastrointestinal stromal tumors. Current topics in microbiology and immunology, 2012, Volume: 355 Topics: Antineoplastic Agents; Benzamides; Cell Proliferation; Drug Resistance, Neoplasm; Enzyme Activation; Exons; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Liver Neoplasms; Molecular Targeted Therapy; Mutation; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sunitinib	2012
Managing progressive disease in patients with GIST: factors to consider besides acquired secondary tyrosine kinase inhibitor resistance. Cancer treatment reviews, 2012, Volume: 38, Issue:5 Topics: Benzamides; Disease Progression; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Patient Compliance; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Sunitinib	2012
Advanced or metastatic gastrointestinal stromal tumors: systemic treatment options. Journal of surgical oncology, 2011, Volume: 104, Issue:8 Topics: Antineoplastic Agents; Benzamides; Drug Resistance, Neoplasm; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Neoplasm Metastasis; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sunitinib	2011
Systemic therapy for advanced gastrointestinal stromal tumors: beyond imatinib. Journal of surgical oncology, 2011, Volume: 104, Issue:8 Topics: Antineoplastic Agents; Benzamides; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Piperazines; Piperidines; Proto-Oncogene Proteins c-kit; Pyridines; Pyrimidines; Pyrroles; Receptors, Platelet-Derived Growth Factor; Sunitinib; Thiazoles	2011
Small intestine gastrointestinal stromal tumors. Current opinion in gastroenterology, 2012, Volume: 28, Issue:2 Topics: Antineoplastic Agents; Benzamides; Chemotherapy, Adjuvant; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Intestinal Neoplasms; Intestine, Small; Neoadjuvant Therapy; Neoplasm Metastasis; Piperazines; Prognosis; Pyrimidines; Pyrroles; Sunitinib	2012
[Resistance and treatment strategy of gastrointestinal stromal tumor target therapy]. Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2012, Volume: 15, Issue:3 Topics: Antineoplastic Agents; Benzamides; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Sunitinib	2012
Adjuvant therapy of gastrointestinal stromal tumors. Current opinion in oncology, 2012, Volume: 24, Issue:4 Topics: Benzamides; Chemotherapy, Adjuvant; Clinical Trials as Topic; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Sunitinib	2012
Current management of gastrointestinal stromal tumors--a comprehensive review. International journal of surgery (London, England), 2012, Volume: 10, Issue:7 Topics: Antineoplastic Agents; Benzamides; Combined Modality Therapy; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Piperazines; Pyrimidines; Pyrroles; Sunitinib	2012
FDG PET and FDG PET/CT in patients with gastrointestinal stromal tumours. Wiener medizinische Wochenschrift (1946), 2012, Volume: 162, Issue:19-20 Topics: Antineoplastic Agents; Benzamides; Blood Glucose; Fluorodeoxyglucose F18; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Molecular Targeted Therapy; Multimodal Imaging; Neoplasm Recurrence, Local; Piperazines; Positron-Emission Tomography; Prognosis; Pyrimidines; Pyrroles; Sensitivity and Specificity; Sunitinib; Tomography, X-Ray Computed; Treatment Outcome	2012
Role of preeclampsia-related angiogenic factors in sunitinib cardiotoxicity: two cases and review of the literature. Future oncology (London, England), 2013, Volume: 9, Issue:1 Topics: Adult; Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Antineoplastic Agents; Carcinoma, Renal Cell; Fatal Outcome; Female; Gastrointestinal Stromal Tumors; Humans; Indoles; Middle Aged; Pre-Eclampsia; Pregnancy; Pyrroles; Sunitinib; Ventricular Dysfunction, Left	2013
Multitargeted agents for therapeutically challenging tumor: an introduction for oncology nurses. ONS news, 2006, Volume: 21, Issue:8 Suppl Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Drug Delivery Systems; Drug Monitoring; Gastrointestinal Stromal Tumors; Humans; Indoles; Kidney Neoplasms; Niacinamide; Nurse's Role; Nursing Assessment; Oncology Nursing; Patient Education as Topic; Phenylurea Compounds; Pyridines; Pyrroles; Signal Transduction; Sorafenib; Sunitinib	2006
Gastrointestinal stromal tumors: imatinib and beyond. Current treatment options in oncology, 2006, Volume: 7, Issue:6 Topics: Antineoplastic Agents; Benzamides; Combined Modality Therapy; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Neoplasm Metastasis; Neoplasm Recurrence, Local; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Sunitinib	2006
Sunitinib. Drugs, 2006, Volume: 66, Issue:17 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Clinical Trials as Topic; Gastrointestinal Stromal Tumors; Humans; Indoles; Kidney Neoplasms; Pyrroles; Sunitinib	2006
KIT mutations in GIST. Current opinion in genetics & development, 2007, Volume: 17, Issue:1 Topics: Antineoplastic Agents; Benzamides; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; HSP90 Heat-Shock Proteins; Humans; Imatinib Mesylate; Indoles; Models, Biological; Mutation; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Signal Transduction; Sunitinib	2007
Sunitinib: from rational design to clinical efficacy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Mar-01, Volume: 25, Issue:7 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Carcinoma, Renal Cell; Clinical Trials as Topic; Drug Design; Gastrointestinal Stromal Tumors; Humans; Indoles; Kidney Neoplasms; Leukemia, Myeloid, Acute; Neoplasms; Protein Kinase Inhibitors; Pyrroles; Sunitinib	2007
Approval summary: sunitinib for the treatment of imatinib refractory or intolerant gastrointestinal stromal tumors and advanced renal cell carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Mar-01, Volume: 13, Issue:5 Topics: Antineoplastic Agents; Benzamides; Carcinoma, Renal Cell; Drug Approval; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Kidney Neoplasms; Piperazines; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Sunitinib; United States; United States Food and Drug Administration	2007
Emerging drugs for the treatment of soft tissue sarcomas. Expert opinion on emerging drugs, 2007, Volume: 12, Issue:1 Topics: Antineoplastic Agents; Benzamides; Dacarbazine; Doxorubicin; Gastrointestinal Stromal Tumors; Humans; Ifosfamide; Imatinib Mesylate; Indoles; Piperazines; Pyrimidines; Pyrroles; Sarcoma; Sunitinib	2007
Beyond imatinib: second generation c-KIT inhibitors for the management of gastrointestinal stromal tumors. Clinical colorectal cancer, 2006, Volume: 6 Suppl 1 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzamides; Bevacizumab; Clinical Trials as Topic; Dasatinib; Drug Resistance, Neoplasm; Everolimus; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Immunosuppressive Agents; Indoles; Niacinamide; Oligonucleotides; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sirolimus; Staurosporine; Sunitinib; Thiazoles	2006
Recent advances in therapy for gastrointestinal stromal tumors. Current oncology reports, 2007, Volume: 9, Issue:3 Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Benzamides; Combined Modality Therapy; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Neoplasm Metastasis; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Sunitinib	2007
The role of KIT in the management of patients with gastrointestinal stromal tumors. Human pathology, 2007, Volume: 38, Issue:5 Topics: Antineoplastic Agents; Benzamides; Drug Resistance, Neoplasm; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sunitinib	2007
Gastrointestinal stromal tumour. Lancet (London, England), 2007, May-19, Volume: 369, Issue:9574 Topics: Antineoplastic Agents; Benzamides; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Molecular Biology; Piperazines; Positron-Emission Tomography; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Risk Assessment; Sunitinib	2007
Second line therapies for the treatment of gastrointestinal stromal tumor. Current opinion in oncology, 2007, Volume: 19, Issue:4 Topics: Benzamides; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Neoplasm Recurrence, Local; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Sunitinib; Treatment Failure	2007
Pharmacologic application of sunitinib malate in the management of gastrointestinal stromal tumors. Clinical journal of oncology nursing, 2007, Volume: 11, Issue:2 Topics: Angiogenesis Inhibitors; Gastrointestinal Stromal Tumors; Humans; Indoles; Patient Education as Topic; Pyrroles; Sunitinib	2007
Sunitinib, a multitargeted tyrosine kinase inhibitor, in the management of gastrointestinal stromal tumor. Current oncology reports, 2007, Volume: 9, Issue:4 Topics: Antineoplastic Agents; Drug Administration Schedule; fms-Like Tyrosine Kinase 3; Gastrointestinal Stromal Tumors; Genotype; Humans; Indoles; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrroles; Receptors, Platelet-Derived Growth Factor; Sunitinib; Survival Rate; Vascular Endothelial Growth Factor A	2007
C-kit, GIST, and imatinib. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 2007, Volume: 176 Topics: Antineoplastic Agents; Benzamides; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sunitinib	2007
NCCN Task Force report: management of patients with gastrointestinal stromal tumor (GIST)--update of the NCCN clinical practice guidelines. Journal of the National Comprehensive Cancer Network : JNCCN, 2007, Volume: 5 Suppl 2 Topics: Advisory Committees; Benzamides; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Immunohistochemistry; Indoles; Piperazines; Practice Guidelines as Topic; Prognosis; Pyrimidines; Pyrroles; Sunitinib; Tomography, X-Ray Computed; United States	2007
Advances in the treatment of gastrointestinal stromal tumours. Annals of oncology : official journal of the European Society for Medical Oncology, 2007, Volume: 18 Suppl 10 Topics: Antineoplastic Agents; Benzamides; Disease Progression; Disease-Free Survival; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Piperazines; Pyrimidines; Pyrroles; Sunitinib	2007
Sunitinib malate for the treatment of metastatic renal cell carcinoma and gastrointestinal stromal tumors. Clinical therapeutics, 2007, Volume: 29, Issue:7 Topics: Age Factors; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Gastrointestinal Stromal Tumors; Humans; Indoles; Kidney Neoplasms; Lactation; Lung Neoplasms; Neuroendocrine Tumors; Pregnancy; Pyrroles; Receptor Protein-Tyrosine Kinases; Sunitinib	2007
Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma and various other solid tumors. The Journal of steroid biochemistry and molecular biology, 2008, Volume: 108, Issue:3-5 Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Renal Cell; Female; Gastrointestinal Stromal Tumors; Humans; Indoles; Kidney Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neuroendocrine Tumors; Pyrroles; Receptors, Platelet-Derived Growth Factor; Receptors, Vascular Endothelial Growth Factor; Sunitinib	2008
Molecular pathobiology of gastrointestinal stromal sarcomas. Annual review of pathology, 2008, Volume: 3 Topics: Benzamides; Gastrointestinal Stromal Tumors; Gene Expression Regulation, Neoplastic; Humans; Imatinib Mesylate; Indoles; Mutation; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sarcoma; Sunitinib	2008
Sunitinib in the management of gastrointestinal stromal tumours (GISTs). European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2008, Volume: 34, Issue:8 Topics: Antineoplastic Agents; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Indoles; Pyrroles; Sunitinib; Treatment Outcome	2008
[Gastrointestinal stromal tumors: molecular aspects and therapeutic implications]. Bulletin du cancer, 2008, Volume: 95, Issue:1 Topics: Antineoplastic Agents; Benzamides; Benzenesulfonates; Disease Progression; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Neoplasm Proteins; Niacinamide; Oligonucleotides; Phenylurea Compounds; Phthalazines; Piperazines; Piperidines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyridines; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sorafenib; Staurosporine; Sunitinib; Thiazoles	2008
Guillain-Barré syndrome after treatment with sunitinib malate? Oncology (Williston Park, N.Y.), 2008, Volume: 22, Issue:1 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Gastrointestinal Stromal Tumors; Guillain-Barre Syndrome; Humans; Indoles; Kidney Neoplasms; Pyrroles; Sunitinib	2008
Medical treatment of gastrointestinal stromal tumors: state of the art and future perspectives. Reviews on recent clinical trials, 2006, Volume: 1, Issue:1 Topics: Antineoplastic Agents; Benzamides; Chemotherapy, Adjuvant; Dioxoles; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Neoadjuvant Therapy; Niacinamide; Oligonucleotides; Phthalazines; Piperazines; Proto-Oncogene Mas; Pyridines; Pyrimidines; Pyrroles; Sunitinib; Tetrahydroisoquinolines; Trabectedin	2006
New therapeutic options in gastrointestinal stromal tumors. Oncology (Williston Park, N.Y.), 2008, Volume: 22, Issue:2 Topics: Antineoplastic Agents; Benzamides; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Sunitinib	2008
[GIST]. Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:5 Topics: Antineoplastic Agents; Benzamides; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Sunitinib	2008

Trials

47 trial(s) available for pyrroles and Gastrointestinal Stromal Tumors

Article	Year
Pimitespib in patients with advanced gastrointestinal stromal tumor (CHAPTER-GIST-301): a randomized, double-blind, placebo-controlled phase III trial. Annals of oncology : official journal of the European Society for Medical Oncology, 2022, Volume: 33, Issue:9 Topics: Antineoplastic Agents; Diarrhea; Double-Blind Method; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Pyrroles	2022
Efficacy and Safety of Avapritinib in Treating Unresectable or Metastatic Gastrointestinal Stromal Tumors: A Phase I/II, Open-Label, Multicenter Study. The oncologist, 2023, 02-08, Volume: 28, Issue:2 Topics: Antineoplastic Agents; Gastrointestinal Stromal Tumors; Humans; Mutation; Protein Kinase Inhibitors; Pyrroles	2023
Avapritinib in advanced PDGFRA D842V-mutant gastrointestinal stromal tumour (NAVIGATOR): a multicentre, open-label, phase 1 trial. The Lancet. Oncology, 2020, Volume: 21, Issue:7 Topics: Aged; Female; Follow-Up Studies; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Male; Middle Aged; Mutation; Prognosis; Pyrazoles; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Triazines	2020
Optimal Avapritinib Treatment Strategies for Patients with Metastatic or Unresectable Gastrointestinal Stromal Tumors. The oncologist, 2021, Volume: 26, Issue:4 Topics: Adult; Gastrointestinal Stromal Tumors; Humans; Mutation; Proto-Oncogene Proteins c-kit; Pyrazoles; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Triazines	2021
Avapritinib in unresectable or metastatic PDGFRA D842V-mutant gastrointestinal stromal tumours: Long-term efficacy and safety data from the NAVIGATOR phase I trial. European journal of cancer (Oxford, England : 1990), 2021, Volume: 145 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Male; Middle Aged; Mutation; Progression-Free Survival; Protein Kinase Inhibitors; Pyrazoles; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Time Factors; Triazines	2021
Benefit of pazopanib in advanced gastrointestinal stromal tumours: results from a phase II trial (SSG XXI, PAGIST). ESMO open, 2021, Volume: 6, Issue:4 Topics: Gastrointestinal Stromal Tumors; Humans; Indazoles; Indoles; Pyrimidines; Pyrroles; Sulfonamides	2021
Avapritinib Versus Regorafenib in Locally Advanced Unresectable or Metastatic GI Stromal Tumor: A Randomized, Open-Label Phase III Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2021, 10-01, Volume: 39, Issue:28 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Asia; Australia; Disease Progression; Drug Administration Schedule; Europe; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Male; Middle Aged; Mutation; North America; Phenylurea Compounds; Progression-Free Survival; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrazoles; Pyridines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Time Factors; Triazines	2021
A Phase I Study of Binimetinib (MEK162) Combined with Pexidartinib (PLX3397) in Patients with Advanced Gastrointestinal Stromal Tumor. The oncologist, 2019, Volume: 24, Issue:10 Topics: Aged; Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Male; Maximum Tolerated Dose; Middle Aged; Pyrroles; Tissue Distribution	2019
Tumor response and clinical outcome in metastatic gastrointestinal stromal tumors under sunitinib therapy: comparison of RECIST, Choi and volumetric criteria. European journal of radiology, 2013, Volume: 82, Issue:6 Topics: Adolescent; Adult; Algorithms; Antineoplastic Agents; Disease-Free Survival; Female; Gastrointestinal Stromal Tumors; Humans; Imaging, Three-Dimensional; Indoles; Liver Neoplasms; Male; Middle Aged; Peritoneal Neoplasms; Pyrroles; Radiographic Image Interpretation, Computer-Assisted; Reproducibility of Results; Sensitivity and Specificity; Sunitinib; Survival Analysis; Tomography, X-Ray Computed; Treatment Outcome; Tumor Burden; Young Adult	2013
Phase II study of dovitinib in patients with metastatic and/or unresectable gastrointestinal stromal tumours after failure of imatinib and sunitinib. British journal of cancer, 2013, Oct-29, Volume: 109, Issue:9 Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Benzamides; Benzimidazoles; Disease Progression; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Piperazines; Prospective Studies; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Quinolones; Sunitinib	2013
Resumption of imatinib to control metastatic or unresectable gastrointestinal stromal tumours after failure of imatinib and sunitinib (RIGHT): a randomised, placebo-controlled, phase 3 trial. The Lancet. Oncology, 2013, Volume: 14, Issue:12 Topics: Aged; Antineoplastic Agents; Benzamides; Disease Progression; Disease-Free Survival; Double-Blind Method; Drug Administration Schedule; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Kaplan-Meier Estimate; Male; Middle Aged; Molecular Targeted Therapy; Piperazines; Proportional Hazards Models; Prospective Studies; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Republic of Korea; Sunitinib; Time Factors; Treatment Outcome	2013
A multicenter phase II study of pazopanib in patients with advanced gastrointestinal stromal tumors (GIST) following failure of at least imatinib and sunitinib. Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:1 Topics: Adult; Aged; Angiogenesis Inhibitors; Benzamides; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indazoles; Indoles; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Staging; Piperazines; Pyrimidines; Pyrroles; Sulfonamides; Sunitinib; Treatment Failure; Tumor Burden; Young Adult	2014
Comparison of performance of various tumour response criteria in assessment of regorafenib activity in advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib. European journal of cancer (Oxford, England : 1990), 2014, Volume: 50, Issue:5 Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Benzamides; Disease-Free Survival; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Outcome Assessment, Health Care; Phenylurea Compounds; Piperazines; Prospective Studies; Pyridines; Pyrimidines; Pyrroles; Retrospective Studies; Sunitinib; Tomography, X-Ray Computed; Treatment Failure; World Health Organization	2014
Health utility of patients with advanced gastrointestinal stromal tumors (GIST) after failure of imatinib and sunitinib: findings from GRID, a randomized, double-blind, placebo-controlled phase III study of regorafenib versus placebo. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2015, Volume: 18, Issue:3 Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Double-Blind Method; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Phenylurea Compounds; Placebo Effect; Pyridines; Pyrroles; Quality of Life; Sunitinib; Treatment Failure	2015
Masitinib in advanced gastrointestinal stromal tumor (GIST) after failure of imatinib: a randomized controlled open-label trial. Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzamides; Disease-Free Survival; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Piperazines; Piperidines; Prospective Studies; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyridines; Pyrimidines; Pyrroles; Sunitinib; Thiazoles; Treatment Failure	2014
Clinical outcomes of patients with advanced gastrointestinal stromal tumors: safety and efficacy in a worldwide treatment-use trial of sunitinib. Cancer, 2015, 05-01, Volume: 121, Issue:9 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Child; Diarrhea; Disease-Free Survival; Fatigue; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Indoles; Kaplan-Meier Estimate; Male; Middle Aged; Proportional Hazards Models; Pyrroles; Sarcoma; Sunitinib; Treatment Outcome; Young Adult	2015
Regorafenib for advanced gastrointestinal stromal tumors following imatinib and sunitinib treatment: a subgroup analysis evaluating Japanese patients in the phase III GRID trial. International journal of clinical oncology, 2015, Volume: 20, Issue:5 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Asian People; Double-Blind Method; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Middle Aged; Phenylurea Compounds; Pyridines; Pyrroles; Sunitinib; Survival Analysis; Young Adult	2015
Safety, efficacy and prognostic analyses of sunitinib in the post-marketing surveillance study of Japanese patients with gastrointestinal stromal tumor. Japanese journal of clinical oncology, 2015, Volume: 45, Issue:11 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Asian People; Disease-Free Survival; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Hand-Foot Syndrome; Humans; Incidence; Indoles; Japan; Male; Middle Aged; Neutropenia; Prognosis; Proportional Hazards Models; Pyrroles; Severity of Illness Index; Sunitinib; Thrombocytopenia; Treatment Outcome	2015
Correlation of KIT and PDGFRA mutational status with clinical benefit in patients with gastrointestinal stromal tumor treated with sunitinib in a worldwide treatment-use trial. BMC cancer, 2016, Jan-15, Volume: 16 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Gastrointestinal Stromal Tumors; Genotype; Humans; Indoles; Male; Middle Aged; Mutation; Prognosis; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sunitinib	2016
Pazopanib plus best supportive care versus best supportive care alone in advanced gastrointestinal stromal tumours resistant to imatinib and sunitinib (PAZOGIST): a randomised, multicentre, open-label phase 2 trial. The Lancet. Oncology, 2016, Volume: 17, Issue:5 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Female; France; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indazoles; Indoles; Male; Middle Aged; Neoplasm Staging; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Sulfonamides; Sunitinib; Treatment Outcome	2016
PK-PD modeling of individual lesion FDG-PET response to predict overall survival in patients with sunitinib-treated gastrointestinal stromal tumor. CPT: pharmacometrics & systems pharmacology, 2016, Volume: 5, Issue:4 Topics: Adult; Fluorodeoxyglucose F18; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Indoles; Models, Biological; Models, Statistical; Nonlinear Dynamics; Positron-Emission Tomography; Pyrroles; Radiopharmaceuticals; Sunitinib; Survival Analysis; Survival Rate; Treatment Outcome; Tumor Burden	2016
Long-term follow-up results of the multicenter phase II trial of regorafenib in patients with metastatic and/or unresectable GI stromal tumor after failure of standard tyrosine kinase inhibitor therapy. Annals of oncology : official journal of the European Society for Medical Oncology, 2016, Volume: 27, Issue:9 Topics: Adult; Aged; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Gastrointestinal Stromal Tumors; Genotype; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Mutation; Phenylurea Compounds; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyridines; Pyrroles; Sunitinib	2016
Efficacy and Safety of Regorafenib in Korean Patients with Advanced Gastrointestinal Stromal Tumor after Failure of Imatinib and Sunitinib: A Multicenter Study Based on the Management Access Program. Cancer research and treatment, 2017, Volume: 49, Issue:2 Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrroles; Retreatment; Sunitinib; Treatment Failure; Treatment Outcome	2017
Primary and secondary kinase genotypes correlate with the biological and clinical activity of sunitinib in imatinib-resistant gastrointestinal stromal tumor. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Nov-20, Volume: 26, Issue:33 Topics: Adult; Aged; Benzamides; Disease Progression; Disease-Free Survival; Drug Resistance, Neoplasm; Exons; Female; Gastrointestinal Stromal Tumors; Genotype; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Mutation; Phosphorylation; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sunitinib	2008
Early prediction of response to sunitinib after imatinib failure by 18F-fluorodeoxyglucose positron emission tomography in patients with gastrointestinal stromal tumor. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Jan-20, Volume: 27, Issue:3 Topics: Adult; Aged; Antineoplastic Agents; Benzamides; Disease Progression; Drug Resistance, Neoplasm; Female; Fluorodeoxyglucose F18; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Mutation; Piperazines; Positron-Emission Tomography; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Salvage Therapy; Sunitinib	2009
Cost-effectiveness analysis of sunitinib in patients with metastatic and/or unresectable gastrointestinal stroma tumours (GIST) after progression or intolerance with imatinib. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2008, Volume: 10, Issue:12 Topics: Algorithms; Antineoplastic Agents; Benzamides; Chemotherapy, Adjuvant; Cost-Benefit Analysis; Disease Progression; Double-Blind Method; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Health Resources; Humans; Imatinib Mesylate; Indoles; Markov Chains; Models, Econometric; Neoplasm Metastasis; Piperazines; Placebos; Pyrimidines; Pyrroles; Sunitinib; Survival Analysis; Treatment Failure	2008
Clinical evaluation of continuous daily dosing of sunitinib malate in patients with advanced gastrointestinal stromal tumour after imatinib failure. European journal of cancer (Oxford, England : 1990), 2009, Volume: 45, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Benzamides; Biomarkers, Tumor; Disease-Free Survival; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sunitinib; Survival Rate; Treatment Outcome; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Vascular Endothelial Growth Factor Receptor-3	2009
Phase I/II study of sunitinib malate in Japanese patients with gastrointestinal stromal tumor after failure of prior treatment with imatinib mesylate. Investigational new drugs, 2010, Volume: 28, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Asian People; Benzamides; Biomarkers, Tumor; Demography; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Japan; Male; Middle Aged; Neoplasm Proteins; Piperazines; Pyrimidines; Pyrroles; Solubility; Sunitinib; Treatment Failure; Young Adult	2010
Molecular target modulation, imaging, and clinical evaluation of gastrointestinal stromal tumor patients treated with sunitinib malate after imatinib failure. Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Sep-15, Volume: 15, Issue:18 Topics: Adult; Aged; Benzamides; Cell Proliferation; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorodeoxyglucose F18; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Piperazines; Positron-Emission Tomography; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sunitinib; Treatment Failure	2009
Hypertension induced by the tyrosine kinase inhibitor sunitinib is associated with increased circulating endothelin-1 levels. Hypertension (Dallas, Tex. : 1979), 2010, Volume: 56, Issue:4 Topics: Aged; Angiotensin II; Animals; Blood Pressure; Bradykinin; Carcinoma, Renal Cell; Cells, Cultured; Coronary Circulation; Endothelial Cells; Endothelin-1; Female; Gastrointestinal Stromal Tumors; Heart; Heart Rate; Humans; Hypertension; In Vitro Techniques; Indoles; Kidney Neoplasms; Male; Middle Aged; Pyrroles; Rats; Rats, Inbred WKY; Receptor Protein-Tyrosine Kinases; Renin; Sunitinib; Vascular Endothelial Growth Factor A	2010
Clinical efficacy and safety of sunitinib after imatinib failure in Japanese patients with gastrointestinal stromal tumor. Japanese journal of clinical oncology, 2011, Volume: 41, Issue:1 Topics: Adult; Aged; Antineoplastic Agents; Benzamides; Drug Administration Schedule; Drug Resistance, Neoplasm; Fatigue; Female; Gastrointestinal Stromal Tumors; Humans; Hyperammonemia; Imatinib Mesylate; Indoles; Japan; Kaplan-Meier Estimate; Magnetic Resonance Imaging; Male; Middle Aged; Piperazines; Portography; Pyrimidines; Pyrroles; Remission Induction; Retrospective Studies; Sunitinib; Tomography, X-Ray Computed; Treatment Failure; Treatment Outcome	2011
Phase 2 study of nilotinib as third-line therapy for patients with gastrointestinal stromal tumor. Cancer, 2011, Oct-15, Volume: 117, Issue:20 Topics: Adult; Aged; Antineoplastic Agents; Benzamides; Disease-Free Survival; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Kaplan-Meier Estimate; Male; Middle Aged; Mutation; Neoplasm Grading; Neoplasm Staging; Piperazines; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Salvage Therapy; Sunitinib; Time Factors; Treatment Outcome	2011
A USA registry of gastrointestinal stromal tumor patients: changes in practice over time and differences between community and academic practices. Annals of oncology : official journal of the European Society for Medical Oncology, 2011, Volume: 22, Issue:11 Topics: Academic Medical Centers; Adolescent; Adult; Aged; Aged, 80 and over; Benzamides; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Hospitals, Community; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Molecular Targeted Therapy; Piperazines; Practice Patterns, Physicians'; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Registries; Sunitinib; United States; Young Adult	2011
Vatalanib for metastatic gastrointestinal stromal tumour (GIST) resistant to imatinib: final results of a phase II study. British journal of cancer, 2011, May-24, Volume: 104, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzamides; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Phthalazines; Piperazines; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Pyrroles; Sunitinib	2011
Evaluation of nilotinib in advanced GIST previously treated with imatinib and sunitinib. Cancer chemotherapy and pharmacology, 2012, Volume: 69, Issue:4 Topics: Aged; Benzamides; Disease-Free Survival; Drug Resistance, Neoplasm; Exons; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Mutation; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sunitinib	2012
Phase III study of nilotinib versus best supportive care with or without a TKI in patients with gastrointestinal stromal tumors resistant to or intolerant of imatinib and sunitinib. Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:7 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzamides; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Kaplan-Meier Estimate; Male; Middle Aged; Palliative Care; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Sunitinib; Treatment Outcome; Young Adult	2012
Efficacy and safety of regorafenib in patients with metastatic and/or unresectable GI stromal tumor after failure of imatinib and sunitinib: a multicenter phase II trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jul-01, Volume: 30, Issue:19 Topics: Adult; Aged; Antineoplastic Agents; Benzamides; Disease-Free Survival; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Neoplasm Metastasis; Phenylurea Compounds; Piperazines; Pyridines; Pyrimidines; Pyrroles; Sunitinib; Treatment Outcome	2012
Complete longitudinal analyses of the randomized, placebo-controlled, phase III trial of sunitinib in patients with gastrointestinal stromal tumor following imatinib failure. Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Jun-01, Volume: 18, Issue:11 Topics: Adult; Aged; Benzamides; Biomarkers, Tumor; Cross-Over Studies; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Neovascularization, Pathologic; Piperazines; Placebos; Pyrimidines; Pyrroles; Retreatment; Sunitinib; Survival Analysis; Young Adult	2012
Hypertension as a potential biomarker of efficacy in patients with gastrointestinal stromal tumor treated with sunitinib. Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:12 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antineoplastic Agents; Benzamides; Biomarkers, Tumor; Blood Pressure; Carcinoma, Renal Cell; Child; Disease-Free Survival; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Hypertension; Imatinib Mesylate; Indoles; Kidney Neoplasms; Male; Middle Aged; Piperazines; Proportional Hazards Models; Prospective Studies; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Signal Transduction; Sunitinib; Treatment Outcome; Vascular Endothelial Growth Factor Receptor-2; Vascular Endothelial Growth Factors; Young Adult	2012
Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib (GRID): an international, multicentre, randomised, placebo-controlled, phase 3 trial. Lancet (London, England), 2013, Jan-26, Volume: 381, Issue:9863 Topics: Aged; Antineoplastic Agents; Benzamides; Double-Blind Method; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Phenylurea Compounds; Piperazines; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Pyrroles; Sunitinib; Survival Rate; Treatment Failure	2013
Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial. Lancet (London, England), 2006, Oct-14, Volume: 368, Issue:9544 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzamides; Double-Blind Method; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Sunitinib; Survival Analysis; Treatment Outcome	2006
Hypothyroidism after sunitinib treatment for patients with gastrointestinal stromal tumors. Annals of internal medicine, 2006, Nov-07, Volume: 145, Issue:9 Topics: Adult; Antineoplastic Agents; Drug Administration Schedule; Female; Gastrointestinal Stromal Tumors; Humans; Hypothyroidism; Indoles; Prospective Studies; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Pyrroles; Sunitinib; Thyroiditis; Thyrotropin	2006
Brostallicin, an agent with potential activity in metastatic soft tissue sarcoma: a phase II study from the European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group. European journal of cancer (Oxford, England : 1990), 2007, Volume: 43, Issue:2 Topics: Adult; Aged; Antineoplastic Agents; Disease Progression; Female; Gastrointestinal Stromal Tumors; Guanidines; Humans; Infusions, Intravenous; Male; Middle Aged; Pyrroles; Sarcoma; Soft Tissue Neoplasms; Survival Analysis; Treatment Outcome	2007
Blood-based biomarkers of SU11248 activity and clinical outcome in patients with metastatic imatinib-resistant gastrointestinal stromal tumor. Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, May-01, Volume: 13, Issue:9 Topics: Adult; Antineoplastic Agents; Benzamides; Biomarkers; Endothelial Cells; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Monocytes; Piperazines; Pyrimidines; Pyrroles; Sunitinib; Treatment Outcome; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2	2007
A novel tyrosine-kinase selective inhibitor, sunitinib, induces transient hypothyroidism by blocking iodine uptake. The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:9 Topics: Adult; Aged; Biological Transport; Female; Gastrointestinal Stromal Tumors; Humans; Hypothyroidism; Indoles; Iodine; Iodine Radioisotopes; Male; Middle Aged; Protein Kinase Inhibitors; Pyrroles; Sunitinib; Thyrotropin	2007
Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma and various other solid tumors. The Journal of steroid biochemistry and molecular biology, 2008, Volume: 108, Issue:3-5 Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Renal Cell; Female; Gastrointestinal Stromal Tumors; Humans; Indoles; Kidney Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neuroendocrine Tumors; Pyrroles; Receptors, Platelet-Derived Growth Factor; Receptors, Vascular Endothelial Growth Factor; Sunitinib	2008
The challenge of conducting pharmacoeconomic evaluations in oncology using crossover trials: the example of sunitinib for gastrointestinal stromal tumour. European journal of cancer (Oxford, England : 1990), 2008, Volume: 44, Issue:7 Topics: Antineoplastic Agents; Benzamides; Canada; Cost-Benefit Analysis; Cross-Over Studies; Disease-Free Survival; Drug Costs; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Markov Chains; Piperazines; Pyrimidines; Pyrroles; Quality-Adjusted Life Years; Sunitinib	2008

Other Studies

197 other study(ies) available for pyrroles and Gastrointestinal Stromal Tumors

Article	Year
Efficacy and safety of regorafenib in Japanese patients with advanced gastrointestinal stromal tumors. International journal of clinical oncology, 2022, Volume: 27, Issue:7 Topics: Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Indoles; Japan; Neoplasm Recurrence, Local; Phenylurea Compounds; Pyridines; Pyrroles; Retrospective Studies	2022
Differential activity of avapritinib in patients with metastases from mucosal melanoma and thymic carcinoma harbouring KIT exon 17 mutations: Initial experience from a Compassionate Use Program in Italy. European journal of cancer (Oxford, England : 1990), 2022, Volume: 172 Topics: Antineoplastic Agents; Compassionate Use Trials; Exons; Gastrointestinal Stromal Tumors; Humans; Melanoma; Mutation; Precision Medicine; Proto-Oncogene Proteins c-kit; Pyrazoles; Pyrroles; Thymoma; Thymus Neoplasms; Triazines	2022
Sunitinib-Induced Congestive Heart Failure in a Patient with Gastrointestinal Stromal Tumor. Archives of Iranian medicine, 2022, 06-01, Volume: 25, Issue:6 Topics: Aged; Antineoplastic Agents; Female; Gastrointestinal Stromal Tumors; Heart Failure; Humans; Indoles; Pyrroles; Sunitinib	2022
Sunitinib therapy for imatinib-resistant and/or intolerant gastrointestinal stromal tumors: comparison of safety and efficacy between standard and reduced dosage regimens. Japanese journal of clinical oncology, 2023, Mar-30, Volume: 53, Issue:4 Topics: Antineoplastic Agents; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Pyrimidines; Pyrroles; Retrospective Studies; Sunitinib; Treatment Outcome	2023
GIST: Molecular Profiling Suggests 2nd Therapy. Cancer discovery, 2023, 03-01, Volume: 13, Issue:3 Topics: Antineoplastic Agents; Disease-Free Survival; Gastrointestinal Stromal Tumors; Humans; Indoles; Mutation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrroles; Sunitinib	2023
Management of a feline gastric stromal cell tumour with toceranib phosphate: a case study. Australian veterinary journal, 2020, Volume: 98, Issue:5 Topics: Animals; Cat Diseases; Cats; Female; Gastrointestinal Stromal Tumors; Indoles; Pyrroles; Stromal Cells	2020
Physiologically Based Pharmacokinetic Modeling and Simulation of Sunitinib in Pediatrics. The AAPS journal, 2020, 01-23, Volume: 22, Issue:2 Topics: Administration, Oral; Adolescent; Age Factors; Antineoplastic Agents; Child; Child, Preschool; Clinical Trials as Topic; Computer Simulation; Cytochrome P-450 CYP3A; Drug Administration Schedule; Drug Dosage Calculations; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Indoles; Models, Biological; Protein Kinase Inhibitors; Pyrroles; Sunitinib; Young Adult	2020
First Targeted Therapy for Rare Form of GI Stromal Tumors. The American journal of nursing, 2020, Volume: 120, Issue:5 Topics: Gastrointestinal Stromal Tumors; Humans; Mutation; Pyrazoles; Pyrroles; Rare Diseases; Triazines	2020
The relationship between sunitinib exposure and both efficacy and toxicity in real-world patients with renal cell carcinoma and gastrointestinal stromal tumour. British journal of clinical pharmacology, 2021, Volume: 87, Issue:2 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Gastrointestinal Stromal Tumors; Humans; Indoles; Kidney Neoplasms; Pyrroles; Retrospective Studies; Sunitinib; Treatment Outcome	2021
[Updates and interpretations of the NCCN Clinical Practice Guidelines (2019 6th version) on gastrointestinal stromal tumor]. Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2020, Sep-25, Volume: 23, Issue:9 Topics: Antineoplastic Agents; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Molecular Targeted Therapy; Practice Guidelines as Topic; Protein Kinase Inhibitors; Pyrazoles; Pyrroles; Triazines	2020
[Current status and progress in novel drug research for gastrointestinal stromal tumors]. Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2020, Sep-25, Volume: 23, Issue:9 Topics: Antineoplastic Agents; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Naphthyridines; Protein Kinase Inhibitors; Pyrazoles; Pyrroles; Triazines; Urea	2020
Financial Implications of Avapritinib for Treatment of Unresectable Gastrointestinal Stromal Tumors in Patients With a PDGFRA Exon 18 Variant or After 3 Previous Therapies in a Hypothetical US Health Plan. JAMA network open, 2020, 11-02, Volume: 3, Issue:11 Topics: Antineoplastic Agents; Budgets; Cost-Benefit Analysis; Formularies as Topic; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indazoles; Managed Care Programs; Medicaid; Medicare; Molecular Diagnostic Techniques; Phenylurea Compounds; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sulfonamides; Sunitinib; Treatment Failure; Triazines; United States	2020
Identification of Wee1 as a target in combination with avapritinib for gastrointestinal stromal tumor treatment. JCI insight, 2021, 01-25, Volume: 6, Issue:2 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Female; Gastrointestinal Stromal Tumors; Humans; Male; Mice; Mice, SCID; Mutation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-kit; Pyrazoles; Pyrimidinones; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Signal Transduction; Triazines; Xenograft Model Antitumor Assays	2021
Avapritinib in Patients With Advanced Gastrointestinal Stromal Tumors Following at Least Three Prior Lines of Therapy. The oncologist, 2021, Volume: 26, Issue:4 Topics: Antineoplastic Agents; Gastrointestinal Stromal Tumors; Humans; Mutation; Proto-Oncogene Proteins c-kit; Pyrazoles; Pyrroles; Triazines	2021
Avapritinib (Ayvakit) for GIST. The Medical letter on drugs and therapeutics, 2021, 02-08, Volume: 63, Issue:1617 Topics: Antineoplastic Agents; Clinical Trials as Topic; Gastrointestinal Stromal Tumors; Humans; Protein Kinase Inhibitors; Pyrazoles; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Triazines	2021
Clinical efficacy comparison of avapritinib with other tyrosine kinase inhibitors in gastrointestinal stromal tumors with PDGFRA D842V mutation: a retrospective analysis of clinical trial and real-world data. BMC cancer, 2021, Mar-19, Volume: 21, Issue:1 Topics: Clinical Trials, Phase I as Topic; Female; Gastrointestinal Stromal Tumors; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Progression-Free Survival; Protein Kinase Inhibitors; Pyrazoles; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Retrospective Studies; Triazines	2021
Preseptal cellulitis, intraocular inflammatory reaction and corneal persistent epithelial defect as side effects of avapritinib. Anti-cancer drugs, 2021, 11-01, Volume: 32, Issue:10 Topics: Aged; Antineoplastic Agents; Cellulitis; Epithelium, Corneal; Eye Diseases; Female; Gastrointestinal Stromal Tumors; Humans; Inflammation; Neoplasm Metastasis; Neoplasm Staging; Pyrazoles; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Triazines	2021
Avapritinib in unresectable or metastatic gastrointestinal stromal tumor with PDGFRA exon 18 mutation: safety and efficacy. Expert review of anticancer therapy, 2021, Volume: 21, Issue:10 Topics: Antineoplastic Agents; Exons; Gastrointestinal Stromal Tumors; Humans; Mutation; Precision Medicine; Proto-Oncogene Proteins c-kit; Pyrazoles; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Triazines	2021
Gastrointestinal stromal tumor of the stomach with axillary lymph node metastasis: A case report. World journal of gastroenterology, 2017, Mar-07, Volume: 23, Issue:9 Topics: Aged; Axilla; Fatal Outcome; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Lymph Nodes; Lymphatic Metastasis; Male; Neoplasm Metastasis; Phenylurea Compounds; Positron-Emission Tomography; Pyridines; Pyrroles; Stomach Neoplasms; Sunitinib; Tomography, X-Ray Computed	2017
Clinical benefit of sunitinib in gastrointestinal stromal tumors with different exon 11 mutation genotypes. Future oncology (London, England), 2017, Volume: 13, Issue:23 Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents; Combined Modality Therapy; Disease Progression; Drug Substitution; Exons; Female; Gastrointestinal Stromal Tumors; Genotype; Humans; Indoles; Kaplan-Meier Estimate; Male; Middle Aged; Mutation; Neoplasm Recurrence, Local; Prognosis; Pyrroles; Sunitinib; Treatment Failure; Treatment Outcome	2017
Jejunal Gastrointestinal Stromal Tumor. Mayo Clinic proceedings, 2017, Volume: 92, Issue:10 Topics: Aged; Antineoplastic Agents; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Indoles; Jejunal Neoplasms; Jejunum; Male; Pyrroles; Sunitinib	2017
Treatment of gastrointestinal stromal tumours in paediatric and young adult patients with sunitinib: a multicentre case series. BMC cancer, 2017, Nov-06, Volume: 17, Issue:1 Topics: Adolescent; Antineoplastic Agents; Child; Europe; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Proto-Oncogene Proteins c-kit; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Retrospective Studies; Sunitinib; Survival Analysis; Treatment Outcome; United States; Young Adult	2017
[Treatment of Regorafenib in Patients with Metastatic or Unresectable Gastrointestinal Stromal Tumor after Failure of Imatinib and Sunitinib]. Gan to kagaku ryoho. Cancer & chemotherapy, 2018, Volume: 45, Issue:1 Topics: Adult; Aged; Antineoplastic Agents; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Phenylurea Compounds; Pyridines; Pyrroles; Sunitinib	2018
[A Long-Term Survivor Who Are Responding to Sunitinib Treatment for Recurrent Imatinib-Resistant Gastrointestinal Stromal Tumor(GIST)of the Stomach]. Gan to kagaku ryoho. Cancer & chemotherapy, 2017, Volume: 44, Issue:12 Topics: Antineoplastic Agents; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Pyrroles; Recurrence; Stomach Neoplasms; Sunitinib; Time Factors	2017
[A Case of Long-Term Survival of Metastatic and Recurrent Duodenal Gastrointestinal Stromal Tumor Treated with Multimodality Managements]. Gan to kagaku ryoho. Cancer & chemotherapy, 2018, Volume: 45, Issue:3 Topics: Antineoplastic Agents; Combined Modality Therapy; Drug Resistance, Neoplasm; Duodenal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Pyrroles; Sunitinib	2018
MRI in predicting the response of gastrointestinal stromal tumor to targeted therapy: a patient-based multi-parameter study. BMC cancer, 2018, Aug-13, Volume: 18, Issue:1 Topics: Adult; Aged; Diffusion Magnetic Resonance Imaging; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Pyrroles; Sunitinib; Treatment Outcome	2018
Sunitinib-induced acute severe hypothyroidism in a case of metastatic gastrointestinal stromal tumor: A case report. Journal of cancer research and therapeutics, 2018, Volume: 14, Issue:Supplement Topics: Aged; Gastrointestinal Stromal Tumors; Humans; Hypothyroidism; Indoles; Male; Pyrroles; Sunitinib; Thyrotropin	2018
Retrospective evaluation of toceranib phosphate (Palladia®) use in the treatment of gastrointestinal stromal tumors of dogs. Journal of veterinary internal medicine, 2018, Volume: 32, Issue:6 Topics: Animals; Antineoplastic Agents; Dog Diseases; Dogs; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Indoles; Male; Mitotic Index; Prognosis; Progression-Free Survival; Pyrroles; Retrospective Studies	2018
Ethyl-2-amino-pyrrole-3-carboxylates are active against imatinib-resistant gastrointestinal stromal tumors in vitro and in vivo. Anti-cancer drugs, 2019, Volume: 30, Issue:5 Topics: Animals; Antineoplastic Agents; Apoptosis; Carboxylic Acids; Cell Proliferation; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; In Vitro Techniques; Mice; Mice, Nude; Pyrroles; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2019
Real-World Evidence of Patient Outcome Following Treatment of Advanced Gastrointestinal Stromal Tumor (GIST) with Imatinib, Sunitinib, and Sorafenib in Publicly Funded Health Care in Poland. Medical science monitor : international medical journal of experimental and clinical research, 2019, May-23, Volume: 25 Topics: Adult; Aged; Antineoplastic Agents; Benzamides; Disease-Free Survival; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Poland; Protein Kinase Inhibitors; Public Health Practice; Pyrroles; Sorafenib; Sunitinib; Treatment Outcome	2019
Secondary mutations of c-KIT contribute to acquired resistance to imatinib and decrease efficacy of sunitinib in Chinese patients with gastrointestinal stromal tumors. Medical oncology (Northwood, London, England), 2013, Volume: 30, Issue:2 Topics: Adult; Aged; Amino Acid Sequence; Antineoplastic Agents; Asian People; Benzamides; Drug Resistance, Neoplasm; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Molecular Sequence Data; Mutation; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Retrospective Studies; Sunitinib; Survival Rate; Treatment Outcome; Young Adult	2013
Gastrointestinal stromal tumors: diagnosis, therapy and follow-up care in Austria. Wiener medizinische Wochenschrift (1946), 2013, Volume: 163, Issue:5-6 Topics: Adult; Aftercare; Austria; Benzamides; Biopsy; Child; Combined Modality Therapy; Cooperative Behavior; Diagnosis, Differential; Diagnostic Imaging; Disease Progression; Endoscopy, Gastrointestinal; Follow-Up Studies; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Gastrointestinal Tract; Humans; Imatinib Mesylate; Indoles; Interdisciplinary Communication; Mitotic Index; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasms, Multiple Primary; Nomograms; Palliative Care; Phenylurea Compounds; Piperazines; Proto-Oncogene Proteins c-kit; Pyridines; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Risk Assessment; Sunitinib	2013
[Gastrointestinal stromal tumor (GIST)--tyrosine kinase inhibitors]. Nihon rinsho. Japanese journal of clinical medicine, 2012, Volume: 70 Suppl 8 Topics: Antineoplastic Agents; Benzamides; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Sunitinib	2012
[Efficacy and safety of sunitinib on patients with imatinib-resistant gastrointestinal stromal tumor]. Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2013, Volume: 16, Issue:3 Topics: Adult; Aged; Benzamides; Drug Resistance, Neoplasm; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Piperazines; Pyrimidines; Pyrroles; Retrospective Studies; Sunitinib; Treatment Outcome	2013
Transient sunitinib resistance in gastrointestinal stromal tumors. The New England journal of medicine, 2013, May-23, Volume: 368, Issue:21 Topics: Antineoplastic Agents; Disease Progression; Drug Resistance, Neoplasm; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Indoles; Male; Middle Aged; Pyrroles; Sunitinib	2013
Selecting tyrosine kinase inhibitors for gastrointestinal stromal tumor with secondary KIT activation-loop domain mutations. PloS one, 2013, Volume: 8, Issue:6 Topics: Amino Acid Motifs; Animals; Antineoplastic Agents; Benzamides; Chlorocebus aethiops; COS Cells; Dasatinib; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Hydrogen Bonding; Imatinib Mesylate; Indoles; Molecular Docking Simulation; Mutation, Missense; Piperazines; Protein Binding; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sunitinib; Thiazoles	2013
Value of pharmacokinetic studies for patients with gastrointestinal stromal tumors. Future oncology (London, England), 2013, Volume: 9, Issue:11 Topics: Antineoplastic Agents; Benzamides; Dose-Response Relationship, Drug; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Molecular Targeted Therapy; Piperazines; Pyrimidines; Pyrroles; Sunitinib	2013
Sunitinib-induced reversible purpuric rash in a patient with gastrointestinal stromal tumor. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2014, Volume: 20, Issue:4 Topics: Aged; Antineoplastic Agents; Exanthema; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Protein Kinase Inhibitors; Pyrroles; Sunitinib	2014
Sunitinib as first-line neoadjuvant therapy in two patients with rectal stromal tumors. Future oncology (London, England), 2013, Volume: 9, Issue:11 Topics: Angiogenesis Inhibitors; Gastrointestinal Stromal Tumors; Humans; Indoles; Male; Middle Aged; Neoadjuvant Therapy; Pyrroles; Radiography; Rectal Neoplasms; Sunitinib; Treatment Outcome	2013
[A long-term control of gastrointestinal stromal tumor with sunitinib]. Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:9 Topics: Aged; Antineoplastic Agents; Female; Gastrointestinal Stromal Tumors; Hepatectomy; Humans; Indoles; Jejunal Neoplasms; Jejunostomy; Liver Neoplasms; Pyrroles; Sunitinib; Time Factors	2013
Rechallenge of drugs in the era of targeted therapy. The Lancet. Oncology, 2013, Volume: 14, Issue:12 Topics: Antineoplastic Agents; Benzamides; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Sunitinib	2013
Flumatinib, a selective inhibitor of BCR-ABL/PDGFR/KIT, effectively overcomes drug resistance of certain KIT mutants. Cancer science, 2014, Volume: 105, Issue:1 Topics: Aminopyridines; Animals; Antineoplastic Agents; Benzamides; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Fusion Proteins, bcr-abl; Gastrointestinal Stromal Tumors; Imatinib Mesylate; Indoles; Interleukin-3; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Piperazines; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Random Allocation; Sunitinib	2014
Sunitinib treatment for multiple brain metastases from jejunal gastrointestinal stromal tumor: case report. Neurologia medico-chirurgica, 2014, Volume: 54, Issue:8 Topics: Aged; Angiogenesis Inhibitors; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Gastrointestinal Stromal Tumors; Humans; Indoles; Jejunal Neoplasms; Magnetic Resonance Imaging; Male; Pyrroles; Radiosurgery; Sunitinib; Tomography, X-Ray Computed	2014
[A case of imatinib-resistant gastrointestinal stromal tumor treated with low-dose sunitinib]. Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:13 Topics: Aged, 80 and over; Antineoplastic Agents; Benzamides; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Intestinal Neoplasms; Intestine, Small; Male; Peritoneal Neoplasms; Piperazines; Pyrimidines; Pyrroles; Recurrence; Salvage Therapy; Sunitinib	2013
Rechallenge with imatinib in GIST: is more always RIGHT? The Lancet. Oncology, 2014, Volume: 15, Issue:1 Topics: Antineoplastic Agents; Benzamides; Female; Gastrointestinal Stromal Tumors; Humans; Indoles; Male; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles	2014
Increased KIT inhibition enhances therapeutic efficacy in gastrointestinal stromal tumor. Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, May-01, Volume: 20, Issue:9 Topics: Aminopyridines; Animals; Antineoplastic Agents; Benzamides; Biopsy; Cell Survival; Disease Models, Animal; Drug Evaluation, Preclinical; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Inhibitory Concentration 50; Mice, Knockout; Molecular Targeted Therapy; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, Macrophage Colony-Stimulating Factor; Tumor Burden	2014
[Treatment strategy for recurrent and metastatic gastrointestinal stromal tumors]. Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2014, Volume: 17, Issue:4 Topics: Benzamides; Disease-Free Survival; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Hepatectomy; Humans; Imatinib Mesylate; Indazoles; Indoles; Liver Neoplasms; Phenylurea Compounds; Piperazines; Pyridines; Pyrimidines; Pyrroles; Recurrence; Sulfonamides; Sunitinib	2014
[Drug resistance mechanism and new therapy strategy progression in targeted treatment of gastrointestinal stromal tumors]. Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2014, Volume: 17, Issue:4 Topics: Antineoplastic Agents; Benzamides; Disease Progression; Drug Resistance, Neoplasm; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Quality of Life; Receptor, Platelet-Derived Growth Factor alpha; Sunitinib	2014
Sunitinib-induced pseudoporphyria. Journal of the European Academy of Dermatology and Venereology : JEADV, 2015, Volume: 29, Issue:9 Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Biopsy; Diagnosis, Differential; Drug Eruptions; Gastrointestinal Stromal Tumors; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Porphyrias; Pyrroles; Sunitinib	2015
Gastrointestinal stromal tumors, version 2.2014. Journal of the National Comprehensive Cancer Network : JNCCN, 2014, Volume: 12, Issue:6 Topics: Benzamides; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sunitinib	2014
Effect of gastrointestinal resection on sunitinib exposure in patients with GIST. BMC cancer, 2014, Aug-08, Volume: 14 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Clinical Trials as Topic; Female; Gastrectomy; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Indoles; Male; Middle Aged; Pyrroles; Sunitinib; Young Adult	2014
Imatinib escalation or sunitinib treatment after first-line imatinib in metastatic gastrointestinal stromal tumor patients. Anticancer research, 2014, Volume: 34, Issue:9 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Benzamides; Drug Substitution; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Mutation; Neoplasm Metastasis; Piperazines; Prognosis; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Retreatment; Sunitinib; Treatment Outcome; Young Adult	2014
Ponatinib inhibits polyclonal drug-resistant KIT oncoproteins and shows therapeutic potential in heavily pretreated gastrointestinal stromal tumor (GIST) patients. Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Nov-15, Volume: 20, Issue:22 Topics: Animals; Antineoplastic Agents; Benzamides; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Exons; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Imidazoles; Indoles; Inhibitory Concentration 50; Models, Molecular; Molecular Conformation; Mutation; Neoplasm Recurrence, Local; Piperazines; Protein Binding; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyridazines; Pyrimidines; Pyrroles; Sunitinib; Tomography, X-Ray Computed; Tumor Burden; Xenograft Model Antitumor Assays	2014
Hepatic artery embolization for liver metastasis of gastrointestinal stromal tumor following imatinib and sunitinib therapy. Journal of gastrointestinal cancer, 2014, Volume: 45, Issue:4 Topics: Adult; Aged; Benzamides; Disease-Free Survival; Drug Resistance, Neoplasm; Embolization, Therapeutic; Female; Gastrointestinal Stromal Tumors; Hepatic Artery; Humans; Imatinib Mesylate; Indoles; Liver Neoplasms; Male; Middle Aged; Piperazines; Prognosis; Pyrimidines; Pyrroles; Retrospective Studies; Sunitinib; Survival Analysis; Treatment Outcome	2014
[The importance of mutational status in prognosis and therapy of GIST]. Recenti progressi in medicina, 2015, Volume: 106, Issue:1 Topics: Antineoplastic Agents; Benzamides; Biomarkers, Tumor; Disease Progression; DNA Mutational Analysis; Drug Resistance, Neoplasm; Exons; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Genotype; Humans; Imatinib Mesylate; Indoles; Molecular Targeted Therapy; Mutation; Neoplasm Staging; Phenylurea Compounds; Piperazines; Predictive Value of Tests; Prognosis; Proto-Oncogene Proteins c-kit; Pyridines; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sensitivity and Specificity; Sunitinib	2015
[A case of recurrent duodenal gastrointestinal stromal tumor resistant to imatinib and sunitinib, successfully treated with regorafenib]. Gan to kagaku ryoho. Cancer & chemotherapy, 2014, Volume: 41, Issue:12 Topics: Antineoplastic Combined Chemotherapy Protocols; Benzamides; Drug Resistance, Neoplasm; Duodenal Neoplasms; Fatal Outcome; Female; Gastrointestinal Stromal Tumors; Hepatectomy; Humans; Imatinib Mesylate; Indoles; Liver Neoplasms; Middle Aged; Phenylurea Compounds; Piperazines; Pyridines; Pyrimidines; Pyrroles; Recurrence; Sunitinib; Treatment Outcome	2014
[A case of small intestinal gastrointestinal stromal tumor (GIST) with peritoneal dissemination, treated effectively with molecular target drug after operation]. Gan to kagaku ryoho. Cancer & chemotherapy, 2014, Volume: 41, Issue:12 Topics: Antineoplastic Agents; Benzamides; Chemotherapy, Adjuvant; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Intestinal Neoplasms; Intestine, Small; Male; Middle Aged; Molecular Targeted Therapy; Peritoneal Neoplasms; Piperazines; Pyrimidines; Pyrroles; Sunitinib	2014
Primary gastrointestinal stromal tumor of the liver treated with sequential therapy. World journal of gastroenterology, 2015, Feb-28, Volume: 21, Issue:8 Topics: Aged; Antineoplastic Agents; Benzamides; Biomarkers, Tumor; Biopsy; Chemotherapy, Adjuvant; DNA Mutational Analysis; Drug Substitution; Female; Gastrointestinal Stromal Tumors; Hepatectomy; Humans; Imatinib Mesylate; Immunohistochemistry; Indoles; Liver Neoplasms; Mutation; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Sunitinib; Time Factors; Tomography, X-Ray Computed; Treatment Outcome	2015
Long term experience of patients with unresectable or metastatic KIT positive gastrointestinal stromal tumours. Bratislavske lekarske listy, 2015, Volume: 116, Issue:4 Topics: Adult; Aged; Antineoplastic Agents; Benzamides; Czech Republic; Disease-Free Survival; Female; Follow-Up Studies; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Piperazines; Pyrimidines; Pyrroles; Retrospective Studies; Sunitinib; Survival Rate; Time Factors	2015
Pharmacological Inhibition of KIT Activates MET Signaling in Gastrointestinal Stromal Tumors. Cancer research, 2015, May-15, Volume: 75, Issue:10 Topics: Anilides; Animals; Antineoplastic Agents; Benzamides; Cell Line, Tumor; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Inhibitory Concentration 50; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, SCID; Piperazines; Proto-Oncogene Proteins c-kit; Proto-Oncogene Proteins c-met; Pyridines; Pyrimidines; Pyrroles; Signal Transduction; Sunitinib; Tumor Burden; Xenograft Model Antitumor Assays	2015
[Clinical management of advanced gastrointestinal stromal tumors after failure of at least both imatinib and sunitinib targeted therapy]. Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2015, Volume: 18, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Pyrroles; Sunitinib	2015
Imatinib dose escalation versus sunitinib as a second line treatment in KIT exon 11 mutated GIST: a retrospective analysis. Oncotarget, 2016, 10-25, Volume: 7, Issue:43 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Disease Progression; Disease-Free Survival; Dose-Response Relationship, Drug; Exons; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Mutation; Proto-Oncogene Proteins c-kit; Pyrroles; Retrospective Studies; Sunitinib; Time Factors	2016
Drug therapy: Preclinical oncology - reporting transparency needed. Nature reviews. Clinical oncology, 2016, Volume: 13, Issue:1 Topics: Animals; Antineoplastic Agents; Carcinoma, Neuroendocrine; Carcinoma, Renal Cell; Clinical Trials as Topic; Evidence-Based Medicine; Gastrointestinal Stromal Tumors; Humans; Indoles; Kidney Neoplasms; Medical Oncology; Meta-Analysis as Topic; Neoplasms; Pancreatic Neoplasms; Practice Guidelines as Topic; Pyrroles; Research Design; Research Report; Stomach Neoplasms; Sunitinib; Treatment Outcome	2016
The novel pyrrolo-1,5-benzoxazepine, PBOX-15, synergistically enhances the apoptotic efficacy of imatinib in gastrointestinal stromal tumours; suggested mechanism of action of PBOX-15. Investigational new drugs, 2016, Volume: 34, Issue:2 Topics: Apoptosis; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Chaperonins; Down-Regulation; Drug Resistance, Neoplasm; Drug Synergism; Flow Cytometry; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Myeloid Cell Leukemia Sequence 1 Protein; Oxazepines; Proto-Oncogene Proteins c-kit; Pyrroles; Signal Transduction; Treatment Outcome	2016
[A case of a gastrointestinal stromal tumor of the rectum effectively treated with continuously-administered regorafenib after failure of imatinib and sunitinib]. Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2016, Volume: 113, Issue:4 Topics: Antineoplastic Agents; Drug Resistance, Neoplasm; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Phenylurea Compounds; Pyridines; Pyrroles; Rectal Neoplasms; Sunitinib	2016
Ethyl-2-amino-pyrrole-3-carboxylates are novel potent anticancer agents that affect tubulin polymerization, induce G2/M cell-cycle arrest, and effectively inhibit soft tissue cancer cell growth in vitro. Anti-cancer drugs, 2016, Volume: 27, Issue:7 Topics: Antineoplastic Agents; Bone Neoplasms; Carboxylic Acids; Cell Death; Cell Growth Processes; Cell Line, Tumor; G2 Phase Cell Cycle Checkpoints; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Leiomyosarcoma; M Phase Cell Cycle Checkpoints; Osteosarcoma; Pyrroles; Rhabdomyosarcoma; Sarcoma; Sarcoma, Ewing; Tubulin; Tubulin Modulators	2016
Monte Carlo simulations of the clinical benefits from therapeutic drug monitoring of sunitinib in patients with gastrointestinal stromal tumours. Cancer chemotherapy and pharmacology, 2016, Volume: 78, Issue:1 Topics: Antineoplastic Agents; Computer Simulation; Disease Progression; Dose-Response Relationship, Drug; Drug Monitoring; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Indoles; Models, Biological; Monte Carlo Method; Pyrroles; Sunitinib; Time Factors; Treatment Outcome	2016
Sunitinib-associated Pancreatic Atrophy in Patients with Gastrointestinal Stromal Tumor: A Toxicity with Prognostic Implications Detected at Imaging. Radiology, 2016, Volume: 281, Issue:1 Topics: Adult; Aged; Antineoplastic Agents; Atrophy; Case-Control Studies; Female; Gastrointestinal Stromal Tumors; Humans; Indoles; Male; Middle Aged; Pancreas; Prognosis; Pyrroles; Retrospective Studies; Sunitinib; Tomography, X-Ray Computed	2016
Detection and Quantification of KIT Mutations in ctDNA by Plasma Safe-SeqS. Advances in experimental medicine and biology, 2016, Volume: 924 Topics: Antineoplastic Agents; DNA Mutational Analysis; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Outcome Assessment, Health Care; Phenylurea Compounds; Proto-Oncogene Proteins c-kit; Pyridines; Pyrroles; Reproducibility of Results; Sunitinib	2016
Computed tomography features and predictive findings of ruptured gastrointestinal stromal tumours. European radiology, 2017, Volume: 27, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Ascites; Disease Progression; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Hematoma; Hemoperitoneum; Humans; Imatinib Mesylate; Indoles; Intestine, Small; Male; Middle Aged; Necrosis; Peritonitis; Pyrroles; Rupture, Spontaneous; Sensitivity and Specificity; Sunitinib; Tomography, X-Ray Computed; Young Adult	2017
An exploratory association of polymorphisms in angiogenesis-related genes with susceptibility, clinical response and toxicity in gastrointestinal stromal tumors receiving sunitinib after imatinib failure. Angiogenesis, 2017, Volume: 20, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Demography; Disease Progression; Female; Gastrointestinal Stromal Tumors; Genetic Association Studies; Genetic Predisposition to Disease; Haplotypes; Humans; Imatinib Mesylate; Indoles; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Neovascularization, Pathologic; Polymorphism, Single Nucleotide; Pyrroles; Sunitinib; Time Factors; Treatment Failure; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-3; Young Adult	2017
[Changes of diagnosis and treatment for gastrointestinal stromal tumors during a 18-year period in four medical centers of China]. Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2016, Nov-25, Volume: 19, Issue:11 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; China; Combined Modality Therapy; Exons; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Liver Neoplasms; Male; Middle Aged; Mutation; Neoplasm Recurrence, Local; Proto-Oncogene Proteins c-kit; Pyrroles; Retrospective Studies; Sunitinib; Survival Rate; Young Adult	2016
Gastrointestinal stromal tumours (GISTs): A descriptive study on 29 cases. Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology, 2016, Volume: 17, Issue:4 Topics: Abdominal Pain; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Intestinal Neoplasms; Intestine, Small; Male; Middle Aged; Proto-Oncogene Proteins c-kit; Pyrroles; Retrospective Studies; Stomach Neoplasms; Sunitinib; Survival Rate; Tumor Burden; Weight Loss	2016
Surgical management of patients with progressing metastatic gastrointestinal stromal tumors receiving sunitinib treatment: A prospective cohort study. International journal of surgery (London, England), 2017, Volume: 39 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Combined Modality Therapy; Cytoreduction Surgical Procedures; Disease Progression; Disease-Free Survival; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Indoles; Male; Middle Aged; Mutation; Neoplasm Metastasis; Postoperative Complications; Prospective Studies; Pyrroles; Sunitinib; Treatment Outcome; Young Adult	2017
Successful treatment of a metastatic, gastrointestinal stromal tumour in a dog with toceranib phosphate (Palladia). The Journal of small animal practice, 2017, Volume: 58, Issue:7 Topics: Animals; Antineoplastic Agents; Dog Diseases; Dogs; Female; Gastrointestinal Stromal Tumors; Indoles; Mutation; Neoplasm Recurrence, Local; Proto-Oncogene Proteins c-kit; Pyrroles	2017
Insulin-like growth factor 1 receptor is a potential therapeutic target for gastrointestinal stromal tumors. Proceedings of the National Academy of Sciences of the United States of America, 2008, Jun-17, Volume: 105, Issue:24 Topics: Antineoplastic Agents; Apoptosis; Benzamides; Cell Line, Tumor; Cell Proliferation; DNA Mutational Analysis; Gastrointestinal Stromal Tumors; Gene Amplification; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Imatinib Mesylate; Mitogen-Activated Protein Kinase Kinases; Mutation; Piperazines; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, IGF Type 1; Receptor, Platelet-Derived Growth Factor alpha; RNA, Small Interfering; Signal Transduction	2008
Heterogeneity of kinase inhibitor resistance mechanisms in GIST. The Journal of pathology, 2008, Volume: 216, Issue:1 Topics: Aged; Antineoplastic Agents; Benzamides; Drug Resistance, Neoplasm; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Sunitinib	2008
The clinical implications of sunitinib-induced hypothyroidism: a prospective evaluation. British journal of cancer, 2008, Aug-05, Volume: 99, Issue:3 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Female; Gastrointestinal Stromal Tumors; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Male; Middle Aged; Prospective Studies; Pyrroles; Sunitinib; Thyroid Function Tests	2008
The case / progressive hypertension and proteinuria on anti-angiogenic therapy. Kidney international, 2008, Volume: 74, Issue:5 Topics: Aged; Angiogenesis Inhibitors; Antineoplastic Agents; Female; Gastrointestinal Stromal Tumors; Humans; Hypertension; Indoles; Kidney; Models, Biological; Proteinuria; Pyrroles; Sunitinib; Syndrome; Vascular Endothelial Growth Factor A	2008
Perforation of the colon by invading recurrent gastrointestinal stromal tumors during sunitinib treatment. World journal of gastroenterology, 2008, Oct-21, Volume: 14, Issue:39 Topics: Aged; Antineoplastic Agents; Benzamides; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Intestinal Perforation; Male; Neoplasm Recurrence, Local; Peritonitis; Piperazines; Pyrimidines; Pyrroles; Sunitinib	2008
Prognosis, imatinib dose, and benefit of sunitinib in GIST: knowing the genotype. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Nov-20, Volume: 26, Issue:33 Topics: Benzamides; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Piperazines; Prognosis; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sunitinib	2008
Imatinib-induced interstitial lung disease and sunitinib-associated intra-tumour haemorrhage. Hong Kong medical journal = Xianggang yi xue za zhi, 2008, Volume: 14, Issue:6 Topics: Antineoplastic Agents; Benzamides; Gastrointestinal Stromal Tumors; Hemorrhage; Humans; Imatinib Mesylate; Indoles; Lung Diseases, Interstitial; Male; Middle Aged; Piperazines; Pyrimidines; Pyrroles; Sunitinib	2008
Pharmacokinetics of sunitinib in an obese patient with a GIST. Annals of oncology : official journal of the European Society for Medical Oncology, 2009, Volume: 20, Issue:3 Topics: Adult; Antineoplastic Agents; Gastrointestinal Stromal Tumors; Humans; Indoles; Male; Obesity; Pyrroles; Sunitinib	2009
KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients. Proceedings of the National Academy of Sciences of the United States of America, 2009, Feb-03, Volume: 106, Issue:5 Topics: Antineoplastic Agents; Benzamides; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Phosphorylation; Piperazines; Pyrimidines; Pyrroles; Receptor Protein-Tyrosine Kinases; Spectrometry, Fluorescence; Sunitinib	2009
Hits and misses in targeting pediatric cancers. Pediatric blood & cancer, 2009, Volume: 52, Issue:7 Topics: Adolescent; Antineoplastic Agents; Benzamides; Child; Child, Preschool; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Infant; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Sunitinib	2009
Activity of nilotinib (AMN-107) alone in advanced gastrointestinal stromal tumors progressing on imatinib and sunitinib. Case report. Chemotherapy, 2009, Volume: 55, Issue:2 Topics: Antineoplastic Agents; Benzamides; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Piperazines; Positron-Emission Tomography; Pyrimidines; Pyrroles; Sunitinib; Tomography, X-Ray Computed	2009
Perioperative tyrosine kinase inhibitors for GIST: standard ... or an idea that needs further investigation? Oncology (Williston Park, N.Y.), 2009, Volume: 23, Issue:1 Topics: Antineoplastic Agents; Benzamides; Clinical Trials as Topic; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Neoadjuvant Therapy; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Sunitinib	2009
Controversies in the surgical management of GIST in the era of imatinib. Oncology (Williston Park, N.Y.), 2009, Volume: 23, Issue:1 Topics: Antineoplastic Agents; Benzamides; Chemotherapy, Adjuvant; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Neoadjuvant Therapy; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Sunitinib	2009
Sunitinib treatment in pediatric patients with advanced GIST following failure of imatinib. Pediatric blood & cancer, 2009, Volume: 52, Issue:7 Topics: Adolescent; Antineoplastic Agents; Benzamides; Child; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Piperazines; Polymerase Chain Reaction; Prognosis; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sunitinib; Survival Rate; Treatment Failure; Treatment Outcome	2009
Sunitinib-induced myxedema coma. The American journal of emergency medicine, 2009, Volume: 27, Issue:3 Topics: Aged; Angiogenesis Inhibitors; Coma; Female; Gastrointestinal Stromal Tumors; Humans; Indoles; Pyrroles; Sunitinib	2009
Sunitinib-resistant gastrointestinal stromal tumors harbor cis-mutations in the activation loop of the KIT gene. International journal of clinical oncology, 2009, Volume: 14, Issue:2 Topics: Adenosine Triphosphate; Antineoplastic Agents; Drug Resistance, Neoplasm; Female; Gastrointestinal Stromal Tumors; Humans; Indoles; Male; Middle Aged; Mutation; Proto-Oncogene Proteins c-kit; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sunitinib	2009
Expanding the boundaries of clinical practice: building on experience with targeted therapies. Annals of oncology : official journal of the European Society for Medical Oncology, 2009, Volume: 20 Suppl 1 Topics: Antineoplastic Agents, Alkylating; Carcinoma, Renal Cell; Gastrointestinal Stromal Tumors; Humans; Indoles; Interferon-alpha; Kidney Neoplasms; Pyrroles; Sunitinib; Survival Analysis	2009
New paradigms in gastrointestinal stromal tumour management. Annals of oncology : official journal of the European Society for Medical Oncology, 2009, Volume: 20 Suppl 1 Topics: Benzamides; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Piperazines; Pyrimidines; Pyrroles; Sunitinib	2009
Tyrosine kinase inhibition in renal cell carcinoma and gastrointestinal stromal tumours: case reports. Annals of oncology : official journal of the European Society for Medical Oncology, 2009, Volume: 20 Suppl 1 Topics: Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Combined Modality Therapy; Female; Gastrointestinal Stromal Tumors; Humans; Indoles; Intestinal Neoplasms; Intestine, Small; Kidney Neoplasms; Male; Middle Aged; Protein-Tyrosine Kinases; Pyrroles; Sunitinib	2009
Nilotinib in the treatment of advanced gastrointestinal stromal tumours resistant to both imatinib and sunitinib. European journal of cancer (Oxford, England : 1990), 2009, Volume: 45, Issue:13 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzamides; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Patient Selection; Piperazines; Pyrimidines; Pyrroles; Retrospective Studies; Sunitinib; Treatment Outcome; Young Adult	2009
Cutaneous adverse effects in patients treated with the multitargeted kinase inhibitors sorafenib and sunitinib. The British journal of dermatology, 2009, Volume: 161, Issue:5 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Alopecia; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Hepatocellular; Carcinoma, Renal Cell; Drug Eruptions; Female; Foot Dermatoses; Gastrointestinal Stromal Tumors; Hand Dermatoses; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrroles; Retrospective Studies; Skin Diseases; Sorafenib; Stomatitis; Sunitinib; Young Adult	2009
Imatinib mesylate-induced acute liver failure in a patient with gastrointestinal stromal tumors. Medical oncology (Northwood, London, England), 2010, Volume: 27, Issue:3 Topics: Acute Disease; Anti-Inflammatory Agents; Antineoplastic Agents; Benzamides; Chemical and Drug Induced Liver Injury; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Intestinal Neoplasms; Liver; Liver Failure; Middle Aged; Peritoneal Neoplasms; Piperazines; Prednisolone; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Sunitinib	2010
Perfusion patterns of metastatic gastrointestinal stromal tumor lesions under specific molecular therapy. European journal of radiology, 2011, Volume: 77, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Angiography; Antineoplastic Agents; Benzamides; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Molecular Targeted Therapy; Perfusion Imaging; Pilot Projects; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Sunitinib; Tomography, X-Ray Computed; Treatment Outcome	2011
Biomarkers in GIST: partly ready for prime-time use. Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Sep-15, Volume: 15, Issue:18 Topics: Antineoplastic Agents; Biomarkers, Tumor; Disease Progression; Gastrointestinal Stromal Tumors; Humans; Indoles; Predictive Value of Tests; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrroles; Sunitinib; Time Factors	2009
Circulating levels of soluble KIT serve as a biomarker for clinical outcome in gastrointestinal stromal tumor patients receiving sunitinib following imatinib failure. Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Sep-15, Volume: 15, Issue:18 Topics: Adult; Aged; Aged, 80 and over; Benzamides; Biomarkers, Tumor; Clinical Trials, Phase III as Topic; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Solubility; Sunitinib; Survival Rate; Treatment Outcome; Young Adult	2009
Biochemical and pathological response of prostate cancer in a patient with metastatic renal cell carcinoma on sunitinib treatment. Japanese journal of clinical oncology, 2009, Volume: 39, Issue:12 Topics: Benzamides; Carcinoma, Renal Cell; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Kidney Neoplasms; Male; Middle Aged; Piperazines; Prostate-Specific Antigen; Prostatic Neoplasms; Pyrimidines; Pyrroles; Sunitinib	2009
Successful desensitization protocol for hypersensitivity reaction caused by sunitinib in a patient with a gastrointestinal stromal tumor. Japanese journal of clinical oncology, 2010, Volume: 40, Issue:2 Topics: Administration, Oral; Anti-Allergic Agents; Anti-Inflammatory Agents; Antineoplastic Agents; Desensitization, Immunologic; Drug Hypersensitivity; Gastrointestinal Stromal Tumors; Humans; Indoles; Male; Middle Aged; Prednisone; Promethazine; Pyrroles; Sunitinib; Treatment Outcome	2010
Mechanisms of sunitinib resistance in gastrointestinal stromal tumors harboring KITAY502-3ins mutation: an in vitro mutagenesis screen for drug resistance. Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Nov-15, Volume: 15, Issue:22 Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line; Cell Proliferation; Drug Resistance, Neoplasm; Exons; Gastrointestinal Stromal Tumors; Genotype; Humans; Indoles; Mice; Mutagenesis; Mutation; Proto-Oncogene Proteins c-kit; Pyrroles; Sunitinib	2009
Cytoreductive surgery in patients with metastatic gastrointestinal stromal tumor treated with sunitinib malate. Annals of surgical oncology, 2010, Volume: 17, Issue:2 Topics: Adult; Aged; Antineoplastic Agents; Feasibility Studies; Female; Gastrointestinal Stromal Tumors; Humans; Indoles; Male; Middle Aged; Protein-Tyrosine Kinases; Pyrroles; Retrospective Studies; Sunitinib; Survival Rate; Treatment Outcome; Young Adult	2010
Anti-inflammatory M2 type macrophages characterize metastasized and tyrosine kinase inhibitor-treated gastrointestinal stromal tumors. International journal of cancer, 2010, Aug-15, Volume: 127, Issue:4 Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Benzamides; Female; Forkhead Transcription Factors; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Immunoenzyme Techniques; Indoles; Interleukin-10; Intestinal Neoplasms; Macrophages; Male; Piperazines; Prognosis; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Receptors, Cell Surface; Sunitinib; T-Lymphocytes, Regulatory	2010
The potential role of sunitinib in gastrointestinal cancers other than GIST. Critical reviews in oncology/hematology, 2010, Volume: 76, Issue:1 Topics: Angiogenesis Inhibitors; Animals; Clinical Trials as Topic; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Indoles; Pyrroles; Sunitinib	2010
NCCN Task Force report: update on the management of patients with gastrointestinal stromal tumors. Journal of the National Comprehensive Cancer Network : JNCCN, 2010, Volume: 8 Suppl 2 Topics: Antineoplastic Agents; Benzamides; Biomarkers, Tumor; Diagnostic Imaging; DNA Mutational Analysis; Gastrointestinal Stromal Tumors; Gene Expression Profiling; Humans; Imatinib Mesylate; Indoles; Piperazines; Prognosis; Pyrimidines; Pyrroles; Sunitinib	2010
Downsizing treatment with tyrosine kinase inhibitors in patients with advanced gastrointestinal stromal tumors improved resectability. World journal of surgery, 2010, Volume: 34, Issue:9 Topics: Aged; Benzamides; Chemotherapy, Adjuvant; Disease Progression; DNA Mutational Analysis; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Mutation, Missense; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Sequence Deletion; Sunitinib; Survival Analysis; Tomography, X-Ray Computed	2010
Acne rosacea associated imatinib mesylate in a gastrointestinal stromal tumor patient. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2011, Volume: 17, Issue:3 Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Benzamides; Biopsy; Gastrointestinal Stromal Tumors; Histamine Antagonists; Humans; Hyperpigmentation; Imatinib Mesylate; Indoles; Intestinal Neoplasms; Keratoderma, Palmoplantar; Liver Neoplasms; Male; Middle Aged; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Rosacea; Skin; Skin Pigmentation; Sunitinib; Treatment Outcome	2011
Current management of GISTs. Clinical advances in hematology & oncology : H&O, 2010, Volume: 8, Issue:5 Topics: Antineoplastic Agents; Benzamides; Chemotherapy, Adjuvant; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Sunitinib	2010
[Efficacy of tyrosine kinase inhibitor therapy combined with surgical resection in patients with metastatic gastrointestinal stromal tumor]. Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2010, Volume: 13, Issue:7 Topics: Adult; Aged; Benzamides; Disease-Free Survival; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Intraoperative Period; Male; Middle Aged; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Retrospective Studies; Sunitinib; Survival Rate; Treatment Outcome	2010
Receptor tyrosine kinase inhibition, hypertension, and proteinuria: is endothelin the smoking gun? Hypertension (Dallas, Tex. : 1979), 2010, Volume: 56, Issue:4 Topics: Blood Pressure; Carcinoma, Renal Cell; Endothelin-1; Gastrointestinal Stromal Tumors; Heart Rate; Humans; Hypertension; Indoles; Kidney Neoplasms; Models, Biological; Proteinuria; Pyrroles; Receptor Protein-Tyrosine Kinases; Renin; Sunitinib; Vascular Endothelial Growth Factor A	2010
A novel primary KIT exon 9 single nucleotide substitution c.1427G>T (p.Ser476Ile) in a gastrointestinal stromal tumor. Virchows Archiv : an international journal of pathology, 2010, Volume: 457, Issue:5 Topics: Adult; Antineoplastic Agents; Base Sequence; Benzamides; Combined Modality Therapy; Digestive System Surgical Procedures; Disease Progression; Exons; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Liver Neoplasms; Male; Molecular Sequence Data; Peritoneal Neoplasms; Piperazines; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sunitinib	2010
Nilotinib in patients with GIST who failed imatinib and sunitinib: importance of prior surgery on drug bioavailability. Cancer chemotherapy and pharmacology, 2011, Volume: 68, Issue:2 Topics: Adult; Aged; Antineoplastic Agents; Benzamides; Biological Availability; Compassionate Use Trials; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Gastrectomy; Gastrointestinal Stromal Tumors; Half-Life; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Neoplasm Staging; Piperazines; Protease Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Sunitinib; Survival Analysis	2011
Vesicocutaneous fistula formation during treatment with sunitinib malate: Case report. BMC gastroenterology, 2010, Nov-01, Volume: 10 Topics: Antineoplastic Agents; Cutaneous Fistula; Female; Follow-Up Studies; Gastrointestinal Stromal Tumors; Humans; Indoles; Infusions, Intra-Arterial; Middle Aged; Pyrroles; Sunitinib; Tomography, X-Ray Computed; Urinary Fistula	2010
[The role of pathologists in the target therapy of gastrointestinal tumors]. Zhonghua bing li xue za zhi = Chinese journal of pathology, 2010, Volume: 39, Issue:7 Topics: Anoctamin-1; Antineoplastic Agents; Benzamides; Biomarkers, Tumor; Chloride Channels; Drug Delivery Systems; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Membrane Proteins; Neoplasm Proteins; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sunitinib; Vascular Endothelial Growth Factor A	2010
Sunitinib as a second-line therapy for advanced GISTs after failure of imatinib: relationship between efficacy and tumor genotype in Korean patients. Investigational new drugs, 2012, Volume: 30, Issue:2 Topics: Adult; Aged; Antineoplastic Agents; Asian People; Benzamides; Chi-Square Distribution; Disease Progression; Disease-Free Survival; DNA Mutational Analysis; Exons; Female; Gastrointestinal Stromal Tumors; Genetic Predisposition to Disease; Humans; Imatinib Mesylate; Indoles; Kaplan-Meier Estimate; Male; Middle Aged; Molecular Targeted Therapy; Multivariate Analysis; Mutation; Phenotype; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Republic of Korea; Retrospective Studies; Risk Assessment; Risk Factors; Sunitinib; Time Factors; Treatment Failure	2012
Cyclooxygenase-2 expression in gastrointestinal stromal tumours. Asian Pacific journal of cancer prevention : APJCP, 2010, Volume: 11, Issue:4 Topics: Adult; Aged; Antineoplastic Agents; Benzamides; Chi-Square Distribution; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Progression; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Immunohistochemistry; Indoles; Male; Middle Aged; Mitosis; Neoplasm Metastasis; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Retrospective Studies; Sunitinib; Survival Rate; Tumor Burden	2010
Monitoring the effect of targeted therapies in a gastrointestinal stromal tumor xenograft using a clinical PET/CT. Molecular imaging and biology, 2011, Volume: 13, Issue:6 Topics: Animals; Cell Proliferation; Drug Monitoring; Female; Gastrointestinal Stromal Tumors; Humans; Indoles; Mice; Mice, Nude; Molecular Targeted Therapy; Multimodal Imaging; Positron-Emission Tomography; Pyrroles; Sunitinib; Tomography, X-Ray Computed; Tumor Burden; Xenograft Model Antitumor Assays	2011
Comparison of RECIST and Choi criteria for computed tomographic response evaluation in patients with advanced gastrointestinal stromal tumor treated with sunitinib. Annals of oncology : official journal of the European Society for Medical Oncology, 2011, Volume: 22, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Disease-Free Survival; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Indoles; Male; Middle Aged; Neoplasm Staging; Predictive Value of Tests; Pyrroles; Randomized Controlled Trials as Topic; Sunitinib; Tomography, Emission-Computed	2011
[Management of hypothyroidism secondary to tyrosine kinase inhibitors: description of treatment in three distinct clinical settings]. Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2011, Volume: 58, Issue:2 Topics: Adult; Benzamides; Benzenesulfonates; Carcinoma, Renal Cell; Choristoma; Female; Gastrointestinal Stromal Tumors; Humans; Hypothyroidism; Imatinib Mesylate; Indoles; Kidney Neoplasms; Middle Aged; Niacinamide; Phenylurea Compounds; Piperazines; Pleural Diseases; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Pyrroles; Sorafenib; Sunitinib; Thymus Gland; Thyroxine	2011
Mutational spectrum and therapy response of metastasized GIST in Central Switzerland - a population-based study. European journal of cancer (Oxford, England : 1990), 2011, Volume: 47, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Base Sequence; Benzamides; Disease Progression; DNA Mutational Analysis; DNA Primers; Exons; Female; Gastrointestinal Stromal Tumors; Genetics, Population; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Molecular Sequence Data; Mutation; Neoplasm Metastasis; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Retrospective Studies; Sunitinib; Switzerland	2011
Surgical intervention for imatinib and sunitinib-resistant gastrointestinal stromal tumors. International journal of clinical oncology, 2011, Volume: 16, Issue:6 Topics: Aged; Antineoplastic Agents; Benzamides; Drug Resistance, Neoplasm; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Hepatectomy; Humans; Imatinib Mesylate; Indoles; Liver Neoplasms; Male; Mutation; Neoplasm Metastasis; Neoplasm Recurrence, Local; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Radiography; Sunitinib	2011
Long-term exposure of gastrointestinal stromal tumor cells to sunitinib induces epigenetic silencing of the PTEN gene. International journal of cancer, 2012, Feb-15, Volume: 130, Issue:4 Topics: Antineoplastic Agents; Benzamides; Cell Line, Tumor; Drug Resistance, Neoplasm; Epigenesis, Genetic; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Piperazines; PTEN Phosphohydrolase; Pyrimidines; Pyrroles; Sunitinib	2012
Treatment of gastrointestinal stromal tumor after imatinib and sunitinib. Current opinion in oncology, 2011, Volume: 23, Issue:4 Topics: Antineoplastic Agents; Benzamides; Clinical Trials as Topic; Disease Progression; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sunitinib; Treatment Failure	2011
Sunitinib for Taiwanese patients with gastrointestinal stromal tumor after imatinib treatment failure or intolerance. World journal of gastroenterology, 2011, Apr-28, Volume: 17, Issue:16 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Gastrointestinal Stromal Tumors; Humans; Indoles; Male; Middle Aged; Mutation; Proto-Oncogene Proteins c-kit; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Retrospective Studies; Sunitinib; Taiwan; Treatment Failure; Treatment Outcome; Young Adult	2011
[Evidence-based treatment of gastrointestinal stromal tumor (GIST) with tyrosine kinase inhibitors-imatinib and sunitinib]. Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:5 Topics: Antineoplastic Agents; Benzamides; Combined Modality Therapy; Disease Progression; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Recurrence; Sunitinib	2011
[A case of imatinib-resistant GIST treated by sunitinib]. Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:5 Topics: Antineoplastic Agents; Benzamides; Drug Resistance, Neoplasm; Fatal Outcome; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Liver Neoplasms; Male; Middle Aged; Piperazines; Pyrimidines; Pyrroles; Quality of Life; Sunitinib; Tomography, X-Ray Computed	2011
[KIT and KIT: from biology to clinical use]. Bulletin du cancer, 2012, Feb-01, Volume: 99, Issue:2 Topics: Antineoplastic Agents; Benzamides; Benzenesulfonates; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Niacinamide; Phenylurea Compounds; Piperazines; Piperidines; Prognosis; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins c-kit; Pyridines; Pyrimidines; Pyrroles; Sorafenib; Sunitinib; Thiazoles	2012
[Sunitinib as a second-line therapy for imatinib-resistant gastrointestinal stromal tumors]. Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:6 Topics: Antineoplastic Agents; Benzamides; Clinical Trials as Topic; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Piperazines; Pyrimidines; Pyrroles; Salvage Therapy; Sunitinib	2011
The Novel HSP90 inhibitor, IPI-493, is highly effective in human gastrostrointestinal stromal tumor xenografts carrying heterogeneous KIT mutations. Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Sep-01, Volume: 17, Issue:17 Topics: Animals; Antineoplastic Agents; Apoptosis; Benzamides; Benzoquinones; Cell Line, Tumor; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; HSP90 Heat-Shock Proteins; Humans; Imatinib Mesylate; Indoles; Lactams, Macrocyclic; Mice; Mice, Nude; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Stem Cell Factor; Sunitinib; Xenograft Model Antitumor Assays	2011
Sunitinib-induced hypothyroidism is due to induction of type 3 deiodinase activity and thyroidal capillary regression. The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:10 Topics: Aged; Animals; Antineoplastic Agents; Body Weight; Capillaries; Carcinoma, Renal Cell; Female; Gastrointestinal Stromal Tumors; Humans; Hypothyroidism; Indoles; Iodide Peroxidase; Kidney Neoplasms; Male; Middle Aged; Prospective Studies; Protein-Tyrosine Kinases; Pyrroles; Rats; Rats, Inbred WKY; Regional Blood Flow; Regression Analysis; Retrospective Studies; Stomach Neoplasms; Sunitinib; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine	2011
VEGF expression is related to good response and long progression-free survival in gastrointestinal stromal tumor patients treated with Sunitinib. Diagnostic molecular pathology : the American journal of surgical pathology, part B, 2011, Volume: 20, Issue:3 Topics: Adult; Aged; Antineoplastic Agents; Biomarkers, Tumor; Disease-Free Survival; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Gene Expression Regulation, Neoplastic; Genotype; Humans; Indoles; Male; Middle Aged; Prognosis; Pyrroles; Receptors, Platelet-Derived Growth Factor; Sunitinib; Treatment Outcome; Vascular Endothelial Growth Factor A	2011
The heat shock protein 90 inhibitor IPI-504 induces KIT degradation, tumor shrinkage, and cell proliferation arrest in xenograft models of gastrointestinal stromal tumors. Molecular cancer therapeutics, 2011, Volume: 10, Issue:10 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Benzoquinones; Cell Growth Processes; Cell Line, Tumor; Female; Gastrointestinal Stromal Tumors; HSP90 Heat-Shock Proteins; Humans; Imatinib Mesylate; Indoles; Lactams, Macrocyclic; Mice; Mice, Nude; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sunitinib; Xenograft Model Antitumor Assays	2011
Sunitinib and Thrombosis. Journal of gastrointestinal cancer, 2012, Volume: 43 Suppl 1 Topics: Antineoplastic Agents; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Indoles; Male; Middle Aged; Prognosis; Pyrroles; Sunitinib; Thrombosis	2012
Sunitinib-induced hyperammonemic encephalopathy in gastrointestinal stromal tumors. The Annals of pharmacotherapy, 2011, Volume: 45, Issue:10 Topics: Aged; Antineoplastic Agents; Brain Diseases, Metabolic; Confusion; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Hyperammonemia; Indoles; Male; Middle Aged; Protein Kinase Inhibitors; Pyrroles; Receptor Protein-Tyrosine Kinases; Sunitinib; Treatment Outcome	2011
Sunitinib-induced nephrotic syndrome and irreversible renal dysfunction. Clinical and experimental nephrology, 2012, Volume: 16, Issue:2 Topics: Aged; Antineoplastic Agents; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Indoles; Kidney; Male; Nephrotic Syndrome; Proteinuria; Pyrroles; Sunitinib	2012
Case report of pneumatosis intestinalis secondary to sunitinib treatment for refractory gastrointestinal stromal tumor. Anticancer research, 2011, Volume: 31, Issue:10 Topics: Aged; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Indoles; Male; Pneumatosis Cystoides Intestinalis; Pyrroles; Radiography, Abdominal; Sunitinib; Tomography, X-Ray Computed	2011
Survivin expression and its potential clinical significance in gastrointestinal stromal sarcoma. International immunopharmacology, 2011, Volume: 11, Issue:12 Topics: Adult; Aged; Antineoplastic Agents; Benzamides; Biomarkers, Tumor; Combined Modality Therapy; Disease Progression; Disease-Free Survival; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Inhibitor of Apoptosis Proteins; Male; Middle Aged; Mitosis; Piperazines; Prognosis; Pyrimidines; Pyrroles; Retrospective Studies; Sunitinib; Survivin; Treatment Outcome	2011
Patterns of care, prognosis, and survival in patients with metastatic gastrointestinal stromal tumors (GIST) refractory to first-line imatinib and second-line sunitinib. Annals of surgical oncology, 2012, Volume: 19, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Benzenesulfonates; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Liver Neoplasms; Male; Middle Aged; Multivariate Analysis; Mutation; Niacinamide; Phenylurea Compounds; Piperazines; Prognosis; Proto-Oncogene Proteins c-kit; Pyridines; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Retrospective Studies; Risk Factors; Serum Albumin; Sorafenib; Sunitinib; Survival Rate; Young Adult	2012
Gastrointestinal stromal tumors of the stomach. Surgical oncology clinics of North America, 2012, Volume: 21, Issue:1 Topics: Antineoplastic Agents; Benzamides; Chemotherapy, Adjuvant; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Gastroscopy; Humans; Imatinib Mesylate; Indoles; Laparoscopy; Mutation; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Radiotherapy, Adjuvant; Stomach Neoplasms; Sunitinib	2012
[Twenty-one-year survival case of rectal GIST treated with combined therapies]. Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:12 Topics: Antineoplastic Agents; Benzamides; Combined Modality Therapy; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Neoplasm Metastasis; Piperazines; Pyrimidines; Pyrroles; Rectal Neoplasms; Recurrence; Sunitinib; Time Factors	2011
[A case of gastrointestinal stromal tumor (GIST) successfully treated with resection after a long-term control medication by molecular targeted drugs]. Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:12 Topics: Antineoplastic Agents; Benzamides; Combined Modality Therapy; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Intestinal Neoplasms; Male; Middle Aged; Molecular Targeted Therapy; Piperazines; Pyrimidines; Pyrroles; Sunitinib; Tomography, X-Ray Computed	2011
Intracranial metastasis from pediatric GI stromal tumor. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Apr-01, Volume: 30, Issue:10 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Benzenesulfonates; Brain Neoplasms; Drug Administration Schedule; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Liver Neoplasms; Male; Niacinamide; Phenylurea Compounds; Piperazines; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Pyrroles; Sorafenib; Stomach Neoplasms; Sunitinib; Treatment Outcome	2012
Neoadjuvant use of sunitinib in locally advanced GIST with intolerance to imatinib. Chemotherapy, 2012, Volume: 58, Issue:1 Topics: Antineoplastic Agents; Benzamides; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Neoadjuvant Therapy; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sunitinib; Tomography, X-Ray Computed	2012
The outcome and predictive factors of sunitinib therapy in advanced gastrointestinal stromal tumors (GIST) after imatinib failure - one institution study. BMC cancer, 2012, Mar-22, Volume: 12 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzamides; Disease-Free Survival; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Multivariate Analysis; Piperazines; Polymorphism, Single Nucleotide; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Sunitinib; Treatment Outcome; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Young Adult	2012
Efficacy and safety of sunitinib in Chinese patients with imatinib-resistant or -intolerant gastrointestinal stromal tumors. Future oncology (London, England), 2012, Volume: 8, Issue:5 Topics: Antineoplastic Agents; Asian People; Benzamides; China; Drug Resistance, Neoplasm; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Mutation; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sunitinib; Survival Analysis; Treatment Outcome	2012
Surgery after treatment with imatinib and/or sunitinib in patients with metastasized gastrointestinal stromal tumors: is it worthwhile? World journal of surgical oncology, 2012, Jun-15, Volume: 10 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Combined Modality Therapy; Disease Progression; Feasibility Studies; Female; Follow-Up Studies; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Piperazines; Prognosis; Pyrimidines; Pyrroles; Retrospective Studies; Sunitinib; Survival Rate; Young Adult	2012
Role of operative therapy in treatment of metastatic gastrointestinal stromal tumors. The Journal of surgical research, 2012, Volume: 177, Issue:2 Topics: Aged; Antineoplastic Agents; Benzamides; Disease-Free Survival; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Minnesota; Neoplasm Metastasis; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Retrospective Studies; Sunitinib	2012
[Secondary mutation of c-kit/PDGFRα genotypes after imatinib mesylate therapy and its relationship with efficacy of sunitinib]. Zhonghua bing li xue za zhi = Chinese journal of pathology, 2012, Volume: 41, Issue:6 Topics: Antineoplastic Agents; Benzamides; Disease-Free Survival; Drug Resistance, Neoplasm; Exons; Female; Gastrointestinal Stromal Tumors; Genotype; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Mutation; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sunitinib	2012
Rapid relapse after resection of a sunitinib-resistant gastrointestinal stromal tumor harboring a secondary mutation in exon 13 of the c-KIT gene. Anticancer research, 2012, Volume: 32, Issue:9 Topics: Antineoplastic Agents; Drug Resistance, Neoplasm; Exons; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Indoles; Liver Neoplasms; Male; Middle Aged; Point Mutation; Proto-Oncogene Proteins c-kit; Pyrroles; Recurrence; Sunitinib	2012
[Responses to treatment and switching tyrosine kinase inhibitors in gastrointestinal stromal tumor(GIST)]. Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:9 Topics: Benzamides; Drug Resistance, Neoplasm; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Sunitinib; Treatment Outcome	2012
Sunitinib- and sorafenib-induced nephrotic syndrome in a patient with gastrointestinal stromal tumor. The Annals of pharmacotherapy, 2012, Volume: 46, Issue:10 Topics: Angiogenesis Inhibitors; Benzenesulfonates; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Indoles; Middle Aged; Nephrotic Syndrome; Niacinamide; Phenylurea Compounds; Pyridines; Pyrroles; Sorafenib; Sunitinib	2012
Sorafenib as third- or fourth-line treatment of advanced gastrointestinal stromal tumour and pretreatment including both imatinib and sunitinib, and nilotinib: A retrospective analysis. European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Chemotherapy, Adjuvant; Disease Progression; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Niacinamide; Phenylurea Compounds; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Retrospective Studies; Salvage Therapy; Sorafenib; Sunitinib; Treatment Outcome; Young Adult	2013
Efficacy of sunitinib in Turkish patients with gastrointestinal stromal tumors; retrospective multicenter experience. Hepato-gastroenterology, 2013, Volume: 60, Issue:124 Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Indoles; Male; Middle Aged; Pyrroles; Retrospective Studies; Sunitinib; Treatment Outcome; Turkey	2013
Evaluation of regorafenib in colorectal cancer and GIST. Lancet (London, England), 2013, Jan-26, Volume: 381, Issue:9863 Topics: Antineoplastic Agents; Benzamides; Colorectal Neoplasms; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Phenylurea Compounds; Piperazines; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Pyrroles; Sunitinib	2013
Establishment and characterization of a novel xenograft model of human gastrointestinal stromal tumor in mice. Anticancer research, 2013, Volume: 33, Issue:1 Topics: Aged; Animals; Benzamides; Disease Models, Animal; Esophageal Neoplasms; Exons; Gastrointestinal Stromal Tumors; Gene Expression Regulation, Neoplastic; Humans; Imatinib Mesylate; Indoles; Male; Mice; Molecular Targeted Therapy; Mutation; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sunitinib; Transplantation, Heterologous	2013
[A case of hepatectomy for gastrointestinal stromal tumor with multiple liver metastasis after size reduction in a Jehovah's Witness patient]. Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:12 Topics: Adult; Antineoplastic Agents; Duodenal Neoplasms; Gastrointestinal Stromal Tumors; Hepatectomy; Humans; Indoles; Jehovah's Witnesses; Liver Neoplasms; Male; Pyrroles; Sunitinib	2012
[A case of drug resistant recurrent gastrointestinal stromal tumor treated surgically by resection, partial hepatectomy and diaphragmectomy]. Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:12 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Combined Modality Therapy; Diaphragm; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Hepatectomy; Humans; Imatinib Mesylate; Indoles; Jejunal Neoplasms; Liver Neoplasms; Male; Peritoneal Neoplasms; Piperazines; Pyrimidines; Pyrroles; Recurrence; Sunitinib	2012
ESMO: regorafenib improved PFS for GIST in post-imatinib/sunitinib setting. Oncology (Williston Park, N.Y.), 2012, Volume: 26, Issue:11 Topics: Antineoplastic Agents; Benzamides; Disease-Free Survival; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Phenylurea Compounds; Piperazines; Pyridines; Pyrimidines; Pyrroles; Sunitinib	2012
ZNF-mediated resistance to imatinib mesylate in gastrointestinal stromal tumor. PloS one, 2013, Volume: 8, Issue:1 Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Benzamides; Cell Adhesion Molecules; Cell Line, Tumor; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Library; Genetic Loci; Humans; Imatinib Mesylate; Indoles; Phosphoproteins; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; RNA, Small Interfering; Sunitinib; Transforming Growth Factor beta3; Zinc Fingers	2013
When a thymic carcinoma "becomes" a GIST. Lung cancer (Amsterdam, Netherlands), 2013, Volume: 80, Issue:1 Topics: Antineoplastic Agents; Benzamides; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Mutation; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sunitinib; Thymoma; Thymus Neoplasms; Treatment Failure; Treatment Outcome	2013
New drug increases survival in stomach cancer. The Lancet. Oncology, 2006, Volume: 7, Issue:4 Topics: Gastrointestinal Stromal Tumors; Humans; Indoles; Prognosis; Pyrroles; Stomach Neoplasms; Sunitinib; Survival Analysis; Treatment Outcome	2006
Sunitinib maleate. Nature reviews. Drug discovery, 2006, Volume: 5, Issue:4 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Drug Design; Gastrointestinal Stromal Tumors; Humans; Indoles; Kidney Neoplasms; Pyrroles; Sunitinib; Vascular Endothelial Growth Factor Receptor-2	2006
Efficacy of the kinase inhibitor SU11248 against gastrointestinal stromal tumor mutants refractory to imatinib mesylate. Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Apr-15, Volume: 12, Issue:8 Topics: Animals; Antineoplastic Agents; Benzamides; Cell Line; Cell Proliferation; Disease Progression; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Genotype; Humans; Imatinib Mesylate; Indoles; Mutation; Phosphorylation; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sunitinib; Tumor Cells, Cultured	2006
Surgical management of advanced gastrointestinal stromal tumors after treatment with targeted systemic therapy using kinase inhibitors. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, May-20, Volume: 24, Issue:15 Topics: Adult; Aged; Antineoplastic Agents; Benzamides; Combined Modality Therapy; Disease Progression; Doxorubicin; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Neoplasm Staging; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Retrospective Studies; Sunitinib; Survival Analysis; Treatment Outcome	2006
Effect of SU11248 on gastrointestinal stromal tumor-T1 cells: enhancement of growth inhibition via inhibition of 3-kinase/Akt/mammalian target of rapamycin signaling. Cancer science, 2006, Volume: 97, Issue:9 Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Line, Tumor; Cell Proliferation; Chromones; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Gastrointestinal Stromal Tumors; Humans; Indoles; Morpholines; Phosphotransferases; Protein Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-kit; Pyrroles; Sirolimus; Sunitinib; TOR Serine-Threonine Kinases	2006
ZD6474 induces growth arrest and apoptosis of GIST-T1 cells, which is enhanced by concomitant use of sunitinib. Cancer science, 2006, Volume: 97, Issue:12 Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Apoptosis; Cell Cycle Proteins; Cell Proliferation; Drug Therapy, Combination; Gastrointestinal Stromal Tumors; Humans; Indoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphoproteins; Phosphorylation; Piperidines; Protein Kinases; Proto-Oncogene Proteins c-akt; Pyrroles; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6 Kinases, 70-kDa; STAT3 Transcription Factor; Sunitinib; TOR Serine-Threonine Kinases; Tumor Cells, Cultured	2006
Sunitinib for imatinib-resistant GIST. Lancet (London, England), 2006, Oct-14, Volume: 368, Issue:9544 Topics: Antineoplastic Agents; Benzamides; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Liver Neoplasms; Multicenter Studies as Topic; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Sunitinib	2006
[Sunitinib for gastrointestinal stromal cell tumors and advanced renal cell carcinoma]. Medizinische Monatsschrift fur Pharmazeuten, 2006, Volume: 29, Issue:10 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Disease Progression; Gastrointestinal Stromal Tumors; Humans; Indoles; Kidney Neoplasms; Protein-Tyrosine Kinases; Pyrroles; Sunitinib	2006
The activity of sunitinib against gastrointestinal stromal tumor seems to be distinct from its antiangiogenic effects. Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Oct-15, Volume: 12, Issue:20 Pt 1 Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Cell Division; Enzyme Inhibitors; Female; Gastrointestinal Stromal Tumors; Humans; Indoles; Middle Aged; Neoplasm, Residual; Phosphotransferases; Pyrroles; Sunitinib; Treatment Outcome	2006
Summaries for patients. Underactive thyroid function after treatment with sunitinib for gastrointestinal cancer. Annals of internal medicine, 2006, Nov-07, Volume: 145, Issue:9 Topics: Adult; Antineoplastic Agents; Drug Administration Schedule; Female; Gastrointestinal Stromal Tumors; Humans; Hypothyroidism; Indoles; Prospective Studies; Protein-Tyrosine Kinases; Pyrroles; Sunitinib; Thyroiditis; Thyrotropin	2006
Current and future management of GIST. Clinical advances in hematology & oncology : H&O, 2006, Volume: 4, Issue:8 Topics: Antineoplastic Agents; Benzamides; Benzenesulfonates; Benzoquinones; Disease Progression; Dose-Response Relationship, Drug; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Lactams, Macrocyclic; Niacinamide; Phenylurea Compounds; Piperazines; Pyridines; Pyrimidines; Pyrroles; Sorafenib; Sunitinib; Treatment Outcome	2006
Sunitinib malate. Cancer chemotherapy and pharmacology, 2007, Volume: 60, Issue:3 Topics: Antineoplastic Agents; Carcinoma, Small Cell; Cell Division; Cell Line, Tumor; Disease Progression; Endothelium, Vascular; Enzyme Inhibitors; Gastrointestinal Stromal Tumors; Humans; Indoles; Leukemia, Myeloid; Lung Neoplasms; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Sunitinib	2007
Food and Drug Administration drug approval summary: Sunitinib malate for the treatment of gastrointestinal stromal tumor and advanced renal cell carcinoma. The oncologist, 2007, Volume: 12, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Clinical Trials as Topic; Drug Approval; Female; Gastrointestinal Stromal Tumors; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Pyrroles; Safety; Sunitinib; United States; United States Food and Drug Administration	2007
Emphysematous cholecystitis in a patient with gastrointestinal stromal tumor treated with sunitinib. Pharmacotherapy, 2007, Volume: 27, Issue:5 Topics: Acute Disease; Angiogenesis Inhibitors; Anti-Bacterial Agents; Antineoplastic Agents; Cholecystostomy; Emphysematous Cholecystitis; Gastrointestinal Stromal Tumors; Humans; Hyperbilirubinemia; Indoles; Leukocytosis; Male; Middle Aged; Neoplasm Metastasis; Probability; Pyrroles; Sunitinib; Tomography, X-Ray Computed	2007
Sunitinib induces hypothyroidism in advanced cancer patients and may inhibit thyroid peroxidase activity. Thyroid : official journal of the American Thyroid Association, 2007, Volume: 17, Issue:4 Topics: Gastrointestinal Stromal Tumors; Humans; Hypothyroidism; Indoles; Iodide Peroxidase; Protein-Tyrosine Kinases; Pyrroles; Retrospective Studies; Sunitinib; Thyroid Function Tests	2007
Effect of sunitinib on metastatic gastrointestinal stromal tumor in patients with neurofibromatosis type 1: a case report. World journal of gastroenterology, 2007, May-14, Volume: 13, Issue:18 Topics: Antineoplastic Agents; Gastrointestinal Stromal Tumors; Humans; Indoles; Liver Neoplasms; Male; Middle Aged; Neurofibromatosis 1; Omentum; Pyrroles; Sunitinib	2007
Improved insight into resistance mechanisms to imatinib in gastrointestinal stromal tumors: a basis for novel approaches and individualization of treatment. The oncologist, 2007, Volume: 12, Issue:6 Topics: Antineoplastic Agents; Benzamides; Disease Progression; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Piperazines; Pyrimidines; Pyrroles; Sunitinib	2007
Tumor lysis syndrome after treatment of a gastrointestinal stromal tumor with the oral tyrosine kinase inhibitor sunitinib. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Aug-10, Volume: 25, Issue:23 Topics: Administration, Oral; Antineoplastic Agents; Fatal Outcome; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Indoles; Male; Middle Aged; Protein Kinase Inhibitors; Pyrroles; Sunitinib; Tumor Lysis Syndrome	2007
[Imatinib . Sunitinib]. Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:8 Topics: Angiogenesis Inhibitors; Benzamides; Carcinoma, Renal Cell; Dermatofibrosarcoma; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Kidney Neoplasms; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Skin Neoplasms; Sunitinib; Survival Rate	2007
Sunitinib: new drug. For some gastrointestinal stromal tumours. Prescrire international, 2007, Volume: 16, Issue:90 Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Gastrointestinal Stromal Tumors; Humans; Hypothyroidism; Indoles; Interferon-alpha; Kidney Neoplasms; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles	2007
Treatment of wild-type gastrointestinal stromal tumor (WT-GIST) with imatinib and sunitinib. Pediatric blood & cancer, 2008, Volume: 50, Issue:2 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sunitinib	2008
[Chemotherapy and target-therapy of gastrointestinal tumors call for development of pathology]. Zhonghua bing li xue za zhi = Chinese journal of pathology, 2007, Volume: 36, Issue:7 Topics: Antineoplastic Agents; Benzamides; Chemotherapy, Adjuvant; ErbB Receptors; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Neoplasm Staging; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sunitinib; Vascular Endothelial Growth Factor A	2007
Potential biomarkers in metastatic gastrointestinal stromal tumors. Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Oct-15, Volume: 13, Issue:20 Topics: Antineoplastic Agents; Biomarkers, Tumor; Blood Platelets; Bone Marrow; Flow Cytometry; Gastrointestinal Stromal Tumors; Humans; Indoles; Interleukin-6; Neoplasm Metastasis; Phenotype; Pyrroles; Sunitinib; Thrombopoietin	2007
Targeting c-KIT, PDGFR in cancer of unknown primary: a screening study for molecular markers of benefit. Journal of cancer research and clinical oncology, 2008, Volume: 134, Issue:6 Topics: Aged; Aged, 80 and over; Benzamides; Exons; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Immunohistochemistry; Indoles; Male; Middle Aged; Mutation; Neoplasms, Unknown Primary; Piperazines; Polymorphism, Genetic; Prognosis; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptors, Platelet-Derived Growth Factor; Sunitinib	2008
Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib. Lancet (London, England), 2007, Dec-15, Volume: 370, Issue:9604 Topics: Animals; Antineoplastic Agents; Blood Pressure; Female; Gastrointestinal Stromal Tumors; Heart Failure; Humans; Indoles; Male; Mice; Middle Aged; Multicenter Studies as Topic; Protein-Tyrosine Kinases; Pyrroles; Rats; Retrospective Studies; Stroke Volume; Sunitinib	2007
Surgical debulking of gastrointestinal stromal tumors: is it a reasonable option after second-line treatment with sunitinib? Journal of cancer research and clinical oncology, 2008, Volume: 134, Issue:5 Topics: Adult; Antineoplastic Agents; Benzamides; Combined Modality Therapy; Digestive System Surgical Procedures; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Liver Neoplasms; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Piperazines; Pyrimidines; Pyrroles; Sunitinib; Tomography, X-Ray Computed	2008
F-18 FDG PET/CT assessment of gastrointestinal stromal tumor response to sunitinib malate therapy. Clinical nuclear medicine, 2008, Volume: 33, Issue:3 Topics: Antineoplastic Agents; Female; Fluorodeoxyglucose F18; Gastrointestinal Stromal Tumors; Humans; Indoles; Liver Neoplasms; Middle Aged; Pyrroles; Radiography; Radionuclide Imaging; Radiopharmaceuticals; Sunitinib	2008
Surgical resection of residual disease in initially inoperable imatinib-resistant/intolerant gastrointestinal stromal tumor treated with sunitinib. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2009, Volume: 35, Issue:1 Topics: Aged; Antineoplastic Agents; Benzamides; Combined Modality Therapy; Disease Progression; Drug Resistance, Neoplasm; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Middle Aged; Neoplasm, Residual; Piperazines; Pyrimidines; Pyrroles; Sunitinib; Treatment Outcome	2009
[Consensus on the medical treatment of gastrointestinal stromal tumors]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 2007, Volume: 29, Issue:11 Topics: Antineoplastic Agents; Benzamides; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Neoplasm Recurrence, Local; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sunitinib	2007
Cardiotoxicity associated with sunitinib. Lancet (London, England), 2008, Apr-12, Volume: 371, Issue:9620 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Cardiovascular Diseases; Gastrointestinal Stromal Tumors; Humans; Indoles; Kidney Neoplasms; Pyrroles; Sunitinib	2008
Off-label uses of sorafenib and sunitinib. Technology Evaluation Center Assessment Program. Executive summary, 2008, Volume: 22, Issue:11 Topics: Adenocarcinoma; Angiogenesis Inhibitors; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Clinical Trials, Phase III as Topic; Digestive System Neoplasms; Drug Approval; Female; Gastrointestinal Stromal Tumors; Head and Neck Neoplasms; Humans; Indoles; Male; Melanoma; Neoplasms, Squamous Cell; Product Labeling; Pyridines; Pyrroles; Randomized Controlled Trials as Topic; Treatment Outcome; United States; United States Food and Drug Administration	2008
Cardiotoxicity associated with the cancer therapeutic agent sunitinib malate. Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Renal Cell; Cohort Studies; Female; Follow-Up Studies; Gastrointestinal Stromal Tumors; Heart Failure; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Probability; Protein-Tyrosine Kinases; Pyrroles; Registries; Retrospective Studies; Risk Assessment; Statistics, Nonparametric; Stroke Volume; Sunitinib; Survival Analysis; Treatment Outcome; Ventricular Dysfunction, Left	2008
Pyoderma gangrenosum: another cutaneous side-effect of sunitinib? The British journal of dermatology, 2008, Volume: 159, Issue:1 Topics: Aged; Antineoplastic Agents; Female; Gastrointestinal Stromal Tumors; Humans; Indoles; Pyoderma Gangrenosum; Pyrroles; Sunitinib; Treatment Outcome	2008
Acute severe hypothyroidism induced by sunitinib. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2008, Volume: 89, Issue:1 Topics: Acute Disease; Aged; Antineoplastic Agents; Female; Gastrointestinal Stromal Tumors; Humans; Hypothyroidism; Indoles; Pyrroles; Sunitinib	2008
A pharmaco-economic analysis of second-line treatment with imatinib or sunitinib in patients with advanced gastrointestinal stromal tumours. British journal of cancer, 2008, Jun-03, Volume: 98, Issue:11 Topics: Adult; Aged; Antineoplastic Agents; Benzamides; Cost-Benefit Analysis; Female; Gastrointestinal Stromal Tumors; Health Care Costs; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Piperazines; Pyrimidines; Pyrroles; Sunitinib	2008