Page last updated: 2024-08-18

pyrroles and Fibrous Histiocytoma of Tendon Sheath

pyrroles has been researched along with Fibrous Histiocytoma of Tendon Sheath in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (5.88)24.3611
2020's16 (94.12)2.80

Authors

AuthorsStudies
French, J; Gelderblom, H; Greenberg, J; Healey, JH; Polhamus, D; Shuster, D; Stacchiotti, S; Tap, WD; van de Sande, M; Wagner, AJ; Wang, X; Yin, O; Zahir, H1
Beckett, B; Hansford, B; Helming, A1
Anthony, SP; Braiteh, F; Chmielowski, B; Cohn, AL; Cote, GM; Gelhorn, HL; Healey, JH; Hsu, HH; Keedy, VL; Lin, PS; Peterfy, C; Puzanov, I; Severson, P; Shapiro, GI; Sherman, E; Singh, AS; Sterba, M; Tap, WD; Tong-Starksen, S; Wagner, AJ; Wainberg, ZA; West, BL; Ye, X; Zhang, C1
Choi, Y; Dharmani, C; Diggs, A; Jiang, J; Keedy, VL; McCabe, C; Salas, M; Wang, E1
Damron, TA1
Lamb, YN1
Donati, DM; Longhi, A; Palmerini, E; Staals, EL1
Benner, B; Carson, WE; Cherian, MA; Good, L; Kassem, M; Quiroga, D; Sardesai, S; Schultz, TE; Wesolowski, R1
Baldi, GG; Gronchi, A; Stacchiotti, S1
Lazaridis, D; Monestime, S1
de Sande, MV; Gelderblom, H1
Tap, W1
Gelderblom, H; Healey, JH; Kang, J; Knebel, W; Shuster, D; Stacchiotti, S; Tap, WD; van de Sande, M; Wagner, AJ; Yin, O; Zahir, H1
Alsayadi, YMMA; Chawla, PA1
Bernthal, NM; Desai, J; Frezza, AM; Gelderblom, H; Healey, JH; Hsu, HH; Palmerini, E; Peterfy, CG; Shuster, DE; Staals, EL; Stacchiotti, S; Tap, WD; van de Sande, MAJ; Wagner, AJ; Wainberg, ZA; Wang, Q1
Baba, HA; Bauer, S; Choi, Y; Druta, M; Gelderblom, H; Healey, JH; Lewis, JH; Lin, CC; Pousa, AL; Shuster, DE; Stacchiotti, S; Tap, WD; van de Sande, M; Wagner, AJ; Wang, Q1
Alcindor, T; Desai, J; Ganjoo, K; Gelderblom, H; Gelhorn, HL; Healey, JH; Martín-Broto, J; Palmerini, E; Shuster, D; Speck, RM; Stacchiotti, S; Tap, WD; Van De Sande, M; Wagner, AJ; Wang, Q; Ye, X1

Reviews

8 review(s) available for pyrroles and Fibrous Histiocytoma of Tendon Sheath

ArticleYear
Turalio risk evaluation and mitigation strategy for treatment of tenosynovial giant cell tumor: framework and experience.
    Future oncology (London, England), 2022, Volume: 18, Issue:13

    Topics: Adult; Aminopyridines; Giant Cell Tumor of Tendon Sheath; Humans; Pyrroles; Risk Evaluation and Mitigation; United States; United States Food and Drug Administration

2022
Pexidartinib: First Approval.
    Drugs, 2019, Volume: 79, Issue:16

    Topics: Aminopyridines; Antineoplastic Agents; Drug Approval; fms-Like Tyrosine Kinase 3; Giant Cell Tumor of Tendon Sheath; Humans; Macrophage Colony-Stimulating Factor; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins c-kit; Pyrroles; United States; United States Food and Drug Administration

2019
Pexidartinib for the treatment of adult patients with symptomatic tenosynovial giant cell tumor: safety and efficacy.
    Expert review of anticancer therapy, 2020, Volume: 20, Issue:6

    Topics: Adult; Aminopyridines; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Giant Cell Tumor of Tendon Sheath; Humans; Macrophage Colony-Stimulating Factor; Neoplasm Recurrence, Local; Pyrroles; Quality of Life

2020
Pexidartinib, a Novel Small Molecule CSF-1R Inhibitor in Use for Tenosynovial Giant Cell Tumor: A Systematic Review of Pre-Clinical and Clinical Development.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Aminopyridines; Antineoplastic Agents; Clinical Trials as Topic; Dose-Response Relationship, Drug; Giant Cell Tumor of Tendon Sheath; Humans; Molecular Structure; Pyrroles; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Structure-Activity Relationship

2020
Pexidartinib for the treatment of adult symptomatic patients with tenosynovial giant cell tumors.
    Expert review of clinical pharmacology, 2020, Volume: 13, Issue:6

    Topics: Adult; Aminopyridines; Antineoplastic Agents; Giant Cell Tumor of Tendon Sheath; Humans; Macrophage Colony-Stimulating Factor; Neoplasm Recurrence, Local; Pyrroles; Quality of Life; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor

2020
Pexidartinib (TURALIO™): The First FDA-Indicated Systemic Treatment for Tenosynovial Giant Cell Tumor.
    Drugs in R&D, 2020, Volume: 20, Issue:3

    Topics: Administration, Oral; Adult; Aminopyridines; Antineoplastic Agents; Clinical Trials as Topic; Contraindications, Drug; Drug Approval; Drug Interactions; Female; Giant Cell Tumor of Tendon Sheath; Humans; Macrophage Colony-Stimulating Factor; Male; Middle Aged; Protein Kinase Inhibitors; Pyrroles; United States; United States Food and Drug Administration

2020
Pexidartinib: first approved systemic therapy for patients with tenosynovial giant cell tumor.
    Future oncology (London, England), 2020, Volume: 16, Issue:29

    Topics: Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Diagnostic Imaging; Disease Management; Giant Cell Tumor of Tendon Sheath; Humans; Molecular Targeted Therapy; Neoplasm Staging; Protein Kinase Inhibitors; Pyrroles; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Structure-Activity Relationship; Treatment Outcome

2020
Prospects of Treating Tenosynovial Giant Cell Tumor through Pexidartinib: A Review.
    Anti-cancer agents in medicinal chemistry, 2021, Volume: 21, Issue:12

    Topics: Aminopyridines; Antineoplastic Agents; Giant Cell Tumor of Tendon Sheath; Humans; Macrophage Colony-Stimulating Factor; Pyrroles; Receptor, Macrophage Colony-Stimulating Factor; United States; United States Food and Drug Administration

2021

Trials

2 trial(s) available for pyrroles and Fibrous Histiocytoma of Tendon Sheath

ArticleYear
Population Pharmacokinetic Analysis of Pexidartinib in Healthy Subjects and Patients With Tenosynovial Giant Cell Tumor or Other Solid Tumors.
    Journal of clinical pharmacology, 2021, Volume: 61, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aminopyridines; Antineoplastic Agents; Area Under Curve; Asian People; Bacterial Proteins; Body Weight; Creatinine; Female; Giant Cell Tumor of Tendon Sheath; Humans; Kidney Function Tests; Liver Function Tests; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Pyrroles; Racial Groups; Sex Factors; Sociodemographic Factors; Tumor Burden; Young Adult

2021
Pexidartinib improves physical functioning and stiffness in patients with tenosynovial giant cell tumor: results from the ENLIVEN randomized clinical trial.
    Acta orthopaedica, 2021, Volume: 92, Issue:4

    Topics: Adult; Aminopyridines; Double-Blind Method; Female; Giant Cell Tumor of Tendon Sheath; Humans; Lower Extremity; Male; Middle Aged; Patient Reported Outcome Measures; Pyrroles

2021

Other Studies

7 other study(ies) available for pyrroles and Fibrous Histiocytoma of Tendon Sheath

ArticleYear
Exposure-response analysis of efficacy and safety for pexidartinib in patients with tenosynovial giant cell tumor.
    CPT: pharmacometrics & systems pharmacology, 2021, Volume: 10, Issue:11

    Topics: Aminopyridines; Giant Cell Tumor of Tendon Sheath; Humans; Pyrroles; Response Evaluation Criteria in Solid Tumors

2021
Tenosynovial giant cell tumor-diffuse type, treated with a novel colony-stimulating factor inhibitor, pexidartinib: initial experience with MRI findings in three patients.
    Skeletal radiology, 2022, Volume: 51, Issue:5

    Topics: Adult; Aminopyridines; Colony-Stimulating Factors; Giant Cell Tumor of Tendon Sheath; Humans; Magnetic Resonance Imaging; Pyrroles; Synovitis, Pigmented Villonodular

2022
Results from Phase I Extension Study Assessing Pexidartinib Treatment in Six Cohorts with Solid Tumors including TGCT, and Abnormal CSF1 Transcripts in TGCT.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 01-15, Volume: 28, Issue:2

    Topics: Adult; Aminopyridines; Giant Cell Tumor of Tendon Sheath; Humans; Protein Kinase Inhibitors; Pyrroles

2022
CORR Insights®: Pexidartinib Provides Modest Pain Relief in Patients With Tenosynovial Giant Cell Tumor: Results From ENLIVEN.
    Clinical orthopaedics and related research, 2023, 01-01, Volume: 481, Issue:1

    Topics: Aminopyridines; Giant Cell Tumor of Tendon Sheath; Humans; Pain; Pyrroles

2023
ENLIVEN study: Pexidartinib for tenosynovial giant cell tumor (TGCT).
    Future oncology (London, England), 2020, Volume: 16, Issue:25

    Topics: Aminopyridines; Giant Cell Tumor of Tendon Sheath; Humans; Protein Kinase Inhibitors; Pyrroles; Synovitis, Pigmented Villonodular

2020
Long-term outcomes of pexidartinib in tenosynovial giant cell tumors.
    Cancer, 2021, 03-15, Volume: 127, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Aminopyridines; Female; Giant Cell Tumor of Tendon Sheath; Humans; Male; Middle Aged; Pyrroles; Young Adult

2021
Pexidartinib Long-Term Hepatic Safety Profile in Patients with Tenosynovial Giant Cell Tumors.
    The oncologist, 2021, Volume: 26, Issue:5

    Topics: Aminopyridines; Chemical and Drug Induced Liver Injury; Giant Cell Tumor of Tendon Sheath; Humans; Liver; Pyrroles

2021