Compounds > pyrroles
Page last updated: 2024-08-18

pyrroles and Drug Withdrawal Symptoms

pyrroles has been researched along with Drug Withdrawal Symptoms in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.69)18.7374
1990's2 (7.69)18.2507
2000's15 (57.69)29.6817
2010's5 (19.23)24.3611
2020's2 (7.69)2.80

Authors

AuthorsStudies
Almela, P; Cánovas, A; Gómez-Murcia, V; Laorden, ML; Martínez-Laorden, E; Milanés, MV; Navarro-Zaragoza, J; Teruel-Fernández, FJ1
Berry, JN; Prendergast, MA; Reynolds, AR; Saunders, MA; Sharrett-Field, LJ; Winchester, S1
Almela, P; Laorden, ML; Martínez-Laorden, E; Milanés, MV; Navarro-Zaragoza, J1
de Oliveira, CV; Funck, VR; Furian, AF; Grigoletto, J; Oliveira, MS; Pereira, LM; Rambo, LM; Ribeiro, LR; Royes, LF1
Negus, SS; Rice, KC1
Breese, GR; Fee, JR; Ferraro, FM; Knapp, DJ; Sparta, DR; Thiele, TE1
Bhutada, PS; Mundhada, YR; Umathe, SN1
Almela, P; García-Carmona, JA; Hidalgo, J; Laorden, ML; Milanés, MV; Mora, L; Navarro-Zaragoza, J1
Arora, S; Rehni, AK; Singh, TG1
Böhm, M; Dirnagl, U; Endres, M; Gertz, K; Laufs, U; Lindauer, U; Nickenig, G1
Cador, M; Koob, GF; Stinus, L; Zorrilla, EP1
Chu, CS; Lai, WT; Lee, KT; Sheu, SH; Tsai, LY; Voon, WC; Yen, HW1
McGowan, MP1
Mamiya, T; Matsumura, T; Ukai, M1
Breese, GR; Knapp, DJ; Navarro, M; Overstreet, DH1
Chu, CS; Lai, WT; Lee, KT; Lee, MY; Sheu, SH; Su, HM; Voon, WC1
Chen, SH; Chu, CS; Kou, HS; Lai, WT; Lee, CJ; Lee, KT; Sheu, SH; Voon, WC1
Bax, JJ; Davignon, J; Dunkelgrun, M; Feringa, HH; Hoeks, SE; Kastelein, JJ; Poldermans, D; Schouten, O; van Domburg, RT; Vidakovic, R; Welten, GM1
Bassi, A; Caltagirone, C; Colivicchi, F; Santini, M1
Divin, MF; Holden Ko, MC; Traynor, JR1
Baeyens, JM; Barrios, M; Robles, LI1
Kamei, J; Ohsawa, M1
Alvaro, JD; Chen, YL; Duman, RS; Iredale, PA; Lee, Y; Terwilliger, R1
Ceng, X; Liu, D; Lu, L; Ma, L1
Azzollini, F; Lodola, E1
Martinetti, L; Monafo, V1

Trials

4 trial(s) available for pyrroles and Drug Withdrawal Symptoms

ArticleYear
There is no evidence for an increase in acute coronary syndromes after short-term abrupt discontinuation of statins in stable cardiac patients.
    Circulation, 2004, Oct-19, Volume: 110, Issue:16

    Topics: Acute Disease; Atorvastatin; Coronary Disease; Disease-Free Survival; Double-Blind Method; Heart Arrest; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Life Tables; Myocardial Infarction; Myocardial Ischemia; Pyrroles; Stroke; Substance Withdrawal Syndrome; Syndrome; Withholding Treatment

2004
Effects of atorvastatin and atorvastatin withdrawal on soluble CD40L and adipocytokines in patients with hypercholesterolaemia.
    Acta cardiologica, 2006, Volume: 61, Issue:3

    Topics: Adiponectin; Aged; Anticholesteremic Agents; Atorvastatin; CD40 Ligand; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pyrroles; Resistin; Substance Withdrawal Syndrome; Triglycerides

2006
Diviminol (Z 424): a pilot study for prolonged clinical use.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1971, Volume: 4, Issue:3

    Topics: Adult; Aged; Amines; Amino Alcohols; Analgesics; Benzyl Compounds; Blood Pressure; Body Temperature; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Nalorphine; Pain; Pulse; Pyrroles; Respiration; Substance Withdrawal Syndrome

1971
A clinical study of diviminol on prolonged administration.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1971, Volume: 4, Issue:3

    Topics: Adult; Aged; Amines; Amino Alcohols; Analgesics; Benzyl Compounds; Blood Pressure; Clinical Trials as Topic; Drug Tolerance; Female; Humans; Male; Middle Aged; Pain; Pulse; Pyrroles; Respiration; Substance Withdrawal Syndrome

1971

Other Studies

22 other study(ies) available for pyrroles and Drug Withdrawal Symptoms

ArticleYear
Naloxone-induced conditioned place aversion score and extinction period are higher in C57BL/6J morphine-dependent mice than in Swiss: Role of HPA axis.
    Pharmacology, biochemistry, and behavior, 2021, Volume: 201

    Topics: Animals; Avoidance Learning; Conditioning, Operant; Extinction, Psychological; Hypothalamo-Hypophyseal System; Male; Memory; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Pituitary-Adrenal System; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Substance Withdrawal Syndrome

2021
Broad-spectrum protein kinase inhibition by the staurosporine analog KT-5720 reverses ethanol withdrawal-associated loss of NeuN/Fox-3.
    Alcohol (Fayetteville, N.Y.), 2017, Volume: 64

    Topics: Animals; Antigens, Nuclear; Carbazoles; DNA-Binding Proteins; Ethanol; Hippocampus; Nerve Tissue Proteins; Nuclear Proteins; Organ Culture Techniques; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Sprague-Dawley; Staurosporine; Substance Withdrawal Syndrome

2017
Conditioned aversive memory associated with morphine withdrawal increases brain-derived neurotrophic factor in dentate gyrus and basolateral amygdala.
    Addiction biology, 2020, Volume: 25, Issue:4

    Topics: Affect; Analgesics, Opioid; Animals; Basolateral Nuclear Complex; Brain-Derived Neurotrophic Factor; Conditioning, Classical; Corticosterone; Corticotropin-Releasing Hormone; Cyclic AMP Response Element-Binding Protein; Dentate Gyrus; Extinction, Psychological; Male; Memory; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morphine; Naloxone; Narcotic Antagonists; Protein Precursors; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Substance Withdrawal Syndrome

2020
Atorvastatin withdrawal elicits oxidative/nitrosative damage in the rat cerebral cortex.
    Pharmacological research, 2013, Volume: 71

    Topics: Animals; Atorvastatin; Cerebral Cortex; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Nitric Oxide; Oxidation-Reduction; Pyrroles; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Superoxide Dismutase; Tyrosine

2013
Mechanisms of withdrawal-associated increases in heroin self-administration: pharmacologic modulation of heroin vs food choice in heroin-dependent rhesus monkeys.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:4

    Topics: Adrenergic Agents; Adrenergic Agonists; Amphetamine; Animals; Behavior, Addictive; Choice Behavior; Clonidine; Dopamine Agents; Dose-Response Relationship, Drug; Food; Heroin; Heroin Dependence; Macaca mulatta; Male; Morphine; Narcotic Antagonists; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Self Administration; Substance Withdrawal Syndrome

2009
The alcohol deprivation effect in C57BL/6J mice is observed using operant self-administration procedures and is modulated by CRF-1 receptor signaling.
    Alcoholism, clinical and experimental research, 2009, Volume: 33, Issue:1

    Topics: Alcoholism; Animals; Conditioning, Operant; Ethanol; Male; Mice; Mice, Inbred C57BL; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Self Administration; Signal Transduction; Substance Withdrawal Syndrome

2009
Differential effects of acute morphine, and chronic morphine-withdrawal on obsessive-compulsive behavior: inhibitory influence of CRF receptor antagonists on chronic morphine-withdrawal.
    Neuropeptides, 2012, Volume: 46, Issue:5

    Topics: Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; Morphine; Motor Activity; Narcotics; Obsessive-Compulsive Disorder; Peptide Fragments; Peptides, Cyclic; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Substance Withdrawal Syndrome

2012
Role of corticotropin-releasing factor (CRF) receptor-1 on the catecholaminergic response to morphine withdrawal in the nucleus accumbens (NAc).
    PloS one, 2012, Volume: 7, Issue:10

    Topics: Animals; Corticosterone; Dopamine; Male; Morphine; Morphine Dependence; Naloxone; Neurons; Norepinephrine; Nucleus Accumbens; Phosphorylation; Proto-Oncogene Proteins c-fos; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Serine; Substance Withdrawal Syndrome; Tyrosine 3-Monooxygenase; Ventral Tegmental Area

2012
Ro 32-0432 attenuates mecamylamine-precipitated nicotine withdrawal syndrome in mice.
    Naunyn-Schmiedeberg's archives of pharmacology, 2013, Volume: 386, Issue:3

    Topics: Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; G-Protein-Coupled Receptor Kinase 5; Indoles; Male; Maze Learning; Mecamylamine; Mice; Nicotine; Pyrroles; Substance Withdrawal Syndrome

2013
Withdrawal of statin treatment abrogates stroke protection in mice.
    Stroke, 2003, Volume: 34, Issue:2

    Topics: Animals; Aorta; Atorvastatin; Bleeding Time; Blood Coagulation; Brain; Brain Ischemia; Disease Models, Animal; Drug Administration Schedule; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ligation; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Platelet Activation; Pyrroles; rhoA GTP-Binding Protein; RNA, Messenger; Stroke; Substance Withdrawal Syndrome; Vena Cava, Inferior; Venous Thrombosis

2003
Buprenorphine and a CRF1 antagonist block the acquisition of opiate withdrawal-induced conditioned place aversion in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:1

    Topics: Acamprosate; Analgesics, Opioid; Animals; Antidepressive Agents, Second-Generation; Avoidance Learning; Buprenorphine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Implants; Fluoxetine; Lisuride; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Substance Withdrawal Syndrome; Taurine

2005
Effect of withdrawal of statin on C-reactive protein.
    Cardiology, 2004, Volume: 102, Issue:3

    Topics: Aged; Atorvastatin; C-Reactive Protein; Coronary Artery Disease; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Lipids; Male; Middle Aged; Pyrroles; Risk Factors; Substance Withdrawal Syndrome

2004
Effects of L-745,870, a dopamine D4 receptor antagonist, on naloxone-induced morphine dependence in mice.
    Annals of the New York Academy of Sciences, 2004, Volume: 1025

    Topics: Animals; Cyclic AMP; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Male; Mice; Morphine Dependence; Naloxone; Pyridines; Pyrroles; Receptors, Dopamine D2; Receptors, Dopamine D4; Substance Withdrawal Syndrome

2004
Prior multiple ethanol withdrawals enhance stress-induced anxiety-like behavior: inhibition by CRF1- and benzodiazepine-receptor antagonists and a 5-HT1a-receptor agonist.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:9

    Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Buspirone; Central Nervous System Depressants; Drug Interactions; Ethanol; Flumazenil; Food, Formulated; GABA Modulators; Interpersonal Relations; Male; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Restraint, Physical; Serotonin Receptor Agonists; Stress, Psychological; Substance Withdrawal Syndrome; Time Factors

2005
Effect of atorvastatin withdrawal on circulating coenzyme Q10 concentration in patients with hypercholesterolemia.
    BioFactors (Oxford, England), 2006, Volume: 28, Issue:3-4

    Topics: Atorvastatin; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Coenzymes; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Pyrroles; Substance Withdrawal Syndrome; Triglycerides; Ubiquinone

2006
Effect of statin withdrawal on frequency of cardiac events after vascular surgery.
    The American journal of cardiology, 2007, Jul-15, Volume: 100, Issue:2

    Topics: Aged; Atorvastatin; Electrocardiography; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heart Diseases; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Middle Aged; Myocardial Infarction; Postoperative Complications; Pravastatin; Pyrroles; Simvastatin; Substance Withdrawal Syndrome; Troponin T; Vascular Surgical Procedures

2007
Discontinuation of statin therapy and clinical outcome after ischemic stroke.
    Stroke, 2007, Volume: 38, Issue:10

    Topics: Aged; Atorvastatin; Brain Ischemia; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Pyrroles; Simvastatin; Stroke; Substance Withdrawal Syndrome

2007
Comparison of the opioid receptor antagonist properties of naltrexone and 6 beta-naltrexol in morphine-naïve and morphine-dependent mice.
    European journal of pharmacology, 2008, Mar-31, Volume: 583, Issue:1

    Topics: Animals; Binding, Competitive; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred ICR; Morphinans; Morphine; Morphine Dependence; Naltrexone; Narcotic Antagonists; Narcotics; Pain Measurement; Pyrroles; Receptors, Opioid, mu; Substance Withdrawal Syndrome

2008
ATP-sensitive K+ channel openers inhibit morphine withdrawal.
    European journal of pharmacology, 1994, Jan-04, Volume: 251, Issue:1

    Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Benzopyrans; Body Weight; Cromakalim; Diazoxide; Dose-Response Relationship, Drug; Female; Injections, Intraventricular; Injections, Subcutaneous; Mice; Mice, Inbred Strains; Morphine; Naloxone; Potassium Channels; Pyrroles; Substance Withdrawal Syndrome

1994
Modification of the expression of naloxone-precipitated withdrawal signs in morphine-dependent mice by diabetes: possible involvement of protein kinase C.
    Japanese journal of pharmacology, 1999, Volume: 79, Issue:3

    Topics: Animals; Behavior, Animal; Carbazoles; Carcinogens; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Frontal Lobe; Indoles; Male; Mice; Mice, Inbred ICR; Morphine; Morphine Dependence; Naloxone; Naphthalenes; Narcotic Antagonists; Narcotics; Norepinephrine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyrroles; Substance Withdrawal Syndrome

1999
Role of corticotropin-releasing factor receptor-1 in opiate withdrawal.
    Journal of neurochemistry, 2000, Volume: 74, Issue:1

    Topics: Animals; Behavior, Animal; Male; Morphine; Naltrexone; Narcotic Antagonists; Protein Isoforms; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Substance Withdrawal Syndrome

2000
Differential roles of corticotropin-releasing factor receptor subtypes 1 and 2 in opiate withdrawal and in relapse to opiate dependence.
    The European journal of neuroscience, 2000, Volume: 12, Issue:12

    Topics: Animals; Cerebral Ventricles; Choice Behavior; Corticotropin-Releasing Hormone; Hormone Antagonists; Injections, Intraventricular; Male; Morphine; Morphine Dependence; Naloxone; Peptide Fragments; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Substance Withdrawal Syndrome

2000