pyrroles has been researched along with Diffuse Large B-Cell Lymphoma in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 13 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anjum, R; Culshaw, J; Davies, NL; Davies, RDM; Degorce, SL; Dillman, KS; Dowling, JE; Drew, L; Ferguson, AD; Groombridge, SD; Halsall, CT; Hudson, JA; Lamont, S; Lindsay, NA; Marden, SK; Mayo, MF; McWhirter, C; Pease, JE; Perkins, DR; Pink, JH; Robb, GR; Rosen, A; Scott, JS; Shen, M; Wu, D | 1 |
| Anjum, R; Degorce, SL; Dillman, KS; Drew, L; Groombridge, SD; Halsall, CT; Lenz, EM; Lindsay, NA; Mayo, MF; Pink, JH; Robb, GR; Scott, JS; Stokes, S; Xue, Y | 1 |
| Bu, W; Chang, G; Chang, S; Dai, B; Hou, J; Hu, L; Kong, Y; Lan, X; Shi, J; Tao, Y; Wang, Y; Wei, Q; Wu, H; Xiao, W; Xie, B; Xie, Y; Yang, G; Yu, D; Zheng, J | 1 |
| Barr, PM; Boyd, T; Caimi, PF; Carret, AS; Chen, R; Chhabra, S; Gartner, EM; Kingsley, EC; Kolibaba, K; Li, H; Park, SI; Phillips, T; Smith, DC; Yu, C | 1 |
| Fellowes, A; Hanna, DM; Hansford, JR; Mechinaud, F; Vedururu, R | 1 |
| Axelson, M; Berglund, M; Delforoush, M; Enblad, G; Feng, X; Georgii-Hemming, P; Larsson, O; Lennartsson, J; Lin, Y; Strömberg, T | 1 |
| Cerchietti, L; Dupont, T; Hatzi, K; Leonard, J; Malik, A; Martin, P; Melnick, A; Patel, J; Tam, W; Yang, SN | 1 |
| Barry, ST; Berdel, WE; Cruzalegui, F; Dai, B; Davies, BR; Erdmann, K; Erdmann, T; Grau, M; Grondine, M; Hudson, K; Klener, P; Lenz, G; Lenz, P; Lynch, JT; Mayo, M; Molinsky, J; Ott, G; Pfeifer, M; Polanska, UM; Schwammbach, D; Staiger, AM; Trneny, M; Tuskova, D; Vočková, P; Zapukhlyak, M | 1 |
| Chu, DT | 1 |
| Chen, L; Dörken, B; Enns, A; Lenz, G; Lenz, P; Loo, A; Naylor, TL; Ratsch, BA; Schuler, W; Stegmeier, F; Tang, H; Warmuth, M; Waters, NJ; Yao, YM | 1 |
| Al-Tourah, AJ; Buckstein, R; Chua, N; Crump, M; Eisenhauer, EA; Foo, AH; Ivy, SP; Kuruvilla, J; Lee, C; Macdonald, DA; Walsh, W | 1 |
| Bhat, S; Brem, EA; Campagna, R; Czuczman, MS; Deeb, G; Fetterly, G; Gibbs, JF; Gu, J; Hernandez-Ilizaliturri, FJ; Hoskin, P; Iqbal, A; Khubchandani, S; Knight, J; Mavis, C; Olejniczak, SH; Riaz, W; Thudium, K; Tsai, PC | 1 |
| Attkisson, E; Dasmahapatra, G; Dent, P; Fisher, RI; Friedberg, JW; Grant, S; Lembersky, D; Patel, H; Peterson, D; Son, MP | 1 |
1 review(s) available for pyrroles and Diffuse Large B-Cell Lymphoma
| Article | Year |
|---|---|
[Clinical manifestation of targeted drugs in individualized therapy of malignant tumors].
Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cyclophosphamide; Doxorubicin; Drug Delivery Systems; ErbB Receptors; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid; Lymphoma, Large B-Cell, Diffuse; Mutation; Neoplasms; Piperazines; Prednisone; Pyrimidines; Pyrroles; Remission Induction; Rituximab; Sunitinib; Vincristine | 2010 |
2 trial(s) available for pyrroles and Diffuse Large B-Cell Lymphoma
| Article | Year |
|---|---|
A phase 1 trial of SGN-CD70A in patients with CD70-positive diffuse large B cell lymphoma and mantle cell lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Benzodiazepines; Biomarkers, Tumor; CD27 Ligand; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Humans; Immunoconjugates; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Pyrroles; Salvage Therapy; Tissue Distribution | 2019 |
Sunitinib in relapsed or refractory diffuse large B-cell lymphoma: a clinical and pharmacodynamic phase II multicenter study of the NCIC Clinical Trials Group.
Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antineoplastic Agents; Female; Humans; Indoles; Lymphoma, Large B-Cell, Diffuse; Male; Middle Aged; Neutropenia; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Salvage Therapy; Sunitinib; Thrombocytopenia; Treatment Failure; Tumor Burden | 2011 |
10 other study(ies) available for pyrroles and Diffuse Large B-Cell Lymphoma
| Article | Year |
|---|---|
Discovery and Optimization of Pyrrolopyrimidine Inhibitors of Interleukin-1 Receptor Associated Kinase 4 (IRAK4) for the Treatment of Mutant MYD88
Topics: Administration, Oral; Animals; Antineoplastic Agents; Cell Line, Tumor; Crystallography, X-Ray; Dogs; Female; Humans; Interleukin-1 Receptor-Associated Kinases; Lymphoma, Large B-Cell, Diffuse; Magnetic Resonance Spectroscopy; Male; Mice, SCID; Mutation; Myeloid Differentiation Factor 88; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Rats, Wistar; Structure-Activity Relationship; Xenograft Model Antitumor Assays | 2017 |
Optimization of permeability in a series of pyrrolotriazine inhibitors of IRAK4.
Topics: Animals; Binding Sites; Caco-2 Cells; Dogs; Drug Design; Half-Life; Hepatocytes; Humans; Interleukin-1 Receptor-Associated Kinases; Lymphoma, Large B-Cell, Diffuse; Molecular Dynamics Simulation; Mutation; Myeloid Differentiation Factor 88; Permeability; Protein Kinases; Pyrroles; Rats; Structure-Activity Relationship; Thiazines | 2018 |
PKC inhibition of sotrastaurin has antitumor activity in diffuse large B-cell lymphoma via regulating the expression of MCT-1.
Topics: Animals; Apoptosis; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Gene Silencing; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Oncogene Proteins; Protein Kinase C; Pyrroles; Quinazolines; RNA, Messenger; RNA, Small Interfering; Signal Transduction | 2018 |
A unique case of refractory primary mediastinal B-cell lymphoma with JAK3 mutation and the role for targeted therapy.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Female; Gene Expression Regulation, Neoplastic; Humans; Janus Kinase 3; Lymphoma, Large B-Cell, Diffuse; Mediastinal Neoplasms; Molecular Targeted Therapy; Mutation; Piperidines; Prednisone; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Signal Transduction; Stem Cell Transplantation; Transplantation, Homologous; Vincristine | 2014 |
Picropodophyllin inhibits proliferation and survival of diffuse large B-cell lymphoma cells.
Topics: Apoptosis; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Lymphoma, Large B-Cell, Diffuse; MAP Kinase Signaling System; Phosphorylation; Podophyllotoxin; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Receptor, IGF Type 1; Signal Transduction | 2015 |
Selective targeting of BCL6 induces oncogene addiction switching to BCL2 in B-cell lymphoma.
Topics: Animals; Biphenyl Compounds; Blotting, Western; Cell Proliferation; Drug Resistance, Neoplasm; Humans; Indoles; Lymphoma, Large B-Cell, Diffuse; Male; Mice; Mice, Nude; Nitrophenols; Peptide Fragments; Piperazines; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-bcl-6; Pyrroles; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Sulfonamides; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2016 |
Sensitivity to PI3K and AKT inhibitors is mediated by divergent molecular mechanisms in subtypes of DLBCL.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Antineoplastic Agents; Apoptosis; Drug Combinations; Drug Screening Assays, Antitumor; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Lymphoma, Large B-Cell, Diffuse; Mice; NF-kappa B; Organ Specificity; Oxadiazoles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Piperidines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; PTEN Phosphohydrolase; Pyrazoles; Pyrimidines; Pyrroles; Signal Transduction; Xenograft Model Antitumor Assays | 2017 |
Protein kinase C inhibitor sotrastaurin selectively inhibits the growth of CD79 mutant diffuse large B-cell lymphomas.
Topics: Animals; CARD Signaling Adaptor Proteins; CD79 Antigens; Cell Growth Processes; Cell Line, Tumor; G1 Phase; Guanylate Cyclase; Humans; Lymphoma, Large B-Cell, Diffuse; Mice; Mutation; NF-kappa B; Protein Kinase C; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcr; Pyrroles; Quinazolines; Signal Transduction | 2011 |
Distinct cellular and therapeutic effects of obatoclax in rituximab-sensitive and -resistant lymphomas.
Topics: Antibodies, Monoclonal, Murine-Derived; Antibody-Dependent Cell Cytotoxicity; Antineoplastic Combined Chemotherapy Protocols; Apoptosis Regulatory Proteins; Autophagy; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Caspases; Cell Death; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Drug Synergism; Humans; Indoles; Lymphoma, B-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Neoplasm Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Rituximab; Tumor Cells, Cultured; Up-Regulation | 2011 |
Obatoclax interacts synergistically with the irreversible proteasome inhibitor carfilzomib in GC- and ABC-DLBCL cells in vitro and in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Bcl-2-Like Protein 11; Cell Line, Tumor; Drug Synergism; Germinal Center; Histones; Humans; Indoles; Lymphoma, Large B-Cell, Diffuse; MAP Kinase Kinase 4; Membrane Proteins; Mice; Mice, Nude; Myeloid Cell Leukemia Sequence 1 Protein; Oligopeptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Xenograft Model Antitumor Assays | 2012 |